chlorpyrifos

Summary

Summary: An organothiophosphate cholinesterase inhibitor that is used as an insecticide and as an acaricide.

Top Publications

  1. Mansour S, Mossa A. Adverse effects of exposure to low doses of chlorpyrifos in lactating rats. Toxicol Ind Health. 2011;27:213-24 pubmed publisher
    This study was conducted to shed light on the effect of exposure of lactating rat to chlorpyrifos (CPF). CPF was orally administered to lactating rats at 0.01 mg kg(-1) b.wt. (acceptable daily intake, ADI), 1.00 mg kg(-1) b.wt...
  2. van Wendel de Joode B, Barraza D, Ruepert C, Mora A, Córdoba L, Oberg M, et al. Indigenous children living nearby plantations with chlorpyrifos-treated bags have elevated 3,5,6-trichloro-2-pyridinol (TCPy) urinary concentrations. Environ Res. 2012;117:17-26 pubmed publisher
    The US Environmental Protection Agency voluntary phased-out residential use of chlorpyrifos in 2001...
  3. Yang D, Lauridsen H, Buels K, Chi L, La Du J, Bruun D, et al. Chlorpyrifos-oxon disrupts zebrafish axonal growth and motor behavior. Toxicol Sci. 2011;121:146-59 pubmed publisher
    ..We previously demonstrated that the organophosphorus pesticide (OP) chlorpyrifos (CPF) inhibits axonal growth in cultured neurons...
  4. Kilpinen O, Kristensen M, Jensen K. Resistance differences between chlorpyrifos and synthetic pyrethroids in Cimex lectularius population from Denmark. Parasitol Res. 2011;109:1461-4 pubmed publisher
    Bed bug, Cimex lectularius L., populations were investigated for resistance against permethrin and chlorpyrifos in a topical application bioassay, after an initial establishment of a discriminating dose with a susceptible population...
  5. Yen J, Donerly S, Levin E, Linney E. Differential acetylcholinesterase inhibition of chlorpyrifos, diazinon and parathion in larval zebrafish. Neurotoxicol Teratol. 2011;33:735-41 pubmed publisher
    ..We used zebrafish to examine how exposures to three different organophosphorus pesticides (chlorpyrifos, diazinon and parathion) over the first five days of embryonic and larval development of zebrafish affected ..
  6. Lu P, Li Q, Liu H, Feng Z, Yan X, Hong Q, et al. Biodegradation of chlorpyrifos and 3,5,6-trichloro-2-pyridinol by Cupriavidus sp. DT-1. Bioresour Technol. 2013;127:337-42 pubmed publisher
    A bacterial strain, Cupriavidus sp. DT-1, capable of degrading chlorpyrifos and 3,5,6-trichloro-2-pyridinol (TCP) and using these compounds as sole carbon source was isolated and characterized...
  7. Lavado R, Schlenk D. Microsomal biotransformation of chlorpyrifos, parathion and fenthion in rainbow trout (Oncorhynchus mykiss) and coho salmon (Oncorhynchus kisutch): mechanistic insights into interspecific differences in toxicity. Aquat Toxicol. 2011;101:57-63 pubmed publisher
    ..of biotransformation in the mechanism of toxicity of three organophosphate (phosphorothionate) insecticides, (chlorpyrifos, parathion and fenthion), microsomal bioactivation and detoxification pathways were measured in gills, liver ..
  8. Basha P, Poojary A. Chlorpyrifos induced region specific vulnerability in rat CNS and modulation by age and cold stress: an interactive study. Neurochem Res. 2011;36:241-9 pubmed publisher
    b>Chlorpyrifos (CPF), an organophosphorus insecticide is known to cause ill health in non-target animals by inducing oxidative stress...
  9. Li K, Wang S, Shi Y, Qu J, Zhai Y, Xu L, et al. Genome sequence of Paracoccus sp. Strain TRP, a Chlorpyrifos Biodegrader. J Bacteriol. 2011;193:1786-7 pubmed publisher
    Paracoccus sp. strain TRP, isolated from activated sludge, could completely biodegrade chlorpyrifos and 3,5,6-trichloro-2-pyridinol. Here we report the draft genome sequence of Paracoccus sp...

