diaphyses

Summary

Summary: The shaft of long bones.

Top Publications

  1. Macintosh A, Davies T, Ryan T, Shaw C, Stock J. Periosteal versus true cross-sectional geometry: a comparison along humeral, femoral, and tibial diaphyses. Am J Phys Anthropol. 2013;150:442-52 pubmed publisher
    Cross-sectional geometric (CSG) properties of human long bone diaphyses are typically calculated from both periosteal and endosteal contours...
  2. Fitzpatrick D, Doornink J, Madey S, Bottlang M. Relative stability of conventional and locked plating fixation in a model of the osteoporotic femoral diaphysis. Clin Biomech (Bristol, Avon). 2009;24:203-9 pubmed publisher
    ..This study investigated the stiffness and strength of bridge plating with uni-cortical and bi-cortical locking plate constructs relative to a conventional, non-locked construct in the osteoporotic femoral diaphysis...
  3. Stock J, Shaw C. Which measures of diaphyseal robusticity are robust? A comparison of external methods of quantifying the strength of long bone diaphyses to cross-sectional geometric properties. Am J Phys Anthropol. 2007;134:412-23 pubmed
  4. Clapper A, DeYoung B. Chondroblastoma of the femoral diaphysis: report of a rare phenomenon and review of literature. Hum Pathol. 2007;38:803-6 pubmed
    ..We report a case of a CB isolated to the radiologic femoral diaphysis. To our knowledge, this is the first case of a diaphyseal-based CB to be reported in the pathology literature and only the second case published overall...
  5. Hara K, Kobayashi M, Akiyama Y. Influence of bone osteocalcin levels on bone loss induced by ovariectomy in rats. J Bone Miner Metab. 2007;25:345-53 pubmed
    ..These data suggest that long-term reduction in bone OC levels may induce the formation of immature bone, which is easily resorbed with changes in bone metabolism such as OVX, and that OC may be one of the factors affecting bone turnover...
  6. Azorin D, Gonzalez Mediero I, Colmenero I, de Prada I, Lopez Barea F. Diaphyseal chondroblastoma in a long bone: first report. Skeletal Radiol. 2006;35:49-52 pubmed
    ..The patient was a 13-year-old girl who presented with pain over her right thigh. Radiographs showed a lytic lesion in the diaphysis of her right femur. A core biopsy and a subsequent surgical resection were performed...
  7. Stock J, Pfeiffer S. Linking structural variability in long bone diaphyses to habitual behaviors: foragers from the southern African Later Stone Age and the Andaman Islands. Am J Phys Anthropol. 2001;115:337-48 pubmed
    The cross-sectional distribution of cortical bone in long bone diaphyses is highly responsive to mechanical loading during life, yet the relationship between systemic and localized influences on skeletal structure remains unclear...
  8. Barbieri C, Mazzer N, Aranda C, Pinto M. Use of a bone block graft from the iliac crest with rigid fixation to correct diaphyseal defects of the radius and ulna. J Hand Surg Br. 1997;22:395-401 pubmed
    ..We conclude that the technique of bone block grafting to correct diaphyseal defects of the radius or ulna is relatively easy to carry out and has a high success rate...
  9. Ring D, Allende C, Jafarnia K, Allende B, Jupiter J. Ununited diaphyseal forearm fractures with segmental defects: plate fixation and autogenous cancellous bone-grafting. J Bone Joint Surg Am. 2004;86-A:2440-5 pubmed
    ..We reviewed the rate of union and the functional results in association with the use of plate-and-screw fixation and autogenous cancellous (nonstructural) bone grafts...

More Information

Publications62

  1. Deijkers R, Bloem R, Kroon H, Van Lent J, Brand R, Taminiau A. Epidiaphyseal versus other intercalary allografts for tumors of the lower limb. Clin Orthop Relat Res. 2005;439:151-60 pubmed
  2. Viateau V, Guillemin G, Yang Y, Bensaid W, Reviron T, Oudina K, et al. A technique for creating critical-size defects in the metatarsus of sheep for use in investigation of healing of long-bone defects. Am J Vet Res. 2004;65:1653-7 pubmed
    ..To develop a technique for use in investigation of healing of long-bone defects by creation of a critical-size defect in the left metarsal III and IV bone (metatarsus) of sheep...
