myoglobinuria

Summary

Summary: The presence of MYOGLOBIN in URINE usually as a result of rhabdomyolysis.

Top Publications

  1. Bagley W, Yang H, Shah K. Rhabdomyolysis. Intern Emerg Med. 2007;2:210-8 pubmed
    ..Irrespective of the cause of rhabdomyolysis the mortality rate may still be as high as 8%. This is a comprehensive review of the pathophysiology, diagnosis, complications and treatment options for rhabdomyolysis...
  2. Galvez R, Stacy J, Howley A. Exertional rhabdomyolysis in seven division-1 swimming athletes. Clin J Sport Med. 2008;18:366-8 pubmed publisher
  3. Merlini L, Gooding R, Lochmuller H, Müller Felber W, Walter M, Angelicheva D, et al. Genetic identity of Marinesco-Sjögren/myoglobinuria and CCFDN syndromes. Neurology. 2002;58:231-6 pubmed
    ..Gypsy families with Marinesco-Sjögren syndrome (MSS), demyelinating neuropathy, and recurrent episodes of myoglobinuria in five of the six affected subjects...
  4. Tein I, De Vivo D, Hale D, Clarke J, Zinman H, Laxer R, et al. Short-chain L-3-hydroxyacyl-CoA dehydrogenase deficiency in muscle: a new cause for recurrent myoglobinuria and encephalopathy. Ann Neurol. 1991;30:415-9 pubmed
    ..short-chain L-3-hydroxyacyl-coenzyme A (CoA) dehydrogenase deficiency resulting in juvenile-onset recurrent myoglobinuria, hypoketotic hypoglycemic encephalopathy, and hypertrophic/dilatative cardiomyopathy...
  5. Zeharia A, Shaag A, Houtkooper R, Hindi T, de Lonlay P, Erez G, et al. Mutations in LPIN1 cause recurrent acute myoglobinuria in childhood. Am J Hum Genet. 2008;83:489-94 pubmed publisher
    Recurrent episodes of life-threatening myoglobinuria in childhood are caused by inborn errors of glycogenolysis, mitochondrial fatty acid beta-oxidation, and oxidative phosphorylation...
  6. David W. Myoglobinuria. Neurol Clin. 2000;18:215-43 pubmed
    b>Myoglobinuria refers to an abnormal pathologic state in which an excessive amount of myoglobin is found in the urine, imparting a cola-like hue, usually in association with myonecrosis and a clinical picture of weakness, myalgias, and ..
  7. Lee H, Ota Setlik A, Xu H, D Agati V, Jacobson M, Emala C. A3 adenosine receptor knockout mice are protected against ischemia- and myoglobinuria-induced renal failure. Am J Physiol Renal Physiol. 2003;284:F267-73 pubmed
    ..125 mg/kg IB-MECA) exacerbated renal I/R injury in mice. Mice lacking A(3) ARs or blocking A(3) ARs in wild-type mice resulted in significant renal protection from ischemic or myoglobinuric renal failure...
  8. Lindner A, Zierz S. [Rhabdomyolysis and myoglobinuria]. Nervenarzt. 2003;74:505-15 pubmed
    ..into the circulation, most notably creatine phosphokinase (CK) and myoglobin, and is frequently accompanied by myoglobinuria. Therefore, the term myoglobinuria is often used interchangeably with the term rhabdomyolysis...
  9. Taroni F, Verderio E, Dworzak F, Willems P, Cavadini P, DiDonato S. Identification of a common mutation in the carnitine palmitoyltransferase II gene in familial recurrent myoglobinuria patients. Nat Genet. 1993;4:314-20 pubmed
    ..The Ser113Leu mutation is the most frequent cause of CPT II deficiency. The mutation can be detected easily by restriction analysis enabling molecular diagnosis of most patients and identification of heterozygous carriers...

More Information

Publications95

  1. Mongini T, Doriguzzi C, Bosone I, Chiadò Piat L, Hoffman E, Palmucci L. Alpha-sarcoglycan deficiency featuring exercise intolerance and myoglobinuria. Neuropediatrics. 2002;33:109-11 pubmed
    ..In the following years the patient developed exercise intolerance and myoglobinuria. Immunohistochemistry showed marked reduction of alpha-sarcoglycan, confirmed by Western blotting...
