contracture

Summary

Summary: Prolonged shortening of the muscle or other soft tissue around a joint, preventing movement of the joint.

Top Publications

  1. Barnes A, Duncan G, Weis M, Paton W, Cabral W, Mertz E, et al. Kuskokwim syndrome, a recessive congenital contracture disorder, extends the phenotype of FKBP10 mutations. Hum Mutat. 2013;34:1279-88 pubmed publisher
    ..Kuskokwim syndrome (KS) is an autosomal recessive congenital contracture disorder found among Yup'ik Eskimos...
  2. Malhotra S, Pandyan A, Rosewilliam S, Roffe C, Hermens H. Spasticity and contractures at the wrist after stroke: time course of development and their association with functional recovery of the upper limb. Clin Rehabil. 2011;25:184-91 pubmed publisher
    ..To investigate the time course of development of spasticity and contractures at the wrist after stroke and to explore if these are associated with upper limb functional recovery...
  3. Malhotra S, Rosewilliam S, Hermens H, Roffe C, Jones P, Pandyan A. A randomized controlled trial of surface neuromuscular electrical stimulation applied early after acute stroke: effects on wrist pain, spasticity and contractures. Clin Rehabil. 2013;27:579-90 pubmed publisher
    ..To investigate effects of surface neuromuscular electrical stimulation applied early after stroke to the wrist and finger extensor muscles on upper limb pain, spasticity and contractures in patients with no functional arm movement...
  4. Kulahci Y, Sever C, Uygur F, Oksuz S, Sahin C, Duman H. Pre-expanded pedicled thoracodorsal artery perforator flap for postburn axillary contracture reconstruction. Microsurgery. 2011;31:26-31 pubmed publisher
    ..In this clinical study, we used pre-expanded pedicled thoracodorsal artery (TDA) perforator flaps for release of postburn contracture of the axillary region.
  5. Patel A, DiGiovanni B. Association between plantar fasciitis and isolated contracture of the gastrocnemius. Foot Ankle Int. 2011;32:5-8 pubmed publisher
    ..This limitation can arise from either an isolated contracture of the gastrocnemius or from a contracture of the gastrocnemius-soleus complex...
  6. Smith L, Lee K, Ward S, Chambers H, Lieber R. Hamstring contractures in children with spastic cerebral palsy result from a stiffer extracellular matrix and increased in vivo sarcomere length. J Physiol. 2011;589:2625-39 pubmed publisher
    ..Secondary to the UMNl esion,which causes spasticity, is a pathological response by muscle - namely, contracture. However, the elements within muscle that increase passive mechanical stiffness, and therefore result in ..
  7. Weihl C. Another VCP interactor: NF is enough. J Clin Invest. 2011;121:4627-30 pubmed publisher
    ..Thus, aberrant interactions between VCP and NF1 may explain the dementia phenotype and cognitive delay observed in patients with IBMPFD and neurofibromatosis type 1...
  8. Sabatelli P, Palma E, Angelin A, Squarzoni S, Urciuolo A, Pellegrini C, et al. Critical evaluation of the use of cell cultures for inclusion in clinical trials of patients affected by collagen VI myopathies. J Cell Physiol. 2012;227:2927-35 pubmed publisher
  9. Dancey A, Nassimizadeh A, Levick P. Capsular contracture - What are the risk factors? A 14 year series of 1400 consecutive augmentations. J Plast Reconstr Aesthet Surg. 2012;65:213-8 pubmed publisher
    ..We specifically examined the incidence of capsular contracture and the possible causative factors. Follow up ranged from 1 to 16 years...

Scientific Experts

More Information

Publications62

  1. Atilla B, Caglar O, Pekmezci M, Buyukasik Y, Tokgozoglu A, Alpaslan M. Pre-operative flexion contracture determines the functional outcome of haemophilic arthropathy treated with total knee arthroplasty. Haemophilia. 2012;18:358-63 pubmed publisher
    ..outcome of TKA in haemophilic patients with specific attention to final range of motion and residual flexion contracture of the joint. Twenty-one consecutive patients were retrospectively reviewed...
