diazinon

Summary

Summary: A cholinesterase inhibitor that is used as an organothiophosphorus insecticide.

Top Publications

  1. Hariri A, Moallem S, Mahmoudi M, Memar B, Hosseinzadeh H. Sub-acute effects of diazinon on biochemical indices and specific biomarkers in rats: protective effects of crocin and safranal. Food Chem Toxicol. 2010;48:2803-8 pubmed publisher
    In this study, the effects of crocin and safranal were studied against sub-acute toxicity of diazinon (DZN) on specific biomarkers, biochemical indices and enzymes levels in rats. Vitamin E (200 IU/kg), safranal at doses 0.025, 0.05 and 0...
  2. Aluigi M, Angelini C, Corte G, Falugi C. The sea urchin, Paracentrotus lividus, embryo as a "bioethical" model for neurodevelopmental toxicity testing: effects of diazinon on the intracellular distribution of OTX2-like proteins. Cell Biol Toxicol. 2008;24:587-601 pubmed publisher
    ..sea urchin early developmental stages were used as a model to test the effects of the organophosphate pesticide (diazinon) on the regulation of gene expression by immunohistochemical localization of the human regulatory protein against ..
  3. Barrett K, Jaward F. A review of endosulfan, dichlorvos, diazinon, and diuron--pesticides used in Jamaica. Int J Environ Health Res. 2012;22:481-99 pubmed publisher
    ..This review discusses four pesticides extensively applied in agricultural practices in Jamaica - endosulfan, diazinon, diuron, and dichlorvos...
  4. Girón Pérez M, Zaitseva G, Casas Solis J, Santerre A. Effects of diazinon and diazoxon on the lymphoproliferation rate of splenocytes from Nile tilapia (Oreochromis niloticus): the immunosuppresive effect could involve an increase in acetylcholine levels. Fish Shellfish Immunol. 2008;25:517-21 pubmed publisher
    ..rate of spleen cells from Nile tilapia (Oreochromis niloticus) exposed to the organophosphorus pesticide diazinon, to its metabolite diazoxon and to the neurotransmitter acetylcholine, was evaluated in order to explore the ..
  5. Viant M, Pincetich C, Tjeerdema R. Metabolic effects of dinoseb, diazinon and esfenvalerate in eyed eggs and alevins of Chinook salmon (Oncorhynchus tshawytscha) determined by 1H NMR metabolomics. Aquat Toxicol. 2006;77:359-71 pubmed
    ..Three pesticides currently used in the Sacramento Valley-- dinoseb, diazinon, and esfenvalerate-- were chosen to model the exposure of salmon embryos to storm-water discharges...
  6. Shemer H, Linden K. Degradation and by-product formation of diazinon in water during UV and UV/H(2)O(2) treatment. J Hazard Mater. 2006;136:553-9 pubmed
    ..products resulting from the application of UV and UV/H(2)O(2) to the US EPA Contaminant Candidate List pesticide diazinon were studied. Batch experiments were conducted with both monochromatic (low pressure [LP] UV 253...
  7. Poet T, Wu H, Kousba A, Timchalk C. In vitro rat hepatic and intestinal metabolism of the organophosphate pesticides chlorpyrifos and diazinon. Toxicol Sci. 2003;72:193-200 pubmed
    Chlorpyrifos (CPF) and diazinon (DZN) are thionophosphorus organophosphate (OP) insecticides; their toxicity is mediated through CYP metabolism to CPF-oxon and DZN-oxon, respectively...
  8. Adigun A, Wrench N, Seidler F, Slotkin T. Neonatal organophosphorus pesticide exposure alters the developmental trajectory of cell-signaling cascades controlling metabolism: differential effects of diazinon and parathion. Environ Health Perspect. 2010;118:210-5 pubmed publisher
    ..We administered diazinon (DZN) or parathion (PRT) to rats on postnatal days 14 at doses straddling the threshold for systemic signs of ..
