1 butanol

Summary

Summary: A four carbon linear hydrocarbon that has a hydroxy group at position 1.

Top Publications

  1. Tomas C, Welker N, Papoutsakis E. Overexpression of groESL in Clostridium acetobutylicum results in increased solvent production and tolerance, prolonged metabolism, and changes in the cell's transcriptional program. Appl Environ Microbiol. 2003;69:4951-65 pubmed
    ..Both transcriptional and Western analyses revealed elevated stress protein expression in the plasmid-carrying strain...
  2. Krinke O, Flemr M, Vergnolle C, Collin S, Renou J, Taconnat L, et al. Phospholipase D activation is an early component of the salicylic acid signaling pathway in Arabidopsis cell suspensions. Plant Physiol. 2009;150:424-36 pubmed publisher
    ..The overlap with the previously described phosphatidylinositol-4-kinase pathway is discussed...
  3. Borden J, Papoutsakis E. Dynamics of genomic-library enrichment and identification of solvent tolerance genes for Clostridium acetobutylicum. Appl Environ Microbiol. 2007;73:3061-8 pubmed
    ..Further characterization of the genes identified in this study will likely enhance our understanding of the complex phenotype of solvent tolerance...
  4. Wilk A, Grajkowski A, Chmielewski M, Beaucage S, Phillips L. Deoxyribonucleoside phosphoramidites. Curr Protoc Nucleic Acid Chem. 2001;Chapter 2:Unit 2.7 pubmed publisher
    ..Two syntheses of phosphoramidites starting from either a phosphordichloridite precursor or a bis-(N,N-diisopropylamino)chlorophosphine intermediate are described for the phosphinylation of suitably protected deoxyribonucleosides...
  5. Teeguarden J, Deisinger P, Poet T, English J, Faber W, Barton H, et al. Derivation of a human equivalent concentration for n-butanol using a physiologically based pharmacokinetic model for n-butyl acetate and metabolites n-butanol and n-butyric acid. Toxicol Sci. 2005;85:429-46 pubmed
    ..Human equivalent concentrations of 169 ppm and 1066 ppm n-butanol corresponding to the rat n-butyl acetate NOAELs of 500 and 3000 ppm were derived using the models...
  6. Wang Y, Oram J. Unsaturated fatty acids phosphorylate and destabilize ABCA1 through a phospholipase D2 pathway. J Biol Chem. 2005;280:35896-903 pubmed
    ..These data provide evidence that intracellular unsaturated acyl-CoA derivatives destabilize ABCA1 by activating a PLD2 signaling pathway...
  7. Ahn B, Min G, Bae Y, Bae Y, Min D. Phospholipase D is activated and phosphorylated by casein kinase-II in human U87 astroglioma cells. Exp Mol Med. 2006;38:55-62 pubmed
    ..These results suggest that CKII is involved in proliferation of U87 cells at least in part, through stimulation of PLD activity...
  8. Nielsen D, Prather K. In situ product recovery of n-butanol using polymeric resins. Biotechnol Bioeng. 2009;102:811-21 pubmed publisher
    ..Due to its modular nature, the proposed ISPR design exhibits strong potential for compatibility with future n-butanol fermentation efforts...
  9. Qureshi N, Saha B, Cotta M. Butanol production from wheat straw hydrolysate using Clostridium beijerinckii. Bioprocess Biosyst Eng. 2007;30:419-27 pubmed
    ..Medium containing 250 g L(-1) glucose resulted in no growth and no ABE production. Mixtures containing WSH + 140 g L(-1) glucose (total sugar approximately 200 g L(-1)) showed poor growth and poor ABE production...

More Information

Publications62

  1. Zareena A, Variyar P, Gholap A, Bongirwar D. Chemical investigation of gamma-irradiated saffron (Crocus sativus L.). J Agric Food Chem. 2001;49:687-91 pubmed
    ..Analysis of these fractions by HPLC revealed a decrease in glucosides and an increase in aglycon content in irradiated samples. The possibility of degradation of pigments during gamma irradiation is discussed...
