gastroschisis

Summary

Summary: A congenital defect with major fissure in the ABDOMINAL WALL lateral to, but not at, the UMBILICUS. This results in the extrusion of VISCERA. Unlike OMPHALOCELE, herniated structures in gastroschisis are not covered by a sac or PERITONEUM.

Top Publications

  1. Henrich K, Huemmer H, Reingruber B, Weber P. Gastroschisis and omphalocele: treatments and long-term outcomes. Pediatr Surg Int. 2008;24:167-73 pubmed
    Between February 1994 and April 2004, we treated 40 children with gastroschisis and 26 children with omphalocele...
  2. Mastroiacovo P, Lisi A, Castilla E, Martinez Frias M, Bermejo E, Marengo L, et al. Gastroschisis and associated defects: an international study. Am J Med Genet A. 2007;143A:660-71 pubmed
    Our objective was to evaluate the frequency and type of malformations associated with gastroschisis in a large pool of international data, to identify malformation patterns, and to evaluate the role of maternal age in non-isolated cases...
  3. Root E, Meyer R, Emch M. Evidence of localized clustering of gastroschisis births in North Carolina, 1999-2004. Soc Sci Med. 2009;68:1361-7 pubmed publisher
    ..In North Carolina, the prevalence of gastroschisis, a serious abdominal wall defect, has increased over the past decade and anecdotal evidence from clinicians ..
  4. Owen A, Marven S, Jackson L, Antao B, Roberts J, Walker J, et al. Experience of bedside preformed silo staged reduction and closure for gastroschisis. J Pediatr Surg. 2006;41:1830-5 pubmed
    ..anesthesia (PSnoGA), compared to emergency operative fascial closure (OFC) under general anesthesia for gastroschisis (GS)...
  5. Arnold M, Chang D, Nabaweesi R, Colombani P, Fischer A, Lau H, et al. Development and validation of a risk stratification index to predict death in gastroschisis. J Pediatr Surg. 2007;42:950-5; discussion 955-6 pubmed
    b>Gastroschisis is a rare congenital anomaly, the improved surgical management of which has contributed to a survival rate greater than 90%...
  6. Horton A, Powell M, Wolfe H. Intrauterine growth patterns in fetal gastroschisis. Am J Perinatol. 2010;27:211-7 pubmed publisher
    The objective of this study was to evaluate patterns of intrauterine growth in fetal gastroschisis. This was a retrospective review of prenatally diagnosed cases of fetal gastroschisis delivered at the University of North Carolina ..
  7. Benjamin B, Ethen M, Van Hook C, Myers C, Canfield M. Gastroschisis prevalence in Texas 1999-2003. Birth Defects Res A Clin Mol Teratol. 2010;88:178-85 pubmed publisher
    The worldwide prevalence of gastroschisis is increasing. Maternal age, race/ethnicity, and place of residence have been associated with increased risk...
  8. Williams T. Animal models of ventral body wall closure defects: a personal perspective on gastroschisis. Am J Med Genet C Semin Med Genet. 2008;148C:186-91 pubmed publisher
    Malformations affecting the ventral body wall comprise one of the leading categories of human birth defects. Gastroschisis is a particularly important body wall closure defect as its incidence is rising worldwide...
  9. Rittler M, Castilla E, Chambers C, Lopez Camelo J. Risk for gastroschisis in primigravidity, length of sexual cohabitation, and change in paternity. Birth Defects Res A Clin Mol Teratol. 2007;79:483-7 pubmed
    Maternal epidemiologic similarities between gastroschisis and preeclampsia have led to the objective of evaluating the risk for gastroschisis related to primigravidity, change in paternity, and length of cohabitation, considered as risk ..
  10. Lammer E, Iovannisci D, Tom L, Schultz K, Shaw G. Gastroschisis: a gene-environment model involving the VEGF-NOS3 pathway. Am J Med Genet C Semin Med Genet. 2008;148C:213-8 pubmed publisher
    b>Gastroschisis is a severe major malformation in which an infant is delivered with a portion of intestines and possible other abdominal organs extruding through a defect in the abdominal wall, usually to the right of the umbilical cord...

Detail Information

Publications84

  1. Henrich K, Huemmer H, Reingruber B, Weber P. Gastroschisis and omphalocele: treatments and long-term outcomes. Pediatr Surg Int. 2008;24:167-73 pubmed
    Between February 1994 and April 2004, we treated 40 children with gastroschisis and 26 children with omphalocele...