  2. Minetti C, Garavaglia B, Bado M, Invernizzi F, Bruno C, Rimoldi M, et al. Very-long-chain acyl-coenzyme A dehydrogenase deficiency in a child with recurrent myoglobinuria. Neuromuscul Disord. 1998;8:3-6 pubmed
    A 9-year-old boy had recurrent episodes of myoglobinuria and normal urinary organic acid profile...
  3. Zager R. Rhabdomyolysis and myohemoglobinuric acute renal failure. Kidney Int. 1996;49:314-26 pubmed
  4. Naka T, Jones D, Baldwin I, Fealy N, Bates S, Goehl H, et al. Myoglobin clearance by super high-flux hemofiltration in a case of severe rhabdomyolysis: a case report. Crit Care. 2005;9:R90-5 pubmed
    ..To test the ability of a novel super high-flux (SHF) membrane with a larger pore size to clear myoglobin from serum...
  5. Shirakawa K, Takahashi Y, Miyajima H. Intronic mutation in the PGK1 gene may cause recurrent myoglobinuria by aberrant splicing. Neurology. 2006;66:925-7 pubmed
    A 33-year-old man with mental retardation and recurrent myoglobinuria demonstrated a deficiency in the phosphoglycerate kinase 1 (PGK1) activity of his muscles and erythrocytes...
  6. Oh S, Park K, Ryan H, Danon M, Lu J, Naini A, et al. Exercise-induced cramp, myoglobinuria, and tubular aggregates in phosphoglycerate mutase deficiency. Muscle Nerve. 2006;34:572-6 pubmed
    ..phosphoglycerate mutase (PGAM) deficiency was associated with the triad of exercise-induced cramps, recurrent myoglobinuria, and tubular aggregates in the muscle biopsy...
  7. Grossman R, Hamilton R, Morse B, Penn A, Goldberg M. Nontraumatic rhabdomyolysis and acute renal failure. N Engl J Med. 1974;291:807-11 pubmed
  8. Fujii H, Kanno H, Hirono A, Shiomura T, Miwa S. A single amino acid substitution (157 Gly----Val) in a phosphoglycerate kinase variant (PGK Shizuoka) associated with chronic hemolysis and myoglobinuria. Blood. 1992;79:1582-5 pubmed
    ..in a new phosphoglycerate kinase (PGK) variant, PGK Shizuoka, associated with chronic hemolysis and myoglobinuria. PGK Shizuoka had an extremely low enzyme activity with normal kinetic properties and normal electrophoretic ..
  9. Ishibashi H, Ohta T, Hosaka M, Sugimoto I, Kawanishi J, Yamada T. Gluteal compartment syndrome after abdominal aortic aneurysm repair. Vasa. 2004;33:89-91 pubmed
    ..The patient recovered without any discomfort to the buttock or intermittent claudication. To our knowledge this is the first documented case of gluteal compartment syndrome after the repair of an abdominal aortic aneurysm. ..
  10. Apeland T, Danielsen T, Staal E, Asberg A, Thorsen I, Dalsrud T, et al. Risk factors for exertional rhabdomyolysis with renal stress. BMJ Open Sport Exerc Med. 2017;3:e000241 pubmed publisher
    ..The purpose of this study was to determine important risk factors for the development of exertional rhabdomyolysis in a temperate climate and to study the renal effects of myoglobinuria.
  11. Chander V, Singh D, Chopra K. Reversal of experimental myoglobinuric acute renal failure in rats by quercetin, a bioflavonoid. Pharmacology. 2005;73:49-56 pubmed
    ..Based on these results, this study confirms the role of oxidative stress and demonstrates the renoprotective potential of quercetin in this rhabdomyolysis-mimicking model. ..
  12. Deschauer M, Wieser T, Zierz S. Muscle carnitine palmitoyltransferase II deficiency: clinical and molecular genetic features and diagnostic aspects. Arch Neurol. 2005;62:37-41 pubmed
    ..deficiency is an autosomal recessive disorder of fatty acid oxidation characterized by attacks of myalgia and myoglobinuria. This review summarizes the clinical features of this disease, analyzing data of 28 patients with ..