  2. Bevilaqua T, da Silva D, Machado V. Preferential solvation of Brooker's merocyanine in binary solvent mixtures composed of formamides and hydroxylic solvents. Spectrochim Acta A Mol Biomol Spectrosc. 2004;60:951-8 pubmed
    ..The results suggest that both hydrogen bonding and solvophobic interactions contribute to the formation of the solvent complexes responsible for the observed synergistic effects in the PS of the dye...
  3. Shen Y, Xu L, Foster D. Role for phospholipase D in receptor-mediated endocytosis. Mol Cell Biol. 2001;21:595-602 pubmed
    ..EGF-induced activation of mitogen-activated protein kinase, which is dependent upon receptor endocytosis, is also dependent upon PLD. These data suggest a role for PLD in signaling that facilitates receptor endocytosis...
  4. Reinhard J, Sinclair M, Srinivasan M, Claudianos C. Honeybees learn odour mixtures via a selection of key odorants. PLoS ONE. 2010;5:e9110 pubmed publisher
    ..Most of these odours are floral scents, which are mixtures of dozens of different odorants. To date, it is still unclear how the bee brain unravels the complex information contained in scent mixtures...
  5. Monreal J, López Baena F, Vidal J, Echevarría C, García Mauriño S. Involvement of phospholipase D and phosphatidic acid in the light-dependent up-regulation of sorghum leaf phosphoenolpyruvate carboxylase-kinase. J Exp Bot. 2010;61:2819-27 pubmed publisher
  6. Ahmad B, Shah S, Bashir S, Shah J. Enzyme inhibition activities of Andrachne cardifolia Muell. J Enzyme Inhib Med Chem. 2007;22:235-8 pubmed
    ..The crude methanolic extract and its various fractions demonstrated poor to significant activity (25-73%) against acetylcholinesterase and no activity against urease...
  7. Han P, Yuan Y. Lipidomic analysis reveals activation of phospholipid signaling in mechanotransduction of Taxus cuspidata cells in response to shear stress. FASEB J. 2009;23:623-30 pubmed publisher
    ..cuspidata cells. These results demonstrate that phospholipids and related phospholipases play important roles in mechanotransduction of T. cuspidata cells in response to shear stress...
  8. Bhattacharji A, Kaplan B, Harris T, Qu X, Germann M, Covarrubias M. The concerted contribution of the S4-S5 linker and the S6 segment to the modulation of a Kv channel by 1-alkanols. Mol Pharmacol. 2006;70:1542-54 pubmed
    ..Therefore, we propose that amphiphilic general anesthetic agents such as 1-alkanols may modulate gating of the Shaw2 K(+) channel by an interaction with its activation gate...
  9. Piera Velazquez S, Marhuenda Egea F, Cadenas E. Increased stability of malate dehydrogenase from Halobacterium salinarum at low salt concentration in reverse micelles. Extremophiles. 2002;6:407-12 pubmed
    ..These observations indicate that reverse micelles provide a microenvironment that allows a much greater stability of this enzyme compared with an aqueous medium...
  10. Kabelitz N, Santos P, Heipieper H. Effect of aliphatic alcohols on growth and degree of saturation of membrane lipids in Acinetobacter calcoaceticus. FEMS Microbiol Lett. 2003;220:223-7 pubmed
  11. Kim H, Ha J, Park S, Yang K. Presence of hexobarbital in primary cultures of rat hepatocytes maintains cytochrome P-450 levels and drug metabolizing enzyme activities. Drug Chem Toxicol. 1988;11:29-41 pubmed
    ..Additions of other substrates of hepatic mixed function oxidase to the culture medium did not protect against the loss of cytochrome P-450 and enzyme activities...
