stem cell research


Summary: Experimentation on STEM CELLS and on the use of stem cells.

Top Publications

  1. Anisimov S. [Risks of the xenogenic origin in stem cells applications]. Tsitologiia. 2012;54:289-97 pubmed
    ..In the review, key issue related to xenogenic factors in stem cell applications are discussed, as well as the possible means to lower the risks of the xenogenic origin. ..
  2. Pennings G, Segers S, Debrock S, Heindryckx B, Kontozova Deutsch V, Punjabi U, et al. Human embryo research in Belgium: an overview. Fertil Steril. 2017;108:96-107 pubmed publisher
    ..Data collection requires a sufficiently clear definition of "research" and "embryo." These conceptual questions frequently reveal lack of clarity in legislation. ..
  3. Riemens R, Soares E, Esteller M, Delgado Morales R. Stem Cell Technology for (Epi)genetic Brain Disorders. Adv Exp Med Biol. 2017;978:443-475 pubmed publisher
  4. Evans M, Kelley J. US attitudes toward human embryonic stem cell research. Nat Biotechnol. 2011;29:484-8 pubmed publisher
  5. Maartens A. An interview with Jayaraj Rajagopal. Development. 2017;144:3389-3391 pubmed publisher
    ..was awarded the Dr Susan Lim Award for Outstanding Young Investigator at the 2017 International Society for Stem Cell Research (ISSCR) meeting in Boston (MA,USA), where we met him to talk about how a fish tank started a life-long ..
  6. Watanabe N, Santostefano K, Yachnis A, Terada N. A pathologist's perspective on induced pluripotent stem cells. Lab Invest. 2017;97:1126-1132 pubmed publisher
    ..A particular focus will be on introducing the effort to recapitulate disease-related morphological changes through three-dimensional culture of stem cells such as organoid differentiation. ..
  7. Klaus A, Robin C. Embryonic hematopoiesis under microscopic observation. Dev Biol. 2017;428:318-327 pubmed publisher
  8. Garber K. RIKEN suspends first clinical trial involving induced pluripotent stem cells. Nat Biotechnol. 2015;33:890-1 pubmed publisher
  9. Neaves W. The status of the human embryo in various religions. Development. 2017;144:2541-2543 pubmed publisher

More Information


  1. Allum N, Allansdottir A, Gaskell G, Hampel J, Jackson J, Moldovan A, et al. Religion and the public ethics of stem-cell research: Attitudes in Europe, Canada and the United States. PLoS ONE. 2017;12:e0176274 pubmed publisher
    ..We conclude that if anything public opinion or 'public ethics' are likely to play an increasingly important role in framing policy and regulatory regimes for sensitive technologies in the future. ..
  2. Hyun I. Illusory fears must not stifle chimaera research. Nature. 2016;537:281 pubmed publisher
  3. Huang Y, Parolini O, La Rocca G, Deng L. Umbilical cord versus bone marrow-derived mesenchymal stromal cells. Stem Cells Dev. 2012;21:2900-3 pubmed publisher
  4. Yagi M, Yamanaka S, Yamada Y. Epigenetic foundations of pluripotent stem cells that recapitulate in vivo pluripotency. Lab Invest. 2017;97:1133-1141 pubmed publisher
    ..In this review, we describe the developmental potential and epigenetic regulation of pluripotent stem cells in rodents and humans in vitro and discuss unsolved issues in developing strategies to capture in vivo pluripotency in vitro. ..
  5. Twigger A, Scheel C. Advances in stem cells and regenerative medicine: single-cell dynamics, new models and translational perspectives. Development. 2017;144:3007-3011 pubmed publisher
    ..This Meeting Review highlights the novel insights into stem cell regulation, new technologies aiding in discovery and exciting breakthroughs in the field of regenerative medicine that emerged from the meeting. ..
  6. Caulfield T, Sipp D, Murry C, Daley G, Kimmelman J. SCIENTIFIC COMMUNITY. Confronting stem cell hype. Science. 2016;352:776-7 pubmed publisher
  7. Reardon S, Cyranoski D. Japan stem-cell trial stirs envy. Nature. 2014;513:287-8 pubmed publisher
  8. Meskus M, de Miguel Beriain I. Embryo-like features of induced pluripotent stem cells defy legal and ethical boundaries. Croat Med J. 2013;54:589-91 pubmed
  9. Marks P, Witten C, Califf R. Clarifying Stem-Cell Therapy's Benefits and Risks. N Engl J Med. 2017;376:1007-1009 pubmed publisher
  10. Ishii T, Pera R. Creating human germ cells for unmet reproductive needs. Nat Biotechnol. 2016;34:470-3 pubmed publisher
  11. Masaki H, Nakauchi H. Interspecies chimeras for human stem cell research. Development. 2017;144:2544-2547 pubmed publisher
  12. Chen A, Ting S, Seow J, Reuveny S, Oh S. Considerations in designing systems for large scale production of human cardiomyocytes from pluripotent stem cells. Stem Cell Res Ther. 2014;5:12 pubmed publisher
    ..This review discuss key issues such as platform selection, bioprocess parameters, medium development, downstream processing and parameters that meet current good manufacturing practice standards. ..
  13. Higuchi A, Ku N, Tseng Y, Pan C, Li H, Kumar S, et al. Stem cell therapies for myocardial infarction in clinical trials: bioengineering and biomaterial aspects. Lab Invest. 2017;97:1167-1179 pubmed publisher
    ..We explain why the number of clinical trials using hPSCs is so limited compared with clinical trials using human adult and fetal stem cells such as bone marrow-derived stem cells. ..
  14. Oh I, Snyder E. Special feature on stem cells: current research and future prospects. Exp Mol Med. 2013;45:e63 pubmed publisher
  15. Hyun I, Wilkerson A, Johnston J. Embryology policy: Revisit the 14-day rule. Nature. 2016;533:169-71 pubmed publisher
  16. Jurgielewicz P, Harmsen S, Wei E, Bachmann M, Ting R, Aras O. New imaging probes to track cell fate: reporter genes in stem cell research. Cell Mol Life Sci. 2017;74:4455-4469 pubmed publisher
    ..Strengths and limitations of the use of reporter genes in each modality are discussed. ..
  17. Isasi R, Kleiderman E, Knoppers B. GENETIC TECHNOLOGY REGULATION. Editing policy to fit the genome?. Science. 2016;351:337-9 pubmed publisher
  18. den Hertog J, de Laat S. Hubrecht Institute Centennial - From embryos to stem cells. Dev Biol. 2017;428:261-263 pubmed publisher
    ..The past 100 years have been eventful for the Hubrecht Institute with many glorious moments, but also threats to be shut down on several occasions. Here, we will briefly review the rich history of the Hubrecht Institute. ..
  19. Willyard C. The boom in mini stomachs, brains, breasts, kidneys and more. Nature. 2015;523:520-2 pubmed publisher