  3. Carlson K. Investigating the form-function interface in African apes: Relationships between principal moments of area and positional behaviors in femoral and humeral diaphyses. Am J Phys Anthropol. 2005;127:312-34 pubmed
    ..Cross-sectional data from femoral and humeral diaphyses were collected for 222 wild-shot specimens, encompassing Pan paniscus and all commonly recognized African ape ..
  4. Ginn T, Ruch D, Yang C, Hanel D. Use of a distraction plate for distal radial fractures with metaphyseal and diaphyseal comminution. Surgical technique. J Bone Joint Surg Am. 2006;88 Suppl 1 Pt 1:29-36 pubmed
    ..One approach is to apply a dorsal 3.5-mm plate extra-articularly from the radius to the third metacarpal, stabilizing the diaphysis and maintaining distraction across the radiocarpal joint...
  5. Descamps S, Moreel P, Garcier J, Bouillet B, Brehant J, Tanguy A. Existence of a rotational axial component in the human humeral medullary canal. Surg Radiol Anat. 2009;31:579-83 pubmed publisher
    ..We found a constant tri-dimensional spiral shape of the medullary canal in the distal part of the bone. The relations between this first description and the literature are discussed...
  6. Spyridonidis T, Giannakenas C, Barla P, Apostolopoulos D. Erdheim-Chester disease: a rare syndrome with a characteristic bone scintigraphy pattern. Ann Nucl Med. 2008;22:323-6 pubmed publisher
    ..Besides its rarity, the disease has a characteristic almost pathognomonic bone scan appearance, which in some cases facilitates diagnosis of the syndrome. Bone scans also contribute to the qualitative assessment of skeletal involvement...
  7. Dudley Javoroski S, Shields R. Regional cortical and trabecular bone loss after spinal cord injury. J Rehabil Res Dev. 2012;49:1365-76 pubmed
    ..bone mineral density (BMD) in bone epiphyses and a loss of cortical cross-sectional area (CSA) in bone diaphyses, increasing fracture risk for people with SCI...
  8. Koo T, Papuga M. A computer aided method for closed reduction of diaphyseal tibial fracture using projection images: A feasibility study. Comput Aided Surg. 2009;14:45-57 pubmed publisher
    ..It appears that the projection-based reduction method exposes the patient to less radiation and allows for simple, quick and accurate reductions, making it an attractive choice for acute clinical applications...
  9. Reverte M, Dimitriou R, Kanakaris N, Giannoudis P. What is the effect of compartment syndrome and fasciotomies on fracture healing in tibial fractures?. Injury. 2011;42:1402-7 pubmed publisher
    ..Patients with ACS of the tibia undergoing leg fasciotomies should be informed about the increased risk of impaired fracture healing and longer time to union...
  10. Namba Y, Yamazaki Y, Yuguchi M, Kameoka S, Usami S, Honda K, et al. Development of the tarsometatarsal skeleton by the lateral fusion of three cylindrical periosteal bones in the chick embryo (Gallus gallus). Anat Rec (Hoboken). 2010;293:1527-35 pubmed publisher
    ..These findings provide morphological and histological bases for further cellular and molecular studies on this developmental process...
  11. Khan M, Singh A, Singh A, Shrivastava P, Tiwari M, Nagar G, et al. Odanacatib Restores Trabecular Bone of Skeletally Mature Female Rabbits With Osteopenia but Induces Brittleness of Cortical Bone: A Comparative Study of the Investigational Drug With PTH, Estrogen, and Alendronate. J Bone Miner Res. 2016;31:615-29 pubmed publisher
    ..Taken together, we show that ODN reverses BMD, skeletal architecture, and compressive strength in osteopenic rabbits; however, it increases crystallinity and tissue mineralization, thus leading to increased cortical bone brittleness. ..
