Summary: (Z)-9-Octadecenoic acid 1,2,3-propanetriyl ester.

Top Publications

  1. Choo W, Birch E. Radical scavenging activity of lipophilized products from lipase-catalyzed transesterification of triolein with cinnamic and ferulic acids. Lipids. 2009;44:145-52 pubmed publisher
    Lipase-catalyzed transesterification of triolein with cinnamic and ferulic acids using an immobilized lipase from Candida antarctica (E.C. 3.1.1...
  2. Tsuzuki W. Acidolysis between triolein and short-chain fatty acid by lipase in organic solvents. Biosci Biotechnol Biochem. 2005;69:1256-61 pubmed biocatalysts for the incorporation of short-chain fatty acids (acetic, propionic, and butyric acids) into triolein in order to produce one kind of reduced-calorie structured lipids...
  3. Kim H, Lee C, Kim H, Lee S, Son S, Kim Y, et al. Reversible MR changes in the cat brain after cerebral fat embolism induced by triolein emulsion. AJNR Am J Neuroradiol. 2004;25:958-63 pubmed
    ..A fat emulsion was made with 0.05 mL of triolein and 20 mL of normal saline and vigorous to-and-fro movement through a three-way stopcock...
  4. Pakkanen K, Duelund L, Vuento M, Ipsen J. Phase coexistence in a triolein-phosphatidylcholine system. Implications for lysosomal membrane properties. Chem Phys Lipids. 2010;163:218-27 pubmed publisher
    ..The effects of tri- and monoglycerides on phospholipid (POPC) membranes were studied using spectroscopical methods. Triolein was found to form two types of POPC-rich membranes, both with POPC or as a three-component system with ..
  5. Zhang Z, Sha X, Shen A, Wang Y, Sun Z, Gu Z, et al. Polycation nanostructured lipid carrier, a novel nonviral vector constructed with triolein for efficient gene delivery. Biochem Biophys Res Commun. 2008;370:478-82 pubmed publisher
    ..Enhanced transfection efficiency of PNLC was observed after the addition of triolein to the PNLC formulation and the transfection efficiency of the optimized PNLC was comparable to that of ..
  6. Moser H, Moser A, Hollandsworth K, Brereton N, Raymond G. "Lorenzo's oil" therapy for X-linked adrenoleukodystrophy: rationale and current assessment of efficacy. J Mol Neurosci. 2007;33:105-13 pubmed
    ..We also present current efforts to provide definitive evaluation of its clinical efficacy and discuss its possible role in the new therapeutic opportunities that will arise if newborn screening for X-ALD is validated and implemented. ..
  7. Kim Y, Kim H, Cho B, Moon T, Eun C. The study of cerebral hemodynamics in the hyperacute stage of fat embolism induced by triolein emulsion. AJNR Am J Neuroradiol. 2006;27:398-401 pubmed was to evaluate the cerebral hemodynamic change in the hyperacute stage of cerebral fat embolism induced by triolein emulsion, by using MR perfusion imaging in cat brains...
  8. Almendro V, Busquets S, Ametller E, Carbó N, Figueras M, Fuster G, et al. Effects of interleukin-15 on lipid oxidation: disposal of an oral [(14)C]-triolein load. Biochim Biophys Acta. 2006;1761:37-42 pubmed rats (100 microg/kg body weight) has important effects on the metabolic fate of an exogenous [(14)C]-triolein load, decreasing the incorporation of lipid into adipose tissue and significantly increasing the total (14)CO(2) ..
  9. Fukuwatari T, Shibata K, Iguchi K, Saeki T, Iwata A, Tani K, et al. Role of gustation in the recognition of oleate and triolein in anosmic rats. Physiol Behav. 2003;78:579-83 pubmed
    ..To examine the role of gustation for the recognition of oleate and triolein, very short-term (5-min), two-bottle preference tests were conducted in anosmic rats...

More Information


  1. Gabert L, Vors C, Louche Pelissier C, Sauvinet V, Lambert Porcheron S, Drai J, et al. 13C tracer recovery in human stools after digestion of a fat-rich meal labelled with [1,1,1-13C3]tripalmitin and [1,1,1-13C3]triolein. Rapid Commun Mass Spectrom. 2011;25:2697-703 pubmed publisher
    ..Eight subjects received a mixture of [1,1,1-(13)C3]tripalmitin and [1,1,1-(13)C3]triolein with a fat-rich meal...
