nasal bone

Summary

Summary: Either one of the two small elongated rectangular bones that together form the bridge of the nose.

Top Publications

  1. Kagan K, Cicero S, Staboulidou I, Wright D, Nicolaides K. Fetal nasal bone in screening for trisomies 21, 18 and 13 and Turner syndrome at 11-13 weeks of gestation. Ultrasound Obstet Gynecol. 2009;33:259-64 pubmed publisher
    To investigate the performance of first-trimester screening for aneuploidies by including assessment of the fetal nasal bone in the combined test of maternal age, fetal nuchal translucency (NT) thickness, fetal heart rate (FHR) and serum ..
  2. Ozer A, Ozaksit G, Kanat Pektas M, Ozer S. First trimester examination of fetal nasal bone in the Turkish population. J Obstet Gynaecol Res. 2010;36:739-44 pubmed publisher
    The present study aims to assign the reference values for nasal bone length (NBL) screened at 11-14 weeks of pregnancy in the Turkish population, determining whether the NBLs specified for Caucasians can be validated for Turkish people.
  3. De Jong Pleij E, Vos F, Ribbert L, Pistorius L, Tromp E, Bilardo C. Prenasal thickness-to-nasal bone length ratio: a strong and simple second- and third-trimester marker for trisomy 21. Ultrasound Obstet Gynecol. 2012;39:185-90 pubmed publisher
    To study the ratio of prenasal thickness (PT) to nasal bone length (NBL) in normal and trisomy-21 fetuses in the second and third trimesters of pregnancy.
  4. Persico N, Molina F, Azumendi G, Fedele L, Nicolaides K. Nasal bone assessment in fetuses with trisomy 21 at 16-24 weeks of gestation by three-dimensional ultrasound. Prenat Diagn. 2012;32:240-4 pubmed publisher
    ..This study aims to investigate the length and shape of the nasal bones in fetuses with trisomy 21 at 16-24 weeks' gestation...
  5. Gonzalez R, Aedo S, Dezerega V, Sepulveda W. Frontonasal fold thickness-to-nasal bone length ratio as a prenatal sonographic marker for trisomy 21 in a low-risk population. J Ultrasound Med. 2013;32:795-800 pubmed publisher
    To report normative data for the fetal nasal bone length (NBL), frontonasal fold (FNF) thickness, and the FNF/NBL ratio and to study their performance in the sonographic screening of trisomy 21 in a normal, unselected Latin American ..
  6. Chiu W, Tung T, Chen Y, Wang W, Lee S, Horng S, et al. Normative curves of fetal nasal bone length for the ethnic Chinese population. Ir J Med Sci. 2011;180:73-7 pubmed publisher
    The purpose of this study is to determine the association between fetal nasal bone length (NBL) and gestational age (GA), biparietal diameter (BPD) and head circumference (HC) in women undergoing prenatal assessments and Down syndrome ..
  7. Yañez Vico R, Iglesias Linares A, Torres Lagares D, Gutierrez Perez J, Solano Reina E. Three-dimensional evaluation of craniofacial asymmetry: an analysis using computed tomography. Clin Oral Investig. 2011;15:729-36 pubmed publisher
    ..The angulation of the mandibular ramus, on both frontal and lateral planes, determines apparent facial asymmetry, as well as conditioning the surgical treatment plan for patients with craniofacial asymmetry...
  8. Han D, Han Y, Park J. A new approach to the treatment of nasal bone fracture: the clinical usefulness of closed reduction using a C-arm. J Plast Reconstr Aesthet Surg. 2011;64:937-43 pubmed publisher
    Closed reduction is commonly conducted for the treatment of a nasal bone fracture unless a concurrent fracture or a severe nasal septum fracture is observed...
  9. Geipel A, Willruth A, Vieten J, Gembruch U, Berg C. Nuchal fold thickness, nasal bone absence or hypoplasia, ductus venosus reversed flow and tricuspid valve regurgitation in screening for trisomies 21, 18 and 13 in the early second trimester. Ultrasound Obstet Gynecol. 2010;35:535-9 pubmed publisher
    To investigate the performance of nuchal fold thickness, nasal bone hypoplasia, reversed flow in the ductus venosus and tricuspid valve regurgitation in the prediction of fetal aneuploidies in the early second trimester.

