tungsten compounds

Summary

Summary: Inorganic compounds that contain tungsten as an integral part of the molecule.

Top Publications

  1. Kim H, Kim T, Choi K, Kim I, Kim Y, Hwang S. Self-assembly of nanosized 0D clusters: CdS quantum dot-polyoxotungstate nanohybrids with strongly coupled electronic structures and visible-light-active photofunctions. Chemistry. 2011;17:9626-33 pubmed publisher
    ..e., visible-induced photochromism and photocatalysis) by means of strong electronic coupling...
  2. Collares F, Leitune V, Rostirolla F, Trommer R, Bergmann C, Samuel S. Nanostructured hydroxyapatite as filler for methacrylate-based root canal sealers. Int Endod J. 2012;45:63-7 pubmed publisher
    ..To evaluate the effect of different concentrations of nanostructured hydroxyapatite on the radiopacity, flow and film thickness of an experimental root canal sealer...
  3. Amigó Correig M, Barceló Batllori S, Piquer S, Soty M, Pujadas G, Gasa R, et al. Sodium tungstate regulates food intake and body weight through activation of the hypothalamic leptin pathway. Diabetes Obes Metab. 2011;13:235-42 pubmed publisher
  4. Giron M, Sevillano N, Vargas A, Dominguez J, Guinovart J, Salto R. The glucose-lowering agent sodium tungstate increases the levels and translocation of GLUT4 in L6 myotubes through a mechanism associated with ERK1/2 and MEF2D. Diabetologia. 2008;51:1285-95 pubmed publisher
    ..The aim of this study was to investigate the action of the glucose-lowering compound sodium tungstate on glucose transport in muscle myotubes and to unravel the molecular events underlying the effects observed...
  5. Ballester J, Dominguez J, Muñoz M, Sensat M, Rigau T, Guinovart J, et al. Tungstate treatment improves Leydig cell function in streptozotocin-diabetic rats. J Androl. 2005;26:706-15 pubmed
  6. Giron M, Caballero J, Vargas A, Suarez M, Guinovart J, Salto R. Modulation of glucose transporters in rat diaphragm by sodium tungstate. FEBS Lett. 2003;542:84-8 pubmed
    ..We conclude that the normoglycemic effect of tungstate may be partly due to a normalization of the levels and subcellular localization of GLUT4, which should result in an increase in muscle glucose uptake...
  7. Liu H, Green B, McClenaghan N, McCluskey J, Flatt P. Long-term beneficial effects of vanadate, tungstate, and molybdate on insulin secretion and function of cultured beta cells. Pancreas. 2004;28:364-8 pubmed
    ..These observations suggest significant effects of ultratrace elements on pancreatic beta cells that may contribute to their antihyperglycemic action...
  8. Stevanato R, Fabris S, Momo F. New enzymatic method for the determination of total phenolic content in tea and wine. J Agric Food Chem. 2004;52:6287-93 pubmed
    ..The differences of the total phenols content found by applying the three methods are discussed in terms of the different specificities of the analytical basis...
  9. Andreesen J, Makdessi K. Tungsten, the surprisingly positively acting heavy metal element for prokaryotes. Ann N Y Acad Sci. 2008;1125:215-29 pubmed
    ..By that process, tungsten finally becomes selectively incorporated into the few enzymes noted above...

More Information

Publications62

  1. Barceló Batllori S, Kalko S, Esteban Y, Moreno S, Carmona M, Gomis R. Integration of DIGE and bioinformatics analyses reveals a role of the antiobesity agent tungstate in redox and energy homeostasis pathways in brown adipose tissue. Mol Cell Proteomics. 2008;7:378-93 pubmed
  2. Canals I, Carmona M, Amigó M, Barbera A, Bortolozzi A, Artigas F, et al. A functional leptin system is essential for sodium tungstate antiobesity action. Endocrinology. 2009;150:642-50 pubmed publisher
    ..In summary, the results indicate that the effectiveness of tungstate in reducing body weight gain is completely dependent on a functional leptin system...