  2. Wang H, Shih Y, Chen C, Chao H, Lee M, Hsueh Y. Valosin-containing protein and neurofibromin interact to regulate dendritic spine density. J Clin Invest. 2011;121:4820-37 pubmed publisher
    ..The data presented here demonstrate that there is a link between IBMPFD and NF1 and indicate a role for VCP in synapse formation...
  3. Goudie S, Deakin A, Ahmad A, Maheshwari R, Picard F. Flexion contracture following primary total knee arthroplasty: risk factors and outcomes. Orthopedics. 2011;34:e855-9 pubmed publisher
    ..Fixed flexion contracture is a recognized complication of TKA that reduces ROM and is a source of morbidity for patients...
  4. Kwah L, Herbert R, Harvey L, Diong J, Clarke J, Martin J, et al. Passive mechanical properties of gastrocnemius muscles of people with ankle contracture after stroke. Arch Phys Med Rehabil. 2012;93:1185-90 pubmed publisher
    To investigate the mechanisms of contracture after stroke by comparing passive mechanical properties of gastrocnemius muscle-tendon units, muscle fascicles, and tendons in people with ankle contracture after stroke with control ..
  5. Lustig S, Scholes C, Stegeman T, Oussedik S, Coolican M, Parker D. Sagittal placement of the femoral component in total knee arthroplasty predicts knee flexion contracture at one-year follow-up. Int Orthop. 2012;36:1835-9 pubmed publisher
    Flexion contracture has been shown to impair function and reduce satisfaction following total knee arthroplasty (TKA). The aim of this study was to identify modifiable intra-operative variables that predict post-TKA knee extension.
  6. Rieger U, Mesina J, Kalbermatten D, Haug M, Frey H, Pico R, et al. Bacterial biofilms and capsular contracture in patients with breast implants. Br J Surg. 2013;100:768-74 pubmed publisher
    It has been hypothesized that bacterial biofilms on breast implants may cause chronic inflammation leading to capsular contracture. The association between bacterial biofilms of removed implants and capsular contracture was investigated.
  7. Bönnemann C. The collagen VI-related myopathies Ullrich congenital muscular dystrophy and Bethlem myopathy. Handb Clin Neurol. 2011;101:81-96 pubmed publisher
    ..A genetic spectrum is emerging, with BM being caused mostly by dominantly acting mutations, although rarely recessive inheritance of BM is also possible, whereas both dominantly as well as recessively acting mutations underlie UCMD. ..
  8. Monument M, Hart D, Befus A, Salo P, Zhang M, Hildebrand K. The mast cell stabilizer ketotifen reduces joint capsule fibrosis in a rabbit model of post-traumatic joint contractures. Inflamm Res. 2012;61:285-92 pubmed publisher
    ..Using a rabbit model of post-traumatic joint contractures, we investigated whether treatment with a mast cell stabilizer after joint injury would lessen the molecular manifestations of joint capsule fibrosis...
  9. Clavet H, Hebert P, Fergusson D, Doucette S, Trudel G. Joint contracture following prolonged stay in the intensive care unit. CMAJ. 2008;178:691-7 pubmed publisher
    Prolonged immobility during a critical illness may predispose patients to the development of joint contracture. We sought to document the incidence of, the risk factors for and the reversibility of joint contractures among patients who ..
  10. van der Sluijs J, van Ouwerkerk W, de Gast A, Nollet F, Winters H, Wuisman P. Treatment of internal rotation contracture of the shoulder in obstetric brachial plexus lesions by subscapular tendon lengthening and open reduction: early results and complications. J Pediatr Orthop B. 2004;13:218-24 pubmed
    In this prospective study of 19 consecutive children, the operative treatment of internal rotation contracture of the shoulder in obstetric brachial plexus lesions by subscapular tendon lengthening and open reduction of the humeral head ..
  11. Arangio G, Rogman A, Reed J. Hindfoot alignment valgus moment arm increases in adult flatfoot with Achilles tendon contracture. Foot Ankle Int. 2009;30:1078-82 pubmed publisher
    Adult acquired flatfoot is often associated with Achilles tendon contracture and may be associated with isolated spring ligament insufficiency without Achilles tendon contracture...