  2. Mastroiacovo P, Lisi A, Castilla E, Martinez Frias M, Bermejo E, Marengo L, et al. Gastroschisis and associated defects: an international study. Am J Med Genet A. 2007;143A:660-71 pubmed
    Our objective was to evaluate the frequency and type of malformations associated with gastroschisis in a large pool of international data, to identify malformation patterns, and to evaluate the role of maternal age in non-isolated cases...
  3. Root E, Meyer R, Emch M. Evidence of localized clustering of gastroschisis births in North Carolina, 1999-2004. Soc Sci Med. 2009;68:1361-7 pubmed publisher
    ..In North Carolina, the prevalence of gastroschisis, a serious abdominal wall defect, has increased over the past decade and anecdotal evidence from clinicians ..
  4. Owen A, Marven S, Jackson L, Antao B, Roberts J, Walker J, et al. Experience of bedside preformed silo staged reduction and closure for gastroschisis. J Pediatr Surg. 2006;41:1830-5 pubmed
    ..anesthesia (PSnoGA), compared to emergency operative fascial closure (OFC) under general anesthesia for gastroschisis (GS)...
  5. Arnold M, Chang D, Nabaweesi R, Colombani P, Fischer A, Lau H, et al. Development and validation of a risk stratification index to predict death in gastroschisis. J Pediatr Surg. 2007;42:950-5; discussion 955-6 pubmed
    b>Gastroschisis is a rare congenital anomaly, the improved surgical management of which has contributed to a survival rate greater than 90%...
  6. Horton A, Powell M, Wolfe H. Intrauterine growth patterns in fetal gastroschisis. Am J Perinatol. 2010;27:211-7 pubmed publisher
    The objective of this study was to evaluate patterns of intrauterine growth in fetal gastroschisis. This was a retrospective review of prenatally diagnosed cases of fetal gastroschisis delivered at the University of North Carolina ..
  7. Benjamin B, Ethen M, Van Hook C, Myers C, Canfield M. Gastroschisis prevalence in Texas 1999-2003. Birth Defects Res A Clin Mol Teratol. 2010;88:178-85 pubmed publisher
    The worldwide prevalence of gastroschisis is increasing. Maternal age, race/ethnicity, and place of residence have been associated with increased risk...
  8. Williams T. Animal models of ventral body wall closure defects: a personal perspective on gastroschisis. Am J Med Genet C Semin Med Genet. 2008;148C:186-91 pubmed publisher
    Malformations affecting the ventral body wall comprise one of the leading categories of human birth defects. Gastroschisis is a particularly important body wall closure defect as its incidence is rising worldwide...
  9. Rittler M, Castilla E, Chambers C, Lopez Camelo J. Risk for gastroschisis in primigravidity, length of sexual cohabitation, and change in paternity. Birth Defects Res A Clin Mol Teratol. 2007;79:483-7 pubmed
    Maternal epidemiologic similarities between gastroschisis and preeclampsia have led to the objective of evaluating the risk for gastroschisis related to primigravidity, change in paternity, and length of cohabitation, considered as risk ..
  10. Lammer E, Iovannisci D, Tom L, Schultz K, Shaw G. Gastroschisis: a gene-environment model involving the VEGF-NOS3 pathway. Am J Med Genet C Semin Med Genet. 2008;148C:213-8 pubmed publisher
    b>Gastroschisis is a severe major malformation in which an infant is delivered with a portion of intestines and possible other abdominal organs extruding through a defect in the abdominal wall, usually to the right of the umbilical cord...
  11. Payne N, Pfleghaar K, Assel B, Johnson A, Rich R. Predicting the outcome of newborns with gastroschisis. J Pediatr Surg. 2009;44:918-23 pubmed publisher
    The objective of the study was to determine factors predicting outcome in newborns with gastroschisis. A retrospective analysis of 155 consecutive cases admitted from 1 January 1990 to 31 December 2007 was performed...
  12. Werler M. Hypothesis: could Epstein-Barr virus play a role in the development of gastroschisis?. Birth Defects Res A Clin Mol Teratol. 2010;88:71-5 pubmed publisher
    The strong inverse association between maternal age and risk of gastroschisis in offspring has spurred many investigators to hypothesize that behaviors among younger females are the cause...
