acquired dyslexia

Summary

Summary: A receptive visual aphasia characterized by the loss of a previously possessed ability to comprehend the meaning or significance of handwritten words, despite intact vision. This condition may be associated with posterior cerebral artery infarction (INFARCTION, POSTERIOR CEREBRAL ARTERY) and other BRAIN DISEASES.

Top Publications

  1. Gaillard R, Naccache L, Pinel P, Clemenceau S, Volle E, Hasboun D, et al. Direct intracranial, FMRI, and lesion evidence for the causal role of left inferotemporal cortex in reading. Neuron. 2006;50:191-204 pubmed
    ..Altogether, these results provide direct evidence for the causal role of the left occipitotemporal cortex in the recognition of visual words...
  2. Cohen L, Martinaud O, Lemer C, Lehericy S, Samson Y, Obadia M, et al. Visual word recognition in the left and right hemispheres: anatomical and functional correlates of peripheral alexias. Cereb Cortex. 2003;13:1313-33 pubmed
    ..These data corroborate our initial model of normal word perception and underline that an alternative right-hemispheric pathway can underlie functional recovery from alexia...
  3. Rayner K, Johnson R. Letter-by-letter acquired dyslexia is due to the serial encoding of letters. Psychol Sci. 2005;16:530-4 pubmed
    Letter-by-letter acquired dyslexia (pure alexia) is assumed to be related to the serial encoding of letters, but the evidence for this assumption is somewhat indirect...
  4. Buxbaum L, Coslett H. Deep dyslexic phenomena in a letter-by-letter reader. Brain Lang. 1996;54:136-67 pubmed
  5. Schulte Körne G. Annotation: Genetics of reading and spelling disorder. J Child Psychol Psychiatry. 2001;42:985-97 pubmed
    ..However, the role of environmental factors should also be considered as the clinical implications of the genetic findings in terms of aetiology and intervention still require far more exploration...
  6. Lang C. [Agraphia of Gerstmann syndrome--attempt at characterization]. Fortschr Neurol Psychiatr. 1994;62:155-63 pubmed
    ..Lesions of these non-dominant areas may lead to spatial agraphia...
  7. Moss H, Tyler L. Investigating semantic memory impairments: the contribution of semantic priming. Memory. 1995;3:359-95 pubmed
    ..We then describe two recent studies in which we have employed semantic priming tasks, along with other more traditional methods, to investigate specific questions about the semantic memory deficits of three patients...
  8. Chanoine V, Ferreira C, Demonet J, Nespoulous J, Poncet M. Optic aphasia with pure alexia: a mild form of visual associative agnosia? A case study. Cortex. 1998;34:437-48 pubmed
    ..This symmetric performance between object and letter processing may also constitute a mild form of visual associative agnosia...
  9. Southwood M, Chatterjee A. The simultaneous activation hypothesis: explaining recovery from deep to phonological dyslexia. Brain Lang. 2001;76:18-34 pubmed
    ..The Simultaneous Activation Hypothesis readily accounts for the evolution from deep to phonological dyslexia...

