infertility

Summary

Summary: A reduced or absent capacity to reproduce.

Top Publications

  1. Twig G, Shina A, Amital H, Shoenfeld Y. Pathogenesis of infertility and recurrent pregnancy loss in thyroid autoimmunity. J Autoimmun. 2012;38:J275-81 pubmed publisher
    ..A growing body of clinical studies links thyroid autoimmunity as a cause of infertility and adverse pregnancy outcomes that includes miscarriage or preterm deliveries...
  2. Sleha R, Bostikova V, Salavec M, Mosio P, Kusáková E, Kukla R, et al. [Bacterial infection as a cause of infertility in humans]. Epidemiol Mikrobiol Imunol. 2013;62:26-32 pubmed
    ..Infections of the urogenital tract are responsible for 15% of all cases of infertility in couples...
  3. Tabong P, Adongo P. Understanding the social meaning of infertility and childbearing: a qualitative study of the perception of childbearing and childlessness in Northern Ghana. PLoS ONE. 2013;8:e54429 pubmed publisher
    b>Infertility is a major medical condition that affects many married couples in sub-Saharan African and as such associated with several social meanings...
  4. Rouchou B. Consequences of infertility in developing countries. Perspect Public Health. 2013;133:174-9 pubmed publisher
    b>Infertility affects more than 10% of the world's population. In developing countries, there are severe social, psychological and economic consequences for infertile men and women...
  5. Dhawan B, Malhotra N, Sreenivas V, Rawre J, Khanna N, Chaudhry R, et al. Ureaplasma serovars & their antimicrobial susceptibility in patients of infertility & genital tract infections. Indian J Med Res. 2012;136:991-6 pubmed
    ..The aim of the present study was to determine the occurrence of Ureaplasma serovars in patients with infertility and genital tract infections with polymerase chain reaction (PCR)-based serotyping...
  6. Mascarenhas M, Flaxman S, Boerma T, Vanderpoel S, Stevens G. National, regional, and global trends in infertility prevalence since 1990: a systematic analysis of 277 health surveys. PLoS Med. 2012;9:e1001356 pubmed publisher
    Global, regional, and national estimates of prevalence of and tends in infertility are needed to target prevention and treatment efforts...
  7. Hammarberg K, Kirkman M. Infertility in resource-constrained settings: moving towards amelioration. Reprod Biomed Online. 2013;26:189-95 pubmed publisher
    It is often presumed that infertility is not a problem in resource-poor areas where fertility rates are high...
  8. Daniluk J, Koert E. The other side of the fertility coin: a comparison of childless men's and women's knowledge of fertility and assisted reproductive technology. Fertil Steril. 2013;99:839-46 pubmed publisher
    ..To determine childless men's knowledge about fertility and assisted reproductive technology (ART) treatments and family building options, compared to knowledge of a sample of childless women...
  9. Gradvohl S, Osis M, Makuch M. [Stress of men and women seeking treatment for infertility]. Rev Bras Ginecol Obstet. 2013;35:255-61 pubmed
    To evaluate the level of stress in men and women seeking treatment for infertility and to identify the associated variables.

More Information

Publications62

  1. Johnson L, Sasson I, Sammel M, Dokras A. Does intracytoplasmic sperm injection improve the fertilization rate and decrease the total fertilization failure rate in couples with well-defined unexplained infertility? A systematic review and meta-analysis. Fertil Steril. 2013;100:704-11 pubmed publisher
    To determine if intracytoplasmic sperm injection (ICSI), compared with conventional insemination, improves fertilization rates and prevents total failed fertilization (TFF) in couples with unexplained infertility.
  2. Clark N, Will M, Moravek M, Xu X, Fisseha S. Physician and patient use of and attitudes toward complementary and alternative medicine in the treatment of infertility. Int J Gynaecol Obstet. 2013;122:253-7 pubmed publisher
    To determine use of and attitudes toward complementary and alternative medicine (CAM) among infertility patients and subspecialty physicians.
  3. Tabong P, Adongo P. Infertility and childlessness: a qualitative study of the experiences of infertile couples in Northern Ghana. BMC Pregnancy Childbirth. 2013;13:72 pubmed publisher
    b>Infertility is a global reproductive health issue that affects many individuals and couples. Despite the high prevalence of infertility in Ghana, no study has been done on the experiences of infertile couples in Northern Ghana...