More Information

Publications62

  1. Sledge D, Yen J, Morton T, Dishaw L, Petro A, Donerly S, et al. Critical duration of exposure for developmental chlorpyrifos-induced neurobehavioral toxicity. Neurotoxicol Teratol. 2011;33:742-51 pubmed publisher
    Developmental exposure of rats to the pesticide chlorpyrifos (CPF) causes persistent neurobehavioral impairment...
  2. Guiñazu N, Rena V, Genti Raimondi S, Rivero V, Magnarelli G. Effects of the organophosphate insecticides phosmet and chlorpyrifos on trophoblast JEG-3 cell death, proliferation and inflammatory molecule production. Toxicol In Vitro. 2012;26:406-13 pubmed publisher
    ..The effects of the OP phosmet (Pm) and chlorpyrifos (Cp) on JEG-3 cells viability, proliferation, cell cycle and inflammatory molecule production were evaluated...
  3. Hinderliter P, Price P, Bartels M, Timchalk C, Poet T. Development of a source-to-outcome model for dietary exposures to insecticide residues: an example using chlorpyrifos. Regul Toxicol Pharmacol. 2011;61:82-92 pubmed publisher
    ..This model was used to investigate cholinesterase inhibition from dietary exposures to an insecticide (chlorpyrifos) in populations of adults and 3 year old children...
  4. Chen S, Liu C, Peng C, Liu H, Hu M, Zhong G. Biodegradation of chlorpyrifos and its hydrolysis product 3,5,6-trichloro-2-pyridinol by a new fungal strain Cladosporium cladosporioides Hu-01. PLoS ONE. 2012;7:e47205 pubmed publisher
    Intensive use of chlorpyrifos has resulted in its ubiquitous presence as a contaminant in surface streams and soils...
  5. Pérez Parada A, Colazzo M, Besil N, Geis Asteggiante L, Rey F, Heinzen H. Determination of coumaphos, chlorpyrifos and ethion residues in propolis tinctures by matrix solid-phase dispersion and gas chromatography coupled to flame photometric and mass spectrometric detection. J Chromatogr A. 2011;1218:5852-7 pubmed publisher
    ..routine application for the quantitative analysis of a selected group of organophosphate pesticides (coumaphos, chlorpyrifos and ethion) which can be found at trace levels in propolis tinctures (ethanolic propolis extracts); a valuable ..
  6. Harwood A, Landrum P, Weston D, Lydy M. Using SPME fibers and Tenax to predict the bioavailability of pyrethroids and chlorpyrifos in field sediments. Environ Pollut. 2013;173:47-51 pubmed publisher
    ..In general, Tenax proved a more sensitive method than SPME fibers and a correlation between Tenax extractable concentrations and mortality was observed. ..
  7. Foxenberg R, Ellison C, Knaak J, Ma C, Olson J. Cytochrome P450-specific human PBPK/PD models for the organophosphorus pesticides: chlorpyrifos and parathion. Toxicology. 2011;285:57-66 pubmed publisher
    ..Phosphororthioate OPs like chlorpyrifos and parathion are directly activated and detoxified by various cytochrome P450s (CYPs), with the primary CYPs ..
  8. Xu F, Chang X, Lou D, Wu Q, Zhou Z. Chlorpyrifos exposure causes alternation in dopamine metabolism in PC12 cells. Toxicol Mech Methods. 2012;22:309-14 pubmed publisher
    b>Chlorpyrifos (CPF) is one of the organophosphorus pesticides widely used around the world, especially in China. Acetylcholinesterase inhibition is the main effect of organophosphorus insecticides exposure...