More Information

Publications62

  1. Chen X, Lee H, Chong V, Wang D. Assessments of nasal bone fracture effects on nasal airflow: A computational fluid dynamics study. Am J Rhinol Allergy. 2011;25:e39-43 pubmed publisher
    The aim of this study was to evaluate effects of nasal bone fractures on nasal aerodynamic flow patterns using computational fluid dynamics (CFD) simulations.
  2. Kang S, Kim J. Proposed method for closed reduction of impacted nasal bone fractures using a Kirschner wire and a C-arm. J Oral Maxillofac Surg. 2012;70:1393-7 pubmed publisher
    Closed reduction is commonly used for the treatment of nasal bone fractures. If the fracture is impacted, accurate reduction is difficult. Therefore open reduction is often required.
  3. Casasbuenas A, Wong A, Sepulveda W. First-trimester nasal bone length in a normal Latin American population. Prenat Diagn. 2009;29:108-12 pubmed publisher
    To report normative data of nasal bone length (NBL) in first-trimester singleton fetuses in a normal cohort of Latin American women.
  4. Cicero S, Longo D, Rembouskos G, Sacchini C, Nicolaides K. Absent nasal bone at 11-14 weeks of gestation and chromosomal defects. Ultrasound Obstet Gynecol. 2003;22:31-5 pubmed
    To examine the association between absence of the nasal bone at the 11-14-week ultrasound scan and chromosomal defects.
  5. Cicero S, Bindra R, Rembouskos G, Tripsanas C, Nicolaides K. Fetal nasal bone length in chromosomally normal and abnormal fetuses at 11-14 weeks of gestation. J Matern Fetal Neonatal Med. 2002;11:400-2 pubmed
    To determine the value of measuring fetal nasal bone length at 11-14 weeks of gestation in screening for chromosomal defects.
  6. Chen M, Lee C, Tang R, Chan B, Ou C, Tang M. First-trimester examination of fetal nasal bone in the Chinese population. Prenat Diagn. 2006;26:703-6 pubmed
    Absence of the nasal bone in fetuses with trisomy 21 is a potential ultrasound marker for Down syndrome from the first trimester onwards. Racial differences in fetal nasal bone length have been reported...
  7. Maymon R, Levinsohn Tavor O, Cuckle H, Tovbin Y, Dreazen E, Wiener Y, et al. Second trimester ultrasound prenasal thickness combined with nasal bone length: a new method of Down syndrome screening. Prenat Diagn. 2005;25:906-11 pubmed
    To evaluate ultrasound prenasal thickness (PT) as a way of enhancing the Down syndrome (DS) screening performance of second-trimester nasal bone (NB) length measurement.
  8. Nicolaides K. Nuchal translucency and other first-trimester sonographic markers of chromosomal abnormalities. Am J Obstet Gynecol. 2004;191:45-67 pubmed
    ..with 15,822 pregnancies, which included 397 fetuses with trisomy 21, have demonstrated that the absence of the nasal bone can identify 69.0% of trisomy 21 fetuses, which represents a false-positive rate of 1.4%...
  9. Bekker M, Twisk J, van Vugt J. Reproducibility of the fetal nasal bone length measurement. J Ultrasound Med. 2004;23:1613-8 pubmed
    To investigate the reproducibility of the fetal nasal bone length measurement in the first trimester.
  10. Malone F, Ball R, Nyberg D, Comstock C, Saade G, Berkowitz R, et al. First-trimester nasal bone evaluation for aneuploidy in the general population. Obstet Gynecol. 2004;104:1222-8 pubmed
    To evaluate the role of fetal nasal bone imaging at 10 3/7 to 13 6/7 weeks as a screening tool for aneuploidy, in a prospective multicenter trial.
  11. Sonek J, Cicero S, Neiger R, Nicolaides K. Nasal bone assessment in prenatal screening for trisomy 21. Am J Obstet Gynecol. 2006;195:1219-30 pubmed
    ..Evidence based on radiologic, histomorphologic, and sonographic studies shows that nasal bone abnormalities are significantly more common in trisomy 21 fetuses than in euploid fetuses...