  9. Laetz C, Baldwin D, Hebert V, Stark J, Scholz N. Interactive neurobehavioral toxicity of diazinon, malathion, and ethoprop to juvenile coho salmon. Environ Sci Technol. 2013;47:2925-31 pubmed publisher
    ..near or below 1 part per billion), juvenile coho (Oncorhynchus kisutch) were exposed to a range of mixtures of diazinon-malathion and ethoprop-malathion below a cumulative 0...

More Information

Publications62

  1. Sarabia L, Maurer I, Bustos Obregon E. Melatonin prevents damage elicited by the organophosphorous pesticide diazinon on the mouse testis. Ecotoxicol Environ Saf. 2009;72:938-42 pubmed publisher
    Organophosphates like O,O-diethyl O-2-isopropyl-6-methyl pyrimidinyl-4-g-1-phosphorothioate (diazinon) are pesticides used worldwide, which can affect both animals and man even after a single exposure...
  2. Brasel J, Collier A, Pritsos C. Differential toxic effects of Carbofuran and Diazinon on time of flight in pigeons (Columba livia): potential for pesticide effects on migration. Toxicol Appl Pharmacol. 2007;219:241-6 pubmed
    ..Carbofuran, a carbamate, and diazinon, an organophosphate, are among the most commonly implicated cholinesterase inhibitors in episodes of accidental ..
  3. Banks K, Hunter D, Wachal D. Diazinon in surface waters before and after a federally-mandated ban. Sci Total Environ. 2005;350:86-93 pubmed
    ..from rural and urban streams in the City of Denton, Texas, USA were analyzed for the organophosphorus pesticide diazinon during the years preceding and following a United States Environmental Protection Agency ban on many diazinon ..
  4. Morgan M, Sheldon L, Jones P, Croghan C, Chuang J, Wilson N. The reliability of using urinary biomarkers to estimate children's exposures to chlorpyrifos and diazinon. J Expo Sci Environ Epidemiol. 2011;21:280-90 pubmed publisher
    A few studies have reported concurrent levels of chlorpyrifos (CPF) and diazinon (DZN) and their environmentally occurring metabolites, 3,5,6-trichloro-2-pyridinol (TCP) and 2-isopropyl-6-methyl-4-pyrimidinol (IMP), in food and in ..
  5. Hariri A, Moallem S, Mahmoudi M, Hosseinzadeh H. The effect of crocin and safranal, constituents of saffron, against subacute effect of diazinon on hematological and genotoxicity indices in rats. Phytomedicine. 2011;18:499-504 pubmed publisher
    In this study, the effect of crocin and safranal was studied against subacute toxicity of diazinon (DZN) on hematological and genotoxicity indices in rats...
  6. Ellison C, Tian Y, Knaak J, Kostyniak P, Olson J. Human hepatic cytochrome P450-specific metabolism of the organophosphorus pesticides methyl parathion and diazinon. Drug Metab Dispos. 2012;40:1-5 pubmed publisher
    ..investigated the rate of desulfuration (activation) and dearylation (detoxification) of methyl parathion and diazinon in human liver microsomes...
  7. Messarah M, Amamra W, Boumendjel A, Barkat L, Bouasla I, Abdennour C, et al. Ameliorating effects of curcumin and vitamin E on diazinon-induced oxidative damage in rat liver and erythrocytes. Toxicol Ind Health. 2013;29:77-88 pubmed publisher
    The aim of this study was to evaluate the protective effects of vitamin E and/or curcumin against diazinon (DZN) (an organophosphorus insecticide)-induced toxicity of blood, liver and erythrocyte markers of male Wistar rats...
  8. Slotkin T, Ryde I, Levin E, Seidler F. Developmental neurotoxicity of low dose diazinon exposure of neonatal rats: effects on serotonin systems in adolescence and adulthood. Brain Res Bull. 2008;75:640-7 pubmed publisher
    ..We exposed neonatal rats to daily doses of diazinon on postnatal days 1-4, using doses (0...
