substance induced psychoses

Summary

Summary: Psychotic organic mental disorders resulting from the toxic effect of drugs and chemicals or other harmful substance.

Top Publications

  1. Pomarol Clotet E, Honey G, Murray G, Corlett P, Absalom A, Lee M, et al. Psychological effects of ketamine in healthy volunteers. Phenomenological study. Br J Psychiatry. 2006;189:173-9 pubmed
    ..The psychosis-inducing effect of ketamine is important evidence supporting the glutamate hypothesis of schizophrenia. However, the symptoms the drug produces have not been described systematically...
  2. Stone J, Erlandsson K, Arstad E, Squassante L, Teneggi V, Bressan R, et al. Relationship between ketamine-induced psychotic symptoms and NMDA receptor occupancy: a [(123)I]CNS-1261 SPET study. Psychopharmacology (Berl). 2008;197:401-8 pubmed publisher
    ..Ketamine induces effects resembling both positive and negative psychotic symptoms of schizophrenia. These are thought to arise through its action as an uncompetitive antagonist of the N-methyl-D-aspartate (NMDA) receptor...
  3. Stone J, Pilowsky L. Psychopathological consequences of ketamine. Br J Psychiatry. 2006;189:565-6 pubmed
  4. D Souza D, Perry E, MacDougall L, Ammerman Y, Cooper T, Wu Y, et al. The psychotomimetic effects of intravenous delta-9-tetrahydrocannabinol in healthy individuals: implications for psychosis. Neuropsychopharmacology. 2004;29:1558-72 pubmed
    ..These data warrant further study of whether brain cannabinoid receptor function contributes to the pathophysiology of psychotic disorders...
  5. Koethe D, Gerth C, Neatby M, Haensel A, Thies M, Schneider U, et al. Disturbances of visual information processing in early states of psychosis and experimental delta-9-tetrahydrocannabinol altered states of consciousness. Schizophr Res. 2006;88:142-50 pubmed
  6. Ujike H, Sato M. Clinical features of sensitization to methamphetamine observed in patients with methamphetamine dependence and psychosis. Ann N Y Acad Sci. 2004;1025:279-87 pubmed
    ..Molecular findings using animal sensitization models may facilitate a better understanding of, and open the way for innovative therapies for, METH psychosis and also chronic schizophrenia...
  7. Gouzoulis Mayfrank E, Heekeren K, Neukirch A, Stoll M, Stock C, Daumann J, et al. Inhibition of return in the human 5HT2A agonist and NMDA antagonist model of psychosis. Neuropsychopharmacology. 2006;31:431-41 pubmed
    ..Blunted IOR may underlie or predispose to different psychotic manifestations, but particularly to those with prominent positive symptoms...
  8. Geyer M, Vollenweider F. Serotonin research: contributions to understanding psychoses. Trends Pharmacol Sci. 2008;29:445-53 pubmed publisher
    ..This review summarizes experimental assessments of the serotonergic hallucinogen model psychosis in relation to the serotonin hypothesis of schizophrenia...
  9. Witton J, Murray R. [Reefer madness revisited: cannabis and psychosis]. Rev Bras Psiquiatr. 2004;26:2-3 pubmed

More Information

Publications62

  1. Corlett P, Honey G, Aitken M, Dickinson A, Shanks D, Absalom A, et al. Frontal responses during learning predict vulnerability to the psychotogenic effects of ketamine: linking cognition, brain activity, and psychosis. Arch Gen Psychiatry. 2006;63:611-21 pubmed
    ..Establishing a neurobiological account of delusion formation that links cognitive processes, brain activity, and symptoms is important to furthering our understanding of psychosis...