More Information

Publications62

  1. Maher L, Clayton M, Barrett A, Schober Peterson D, Gonzalez Rothi L. Rehabilitation of a case of pure alexia: exploiting residual abilities. J Int Neuropsychol Soc. 1998;4:636-47 pubmed
    ..We propose that this patient's inability to benefit from the implicit semantic access treatment approach may be in part related to her inability to suppress the segmental letter identification process of word recognition...
  2. Colangelo A, Buchanan L, Westbury C. Deep dyslexia and semantic errors: a test of the failure of inhibition hypothesis using a semantic blocking paradigm. Brain Cogn. 2004;54:232-4 pubmed
    ..In addition, a semantic interference effect is expected. The results of semantic blocking were consistent with these predictions and lend support to the failure of inhibition hypothesis...
  3. Luo C, Anderson J, Caramazza A. Impaired stimulus-driven orienting of attention and preserved goal-directed orienting of attention in unilateral visual neglect. Am J Psychol. 1998;111:487-507 pubmed
    ..In contrast, the controlled goal-directed attentional search is largely preserved and can be used to alleviate neglect...
  4. Siakaluk P, Buchanan L. Stimulus-specific neglect in a deep dyslexic patient. Brain Cogn. 2001;46:268-71 pubmed
    ..Thus, it appears that B.V. also suffers from neglect dyslexia. We discuss how these two forms of dyslexia could be interacting to account for B.V.'s pattern of errors in reading aloud words and nonwords and in picture naming...
  5. Schuett S, Heywood C, Kentridge R, Zihl J. Rehabilitation of hemianopic dyslexia: are words necessary for re-learning oculomotor control?. Brain. 2008;131:3156-68 pubmed publisher
    ..Our results suggest that using words is not critical to the treatment effect of this training procedure. Thus, lexical-semantic processes seem not to be necessary for re-learning eye-movement control in hemianopic dyslexia...
  6. Laine M, Salmelin R, Helenius P, Marttila R. Brain activation during reading in deep dyslexia: an MEG study. J Cogn Neurosci. 2000;12:622-34 pubmed
    ..The observed variability emphasizes the importance of estimating consistency of brain activity both within and between measurements in brain-damaged individuals...
  7. Ortigue S, Mégevand P, Perren F, Landis T, Blanke O. Double dissociation between representational personal and extrapersonal neglect. Neurology. 2006;66:1414-7 pubmed
    ..In addition, perceptual neglect can be selectively observed within personal space or extrapersonal space. However, it is not known whether the latter dissociation also exists in representational neglect...
  8. Huntsman L. Testing the direct-access model: GOD does not prime DOG. Percept Psychophys. 1998;60:1128-40 pubmed
  9. Mimura M, Goodglass H, Milberg W. Preserved semantic priming effect in alexia. Brain Lang. 1996;54:434-46 pubmed
    ..The possibility of categorical gradient in implicit activation (living vs. nonliving) in BH was also discussed, which, however, needs to be clarified in the further investigation...
  10. Pyun S, Sohn H, Jung J, Nam K. Differential reorganization of fusiform gyrus in two types of alexia after stroke. Neurocase. 2007;13:417-25 pubmed publisher
    ..Also, the successful reorganization of the visual component of reading in the right FG is responsible for the recovery of LBL reading in pure alexia...
  11. Brousseau G, Buchanan L, Saunders C. An investigation into early acquired dyslexia. Neurocase. 2009;15:126-34 pubmed publisher
    ..To date however, there are few detailed investigations on cases of early acquired dyslexia. The purpose of this study was to examine such a case (participant referred to as SP)...
  12. Himeno E, Tanaka M, Araki T. [Kanji-predominant alexia with agraphia in opticospinal multiple sclerosis]. No To Shinkei. 2006;58:335-9 pubmed
  13. Kohnen S, Nickels L, Coltheart M, Brunsdon R. Predicting generalization in the training of irregular-word spelling: treating lexical spelling deficits in a child. Cogn Neuropsychol. 2008;25:343-75 pubmed publisher
    ..We suggest that the processes underlying treatment generalization are based on the interaction between the orthographic lexicon and the graphemic buffer. Clinical implications are discussed...
  14. Cohen L, Dehaene S, Chochon F, Lehericy S, Naccache L. Language and calculation within the parietal lobe: a combined cognitive, anatomical and fMRI study. Neuropsychologia. 2000;38:1426-40 pubmed
    ..Finally, the relative preservation of subtraction versus multiplication may be related to the fact that subtraction activated the intact right parietal lobe, while multiplication activated predominantly left-sided areas...
  15. Behrmann M, Nelson J, Sekuler E. Visual complexity in letter-by-letter reading: "pure" alexia is not pure. Neuropsychologia. 1998;36:1115-32 pubmed
    ..These findings suggest that the deficit giving rise to pure alexia is not restricted to orthographic symbols per se but, rather, is a consequence of damage to a more general-purpose visual processing mechanism...
  16. Barca L, Cappelli F, Amicuzi I, Apicella M, Castelli E, Stortini M. Modality-specific naming impairment after traumatic brain injury (TBI). Brain Inj. 2009;23:920-9 pubmed publisher
    ..To investigate neurocognitive and language functions in a single case presenting with modality-specific naming difficulties secondary to traumatic brain injury (TBI)...