  12. Albrecht J, Schreder T, Kleemann A, Schöpf V, Kopietz R, Anzinger A, et al. Olfactory detection thresholds and pleasantness of a food-related and a non-food odour in hunger and satiety. Rhinology. 2009;47:160-5 pubmed
    ..Instead our findings that satiety decreases the pleasantness of a food-related odour support the hypothesis that both odour threshold as well as pleasantness play an important role in the control of food intake...
  13. Hammady T, Nadeau V, Hildgen P. Microemulsion and diafiltration approaches: an attempt to maximize the global yield of DNA-loaded nanospheres. Eur J Pharm Biopharm. 2006;62:143-54 pubmed
    ..e. production yield, a modified diafiltration technique was adopted for the washing and recovery processes in comparison with the traditional and for the conservation of particle size characteristics of the recovered nanospheres...
  14. Krebs S, Fischaleck M, Blum H. A simple and loss-free method to remove TRIzol contaminations from minute RNA samples. Anal Biochem. 2009;387:136-8 pubmed publisher
    ..Application of the method is demonstrated for fluorescence-activated cell sorting (FACS)-sorted cells where the population of interest is often small...
  15. Quitschke W. Differential solubility of curcuminoids in serum and albumin solutions: implications for analytical and therapeutic applications. BMC Biotechnol. 2008;8:84 pubmed publisher
    ..Unfortunately, the solubility of curcuminoids in aqueous solutions is exceedingly low. This restricts their systemic availability in orally administered formulations and limits their therapeutic potential...
  16. Gugliuzza A, Fabiano R, Garavaglia M, Spisso A, Drioli E. Study of the surface character as responsible for controlling interfacial forces at membrane-feed interface. J Colloid Interface Sci. 2006;303:388-403 pubmed
    ..As a result, the quantification of the reactivity of a membrane surface for specific molecules may allow predictive models to be constructed and selective membranes to be designed...
  17. Sonoda H, Okada T, Jahangeer S, Nakamura S. Requirement of phospholipase D for ilimaquinone-induced Golgi membrane fragmentation. J Biol Chem. 2007;282:34085-92 pubmed
  18. Chen J, Chang Y, Wu S, Chao D, Chang C, Li C, et al. Inhibition of Escherichia coli heat-labile enterotoxin-induced diarrhea by Chaenomeles speciosa. J Ethnopharmacol. 2007;113:233-9 pubmed
    ..In conclusion, our findings suggested that oleanolic acid, ursolic acid, and betulinic acid were the active constituents from FC and might be considered as lead therapeutic agents in the treatment of LT-induced diarrhea...
  19. Ong A, Kamaruddin A, Bhatia S, Aboul Enein H. Enantioseparation of (R,S)-ketoprofen using Candida antarctica lipase B in an enzymatic membrane reactor. J Sep Sci. 2008;31:2476-85 pubmed publisher
    ..Immobilized CALB in the EMR assured higher reaction capacity, better thermal stability, and reusability. It was also found to be more cost effective and practical than free CALB in a batch reactor...
  20. Cann A, Liao J. Production of 2-methyl-1-butanol in engineered Escherichia coli. Appl Microbiol Biotechnol. 2008;81:89-98 pubmed publisher
    ..This work led to a strain of E. coli that produces 1.25 g/L 2MB in 24 h, a total alcohol content of 3 g/L, and with yields of up to 0.17 g 2MB/g glucose...
  21. Shiflett M, Yokozeki A. Vapor-liquid-liquid equilibria of pentafluoroethane and ionic liquid [bmim][PF6] mixtures studied with the volumetric method. J Phys Chem B. 2006;110:14436-43 pubmed
    ..In addition, we have found very large negative excess molar volumes in this system...
  22. Caboi F, Lazzari P, Pani L, Monduzzi M. Effect of 1-butanol on the microstructure of lecithin/water/tripalmitin system. Chem Phys Lipids. 2005;135:147-56 pubmed
    ..The self-diffusion coefficients of the different components along oil and water dilution lines indicate a microstructural organization characterized by a highly connected water in oil domains...