  12. Kanagawa T, Fukuda H, Kinugasa Y, Son M, Shimoya K, Murata Y, et al. Mid-second trimester measurement of fetal nasal bone length in the Japanese population. J Obstet Gynaecol Res. 2006;32:403-7 pubmed
    We carried out a preliminary study to compare the nasal bone length (NBL) and biparietal diameter/NBL (BPD/NBL) ratio between the Japanese and white populations.
  13. Gamez F, Ferreiro P, Salmeán J. Ultrasonographic measurement of fetal nasal bone in a low-risk population at 19-22 gestational weeks. Ultrasound Obstet Gynecol. 2004;23:152-3 pubmed
    To determine the potential value of sonographic measurement of fetal nasal bone at 19-22 weeks' gestation in screening for trisomy 21 in a low-risk population.
  14. Cicero S, Dezerega V, Andrade E, Scheier M, Nicolaides K. Learning curve for sonographic examination of the fetal nasal bone at 11-14 weeks. Ultrasound Obstet Gynecol. 2003;22:135-7 pubmed
    To determine the number of ultrasound examinations necessary for training sonographers to examine accurately the fetal nasal bone at 11-14 weeks' gestation.
  15. Cicero S, Bindra R, Rembouskos G, Spencer K, Nicolaides K. Integrated ultrasound and biochemical screening for trisomy 21 using fetal nuchal translucency, absent fetal nasal bone, free beta-hCG and PAPP-A at 11 to 14 weeks. Prenat Diagn. 2003;23:306-10 pubmed
    ..Recent evidence suggests that in about 70% of fetuses with trisomy 21, the nasal bone is not visible at the 11th- to 14th-week scan (Cicero et al., 2001)...
  16. Lee W, DeVore G, Comstock C, Kalache K, McNie B, Chaiworapongsa T, et al. Nasal bone evaluation in fetuses with Down syndrome during the second and third trimesters of pregnancy. J Ultrasound Med. 2003;22:55-60 pubmed
    This study examined the use of three-dimensional ultrasonography for evaluating the fetal nasal bone, as a sonographic marker of Down syndrome, during the second and early third trimesters of pregnancy.
  17. Harshbarger R, Sullivan P. The optimal medial osteotomy: a study of nasal bone thickness and fracture patterns. Plast Reconstr Surg. 2001;108:2114-9; discussion 2120-1 pubmed
    ..The present study was undertaken to understand nasal bone thickness and osteotomy fracture tendencies to provide consistent and aesthetically pleasing results when ..
  18. Cicero S, Curcio P, Papageorghiou A, Sonek J, Nicolaides K. Absence of nasal bone in fetuses with trisomy 21 at 11-14 weeks of gestation: an observational study. Lancet. 2001;358:1665-7 pubmed
    ..In this study, we examined the possible improvement in screening for trisomy 21 by examining the fetal nasal bone with ultrasound at 11-14 weeks of gestation.
  19. Viora E, Errante G, Sciarrone A, Bastonero S, Masturzo B, Martiny G, et al. Fetal nasal bone and trisomy 21 in the second trimester. Prenat Diagn. 2005;25:511-5 pubmed
    To assess the feasibility of measuring nasal bone length in the second trimester of pregnancy and to confirm if fetal nasal bone absence or hypoplasia is a marker for Down syndrome.
  20. Hansen L, Skovgaard L, Nolting D, Hansen B, Kjaer I. Human prenatal nasal bone lengths: normal standards and length values in fetuses with cleft lip and cleft palate. Cleft Palate Craniofac J. 2005;42:165-70 pubmed
    The aim of this study was to present prenatal autopsy standards for nasal bone length in normal fetuses, as well as to compare nasal bone lengths in human fetuses with cleft lip and palate with those standards.
  21. Nielsen B, Mølsted K, Skovgaard L, Kjaer I. Cross-sectional study of the length of the nasal bone in cleft lip and palate subjects. Cleft Palate Craniofac J. 2005;42:417-22 pubmed
    The purpose of this study was to analyze the human nasal bone length in newborns and male adults with cleft lip (CL), cleft palate (CP), and unilateral cleft lip and palate (UCLP) and to compare the results to previous findings in ..