  4. Barton S, Najita J, Ginsburg E, Leisenring W, Stovall M, Weathers R, et al. Infertility, infertility treatment, and achievement of pregnancy in female survivors of childhood cancer: a report from the Childhood Cancer Survivor Study cohort. Lancet Oncol. 2013;14:873-81 pubmed publisher
    Previous studies have shown decreased pregnancy rates and early menopause in female cancer survivors; however, infertility rates and reproductive interventions have not been studied...
  5. Mumtaz Z, Shahid U, Levay A. Understanding the impact of gendered roles on the experiences of infertility amongst men and women in Punjab. Reprod Health. 2013;10:3 pubmed publisher
    While infertility is a global challenge for millions of couples, low income countries have particularly high rates, of up to 30%...
  6. Bardaweel S, Shehadeh M, Suaifan G, Kilani M. Complementary and alternative medicine utilization by a sample of infertile couples in Jordan for infertility treatment: clinics-based survey. BMC Complement Altern Med. 2013;13:35 pubmed publisher
    ..and alternative medicine (CAM), growing evidence suggests that CAM prevalence among patients seeking infertility treatment is increasing worldwide...
  7. Culley L, Hudson N, Lohan M. Where are all the men? The marginalization of men in social scientific research on infertility. Reprod Biomed Online. 2013;27:225-35 pubmed publisher
    There is a wealth of research exploring the psychological consequences of infertility and assisted reproduction technology, a substantial body of sociological and anthropological work on 'reproductive disruptions' of many kinds and a ..
  8. Bhattacharyya T, Gregorova S, Mihola O, Anger M, Sebestova J, Denny P, et al. Mechanistic basis of infertility of mouse intersubspecific hybrids. Proc Natl Acad Sci U S A. 2013;110:E468-77 pubmed publisher
    ..It is tempting to speculate that a fast-evolving subset of the noncoding genomic sequence important for chromosome pairing and synapsis may be the culprit...
  9. Gilleron J, Malassine A, Carette D, Segretain D, Pointis G. Chemical connexin impairment in the developing gonad associated with offspring infertility. Curr Med Chem. 2011;18:5145-58 pubmed
    ..Even if numerous studies argue for a relationship between male infertility and environmental and/or occupational exposure, the molecular mechanisms by which these anti-reproductive ..
  10. van Empel I, Dancet E, Koolman X, Nelen W, Stolk E, Sermeus W, et al. Physicians underestimate the importance of patient-centredness to patients: a discrete choice experiment in fertility care. Hum Reprod. 2011;26:584-93 pubmed publisher
    ..This study aimed to determine and compare the importance of patient-centredness, relative to pregnancy rates, to patients and physicians...
  11. Mourad S, Hermens R, Liefers J, Akkermans R, Zielhuis G, Adang E, et al. A multi-faceted strategy to improve the use of national fertility guidelines; a cluster-randomized controlled trial. Hum Reprod. 2011;26:817-26 pubmed publisher
    ..This study therefore contributes to an increased understanding of fertility guideline implementation in general, and the role of patients in particular...
  12. Nahar P. Health seeking behaviour of childless women in Bangladesh: an ethnographic exploration for the special issue on: loss in child bearing. Soc Sci Med. 2010;71:1780-7 pubmed publisher
    ..Consequently the childless women have to suffer in various ways as a result of their health seeking behaviour...
  13. van Empel I, Aarts J, Cohlen B, Huppelschoten D, Laven J, Nelen W, et al. Measuring patient-centredness, the neglected outcome in fertility care: a random multicentre validation study. Hum Reprod. 2010;25:2516-26 pubmed publisher
    ..This study aims to develop and validate an instrument that can reliably measure patient-centredness in fertility care: patient-centredness questionnaire-infertility (PCQ-infertility).
  14. van Loendersloot L, van Wely M, Limpens J, Bossuyt P, Repping S, van der Veen F. Predictive factors in in vitro fertilization (IVF): a systematic review and meta-analysis. Hum Reprod Update. 2010;16:577-89 pubmed publisher
    ..These models differ from one another in the predictors they include. We performed a systematic review and meta-analysis to identify the most relevant predictors for success in IVF...
  15. Puumala S, Spector L, Wall M, Robison L, Heerema N, Roesler M, et al. Infant leukemia and parental infertility or its treatment: a Children's Oncology Group report. Hum Reprod. 2010;25:1561-8 pubmed publisher
    ..With its very young age at diagnosis, exposures occurring in the perinatal period are suspected. Parental infertility and infertility treatment have been studied with regard to childhood cancer in general, but rarely in ..