  2. Kukoyi O, Carney C. Curses, madness, and mefloquine. Psychosomatics. 2003;44:339-41 pubmed
  3. Vollenweider F, Leenders K, Scharfetter C, Antonini A, Maguire P, Missimer J, et al. Metabolic hyperfrontality and psychopathology in the ketamine model of psychosis using positron emission tomography (PET) and [18F]fluorodeoxyglucose (FDG). Eur Neuropsychopharmacol. 1997;7:9-24 pubmed
  4. Breier A, Adler C, Weisenfeld N, Su T, Elman I, Picken L, et al. Effects of NMDA antagonism on striatal dopamine release in healthy subjects: application of a novel PET approach. Synapse. 1998;29:142-7 pubmed
    ..The implications of this brain imaging method for studies of schizophrenia and the mechanism of action of antipsychotic drugs are discussed...
  5. Vollenweider F, Vontobel P, Oye I, Hell D, Leenders K. Effects of (S)-ketamine on striatal dopamine: a [11C]raclopride PET study of a model psychosis in humans. J Psychiatr Res. 2000;34:35-43 pubmed
    ..These results provide evidence that the glutamatergic NMDA receptor may contribute to psychotic symptom formation via modulation of the DA system...
  6. Morio A, Ujike H, Nomura A, Tanaka Y, Morita Y, Otani K, et al. No association between CART (cocaine- and amphetamine-regulated transcript) gene and methamphetamine dependence. Ann N Y Acad Sci. 2006;1074:411-7 pubmed
    ..The present findings suggest that the CART gene may not play a pivotal role in the development of METH dependence and psychosis, at least in a Japanese population...
  7. Ozer F, Meral H, Aydin B, Hanoglu L, Aydemir T, Oral T. Electroconvulsive therapy in drug-induced psychiatric states and neuroleptic malignant syndrome. J ECT. 2005;21:125-7 pubmed
    ..Later, the patient had two episodes of depressive and psychotic symptoms, which were again successfully treated with the ECT. We suggest that ECT might be an effective and life-saving therapy in patients with severe, drug-resistant NMS...
  8. Dan A, Thygesen T, Pinholt E. Corticosteroid administration in oral and orthognathic surgery: a systematic review of the literature and meta-analysis. J Oral Maxillofac Surg. 2010;68:2207-20 pubmed publisher
    ..This study evaluated the effect of corticosteroid (CS) administration on edema, analgesia, and neuroregeneration in conjunction with surgical dental extraction, orthognathic surgery, and the risk of developing side effects...
  9. Bowers M, Kantrowitz J. Elevated plasma dopamine metabolites in cannabis psychosis. Am J Psychiatry. 2007;164:1615-6 pubmed
  10. Mathias S, Lubman D, Hides L. Substance-induced psychosis: a diagnostic conundrum. J Clin Psychiatry. 2008;69:358-67 pubmed
    ..To critically examine the DSM-IV-TR criteria for substance-induced psychotic disorder (SIPD)...
  11. Carroll A, McSherry B, Wood D, Yannoulidis S. Drug-associated psychoses and criminal responsibility. Behav Sci Law. 2008;26:633-53 pubmed publisher
    ..This article analyses legal, policy, and expert witness perspectives relating to liberal, conservative, and intermediate approaches to this problematic area of jurisprudence...
  12. Ezaki N, Nakamura K, Sekine Y, Thanseem I, Anitha A, Iwata Y, et al. Short allele of 5-HTTLPR as a risk factor for the development of psychosis in Japanese methamphetamine abusers. Ann N Y Acad Sci. 2008;1139:49-56 pubmed publisher
    ..Thus, we suggest a possible role for the 5-HTTLPR polymorphism in MAP psychosis...
  13. Thapa R, Biswas B. Childhood mefloquine-induced mania and psychosis: a case report. J Child Neurol. 2009;24:1008-9 pubmed publisher
    ..A positive history of intake of the offending drug with careful exclusion of other etiologies usually clinches the diagnosis...
  14. Krystal J, Perry E, Gueorguieva R, Belger A, Madonick S, Abi Dargham A, et al. Comparative and interactive human psychopharmacologic effects of ketamine and amphetamine: implications for glutamatergic and dopaminergic model psychoses and cognitive function. Arch Gen Psychiatry. 2005;62:985-94 pubmed
    ..Studying the comparative and interactive effects of these agents may provide insights into the roles of the glutamate and monoamine systems in psychosis and cognition...