  23. Lu X, Vora H, Khosla C. Overproduction of free fatty acids in E. coli: implications for biodiesel production. Metab Eng. 2008;10:333-9 pubmed publisher
    ..coli strain, with a specific productivity of 0.024 g/h/g dry cell mass and a peak conversion efficiency of 4.8% of the carbon source into fatty acid products. At least 50% of the fatty acids produced were present in the free acid form...
  24. Valderrama P, Poppi R. Bilinear least squares (BLLS) and molecular fluorescence in the quantification of the propranolol enantiomers. Anal Chim Acta. 2008;623:38-45 pubmed publisher
    ..71% and 0.84% for the pure form and pharmaceutical preparations, respectively. These results indicate that the proposed methodology can be an alternative for the determination of propranolol enantiomeric composition...
  25. Lin Y, Chou H, Sarma L, Hwang B. Stacking structure of confined 1-butanol in SBA-15 investigated by solid-state NMR spectroscopy. Chemistry. 2009;15:10658-65 pubmed publisher
  26. Langhans M, Robinson D. 1-Butanol targets the Golgi apparatus in tobacco BY-2 cells, but in a different way to Brefeldin A. J Exp Bot. 2007;58:3439-47 pubmed
    ..Thus, although both inhibitors had the Golgi apparatus as their principle cytological target and both interfere with coatomer attachment, they differ in their ability to induce an interaction with the ER...
  27. Atsumi S, Cann A, Connor M, Shen C, Smith K, Brynildsen M, et al. Metabolic engineering of Escherichia coli for 1-butanol production. Metab Eng. 2008;10:305-11 pubmed
    ..Alternative genes and competing pathway deletions were evaluated for 1-butanol production. Results show promise for using E. coli for 1-butanol production...
  28. Deshpande A, Nimsadkar S, Mande S. Effect of alcohols on protein hydration: crystallographic analysis of hen egg-white lysozyme in the presence of alcohols. Acta Crystallogr D Biol Crystallogr. 2005;61:1005-8 pubmed
    ..It is believed that the disorder induced in the water molecules is a direct consequence of alcohol binding...
  29. Glitsch M. Activation of native TRPC3 cation channels by phospholipase D. FASEB J. 2010;24:318-25 pubmed publisher
    ..These results reveal a new mechanism for the gating of the ubiquitous TRPC3 channel and identify a key role for phospholipase D in the generation of the slow excitatory postsynaptic current in cerebellar Purkinje cells...
  30. Harris T, Shahidullah M, Ellingson J, Covarrubias M. General anesthetic action at an internal protein site involving the S4-S5 cytoplasmic loop of a neuronal K(+) channel. J Biol Chem. 2000;275:4928-36 pubmed
    ..A new working hypothesis proposes that 1-alkanols lock dShaw2 channels in their closed conformation by a direct interaction at a crevice formed by the S4-S5 loop...
  31. Li W, Ren B, Min Zhuo -, Hu Y, Lu C, Wu J, et al. The anti-hyperglycemic effect of plants in genus Gynura Cass. Am J Chin Med. 2009;37:961-6 pubmed
    ..bicolor showed very significant effect on lowering blood glucose level to normal and alloxan-diabetic mice, and the dose 4.0 g (crude drug)/kg had a more hypoglycemic effect than 50 mg/kg glyburide in normal mice...
  32. Palonen S, Jussila M, Porras S, Hyötyläinen T, Riekkola M. Nonaqueous capillary electrophoresis with alcoholic background electrolytes: separation efficiency under high electrical field strengths. Electrophoresis. 2002;23:393-9 pubmed
    ..Capillary preconditioning had a varied effect on the separations in the different BGEs as the BGE and the conditioning process affected the electroosmotic flow (EOF) velocity and direction...