  22. Cossi P, Bussamra L, Araujo Júnior E, Nardozza L, Moron A. Ethnic variation and variability of fetal nasal bone length at 11-15 weeks of gestation in a Brazilian population: preliminary results. Arch Gynecol Obstet. 2008;278:431-5 pubmed publisher
    To evaluate the maternal ethnic influence and the intra and interobserver reproducibility of the nasal bone length measurement at 11-15 weeks of gestation in a Brazilian population.
  23. Cicero S, Avgidou K, Rembouskos G, Kagan K, Nicolaides K. Nasal bone in first-trimester screening for trisomy 21. Am J Obstet Gynecol. 2006;195:109-14 pubmed
    This study was undertaken to investigate the impact of incorporating assessment of the nasal bone into first-trimester combined screening by fetal nuchal translucency (NT) thickness and maternal serum biochemistry.
  24. Odibo A, Sehdev H, Stamilio D, Cahill A, Dunn L, Macones G. Defining nasal bone hypoplasia in second-trimester Down syndrome screening: does the use of multiples of the median improve screening efficacy?. Am J Obstet Gynecol. 2007;197:361.e1-4 pubmed
    The purpose of this study was to compare the efficacy of the use of nasal bone (NB) multiples of the median (MoM) with the biparietal diameter (BPD)/NB ratio as definitions of NB hypoplasia that is associated with Down syndrome in the ..
  25. Baujat B, Attal P, Racy E, Quillard J, Parker F, Evennou A, et al. Chondromyxoid fibroma of the nasal bone with extension into the frontal and ethmoidal sinuses: report of one case and a review of the literature. Am J Otolaryngol. 2001;22:150-3 pubmed
    ..A 50-year-old patient presented with chondromyxoid fibroma of the nasal bone with extension into the frontal and ethmoidal sinuses...
  26. Isobe M, Murakami G, Kataura A. Variations of the uncinate process of the lateral nasal wall with clinical implications. Clin Anat. 1998;11:295-303 pubmed
    ..Attention should be paid to the sphenopalatine artery, which goes through the posterior edge of the middle concha. Four additional variations (combinations of the above basic types, Variations IS, IP, SP, and ISP) were also observed...
  27. Sreedharan S, Kamath M, Hegde M, Sundar S, Lobo F, Raju P. Chondroma of the nasal bone: a case report. Ear Nose Throat J. 2006;85:44-6 pubmed
    ..In this article, the authors describe a new case in which a chondroma of the nasal bone caused an external nasal deformity in a 17-year-old boy...
  28. Cicero S, Sonek J, McKenna D, Croom C, Johnson L, Nicolaides K. Nasal bone hypoplasia in trisomy 21 at 15-22 weeks' gestation. Ultrasound Obstet Gynecol. 2003;21:15-8 pubmed
    To investigate the potential value of ultrasound examination of the fetal profile for present/hypoplastic fetal nasal bone at 15-22 weeks' gestation as a marker for trisomy 21.
  29. Monni G, Zoppi M, Ibba R, Floris M, Manca F, Axiana C. Nuchal translucency and nasal bone for trisomy 21 screening: single center experience. Croat Med J. 2005;46:786-91 pubmed
    To evaluate the feasibility and diagnostic accuracy of fetal nuchal translucency and nasal bone assessment at 11-14 weeks for screening of trisomy 21 at a single center.
  30. Kanellopoulos V, Katsetos C, Economides D. Examination of fetal nasal bone and repeatability of measurement in early pregnancy. Ultrasound Obstet Gynecol. 2003;22:131-4 pubmed
    To evaluate the examination and measurement of fetal nasal bone at 10-14 weeks of gestation.
  31. Senat M, Bernard J, Boulvain M, Ville Y. Intra- and interoperator variability in fetal nasal bone assessment at 11-14 weeks of gestation. Ultrasound Obstet Gynecol. 2003;22:138-41 pubmed
    ..The aim of this study was to assess the intraobserver and interobserver reproducibility of fetal nasal bone identification by ultrasound between 11 and 14 weeks of gestation.