  12. Monfoulet L, Rabier B, Chassande O, Fricain J. Drilled hole defects in mouse femur as models of intramembranous cortical and cancellous bone regeneration. Calcif Tissue Int. 2010;86:72-81 pubmed publisher
    ..These models enable experimental genetics studies to investigate the cellular and molecular mechanisms of spontaneous cortical and cancellous bone repair and may be useful for pharmacological studies...
  13. Kong C, Kim M, Lee S, Cho W, Song W, Lee J, et al. Prognostic effect of diaphyseal location in osteosarcoma: a cohort case-control study at a single institute. Ann Surg Oncol. 2009;16:3094-100 pubmed publisher
    ..Little is known about the clinical outcome or prognosis of diaphyseal osteosarcoma treated with modern therapeutic strategies...
  14. Claes L, Augat P, Schorlemmer S, Konrads C, Ignatius A, Ehrnthaller C. Temporary distraction and compression of a diaphyseal osteotomy accelerates bone healing. J Orthop Res. 2008;26:772-7 pubmed publisher
    ..There was a significantly higher bone formation rate in the TD group than in the C group. This study demonstrated the feasibility of fracture healing stimulation by the temporary application of distraction and compression...
  15. Ling H, Kwan M, Chua Y, Deepak A, Ahmad T. Locking compression plate: a treatment option for diaphyseal nonunion of radius or ulna. Med J Malaysia. 2006;61 Suppl B:8-12 pubmed
    ..All nonunion united successfully with satisfactory functional outcome. 3.5 mm LCP is effective in the treatment of nonunion of ulna or radius...
  16. Neverov V, Khromov A, Cherniaev S, Egorov K, Shebarshov A. [Treatment of metaphyseal fractures of shin bones by the method of blocking osteosynthesis]. Vestn Khir Im I I Grek. 2008;167:43-7 pubmed
    ..The method provides early functioning of the interfacing joints, early axial loading, shorter period of disability, the absence of external immobilization...
  17. Pinhasi R, Shaw P, White B, Ogden A. Morbidity, rickets and long-bone growth in post-medieval Britain--a cross-population analysis. Ann Hum Biol. 2006;33:372-89 pubmed
    ..There is, however, scarce information on the direct effect of rickets on skeletal growth in either present or past populations...
  18. Liu D, Manske S, Kontulainen S, Tang C, Guy P, Oxland T, et al. Tibial geometry is associated with failure load ex vivo: a MRI, pQCT and DXA study. Osteoporos Int. 2007;18:991-7 pubmed
    ..Bone geometry, assessed by MRI and pQCT, and bone density, assessed by DXA, were significantly associated with bone's mechanical properties. However, cortical density assessed by pQCT was not associated with mechanical properties...
  19. Ahn D. Anatomical study on the diaphyseal nutrient foramen of the femur and tibia of the German shepherd dog. J Vet Med Sci. 2013;75:803-8 pubmed
    ..2 to 38.3% of SI on the lateral border. Their direction of the NC followed Bérard's rule with the exception of the proximal NF of the femur. These results describe the anatomical condition of the NF and NC in the dog. ..
  20. Sales de Gauzy J, Fitoussi F, Jouve J, Karger C, Badina A, Masquelet A. Traumatic diaphyseal bone defects in children. Orthop Traumatol Surg Res. 2012;98:220-6 pubmed publisher
    ..There are no pediatric series in the literature on this topic. The aim of this first pediatric series was to determine the epidemiological characteristics and evaluate the results of different treatments in this entity...
  21. Demirtas A, Azboy I, Durakbasa M, Uçar B, Mercan A, Cakır I. [The relationship between the quadriceps muscle strength and the anterior knee pain occurring after locked intramedullary nailing for tibial diaphysis fractures]. Eklem Hastalik Cerrahisi. 2011;22:81-4 pubmed
    ..The relationship between the quadriceps muscle strength and anterior knee pain occuring after locked tibial intramedullary nailing for tibial shaft (diaphysis) fracture was investigated...
  22. Remer T, Manz F, Alexy U, Schoenau E, Wudy S, Shi L. Long-term high urinary potential renal acid load and low nitrogen excretion predict reduced diaphyseal bone mass and bone size in children. J Clin Endocrinol Metab. 2011;96:2861-8 pubmed publisher
    ..However, studies using valid biomarker measurements of corresponding dietary intakes are lacking...