  9. Moschandreas D, Karuchit S, Kim Y, Ari H, Lebowitz M, O Rourke M, et al. On predicting multi-route and multimedia residential exposure to chlorpyrifos and diazinon. J Expo Anal Environ Epidemiol. 2001;11:56-65 pubmed
    This paper formulates regression models and examines their ability to associate exposures to chlorpyrifos and diazinon in residences with information obtained from questionnaires and environmental sampling of the National Human Exposure ..
  10. Roegge C, Timofeeva O, Seidler F, Slotkin T, Levin E. Developmental diazinon neurotoxicity in rats: later effects on emotional response. Brain Res Bull. 2008;75:166-72 pubmed
    Developmental exposure to the organophosphorus pesticides chlorpyrifos and diazinon (DZN) alters serotonergic synaptic function at doses below the threshold for cholinesterase inhibition, however there are some indications that the two ..
  11. Ashauer R, Hintermeister A, Caravatti I, Kretschmann A, Escher B. Toxicokinetic and toxicodynamic modeling explains carry-over toxicity from exposure to diazinon by slow organism recovery. Environ Sci Technol. 2010;44:3963-71 pubmed publisher
    ..Carry-over toxicity was observed after exposure of the freshwater amphipod Gammarus pulex to repeated pulses of diazinon with varying intervals. Uptake, biotransformation and depuration kinetics were determined...
  12. Aluigi M, Guida C, Falugi C. Apoptosis as a specific biomarker of diazinon toxicity in NTera2-D1 cells. Chem Biol Interact. 2010;187:299-303 pubmed publisher
    ..NT2 cells exposed to the OP insecticide diazinon at concentrations ranging between 10(-4) and 10(-5)M showed a time-dependent enhancement of cell death...
  13. Holmes R, de Vlaming V. Monitoring of diazinon concentrations and loadings, and identification of geographic origins consequent to stormwater runoff from orchards in the Sacramento River watershed, U.S.A. Environ Monit Assess. 2003;87:57-79 pubmed
    b>Diazinon contamination of California's rivers has resulted in placing several rivers on the federal Clean Water Act 303d list of impaired waterways. Impaired water body listing requires the development of Total Maximum Daily Loads (TMDL)...
  14. Axelrad J, Howard C, McLean W. The effects of acute pesticide exposure on neuroblastoma cells chronically exposed to diazinon. Toxicology. 2003;185:67-78 pubmed
    ..NB2a neuroblastoma cells were grown in the presence of 25 microM diazinon for 8 weeks...
  15. Sarabia L, Maurer I, Bustos Obregon E. Melatonin prevents damage elicited by the organophosphorous pesticide diazinon on mouse sperm DNA. Ecotoxicol Environ Saf. 2009;72:663-8 pubmed publisher
    Toxic effects of pesticides are commonly associated with DNA damage. To evaluate the effect of the organophosphate diazinon on sperm DNA and to test whether melatonin could prevent this damage, male mice were intraperitoneally treated ..
  16. Ueyama J, Wang D, Kondo T, Saito I, Takagi K, Takagi K, et al. Toxicity of diazinon and its metabolites increases in diabetic rats. Toxicol Lett. 2007;170:229-37 pubmed
    The effect of diazinon (DZN) on the activities of cholinesterase (ChE) in plasma and acetylcholinesterase (AChE) in erythrocyte and brain was investigated in normal and streptozotocin-induced diabetic rats...
  17. Ducolomb Y, Casas E, Valdez A, Gonzalez G, Altamirano Lozano M, Betancourt M. In vitro effect of malathion and diazinon on oocytes fertilization and embryo development in porcine. Cell Biol Toxicol. 2009;25:623-33 pubmed publisher
    b>Diazinon and malathion are commonly used organophosphate insecticides in agriculture, industry, and in veterinary medicine as an ectoparasiticide...