  3. Kühnel D, Busch W, Meissner T, Springer A, Potthoff A, Richter V, et al. Agglomeration of tungsten carbide nanoparticles in exposure medium does not prevent uptake and toxicity toward a rainbow trout gill cell line. Aquat Toxicol. 2009;93:91-9 pubmed publisher
    ..Taken together, our findings indicate that minimal exposure media can lead to rapid agglomeration of nanoparticles but that agglomeration does not prevent uptake into cells and the expression of toxicity...
  4. Stankiewicz P, Gresser M. Inhibition of phosphatase and sulfatase by transition-state analogues. Biochemistry. 1988;27:206-12 pubmed
    ..The relevance of these observations to the effects of transition metal oxyanions on protein phosphatases in vivo is discussed...
  5. Huang D, Ou B, Prior R. The chemistry behind antioxidant capacity assays. J Agric Food Chem. 2005;53:1841-56 pubmed
    ..To comprehensively study different aspects of antioxidants, validated and specific assays are needed in addition to these two commonly accepted assays...
  6. Lombaert N, De Boeck M, Decordier I, Cundari E, Lison D, Kirsch Volders M. Evaluation of the apoptogenic potential of hard metal dust (WC-Co), tungsten carbide and metallic cobalt. Toxicol Lett. 2004;154:23-34 pubmed
    ..The apoptogenic properties of these metals may be important in the mechanism of lung pathologies induced by the cobalt-containing particles...
  7. Barbera A, Gomis R, Prats N, Rodriguez Gil J, Domingo M, Gomis R, et al. Tungstate is an effective antidiabetic agent in streptozotocin-induced diabetic rats: a long-term study. Diabetologia. 2001;44:507-13 pubmed
    ..In this study, we examined the effectiveness of long-term tungstate treatment of streptozotocin-induced-diabetic rats...
  8. Imperial J, Hadi M, Amy N. Molybdate binding by ModA, the periplasmic component of the Escherichia coli mod molybdate transport system. Biochim Biophys Acta. 1998;1370:337-46 pubmed
    ..The affinity of ModA for molybdate was also determined in vivo and found to be similar to that determined in vitro...
  9. Smart J, Cliff M, Kelly D. A role for tungsten in the biology of Campylobacter jejuni: tungstate stimulates formate dehydrogenase activity and is transported via an ultra-high affinity ABC system distinct from the molybdate transporter. Mol Microbiol. 2009;74:742-57 pubmed publisher
    ..Furthermore, possession of two MoeA paralogues may explain the formation of both molybdopterin and tungstopterin in this bacterium...
  10. Kalinich J, Emond C, Dalton T, Mog S, Coleman G, Kordell J, et al. Embedded weapons-grade tungsten alloy shrapnel rapidly induces metastatic high-grade rhabdomyosarcomas in F344 rats. Environ Health Perspect. 2005;113:729-34 pubmed
    ..These results point out the need for further studies investigating the health effects of tungsten and tungsten-based alloys...
  11. Peuster M, Fink C, Wohlsein P, Bruegmann M, Günther A, Kaese V, et al. Degradation of tungsten coils implanted into the subclavian artery of New Zealand white rabbits is not associated with local or systemic toxicity. Biomaterials. 2003;24:393-9 pubmed
    ..To assess whether corrosion of tungsten coils is related to residual shunting and to evaluate whether elevated tungsten serum levels are associated with local or systemic toxicity...
  12. Silvestre R, Egido E, Hernandez R, Marco J. Tungstate stimulates insulin release and inhibits somatostatin output in the perfused rat pancreas. Eur J Pharmacol. 2005;519:127-34 pubmed
  13. Imeh U, Khokhar S. Distribution of conjugated and free phenols in fruits: antioxidant activity and cultivar variations. J Agric Food Chem. 2002;50:6301-6 pubmed
    ..The calculated dietary intake of total, free, and conjugated phenols from average per capita consumption of apples and pears in different regions of the U.K. varied between 104-126, 53-64, and 51-62 mg of CtE/day, respectively...