  9. Sun X, Cao Y, Gong Z, Wang X, Zhang Y, Gao J. An amperometric immunosensor based on multi-walled carbon nanotubes-thionine-chitosan nanocomposite film for chlorpyrifos detection. Sensors (Basel). 2012;12:17247-61 pubmed publisher
    ..MWCNTs-THI-CHIT) nanocomposite film as electrode modified material was developed for the detection of chlorpyrifos residues...
  10. Fenske R, Farahat F, Galvin K, Fenske E, Olson J. Contributions of inhalation and dermal exposure to chlorpyrifos dose in Egyptian cotton field workers. Int J Occup Environ Health. 2012;18:198-209 pubmed publisher
    b>Chlorpyrifos exposures were assessed in 12 Egyptian cotton field workers. 3,5,6-trichloro-2-pyridinol (TCPy) was measured in 24-hour urine samples to estimate absorbed dose...
  11. Crane A, Klein K, Olson J. Bioactivation of chlorpyrifos by CYP2B6 variants. Xenobiotica. 2012;42:1255-62 pubmed publisher
    b>Chlorpyrifos (CPF), an organophosphorus (OP) pesticide, is bioactivated by cytochrome P450s (CYPs) to the active metabolite chlorpyrifos oxon (CPF-O)...
  12. Zhang X, Shen Y, Yu X, Liu X. Dissipation of chlorpyrifos and residue analysis in rice, soil and water under paddy field conditions. Ecotoxicol Environ Saf. 2012;78:276-80 pubmed publisher
    The analytical method for the residues of chlorpyrifos in rice plants, water and soil was developed and dissipation of chlorpyrifos under field conditions was studied. The limit of detection (LOD) of chlorpyrifos was 0...
  13. Xie H, Li Q, Wang M, Zhao L. Production of a recombinant laccase from Pichia pastoris and biodegradation of chlorpyrifos in a laccase/vanillin system. J Microbiol Biotechnol. 2013;23:864-71 pubmed
    ..The enzyme could remain stable at 30°C for 5 days. The recombinant laccase was used to degrade chlorpyrifos in several laccase/mediator systems...
  14. Buono S, Manzo S, Maria G, Sansone G. Toxic effects of pentachlorophenol, azinphos-methyl and chlorpyrifos on the development of Paracentrotus lividus embryos. Ecotoxicology. 2012;21:688-97 pubmed publisher
    ..the toxic effects of three current-use pesticides, pentachlorophenol (PCP), azinphos-methyl (AZM), and chlorpyrifos, on Mediterranean sea urchin Paracentrotus lividus early development and offspring quality...
  15. Crane A, Klein K, Zanger U, Olson J. Effect of CYP2B6*6 and CYP2C19*2 genotype on chlorpyrifos metabolism. Toxicology. 2012;293:115-22 pubmed publisher
    b>Chlorpyrifos (CPF) is a widely used organophosphorus (OP) pesticide. CPF is bioactivated by cytochrome P450s (CYPs) to the potent cholinesterase inhibitor chlorpyrifos oxon (CPF-O) or detoxified to 3,5,6-trichloro-2-pyridinol (TCPy)...
  16. Crane A, Abdel Rasoul G, Ismail A, Hendy O, Bonner M, Lasarev M, et al. Longitudinal assessment of chlorpyrifos exposure and effect biomarkers in adolescent Egyptian agricultural workers. J Expo Sci Environ Epidemiol. 2013;23:356-62 pubmed publisher
    b>Chlorpyrifos (CPF) is applied seasonally in Egypt by adolescent agricultural workers and the extent of occupational exposure and the potential for environmental CPF exposure in this population is poorly understood...
  17. Ellison C, Smith J, Lein P, Olson J. Pharmacokinetics and pharmacodynamics of chlorpyrifos in adult male Long-Evans rats following repeated subcutaneous exposure to chlorpyrifos. Toxicology. 2011;287:137-44 pubmed publisher
    b>Chlorpyrifos (CPF) is a commonly used organophosphorus pesticide. Several pharmacokinetic and pharmacodynamic studies have been conducted in rats in which CPF was administered as a single bolus dose...