  15. Daumann J, Heekeren K, Neukirch A, Thiel C, Möller Hartmann W, Gouzoulis Mayfrank E. Pharmacological modulation of the neural basis underlying inhibition of return (IOR) in the human 5-HT2A agonist and NMDA antagonist model of psychosis. Psychopharmacology (Berl). 2008;200:573-83 pubmed publisher
    ..Pharmacologic challenges with hallucinogens have been used as models for psychosis...
  16. Gaszner P, Csernus I, Fülöp B, Gaszner G. [Schizoid psychosis during cannabis intake (case report)]. Neuropsychopharmacol Hung. 2004;6:90-2 pubmed
    ..The first two patients become symptom-free on the antipsychotics and during the drug-free period. The third patient, who had cannabis during the psychotic symptoms, still has the schizoid psychosis...
  17. Boly L, Cafaro V, Dyner T. Depressive symptoms predict increased incidence of neuropsychiatric side effects in patients treated with efavirenz. J Acquir Immune Defic Syndr. 2006;42:514-5 pubmed
  18. Miyajima M, Matsumoto T, Ito S. 2C-T-4 intoxication: acute psychosis caused by a designer drug. Psychiatry Clin Neurosci. 2008;62:243 pubmed publisher
  19. Odenwald M, Hinkel H, Schauer E, Schauer M, Elbert T, Neuner F, et al. Use of khat and posttraumatic stress disorder as risk factors for psychotic symptoms: a study of Somali combatants. Soc Sci Med. 2009;69:1040-8 pubmed publisher
    ..However, the proposed causal chain needs to be confirmed in longitudinal studies. Demobilization and reintegration programs in Somalia need to be prepared to deal with complex psychological problems...
  20. Helseth V, Lykke Enger T, Aamo T, Johnsen J. [Drug screening among patients aged 17-40 admitted with psychosis]. Tidsskr Nor Laegeforen. 2005;125:1178-80 pubmed
    ..The purpose of this investigation was to find the prevalence of substance use among younger psychotic inpatients in Norway and to compare patients' self reports with the results of screening for drugs...
  21. Sumnall H, Wagstaff G, Cole J. Self-reported psychopathology in polydrug users. J Psychopharmacol. 2004;18:75-82 pubmed
    ..It remains to be determined at what point adverse effects of drug use begin to interfere with day-to-day life...
  22. Flanders S. Delusions incorporating cannabis use in dually diagnosed patients with a primary psychotic disorder. Aust N Z J Psychiatry. 2007;41:934-6 pubmed
    ..To describe and discuss the implications for treatment of 3 cases of dually diagnosed patients with a primary psychotic disorder who have developed persisting, cannabis-oriented delusional systems...
  23. Karnik N, Joshi S, Paterno C, Shaw R. Subtypes of pediatric delirium: a treatment algorithm. Psychosomatics. 2007;48:253-7 pubmed
    ..This framework provides an algorithm for the treatment of pediatric delirium...
  24. Adams H. Awareness, dreaming or steroid-induced psychosis. Anaesthesia. 2007;62:198 pubmed
  25. Pae C, Marks D, Han C, Patkar A. A case of transient hallucination with ropinirole augmentation antidepressant in a patient with treatment-resistant depression: Is there differential effect of ropinirole dose on developing psychotic symptom?. Prog Neuropsychopharmacol Biol Psychiatry. 2008;32:1087-8 pubmed publisher
  26. Leong G, Leisenring S, Dean M. Commentary: intoxication and settled insanity--unsettled matters. J Am Acad Psychiatry Law. 2007;35:183-7 pubmed
    ..However, the current nosology and knowledge base reveal ambiguity and unresolved questions about the present science related to settled insanity...
  27. Nebeker J, Yarnold P, Soltysik R, Sauer B, Sims S, Samore M, et al. Developing indicators of inpatient adverse drug events through nonlinear analysis using administrative data. Med Care. 2007;45:S81-8 pubmed
    ..Rules based on nonlinear associations among all types of available administrative data may be more accurate...