  16. Galhardo A, Cunha M, Pinto Gouveia J. Measuring self-efficacy to deal with infertility: Psychometric properties and confirmatory factor analysis of the Portuguese version of the infertility self-efficacy scale. Res Nurs Health. 2013;36:65-74 pubmed publisher
    This study explores the psychometric properties and factor structure of the Portuguese version of the Infertility Self-Efficacy Scale (ISE-P), using translation and back-translation of the original version; principal component analysis; ..
  17. Nelson S, Messow M, McConnachie A, Wallace H, Kelsey T, Fleming R, et al. External validation of nomogram for the decline in serum anti-Müllerian hormone in women: a population study of 15,834 infertility patients. Reprod Biomed Online. 2011;23:204-6 pubmed publisher
    ..This nomogram can therefore be used with confidence for the interpretation of AMH in clinical populations...
  18. Tranfo G, Caporossi L, Paci E, Aragona C, Romanzi D, De Carolis C, et al. Urinary phthalate monoesters concentration in couples with infertility problems. Toxicol Lett. 2012;213:15-20 pubmed publisher
    ..A further step will be the correlation of these results with information on the life styles and working conditions collected through a specifically designed questionnaire...
  19. De Sutter P. Considerations for clinics and practitioners treating foreign patients with assisted reproductive technology: lessons from experiences at Ghent University Hospital, Belgium. Reprod Biomed Online. 2011;23:652-6 pubmed publisher
    ..All should be done to avoid that cross-border patients compromise the local care system. Special arrangements should be taken to manage possible complications following treatment...
  20. Grether J, Qian Y, Croughan M, Wu Y, Schembri M, Camarano L, et al. Is infertility associated with childhood autism?. J Autism Dev Disord. 2013;43:663-72 pubmed publisher
    Concerns persist about a possible link between infertility and risk of autism spectrum disorders (ASD). Interpretation of existing studies is limited by racial/ethnic homogeneity of study populations and other factors...
  21. Northrup E, Zschemisch N, Eisenblätter R, Glage S, Wedekind D, Cuppen E, et al. The ter mutation in the rat Dnd1 gene initiates gonadal teratomas and infertility in both genders. PLoS ONE. 2012;7:e38001 pubmed publisher
    ..Teratocarcinogenesis was accompanied by infertility and the underlying mutation was termed ter...
  22. van Montfoort A, Hanssen L, De Sutter P, Viville S, Geraedts J, de Boer P. Assisted reproduction treatment and epigenetic inheritance. Hum Reprod Update. 2012;18:171-97 pubmed publisher
    ..Hence, there is a growing literature, including mouse studies...
  23. Blyth E, Thorn P, Wischmann T. CBRC and psychosocial counselling: assessing needs and developing an ethical framework for practice. Reprod Biomed Online. 2011;23:642-51 pubmed publisher
    Encountering infertility and involuntary childlessness and undergoing infertility treatment are acknowledged as stressful experiences that impact on individuals' psychological and emotional health – and for which access to psychosocial ..
  24. Bovey M, Lorenc A, Robinson N. Extent of acupuncture practice for infertility in the United Kingdom: experiences and perceptions of the practitioners. Fertil Steril. 2010;94:2569-73 pubmed publisher
    ..To investigate acupuncture practitioners' experience and perceptions of supporting patients presenting with fertility issues...
  25. Caleshu C, Shiloh S, Price C, Sapp J, Biesecker B. Invasive prenatal testing decisions in pregnancy after infertility. Prenat Diagn. 2010;30:575-81 pubmed publisher
    This study assessed decisional conflict about invasive prenatal testing among women pregnant after infertility. We surveyed 180 pregnant women with a history of infertility using a mixed methods cross-sectional design...
  26. Andersen D, Løssl K, Nyboe Andersen A, Fürbringer J, Bach H, Simonsen J, et al. Acupuncture on the day of embryo transfer: a randomized controlled trial of 635 patients. Reprod Biomed Online. 2010;21:366-72 pubmed publisher
    ..The differences were not statistically significant. These results suggest that acupuncture administered in relation to embryo transfer has no effect on the outcome of IVF and ICSI...
  27. Sagnella F, Moro F, Lanzone A, Tropea A, Martinez D, Capalbo A, et al. A prospective randomized noninferiority study comparing recombinant FSH and highly purified menotropin in intrauterine insemination cycles in couples with unexplained infertility and/or mild-moderate male factor. Fertil Steril. 2011;95:689-94 pubmed publisher
    ..To demonstrate the noninferiority of highly purified menotropin (HP-hMG) compared with recombinant FSH (rFSH) regarding clinical pregnancy rate (PR) in intrauterine insemination (IUI) cycles...
