dietary sodium

Summary

Summary: Sodium or sodium compounds used in foods or as a food. The most frequently used compounds are sodium chloride or sodium glutamate.

Top Publications

  1. Frindt G, Palmer L. Surface expression of sodium channels and transporters in rat kidney: effects of dietary sodium. Am J Physiol Renal Physiol. 2009;297:F1249-55 pubmed publisher
    ..We conclude that cleavage of gamma-ENaC and its expression at the apical surface play a major role in the regulation of renal Na reabsorption...
  2. Barr S. Reducing dietary sodium intake: the Canadian context. Appl Physiol Nutr Metab. 2010;35:1-8 pubmed publisher
    ..men and two thirds of Canadian women have sodium intakes above the UL, Health Canada's Working Group on Dietary Sodium Reduction has been charged with developing, implementing, and overseeing a strategy to reduce Canadians' ..
  3. Williams J, Solomon S, Crivaro M, Conlin P. Dietary sodium intake modulates myocardial relaxation responsiveness to angiotensin II. Transl Res. 2006;148:49-54 pubmed
    b>Dietary sodium alters renovascular responsiveness to angiotensin II (Ang II) in normal subjects. Evidence supports a connection among dietary sodium, the rennin-angiotensin system, and myocardial function...
  4. Al Awqati Q. Evidence-based politics of salt and blood pressure. Kidney Int. 2006;69:1707-8 pubmed
  5. Loffing Cueni D, Flores S, Sauter D, DaidiƩ D, Siegrist N, Meneton P, et al. Dietary sodium intake regulates the ubiquitin-protein ligase nedd4-2 in the renal collecting system. J Am Soc Nephrol. 2006;17:1264-74 pubmed
    ..It is concluded that Nedd4-2 abundance is regulated by Na(+) diet, by a mechanism that likely involves aldosterone. This regulation may contribute to adaptation of apical ENaC activity to altered Na(+) intake...
  6. Liu Z. Dietary sodium and the incidence of hypertension in the Chinese population: a review of nationwide surveys. Am J Hypertens. 2009;22:929-33 pubmed publisher
    ..High dietary salt consumption is considered a risk factor for hypertension...
  7. Umesawa M, Iso H, Date C, Yamamoto A, Toyoshima H, Watanabe Y, et al. Relations between dietary sodium and potassium intakes and mortality from cardiovascular disease: the Japan Collaborative Cohort Study for Evaluation of Cancer Risks. Am J Clin Nutr. 2008;88:195-202 pubmed
    ..Limited evidence is available about the relations between sodium and potassium intakes and cardiovascular disease in the general population...
  8. Heaney R. Role of dietary sodium in osteoporosis. J Am Coll Nutr. 2006;25:271S-276S pubmed
    ..Given the relative difficulty of the former, and the ancillary benefits of the latter, it would seem that the optimal strategy to protect the skeleton is to ensure adequate calcium and potassium intakes...
  9. Bealer S, Metcalf C, Heyborne R. Increased dietary sodium alters Fos expression in the lamina terminalis during intravenous angiotensin II infusion. Exp Neurol. 2007;204:299-306 pubmed
    These studies examined the effects of increased dietary sodium on expression of Fos, the protein product of c-fos, in forebrain structures in the rat following intravenous infusion with angiotensin II (AngII)...
  10. Aoi W, Niisato N, Sawabe Y, Miyazaki H, Tokuda S, Nishio K, et al. Abnormal expression of ENaC and SGK1 mRNA induced by dietary sodium in Dahl salt-sensitively hypertensive rats. Cell Biol Int. 2007;31:1288-91 pubmed
    ..the kidney of Dahl salt-sensitive (DS) rats was abnormally regulated by aldosterone, however it is unknown if dietary sodium affects the expression of ENaC and serum and glucocorticoid-regulated kinase 1 (SGK1), which plays an ..