  13. Honda S, Kawasaki T, Kamitani T, Kiyota K. Rhabdomyolysis after High Intensity Resistance Training. Intern Med. 2017;56:1175-1178 pubmed publisher
    ..His symptoms and laboratory findings gradually improved with the intravenous administration of saline and no complications (including electrolyte imbalance and acute renal failure) developed. ..
  14. Bruno C, Minetti C, Shanske S, Morreale G, Bado M, Cordone G, et al. Combined defects of muscle phosphofructokinase and AMP deaminase in a child with myoglobinuria. Neurology. 1998;50:296-8 pubmed
    A 14-year-old boy with exercise-related myalgia and cramps had several episodes of myoglobinuria since early childhood. An episode at 2 years of age caused acute renal failure...
  15. Turbat Herrera E. Myoglobinuric acute renal failure associated with cocaine use. Ultrastruct Pathol. 1994;18:127-31 pubmed
    ..Insights into cocaine metabolism, adverse effects, and interaction with alcohol, diagnostic considerations, and mechanisms involved in renal damage are addressed. ..
  16. Sato H, Sugie H, Sugie Y, Ito M, Tsurui S, Igarashi Y, et al. [Muscle carnitine contents in severely handicapped children with acute myoglobinuria]. No To Hattatsu. 1993;25:233-6 pubmed
    Muscle carnitine was measured in 3 severely handicapped children with acute myoglobinuria. Muscle total carnitine levels were 9.6 +/- 3.0 nmol/mg non collagen protein (m +/- SD, control 15.7 +/- 2.8, n = 19), and free 6.5 +/- 3...
  17. Tolouian R, Wild D, Lashkari M, Najafi I. Oral alkalinizing solution as a potential prophylaxis against myoglobinuric acute renal failure: preliminary data from healthy volunteers. Nephrol Dial Transplant. 2005;20:1228-31 pubmed
    ..v. hydration is not possible. A dose of 10 ml/kg/h may be the correct amount to induce alkaline diuresis within the first 12 h after crush injuries. The use of OAS for this purpose should be evaluated further. ..
  18. Evenepoel P. Acute toxic renal failure. Best Pract Res Clin Anaesthesiol. 2004;18:37-52 pubmed
  19. van der Kolk H. [Equine atypical myopathy]. Tijdschr Diergeneeskd. 2006;131:934 pubmed
  20. Gurgel Giannetti J, Nogales Gadea G, van der Linden H, Bellard T, Brasileiro Filho G, Giannetti A, et al. Clinical and molecular characterization of McArdle's disease in Brazilian patients. Neuromolecular Med. 2013;15:470-5 pubmed publisher
    ..Other mutations previously reported in European patients were also found in the patients in this study, which was expected considering the European ancestry of the Brazilian population. ..
  21. Wieser T, Deschauer M, Olek K, Hermann T, Zierz S. Carnitine palmitoyltransferase II deficiency: molecular and biochemical analysis of 32 patients. Neurology. 2003;60:1351-3 pubmed
    ..Using modeling techniques, a structure could be identified anchoring the protein in the membrane. Only one of the five mutations (Y479F) is located within this region. ..
  22. Yong K, Tan B, Low C. Severe falciparum malaria with dengue coinfection complicated by rhabdomyolysis and acute kidney injury: an unusual case with myoglobinemia, myoglobinuria but normal serum creatine kinase. BMC Infect Dis. 2012;12:364 pubmed publisher
    Acute kidney injury (AKI) is a complication of severe malaria, and rhabdomyolysis with myoglobinuria is an uncommon cause...
  23. Yanazume S, Yanazume Y, Iwamoto I, Tsuji T, Yoshinaga M, Douchi T. Severe leg compartment syndrome associated with dorsal lithotomy position during radical hysterectomy. J Obstet Gynaecol Res. 2006;32:610-2 pubmed
    ..We must always consider the potential risk of this life-threatening complication when patients are placed in the dorsal lithotomy position for a prolonged period during extended surgery using intermittent external compression. ..
  24. Meola M, Samoni S, Petrucci I, Ronco C. Clinical Scenarios in Acute Kidney Injury: Parenchymal Acute Kidney Injury-Tubulo-Interstitial Diseases. Contrib Nephrol. 2016;188:39-47 pubmed publisher
    ..It may be due to a direct kidney injury, such as sepsis, drugs, toxins, contrast media, hemoglobinuria and myoglobinuria, or it may be the consequence of a prolonged systemic ischemic injury...