  14. Ozer R, Ferry J. Investigation of the photocatalytic activity of TiO2--polyoxometalate systems. Environ Sci Technol. 2001;35:3242-6 pubmed
    ..0818, 0.152, 0.421, and 0.638 min(-1), respectively. An analysis of deltaG for electron transfer from the conduction band of TiO2 to POMs in this study shows that the electron transfer takes place even when it is endothermic...
  15. Munoz M, Barbera A, Dominguez J, Fernandez Alvarez J, Gomis R, Guinovart J. Effects of tungstate, a new potential oral antidiabetic agent, in Zucker diabetic fatty rats. Diabetes. 2001;50:131-8 pubmed
    ..These data suggest that tungstate administration to ZDF rats causes a considerable reduction of glycemia, mainly through a partial restoration of hepatic glucose metabolism and a decrease in lipotoxicity...
  16. Lombaert N, Lison D, Van Hummelen P, Kirsch Volders M. In vitro expression of hard metal dust (WC-Co)--responsive genes in human peripheral blood mononucleated cells. Toxicol Appl Pharmacol. 2008;227:299-312 pubmed
    ..Overall, this study provides the first analysis of gene expression induced by the WC-Co mixture showing a large profile of gene modulation and giving a preliminary indication for a hypoxia mimicking environment induced by WC-Co exposure...
  17. Barbera A, Rodriguez Gil J, Guinovart J. Insulin-like actions of tungstate in diabetic rats. Normalization of hepatic glucose metabolism. J Biol Chem. 1994;269:20047-53 pubmed
    ..Tungstate administration in healthy animals also affected all these parameters, although to a much lesser extent. All these effects were similar to those previously reported for vanadate, suggesting a common mechanism of action in vivo...
  18. Bastian S, Busch W, Kühnel D, Springer A, Meissner T, Holke R, et al. Toxicity of tungsten carbide and cobalt-doped tungsten carbide nanoparticles in mammalian cells in vitro. Environ Health Perspect. 2009;117:530-6 pubmed publisher
    ..To develop nanoparticles for broad applications, potential risks to human health and the environment should be evaluated and taken into consideration...
  19. Miró Queralt M, Guinovart J, Planas J. Sodium tungstate decreases sucrase and Na+/D-glucose cotransporter in the jejunum of diabetic rats. Am J Physiol Gastrointest Liver Physiol. 2008;295:G479-84 pubmed publisher
    ..We conclude that the antidiabetic effect of tungstate is partly due to normalization of the activity of sucrase and SGLT1 in the brush-border membrane of enterocytes...
  20. Gómez Ramos A, Dominguez J, Zafra D, Corominola H, Gomis R, Guinovart J, et al. Sodium tungstate decreases the phosphorylation of tau through GSK3 inactivation. J Neurosci Res. 2006;83:264-73 pubmed
    ..The phosphorylation at these sites is involved in reduction of the interaction of tau with microtubules that occurs in Alzheimer's disease...
  21. Barceló Batllori S, Corominola H, Claret M, Canals I, Guinovart J, Gomis R. Target identification of the novel antiobesity agent tungstate in adipose tissue from obese rats. Proteomics. 2005;5:4927-35 pubmed
    ..These findings open new avenues for the study of the aetiology of obesity and its treatment...
  22. Claret M, Corominola H, Canals I, Saura J, Barceló Batllori S, Guinovart J, et al. Tungstate decreases weight gain and adiposity in obese rats through increased thermogenesis and lipid oxidation. Endocrinology. 2005;146:4362-9 pubmed
    ..Furthermore, treatment increased the number of small adipocytes with a concomitant induction of apoptosis. Our results indicate that tungstate treatment may provide the basis for a promising novel therapy for obesity...
  23. Fernandez Alvarez J, Barbera A, Nadal B, Barceló Batllori S, Piquer S, Claret M, et al. Stable and functional regeneration of pancreatic beta-cell population in nSTZ-rats treated with tungstate. Diabetologia. 2004;47:470-477 pubmed publisher
    ..Sodium tungstate has recently emerged as an effective oral treatment for diabetes. We examined the effects of tungstate administration in the beta-cell mass of the pancreas as well as its therapeutic potential...