  2. Wang L, Walsh M, Small D. Apolipoprotein B is conformationally flexible but anchored at a triolein/water interface: a possible model for lipoprotein surfaces. Proc Natl Acad Sci U S A. 2006;103:6871-6 pubmed
    ..We showed that two consensus AbetaS peptides of apoB bound strongly to hydrophobic interfaces [triolein/water (TO/W) and dodecane/water], were elastic, and were not pushed off the interface when the surface was ..
  3. Mitsche M, Wang L, Small D. Adsorption of egg phosphatidylcholine to an air/water and triolein/water bubble interface: use of the 2-dimensional phase rule to estimate the surface composition of a phospholipid/triolein/water surface as a function of surface pressure. J Phys Chem B. 2010;114:3276-84 pubmed publisher, egg phosphatidylcholine (EPC) was deposited from small unilamellar vesicles onto a bubble of either air or triolein (TO) formed in a low-salt buffer. The surface tension (gamma) was measured using a drop tensiometer...
  4. Kim K, Kim H, Lee S, Moon T, Lee S, Lee J, et al. Effect of triolein emulsion on the blood-testis barrier in cats. Invest Radiol. 2004;39:445-9 pubmed
    Although the blood-testis barrier (BTB) is beneficial physiologically, it acts as an obstacle to chemotherapy. We wished to determine whether a triolein emulsion could alter the permeability of the BTB in cats.
  5. Jenkins C, Mancuso D, Yan W, Sims H, Gibson B, Gross R. Identification, cloning, expression, and purification of three novel human calcium-independent phospholipase A2 family members possessing triacylglycerol lipase and acylglycerol transacylase activities. J Biol Chem. 2004;279:48968-75 pubmed acyl donor which, in the presence of mono-olein or diolein acceptors, results in the synthesis of diolein and triolein, respectively...
  6. Gormsen L, Jensen M, Nielsen S. Measuring VLDL-triglyceride turnover in humans using ex vivo-prepared VLDL tracer. J Lipid Res. 2006;47:99-106 pubmed
    ..found minor labeling of the plasma FFA (oleate) pool, which was largely attributable to coinfusion of free [14C]triolein; VLDL-TG did not contribute substantially to the plasma FFA pool...
  7. Jabusch T, Swackhamer D. Partitioning of polychlorinated biphenyls in octanol/water, triolein/water, and membrane/water systems. Chemosphere. 2005;60:1270-8 pubmed
    ..comparing the measured Kow of 12 selected polychlorinated biphenyl congeners (PCBs) with partition constants in triolein/water (Ktw) and membrane/water (Kmw) systems. Kow and Ktw were measured by the slow-stirring method...
  8. Meyers N, Wang L, Small D. Apolipoprotein C-I binds more strongly to phospholipid/triolein/water than triolein/water interfaces: a possible model for inhibiting cholesterol ester transfer protein activity and triacylglycerol-rich lipoprotein uptake. Biochemistry. 2012;51:1238-48 pubmed publisher
    ..apoC-I's behavior at hydrophobic lipoprotein surfaces, oil drop tensiometry was used to compare the binding to triolein/water (TO/W) and palmitoyloleoylphosphatidylcholine/triolein/water (POPC/TO/W) interfaces...
  9. Kim H, Lee J, Lee C, Lee S, Moon T, Cho B, et al. Experimental cerebral fat embolism: embolic effects of triolein and oleic acid depicted by MR imaging and electron microscopy. AJNR Am J Neuroradiol. 2002;23:1516-23 pubmed
    ..We evaluated the hyperacute embolic effects of triolein and oleic acid in cat brains by using MR imaging and electron microscopy...
  10. Lu Y, Wang Z, Huckins J. Review of the background and application of triolein-containing semipermeable membrane devices in aquatic environmental study. Aquat Toxicol. 2002;60:139-53 pubmed
    ..on passive in situ samplers for aquatic environments but focuses on the development and application of the triolein-containing semipermeable membrane device in aquatic environmental monitoring...