  18. Rauh V, Perera F, Horton M, Whyatt R, Bansal R, Hao X, et al. Brain anomalies in children exposed prenatally to a common organophosphate pesticide. Proc Natl Acad Sci U S A. 2012;109:7871-6 pubmed publisher
    Prenatal exposure to chlorpyrifos (CPF), an organophosphate insecticide, is associated with neurobehavioral deficits in humans and animal models...
  19. Zamfir L, Rotariu L, Bala C. A novel, sensitive, reusable and low potential acetylcholinesterase biosensor for chlorpyrifos based on 1-butyl-3-methylimidazolium tetrafluoroborate/multiwalled carbon nanotubes gel. Biosens Bioelectron. 2011;26:3692-5 pubmed publisher
    ..The amount of immobilized enzyme and incubation time with chlorpyrifos were optimized. Chlorpyrifos could be determined in the range of 10(-8)-10(-6)M with a detection limit of 4 nM...
  20. Li A, Lowe K, McIntosh L, Mink P. Evaluation of epidemiology and animal data for risk assessment: chlorpyrifos developmental neurobehavioral outcomes. J Toxicol Environ Health B Crit Rev. 2012;15:109-84 pubmed publisher
    Developmental neurobehavioral outcomes attributed to exposure to chlorpyrifos (CPF) obtained from epidemiologic and animal studies published before June 2010 were reviewed for risk assessment purposes...
  21. Xing H, Li S, Wang Z, Gao X, Xu S, Wang X. Histopathological changes and antioxidant response in brain and kidney of common carp exposed to atrazine and chlorpyrifos. Chemosphere. 2012;88:377-83 pubmed publisher
    ..The information presented in this study may be helpful to understanding the mechanisms of ATR-, CPF- and ATR/CPF combination-induced oxidative stress in fish. ..
  22. Dubey K, Fulekar M. Chlorpyrifos bioremediation in Pennisetum rhizosphere by a novel potential degrader Stenotrophomonas maltophilia MHF ENV20. World J Microbiol Biotechnol. 2012;28:1715-25 pubmed publisher
    ..In the present study Pennisetum pedicellatum and rhizosphere associated degrading strains were evaluated for chlorpyrifos remediation. Time-course pot experiments were conducted in greenhouse with P...
  23. Chen C, Qian Y, Liu X, Tao C, Liang Y, Li Y. Risk assessment of chlorpyrifos on rice and cabbage in China. Regul Toxicol Pharmacol. 2012;62:125-30 pubmed publisher
    b>Chlorpyrifos is a widely used organophosphorus insecticide in agricultural pest control...
  24. Krishnan K, Mitra N, Yee L, Yang H. A comparison of neurotoxicity in cerebellum produced by dermal application of chlorpyrifos in young and adult mice. J Neural Transm (Vienna). 2012;119:345-52 pubmed publisher
    b>Chlorpyrifos (CPF), an organophosphate pesticide inhibits acetylcholinesterase (AChE) and causes neuromuscular incoordination among children and elderly...
  25. Tejada M, Gómez I, Del Toro M. Use of organic amendments as a bioremediation strategy to reduce the bioavailability of chlorpyrifos insecticide in soils. Effects on soil biology. Ecotoxicol Environ Saf. 2011;74:2075-81 pubmed publisher
    ..of both an organic municipal solid waste by-product (MSW) and a cow manure (CM) in a soil polluted with chlorpyrifos, as well as its effect on soil microbial activity, and weight, reproductive parameters and glutathione-S-..
  26. Turgeman G, Pinkas A, Slotkin T, Tfilin M, Langford R, Yanai J. Reversal of chlorpyrifos neurobehavioral teratogenicity in mice by allographic transplantation of adult subventricular zone-derived neural stem cells. J Neurosci Res. 2011;89:1185-93 pubmed publisher
    ..HS/Ibg mice were exposed prenatally to chlorpyrifos on gestational days 9-18 (3 mg/kg/day, SC) in order to induce deficits in their performance in the Morris water ..