  12. John M, Willis F, Portillo A. Dynamic splinting for runner's toe: a case report with gait analysis. J Am Podiatr Med Assoc. 2009;99:367-70 pubmed
    We present a case report of runner's hallux limitus and the effect of dynamic splinting in reducing contracture as measured by gait analysis...
  13. Grella E, Grella R, Siniscalco D, Fuccio C, Rossi F, De Novellis V, et al. Modification of cysteinyl leukotriene receptors expression in capsular contracture: follow-up study and definitive results. Ann Plast Surg. 2009;63:206-8 pubmed publisher
    Periprosthetic capsular contracture represents a specific iatrogenic phenomenon with different side effects...
  14. Lindenhovius A, Linzel D, Doornberg J, Ring D, Jupiter J. Comparison of elbow contracture release in elbows with and without heterotopic ossification restricting motion. J Shoulder Elbow Surg. 2007;16:621-5 pubmed
    ..restricting elbow motion (but not complete bony ankylosis) after elbow trauma with 21 patients with capsular contracture alone to test the hypothesis that HO is associated with diminished motion after release...
  15. Smeulders M, Kreulen M, Hage J, Huijing P, van der Horst C. Overstretching of sarcomeres may not cause cerebral palsy muscle contracture. J Orthop Res. 2004;22:1331-5 pubmed
    To answer the question whether the muscle contracture in patients with cerebral palsy is caused by overstretching of in-series sarcomeres we studied the active and passive force-length relationship of the flexor carpi ulnaris muscle (FCU)..
  16. Chandra Paul A, Swapan K, Spronk C, Niemeijer R, Spauwen P. Postburn contracture treatment: a healthcare project in Bangladesh. Burns. 2008;34:181-4 pubmed
    ..Future actions should be directed to the training of surgeons and the development of specialized hospitals to demonstrate social as well as political commitment to health care programs...
  17. Park J, Cho C, Choi J, Lee S, Kang C. Radial nerve palsy after arthroscopic anterior capsular release for degenerative elbow contracture. Arthroscopy. 2007;23:1360.e1-3 pubmed
    ..after arthroscopic anterior capsular release using a ball-tipped electrocautery device on a degenerative elbow contracture. We supposed that the electrocautery device caused transiently thermal injury of the radial nerve despite ..
  18. Moseley A, Herbert R, Nightingale E, Taylor D, Evans T, Robertson G, et al. Passive stretching does not enhance outcomes in patients with plantarflexion contracture after cast immobilization for ankle fracture: a randomized controlled trial. Arch Phys Med Rehabil. 2005;86:1118-26 pubmed
    To compare the efficacy of short- and long-duration passive stretches with a control treatment for the management of plantarflexion contracture after cast immobilization for ankle fracture.
  19. Noda S, Iwakawa M, Ohta T, Iwata M, Yang M, Goto M, et al. Inter-strain variance in late phase of erythematous reaction or leg contracture after local irradiation among three strains of mice. Cancer Detect Prev. 2005;29:376-82 pubmed
    ..To gain insights into inter-strain differences in radiosensitivity...
  20. Benediktsson K, Perbeck L. Capsular contracture around saline-filled and textured subcutaneously-placed implants in irradiated and non-irradiated breast cancer patients: five years of monitoring of a prospective trial. J Plast Reconstr Aesthet Surg. 2006;59:27-34 pubmed
    ..The primary aim of this prospective study was to determine the frequency of capsular contracture in both irradiated and non-irradiated breasts after this operation...
  21. Hildebrand K, Zhang M, Hart D. Joint capsule matrix turnover in a rabbit model of chronic joint contractures: Correlation with human contractures. J Orthop Res. 2006;24:1036-43 pubmed
    ..for collagen types I, II, and III, and MMP-1 and -13 were significantly increased in the joint capsules of the contracture knees in all groups when compared to normal and contralateral limb joint capsules...