  13. Kronfli R, Bradnock T, Sabharwal A. Intestinal atresia in association with gastroschisis: a 26-year review. Pediatr Surg Int. 2010;26:891-4 pubmed publisher
    We reviewed our experience with gastroschisis (GS) complicated by intestinal atresia over the last 26 years...
  14. Draper E, Rankin J, Tonks A, Abrams K, Field D, Clarke M, et al. Recreational drug use: a major risk factor for gastroschisis?. Am J Epidemiol. 2008;167:485-91 pubmed
    The authors tested the hypothesis that the birth prevalence of gastroschisis is positively associated with use of recreational drugs in early pregnancy...
  15. Marven S, Owen A. Contemporary postnatal surgical management strategies for congenital abdominal wall defects. Semin Pediatr Surg. 2008;17:222-35 pubmed publisher
    ..Risk stratification may produce outcome and tailor management of difficult cases in the form of a clinical pathway. Stem cell technology may, in the future, offer the ideal allogenic prosthesis in complex cases. ..
  16. Fillingham A, Rankin J. Prevalence, prenatal diagnosis and survival of gastroschisis. Prenat Diagn. 2008;28:1232-7 pubmed publisher
    To describe the prevalence, associated anomalies, prenatal diagnosis and survival of cases of gastroschisis. Data were extracted from the Northern Congenital Abnormality Survey (NorCAS) for cases delivered during 1997 to 2006...
  17. Lobo J, Kim A, Davis R, Segura B, Alpert H, Teitelbaum D, et al. No free ride? The hidden costs of delayed operative management using a spring-loaded silo for gastroschisis. J Pediatr Surg. 2010;45:1426-32 pubmed publisher
    The ideal management of gastroschisis (primary vs staged closure) has not yet been established. Despite the ease of silo placement, anecdotal experience shows that silos do not always offer benefit...
  18. Soares H, Silva A, Rocha G, Pissarra S, Correia Pinto J, Guimaraes H. Gastroschisis: preterm or term delivery?. Clinics (Sao Paulo). 2010;65:139-42 pubmed publisher
    ..to evaluate the association between prematurity and the time to achieve full enteral feeding in newborns with gastroschisis. The second objective was to analyze the associations between length of hospital stay and time to achieve full ..
  19. Richardson S, Browne M, Rasmussen S, Druschel C, Sun L, Jabs E, et al. Associations between periconceptional alcohol consumption and craniosynostosis, omphalocele, and gastroschisis. Birth Defects Res A Clin Mol Teratol. 2011;91:623-30 pubmed publisher
    ..associations between maternal alcohol consumption during pregnancy and craniosynostosis, omphalocele, and gastroschisis among participants in the National Birth Defects Prevention Study, a large, multicenter case-control study...
  20. Holland A, Walker K, Badawi N. Gastroschisis: an update. Pediatr Surg Int. 2010;26:871-8 pubmed publisher
    b>Gastroschisis (GS) continues to increase in frequency, with several studies now reported an incidence of between 4 and 5 per 10,000 live births...
  21. Stoll C, Alembik Y, Dott B, Roth M. Omphalocele and gastroschisis and associated malformations. Am J Med Genet A. 2008;146A:1280-5 pubmed publisher
    The etiology of gastroschisis and omphalocele is unclear and their pathogenesis is controversial...
  22. Lubinsky M. Hypothesis: Estrogen related thrombosis explains the pathogenesis and epidemiology of gastroschisis. Am J Med Genet A. 2012;158A:808-11 pubmed publisher
    A three-part hypothesis is proposed to explain the unusual epidemiology of gastroschisis, a congenital abnormality of the abdominal wall, which has a rising frequency, a higher rate in first and young mothers in whites but not blacks, ..
  23. Castilla E, Mastroiacovo P, Orioli I. Gastroschisis: international epidemiology and public health perspectives. Am J Med Genet C Semin Med Genet. 2008;148C:162-79 pubmed publisher
    b>Gastroschisis offers the intriguing epidemiological situation of a pandemic, strongly associated with very low maternal age...
  24. McGuigan R, Mullenix P, Vegunta R, Pearl R, Sawin R, Azarow K. Splanchnic perfusion pressure: a better predictor of safe primary closure than intraabdominal pressure in neonatal gastroschisis. J Pediatr Surg. 2006;41:901-4 pubmed
    ..and calculated splanchnic perfusion pressure (SPP) have been advocated for use in operative management of gastroschisis. We directly compared these 2 clinical indices...