  25. Clarke J, Nolan R. Resident's corner. Answer to case of the month #93. Exercise-induced rhabdomyolysis. Can Assoc Radiol J. 2003;54:310-2 pubmed
  26. Authier F, Gherardi R. [Muscular complications of human immunodeficiency virus (HIV) infection in the era of effective anti-retroviral therapy]. Rev Neurol (Paris). 2006;162:71-81 pubmed
    ..These features are described in the present review. ..
  27. Papalia T, Bonofiglio R, De Napoli N. [Myoglobinuric acute renal failure secondary to convulsion]. G Ital Nefrol. 2003;20:306-7 pubmed
    ..Myoglobinuric acute renal failure secondary to convulsion. ..
  28. Imataka G, Yamanouchi H. [Coenzyme Q10 deficiency]. Nihon Rinsho. 2002;60 Suppl 4:462-5 pubmed
  29. Aydogdu N, Atmaca G, Yalcin O, Batcioglu K, Kaymak K. Effects of caffeic acid phenethyl ester on glycerol-induced acute renal failure in rats. Clin Exp Pharmacol Physiol. 2004;31:575-9 pubmed
    ..5. We suggest that the effect of CAPE in decreasing NO concentrations may further increase the renal ischaemia in this model. Thus, CAPE may have a worsening rather than beneficial effect under these conditions in this model of ARF. ..
  30. Kutlu A, Kara C, Cetinkaya S. Rhabdomyolysis without detectable myoglobulinuria due to severe hypophosphatemia in diabetic ketoacidosis. Pediatr Emerg Care. 2011;27:537-8 pubmed publisher
    ..The patient was treated without dialysis and was cured after a polyuria period of 2 months after the oliguric period. ..
  31. Vasudevan A, Uthamalingam S, Kumar S, Tamarin F, Brensilver J. Colchicine-induced rhabdomyolysis: the whole is greater than the sum of its parts!. Am J Med. 2003;115:249 pubmed
  32. Perkoff G. Alcoholic myopathy. Annu Rev Med. 1971;22:125-32 pubmed
  33. Chochola M, Lubanda J, Skalicka L, Varejka P, Horejs J, Prskavec T, et al. [Bilateral leg compartment syndrome due to severe myonecrosis caused by inappropriate use of simvastatin]. J Mal Vasc. 2008;33:229-33 pubmed publisher
    ..patient underwent urgent renal replacement therapy with continuous hemodialysis for acute renal failure due to myoglobinuria. After this complex treatment, the patient was discharged...
  34. Braseth N, Allison E, Gough J. Exertional rhabdomyolysis in a body builder abusing anabolic androgenic steroids. Eur J Emerg Med. 2001;8:155-7 pubmed
    Rhabdomyolysis, or acute skeletal muscle destruction, may be accompanied by myoglobinaemia, myoglobinuria, and an elevated serum creatine kinase level. This disorder has many potential causes...
  35. Maghsoudi H, Adyani Y, Ahmadian N. Electrical and lightning injuries. J Burn Care Res. 2007;28:255-61 pubmed
    ..Electrical burn injuries continue to be a serious problem of modern society. Climbing power poles is the most common mechanism for high-voltage injury. Special consideration is required to prevent this type of injury in our region...
  36. Plotnikov E, Silachev D, Chupyrkina A, Danshina M, Jankauskas S, Morosanova M, et al. New-generation Skulachev ions exhibiting nephroprotective and neuroprotective properties. Biochemistry (Mosc). 2010;75:145-50 pubmed
    ..effect of this compound was demonstrated in a model of focal brain ischemia, rat kidney ischemia/reperfusion, myoglobinuria (rhabdomyolysis, or crush syndrome), and pyelonephritis...
  37. Pastorello E, Cao M, Trevisan C. Atypical onset in a series of 122 cases with FacioScapuloHumeral Muscular Dystrophy. Clin Neurol Neurosurg. 2012;114:230-4 pubmed publisher
    ..non-FSHD-related syndromes: a 42-year-old woman presented with infantile epilepsy and a 41-year-old man with myoglobinuria. In the latter patient, DNA analysis detected a 4q35 deletion associated to an heterozygous CAPN3 mutation...
