fetal research

Summary

Alias: fetal experimentation
Summary: Experimentation on, or using the organs or tissues from, a human or other mammalian conceptus in the postembryonic period, after the major structures have been outlined. In humans, this corresponds to the period from the third month after fertilization until birth.

Webpages

  1. irb guidebook: chapter vi special classes of subjects
    www.hhs.gov/ohrp/irb/irb_chapter6.htm
  2. ucsf animal care & use program - occupational health & safety: sheep or goats
    www.iacuc.ucsf.edu/Safe/awOhsSheepGoat.asp
  3. us code: title 42,289g. fetal research
    www4.law.cornell.edu/uscode/html/uscode42/usc_sec_42_0000028 ...
  4. usccb - pro-life activities - practical problems with embryonic stem cells
    www.usccb.org/prolife/issues/bioethic/stemcell/obstacles5100 ...
  5. sulair: research quick start guides: bioethics
    www-sul.stanford.edu/guides/bioethic.html
  6. sulair: research quick start guides: bioethics
    library.stanford.edu/guides/bioethic.html
  7. twin reversed arterial perfusion sequence and bipolar cord coagulation for acardiac/acephalic twins : fetal diagnosis and treatment - children's hospital of philadelphia
    www.chop.edu/consumer/jsp/division/generic.jsp?id=81174
  8. chop hydrocephalus publications : fetal diagnosis and treatment - children's hospital of philadelphia
    www.chop.edu/consumer/jsp/division/generic.jsp?id=81687

Research Grants

  1. Maternal Lifestyle Study
    Seetha Shankaran; Fiscal Year: 2005
  2. MULTICENTER NETWORK OF MATERNAL-FETAL MEDICINE UNITS
    Robert S Egerman; Fiscal Year: 2003
  3. EXTRAMURAL RESEARCH FACILITIES CONSTRUCTION
    DANIEL A WALZ; Fiscal Year: 2003
  4. Johns Hopkins AIDS Clinical Trials Unit
    Charles W Flexner; Fiscal Year: 2007
  5. Johns Hopkins AIDS Clinical Trials Unit
    Charles W Flexner; Fiscal Year: 2008

Publications

  1. Rights of embryo and foetus in private law
    Timothy Stoltzfus Jost
    Washington and Lee University School of Law, USA
    Am J Comp Law 50:633-46
  2. Embryonic stem cell research: one small step for science or one giant leap back for mankind?
    Consuelo G Erwin
    Univ Ill Law Rev 2003:211-43
  3. Stem cell terminology: practical, theological and ethical implications
    Laura Shanner
    John Dossetor Health Ethics Centre, University of Alberta, Edmonton, Alberta, Canada
    Health Law Rev 11:62-6
  4. John Paul II on the language empowering the culture of death
    William Brennan
    School of Social Service, Saint Louis University, St. Louis, Missouri, USA
    Natl Cathol Bioeth Q 3:731-46
  5. Reasoning about embryos, cloning and stem cells: let's get more clear and distinct
    Malcolm Parker
    Ethics and Professional Development, School of Medicine, University of Queensland, Australia
    Monash Bioeth Rev 22:8-17
  6. [The revised Japanese pharmaceutical law and research ethics: risk-benefit assessment of fetal stem cell research]
    Chieko Kurihara
    Sato Jitsugyo Ebisu Bldg 4F, 1 11 2 Ebisu, Shibuya ku, Tokyo 150 0013, Japan
    Yakugaku Zasshi 123:91-106
  7. Stem cells and kidney diseases
    M R Abbattista
    Division of Nephrology, Dialysis and Transplantation, University of Bari, Polyclinic, Bari, Italy
    Minerva Med 95:411-8
  8. Ethics and fetal research
    Sidney Callahan
    St. John's University, New York, USA
    Med Ethics 10:10-1
  9. Ethics of maternal-fetal surgery
    Frank A Chervenak
    New York Presbyterian Hospital, 525 East 68th Street J130, New York, NY 10021, USA
    Semin Fetal Neonatal Med 12:426-31
  10. Washington insider
    Richard M Doerflinger
    Natl Cathol Bioeth Q 6:413-20