  25. Feldkamp M, Reefhuis J, Kucik J, Krikov S, Wilson A, Moore C, et al. Case-control study of self reported genitourinary infections and risk of gastroschisis: findings from the national birth defects prevention study, 1997-2003. BMJ. 2008;336:1420-3 pubmed publisher
    ..between genitourinary infections in the month before conception to the end of the first trimesterand gastroschisis. Case-control study with self reported infections from a computer assisted telephone interview...
  26. Allotey J, Davenport M, Njere I, Charlesworth P, Greenough A, Ade Ajayi N, et al. Benefit of preformed silos in the management of gastroschisis. Pediatr Surg Int. 2007;23:1065-9 pubmed
    b>Gastroschisis is traditionally managed by primary closure (PC) or delayed closure after surgical silo placement...
  27. Mousty E, Chalouhi G, El Sabbagh A, Khen Dunlop N, Kuleva M, Salomon L, et al. Secondary bladder herniation in isolated gastroschisis justifies increased surveillance. Prenat Diagn. 2012;32:888-92 pubmed publisher
    To assess the perinatal outcome of fetuses with gastroschisis complicated by secondary bladder herniation...
  28. Pastor A, Phillips J, Fenton S, Meyers R, Lamm A, Raval M, et al. Routine use of a SILASTIC spring-loaded silo for infants with gastroschisis: a multicenter randomized controlled trial. J Pediatr Surg. 2008;43:1807-12 pubmed publisher
    Retrospective studies have suggested that routine use of a preformed silo for infants with gastroschisis may be associated with improved outcomes. We performed a prospective multicenter randomized controlled trial to test this hypothesis.
  29. Loane M, Dolk H, Bradbury I. Increasing prevalence of gastroschisis in Europe 1980-2002: a phenomenon restricted to younger mothers?. Paediatr Perinat Epidemiol. 2007;21:363-9 pubmed
    b>Gastroschisis is an abdominal wall defect more prevalent in offspring of young mothers. It is known to be increasing in prevalence despite the general decrease in the proportion of births to young European women...
  30. Zamakhshary M, Yanchar N. Complicated gastroschisis and maternal smoking: a causal association?. Pediatr Surg Int. 2007;23:841-4 pubmed
    The incidence of gastroschisis appears to be rising in developed nations, with epidemiological studies indicating association with young maternal age and smoking...
  31. Weinsheimer R, Yanchar N, Bouchard S, Kim P, Laberge J, Skarsgard E, et al. Gastroschisis closure--does method really matter?. J Pediatr Surg. 2008;43:874-8 pubmed publisher
    Management of gastroschisis varies. This study aims to determine which aspects of practice influence outcomes.
  32. Tan K, Tan K, Chew S, Yeo G. Gastroschisis and omphalocele in Singapore: a ten-year series from 1993 to 2002. Singapore Med J. 2008;49:31-6 pubmed
    Two of the most common malformations of the anterior abdominal wall include gastroschisis and omphalocele, both of which are associated with high morbidity and mortality. Studies have shown an increase in both conditions worldwide...
  33. Skarsgard E, Claydon J, Bouchard S, Kim P, Lee S, Laberge J, et al. Canadian Pediatric Surgical Network: a population-based pediatric surgery network and database for analyzing surgical birth defects. The first 100 cases of gastroschisis. J Pediatr Surg. 2008;43:30-4; discussion 34 pubmed publisher
    Outcomes studies for gastroschisis are constrained by small numbers, prolonged accrual, and nonstandardized data collection...
  34. van Eijck F, Wijnen R, van Goor H. The incidence and morbidity of adhesions after treatment of neonates with gastroschisis and omphalocele: a 30-year review. J Pediatr Surg. 2008;43:479-83 pubmed publisher
    ..Knowledge of its incidence and potential risk factors in a well-documented group with strict follow-up is needed to guide preventive measures...
  35. Ledbetter D. Gastroschisis and omphalocele. Surg Clin North Am. 2006;86:249-60, vii pubmed
  36. Paranjothy S, Broughton H, Evans A, Huddart S, Drayton M, Jefferson R, et al. The role of maternal nutrition in the aetiology of gastroschisis: an incident case-control study. Int J Epidemiol. 2012;41:1141-52 pubmed publisher
    b>Gastroschisis, a congenital anomaly involving a defect in the fetal abdominal wall, has increased in prevalence in many countries, but the aetiology is uncertain...