Detail Information

Publications62

  1. Frindt G, Palmer L. Surface expression of sodium channels and transporters in rat kidney: effects of dietary sodium. Am J Physiol Renal Physiol. 2009;297:F1249-55 pubmed publisher
    ..We conclude that cleavage of gamma-ENaC and its expression at the apical surface play a major role in the regulation of renal Na reabsorption...
  2. Barr S. Reducing dietary sodium intake: the Canadian context. Appl Physiol Nutr Metab. 2010;35:1-8 pubmed publisher
    ..men and two thirds of Canadian women have sodium intakes above the UL, Health Canada's Working Group on Dietary Sodium Reduction has been charged with developing, implementing, and overseeing a strategy to reduce Canadians' ..
  3. Williams J, Solomon S, Crivaro M, Conlin P. Dietary sodium intake modulates myocardial relaxation responsiveness to angiotensin II. Transl Res. 2006;148:49-54 pubmed
    b>Dietary sodium alters renovascular responsiveness to angiotensin II (Ang II) in normal subjects. Evidence supports a connection among dietary sodium, the rennin-angiotensin system, and myocardial function...
  4. Al Awqati Q. Evidence-based politics of salt and blood pressure. Kidney Int. 2006;69:1707-8 pubmed
  5. Loffing Cueni D, Flores S, Sauter D, DaidiƩ D, Siegrist N, Meneton P, et al. Dietary sodium intake regulates the ubiquitin-protein ligase nedd4-2 in the renal collecting system. J Am Soc Nephrol. 2006;17:1264-74 pubmed
    ..It is concluded that Nedd4-2 abundance is regulated by Na(+) diet, by a mechanism that likely involves aldosterone. This regulation may contribute to adaptation of apical ENaC activity to altered Na(+) intake...
  6. Liu Z. Dietary sodium and the incidence of hypertension in the Chinese population: a review of nationwide surveys. Am J Hypertens. 2009;22:929-33 pubmed publisher
    ..High dietary salt consumption is considered a risk factor for hypertension...
  7. Umesawa M, Iso H, Date C, Yamamoto A, Toyoshima H, Watanabe Y, et al. Relations between dietary sodium and potassium intakes and mortality from cardiovascular disease: the Japan Collaborative Cohort Study for Evaluation of Cancer Risks. Am J Clin Nutr. 2008;88:195-202 pubmed
    ..Limited evidence is available about the relations between sodium and potassium intakes and cardiovascular disease in the general population...
  8. Heaney R. Role of dietary sodium in osteoporosis. J Am Coll Nutr. 2006;25:271S-276S pubmed
    ..Given the relative difficulty of the former, and the ancillary benefits of the latter, it would seem that the optimal strategy to protect the skeleton is to ensure adequate calcium and potassium intakes...
  9. Bealer S, Metcalf C, Heyborne R. Increased dietary sodium alters Fos expression in the lamina terminalis during intravenous angiotensin II infusion. Exp Neurol. 2007;204:299-306 pubmed
    These studies examined the effects of increased dietary sodium on expression of Fos, the protein product of c-fos, in forebrain structures in the rat following intravenous infusion with angiotensin II (AngII)...
  10. Aoi W, Niisato N, Sawabe Y, Miyazaki H, Tokuda S, Nishio K, et al. Abnormal expression of ENaC and SGK1 mRNA induced by dietary sodium in Dahl salt-sensitively hypertensive rats. Cell Biol Int. 2007;31:1288-91 pubmed
    ..the kidney of Dahl salt-sensitive (DS) rats was abnormally regulated by aldosterone, however it is unknown if dietary sodium affects the expression of ENaC and serum and glucocorticoid-regulated kinase 1 (SGK1), which plays an ..
  11. Joffres M, Campbell N, Manns B, Tu K. Estimate of the benefits of a population-based reduction in dietary sodium additives on hypertension and its related health care costs in Canada. Can J Cardiol. 2007;23:437-43 pubmed
    ..Reductions in dietary sodium additives significantly lower systolic and diastolic blood pressure, and population reductions in dietary ..
  12. Dickinson B, Havas S. Reducing the population burden of cardiovascular disease by reducing sodium intake: a report of the Council on Science and Public Health. Arch Intern Med. 2007;167:1460-8 pubmed
    ..In the continued absence of voluntary measures adopted by the food industry, new regulations will be required to achieve lower sodium concentrations in processed and prepared foods...
  13. Fonseca Alaniz M, Brito L, Borges Silva C, Takada J, Andreotti S, Lima F. High dietary sodium intake increases white adipose tissue mass and plasma leptin in rats. Obesity (Silver Spring). 2007;15:2200-8 pubmed