Scientific Experts

Detail Information

Webpages11

  1. irb guidebook: chapter vi special classes of subjects
    www.hhs.gov/ohrp/irb/irb_chapter6.htm
  2. ucsf animal care & use program - occupational health & safety: sheep or goats
    www.iacuc.ucsf.edu/Safe/awOhsSheepGoat.asp
  3. us code: title 42,289g. fetal research
    www4.law.cornell.edu/uscode/html/uscode42/usc_sec_42_0000028 ...
  4. usccb - pro-life activities - practical problems with embryonic stem cells
    www.usccb.org/prolife/issues/bioethic/stemcell/obstacles5100 ...
  5. sulair: research quick start guides: bioethics
    www-sul.stanford.edu/guides/bioethic.html
  6. sulair: research quick start guides: bioethics
    library.stanford.edu/guides/bioethic.html
  7. twin reversed arterial perfusion sequence and bipolar cord coagulation for acardiac/acephalic twins : fetal diagnosis and treatment - children's hospital of philadelphia
    www.chop.edu/consumer/jsp/division/generic.jsp?id=81174
  8. chop hydrocephalus publications : fetal diagnosis and treatment - children's hospital of philadelphia
    www.chop.edu/consumer/jsp/division/generic.jsp?id=81687

Research Grants5

  1. Maternal Lifestyle Study
    Seetha Shankaran; Fiscal Year: 2005
    ..The Division of Maternal-Fetal Medicine at Wayne State is currently a member of the NICHD Multicenter Materna/-Fetal Research Network (MFM)...
  2. MULTICENTER NETWORK OF MATERNAL-FETAL MEDICINE UNITS
    Robert S Egerman; Fiscal Year: 2003
    ..of Tennessee, Memphis, and the Department of Obstetrics and Gynecology are committed to collaborative Maternal-Fetal research as documented by listed publications and the enclosed letters of commitment...
  3. EXTRAMURAL RESEARCH FACILITIES CONSTRUCTION
    DANIEL A WALZ; Fiscal Year: 2003
    ..To maintain and enhance national leadership role in reproductive health and pregnancy-related maternal-fetal research and research training over the next 30 years, plans are completely renovating the Mort Center...
  4. Johns Hopkins AIDS Clinical Trials Unit
    Charles W Flexner; Fiscal Year: 2007
    ..therapeutics, neurology, hepatitis virus and HIV co-infection, and pediatric, adolescent, and maternal-fetal research. The investigators in this proposed CTU have authored over 1,000 published papers related to HIV infection, >..
  5. Johns Hopkins AIDS Clinical Trials Unit
    Charles W Flexner; Fiscal Year: 2008
    ..therapeutics, neurology, hepatitis virus and HIV co-infection, and pediatric, adolescent, and maternal-fetal research. The investigators in this proposed CTU have authored over 1,000 published papers related to HIV infection, >..