  37. Chambers C, Chen B, Kalla K, Jernigan L, Jones K. Novel risk factor in gastroschisis: change of paternity. Am J Med Genet A. 2007;143A:653-9 pubmed
    In recent years, an increase in the rate of gastroschisis has been documented in several countries throughout the world...
  38. Clark R, Walker M, Gauderer M. Factors associated with mortality in neonates with gastroschisis. Eur J Pediatr Surg. 2011;21:21-4 pubmed publisher
    The ongoing epidemic of gastroschisis has created multiple challenges and continues to raise questions concerning the optimal management of these high-risk patients...
  39. Manson J, Ameh E, Canvassar N, Chen T, den Hoeve A, Lever F, et al. Gastroschisis: a multi-centre comparison of management and outcome. Afr J Paediatr Surg. 2012;9:17-21 pubmed publisher
    Anecdotal evidence and a handful of literature reports suggest that the outcome for infants born with gastroschisis in many African countries is poor when compared to Western nations...
  40. Kassa A, Lilja H. Predictors of postnatal outcome in neonates with gastroschisis. J Pediatr Surg. 2011;46:2108-14 pubmed publisher
    The optimal management of neonates with gastroschisis is unclear, and there is a significant morbidity...
  41. Lin S, Munsie J, Herdt Losavio M, Bell E, Druschel C, Romitti P, et al. Maternal asthma medication use and the risk of gastroschisis. Am J Epidemiol. 2008;168:73-9 pubmed publisher
    ..the association between maternal asthma medication use during the periconceptional period and the risk of gastroschisis. In this case-control study, the authors used data on deliveries enrolled in the National Birth Defects ..
  42. Islam S. Clinical care outcomes in abdominal wall defects. Curr Opin Pediatr. 2008;20:305-10 pubmed publisher
    Abdominal wall defects comprising both gastroschisis and omphalocele remain a source of significant morbidity and mortality, despite the advances in neonatal and pediatric surgical care...
  43. Owen A, Marven S, Johnson P, Kurinczuk J, Spark P, Draper E, et al. Gastroschisis: a national cohort study to describe contemporary surgical strategies and outcomes. J Pediatr Surg. 2010;45:1808-16 pubmed publisher
    Information on adoption of newer surgical strategies for gastroschisis and their outcomes is largely limited to hospital-based studies...
  44. Bradnock T, Marven S, Owen A, Johnson P, Kurinczuk J, Spark P, et al. Gastroschisis: one year outcomes from national cohort study. BMJ. 2011;343:d6749 pubmed publisher
    To describe one year outcomes for a national cohort of infants with gastroschisis.
  45. Sadler T. The embryologic origin of ventral body wall defects. Semin Pediatr Surg. 2010;19:209-14 pubmed publisher
    Ventral body wall defects include ectopia cordis, bladder exstrophy, and the abdominal wall malformations gastroschisis and omphalocele...
  46. Mears A, Sadiq J, Impey L, Lakhoo K. Antenatal bowel dilatation in gastroschisis: a bad sign?. Pediatr Surg Int. 2010;26:581-8 pubmed publisher
    Foetal bowel dilatation in gastroschisis is traditionally taken to be an indicator of poor prognosis and parents are counselled accordingly. Increased bowel distension is often a factor in the decision for early delivery...
  47. Houben C, Davenport M, Ade Ajayi N, Flack N, Patel S. Closing gastroschisis: diagnosis, management, and outcomes. J Pediatr Surg. 2009;44:343-7 pubmed publisher
    b>Gastroschisis (GS) is defined as a full-thickness abdominal wall defect (usually right-sided) with intestinal prolapse and occasionally other viscera...
  48. Kumar T, Vaughan R, Polak M. A proposed classification for the spectrum of vanishing gastroschisis. Eur J Pediatr Surg. 2013;23:72-5 pubmed publisher
    Infants born with gastroschisis in association with intestinal atresia are well described. We are the proposing the classification of vanishing gastroschisis...
  49. Feldkamp M, Carey J, Sadler T. Development of gastroschisis: review of hypotheses, a novel hypothesis, and implications for research. Am J Med Genet A. 2007;143A:639-52 pubmed
    b>Gastroschisis, a ventral body wall defect, is a continuing challenge and concern to researchers, clinicians, and epidemiologists seeking to identify its cause(s) and pathogenesis...