  22. Lannin N, Cusick A, McCluskey A, Herbert R. Effects of splinting on wrist contracture after stroke: a randomized controlled trial. Stroke. 2007;38:111-6 pubmed
    Splints are commonly applied to the wrist and hand to prevent and treat contracture after stroke. However, there have been few randomized trials of this intervention...
  23. Hildebrand K, Sutherland C, Zhang M. Rabbit knee model of post-traumatic joint contractures: the long-term natural history of motion loss and myofibroblasts. J Orthop Res. 2004;22:313-20 pubmed
    ..The average flexion contracture of the experimental knees in the 0-week and 8-week remobilization groups (38 degrees and 33 degrees, ..
  24. Singer B, Dunne J, Singer K, Jegasothy G, Allison G. Non-surgical management of ankle contracture following acquired brain injury. Disabil Rehabil. 2004;26:335-45 pubmed
    The purpose of this study was to document the outcome of non-surgical management of equinovarus ankle contracture in a cohort of patients with acquired brain injury admitted to a specialist Neurosurgical Rehabilitation Unit.
  25. Carmichael K, Maxwell S, Calhoun J. Recurrence rates of burn contracture ankle equinus and other foot deformities in children treated with Ilizarov fixation. J Pediatr Orthop. 2005;25:523-8 pubmed
    ..In young children, the possibility of having additional surgeries, including repeat Ilizarov procedures, should be discussed. Even older children should expect additional surgeries to prevent recurrent deformities...
  26. Usuba M, Miyanaga Y, Miyakawa S, Maeshima T, Shirasaki Y. Effect of heat in increasing the range of knee motion after the development of a joint contracture: an experiment with an animal model. Arch Phys Med Rehabil. 2006;87:247-53 pubmed
    To compare the effects of 2 different heat modalities, infrared and ultrasonic therapy, on a knee flexion contracture.
  27. Moulder E, Marsh C. Soft tissue knee contracture of the knee due to melorheostosis, treated by total knee arthroplasty. Knee. 2006;13:395-6 pubmed
    Melorheostosis is a rare condition which can cause soft tissue joint contractures. We present a case of melorheostosis causing disabling knee joint contracture, treated successfully by total knee arthroplasty.
  28. Bellemans J, Vandenneucker H, Victor J, Vanlauwe J. Flexion contracture in total knee arthroplasty. Clin Orthop Relat Res. 2006;452:78-82 pubmed
    We retrospectively evaluated a surgical algorithm for treating flexion contracture in total knee arthroplasty using a prospectively collected database of 2898 knees...
  29. Gnass I, Bartoszek G, Thiesemann R, Meyer G. [Joint contractures in older age. A systematic literature review]. Z Gerontol Geriatr. 2010;43:147-57 pubmed publisher
    ..Contractures lead to additional nursing demands. In Germany, contracture risk assessment and prevention have been recently defined as a quality indicator of nursing home care that ..
  30. Robinson W, Smith R, Aung O, Ada L. No difference between wearing a night splint and standing on a tilt table in preventing ankle contracture early after stroke: a randomised trial. Aust J Physiother. 2008;54:33-8 pubmed
    Is wearing a night splint as effective as standing on a tilt table in preventing ankle dorsiflexion contracture and promoting the ability to stand up early after stroke?
  31. Nobuta S, Sato K, Kasama F, Hatori M, Itoi E. Open elbow arthrolysis for post-traumatic elbow contracture. Ups J Med Sci. 2008;113:95-102 pubmed
    Post-traumatic contracture is a common complication after elbow trauma. If conservative therapy fails to restore adequate elbow motion, arthrolysis is indicated...
  32. Al Ahaideb A, Drosdowech D, Pichora D. Fractional flexor tendon lengthening for advanced metacarpophalangeal flexion contracture in rheumatoid hands. J Hand Surg Am. 2006;31:1690-3 pubmed
    ..of rheumatoid patients who have minimal ulnar drift but a severe fixed metacarpophalangeal joint flexion contracture for whom conventional metacarpophalangeal joint arthroplasty alone was insufficient to correct the deformity...