  11. van Geel B, Assies J, Haverkort E, Koelman J, Verbeeten B, Wanders R, et al. Progression of abnormalities in adrenomyeloneuropathy and neurologically asymptomatic X-linked adrenoleukodystrophy despite treatment with "Lorenzo's oil". J Neurol Neurosurg Psychiatry. 1999;67:290-9 pubmed
    ..Furthermore, the oil often induced adverse effects. Therefore, it is advocated that "Lorenzo's oil" should not be prescribed routinely to patients with X-ALD who already have neurological deficits. ..
  12. Li C, Zhang Y, Li S, Wang G, Xu C, Deng Y, et al. Mechanism of formation of trans fatty acids under heating conditions in triolein. J Agric Food Chem. 2013;61:10392-7 pubmed publisher
    ..b>Triolein (18:1,9c) was heated at two range temperatures (130, 160, 190, 220 °C and 135, 140, 145, 150, 155 °C) and ..
  13. Iannone A, Petroni A, Murru E, Cordeddu L, Carta G, Melis M, et al. Impairment of 8-iso-PGF(2ALPHA) isoprostane metabolism by dietary conjugated linoleic acid (CLA). Prostaglandins Leukot Essent Fatty Acids. 2009;80:279-87 pubmed publisher
    ..IP formation and/or metabolism and to explain the mechanism, we challenged rats supplemented with CLA or with triolein (as a control fatty acid), with a single dose of carbon tetrachloride (CCl(4)) or of bacterial lipopolysaccharide ..
  14. Salis A, Pinna M, Monduzzi M, Solinas V. Biodiesel production from triolein and short chain alcohols through biocatalysis. J Biotechnol. 2005;119:291-9 pubmed
    ..namely Candida antarctica B, Rizhomucor miehei, and Pseudomonas cepacia, were tested towards the reaction between triolein and butanol to produce butyl oleate...
  15. Moser H. Therapy of X-linked adrenoleukodystrophy. NeuroRx. 2006;3:246-53 pubmed
    ..Application of these interventions requires careful assessment of the patients' phenotype, which often changes over time. Family screening provides important opportunities for disease prevention...
  16. Lee J, Eun C, Kim Y, Kim H, Jung Y, Jae S, et al. The steroid effect on the blood-ocular barrier change induced by triolein emulsion as seen on contrast-enhanced MR images. Korean J Radiol. 2008;9:205-11 pubmed publisher
    The purpose of this study is to evaluate the effect of dexamethasone on the damaged blood-ocular barrier caused by triolein emulsion, using contrast-enhanced MR imaging. An emulsion of 0...
  17. Ritz M, Fraser R, Di Matteo A, Greville H, Butler R, Cmielewski P, et al. Evaluation of the 13C-triolein breath test for fat malabsorption in adult patients with cystic fibrosis. J Gastroenterol Hepatol. 2004;19:448-53 pubmed
    ..Breath tests using substrates labeled with 13C meet these conditions. The 14C-triolein breath test is sensitive and specific for measuring fat malabsorption, but involves radiation exposure...
  18. Ru J, Liu H, Qu J, Wang A, Dai R, Wang Z. Selective removal of organochlorine pesticides (OCPs) from aqueous solution by triolein-embedded composite adsorbent. J Environ Sci Health B. 2007;42:53-61 pubmed
    ..The adsorbent was composed of the supporting activated carbon and the surrounding triolein-embedded cellulose acetate membrane...
  19. Senior K. Lorenzo's oil may help to prevent ALD symptoms. Lancet Neurol. 2002;1:468 pubmed
  20. Mitchell D, Rodriguez J, Carriere F, Krieger N. Determination of the quantitative stereoselectivity fingerprint of lipases during hydrolysis of a prochiral triacylglycerol. J Biotechnol. 2008;135:168-73 pubmed publisher
    ..determine the stereoselectivity fingerprint of several lipases during the hydrolysis of the prochiral substrate triolein. Our method opens up the possibility of correlating quantitative fingerprints with structural information, in the ..
  21. Kruse Elliott K, Olson N. Role of leukotrienes during oleic acid-induced lung injury in pigs. J Appl Physiol (1985). 1990;68:1360-7 pubmed] + oleic acid (10 h-1), or triolein (20 were infused intravenously into anesthetized pigs...