  38. Khan F. Rhabdomyolysis: a review of the literature. Neth J Med. 2009;67:272-83 pubmed
  39. Carol M. Hydroxycut weight loss dietary supplements: a contributing factor in the development of exertional rhabdomyolysis in three U.S. Army soldiers. Mil Med. 2013;178:e1039-42 pubmed publisher
  40. Veerapandiyan A, Shashi V, Jiang Y, Gallentine W, Schoch K, Smith E. Pseudometabolic presentation of dystrophinopathy due to a missense mutation. Muscle Nerve. 2010;42:975-9 pubmed publisher
    ..In this retrospective chart review, we report 3 unrelated boys with exertional myalgia, muscle stiffness, myoglobinuria, and normal neurological examination due to an identical point mutation in the DMD gene: a hemizygous T-to-C ..
  41. Palmiere C, Mangin P. Hyperthermia and postmortem biochemical investigations. Int J Legal Med. 2013;127:93-102 pubmed publisher
    ..The aim of this article is to present a review of the medicolegal literature pertaining to the postmortem biochemical investigations that are associated with heat-related deaths...
  42. Zhang L, Ding J, Wang Y, Zhang W, Deng X, Chen J. MRI quantitative study and pathologic analysis of crush injury in rabbit hind limb muscles. J Surg Res. 2011;167:e357-63 pubmed publisher
    ..To explore the value of quantitative magnetic resonance imaging (i.e., T2 map technique) in the diagnosis of crush injury in rabbit hind limb muscles...
  43. Boni R, Rabitti P. [Spinning-induced rhabdomyolysis: importance of MRI for patient's outcome. A case report]. Reumatismo. 2011;63:44-8 pubmed
    ..This observation could be useful to understand the timing for exercise resumption without any risk for the patient...
  44. Kasap B, Soylu A, Turkmen M, Kavukcu S. An adolescent girl with Meyer-Betz syndrome. Clin Rheumatol. 2006;25:904-6 pubmed
    ..She was advised to avoid strenuous physical exertion and had an uneventful outcome for the last 5 months. We reported the clinical course and follow-up of an adolescent girl with Meyer-Betz syndrome...
  45. Santhosh G, Joseph W, Thomas M. Strychnine poisoning. J Assoc Physicians India. 2003;51:739-40 pubmed
  46. Spiekerkoetter U, Bennett M, Ben Zeev B, Strauss A, Tein I. Peripheral neuropathy, episodic myoglobinuria, and respiratory failure in deficiency of the mitochondrial trifunctional protein. Muscle Nerve. 2004;29:66-72 pubmed
    ..Therefore, this disorder must be considered in the differential diagnosis of progressive peripheral neuropathy with or without episodic myoglobinuria.
  47. Getachew E, Prayson R. Pathologic quiz case: a man with exertion-induced cramps and myoglobinuria. McArdle disease (glycogenosis type V or myophosphorylase deficiency). Arch Pathol Lab Med. 2003;127:1227-8 pubmed
  48. Vissing C, Duno M, Olesen J, Rafiq J, Risom L, Christensen E, et al. Recurrent myoglobinuria and deranged acylcarnitines due to a mutation in the mtDNA MT-CO2 gene. Neurology. 2013;80:1908-10 pubmed publisher
    ..In contrast, exercise-induced rhabdomyolysis and myoglobinuria occur rarely...
  49. Fisk D, Bradley S. Rhabdomyolysis induced by Salmonella enterica serovar Typhi bacteraemia. Clin Microbiol Infect. 2004;10:595-7 pubmed
    ..Prompt diagnosis and treatment resulted in a good outcome. Salmonella infection should be considered by clinicians as a possibility in the differential diagnosis of rhabdomyolysis...
  50. Vlahovic P, Cvetkovic T, Savic V, Stefanovic V. Dietary curcumin does not protect kidney in glycerol-induced acute renal failure. Food Chem Toxicol. 2007;45:1777-82 pubmed
    ..The results obtained in this study provided additional evidence that despite its limited antioxidant activity curcumin did not protect kidney in myoglobinuric model of ARF...