  32. Fujiwara M, Yuba Y, Wada A, Imaoka I, Shintaku N, Miyanishi S. Myofibrosarcoma of the nasal bone. Am J Otolaryngol. 2005;26:265-7 pubmed
    ..This is the first report of such a tumor localized to the glabellar region. This case report contributes to better awareness of an extremely rare type of glabellar lesion in children...
  33. Moon M, Cho J, Lee Y, Lee Y, Yang J, Kim M, et al. Nasal bone length at 11-14 weeks of pregnancy in the Korean population. Prenat Diagn. 2006;26:524-7 pubmed
    The aim of this study was to provide reference values for nasal bone length (NBL) scanned at 11-14 weeks' gestation in the Korean population and compare these values with those of the Caucasian and African-American populations.
  34. Bunduki V, Ruano R, Miguelez J, Yoshizaki C, Kahhale S, Zugaib M. Fetal nasal bone length: reference range and clinical application in ultrasound screening for trisomy 21. Ultrasound Obstet Gynecol. 2003;21:156-60 pubmed
    Fetuses with trisomy 21 typically present with subtle facial abnormalities, including a hypoplastic nasal bone. The aim of this study was to provide a reference range for the length of the fetal nasal bone and to test its value in second-..
  35. Tuxen A, Keeling J, Reintoft I, Fischer Hansen B, Nolting D, Kjaer I. A histological and radiological investigation of the nasal bone in fetuses with Down syndrome. Ultrasound Obstet Gynecol. 2003;22:22-6 pubmed
    Previous studies of nasal bone development in Down syndrome have used radiographs or ultrasound for the detection of nasal bone length or nasal bone absence...
  36. Silvera Q A, Ishii K, Arai T, Morita S, Ono K, Iida A, et al. Long-term results of the two-stage palatoplasty/Hotz' plate approach for complete bilateral cleft lip, alveolus and palate patients. J Craniomaxillofac Surg. 2003;31:215-27 pubmed
    ..To investigate the effects of the two-stage palatoplasty combined with the Hotz' plate on craniofacial development in patients with bilateral complete clefts...
  37. Bethune M. Literature review and suggested protocol for managing ultrasound soft markers for Down syndrome: thickened nuchal fold, echogenic bowel, shortened femur, shortened humerus, pyelectasis and absent or hypoplastic nasal bone. Australas Radiol. 2007;51:218-25 pubmed
    ..fold, echogenic bowel, shortened femur, shortened humerus, pyelectasis (renal pelvis dilatation) and hypoplastic nasal bone is reviewed...
  38. Bremke M, Wiegand S, Sesterhenn A, Eken M, Bien S, Werner J. Digital volume tomography in the diagnosis of nasal bone fractures. Rhinology. 2009;47:126-31 pubmed
    ..The aim of the study was to evaluate, if and in which performance DVT is able to detect discrete nasal bone fractures that cannot be seen in conventional radiography occasionally...
  39. Rhee S, Kim Y, Cha J, Kang S, Park H. Septal fracture in simple nasal bone fracture. Plast Reconstr Surg. 2004;113:45-52 pubmed
    b>Nasal bone fractures are the most common type of facial fractures. Previous studies have shown that most nasal fractures involve the septum, which can provide an obstacle to the successful reduction of nasal bone fractures...
  40. Saito F, Kajii T, Sugawara Kato Y, Tsukamoto Y, Arai Y, Hirabayashi Y, et al. Morphological evaluation of cranial and maxillary shape differences of the brachymorphic mouse with spontaneous malocclusion using three-dimensional micro-computed tomography. Orthod Craniofac Res. 2011;14:100-6 pubmed publisher
    ..The aim of this study was to determine whether significant cranial and maxillary deformity exists in BALB/c-bm/bm (brachymorphism) mouse with spontaneous malocclusion using three-dimensional (3D) images...
  41. Yorgancilar E, Gun R, Yildirim M, Bakir S, Akkus Z, Topcu I. Determination of trigeminocardiac reflex during rhinoplasty. Int J Oral Maxillofac Surg. 2012;41:389-93 pubmed publisher
    ..When an osteotomy is performed or external pressure is applied over the nasal bone, the infraorbital nerve may send signals via this nerve...