  22. Jun J, Shin M, Yao Q, Bevans Fonti S, Poole J, Drager L, et al. Acute hypoxia induces hypertriglyceridemia by decreasing plasma triglyceride clearance in mice. Am J Physiol Endocrinol Metab. 2012;303:E377-88 pubmed publisher
    ..This degree of hypoxia rapidly and reversibly delayed TG clearance while decreasing [(3)H]triolein-labeled Intralipid uptake in brown adipose tissue and WAT...
  23. Ehling S, Hengel M, Shibamoto T. Formation of acrylamide from lipids. Adv Exp Med Biol. 2005;561:223-33 pubmed
    ..The results of the present study suggest that acrylamide forms in asparagine-rich foods during deep fat frying in the absence reducing sugars. ..
  24. Xu Y, Wang Z, Ke R, Khan S. Accumulation of organochlorine pesticides from water using triolein embedded cellulose acetate membranes. Environ Sci Technol. 2005;39:1152-7 pubmed
    A new type of composite membrane, triolein embedded cellulose acetate membrane (TECAM), was produced by embedding triolein drops in the matrix of cellulose acetate polymers...
  25. Rehan V, Torday J. Hyperoxia augments pulmonary lipofibroblast-to-myofibroblast transdifferentiation. Cell Biochem Biophys. 2003;38:239-50 pubmed
    ..These results suggest that exposure to hyperoxia (95% O2) augments the transdifferentiation of pulmonary lipofibroblasts to myofibroblasts. ..
  26. Miyoshi Y, Sakai N, Hamada Y, Tachibana M, Hasegawa Y, Kiyohara Y, et al. Clinical aspects and adrenal functions in eleven Japanese children with X-linked adrenoleukodystrophy. Endocr J. 2010;57:965-72 pubmed
    ..Addison's form might be overlooked in Japan; therefore, X-ALD should be suspected in patients with adrenocortical insufficiency. ..
  27. Tao Y, Xue B, Yao S, Deng J, Gui Z. Triolein embedded cellulose acetate membrane as a tool to evaluate sequestration of PAHs in lake sediment core at large temporal scale. Environ Sci Technol. 2012;46:3851-8 pubmed publisher
    ..A biomimetic tool, triolein embedded cellulose acetate membrane (TECAM), was therefore tested to evaluate sequestration of six PAHs with ..
  28. Tao Y, Zhang S, Wang Z, Christie P. Predicting bioavailability of PAHs in field-contaminated soils by passive sampling with triolein embedded cellulose acetate membranes. Environ Pollut. 2009;157:545-51 pubmed publisher
    b>Triolein embedded cellulose acetate membrane (TECAM) was used for passive sampling of the fraction of naphthalene, phenanthrene, pyrene and benzo[a]pyrene in 18 field-contaminated soils...
  29. Foltz M, Maljaars J, Schuring E, van der Wal R, Boer T, Duchateau G, et al. Intragastric layering of lipids delays lipid absorption and increases plasma CCK but has minor effects on gastric emptying and appetite. Am J Physiol Gastrointest Liver Physiol. 2009;296:G982-91 pubmed publisher
    ..An escalating-dose study should determine whether this could have implications for the development of weight-control foods. ..
  30. Patel S, Suresh S, Weintroub H, Brady R, Pentchev P. Impaired cholesterol esterification in primary brain cultures of the lysosomal cholesterol storage disorder (LCSD) mouse mutant. Biochem Biophys Res Commun. 1987;143:233-40 pubmed
    ..These observations on LCSD mutant brain cells indicate that the defect in cholesterol esterification is closely related to the primary genetic defect and is expressed in neuroglial cells in culture. ..
  31. Noh S, Koo S. Intraduodenal infusion of lysophosphatidylcholine restores the intestinal absorption of vitamins A and E in rats fed a low-zinc diet. Exp Biol Med (Maywood). 2001;226:342-8 pubmed
    ..0 ml/hr for 8 hr with a lipid emulsion containing retinol, alphaTP, and 14C-labeled triolein (14C-oleic acid) with or without 1-oleoyl-2-hydroxy phosphatidylcholine (lysoPC) in 24 ml of PBS (pH 6.5)...