Publications59

  1. Rights of embryo and foetus in private law
    Timothy Stoltzfus Jost
    Washington and Lee University School of Law, USA
    Am J Comp Law 50:633-46
  2. Embryonic stem cell research: one small step for science or one giant leap back for mankind?
    Consuelo G Erwin
    Univ Ill Law Rev 2003:211-43
    ..Such a prohibition will fulfill the societal policy choice of protecting potential life and vulnerable human subjects...
  3. Stem cell terminology: practical, theological and ethical implications
    Laura Shanner
    John Dossetor Health Ethics Centre, University of Alberta, Edmonton, Alberta, Canada
    Health Law Rev 11:62-6
    ....
  4. John Paul II on the language empowering the culture of death
    William Brennan
    School of Social Service, Saint Louis University, St. Louis, Missouri, USA
    Natl Cathol Bioeth Q 3:731-46
  5. Reasoning about embryos, cloning and stem cells: let's get more clear and distinct
    Malcolm Parker
    Ethics and Professional Development, School of Medicine, University of Queensland, Australia
    Monash Bioeth Rev 22:8-17
    ..Decisions about ethically and legally acceptable reproductive technologies ultimately depend on support for one metaphysical grounding at the expense of another. This should be acknowledged, as should its implications for policy...
  6. [The revised Japanese pharmaceutical law and research ethics: risk-benefit assessment of fetal stem cell research]
    Chieko Kurihara
    Sato Jitsugyo Ebisu Bldg 4F, 1 11 2 Ebisu, Shibuya ku, Tokyo 150 0013, Japan
    Yakugaku Zasshi 123:91-106
    ..Conscientious reflection is necessary to reach a public consensus on which types of human material can be utilized as research or pharmaceutical resources...
  7. Stem cells and kidney diseases
    M R Abbattista
    Division of Nephrology, Dialysis and Transplantation, University of Bari, Polyclinic, Bari, Italy
    Minerva Med 95:411-8
    ..In fact, SCs may provide innovative methods for drug delivery, immunotherapy, tissue regenerative or replacement engineering...
  8. Ethics and fetal research
    Sidney Callahan
    St. John's University, New York, USA
    Med Ethics 10:10-1
  9. Ethics of maternal-fetal surgery
    Frank A Chervenak
    New York Presbyterian Hospital, 525 East 68th Street J130, New York, NY 10021, USA
    Semin Fetal Neonatal Med 12:426-31
    ..The ethical framework is illustrated by the example of fetal surgery for spina bifida...
  10. Washington insider
    Richard M Doerflinger
    Natl Cathol Bioeth Q 6:413-20
  11. Ethics of research and the pregnant patient
    Frank A Chervenak
    Department of Obstetrics and Gynecology, New York Presbyterian Hospital, 525 East 68th Street J130, New York, NY 10021, USA
    Curr Womens Health Rep 3:505-9
    ..The implications of this concept for the ethics of fetal research are identified...
  12. Ethical issues in the management of pregnancies complicated by fetal anomalies
    Frank A Chervenak
    Department of Obstetrics and Gynecology, The New York Presbyterian Hospital, Weill Medical College of Cornell University, 525 East 68th Street J130, New York, NY 10025, USA
    Obstet Gynecol Surv 58:473-83
    ..guidance is given for the physician's role in counseling pregnant women about aggressive management, termination of pregnancy, selective termination of multifetal pregnancies, nonaggressive management, cephalocentesis, and fetal research.
  13. Stem cells: promises versus limitations
    Despoina M Choumerianou
    Department of Pediatric Hematology Oncology, University Hospital of Heraklion, University of Crete, Heraklion, Crete, Greece
    Tissue Eng Part B Rev 14:53-60
    ..Nevertheless, it raises ethical concerns that need to be addressed before the use of stem cells in clinical practice...
  14. The fetus as our patient: the confluence of faith and science in the care of the unborn
    Byron C Calhoun
    University of Illinois at Chicago, USA
    Linacre Q 72:189-211
  15. Maternal-fetal research and human research protections policy
    Angelique M Reitsma
    Center for Biomedical Ethics, PO Box 800758, University of Virginia, Charlottesville, VA 22908 0758, USA
    Clin Perinatol 30:141-53
    ..Those responsible for reviewing study protocols will have to be especially careful when examining the new version of DHHS regulations as they apply to future studies in the field of MFS...
  16. Down for the count? State regulation of aborted fetal tissue research
    Rachel Keener
    Wake Forest Law Rev 37:217-37
  17. Spontaneous miscarriages as source of fetal stem cells
    Maria Michejda
    Protocell, LLC, North Potomac, Maryland, USA
    Natl Cathol Bioeth Q 2:401-11
  18. An Islamic perspective on human genetic and reproductive technologies
    H Hathout
    Board of Trustees, Islamic Organization for Medical Sciences, Kuwait
    East Mediterr Health J 12:S22-8
    ..This paper gives an Islamic perspective on some of these advances, including abortion, in vitro fertilization, genetic engineering, cloning and stem cell research...