  28. Ujike H. [Potential genetic predictors for individual vulnerability to substance dependence]. Nihon Shinkei Seishin Yakurigaku Zasshi. 2008;28:11-7 pubmed
    ..Odds ratios of these positive or negative risks ranged from about 0.2 to 15. These findings must be informative for drug dependence rehabilitation programs and psycho-education of substance dependence...
  29. Cooper R. Chloroquine should be used with care in mental health disorders. Indian J Physiol Pharmacol. 2008;52:97-8 pubmed
  30. Ozaki S, Wada K. [A validation of the applicability of the Severity of Dependence Scale (SDS) in a nationwide mental hospital survey on substance-related psychiatric disorders]. Nihon Arukoru Yakubutsu Igakkai Zasshi. 2005;40:126-36 pubmed
  31. Stefan J, Mathew B. Khat chewing: an emerging drug concern in Australia?. Aust N Z J Psychiatry. 2005;39:842-3 pubmed
  32. Mariani J, Hart C. Psychosis associated with modafinil and shift work. Am J Psychiatry. 2005;162:1983 pubmed
  33. Brooks J, Hoblyn J. Secondary mania in older adults. Am J Psychiatry. 2005;162:2033-8 pubmed
  34. Chou K, Fernandez H. Combating psychosis in Parkinson's disease patients: the use of antipsychotic drugs. Expert Opin Investig Drugs. 2006;15:339-49 pubmed
  35. Barkus E, Stirling J, Hopkins R, Lewis S. Cannabis-induced psychosis-like experiences are associated with high schizotypy. Psychopathology. 2006;39:175-8 pubmed
    ..We tested the hypothesis that cannabis use increases the likelihood of psychosis-like experiences in non-clinical participants who scored highly on a measure of schizotypy...
  36. Morrison P, Zois V, McKeown D, Lee T, Holt D, Powell J, et al. The acute effects of synthetic intravenous Delta9-tetrahydrocannabinol on psychosis, mood and cognitive functioning. Psychol Med. 2009;39:1607-16 pubmed publisher
    ..In a study of intravenous (i.v.) synthetic THC in healthy humans, we aimed to study the relationship of the psychotic symptoms induced by THC to the consequent anxiety and neuropsychological impairment...
  37. Ujike H, Katsu T, Okahisa Y, Takaki M, Kodama M, Inada T, et al. Genetic variants of D2 but not D3 or D4 dopamine receptor gene are associated with rapid onset and poor prognosis of methamphetamine psychosis. Prog Neuropsychopharmacol Biol Psychiatry. 2009;33:625-9 pubmed publisher
    ..00037, OR=3.62, 95% CI 2.48-5.28). These findings revealed that genetic variants of DRD2, but not DRD3 or DRD4, confer individual risks for rapid onset, prolonged duration, and spontaneous relapse of methamphetamine psychosis...
  38. Foster H, Hoffer A. The two faces of L-DOPA: benefits and adverse side effects in the treatment of Encephalitis lethargica, Parkinson's disease, multiple sclerosis and amyotrophic lateral sclerosis. Med Hypotheses. 2004;62:177-81 pubmed
    ..A literature review suggests that all three corollaries are probably correct...
  39. Kishi T, Ikeda M, Kitajima T, Yamanouchi Y, Kinoshita Y, Kawashima K, et al. Alpha4 and beta2 subunits of neuronal nicotinic acetylcholine receptor genes are not associated with methamphetamine-use disorder in the Japanese population. Ann N Y Acad Sci. 2008;1139:70-82 pubmed publisher
    ..In conclusion, our results suggest that neither CHRNA4 nor CHRNB2 plays a major role in Japanese METH-use disorder...
  40. Kiangkitiwan B, Doppalapudi A, Fonder M, Solberg K, Bohner B. Levofloxacin-induced delirium with psychotic features. Gen Hosp Psychiatry. 2008;30:381-3 pubmed publisher
    ..To raise awareness of a rare but serious adverse effect of a commonly used medication...