  23. Spangler L, Ott S, Scholes D. Utility of automated data in identifying femoral shaft and subtrochanteric (diaphyseal) fractures. Osteoporos Int. 2011;22:2523-7 pubmed publisher
    ..00) resulted in a high false-positive rate for identifying femoral diaphyseal fractures. Restriction to more specific site-codes missed 36% of these rare fractures...
  24. Gineyts E, Borel O, Chapurlat R, Garnero P. Quantification of immature and mature collagen crosslinks by liquid chromatography-electrospray ionization mass spectrometry in connective tissues. J Chromatogr B Analyt Technol Biomed Life Sci. 2010;878:1449-54 pubmed publisher
    ..This novel technique should be useful to quantify simultaneously DHLNL, HLNL, PYD and DPD in connective tissues and to evaluate the maturation of collagen by determination of the ratio between immature and mature enzymatic crosslinks...
  25. Kloen P, Wiggers J, Buijze G. Treatment of diaphyseal non-unions of the ulna and radius. Arch Orthop Trauma Surg. 2010;130:1439-45 pubmed publisher
    ..Treatment of these non-unions can be challenging due to poor bone stock, broken hardware, scarring and stiffness due to long-term immobilisation...
  26. O Donnell T, McKenna J, Kenny P, Keogh P, O Flanagan S. Concomitant injuries to the ipsilateral shoulder in patients with a fracture of the diaphysis of the humerus. J Bone Joint Surg Br. 2008;90:61-5 pubmed
    ..These injuries may contribute to pain and dysfunction of the shoulder following treatment, and their presence indicates that antegrade nailing is only partly, if at all, responsible for these symptoms...
  27. Bullens P, Bart Schreuder H, de Waal Malefijt M, Verdonschot N, Buma P. Is an impacted morselized graft in a cage an alternative for reconstructing segmental diaphyseal defects?. Clin Orthop Relat Res. 2009;467:783-91 pubmed publisher
    ..The data suggest that a cage filled with a loaded morselized graft could be an alternative for the massive cortical graft in reconstruction of large diaphyseal defects in an animal model...
  28. Langer J, Gardner M, Ricci W. The cortical step sign as a tool for assessing and correcting rotational deformity in femoral shaft fractures. J Orthop Trauma. 2010;24:82-8 pubmed publisher
    ..This study aims to critically analyze the cortical step sign in cadaveric specimens using radiographic and direct measurements...
  29. Thongchote K, Charoenphandhu N, Krishnamra N. High physiological prolactin induced by pituitary transplantation decreases BMD and BMC in the femoral metaphysis, but not in the diaphysis of adult female rats. J Physiol Sci. 2008;58:39-45 pubmed publisher
    ..e., the metaphysis, of the femora of adult female rats in an estrogen-dependent manner. Since PRL had no detectable effect on the vertebrae, the effects of PRL on bone appeared to be site-specific...
  30. Aronsson D, Stokes I, McBride C. The role of remodeling and asymmetric growth in vertebral wedging. Stud Health Technol Inform. 2010;158:11-5 pubmed
    ..We investigated whether vertebral wedging in scoliosis might involve both mechanisms...
  31. Xiao C, Tang F, Zhou Y, Zhang W, Luo Y, Duan H, et al. A locking compression plate as an external fixator for treating infected nonunion of the humeral diaphysis. BMC Surg. 2016;16:53 pubmed publisher
    ..The novel use of an LCP as a definitive external fixator was an effective method for treating infected nonunion of the humeral diaphysis. However, a large-scale prospective clinical study is still needed to verify these findings. ..
  32. Chen J, Lee C, Coleman R, Yoon J, Lohmann C, Zustin J, et al. Formation of tethers linking the epiphysis and metaphysis is regulated by vitamin d receptor-mediated signaling. Calcif Tissue Int. 2009;85:134-45 pubmed publisher
    ..Overall, these results demonstrate microCT imaging's utility for analyzing tether formation and suggest that signaling via the VDR plays a pivotal role in tether formation...