  28. Schendelaar P, Middelburg K, Bos A, Heineman M, Jongbloed Pereboom M, Hadders Algra M. The Groningen ART cohort study: the effects of ovarian hyperstimulation and the IVF laboratory procedures on neurological condition at 2 years. Hum Reprod. 2011;26:703-12 pubmed publisher
    ..Our aim was to evaluate the effects of ovarian hyperstimulation, IVF laboratory procedures and a history of subfertility on neurological condition at 2 years...
  29. Olsen J, Zhu J, Ramlau Hansen C. Has fertility declined in recent decades?. Acta Obstet Gynecol Scand. 2011;90:129-35 pubmed publisher
    Increasing use of infertility treatment and a decline in demographic fertility in some countries have raised concern whether human fecundity is declining or has declined over time...
  30. Aarts J, Faber M, Van Empel I, Scheenjes E, Nelen W, Kremer J. Professionals' perceptions of their patients' experiences with fertility care. Hum Reprod. 2011;26:1119-27 pubmed publisher
    ..The objective of the present study was to determine to what extent gynaecologists, physicians specializing in infertility and nurses can estimate the level of patient-centredness of their clinic.
  31. Gurunath S, Pandian Z, Anderson R, Bhattacharya S. Defining infertility--a systematic review of prevalence studies. Hum Reprod Update. 2011;17:575-88 pubmed publisher
    Existing definitions of infertility lack uniformity, rendering comparisons in prevalence between countries or over time problematic...
  32. Verhaak C, Lintsen A, Evers A, Braat D. Who is at risk of emotional problems and how do you know? Screening of women going for IVF treatment. Hum Reprod. 2010;25:1234-40 pubmed publisher
    ..This study investigated the psychometric characteristics of a screening tool SCREENIVF to identify women at risk of emotional problems at an early stage of treatment...
  33. Blyth E. Fertility patients' experiences of cross-border reproductive care. Fertil Steril. 2010;94:e11-5 pubmed publisher
    ..To obtain pertinent information from individuals who have either experienced cross-border reproductive care, or have considered doing so...
  34. te Velde E, Burdorf A, Nieschlag E, Eijkemans R, Kremer J, Roeleveld N, et al. Is human fecundity declining in Western countries?. Hum Reprod. 2010;25:1348-53 pubmed publisher
    ..If we want to find out whether or not population fecundity will be declining within the following 20-30 years, we must start monitoring now...
  35. Balasch J. Ageing and infertility: an overview. Gynecol Endocrinol. 2010;26:855-60 pubmed publisher
    ..Female fertility has a 'best-before date' of 35, and for men, it is probably before age 45-50...
  36. McDowell S, Murray A. Barriers to continuing in vitro fertilisation--why do patients exit fertility treatment?. Aust N Z J Obstet Gynaecol. 2011;51:84-90 pubmed publisher
    ..Many couples do not complete IVF treatment. There is little published data regarding this issue and also what changes might lead to better compliance rates...
  37. Gameiro S, Boivin J, Peronace L, Verhaak C. Why do patients discontinue fertility treatment? A systematic review of reasons and predictors of discontinuation in fertility treatment. Hum Reprod Update. 2012;18:652-69 pubmed publisher
    ..Patients should be well informed, have the opportunity to discuss values and worries about treatment and receive advice to decide about continuing treatment...
  38. Culley L, Hudson N, Rapport F, Blyth E, Norton W, Pacey A. Crossing borders for fertility treatment: motivations, destinations and outcomes of UK fertility travellers. Hum Reprod. 2011;26:2373-81 pubmed publisher
  39. Beall S, DeCherney A. History and challenges surrounding ovarian stimulation in the treatment of infertility. Fertil Steril. 2012;97:795-801 pubmed publisher
    ..To examine the history of superovulation for ovulation induction, its contributions to reproductive medicine, and its impact on multiple births...
  40. Zhu J, Obel C, Basso O, Henriksen T, Bech B, Hvidtjørn D, et al. Infertility, infertility treatment and behavioural problems in the offspring. Paediatr Perinat Epidemiol. 2011;25:466-77 pubmed publisher
    Behavioural patterns in children of infertile couples may be influenced by both the underlying causes of infertility and stress in the couples...