  51. Taniyama S, Sagara T, Nishio S, Kuroki R, Asakawa M, Noguchi T, et al. [Survey of food poisoning incidents in Japan due to ingestion of marine boxfish and their toxicity]. Shokuhin Eiseigaku Zasshi. 2009;50:270-7 pubmed
    ..2%, 5.6%). From the above results, we conclude that O. cubicus and L. diaphana inhabiting the coast of Japan sometimes contain toxic substance(s), which can sporadically cause food poisonings very similar to parrotfish poisoning...
  52. Corti S, Bordoni A, Ronchi D, Musumeci O, Aguennouz M, Toscano A, et al. Clinical features and new molecular findings in Carnitine Palmitoyltransferase II (CPT II) deficiency. J Neurol Sci. 2008;266:97-103 pubmed
    ..most common inherited disorder of lipid metabolism characterized in its adult form by attacks of myalgia and myoglobinuria. We analyzed a cohort of 22 CPT II-deficient patients (representing 20 independent probands) to correlate ..
  53. Aboumousa A, Hoogendijk J, Charlton R, Barresi R, Herrmann R, Voit T, et al. Caveolinopathy--new mutations and additional symptoms. Neuromuscul Disord. 2008;18:572-8 pubmed publisher
    ..One of the patients reported episodes of myoglobinuria and another one episodes of hypoglycaemia...
  54. Traub B, Lane M, Traub J. Exercise-Induced Acute Bilateral Upper-Arm Compartment Syndrome. Case Rep Emerg Med. 2017;2017:9454782 pubmed publisher
    ..Decompressive fasciotomy was performed followed by an intensive care unit (ICU) stay for associated myoglobinuria secondary to rhabdomyolysis...
  55. Dupond J, de Wazieres B, Monnier G, Closs F, Desmurs H. [Silent exercise-induced enzymatic myopathies at rest in adults. A cause of confusion with fibromyalgia]. Presse Med. 1992;21:974-8 pubmed
    ..These diseases are usually recognized when exercise-induced myalgias, myoglobinuria and raised creatinine kinase (CK) levels are present...
  56. Spiegel R, Gomez E, Akman H, Krishna S, Horovitz Y, DiMauro S. Myopathic form of phosphoglycerate kinase (PGK) deficiency: a new case and pathogenic considerations. Neuromuscul Disord. 2009;19:207-11 pubmed publisher
    We describe an 18-year-old man with muscle cramps and recurrent exertional myoglobinuria, without hemolytic anemia or brain dysfunction...
  57. Ustundag S, Sen S, Yalcin O, Ciftci S, Demirkan B, Ture M. L-Carnitine ameliorates glycerol-induced myoglobinuric acute renal failure in rats. Ren Fail. 2009;31:124-33 pubmed publisher
    ..L-carnitine, possibly via its antioxidant properties, ameliorates glycerol-induced myoglobinuric kidney injury...
  58. Ossai N, Hour B, Szerlip H. Border-crossers' nephropathy: the risk of coming to America. Ren Fail. 2013;35:483-6 pubmed publisher
    ..We have coined the term "border crossers' nephropathy" for this disorder. This is a serious problem that has both political and economic consequences on both sides of the border...
  59. Premru V, Kovac J, Buturovic Ponikvar J, Ponikvar R. High cut-off membrane hemodiafiltration in myoglobinuric acute renal failure: a case series. Ther Apher Dial. 2011;15:287-91 pubmed publisher
    ..Rapid redistribution from the extracellular fluid and sustained myoglobin release were suggested by the high rebound observed. Elimination of myoglobin within the body was shown in our study to occur slowly during the period of anuria...
  60. Aasly J, van Diggelen O, Boer A, Brønstad G. Phosphoglycerate kinase deficiency in two brothers with McArdle-like clinical symptoms. Eur J Neurol. 2000;7:111-3 pubmed
    ..After these episodes they noticed that the urine was dark brown, indicating rhabdomyolysis and myoglobinuria. The neurological examinations were without remarks...