  42. Kim J, Lee J, Park C. Cosmetic rhinoseptoplasty in acute nasal bone fracture. Otolaryngol Head Neck Surg. 2013;149:212-8 pubmed publisher
    Traditionally, rhinoseptoplasty for nasal bone fracture is only considered after an unsatisfactory outcome from initial closed reduction...
  43. Ding Y, Zhao J, Deng J, Wang X. Comparison of skeletal changes between female adolescents and adults with hyperdivergent Class II Division 1 malocclusion after orthodontic treatment. Chin J Dent Res. 2012;15:139-44 pubmed
    ..To compare the skeletal changes between female hyperdivergent adolescents and adults with Class II Division 1 malocclusion after orthodontic treatment...
  44. Flores Mir C, Korayem M, Heo G, Witmans M, Major M, Major P. Craniofacial morphological characteristics in children with obstructive sleep apnea syndrome: a systematic review and meta-analysis. J Am Dent Assoc. 2013;144:269-77 pubmed
    ..The authors conducted a systematic review to consolidate the current knowledge regarding craniofacial morphological characteristics associated with obstructive sleep apnea syndrome (OSAS) in nonsyndromic pediatric patients...
  45. Yang I, Moon B, Lee S, Ahn S. Skeletal differences in patients with temporomandibular joint disc displacement according to sagittal jaw relationship. J Oral Maxillofac Surg. 2012;70:e349-60 pubmed publisher
    ..The present study was designed to analyze the skeletal differences in patients with temporomandibular joint (TMJ) disc displacement (DD), according to the sagittal jaw relationship...
  46. Tokutomi J, Hayasaki H, Saitoh I, Iwase Y, Fukami A, Yamada C, et al. Mandibular open-close motion in children with anterior crossbite occlusion. Cranio. 2010;28:10-8 pubmed
    ..The different motions might be related to morphological differences between the two groups...
  47. Hwang K, Kim D. Oblique osteotomy and coronoidectomy in extreme prognathism of Apert syndrome. J Craniofac Surg. 2010;21:555-6 pubmed publisher
    ..It is predictable that there will be a bony impingement between the coronoid process and the subcondyle of the proximal segment before surgery, and so an oblique osteotomy and coronoidectomy are planned ahead through an external approach...
  48. Goynumer G, Yayla M, Durukan B, Wetherilt L. The golden ratio of nasal width to nasal bone length. Clin Exp Obstet Gynecol. 2011;38:50-3 pubmed
    To calculate the ratio of fetal nasal width over nasal bone length at 14-39 weeks' gestation in Caucasian women.
  49. Kim B, Seo H, Kim A, Lee Y, Lee Y, Suh S, et al. The diagnostic value of the sagittal multiplanar reconstruction CT images for nasal bone fractures. Clin Radiol. 2010;65:308-14 pubmed publisher
    To compare the diagnostic performance of sagittal multiplanar reconstruction (MPR) images and axial images for the detection of a nasal bone fracture.
  50. Williams M, Al Zubidi N, Debnam J, Shinder R, DeMonte F, Esmaeli B. Bone invasion by adenoid cystic carcinoma of the lacrimal gland: preoperative imaging assessment and surgical considerations. Ophthalmic Plast Reconstr Surg. 2010;26:403-8 pubmed publisher
    ..To identify the incidence of radiologically and histologically documented bony invasion of the lacrimal gland fossa by adenoid cystic carcinoma...
  51. Persico N, Molina F, Borenstein M, Azumendi G, Nicolaides K. Nasal-bone length in euploid fetuses at 16-24 weeks' gestation by three-dimensional ultrasound. Ultrasound Obstet Gynecol. 2010;36:285-90 pubmed publisher
  52. Saha K, Adhikary D, Shahida S, Biswas S, Islam M, Saha S, et al. Successful outcome of pregnancy with mechanical heart valve with home heparin therapy. Mymensingh Med J. 2012;21:357-9 pubmed
    ..We had successful outcome of pregnancy of a patient with mechanical prosthetic heart valve with home heparin therapy...
  53. Ko E, Huang C, Lo L, Chen Y. Alteration of masticatory electromyographic activity and stability of orthognathic surgery in patients with skeletal class III malocclusion. J Oral Maxillofac Surg. 2013;71:1249-60 pubmed publisher