  18. Miller R, Li A, Tijerina M, Davey R, George J. Differential response to diazinon and coumaphos in a strain of Boophilus microplus (Acari: Ixodidae) collected in Mexico. J Med Entomol. 2008;45:905-11 pubmed
    Boophilus microplus, collected from Nuevo Leon, Mexico, were found to be highly resistant to diazinon but not highly resistant to coumaphos, suggesting that different mechanisms of resistance were present in these ticks than other Mexican ..
  19. Weick J, Thorn R. Effects of acute sublethal exposure to coumaphos or diazinon on acquisition and discrimination of odor stimuli in the honey bee (Hymenoptera: Apidae). J Econ Entomol. 2002;95:227-36 pubmed
    Two organophosphate compounds, coumaphos and diazinon, were examined for effects of sublethal exposure on odor learning and generalization in honey bees, Apis mellifera L...
  20. Slotkin T, Seidler F. Oxidative and excitatory mechanisms of developmental neurotoxicity: transcriptional profiles for chlorpyrifos, diazinon, dieldrin, and divalent nickel in PC12 cells. Environ Health Perspect. 2009;117:587-96 pubmed publisher
    ..We compared the effects of organophosphates (chlorpyrifos and diazinon), an organo-chlorine (dieldrin), and a metal [divalent nickel (Ni2+)] to determine how these mechanisms ..
  21. Timofeeva O, Roegge C, Seidler F, Slotkin T, Levin E. Persistent cognitive alterations in rats after early postnatal exposure to low doses of the organophosphate pesticide, diazinon. Neurotoxicol Teratol. 2008;30:38-45 pubmed
    ..We have found persisting effects of developmental chlorpyrifos (CPF) and diazinon (DZN) on cholinergic and serotonergic neurotransmitter systems and gene expression as well as behavioral function...
  22. Tisch M, Schmezer P, Faulde M, Groh A, Maier H. Genotoxicity studies on permethrin, DEET and diazinon in primary human nasal mucosal cells. Eur Arch Otorhinolaryngol. 2002;259:150-3 pubmed
    Possible genotoxic effects exerted by three widely used pesticides, permethrin, N,N-diethyl-m-toluamide (DEET) and diazinon, in primary human nasal mucosal cells were investigated...
  23. Altuntas I, Kilinc I, Orhan H, Demirel R, Koylu H, Delibas N. The effects of diazinon on lipid peroxidation and antioxidant enzymes in erythrocytes in vitro. Hum Exp Toxicol. 2004;23:9-13 pubmed
    b>Diazinon is one of the most widely used organophosphate insecticides (OPI) in agriculture and public health programs...
  24. Garfitt S, Jones K, Mason H, Cocker J. Exposure to the organophosphate diazinon: data from a human volunteer study with oral and dermal doses. Toxicol Lett. 2002;134:105-13 pubmed
    Biological monitoring of occupational exposure to diazinon is possible by the determination of blood cholinesterase activity and by the measurement of metabolites in urine...
  25. Lu C, Irish R, Fenske R. Biological monitoring of diazinon exposure using saliva in an animal model. J Toxicol Environ Health A. 2003;66:2315-25 pubmed
    ..In this study, the feasibility of using saliva as a tool for measuring diazinon exposure was determined in an animal model...
  26. Li A, Davey R, Miller R, George J. Resistance to coumaphos and diazinon in Boophilus microplus (Acari: Ixodidae) and evidence for the involvement of an oxidative detoxification mechanism. J Med Entomol. 2003;40:482-90 pubmed
    The levels of resistance to two organophosphate acaricides, coumaphos and diazinon, in several Mexican strains of Boophilus microplus (Canestrini) were evaluated using the FAO larval packet test...