    ..Salt restriction has been reported to increase white adipose tissue (WAT) mass in rodents. The objective of this study was to investigate the effect of different sodium content diets on the lipogenic and lipolytic activities of WAT...
  14. Bodyak N, Ayus J, Achinger S, Shivalingappa V, Ke Q, Chen Y, et al. Activated vitamin D attenuates left ventricular abnormalities induced by dietary sodium in Dahl salt-sensitive animals. Proc Natl Acad Sci U S A. 2007;104:16810-5 pubmed
    ..In summary, PC attenuates the development of LV alterations in DSS rats, and these effects should be examined in human clinical trials...
  15. Penz E, Joffres M, Campbell N. Reducing dietary sodium and decreases in cardiovascular disease in Canada. Can J Cardiol. 2008;24:497-1 pubmed
    Increases in dietary sodium increase blood pressure, whereas emerging evidence confirms that the reduction in dietary sodium results in reduced cardiovascular events.
  16. Stoller M, Chi T, Eisner B, Shami G, Gentle D. Changes in urinary stone risk factors in hypocitraturic calcium oxalate stone formers treated with dietary sodium supplementation. J Urol. 2009;181:1140-4 pubmed publisher
    We investigated the effects of supplemental dietary sodium on risk factors for urinary stone disease in stone forming patients with hypocitraturia.
  17. Houghton B, Huang C, Johns E. Influence of dietary sodium on the blood pressure and renal sympathetic nerve activity responses to intracerebroventricular angiotensin II and angiotensin III in anaesthetized rats. Exp Physiol. 2010;95:282-95 pubmed publisher
    ..c.v. AngII and AngIII; (2) highlight an important role for peripheral V(1) receptors during these responses; and (3) differentiate the effects of AngII and AngIII on blood pressure and RSNA...
  18. McNeely J, Windham B, Anderson D. Dietary sodium effects on heart rate variability in salt sensitivity of blood pressure. Psychophysiology. 2008;45:405-11 pubmed
    High dietary sodium intake is a risk factor for hypertension, and heart rate variability (HRV) is decreased in hypertension. Effects of dietary sodium intake on HRV of normotensive persons have not, however, been investigated to date...
  19. Cohen H, Hailpern S, Alderman M. Sodium intake and mortality follow-up in the Third National Health and Nutrition Examination Survey (NHANES III). J Gen Intern Med. 2008;23:1297-302 pubmed publisher
    ..Sodium restriction is commonly recommended as a measure to lower blood pressure and thus reduce cardiovascular disease (CVD) and all-cause mortality. However, some studies have observed higher mortality associated with lower sodium intake...
  20. Waanders F, Vaidya V, van Goor H, Leuvenink H, Damman K, Hamming I, et al. Effect of renin-angiotensin-aldosterone system inhibition, dietary sodium restriction, and/or diuretics on urinary kidney injury molecule 1 excretion in nondiabetic proteinuric kidney disease: a post hoc analysis of a randomized controlled trial. Am J Kidney Dis. 2009;53:16-25 pubmed publisher
    ..We hypothesized that a decrease in proteinuria by using therapeutic interventions is associated with decreased urinary KIM-1 levels...
  21. Gu D, Rice T, Wang S, Yang W, Gu C, Chen C, et al. Heritability of blood pressure responses to dietary sodium and potassium intake in a Chinese population. Hypertension. 2007;50:116-22 pubmed
    ..We examined the heritability of blood pressure responses to dietary sodium and potassium intake in a family feeding study among 1906 study participants living in rural North China...
  22. Alderman M. Evidence relating dietary sodium to cardiovascular disease. J Am Coll Nutr. 2006;25:256S-261S pubmed
    The expectation that dietary sodium intake might influence cardiovascular disease occurrence has been based upon its impact on blood pressure (BP)...
  23. Pimenta E, Gaddam K, Oparil S, Aban I, Husain S, Dell Italia L, et al. Effects of dietary sodium reduction on blood pressure in subjects with resistant hypertension: results from a randomized trial. Hypertension. 2009;54:475-81 pubmed publisher
    Observational studies indicate a significant relation between dietary sodium and level of blood pressure. However, the role of salt sensitivity in the development of resistant hypertension is unknown...
  24. Mickleborough T, Fogarty A. Dietary sodium intake and asthma: an epidemiological and clinical review. Int J Clin Pract. 2006;60:1616-24 pubmed
    ..factors that may have contributed to the rise in the prevalence of asthma over the past few decades, and dietary sodium has been considered to be a dietary constituent which may be implicated in this phenomenon...