  33. Rissech C, Márquez Grant N, Turbón D. A collation of recently published Western European formulae for age estimation of subadult skeletal remains: recommendations for forensic anthropology and osteoarchaeology. J Forensic Sci. 2013;58 Suppl 1:S163-8 pubmed publisher
    ..Due to their high reliability and because they derive from documented European skeletal samples, we recommend these formulae be used on individuals of Caucasoid ancestry from Western Europe...
  34. Bubeck K, García López J, Jenei T, Maranda L. In vitro comparison of two centrally threaded, positive-profile transfixation pin designs for use in third metacarpal bones in horses. Am J Vet Res. 2010;71:976-81 pubmed publisher
    ..To compare heat generation during insertion, pullout strength, and associated microdamage between a self-tapping positive profile transfixation pin (STTP) and nontapping positive profile transfixation pin (NTTP)...
  35. Uzel A, Deloumeaux J, Rouvillain J, Laflamme G, Durandeau A, Caix P. Comparative study of femoral diaphyseal morphometry in two male populations, in France and a French West Indies island: an example of clinical relevance of comparative anatomy for orthopedic practice. Surg Radiol Anat. 2011;33:235-40 pubmed publisher
    ..The range of usable implants must be complete and there must be precise pre-operative planning. A study of computed tomography scans could complement our measurements...
  36. Ayturk U, Jacobsen C, Christodoulou D, Gorham J, Seidman J, Seidman C, et al. An RNA-seq protocol to identify mRNA expression changes in mouse diaphyseal bone: applications in mice with bone property altering Lrp5 mutations. J Bone Miner Res. 2013;28:2081-93 pubmed publisher
    ..A214V/+) ) and "insufficient" (Lrp5(-/-) ) diaphyseal bone, and far fewer differentially expressed genes between Lrp5(p.A214V/+) and Lrp5(+/+) diaphyseal bone...
  37. Altan M, Kanter M, Donmez S, Kartal M, Buyukbas S. Combination therapy of Nigella sativa and human parathyroid hormone on bone mass, biomechanical behavior and structure in streptozotocin-induced diabetic rats. Acta Histochem. 2007;109:304-14 pubmed
    ..These results suggest that NS might be used in a similar manner to insulin as a safe and effective therapy for diabetes and might be useful in the treatment of diabetic osteopenia...
  38. Rouhani A, Elmi A, Akbari Aghdam H, Panahi F, Dokht Ghafari Y. The role of fibular fixation in the treatment of tibia diaphysis distal third fractures. Orthop Traumatol Surg Res. 2012;98:868-72 pubmed publisher
    ..There is an ongoing debate about the necessity of fibular fixation when associated to distal third tibial fracture. This study aims at evaluating the role of fibular fixation in the treatment of distal third tibial fractures...
  39. Nakamura T, Abudu A, Grimer R, Carter S, Jeys L, Tillman R. The clinical outcomes of extracorporeal irradiated and re-implanted cemented autologous bone graft of femoral diaphysis after tumour resection. Int Orthop. 2013;37:647-51 pubmed publisher
    ..We report the outcome of intercalary resection of the femoral diaphysis and extracorporeal irradiated autologous bone graft reconstruction, without the use of vascularized fibular graft...
  40. Hsu J, Wang S, Huang H, Chen Y, Wu J, Tsai M. The assessment of trabecular bone parameters and cortical bone strength: a comparison of micro-CT and dental cone-beam CT. J Biomech. 2013;46:2611-8 pubmed publisher
    ..847, respectively) to predict fracture loads. This study has yielded a new method for using dental CBCT to evaluate bone parameters and bone strength; however, further studies are necessary to validate the use of dental CBCT on humans. ..
  41. Sakellariou V, Mavrogenis A, Papagelopoulos P. Limb salvage surgery using the intramedullary diaphyseal segmental defect fixation system. J Long Term Eff Med Implants. 2008;18:59-67 pubmed
    ..8%. The intramedullary diaphyseal segmental defect fixation system used herein is associated with a satisfactory functional and oncological outcome after wide resection of diaphyseal bone tumors...