  41. Nomikos M, Swann K, Lai F. Starting a new life: sperm PLC-zeta mobilizes the Ca2+ signal that induces egg activation and embryo development: an essential phospholipase C with implications for male infertility. Bioessays. 2012;34:126-34 pubmed publisher
    ..Recent advances have refined our understanding of how PLC? induces Ca(2+) oscillations in the egg and also suggest its potential dysfunction as a cause of male infertility.
  42. Johnson M. Robert Edwards: the path to IVF. Reprod Biomed Online. 2011;23:245-62 pubmed publisher
    ..Steptoe’simpact on Edwards was twofold. First, Steptoe’s long-held interest in infertility raised this application of IVF higher in Edwards’priorities...
  43. Etuk S. Reproductive health: global infertility trend. Niger J Physiol Sci. 2009;24:85-90 pubmed
  44. Bajoria R, Chatterjee R. Hypogonadotrophic hypogonadism and diminished gonadal reserve accounts for dysfunctional gametogenesis in thalassaemia patients with iron overload presenting with infertility. Hemoglobin. 2011;35:636-42 pubmed publisher
    ..Better outcome is expected in females than males. We report the first two cases of paternity following IVF and ICSI in ?-TM patients with HH...
  45. Speier A. Brokers, consumers and the internet: how North American consumers navigate their infertility journeys. Reprod Biomed Online. 2011;23:592-9 pubmed publisher
    North Americans who suffer infertility often reach an end to treatment options at home, whether it is due to a lack of egg donors in Canada or the high cost of treatment in the USA...
  46. Fuchs B, Muller K, Paasch U, Schiller J. Lysophospholipids: potential markers of diseases and infertility?. Mini Rev Med Chem. 2012;12:74-86 pubmed
    ..Finally, the effects of LPL as signaling molecules and their roles in different pathologies such as infertility, cancer, atherosclerosis or inflammatory diseases are discussed...
  47. Wang C, Yang C, Chen X, Yao B, Yang C, Zhu C, et al. Altered profile of seminal plasma microRNAs in the molecular diagnosis of male infertility. Clin Chem. 2011;57:1722-31 pubmed publisher
    ..We investigated the profile of seminal plasma miRNAs in infertile men to identify miRNAs that are altered in infertility; we then evaluated their diagnostic value.
  48. Goedeke S, Payne D. A qualitative study of New Zealand fertility counsellors' roles and practices regarding embryo donation. Hum Reprod. 2010;25:2821-8 pubmed publisher
    ..This study explores the roles and practices of fertility counsellors in the context of New Zealand's policies...
  49. Scott R, Ferry K, Su J, Tao X, Scott K, Treff N. Comprehensive chromosome screening is highly predictive of the reproductive potential of human embryos: a prospective, blinded, nonselection study. Fertil Steril. 2012;97:870-5 pubmed publisher
    ..To determine both the negative and positive predictive values of comprehensive chromosome screening (CCS) results for clinical outcome...
  50. Chang C, Chang H, Chen C, Lin C, Chen C, Lai C, et al. MUC4 gene polymorphisms associate with endometriosis development and endometriosis-related infertility. BMC Med. 2011;9:19 pubmed publisher
    ..Mucin 4 (MUC4) plays an important role in protecting and lubricating the epithelial surface of reproductive tracts, but its role in the pathogenesis of endometriosis is largely unknown...
  51. Poulakou Rebelakou E, Tsiamis C, Tompros N, Creatsas G. The lack of a child, the loss of a throne: the infertility of the first royal couple of Greece (1833-62). J R Coll Physicians Edinb. 2011;41:73-7 pubmed publisher
    ..by Greek and German physicians, especially Amalia, who was considered to be largely responsible for the infertility. In this paper we discuss possible diagnoses and describe the various treatments suggested for, and applied to, ..
  52. Rauprich O, Berns E, Vollmann J. Information provision and decision-making in assisted reproduction treatment: results from a survey in Germany. Hum Reprod. 2011;26:2382-91 pubmed publisher
    ..The objective of this study was to investigate the views of patients and experts in Germany on information provision and decision-making in assisted reproduction treatment (ART)...
  53. Schmidt L, Sobotka T, Bentzen J, Nyboe Andersen A. Demographic and medical consequences of the postponement of parenthood. Hum Reprod Update. 2012;18:29-43 pubmed publisher
    ..were searched for publications on relevant subjects such as delayed parenthood, female and male age, fertility, infertility, time to pregnancy (TTP), fetal death, outcome of medically assisted reproduction (MAR) and mental well-being...