  27. Neishabouri E, Hassan Z, Azizi E, Ostad S. Evaluation of immunotoxicity induced by diazinon in C57bl/6 mice. Toxicology. 2004;196:173-9 pubmed
    b>Diazinon (DZN), an organophosphate insecticide, has been used in agriculture for several years. It is possible the residue of this compound to be recycled in the biological system. There is no report on DZN immunotoxicity potential...
  28. Fenlon K, Andreou K, Jones K, Semple K. The formation of bound residues of diazinon in four UK soils: implications for risk assessment. Environ Pollut. 2011;159:776-81 pubmed publisher
    The behaviour of diazinon in the soil determines the likelihood of further pollution incidents, particularly leaching to water...
  29. Shokrzadeh M, Ahangar N, Abdollahi M, Shadboorestan A, Omidi M, Payam S. Potential chemoprotective effects of selenium on diazinon-induced DNA damage in rat peripheral blood lymphocyte. Hum Exp Toxicol. 2013;32:759-65 pubmed publisher
    ..purpose of this study was to investigate the protective effects of selenium (Se) against genotoxicity induced by diazinon (DZN) in rat peripheral blood lymphocytes by micronucleus (MN) test...
  30. Giordano G, Afsharinejad Z, Guizzetti M, Vitalone A, Kavanagh T, Costa L. Organophosphorus insecticides chlorpyrifos and diazinon and oxidative stress in neuronal cells in a genetic model of glutathione deficiency. Toxicol Appl Pharmacol. 2007;219:181-9 pubmed
    ..to investigate the role of oxidative stress in the neurotoxicity of two commonly used OPs, chlorpyrifos (CPF) and diazinon (DZ), their oxygen analogs (CPO and DZO), and their "inactive" metabolites (TCP and IMP), in neuronal ..
  31. Slotkin T, Tate C, Ryde I, Levin E, Seidler F. Organophosphate insecticides target the serotonergic system in developing rat brain regions: disparate effects of diazinon and parathion at doses spanning the threshold for cholinesterase inhibition. Environ Health Perspect. 2006;114:1542-6 pubmed
    ..We exposed neonatal rats to daily doses of diazinon or parathion on postnatal days (PND)1-4 and evaluated 5HT receptors and the 5HT transporter in brainstem and ..
  32. Akturk O, Demirin H, Sutcu R, Yilmaz N, Koylu H, Altuntas I. The effects of diazinon on lipid peroxidation and antioxidant enzymes in rat heart and ameliorating role of vitamin E and vitamin C. Cell Biol Toxicol. 2006;22:455-61 pubmed
    b>Diazinon is one of the most widely used organophosphate insecticides (OPIs) in agriculture and public health programs. Reactive oxygen species (ROS) caused by OPIs may be involved in the toxicity of various pesticides...
  33. Chon T, Chung N, Kwak I, Kim J, Koh S, Lee S, et al. Movement behaviour of Medaka (Oryzias latipes) in response to sublethal treatments of diazinon and cholinesterase activity in semi-natural conditions. Environ Monit Assess. 2005;101:1-21 pubmed
    Behavioural changes of medaka (Oryzias latipes) treated with an anticholinesterase insecticide, diazinon (0.1 mg L(-1)), were continuously observed for 4 days in semi-natural conditions...
  34. Park Y, Chung N, Choi K, Cha E, Lee S, Chon T. Computational characterization of behavioral response of medaka (Oryzias latipes) treated with diazinon. Aquat Toxicol. 2005;71:215-28 pubmed
    ..Changes in the movement behaviors of medaka (Oryzias latipes) were analyzed after being treated with diazinon at a concentration of 0.1 mg/l...
  35. Osterauer R, Köhler H. Temperature-dependent effects of the pesticides thiacloprid and diazinon on the embryonic development of zebrafish (Danio rerio). Aquat Toxicol. 2008;86:485-94 pubmed publisher
    The present study examined combined effects of the insecticides thiacloprid and diazinon and a physical stressor, elevated temperature (28, 30 and 33...