  50. Lam P, Torfs C. Interaction between maternal smoking and malnutrition in infant risk of gastroschisis. Birth Defects Res A Clin Mol Teratol. 2006;76:182-6 pubmed
    b>Gastroschisis is a severe birth defect characterized by a tear in the infant's abdominal wall. Young mothers have the highest risk of having an infant with gastroschisis...
  51. Banieghbal B, Gouws M, Davies M. Respiratory pressure monitoring as an indirect method of intra-abdominal pressure measurement in gastroschisis closure. Eur J Pediatr Surg. 2006;16:79-83 pubmed
    Abdominal compartment syndrome (ACS) is a rare but potentially fatal complication of gastroschisis closure. The liberal use of a staged reduction technique has become a well-established method of avoiding this problem...
  52. Vu L, Nobuhara K, Laurent C, Shaw G. Increasing prevalence of gastroschisis: population-based study in California. J Pediatr. 2008;152:807-11 pubmed publisher
    To evaluate time trend of gastroschisis and examine the epidemiological risk factors for gastroschisis.
  53. David A, Tan A, Curry J. Gastroschisis: sonographic diagnosis, associations, management and outcome. Prenat Diagn. 2008;28:633-44 pubmed publisher
    b>Gastroschisis is a defect in the abdominal wall, typically on the right side of a normally inserted umbilical cord through which bowel and other abdominal contents herniate...
  54. Cánovas Conesa A, Gomariz Peñalver V, Sánchez Sauco M, Jaimes Vega D, Ortega García J, Aranda García M, et al. [The association of adherence to a Mediterranean diet during early pregnancy and the risk of gastroschisis in the offspring]. Cir Pediatr. 2013;26:37-43 pubmed
    The aim of this study was to study the association of adherence to the Mediterranean diet in early pregnancy maternal and the offspring's risk of gastroschisis.
  55. Netta D, Wilson R, Visintainer P, Johnson M, Hedrick H, Flake A, et al. Gastroschisis: growth patterns and a proposed prenatal surveillance protocol. Fetal Diagn Ther. 2007;22:352-7 pubmed
    To assess intrauterine growth for fetuses with gastroschisis using retrospective serial ultrasound assessment from fetuses diagnosed prenatally with gastroschisis...
  56. Weinsheimer R, Yanchar N. Impact of maternal substance abuse and smoking on children with gastroschisis. J Pediatr Surg. 2008;43:879-83 pubmed publisher
    Conflicting information exists regarding the effects of maternal substance abuse on gastroschisis. The objectives of this study are to determine if maternal smoking is associated with an increased risk of gastroschisis and whether ..
  57. Garcia L, Brizot M, Liao A, Silva M, Tannuri A, Zugaib M. Bowel dilation as a predictor of adverse outcome in isolated fetal gastroschisis. Prenat Diagn. 2010;30:964-9 pubmed publisher
    This study was designed to evaluate bowel diameter as a predictor of adverse outcome in isolated fetal gastroschisis.
  58. Abdullah F, Arnold M, Nabaweesi R, Fischer A, Colombani P, Anderson K, et al. Gastroschisis in the United States 1988-2003: analysis and risk categorization of 4344 patients. J Perinatol. 2007;27:50-5 pubmed
    b>Gastroschisis is a rare congenital abdominal wall defect through which intraabdominal organs herniate and it requires surgical management soon after birth...
  59. Gelas T, Gorduza D, Devonec S, Gaucherand P, Downham E, Claris O, et al. Scheduled preterm delivery for gastroschisis improves postoperative outcome. Pediatr Surg Int. 2008;24:1023-9 pubmed publisher
    ..that careful antenatal monitoring, scheduled preterm delivery and immediate abdominal wall closure may reduce gastroschisis morbidity...
  60. Forrester M, Merz R. Comparison of trends in gastroschisis and prenatal illicit drug use rates. J Toxicol Environ Health A. 2006;69:1253-9 pubmed
    b>Gastroschisis rates have been increasing over time, and gastroschisis risk is elevated in women of young maternal age. Similar patterns were reported for prenatal illicit drug use in Hawaii...
  61. Danzer E, Layne M, Auber F, Shegu S, Kreiger P, Radu A, et al. Gastroschisis in mice lacking aortic carboxypeptidase-like protein is associated with a defect in neuromuscular development of the eviscerated intestine. Pediatr Res. 2010;68:23-8 pubmed publisher
    Mice lacking aortic carboxypeptidase-like protein (ACLP) exhibit a gastroschisis (GS) like abdominal wall defect...