  32. Lanser A, Manthey L, Hou C. Regioselectivity of new bacterial lipases determined by hydrolysis of triolein. Curr Microbiol. 2002;44:336-40 pubmed
    ..ARS Culture Collection have been characterized on the basis of their positional specificity for triglycerides (triolein)...
  33. Heinis L, Highland T, Mount D. Method for testing the aquatic toxicity of sediment extracts for use in identifying organic toxicants in sediments. Environ Sci Technol. 2004;38:6256-62 pubmed
    ..This involves transferring solvent extracts of sediment into triolein and then placing the mixture inside low-density polyethylene dialysis tubing in a configuration similar to ..
  34. Abbasi S, Kajimoto K, Harashima H. Elimination of the biphasic pharmacodynamics of 15d-PGJ2 by controlling its release from a nanoemulsion. Int J Nanomedicine. 2016;11:2685-94 pubmed publisher
    ..The 15d-PGJ2 was encapsulated in the NE composed of triolein/distearoyl phosphatidylcholine/Tween 80 at a high encapsulation ratio (>83%)...
  35. Damodaran S, Sengupta T. Dynamics of competitive adsorption of alphas-casein and beta-casein at planar triolein-water interface: evidence for incompatibility of mixing in the interfacial film. J Agric Food Chem. 2003;51:1658-65 pubmed
    Competitive adsorption of alpha(s)-casein and beta-casein from a bulk solution mixture to the triolein-water interface has been studied...
  36. Ledford A, Weinberg R, Cook V, Hantgan R, Shelness G. Self-association and lipid binding properties of the lipoprotein initiating domain of apolipoprotein B. J Biol Chem. 2006;281:8871-6 pubmed
    ..1H multimers spontaneously dissociated and bound to the interface of naked and phospholipid-coated triolein droplets...
  37. Liu H, Qu J, Dai R, Ru J, Wang Z. A biomimetic absorbent for removal of trace level persistent organic pollutants from water. Environ Pollut. 2007;147:337-42 pubmed
    A novel biomimetic absorbent containing the lipid triolein was developed for removing persistent organic pollutants (POPs) from water. The structural characteristics of the absorbent were obtained by SEM and a photoluminescence method...
  38. Gireesh T, Sudhakaran P. In vitro uptake of ?-carotene by human exfoliated colonic epithelial cells. Int J Food Sci Nutr. 2009;60:109-18 pubmed publisher
    ..The uptake was found to increase in the presence of primary bile acids such as deoxy cholate, lipids such as triolein and lecithin in a concentration-dependent manner...
  39. Gorshkova I, Kypreos K, Gantz D, Zannis V, Atkinson D. Biophysical properties of apolipoprotein E4 variants: implications in molecular mechanisms of correction of hypertriglyceridemia. Biochemistry. 2008;47:12644-54 pubmed publisher
    ..The slightly altered structural properties of apoE4-mut2 are associated with slightly reduced binding of this protein to TG-rich lipoprotein particles and milder hypertriglyceridemia as compared with WT apoE4. ..
  40. Luo Y, Shelly L, Sand T, Chang G, Jiang X. Identification and characterization of dual inhibitors for phospholipid transfer protein and microsomal triglyceride transfer protein. J Pharmacol Exp Ther. 2010;335:653-8 pubmed publisher
    ..We conclude that MTP and PLTP may work coordinately in the process of hepatic apoB assembly and secretion. To avoid liver toxicity mediated by MTP inhibition, selective PLTP inhibitors should be pursued. ..
  41. Chang I, Kim I, Kang S, Hou C, Kim H. Production of 7, 10-dihydroxy-8(E)-octadecenoic acid from triolein via lipase induction by Pseudomonas aeruginosa PR3. Appl Microbiol Biotechnol. 2007;74:301-6 pubmed
    ..However, it is possible to utilize triacylglycerides, specifically triolein containing three oleic groups, as a substrate by microbial enzyme system involved in HFA production from oleic ..
  42. Liao H, Tsai W, Chang S, Shieh C. Application of solvent engineering to optimize lipase-catalyzed 1,3-diglyacylcerols by mixture response surface methodology. Biotechnol Lett. 2003;25:1857-61 pubmed
    ..The optimum yield (approximately 40%) of 1,3-DAG synthesis was obtained with n-hexane/octane (1:1, v/v). ..