  36. Girón Pérez M, Santerre A, Gonzalez Jaime F, Casas Solis J, Hernández Coronado M, Peregrina Sandoval J, et al. Immunotoxicity and hepatic function evaluation in Nile tilapia (Oreochromis niloticus) exposed to diazinon. Fish Shellfish Immunol. 2007;23:760-9 pubmed
    The LC(50) of the organophosphorus pesticides (OPs) diazinon to Nile tilapia (Oreochromis niloticus) was determined, thereafter, hepatic activity, phagocytic index, percentages of active cells, relative spleen weight, total IgM ..
  37. Tang J, Zhang M, Cheng G, Lu Y. Diazinon determination using high performance liquid chromatography: a comparison of the ENVI-Carb column with the immunoaffinity column for the pretreatment of water and soil samples. Bull Environ Contam Toxicol. 2009;83:626-9 pubmed publisher
    An immunoaffinity chromatography column was developed to remove diazinon from water and soil samples. In this paper, two types of absorbent columns, the immunoaffinity chromatography column and the ENVI-Carb column, were compared...
  38. Dutta H, Meijer H. Sublethal effects of diazinon on the structure of the testis of bluegill, Lepomis macrochirus: a microscopic analysis. Environ Pollut. 2003;125:355-60 pubmed
    A histopathological analysis of the testis exposed to diazinon, an organophosphorus pesticide was conducted...
  39. Stark J, Vargas R. Demographic changes in Daphnia pulex (Leydig) after exposure to the insecticides spinosad and diazinon. Ecotoxicol Environ Saf. 2003;56:334-8 pubmed
    ..Data were also generated for the commonly used organophosphorus insecticide diazinon as a comparison...
  40. Dahlgren J, Takhar H, Ruffalo C, Zwass M. Health effects of diazinon on a family. J Toxicol Clin Toxicol. 2004;42:579-91 pubmed
    There is increasing evidence of permanent sequalae from acute organophosphate poisoning. We report on accidental diazinon overexposure with acute organophosphate poisoning through cutaneous absorption and inhalation followed by persistent ..
  41. Gordon S, Callahan P, Nishioka M, Brinkman M, O Rourke M, Lebowitz M, et al. Residential environmental measurements in the national human exposure assessment survey (NHEXAS) pilot study in Arizona: preliminary results for pesticides and VOCs. J Expo Anal Environ Epidemiol. 1999;9:456-70 pubmed
    ..Arizona was to conduct residential environmental and biomarker measurements of selected pesticides (chlorpyrifos, diazinon), volatile organic compounds (VOCs; benzene, toluene, trichloroethene, formaldehyde, 1,3-butadiene), and metals ..
  42. Dembele K, Haubruge E, Gaspar C. Concentration effects of selected insecticides on brain acetylcholinesterase in the common carp (Cyprinus carpio L.). Ecotoxicol Environ Saf. 2000;45:49-54 pubmed
    ..present study in vivo exposure period effect and in vitro concentration-response of chlorfenvinphos, chlorpyrifos diazinon, and carbofuran were investigated on Cyprinus carpio L. AChE...
  43. Qiao D, Seidler F, Slotkin T. Developmental neurotoxicity of chlorpyrifos modeled in vitro: comparative effects of metabolites and other cholinesterase inhibitors on DNA synthesis in PC12 and C6 cells. Environ Health Perspect. 2001;109:909-13 pubmed
    ..b>Diazinon, another organophosphate pesticide, also inhibited DNA synthesis with preference toward C6 cells, but was less ..
  44. Kumar S, Paul S, Sharma A, Kumar R, Tewari S, Chaudhuri P, et al. Diazinon resistant status in Rhipicephalus (Boophilus) microplus collected from different agro-climatic regions of India. Vet Parasitol. 2011;181:274-81 pubmed publisher
    The resistance status of Rhipicephalus (Boophilus) microplus to "Diazinon" was evaluated in 20 locations situated at various agro-climatic regions of India...