  33. Milara J, Mata M, Mauricio M, Donet E, Morcillo E, Cortijo J. Sphingosine-1-phosphate increases human alveolar epithelial IL-8 secretion, proliferation and neutrophil chemotaxis. Eur J Pharmacol. 2009;609:132-9 pubmed publisher
    ..This study demonstrates for the first time that S1P participates in the alveolar epithelial interactions in vitro. ..
  34. Hu Q, Natarajan V, Ziegelstein R. Phospholipase D regulates calcium oscillation frequency and nuclear factor-kappaB activity in histamine- stimulated human endothelial cells. Biochem Biophys Res Commun. 2002;292:325-32 pubmed
    ..This study shows that activation of PLD by histamine regulates [Ca(2+)](i) oscillation frequency and NF-kappaB activity in HAEC...
  35. Lee S, Han J, Seo J, Cha Y. Modulation of cyclooxygenase-2 expression by phosphatidylcholine specific phospholipase C and D in macrophages stimulated with lipopolysaccharide. Mol Cells. 2003;15:320-6 pubmed
    ..These results suggest that inhibitors of PC-PLC, PKC and PC-PLD, or activators of PPH could be useful in the management of LPS-induced overproduction of prostaglandins and of vascular dysfunction in septic shock...
  36. Bollag W, Jung E, Calle R. Mechanism of angiotensin II-induced phospholipase D activation in bovine adrenal glomerulosa cells. Mol Cell Endocrinol. 2002;192:7-16 pubmed
    ..Thus, our results suggest a role for PKC, independent of calcium influx, in mediating AngII-induced PLD activation in glomerulosa cells...
  37. El Shiekh R, Zahran F, El Fetouh Gouda A. Spectrophotometric determination of some anti-tussive and anti-spasmodic drugs through ion-pair complex formation with thiocyanate and cobalt(II) or molybdenum(V). Spectrochim Acta A Mol Biomol Spectrosc. 2007;66:1279-87 pubmed
  38. Wang G, Lin J, Jiang X, Li Z. Cholesterol-appended aromatic imine organogelators: a case study of gelation-driven component selection. Langmuir. 2009;25:8414-8 pubmed publisher
  39. Okot Kotber M, Liavoga A, Yong K, Bagorogoza K. Activation of polyphenol oxidase in extracts of bran from several wheat (Triticum aestivum) cultivars using organic solvents, detergents, and chaotropes. J Agric Food Chem. 2002;50:2410-7 pubmed
    ..It is hypothesized that in wheat PPO exists in an inactive form which may be activated by the presence of activators, hitherto unknown, similar in effect to that elicited by the chemical denaturants in this study...
  40. Lee H, Kang H, Jo E, Kim J, Lee Y, Lee S, et al. Trp-Lys-Tyr-Met-Val-Met stimulates phagocytosis via phospho-lipase D-dependent signaling in mouse dendritic cells. Exp Mol Med. 2004;36:135-44 pubmed
    ..4 as well as in mouse bone marrow-derived dendritic cells, this study suggests that the activation of FPR family by WKYMVM stimulates the PLD activity resulting in phagocytic activity in DC2.4 cells...
  41. Bonnefoy C, Menudier A, Moesch C, Lachatre G, Mermet J. Determination of chromium in whole blood by DRC-ICP-MS: spectral and non-spectral interferences. Anal Bioanal Chem. 2005;383:167-73 pubmed
    ..By comparing the slopes and calculating residues, it was proved that the plot obtained with standard additions and the plot obtained from blood samples of different concentrations were aligned down to 0.05 microg L(-1) after dilution...
  42. Song G, Qin T, Liu H, Xu G, Pan Y, Xiong F, et al. Quantitative breath analysis of volatile organic compounds of lung cancer patients. Lung Cancer. 2010;67:227-31 pubmed publisher
  43. Grotto D, Santa Maria L, Boeira S, Valentini J, Charão M, Moro A, et al. Rapid quantification of malondialdehyde in plasma by high performance liquid chromatography-visible detection. J Pharm Biomed Anal. 2007;43:619-24 pubmed
    ..Thus, a specific and reliable method for MDA determination in plasma by high performance liquid chromatographic (HPLC)-VIS was validated; alkaline hydrolysis, n-butanol extraction steps and MDA stability were established...