  41. Duggal H, Singh I. Worsening of psychosis or topiramate-induced adverse event?. Gen Hosp Psychiatry. 2004;26:245-7 pubmed
  42. Benson P, Leonards U, Lothian R, St Clair D, Merlo M. Visual scan paths in first-episode schizophrenia and cannabis-induced psychosis. J Psychiatry Neurosci. 2007;32:267-74 pubmed
    ..We used higher-order statistical methods to examine spatiotemporal characteristics of scan paths to determine whether viewing behaviour was distinguishable on a continuum...
  43. Moncrieff J. Does antipsychotic withdrawal provoke psychosis? Review of the literature on rapid onset psychosis (supersensitivity psychosis) and withdrawal-related relapse. Acta Psychiatr Scand. 2006;114:3-13 pubmed
    ..To examine the evidence that discontinuation of long-term antipsychotic medication, including clozapine, may provoke a psychotic episode...
  44. Feix J, Wolber G. Intoxication and settled insanity: a finding of not guilty by reason of insanity. J Am Acad Psychiatry Law. 2007;35:172-82 pubmed
    ..The evaluating clinician must still determine, even when a threshold condition is considered to be present, whether statutory criteria for the insanity defense (for the jurisdiction in which the crime allegedly took place) are met...
  45. Nakamura K, Chen C, Sekine Y, Iwata Y, Anitha A, Loh E, et al. Association analysis of SOD2 variants with methamphetamine psychosis in Japanese and Taiwanese populations. Hum Genet. 2006;120:243-52 pubmed
    ..014 and 0.016, respectively) and in the allelic (P value 0.004 and 0.047, respectively) frequencies. Our results suggest that Ala/Val polymorphism of the SOD2 gene could be associated with the risk of developing methamphetamine psychosis...
  46. Hall W, Degenhardt L, Teesson M. Cannabis use and psychotic disorders: an update. Drug Alcohol Rev. 2004;23:433-43 pubmed
    ..It seems more likely that cannabis use can precipitate schizophrenia in vulnerable individuals. There is also reasonable evidence for the third hypothesis that cannabis use exacerbates psychosis...
  47. Pratt J, Winchester C, Egerton A, Cochran S, Morris B. Modelling prefrontal cortex deficits in schizophrenia: implications for treatment. Br J Pharmacol. 2008;153 Suppl 1:S465-70 pubmed publisher
    ..As such it is likely to be a valuable translational model for understanding the neurobiological mechanisms underlying hypofrontality and for identifying and validating novel drug targets that may restore PFC deficits in schizophrenia...
  48. Schaub M, Rossler W, Stohler R. [Cannabis and psychosis--a review]. Praxis (Bern 1994). 2004;93:997-1002 pubmed
    ..Cannabis use seems to worsen the course of schizophrenia spectrum disorders. Adolescents run a higher risk from using cannabis than older people. They should be strongly advised not to indulge in such behaviour...
  49. Bischoff A. [Childhood schizophrenia. Only every fifth patient was asymptomatic as a child]. MMW Fortschr Med. 2004;146:14 pubmed
  50. Crebbin K, Mitford E, Paxton R, Turkington D. First-episode drug-induced psychosis: a medium term follow up study reveals a high-risk group. Soc Psychiatry Psychiatr Epidemiol. 2009;44:710-5 pubmed publisher
    ..Little is known about first-episode drug-induced psychosis (F19.5)...
  51. Witkowski A, Manabat C, Bourgeois J. Isoniazid-associated psychosis. Gen Hosp Psychiatry. 2007;29:85-6 pubmed
  52. Martin S, Bowden F. Ethambutol toxicity manifesting as acute onset psychosis. Int J STD AIDS. 2007;18:287-8 pubmed
    ..A 40-year-old man with advanced HIV infection and Mycobacterium avium complex infection experienced rapid cognitive decline after commencement of ethambutol, and symptoms fully resolved with cessation...
  53. Lambert M, Conus P, Lubman D, Wade D, Yuen H, Moritz S, et al. The impact of substance use disorders on clinical outcome in 643 patients with first-episode psychosis. Acta Psychiatr Scand. 2005;112:141-8 pubmed
    ..The main aim of the present study was to assess the impact of baseline SUD and course of SUD on remission of positive symptoms...