  45. Habibollahi P, Ghahremani M, Azizi E, Ostad S. Multi drug resistance-1 (MDR1) expression in response to chronic diazinon exposure: an in vitro study on Caco-2 cells. Bull Environ Contam Toxicol. 2011;86:105-9 pubmed publisher
    To evaluate the effect of chronic exposure to diazinon in the gastrointestinal tract, Caco-2 cells were made resistant by growing in low concentrations of diazinon (0.02 ?M) that was gradually increased to 20 ?M within 4.5 months...
  46. Singh J, Singh D. Dehydrogenase and phosphomonoesterase activities in groundnut (Arachis hypogaea L.) field after diazinon, imidacloprid and lindane treatments. Chemosphere. 2005;60:32-42 pubmed
    Impacts of diazinon, imidacloprid and lindane treatments on dehydrogenase and alkaline phosphomonoesterase enzyme activities were determined in groundnut (Arachis hypogaea L.) field for three consecutive years (1997-1999)...
  47. Paraoanu L, Mocko J, Becker Roeck M, Smidek Huhn J, Layer P. Exposure to diazinon alters in vitro retinogenesis: retinospheroid morphology, development of chicken retinal cell types, and gene expression. Toxicol Sci. 2006;89:314-24 pubmed
    ..Therefore, the effect of the organophosphate diazinon on the development of chick retinal differentiation was studied by an in vitro reaggregate approach...
  48. Sparling D, Fellers G. Comparative toxicity of chlorpyrifos, diazinon, malathion and their oxon derivatives to larval Rana boylii. Environ Pollut. 2007;147:535-9 pubmed
    ..This study examines the toxicity of chlorpyrifos, malathion and diazinon and their oxons on the foothill yellow-legged frog (Rana boylii). R...
  49. Timchalk C, Poet T, Hinman M, Busby A, Kousba A. Pharmacokinetic and pharmacodynamic interaction for a binary mixture of chlorpyrifos and diazinon in the rat. Toxicol Appl Pharmacol. 2005;205:31-42 pubmed
    Chlorpyrifos (CPF) and diazinon (DZN) are two commonly used organophosphorus (OP) insecticides and a potential exists for concurrent exposures...
  50. Yilmaz N, Yilmaz M, Altuntas I. Diazinon-induced brain toxicity and protection by vitamins E plus C. Toxicol Ind Health. 2012;28:51-7 pubmed publisher
    b>Diazinon (DI) is a widely used pesticide in agriculture, resulting in environmental deleterious effects on neural systems...
  51. Kalender S, Ogutcu A, Uzunhisarcikli M, Açikgoz F, Durak D, Ulusoy Y, et al. Diazinon-induced hepatotoxicity and protective effect of vitamin E on some biochemical indices and ultrastructural changes. Toxicology. 2005;211:197-206 pubmed
    b>Diazinon, an organophosphate insecticide has been used in agriculture and domestic for several years...
  52. Casas E, Bonilla E, Ducolomb Y, Betancourt M. Differential effects of herbicides atrazine and fenoxaprop-ethyl, and insecticides diazinon and malathion, on viability and maturation of porcine oocytes in vitro. Toxicol In Vitro. 2010;24:224-30 pubmed publisher
    ..Atrazine and fenoxaprop-ethyl, widely used herbicides, and malathion and diazinon, organophosphate insecticides, are considered only slightly toxic to vertebrates; however, there is evidence of ..
  53. Kashanian S, Gholivand M, Ahmadi F, Ravan H. Interaction of diazinon with DNA and the protective role of selenium in DNA damage. DNA Cell Biol. 2008;27:325-32 pubmed publisher
    The interaction of native calf thymus DNA with Diazinon, an organophophorus insecticide, in HEPES buffer at neutral pH, was monitored by UV absorption spectrophotometry, circular dichroism (CD), electrochemical technique, and fluorescence ..