  24. Piquer S, Barceló Batllori S, Julià M, Marzo N, Nadal B, Guinovart J, et al. Phosphorylation events implicating p38 and PI3K mediate tungstate-effects in MIN6 beta cells. Biochem Biophys Res Commun. 2007;358:385-91 pubmed
    ..These results show a direct involvement of p38 and PI3K phosphorylation in the mechanism of action of tungstate in the beta cell...
  25. van Goethem F, Lison D, Kirsch Volders M. Comparative evaluation of the in vitro micronucleus test and the alkaline single cell gel electrophoresis assay for the detection of DNA damaging agents: genotoxic effects of cobalt powder, tungsten carbide and cobalt-tungsten carbide. Mutat Res. 1997;392:31-43 pubmed
    ..Combination of the comet assay and the in vitro MN test might therefore be recommended for genotoxins to understand the mechanisms underlying mutagenicity and to assess the lowest efficient dose...
  26. Domínguez J, Muñoz M, Zafra D, Sanchez Perez I, Baqué S, Caron M, et al. The antidiabetic agent sodium tungstate activates glycogen synthesis through an insulin receptor-independent pathway. J Biol Chem. 2003;278:42785-94 pubmed
    ..These results show a direct involvement of ERK1/2 in the mechanism of action of tungstate at the hepatic level...
  27. Hoet P, Roesems G, Demedts M, Nemery B. Activation of the hexose monophosphate shunt in rat type II pneumocytes as an early marker of oxidative stress caused by cobalt particles. Arch Toxicol. 2002;76:1-7 pubmed
    ..However, we were not able to show a simple relationship between the stimulation of the HMS and the subsequent cell damage...
  28. Xu M, Li H, Zhang L, Wang Y, Yuan Y, Zhang J, et al. Charge and pressure-tuned surface patterning of surfactant-encapsulated polyoxometalate complexes at the air-water interface. Langmuir. 2012;28:14624-32 pubmed publisher
    ..This finding can direct a new strategy for the fabrication of POM-hybrid films with controllable patterns, which should be instructive for designing POM-based thin film devices...
  29. Appia Ayme C, Patrick E, Sullivan M, Alston M, Field S, Abuoun M, et al. Novel inducers of the envelope stress response BaeSR in Salmonella Typhimurium: BaeR is critically required for tungstate waste disposal. PLoS ONE. 2011;6:e23713 pubmed publisher
    ..BaeR is therefore either required for survival in larger mammals such as pigs or calves, an avian host such as chickens, or survival out with the host altogether where Salmonella and related enterics must survive in soil and water...
  30. Murakami M, Hong D, Suenobu T, Yamaguchi S, Ogura T, Fukuzumi S. Catalytic mechanism of water oxidation with single-site ruthenium-heteropolytungstate complexes. J Am Chem Soc. 2011;133:11605-13 pubmed publisher
    ..Complex 2 exhibited a higher catalytic reactivity for the water oxidation with CAN than did complex 1...
  31. Song X, Zhang Z, Xu Y, Wang J, Zhou H, Song Y. Assembling 1D magnetic chain based on octacyanotungstate(V) and [Cu2L2Ln] sub-building units (Ln = Eu, Gd, Tb and Dy). Dalton Trans. 2013;42:9505-12 pubmed publisher
    ..Magnetic investigation indicates that ferromagnetic interaction occurred between all paramagnetic ions and the slow magnetic relaxation properties were observed in complexes 3 and 4...
  32. Xiao Y, Han Y, Xia N, Hu M, Zheng P, Wang W. Macromolecule-to-amphiphile conversion process of a polyoxometalate-polymer hybrid and assembled hybrid vesicles. Chemistry. 2012;18:11325-33 pubmed publisher
    ..The success in the preparation of the POM-containing hybrid vesicles provides us with an opportunity of preparing POM-functionalized vesicles...
  33. Zhang Z, Yao S, Li Y, Han X, Su Z, Wang Z, et al. Inorganic crown ethers: sulfate-based Preyssler polyoxometalates. Chemistry. 2012;18:9184-8 pubmed publisher
    ..The as-prepared polyoxoanion exhibits an interesting ion-selective encapsulation of K(+) and Na(+) (see figure)...