  62. Phillips J, Raval M, Redden C, Weiner T. Gastroschisis, atresia, dysmotility: surgical treatment strategies for a distinct clinical entity. J Pediatr Surg. 2008;43:2208-12 pubmed publisher
    Intestinal atresia (IA) occurs in 10% to 20% of infants born with gastroschisis (GS)...
  63. Ajayi F, Carroll P, Shellhaas C, Foy P, Corbitt R, Osawe O, et al. Ultrasound prediction of growth abnormalities in fetuses with gastroschisis. J Matern Fetal Neonatal Med. 2011;24:489-92 pubmed publisher
    We seek to determine whether (1) mean abdominal circumference (AC) of fetuses with gastroschisis is smaller than published normative values, (2) diagnosis of AC ? 2...
  64. Wilson M, Carroll M, Braun S, Walsh W, Pietsch J, Bennett K. Is preterm delivery indicated in fetuses with gastroschisis and antenatally detected bowel dilation?. Fetal Diagn Ther. 2012;32:262-6 pubmed publisher
    ..to the controversy surrounding diagnostic ultrasound evaluations and elective preterm delivery of fetuses with gastroschisis, we sought to calculate the predictive value of bowel dilation in fetuses with gastroschisis and evaluate the ..
  65. Banyard D, Ramones T, Phillips S, Leys C, Rauth T, Yang E. Method to our madness: an 18-year retrospective analysis on gastroschisis closure. J Pediatr Surg. 2010;45:579-84 pubmed publisher
    ..We retrospectively compared clinical outcomes of neonates having aPR to those having RS placement to determine the impact of routine silo use and silo duration on gastroschisis care.
  66. Waller S, Paul K, Peterson S, Hitti J. Agricultural-related chemical exposures, season of conception, and risk of gastroschisis in Washington State. Am J Obstet Gynecol. 2010;202:241.e1-6 pubmed publisher
    We sought to determine if periconceptional exposure to agrichemicals was associated with the development of gastroschisis.
  67. Kunz S, Tieder J, Whitlock K, Jackson J, Avansino J. Primary fascial closure versus staged closure with silo in patients with gastroschisis: a meta-analysis. J Pediatr Surg. 2013;48:845-57 pubmed publisher
    b>Gastroschisis is the most common congenital abdominal wall defect. Despite advances in the surgical closure of gastroschisis, consensus is lacking as to which method results in the best patient outcomes...
  68. Root E, Meyer R, Emch M. Socioeconomic context and gastroschisis: exploring associations at various geographic scales. Soc Sci Med. 2011;72:625-33 pubmed publisher
    This study examines associations between area-level socioeconomic factors and the birth defect gastroschisis in order to further our understanding of the etiology of this condition...
  69. Stevenson R, Rogers R, Chandler J, Gauderer M, Hunter A. Escape of the yolk sac: a hypothesis to explain the embryogenesis of gastroschisis. Clin Genet. 2009;75:326-33 pubmed publisher
    b>Gastroschisis is a significant birth defect that in many countries has shown an increased prevalence in recent decades, and the change has affected primarily younger mothers...
  70. Baird R, Puligandla P, Skarsgard E, Laberge J. Infectious complications in the management of gastroschisis. Pediatr Surg Int. 2012;28:399-404 pubmed publisher
    Neonates with gastroschisis make up an increasing proportion of prolonged surgical NICU admissions...
  71. Jager L, Heij H. Factors determining outcome in gastroschisis: clinical experience over 18 years. Pediatr Surg Int. 2007;23:731-6 pubmed
    Although the survival in gastroschisis has improved to more than 85%, serious morbidity with consequent long hospital stay is still very common...
  72. Feldkamp M, Carey J, Pimentel R, Krikov S, Botto L. Is gastroschisis truly a sporadic defect?: familial cases of gastroschisis in Utah, 1997 to 2008. Birth Defects Res A Clin Mol Teratol. 2011;91:873-8 pubmed publisher
    b>Gastroschisis remains an epidemiologic and pathogenetic dilemma, with genetics not thought to play a significant role in its etiology...