  27. Rauh V, Arunajadai S, Horton M, Perera F, Hoepner L, Barr D, et al. Seven-year neurodevelopmental scores and prenatal exposure to chlorpyrifos, a common agricultural pesticide. Environ Health Perspect. 2011;119:1196-201 pubmed publisher
    ..Columbia Center for Children's Environmental Health), we have previously reported that prenatal exposure to chlorpyrifos (CPF) was associated with neurodevelopmental problems at 3 years of age...
  28. Dondero F, Banni M, Negri A, Boatti L, Dagnino A, Viarengo A. Interactions of a pesticide/heavy metal mixture in marine bivalves: a transcriptomic assessment. BMC Genomics. 2011;12:195 pubmed publisher
    ..binary mixture made of two wide-spread pollutants: the heavy metal nickel and the organic phosphorus pesticide Chlorpyrifos. To this aim, we carried out in tissues of Mytius galloprovincialis (Lam) a systems approach based on the ..
  29. Tripathi S, Suzuki N, Srivastav A. Response of serum minerals (calcium, phosphate, and magnesium) and endocrine glands (calcitonin cells and parathyroid gland) of Wistar rat after chlorpyrifos administration. Microsc Res Tech. 2013;76:673-8 pubmed publisher
    Wistar rats (male) were daily administered chlorpyrifos at a dose of 5 mg/kg b wt. and 10 mg/kg b wt. and sacrificed on 1st, 2nd, 4th, 6th, and 8th week...
  30. Chai L, Wong M, Bruun Hansen H. Degradation of chlorpyrifos in humid tropical soils. J Environ Manage. 2013;125:28-32 pubmed publisher
    The insecticide chlorpyrifos is extensively used in the humid tropics for insect control on crops and soils...
  31. Chaou C, Lin C, Chen H, Lee C, Chen T. Chlorpyrifos is associated with slower serum cholinesterase recovery in acute organophosphate-poisoned patients. Clin Toxicol (Phila). 2013;51:402-8 pubmed publisher
    ..b>Chlorpyrifos and methamidophos had significantly slower and faster SChE recovery rates, respectively, than other ..
  32. Chen W, Ma H, Bian J, Zhang Y, Li J. Hyper-phosphorylation of GSK-3?: possible roles in chlorpyrifos-induced behavioral alterations in animal model of depression. Neurosci Lett. 2012;528:148-52 pubmed publisher
    In recent years, the widespread use of chlorpyrifos (CPF) has aroused concerns regarding its potential neurotoxic effects, especially in developing individuals...
  33. Zhang N, Liu C, Yang F, Dong S, Han Z. Resistance mechanisms to chlorpyrifos and F392W mutation frequencies in the acetylcholine esterase ace1 allele of field populations of the tobacco whitefly, Bemisia tabaci in China. J Insect Sci. 2012;12:41 pubmed publisher
    ..In China, chlorpyrifos has been used to control this insect for many years and is still being used despite the fact that some ..
  34. Chiapella G, Flores Martin J, Ridano M, Reyna L, Magnarelli de Potas G, Panzetta Dutari G, et al. The organophosphate chlorpyrifos disturbs redox balance and triggers antioxidant defense mechanisms in JEG-3 cells. Placenta. 2013;34:792-8 pubmed publisher
    ..Here, we analyzed the effect of chlorpyrifos (CPF) on the JEG-3 cell antioxidant defense in conditions where cell viability and morphology were not altered...
  35. Slotkin T, Card J, Seidler F. Chlorpyrifos developmental neurotoxicity: interaction with glucocorticoids in PC12 cells. Neurotoxicol Teratol. 2012;34:505-12 pubmed publisher
    ..neurodifferentiation in order to assess whether dexamethasone enhances the developmental neurotoxicity of chlorpyrifos, focusing on models relevant to human exposures...
  36. Saunders M, Magnanti B, Correia Carreira S, Yang A, Alamo Hernández U, Riojas Rodriguez H, et al. Chlorpyrifos and neurodevelopmental effects: a literature review and expert elicitation on research and policy. Environ Health. 2012;11 Suppl 1:S5 pubmed publisher
    ..the US for a decade due to adverse health effects, they are still the most prevalent pesticides in the EU, with Chlorpyrifos (CPF) being the most commonly applied...