  43. Hermansyah H, Wijanarko A, Kubo M, Shibasaki Kitakawa N, Yonemoto T. Rigorous kinetic model considering positional specificity of lipase for enzymatic stepwise hydrolysis of triolein in biphasic oil-water system. Bioprocess Biosyst Eng. 2010;33:787-96 pubmed publisher
    ..This model was applied to the experimental results for triolein hydrolysis using suspended Porcine pancreatic lipase (an sn-1,3 specific lipase) and Candida rugosa lipase (a non-..
  44. Moser H, Raymond G, Dubey P. Adrenoleukodystrophy: new approaches to a neurodegenerative disease. JAMA. 2005;294:3131-4 pubmed
    ..Neonatal screening is likely to become available, and a wider awareness of X-ALD and its various modes of presentation permit new proactive approaches to this distressing disorder. ..
  45. Ke R, Luo J, Sun L, Wang Z, Spear P. Predicting bioavailability and accumulation of organochlorine pesticides by Japanese medaka in the presence of humic acid and natural organic matter using passive sampling membranes. Environ Sci Technol. 2007;41:6698-703 pubmed
    ..Here, the suitability of using triolein-embedded cellulose acetate membrane (TECAM) as a biomimetic surrogate to assess the bioavailability of ..
  46. Jandacek R, Zheng S, Yang Q, Tso P. Rapid clearance of hexachlorobenzene from chylomicrons. Lipids. 2004;39:993-5 pubmed
    ..were obtained from mesenteric lymph of rats that were intraduodenally given 14C-hexachlorobenzene and 3H-triolein. The labeled chylomicrons were injected intravenously into recipient rats, and the clearance of isotopes was ..
  47. Følsvik N, Brevik E, Berge J. Monitoring of organotin compounds in seawater using semipermeable membrane devices (SPMDs)--tentative results. J Environ Monit. 2000;2:281-4 pubmed
    ..As the membranes are able to accumulate the organotins from the water it will be possible to locate lower concentrations than with direct analyses of water samples. ..
  48. Bayés García L, Calvet T, Cuevas Diarte M, Ueno S, Sato K. Crystallization and transformation of polymorphic forms of trioleoyl glycerol and 1,2-dioleoyl-3-rac-linoleoyl glycerol. J Phys Chem B. 2013;117:9170-81 pubmed publisher
  49. Robinson N, MacGibbon A. Determination of the conjugated linoleic acid-containing triacylglycerols in New Zealand bovine milk fat. Lipids. 2000;35:789-96 pubmed
    ..substantially due to CLA-TAG (chromatography of some representative TAG devoid of CLA, such as tripalmitin and triolein, showed poor responses at 233 nm, 1/800th that of CLA-TAG)...
  50. Yorifuji T. [Adrenoleukodystrophy, adrenomyeloneuropathy]. Nihon Rinsho. 2006;Suppl 1:582-5 pubmed
  51. Hsieh J, Longuet C, Maida A, Bahrami J, Xu E, Baker C, et al. Glucagon-like peptide-2 increases intestinal lipid absorption and chylomicron production via CD36. Gastroenterology. 2009;137:997-1005, 1005.e1-4 pubmed publisher
    ..cluster of differentiation 36/fatty acid translocase (CD36), and induced intestinal absorption of [(3)H]triolein. The ability of GLP-2 to increase intestinal lipoprotein production was lost in Cd36(-/-) mice...
  52. Ledford A, Cook V, Shelness G, Weinberg R. Structural and dynamic interfacial properties of the lipoprotein initiating domain of apolipoprotein B. J Lipid Res. 2009;50:108-15 pubmed publisher
    ..1 mN/m vs. 22.8 mN/m). Oil drop tensiometry revealed that both proteins bound rapidly to the hydrophobic triolein/water interface, reducing interfacial tension by approximately 20 mN/m...
  53. Kudchodkar B, Lacko A, Dory L, Fungwe T. Dietary fat modulates serum paraoxonase 1 activity in rats. J Nutr. 2000;130:2427-33 pubmed], whereas the remaining three groups received the modified control diet supplemented with (15 g/100 g diet) triolein, tripalmitin or fish oil, respectively...