  33. Takaesu Miyagi S, Sakai H, Shiroma T, Hayakawa K, Funakoshi Y, Sawaguchi S. Ocular findings of Beals syndrome. Jpn J Ophthalmol. 2004;48:470-4 pubmed
    ..In this report of two Okinawan patients with Beals syndrome and accompanying ocular complications, the symptoms of Beals syndrome and Marfan syndrome are compared. The etiology of these two syndromes is considered in relation to fibrillin...
  34. Hagiwara Y, Ando A, Chimoto E, Saijo Y, Ohmori Matsuda K, Itoi E. Changes of articular cartilage after immobilization in a rat knee contracture model. J Orthop Res. 2009;27:236-42 pubmed publisher
    ..Although we do not know the reversibility of these changes of articular cartilage, early mobilization is preferable to avoid these cartilage changes...
  35. Patrick E, Ada L. The Tardieu Scale differentiates contracture from spasticity whereas the Ashworth Scale is confounded by it. Clin Rehabil. 2006;20:173-82 pubmed
    ..To compare the Tardieu Scale as a clinical measure of spasticity after stroke with the Ashworth Scale...
  36. Xue F, Liao X, Li C, Xu Y, Yang Q, Liu Y, et al. Clinical experience of airway management and tracheal intubation under general anesthesia in patients with scar contracture of the neck. Chin Med J (Engl). 2008;121:989-97 pubmed
    Because patients with scar contracture of the neck are at a high risk of loss of the airway control after anesthesia induction, awake intubation is usually recommended...
  37. de Jong L, Nieuwboer A, Aufdemkampe G. Contracture preventive positioning of the hemiplegic arm in subacute stroke patients: a pilot randomized controlled trial. Clin Rehabil. 2006;20:656-67 pubmed
    To investigate the effectiveness of a contracture preventive positioning procedure for the hemiplegic arm in subacute stroke patients in addition to conventional physio- and occupational therapy.
  38. Ritter M, Lutgring J, Davis K, Berend M, Pierson J, Meneghini R. The role of flexion contracture on outcomes in primary total knee arthroplasty. J Arthroplasty. 2007;22:1092-6 pubmed
    This study examined the role that flexion contracture plays in postoperative outcomes after total knee arthroplasty using a retrospective database review...
  39. D Andrea F, Nicoletti G, Grella E, Grella R, Siniscalco D, Fuccio C, et al. Modification of cysteinyl leukotriene receptor expression in capsular contracture: Preliminary results. Ann Plast Surg. 2007;58:212-4 pubmed
    ..The pathogenesis of capsular contracture is still unclear, but most reports indicate a multifactorial explanation...
  40. Ishii H, Choudhuri R, Mathias A, Sowers A, Flanders K, Cook J, et al. Halofuginone mediated protection against radiation-induced leg contracture. Int J Oncol. 2009;35:315-9 pubmed
    ..The latter, TSP1, a co-activator of TGF-beta may serve as a suitable biomarker for monitoring the efficacy of halofuginone should it be evaluated in a clinical setting for protection against radiation-induced fibrosis...
  41. Roukis T, Schade V. Percutaneous flexor tenotomy for treatment of neuropathic toe ulceration secondary to toe contracture in persons with diabetes: a systematic review. J Foot Ankle Surg. 2009;48:684-9 pubmed publisher
    Percutaneous flexor tenotomy has been proposed for treatment of neuropathic toe ulcerations secondary to toe contracture in persons with diabetes who have failed ongoing local wound care measures due to the perceived safety and efficacy...
  42. Pearl M, Edgerton B, Kazimiroff P, Burchette R, Wong K. Arthroscopic release and latissimus dorsi transfer for shoulder internal rotation contractures and glenohumeral deformity secondary to brachial plexus birth palsy. J Bone Joint Surg Am. 2006;88:564-74 pubmed
    ..We report the results for the first thirty-three children followed for a minimum of two years after such treatment...