  73. Boutros J, Regier M, Skarsgard E. Is timing everything? The influence of gestational age, birth weight, route, and intent of delivery on outcome in gastroschisis. J Pediatr Surg. 2009;44:912-7 pubmed publisher
    Optimal perinatal treatment in gastroschisis remains uncertain. We sought to determine the effect of gestational age (GA), birth weight (BW), and intended and actual route of delivery on outcomes in gastroschisis.
  74. Torfs C, Christianson R, Iovannisci D, Shaw G, Lammer E. Selected gene polymorphisms and their interaction with maternal smoking, as risk factors for gastroschisis. Birth Defects Res A Clin Mol Teratol. 2006;76:723-30 pubmed
    b>Gastroschisis is a severe birth defect in which the infant is born with a portion of the intestines extruding through a small tear in the abdominal wall, usually to the right of the umbilical cord...
  75. Frolov P, Alali J, Klein M. Clinical risk factors for gastroschisis and omphalocele in humans: a review of the literature. Pediatr Surg Int. 2010;26:1135-48 pubmed publisher
    b>Gastroschisis and omphalocele are usually considered together since they are both congenital abdominal wall defects, and yet their anatomy, embryogenesis, and clinical presentation and problems are quite different...
  76. Tannuri A, Sbragia L, Tannuri U, Silva L, Leal A, Schmidt A, et al. Evolution of critically ill patients with gastroschisis from three tertiary centers. Clinics (Sao Paulo). 2011;66:17-20 pubmed
    OBJECTIVES AND INTRODUCTION: Gastroschisis is a congenital abdominal wall defect with increasing occurrence worldwide over the past 20-30 years...
  77. Tsai M, Huang H, Chu S, Yang P, Lien R. Clinical features of newborns with gastroschisis and outcomes of different initial interventions: primary closure versus staged repair. Pediatr neonatol. 2010;51:320-5 pubmed publisher
    b>Gastroschisis requires surgical management soon after birth...
  78. Maramreddy H, Fisher J, Slim M, Lagamma E, Parvez B. Delivery of gastroschisis patients before 37 weeks of gestation is associated with increased morbidities. J Pediatr Surg. 2009;44:1360-6 pubmed publisher
    Despite advances in the care of neonates with gastroschisis, patients present with significant morbidities...
  79. South A, Marshall D, Bose C, Laughon M. Growth and neurodevelopment at 16 to 24 months of age for infants born with gastroschisis. J Perinatol. 2008;28:702-6 pubmed publisher
    To examine growth, neurodevelopment and morbidity in infants with gastroschisis.
  80. Siega Riz A, Herring A, Olshan A, Smith J, Moore C. The joint effects of maternal prepregnancy body mass index and age on the risk of gastroschisis. Paediatr Perinat Epidemiol. 2009;23:51-7 pubmed publisher
    Young maternal age has been associated with an increased risk of gastroschisis, while high maternal weight status has been associated with a decreased risk...
  81. Mills J, Lin Y, MacNab Y, Skarsgard E. Perinatal predictors of outcome in gastroschisis. J Perinatol. 2010;30:809-13 pubmed publisher
    To identify perinatal risk variables predictive of outcome in gastroschisis.
  82. Ortega García J, Martin M, Brea Lamas A, De Paco Matallana C, Ruiz Jimenez J, Soldin O. [Integrating the environmental clinic history into prenatal counseling and health care in gastroschisis: 2 case reports]. An Pediatr (Barc). 2010;72:215-9 pubmed publisher
    b>Gastroschisis is a malformation with an unknown aetiology, likely involving genetic and environmental risk factors (RF)...
  83. Brockmann K, Backes H, Auber B, Kriebel T, Stellmer F, Zoll B. Overlap of Moebius and oromandibular limb hypogenesis syndrome with gastroschisis and pulmonary hypoplasia. Am J Med Genet A. 2009;149A:2832-7 pubmed publisher
    ..In this report we describe a girl with gastroschisis and pulmonary hypoplasia in addition to features of Moebius syndrome comprising hypoplasia of the tongue and ..
  84. Salemi J, Pierre M, Tanner J, Kornosky J, Hauser K, Kirby R, et al. Maternal nativity as a risk factor for gastroschisis: a population-based study. Birth Defects Res A Clin Mol Teratol. 2009;85:890-6 pubmed publisher
    The prevalence of gastroschisis is increasing in many parts of the world, although the etiology is largely unexplained. Young maternal age has been the only consistently identified, strong risk factor...