  61. Costantino S, De Galasso L. [Non-traumatic rhabdomyolysis: clinical and laboratory diagnosis, assessment of renal complications]. Clin Ter. 2002;153:77 pubmed
  62. Garrood P, Eagle M, Jardine P, Bushby K, Straub V. Myoglobinuria in boys with Duchenne muscular dystrophy on corticosteroid therapy. Neuromuscul Disord. 2008;18:71-3 pubmed
    b>Myoglobinuria is a recognised complication of Duchenne muscular dystrophy (DMD), but has only once been reported in ambulant boys on corticosteroid therapy [Dubowitz V, Kinali M, Main M, Mercuri E, Muntoni F...
  63. Okafor V, Akpa F. Acute renal failure due to myoglobulinuria in a patient struck by lightning. Nephrology (Carlton). 2006;11:478-9 pubmed
  64. Chanard J, Kleinknecht D, Dreyfus J, Fardeau M, Kaplan M. [Myoglobinuria caused by McArdle's disease complicated by anuric acute renal insufficiency]. Arch Fr Pediatr. 1972;29:433 pubmed
  65. Shelton G. Rhabdomyolysis, myoglobinuria, and necrotizing myopathies. Vet Clin North Am Small Anim Pract. 2004;34:1469-82 pubmed
  66. Chander V, Chopra K. Molsidomine, a nitric oxide donor and L-arginine protects against rhabdomyolysis-induced myoglobinuric acute renal failure. Biochim Biophys Acta. 2005;1723:208-14 pubmed
    ..The animals treated with L-NAME along with glycerol further worsened the renal damage observed with glycerol. As a result, our results indicate that molsidomine and L-arginine may have beneficial effects in myoglobinuric ARF...
  67. Schliamser J, Avramovitch N, Karkabi B, Flugelman M, Militianu A, Lewis B. Rhabdomyolysis induced by repeated internal cardioverter defibrillator discharges. Pacing Clin Electrophysiol. 2002;25:516-7 pubmed
  68. Suzuki H, Hirayama Y, Hirano S, Takahashi R, Nonaka I, Sugie H, et al. [Carnitine palmitoyltransferase deficiency in a patient with severe psychomotor retardation]. No To Hattatsu. 1991;23:93-7 pubmed
    ..CPT deficiency is usually found in young healthy persons. This is the first case report of CPT deficiency which presented severe psychomotor retardation since neonatal period...
  69. Savic V, Vlahovic P, Djordjevic V, Mitic Zlatkovic M, Avramovic V, Stefanovic V. Nephroprotective effects of pentoxifylline in experimental myoglobinuric acute renal failure. Pathol Biol (Paris). 2002;50:599-607 pubmed
    ..This study in glycerol-induced acute renal failure showed a marked renal morphologic and functional protection by pentoxifylline...
  70. Guzman N, Podoll A, Bell C, Finkel K. Myoglobin removal using high-volume high-flux hemofiltration in patients with oliguric acute kidney injury. Blood Purif. 2013;36:107-11 pubmed publisher
    ..Therefore, we examined myoglobin removal in a series of 11 patients with oliguric AKI treated with high-volume hemofiltration...
  71. Motoyoshi N, Komatsu T, Moizumi Y, Tabayashi K. Atypical paraplegia after aortic intramural hematoma. J Thorac Cardiovasc Surg. 2003;125:409-10 pubmed
  72. Tasic V, Avramoski V, Korneti P. Mild rhabdomyolysis in a child with fever and "hematuria". Pediatr Nephrol. 2003;18:462-4 pubmed
    ..b>Myoglobinuria was demonstrated by a "blood"-positive dipstick in the absence of red blood cells in the urinary ..
  73. Torres Villalobos G, Kimura E, Mosqueda J, García García E, Dominguez Cherit G, Herrera M. Pressure-induced rhabdomyolysis after bariatric surgery. Obes Surg. 2003;13:297-301 pubmed
    ..We report 3 superobese patients who developed rhabdomyolysis after bariatric surgery. This complication was attributed to direct and prolonged pressure of the bed against the dorsal and gluteal muscles...
  74. Bando T, Fujimura M, Noda Y, Ohta G, Matsuda T. Rhabdomyolysis following status asthmaticus. Respiration. 1996;63:309-11 pubmed
    ..with aminophylline, salbutamol and corticosteroid, transiently elevated serum creatine phosphokinase and myoglobinuria were present. Rhabdomyolysis has rarely been reported in cases of bronchial asthma...