  42. Palumbo B, Morrison K, Baumgarten A, Stein M, Haidukewych G, Bernasek T. Results of revision total hip arthroplasty with modular, titanium-tapered femoral stems in severe proximal metaphyseal and diaphyseal bone loss. J Arthroplasty. 2013;28:690-4 pubmed publisher
    ..In surviving cases, patients achieved satisfactory function and there were no mechanical failures. Modular, tapered stems demonstrated acceptable outcomes for management of severe proximal metaphyseal and diaphyseal defects...
  43. Chang G, Rajapakse C, Diamond M, Honig S, Recht M, Weiss D, et al. Micro-finite element analysis applied to high-resolution MRI reveals improved bone mechanical competence in the distal femur of female pre-professional dancers. Osteoporos Int. 2013;24:1407-17 pubmed publisher
    ..Greater whole bone stiffness appears to be mediated by cancellous, rather than cortical bone adaptation...
  44. Demirel C, Kilciksiz S, Gurgul S, Erdal N, Yildiz A. N-acetylcysteine ameliorates ?-radiation-induced deterioration of bone quality in the rat femur. J Int Med Res. 2011;39:2393-401 pubmed
    ..These findings indicate that NAC and amifostine preserve bone quality in rats exposed to ?-irradiation...
  45. Cowgill L. The ontogeny of Holocene and Late Pleistocene human postcranial strength. Am J Phys Anthropol. 2010;141:16-37 pubmed publisher
  46. Fischerauer E, Manninger M, Seles M, Janezic G, Pichler K, Ebner B, et al. BMP-6 and BMPR-1a are up-regulated in the growth plate of the fractured tibia. J Orthop Res. 2013;31:357-63 pubmed publisher
  47. Giannoudis P, Faour O, Goff T, Kanakaris N, Dimitriou R. Masquelet technique for the treatment of bone defects: tips-tricks and future directions. Injury. 2011;42:591-8 pubmed publisher
  48. Panzica M, Gosling T, Schandelmaier P, Hankemeier S, Krettek C. Reconstruction of a post-traumatic infected bone defect of an open diaphyseal femur fracture by double LISS fixation: a case report. J Trauma. 2007;62:1272-6 pubmed
  49. Ng A, Drake M, Clarke B, Sems S, Atkinson E, Achenbach S, et al. Trends in subtrochanteric, diaphyseal, and distal femur fractures, 1984-2007. Osteoporos Int. 2012;23:1721-6 pubmed publisher
    ..The incidence of non-hip femur fractures increased between 1984 and 2007, with an increase in the rates for women after 1996...
  50. Horn C, Döbele S, Vester H, Schaffler A, Lucke M, Stöckle U. Combination of interfragmentary screws and locking plates in distal meta-diaphyseal fractures of the tibia: a retrospective, single-centre pilot study. Injury. 2011;42:1031-7 pubmed publisher
    ..We therefore retrospectively assessed our patients for time until clinical fracture healing (i.e., pain-free weight bearing and visible callus in both layers on conventional plain film radiographs) and callus formation...
  51. Mary P, Thevenin Lemoine C. [New surgical procedures in musculoskeletal sarcomas of the child]. Bull Cancer. 2011;98:515-26 pubmed publisher
    ..The choice of reconstruction depends on many factors (age, presence of secondary localizations, chemotherapy tolerance, socioeconomic context…) and can only be conceived as part of multidisciplinary evaluations...
  52. Laurin M, Canoville A, Quilhac A. Use of paleontological and molecular data in supertrees for comparative studies: the example of lissamphibian femoral microanatomy. J Anat. 2009;215:110-23 pubmed publisher
    ..The analyses confirmed previous conclusions about the presence of an ecological signal in bone microanatomical data...
  53. Yildirim A, Oken O, Katı Y, Gulcek M, Ucaner A. Factors affecting the closed reduction of diaphyseal fractures of the femur. Eur J Orthop Surg Traumatol. 2013;23:945-51 pubmed publisher
    ..This level II prospective study investigates patient and fracture-related factors likely to affect closed reduction time in the surgical treatment of femur fractures, and the effect these factors have on closed reduction time...