  37. Lee J, Park J, Shin I, Koh H. Reactive oxygen species regulated mitochondria-mediated apoptosis in PC12 cells exposed to chlorpyrifos. Toxicol Appl Pharmacol. 2012;263:148-62 pubmed publisher
    ..In this study we found that chlorpyrifos (CPF) induced apoptosis in dopaminergic neuronal components of PC12 cells as demonstrated by the activation of ..
  38. Sasikala C, Jiwal S, Rout P, Ramya M. Biodegradation of chlorpyrifos by bacterial consortium isolated from agriculture soil. World J Microbiol Biotechnol. 2012;28:1301-8 pubmed publisher
    Organophosphorous pesticides are widely used in agriculture to control major insect pests. Chlorpyrifos is one of the major organophosphorous pesticides which is used to control insects including termites, beetles...
  39. Zafar M, van Wijngaarden R, Roessink I, Van den Brink P. Effects of time-variable exposure regimes of the insecticide chlorpyrifos on freshwater invertebrate communities in microcosms. Environ Toxicol Chem. 2011;30:1383-94 pubmed publisher
    ..exposure regimes having the same time-weighted average (TWA) concentration of the organophosphate insecticide chlorpyrifos on freshwater invertebrate communities to enable extrapolation of effects across exposure regimes...
  40. Sams C, Jones K. Human volunteer studies investigating the potential for toxicokinetic interactions between the pesticides deltamethrin; pirimicarb and chlorpyrifos-methyl following oral exposure at the acceptable daily intake. Toxicol Lett. 2011;200:41-5 pubmed publisher
    ..01 mg/kg/day) or pirimicarb (0.02 mg/kg/day) at the acceptable daily intake (ADI) together with chlorpyrifos-methyl (0...
  41. Rubach M, Ashauer R, Maund S, Baird D, Van den Brink P. Toxicokinetic variation in 15 freshwater arthropod species exposed to the insecticide chlorpyrifos. Environ Toxicol Chem. 2010;29:2225-34 pubmed publisher
    ..does this relate to differences in species sensitivity? In a series of experiments, we studied the TK of [(14)C]chlorpyrifos in 15 freshwater arthropod species, two of which were studied in juvenile and adult life stages...
  42. Phung D, Connell D, Miller G, Chu C. Probabilistic assessment of chlorpyrifos exposure to rice farmers in Viet Nam. J Expo Sci Environ Epidemiol. 2012;22:417-23 pubmed publisher
    b>Chlorpyrifos is the most common organophosphate compound registered for agricultural use in Vietnam. The aim of this study was to evaluate chlorpyrifos exposure to rice farmers in Vietnam, using a probabilistic approach...
  43. Fu Y, Li M, Liu C, Qu J, Zhu W, Xing H, et al. Effect of atrazine and chlorpyrifos exposure on cytochrome P450 contents and enzyme activities in common carp gills. Ecotoxicol Environ Saf. 2013;94:28-36 pubmed publisher
    b>Chlorpyrifos (CPF) and atrazine (ATR) are the most widely used organophosphate insecticides and triazine herbicides, respectively, worldwide...
  44. Kalender Y, Kaya S, Durak D, Uzun F, Demir F. Protective effects of catechin and quercetin on antioxidant status, lipid peroxidation and testis-histoarchitecture induced by chlorpyrifos in male rats. Environ Toxicol Pharmacol. 2012;33:141-8 pubmed publisher
    Mature male Wistar rats were given chlorpyrifos (5.4 mg/kg, 1/25 of the oral LD(50)), catechin (20 mg/kg),quercetin (20 mg/kg), catechin plus chlorpyrifos, and quercetin plus chlorpyrifos daily via gavage for four weeks...