  17. Shallice T, Rosazza C. Patterns of peripheral paralexia: pure alexia and the forgotten visual dyslexia?. Cortex. 2006;42:892-7 pubmed
    ..The lack of a serial letter processing strategy makes visual dyslexia a much more transparent functional syndrome...
  18. Warrington E, Langdon D. Does the spelling dyslexic read by recognizing orally spelled words? An investigation of a letter-by-letter reader. Neurocase. 2002;8:210-8 pubmed
    ..We conclude that in the reading-impaired patient there was a lexical deficit compensated for by the operation of a component of her intact spelling system...
  19. Henry M, BEESON P, Stark A, Rapcsak S. The role of left perisylvian cortical regions in spelling. Brain Lang. 2007;100:44-52 pubmed
    ..Further, degraded phonological input to orthographic selection typically results in additional deficits in real word spelling...
  20. Sato H, Patterson K, Fushimi T, Maxim J, Bryan K. Deep dyslexia for kanji and phonological dyslexia for kana: different manifestations from a common source. Neurocase. 2008;14:508-24 pubmed publisher
    ..The combination of deep dyslexia for kanji and phonological dyslexia for kana in a single patient suggests that these are not two distinct reading disorders...
  21. Ferreres A, López C, China N. Phonological alexia with vowel-consonant dissociation in non-word reading. Brain Lang. 2003;84:399-413 pubmed
    ..The case contributes to the discussion on the nature of representations and the processing of vowels and consonants...
  22. Paquier P, De Smet H, Mariën P, Poznanski N, Van Bogaert P. Acquired alexia with agraphia syndrome in childhood. J Child Neurol. 2006;21:324-30 pubmed
    ..This case is reminiscent of a historical childhood case reported in 1939 and is consonant with adult cases in terms of lesion location and semiologic picture...
  23. Hasumi T, Fukushima T, Haisa T, Yonemitsu T, Waragai M. Focal dural arteriovenous fistula (DAVF) presenting with progressive cognitive impairment including amnesia and alexia. Intern Med. 2007;46:1317-20 pubmed
    ..The case also shows that an intracranial DAVF may present as a variety of neurological symptoms, depending on its localization, size and clinical stage...
  24. Marangolo P, Nasti M, Zorzi M. Selective impairment for reading numbers and number words: a single case study. Neuropsychologia. 2004;42:997-1006 pubmed
  25. Pitchford N. Spoken language correlates of reading impairments acquired in childhood. Brain Lang. 2000;72:129-49 pubmed
  26. Law S, Wong W, Chiu K. Whole-word phonological representations of disyllabic words in the Chinese lexicon: data from acquired dyslexia. Behav Neurol. 2005;16:169-77 pubmed
    ..Theoretical arguments for whole-word form representations for all multisyllabic Chinese words are also discussed...
  27. Grigsby J, Kemper M, Hagerman R, Myers C. Neuropsychological dysfunction among affected heterozygous fragile X females. Am J Med Genet. 1990;35:28-35 pubmed
    ..Differences among heterozygous individuals in number of focal symptoms may reflect some variability in the penetrance of the fra(x) gene, as well as in the functional organization of the brain...
  28. Ciuffreda K, Han Y, Kapoor N, Ficarra A. Oculomotor rehabilitation for reading in acquired brain injury. NeuroRehabilitation. 2006;21:9-21 pubmed
  29. Fiset D, Gosselin F, Blais C, Arguin M. Inducing letter-by-letter dyslexia in normal readers. J Cogn Neurosci. 2006;18:1466-76 pubmed
    ..Experiment 3, conducted in LBL dyslexic L.H., shows that, indeed, the letter confusability effect is based on low spatial frequencies, whereas this effect was not supported by high spatial frequencies...
  30. Colangelo A, Buchanan L. Implicit and explicit processing in deep dyslexia: Semantic blocking as a test for failure of inhibition in the phonological output lexicon. Brain Lang. 2006;99:258-71 pubmed
    ..The results of the semantic blocking paradigm support the distinction between implicit and explicit processing and provide evidence for failure of inhibition as an explanation for semantic errors in deep dyslexia...
  31. Sakurai Y. Varieties of alexia from fusiform, posterior inferior temporal and posterior occipital gyrus lesions. Behav Neurol. 2004;15:35-50 pubmed
    ..To account for these impairments, a weighted dual-route hypothesis for reading is suggested...
  32. Cherney L. Aphasia, alexia, and oral reading. Top Stroke Rehabil. 2004;11:22-36 pubmed
    ..Finally, two case studies illustrate how oral reading of connected language (sentences and paragraphs rather than single words) has been used as a technique for treating alexia in patients with aphasia...
  33. Hall D, Humphreys G, Cooper A. Neuropsychological evidence for case-specific reading: multi-letter units in visual word recognition. Q J Exp Psychol A. 2001;54:439-67 pubmed
    ..These data cannot be explained in terms of letter-based reading or preserved holistic word recognition. We propose that GK was sensitive to the visual familiarity of adjacent letter forms...
  34. Márkus A. [Numbers, counting and calculating problems in view of cognitive neurology]. Ideggyogy Sz. 2010;63:95-112 pubmed
  35. Arduino L, Daini R, Caterina Silveri M. A stimulus-centered reading disorder for words and numbers: Is it neglect dyslexia?. Neurocase. 2005;11:405-15 pubmed