  43. Garrott H, Walland M, O Day J. Recurrent posterior capsular opacification and capsulorhexis contracture after cataract surgery in myotonic dystrophy. Clin Exp Ophthalmol. 2004;32:653-5 pubmed
    ..Less well known are the phenomena of recurrent posterior capsule opacification and capsulorhexis contracture post cataract surgery...
  44. Westbom L, Hagglund G, Nordmark E. Cerebral palsy in a total population of 4-11 year olds in southern Sweden. Prevalence and distribution according to different CP classification systems. BMC Pediatr. 2007;7:41 pubmed
    ..The aim of this study was to investigate the prevalence of cerebral palsy (CP) as well as to characterize the CP population, its participation in a secondary prevention programme (CPUP) and to validate the CPUP database...
  45. Lee Y, Chiu A, Huang J. Comprehensive study of bladder neck contracture after transurethral resection of prostate. Urology. 2005;65:498-503; discussion 503 pubmed
    ..and retrospective study was done to review comprehensively the incidence of, severity of, and risk factors for bladder neck contracture (BNC) in patients with benign prostatic hyperplasia who underwent transurethral surgery.
  46. Scuderi G, Kochhar T. Management of flexion contracture in total knee arthroplasty. J Arthroplasty. 2007;22:20-4 pubmed
    Flexion contracture is a common deformity encountered during total knee arthroplasty. Most deformities are mild and can be passively corrected at the time of surgery...
  47. Pontén E, Gantelius S, Lieber R. Intraoperative muscle measurements reveal a relationship between contracture formation and muscle remodeling. Muscle Nerve. 2007;36:47-54 pubmed
    Children with cerebral palsy often have spasticity of both the extensors and flexors, but how and why a flexion contracture of the wrist will develop during growth is not thoroughly understood...
  48. Abe S, Kohyama K, Yokoyama H, Matsuda S, Terashima Y, Nakagawa N, et al. Total knee arthroplasty for rheumatoid knee with bilateral, severe flexion contracture: report of three cases. Mod Rheumatol. 2008;18:499-506 pubmed publisher
    The treatment of patients with severe flexion contracture of the rheumatoid knee, deprived of ambulation for long periods of time, is challenging...
  49. Wagner L, Capezuti E, Brush B, Clevenger C, Boltz M, Renz S. Contractures in frail nursing home residents. Geriatr Nurs. 2008;29:259-66 pubmed publisher
    ..Almost two thirds of the participants had at least 1 contracture, with the most common locations being the shoulder and knee...
  50. Sackley C, Brittle N, Patel S, Ellins J, Scott M, Wright C, et al. The prevalence of joint contractures, pressure sores, painful shoulder, other pain, falls, and depression in the year after a severely disabling stroke. Stroke. 2008;39:3329-34 pubmed publisher
    ..This inception cohort study sought to investigate the prevalence of immobility-related complications during the first year after severely disabling stroke in relation to functional independence and place of residence...
  51. Yim H, Cho Y, Seo C, Lee B, Ko J, Kim D, et al. The use of AlloDerm on major burn patients: AlloDerm prevents post-burn joint contracture. Burns. 2010;36:322-8 pubmed publisher
    In efforts to prevent and reduce joint contracture and scar formation after burn, we used the acellular human dermis (AlloDerm) as a dermal replacement in the acute stage...
  52. Donaldson O, Pearson D, Reynolds R, Bhatia R. The association between intraoperative correction of Dupuytren's disease and residual postoperative contracture. J Hand Surg Eur Vol. 2010;35:220-3 pubmed publisher
    The purpose of this study was to determine whether preoperative contracture and the amount of intraoperative correction can be used to predict the postoperative outcome of fasciectomy for Dupuytren's disease...
  53. Kozin S, Boardman M, Chafetz R, Williams G, Hanlon A. Arthroscopic treatment of internal rotation contracture and glenohumeral dysplasia in children with brachial plexus birth palsy. J Shoulder Elbow Surg. 2010;19:102-10 pubmed publisher
    ..The purpose of the study was to assess the ability of arthroscopic anterior release, +/- tendon transfers to maintain shoulder joint alignment in children with brachial plexus palsy, and to assess their outcome after arthroscopic reduction...