  44. Junyaprasert V, Boonme P, Wurster D, Rades T. Aerosol OT microemulsions as carriers for transdermal delivery of hydrophobic and hydrophilic local anesthetics. Drug Deliv. 2008;15:323-30 pubmed
    ..Moreover, the skin permeation of drug from microemulsions depended on drug molecular structure and interaction between drug and surfactant...
  45. Jeon Y, Fong J, Riyanti E, Neilan B, Rogers P, Svenson C. Heterologous expression of the alcohol dehydrogenase (adhI) gene from Geobacillus thermoglucosidasius strain M10EXG. J Biotechnol. 2008;135:127-33 pubmed publisher
    ..In silico analysis, including phylogenetic reconstruction and protein modeling, confirmed that the thermostable enzyme from G. thermoglucosidasius is likely to belong to the NAD-Zn-dependent family of alcohol dehydrogenases...
  46. Santos J, Mijone P, Nunes G, Perez V, de Castro H. Covalent attachment of Candida rugosa lipase on chemically modified hybrid matrix of polysiloxane-polyvinyl alcohol with different activating compounds. Colloids Surf B Biointerfaces. 2008;61:229-36 pubmed
    ..The properties of the support and immobilized derivatives were also evaluated by scanning electron microscopy (SEM), energy dispersive X-ray spectroscopies and chemical composition (FTIR)...
  47. Andersson J, Simpson D, Qi M, Wang Y, Elion E. Differential input by Ste5 scaffold and Msg5 phosphatase route a MAPK cascade to multiple outcomes. EMBO J. 2004;23:2564-76 pubmed
    ..These findings reveal the versatility of scaffolds and how a single MAPK cascade mediates different outputs...
  48. Parmentier J, Pavicevic Z, Malik K. ANG II stimulates phospholipase D through PKCzeta activation in VSMC: implications in adhesion, spreading, and hypertrophy. Am J Physiol Heart Circ Physiol. 2006;290:H46-54 pubmed
  49. Brynildsen M, Liao J. An integrated network approach identifies the isobutanol response network of Escherichia coli. Mol Syst Biol. 2009;5:277 pubmed publisher
    ..The network described here could aid design and comprehension of alcohol tolerance, whereas the approach provides a general framework to characterize complex phenomena at the systems level...
  50. Gai K. Plasma-induced degradation of diphenylamine in aqueous solution. J Hazard Mater. 2007;146:249-54 pubmed
    ..The major intermediate products resulted from the degradation were identified by an HPLC analysis and a degradation path way was proposed...
  51. Weisz A, Langowski A, Meyers M, Thieken M, Ito Y. Preparative purification of tetrabromotetrachlorofluorescein and phloxine B by centrifugal counter-current chromatography. J Chromatogr. 1991;538:157-64 pubmed
    ..If this problem can be circumvented, then the counter-current chromatographic method can be extended for use with gram quantities of dye...
  52. Yoon M, Chen J. PLD regulates myoblast differentiation through the mTOR-IGF2 pathway. J Cell Sci. 2008;121:282-9 pubmed publisher
    ..Furthermore, exogenous IGF2 fully rescues the differentiation defect resulting from PLD1 knockdown. Hence, PLD1 is critically involved in skeletal myogenesis by regulating the mTOR-IGF2 pathway...
  53. Mennickent S, Nail M, Vega M, de Diego M. Quantitative determination of L-DOPA in tablets by high performance thin layer chromatography. J Sep Sci. 2007;30:1893-8 pubmed
    ..The method was fast, specific, with a good precision, and accurate for the quantitative determination of L-DOPA in tablets...