  34. Xuan W, Xu S, Li M, Han B, Zhang B, Zhang J, et al. Nitric oxide is involved in hemin-induced cucumber adventitious rooting process. J Plant Physiol. 2012;169:1032-9 pubmed publisher
    ..Together, our results indicated that at least in our experimental conditions, NO might operate downstream of hemin promoting adventitious root formation probably in a cGMP-dependent manner...
  35. Rakshit S, Sallman B, Davantés A, Lefevre G. Tungstate (VI) sorption on hematite: An in situ ATR-FTIR probe on the mechanism. Chemosphere. 2017;168:685-691 pubmed publisher
    ..In addition, initial W (VI) concentration affected the sorption mechanisms of W (VI) on hematite. Our study will aid the molecular level understanding of W (VI) retention on iron oxide surfaces. ..
  36. Zhao J, Bowman L, Magaye R, Leonard S, Castranova V, Ding M. Apoptosis induced by tungsten carbide-cobalt nanoparticles in JB6 cells involves ROS generation through both extrinsic and intrinsic apoptosis pathways. Int J Oncol. 2013;42:1349-59 pubmed publisher
    ..Apoptosis induced by WC-Co nanoparticles and fine particles involves both extrinsic and intrinsic apoptosis pathways...
  37. Hirano T, Uehara K, Kamata K, Mizuno N. Palladium(II) containing ?-Keggin silicodecatungstate that efficiently catalyzes hydration of nitriles. J Am Chem Soc. 2012;134:6425-33 pubmed publisher
  38. Fraqueza G, Ohlin C, Casey W, Aureliano M. Sarcoplasmic reticulum calcium ATPase interactions with decaniobate, decavanadate, vanadate, tungstate and molybdate. J Inorg Biochem. 2012;107:82-9 pubmed publisher
  39. Sharon E, Shapira L, Wilensky A, Abu Hatoum R, Smidt A. Efficiency and thermal changes during implantoplasty in relation to bur type. Clin Implant Dent Relat Res. 2013;15:292-6 pubmed publisher
    ..The efficacy of the dental bur used can reduce the time needed for the procedure and, as a consequence, minimize the risk of overheating that can negatively affect the remaining bone surrounding the implant...
  40. Aguilar Barajas E, Díaz Pérez C, Ramírez Díaz M, Riveros Rosas H, Cervantes C. Bacterial transport of sulfate, molybdate, and related oxyanions. Biometals. 2011;24:687-707 pubmed publisher
    ..CysPTWA, ModABC, TupABC, and WtpABC are homologous ATP-binding cassette (ABC)-type transporters with similar organization and properties. Uptake of selenate and chromate oxyanions occurs mainly through sulfate permeases...
  41. Ryf S, Flury S, Palaniappan S, Lussi A, Van Meerbeek B, Zimmerli B. Enamel loss and adhesive remnants following bracket removal and various clean-up procedures in vitro. Eur J Orthod. 2012;34:25-32 pubmed publisher
    ..32 mm(3)). There were no statistically significant differences in volumetric changes after polishing (P?=?0.054) between the different clean-up methods. However, sufficient clean-up without enamel loss was difficult to achieve...
  42. Ravelli D, Dondi D, Fagnoni M, Albini A, Bagno A. Predicting the UV spectrum of polyoxometalates by TD-DFT. J Comput Chem. 2011;32:2983-7 pubmed publisher
    ..The approach was extended to [W(10)O(32)](4-) and [PW(12)O(40)](3-), suggesting that it can be applied to the polyoxometalates family...
  43. Schäffer C, Todea A, Bögge H, Petina O, Rehder D, Haupt E, et al. Hydrophobic interactions and clustering in a porous capsule: option to remove hydrophobic materials from water. Chemistry. 2011;17:9634-9 pubmed publisher
    ..Future detailed studies will focus on interactions of a variety of hydrophobic species with different deliberately constructed hydrophobic capsule interiors...