  36. Raman I, Weekes B. Acquired dyslexia in a Turkish-English speaker. Ann Dyslexia. 2005;55:79-104 pubmed
    ..To date, there has been no reported evidence of acquired dyslexia in Turkish speakers leading to the naïve view that reading and writing problems in Turkish are probably ..
  37. Glasspool D, Houghton G. Serial order and consonant-vowel structure in a graphemic output buffer model. Brain Lang. 2005;94:304-30 pubmed
    ..When the sequence generation process is disrupted by the addition of random noise the model shows the major features of GBD. The results are compared in detail against data from a number of patients...
  38. Behrmann M, Black S, McKeeff T, Barton J. Oculographic analysis of word reading in hemispatial neglect. Physiol Behav. 2002;77:613-9 pubmed
    ..This latter result suggests that the reading deficit may well arise from the failure to register and perceive the contralesional information...
  39. Kim H, Na D, Park E. Intransigent vowel-consonant position in Korean dysgraphia: evidence of spatial-constructive representation. Behav Neurol. 2007;18:91-7 pubmed
    ..This Korean graphemic configuration feature may be resistant to a focal, left cerebral damage, and thus, we also discuss our results in terms of cerebral lateralization of the writing processes...
  40. Park K, Yoon S. Dissociative disturbance in Hangul-Hanja reading after a left posterior occipital lesion. Behav Neurol. 2008;20:11-5 pubmed publisher
    ..This case demonstrates that Hangul-Hanja reading dissociation impairment can occur after occipital-parietal lesions...
  41. Käsmann B, Ruprecht K. Eclamptogenic Gerstmann's syndrome in combination with cortical agnosia and cortical diplopia. Ger J Ophthalmol. 1995;4:234-8 pubmed
    ..In our case the reason for such a dramatic clinical picture was eclampsia, whose prodomes had not been diagnosed in time...
  42. McDonald I. Musical alexia with recovery: a personal account. Brain. 2006;129:2554-61 pubmed
    ..Failure to maintain regular practice led to marked though recoverable deterioration. An increased frequency of migraine persisted for some 18 months...
  43. Friedmann N, Gvion A. Letter form as a constraint for errors in neglect dyslexia and letter position dyslexia. Behav Neurol. 2005;16:145-58 pubmed
    ..These data show that early visuo-orthographic analysis is sensitive to final letter form and that final letter form constrains errors in peripheral dyslexia...
  44. Rapcsak S, BEESON P. The role of left posterior inferior temporal cortex in spelling. Neurology. 2004;62:2221-9 pubmed
    ..To determine whether damage to left posterior inferior temporal cortex (PITC) is associated with agraphia and to characterize the nature of the spelling impairment...
  45. Luzzatti C, Laiacona M, Agazzi D. Multiple patterns of writing disorders in dementia of the Alzheimer type and their evolution. Neuropsychologia. 2003;41:759-72 pubmed
    ..Once again, the data showed high variability across subjects, and do not seem to support involvement of the sub-word-level spelling routine only at a late stage in the development of the disease...
  46. Butterworth B, Cappelletti M, Kopelman M. Category specificity in reading and writing: the case of number words. Nat Neurosci. 2001;4:784-6 pubmed
    ..Here we report the case of a neurodegenerative patient with selectively spared numerical abilities whose brain damage left him able to read and write only number words...
  47. Weekes B. Oral reading in Chinese: evidence from dementia of the Alzheimer's type. Int J Lang Commun Disord. 2000;35:543-59 pubmed
  48. Plaut D. Relearning after damage in connectionist networks: toward a theory of rehabilitation. Brain Lang. 1996;52:25-82 pubmed
    ..Taken together, the findings demonstrate that the nature of relearning in damaged connectionist networks can make important contributions to a theory of rehabilitation in patients...
  49. Ska B, Garneau Beaumont D, Chesneau S, Damien B. Diagnosis and rehabilitation attempt of a patient with acquired deep dyslexia. Brain Cogn. 2003;53:359-63 pubmed
    ..At the follow-up session, JH's reading performance for the trained words was still highly accurate at 84%. This strong effect is discussed and ways of increasing the patient's abilities to read are proposed...
  50. Leff A, Behrmann M. Treatment of reading impairment after stroke. Curr Opin Neurol. 2008;21:644-8 pubmed publisher
    ..In this review, we focus on the classification of acquired alexia and the current theory and practice underlying the rehabilitation of this diverse set of disorders...
  51. Schuett S. The rehabilitation of hemianopic dyslexia. Nat Rev Neurol. 2009;5:427-37 pubmed publisher
    ..Indeed, more research is required to further improve the efficiency of rehabilitation in patients with hemianopic dyslexia...
  52. Funnell E. Objects and properties: a study of the breakdown of semantic memory. Memory. 1995;3:497-518 pubmed
    ..The selective failure to recall specific information for some word meanings is discussed with reference to two theoretical accounts...
  53. Pierpont E, Ellis Weismer S, Roberts A, Tworog Dube E, Pierpont M, Mendelsohn N, et al. The language phenotype of children and adolescents with Noonan syndrome. J Speech Lang Hear Res. 2010;53:917-32 pubmed publisher
    ..Comparisons of language abilities among the different NS genotypes were also conducted...