  45. Rivadeneira P, Agrelo M, Otero S, Kristoff G. Different effects of subchronic exposure to low concentrations of the organophosphate insecticide chlorpyrifos in a freshwater gastropod. Ecotoxicol Environ Saf. 2013;90:82-8 pubmed publisher
    b>Chlorpyrifos is an organophosphate insecticide used for pest control on a number of food crops in many parts of the world. In recent years, there has been an important decrease in the number of organisms of Planorbarius corneus...
  46. Prueitt R, Goodman J, Bailey L, Rhomberg L. Hypothesis-based weight-of-evidence evaluation of the neurodevelopmental effects of chlorpyrifos. Crit Rev Toxicol. 2011;41:822-903 pubmed publisher
    ..a hypothesis-based weight-of-evidence (HBWoE) approach to analyze the evidence regarding the hypothesis that chlorpyrifos can cause neurodevelopmental effects below the threshold for inhibition of acetylcholinesterase activity in the ..
  47. Kadian N, Malik A, Satya S, Dureja P. Effect of organic amendments on microbial activity in chlorpyrifos contaminated soil. J Environ Manage. 2012;95 Suppl:S199-202 pubmed publisher
    The aim of this research was to study the inhibitory effect of chlorpyrifos (CPF) on soil microbial activity and to evaluate the efficacy of different organic amendments as a biostimulation agent for sustaining the microbial activity and ..
  48. Estevan C, Vilanova E, Sogorb M. Chlorpyrifos and its metabolites alter gene expression at non-cytotoxic concentrations in D3 mouse embryonic stem cells under in vitro differentiation: considerations for embryotoxic risk assessment. Toxicol Lett. 2013;217:14-22 pubmed publisher
    The effects of organophosphate insecticide chlorpyrifos (CPF) on development are currently under discussion...
  49. Rubach M, Crum S, Van den Brink P. Variability in the dynamics of mortality and immobility responses of freshwater arthropods exposed to chlorpyrifos. Arch Environ Contam Toxicol. 2011;60:708-21 pubmed publisher
    ..the relevance of immobilization and mortality as end points for effects of the organophosphate insecticide chlorpyrifos on 14 freshwater arthropods in the context of ERA...
  50. Viñuela A, Snoek L, Riksen J, Kammenga J. Genome-wide gene expression analysis in response to organophosphorus pesticide chlorpyrifos and diazinon in C. elegans. PLoS ONE. 2010;5:e12145 pubmed publisher
    ..elegans which was exposed for 72 hrs to two widely used Ops, chlorpyrifos and diazinon, and a low dose mixture of these two compounds...
  51. Joly C, Gay Quéheillard J, Léké A, Chardon K, Delanaud S, Bach V, et al. Impact of chronic exposure to low doses of chlorpyrifos on the intestinal microbiota in the Simulator of the Human Intestinal Microbial Ecosystem (SHIME) and in the rat. Environ Sci Pollut Res Int. 2013;20:2726-34 pubmed publisher
    The impact of the insecticide chlorpyrifos (CPF) on the mammalian digestive system has been poorly described...
  52. Cacciatore L, Kristoff G, Verrengia Guerrero N, Cochón A. Binary mixtures of azinphos-methyl oxon and chlorpyrifos oxon produce in vitro synergistic cholinesterase inhibition in Planorbarius corneus. Chemosphere. 2012;88:450-8 pubmed publisher
    ..Secondly, the effects of azinphos-methyl oxon (AZM-oxon) and chlorpyrifos oxon (CPF-oxon), the active oxygen analogs of the OP insecticides AZM and CPF, on ChE and CES activities were ..
  53. Venerosi A, Ricceri L, Tait S, Calamandrei G. Sex dimorphic behaviors as markers of neuroendocrine disruption by environmental chemicals: the case of chlorpyrifos. Neurotoxicology. 2012;33:1420-6 pubmed publisher
    ..on the neurobehavioral effects of developmental exposure to the non-persistent organophosphorus insecticide chlorpyrifos, whose neurotoxic activity at low doses is currently a matter of concern for children's health...