  75. Lin A, Lin C, Wang T, Leu J. Rhabdomyolysis in 119 students after repetitive exercise. Br J Sports Med. 2005;39:e3 pubmed
    ..This is the report of 119 cases in high school students who exercised vigorously (120 push ups in five minutes) in cold weather. Most of them developed muscle pain and dark urine within two to four days of the exercise...
  76. Vora S, Corash L, Engel W, Durham S, Seaman C, Piomelli S. The molecular mechanism of the inherited phosphofructokinase deficiency associated with hemolysis and myopathy. Blood. 1980;55:629-35 pubmed
    ..The propositus, a 31-yr-old male, suffered from muscle weakness and myoglobinuria on exertion. He showed mild erythrocytosis despite laboratory evidence of hemolysis...
  77. Ozaki H, Ishikawa C, Ishii T, Toyoda A, Murano T, Miyashita Y, et al. Clearance rates of cerivastatin metabolites in a patient with cerivastatin-induced rhabdomyolysis. J Clin Pharm Ther. 2005;30:189-92 pubmed
    ..These results suggest that the slowed clearance of cerivastatin in this patient might have been compounded by cytochrome P450, 2C8 dysfunction...
  78. Rehman J, Boglia J, Chughtai B, Sukkarieh T, Khan S, Lewis R, et al. High body mass index in muscular patients and flank position are risk factors for rhabdomyolysis: case report after laparoscopic live-donor nephrectomy. J Endourol. 2006;20:646-50 pubmed
    ..Postoperatively, it most likely is secondary to surgical positioning and patient muscle mass. We report a case after laparoscopic live-donor nephrectomy...
  79. Cortes Franco S, Pacheco Abreu E, Martel D, Millán Corada A, Garcia Conde M, Spreafico M, et al. [Bilateral lower limb compartment syndrome after lumbar schwannoma surgery in genupectoral position]. Neurocirugia (Astur). 2007;18:56-9 pubmed
    ..Overweigth and long time surgery could be important predisposing factors. Early diagnosis and treatment are mandatory to prevent permanent neurological deficits and other possible complications...
  80. Banasik M, Kuzniar J, Kusztal M, Porazko T, Weyde W, Klinger M. Myoglobinuria caused by exertional rhabdomyolysis misdiagnosed as psychiatric illness. Med Sci Monit. 2008;14:CS1-4 pubmed
    ..During injury, intracellular muscle contents are released into the plasma. The consequences may cause hypovolemia, electrolyte abnormalities, compartment syndrome, or even acute renal failure and dialysis...
  81. Elke B, Ludin S, Fehr T. [Macro- and microhematuria in the adult]. Praxis (Bern 1994). 2008;97:755-61; quiz 761-2 pubmed
  82. Blackford M, Fitzgibbon J, Reed M. Assessment of serum creatine kinase among adolescent patients following jimsonweed (Datura stramonium) and moonflower (Datura inoxia) ingestions: a review of 11 cases. Clin Toxicol (Phila). 2010;48:431-4 pubmed publisher
    ..To our knowledge, only one case report describes rhabdomyolysis in association with DS or DI ingestion...
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    ..Myoglobin levels above 15?mg/L were most significantly related to the development of AKI and the need for HD. Blood myoglobin could serve as a valuable early predictor and marker of rhabdomyolysis and Mb-AKI. ..
  84. Jauchem J. Deaths in custody: are some due to electronic control devices (including TASER devices) or excited delirium?. J Forensic Leg Med. 2010;17:1-7 pubmed publisher
    ..On the basis of current available information, factors other than ECDs themselves may be more important when death occurs after the use of ECDs...
  85. Toscano A, Musumeci O. Tarui disease and distal glycogenoses: clinical and genetic update. Acta Myol. 2007;26:105-7 pubmed
    ..with prominent clinical symptoms characterized by muscle cramps, exercise intolerance, rhabdomyolysis and myoglobinuria, often associated with haemolytic anaemia and hyperuricaemia...
  86. Fu C. [Treatment for crush syndrome of extremities with antioxidants]. Zhongguo Gu Shang. 2008;21:109-10 pubmed
    ..To study the clinical therapeutic effect of antioxidants assistant treatment of extremities crush syndrome (CS)in order to find new therapy...