  44. Lydon C, Sabi M, Symes M, Long D, Murrie M, Yoshii S, et al. Directed assembly of nanoscale Co(II)-substituted {Co9[P2W15]3} and {Co14[P2W15]4} polyoxometalates. Chem Commun (Camb). 2012;48:9819-21 pubmed publisher
    ..Compound 1 displays a structure previously predicted but never before realised, whilst compound 2 is the first Co-containing Dawson-based single-molecule magnet and has a unique cruciform structure...
  45. Maharaj D, Bhushan B, Iijima S. Effect of carbon nanohorns on nanofriction and wear reduction in dry and liquid environments. J Colloid Interface Sci. 2013;400:147-60 pubmed publisher
    ..Results indicate CNH nanoparticles contribute to friction and wear reduction due to the reduced contact area and low meniscus force contribution...
  46. Peerzada F, Yiu C, Hiraishi N, Tay F, King N. Effect of surface preparation on bond strength of resin luting cements to dentin. Oper Dent. 2010;35:624-33 pubmed publisher
    ..For Panavia F2.0, higher bond strengths were achieved on the dentin surface prepared with a tungsten carbide bur. Proper bur selection is essential to optimizing the dentin adhesion of self-etch resin luting cements...
  47. Sari E, Ayyildiz N. Biological activities and some physicochemical properties of sunflower honeys collected from the Thrace region of Turkey. Pak J Biol Sci. 2012;15:1102-10 pubmed
    ..This is the first report of the total phenolic content, antioxidant and antiradical activities of sunflower honeys collected from the Thrace region of Turkey...
  48. Salto R, Vílchez J, Cabrera E, Guinovart J, Girón M. Activation of ERK by sodium tungstate induces protein synthesis and prevents protein degradation in rat L6 myotubes. FEBS Lett. 2014;588:2246-54 pubmed publisher
    ..On the basis of our results, we propose that tungstate be considered an alternative to IGF-I and its analogs in the prevention of skeletal muscle atrophy. ..
  49. Yang M, Kim D, Lee T, Lee S, Lee K, Choi B. Polyoxometalate-grafted graphene nanohybrid for electrochemical detection of hydrogen peroxide and glucose. J Colloid Interface Sci. 2016;468:51-56 pubmed publisher
  50. Natali M, Orlandi M, Berardi S, Campagna S, Bonchio M, Sartorel A, et al. Photoinduced water oxidation by a tetraruthenium polyoxometalate catalyst: ion-pairing and primary processes with Ru(bpy)3(2+) photosensitizer. Inorg Chem. 2012;51:7324-31 pubmed publisher
    ..45 turnovers in Ru(bpy)(3)(3+) reduction. With the assumption that one molecule of oxygen released after four hole-scavenging events, this translates into a very high average turnover frequency (280 s(-1)) for oxygen production...
  51. Uehara K, Fukaya K, Mizuno N. Reactive N-protonated isocyanate species stabilized by bis(?-hydroxo)divanadium(IV)-substituted polyoxometalate. Angew Chem Int Ed Engl. 2012;51:7715-8 pubmed publisher
    ..Its reaction with phenyl isocyanate gave (TBA)(4)[?-SiV(IV)(2)W(10)O(38)(?-OH)(2)(PhNHCO)(2)], which contains two N-protonated phenyl isocyanate species and catalyzes the cyclotrimerization of phenyl isocyanate...
  52. Oliveira J, Rebuffat S, Gasa R, Burks D, García A, Kalko S, et al. Tungstate promotes ?-cell survival in Irs2-/- mice. Am J Physiol Endocrinol Metab. 2014;306:E36-47 pubmed publisher
    ..Our results support the finding that ?-cell death can be arrested in the absence of IRS2 and that therapies aimed at reversing ?-cell mass decline are potential strategies to prevent the progression to T2D...
  53. Meissner T, Kühnel D, Busch W, Oswald S, Richter V, Michaelis A, et al. Physical-chemical characterization of tungsten carbide nanoparticles as a basis for toxicological investigations. Nanotoxicology. 2010;4:196-206 pubmed publisher
    ..In the presence of bovine serum albumin (BSA) or serum, the agglomeration process is decelerated or, at the appropriate protein amount, prevented...