  19. Stem cell research
    Elliot N Dorff
    University of Judaism, Los Angeles, CA, USA
    Conserv Jud 55:3-29
  20. Human embryo and early fetus research
    H Ostrer
    Human Genetics Program, Department of Pediatrics, New York University School of Medicine, New York, NY 10016, USA
    Clin Genet 70:98-107
    ..In this article, we review these applications. We also discuss when and how to study human embryo and early fetuses and some of the regulations of this research...
  21. An ethical framework for fetal research
    Frank A Chervenak
    Department of Obstetrics and Gynecology, New York Presbyterian Hospital, Weill Medical College of Cornell University, NY, USA
    Med Ethics 10:1-2
  22. Bioethical challenges for the church
    John Nienstedt
    Origins 32:676-82
  23. Bone tissue engineering using foetal cell therapy
    Dominique P Pioletti
    Laboratoire de Biomécanique en Orthopédie EPFL HOSR, Institut de Biomécanique Translationnelle, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland
    Swiss Med Wkly 136:557-60
    ..Finally, foetal cells used specifically for bone tissue engineering are characterised and potentially interesting therapeutic options are proposed...
  24. [Science and law in assisted reproductive medicine -- two sides of the same token]
    H Hepp
    Gynakol Geburtshilfliche Rundsch 43:1-5
    ..The technically feasible frequently surpasses what can or should ethically and legally be made possible...
  25. [Dutch Institute for Health Care Improvement's standard code of practice entitled, "Donation of fetal tissue"]
    J M van den Boer van den Berg
    Erasmus Medisch Centrum, afd Klinische Genetica, Rotterdam
    Ned Tijdschr Geneeskd 147:1351-5
    ..As a general rule, foetal tissue should be stored anonymously. Adjustment of the abortion method in view of the intended scientific research is not permitted...
  26. [Comments on the Dutch Institute for Health Care Improvement's standard code of practice entitled, "Donation of fetal tissue"]
    G M de Wert
    Universiteit Maastricht, Instituut voor Gezondheidsethiek, Postbus 616, 6200 MD Maastricht
    Ned Tijdschr Geneeskd 147:1341-3
    ....
  27. Human cloning: Eastern Mediterranean Region perspective
    M Abdur Rab
    WHO Sudan, Khartoum, Sudan
    East Mediterr Health J 12:S29-37
    ..There is an urgent need for Muslim scholars to discuss the issue of stem cell research and cloning rationally; such dialogue will not only consider the scientific merits but also the moral, ethical and legal implications...
  28. Bioethics and the future of humanity
    Sam Brownback
    United States Senate, USA
    Natl Cathol Bioeth Q 6:423-30
  29. Codes of perinatal ethics: an international perspective
    Joseph G Schenker
    Department of Obstetrics and Gynecology, Hebrew University, Hadassah Medical Center, PO Box 12000, Jerusalem IL 91120, Israel
    Clin Perinatol 30:45-65
    ..For these committees to be of full advantage, they must convene promptly as issues arise so as not to delay medical advances from being implemented...
  30. The ethics of HEK 293
    Alvin Wong
    Natl Cathol Bioeth Q 6:473-95
  31. Complicity, fetal tissue, and vaccines
    Alexander R Pruss
    Natl Cathol Bioeth Q 6:461-70
  32. A brief history of human diploid cell strains
    Rene Leiva
    Natl Cathol Bioeth Q 6:443-51
  33. Cooperation with past evil and use of cell-lines derived from aborted fetuses
    Alexander R Pruss
    Department of Philosophy, Georgetown University, Washington, DC, USA
    Linacre Q 71:335-50
  34. Could artificial wombs end the abortion debate?
    Christopher Kaczor
    Loyola Marymount University, Los Angeles, CA, USA
    Natl Cathol Bioeth Q 5:283-301
  35. UK opens embryonic stem cell bank
    Stephen Pincock
    Lancet 363:1778
  36. [Stem cell colloquy: conclusion]
    Maurice Tubiana
    Centre Antoine Béclère, Faculté de Médecine, 45, rue des Saints Pères, 75006 Paris, France
    C R Biol 325:1065-71
    ..The scientific and medical problems are many, and the solutions will be long and difficult to find. Regenerative medicine opens important avenues for research, but medical progress will be slow...
  37. Ethical aspects of use of fetal/embryonic cells in treatment and research
    H Watt
    Linacre Centre for Healthcare Ethics, London, United Kingdom
    Zentralbl Neurochir 66:75-8
    ..Irrespective of the medical benefits for which we may be hoping, we cannot relieve the suffering of one human individual by exploiting another...
  38. Stem cells: potential cures or abortion lures?
    Valerie J Janosky
    DePaul J Health Care Law 6:111-57
  39. "Of uncertain viability." The new federal rules for fetal and neonatal research
    Jonathan D Moreno
    Hastings Cent Rep 32:47-8
  40. In vivo model to determine fetal-cell enrichment efficiency of novel noninvasive prenatal diagnosis methods
    S Ponnusamy
    Diagnostic Biomarker Discovery Laboratory, Division of Maternal and Fetal Medicine, Department of Obstetrics and Gynecology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore
    Prenat Diagn 28:494-502
    ..65). CONCLUSION: Our data demonstrate that maternal blood obtained immediately post-TOP would be a good in vivo model to determine the enrichment efficiency of novel protocols and methods for noninvasive prenatal diagnosis...
  41. Fetal cells in maternal tissue following pregnancy: what are the consequences?
    Kirby L Johnson
    Division of Genetics, Department of Pediatrics, Tufts New England Medical Center, Box 394, 750 Washington Street Boston, MA 02111, USA
    Hum Reprod Update 10:497-502
    ....
  42. The moral, ethical, and legal controversy surrounding pluripotent stem cell research
    Kathleen Doody
    Loyola Law Rev 48:267-326
  43. Studies provoke shock and horror
    Andy Coghlan
    New Sci 179:19
  44. [Research on human fetuses and embryos: on the position of the Ethics National Commission]
    J Martin
    Rev Med Suisse 2:479-81
  45. [The new provocation of Professor Claude Sureau]
    Jean-Yves Nau
    Rev Med Suisse 1:2626
  46. What British women say matters to them about donating an aborted fetus to stem cell research: a focus group study
    Naomi Pfeffer
    London Metropolitan University, 62 66 Highbury Grove, London N5 2AD, United Kingdom
    Soc Sci Med 66:2544-54
    ..By the end of the focus groups, participants had co-produced a tendency to refuse to donate aborted fetuses...
  47. International stem cell research considerations
    Heiner Westphal
    Laboratory of Mammalian Genes and Development, National Institute of Child Health and Human Development, National Institutes Department of Health and Human Services, of Health, Bethesda, Maryland 20892 2790, USA
    C R Biol 325:1045-8
    ....
  48. Controversy on adult stem-cell plasticity and rules governing the use of fetal tissue in China
    Pei-hsien Tang
    J Lab Clin Med 143:199-200
  49. [The status of the fetus-- influence of its consideration on medical and technical developments]
    J Martin
    Rev Med Suisse 1:1456-8
  50. Novel methods for delivery of cell-based therapies
    M Cecilia Crisanti
    Department of Pediatric Surgery, St Christopher s Hospital For Children, Drexel University College of Medicine, Philadelphia, Pennsylvania, USA
    J Surg Res 146:3-10
    ..This represents the first step toward translational research with site-specific delivery for a cell-based therapeutic approach toward PH and similar pulmonary diseases...
  51. Assessing fetal nerve cell grafts in Parkinson's disease
    Heiko Braak
    Nat Med 14:483-5
  52. The beginning of human life and its modern scientific assessment
    A Kurjak
    Department of Obstetrics and Gynecology, Medical School University of Zagreb, Sveti Duh Hospital, Sveti Duh 64, 10000 Zagreb, Croatia
    Clin Perinatol 30:27-44, v-vi
    ..The question of when human life begins requires the essential aid of different forms of knowledge. Here we become involved in the juncture between science and religion, which needs to be carefully explored...
  53. Xenotransplantation: an ethical evaluation giving special consideration to animal ethical aspects
    Andrea Arz de Falco
    Leiterin Abteilung Biomedizin, Bundesamt für Gesundheit, Bern, Switzerland
    Swiss Med Wkly 137:138S-139S
  54. Governmental, national, international agency and other initiatives to advance the application of cellular therapies
    J G Sharp
    Cytotherapy 7:315-6
  55. Ultrastructural and metabolic changes in osteoblasts exposed to uranyl nitrate
    D R Tasat
    Escuela de Ciencia y Tecnología, Universidad Nacional de San Martín, M de Irygoyen 3100, San Martín 1650, Pcia de Bs As, Argentina
    Arch Toxicol 81:319-26
    ..controls. Our results show that UN modifies osteoblast cell metabolism by increasing ROS generation and reducing APh activity, suggesting that ROS may play a more complex role in cell physiology than simply causing oxidative damage...
  56. Topography of the pelvic autonomic nervous system and its potential impact on surgical intervention in the pelvis
    B Baader
    Department of Anatomy and Cellular Neurobiology, University of Ulm, Ulm, Germany
    Clin Anat 16:119-30
    ....
  57. Autocrine growth factor production by fetal, keloid, and normal dermal fibroblasts
    Matthew M Hanasono
    Wound Healing and Tissue Engineering Laboratory, Division of Otolaryngology Head and Neck Surgery, Stanford University Medical Center, Stanford, CA, USA
    Arch Facial Plast Surg 5:26-30
    ..This model provides information that may allow us to better treat and prevent undesirable scarring...
  58. Use of human fetal tissue for biomedical research in Australia, 1994-2002
    Bernard E Tuch
    Diabetes Transplant Unit, Prince of Wales Hospital, Randwick, NSW 2031, Australia
    Med J Aust 179:547-50
    ..The benefits of human fetal tissue research need greater recognition...
  59. Research ethics--new standards
    George Youngson
    Pediatr Surg Int 20:222-3