  25. Aanen M, Bredenoord A, Smout A. Effect of dietary sodium chloride on gastro-oesophageal reflux: a randomized controlled trial. Scand J Gastroenterol. 2006;41:1141-6 pubmed
    ..The objective of this study was to investigate the effect of increased dietary NaCl intake on gastro-oesophageal reflux and reflux mechanisms...
  26. Lu B, Yang X, Chen K, Yang D, Yan J. Dietary sodium deprivation evokes activation of brain regional neurons and down-regulation of angiotensin II type 1 receptor and angiotensin-convertion enzyme mRNA expression. Neuroscience. 2009;164:1303-11 pubmed publisher
    ..system (RAAS) is implicated in the induction of sodium appetite in rats and that different dietary sodium intakes influence the mRNA expression of central and peripheral RAAS components...
  27. Reinivuo H, Valsta L, Laatikainen T, Tuomilehto J, Pietinen P. Sodium in the Finnish diet: II trends in dietary sodium intake and comparison between intake and 24-h excretion of sodium. Eur J Clin Nutr. 2006;60:1160-7 pubmed
    To estimate cross-sectional and long-term dietary sodium intakes and sources in Finland, and to evaluate the validity of 48-h recall to assess sodium intake.
  28. Logan A. Dietary sodium intake and its relation to human health: a summary of the evidence. J Am Coll Nutr. 2006;25:165-9 pubmed
  29. Parrinello G, Di Pasquale P, Licata G, Torres D, Giammanco M, Fasullo S, et al. Long-term effects of dietary sodium intake on cytokines and neurohormonal activation in patients with recently compensated congestive heart failure. J Card Fail. 2009;15:864-73 pubmed publisher
    ..A growing body of evidence suggests that the fluid accumulation plays a key role in the pathophysiology of heart failure (HF) and that the inflammatory and neurohormonal activation contribute strongly to the progression of this disorder...
  30. Papadakis S, Pipe A, Moroz I, Reid R, Blanchard C, Cote D, et al. Knowledge, attitudes and behaviours related to dietary sodium among 35- to 50-year-old Ontario residents. Can J Cardiol. 2010;26:e164-9 pubmed
    Excessive consumption of dietary sodium is an important public health issue. Little is known about the knowledge, attitudes and behaviours related to sodium consumption among Canadians.
  31. Alderman M. Presidential Address: 21st Scientific Meeting of the International Society of Hypertension: dietary sodium and cardiovascular disease: the 'J'-shaped relation. J Hypertens. 2007;25:903-7 pubmed
  32. Mimran A, du Cailar G. Dietary sodium: the dark horse amongst cardiovascular and renal risk factors. Nephrol Dial Transplant. 2008;23:2138-41 pubmed publisher
  33. Hollenberg N. The influence of dietary sodium on blood pressure. J Am Coll Nutr. 2006;25:240S-246S pubmed
    ..On the bright side, prognosis is improved substantially by the array of antihypertensive drugs available today...
  34. du Cailar G, Ribstein J, Mimran A. Dietary sodium and target organ damage in essential hypertension. Am J Hypertens. 2002;15:222-9 pubmed
    In addition to its widely contested influence on arterial pressure, dietary sodium may exert some nonpressure-related effects on left ventricular mass in humans...
  35. Lantelme P, Rohrwasser A, Gociman B, Hillas E, Cheng T, Petty G, et al. Effects of dietary sodium and genetic background on angiotensinogen and Renin in mouse. Hypertension. 2002;39:1007-14 pubmed
    ..The response of this tubular renin-angiotensin system to stepwise changes in dietary sodium was investigated in 2 mouse strains, the sodium-sensitive inbred C57BL/6 and the sodium-resistant CD1 outbred...
  36. Dengel D, Brown M, Reynolds T, Kuskowski M, Supiano M. Effect of aerobic exercise training on blood pressure sensitivity to dietary sodium in older hypertensives. J Hum Hypertens. 2006;20:372-8 pubmed
    ..exercise training has been shown to lower blood pressure (BP) in older adults, its effect on BP sensitivity to dietary sodium (Na(+)) is unknown...
  37. He F, MacGregor G. How far should salt intake be reduced?. Hypertension. 2003;42:1093-9 pubmed
    ..A further reduction to 3 g/d will have a much greater effect and should now become the long-term target for population salt intake worldwide...
  38. Havas S, Roccella E, Lenfant C. Reducing the public health burden from elevated blood pressure levels in the United States by lowering intake of dietary sodium. Am J Public Health. 2004;94:19-22 pubmed
    ..Such a reduction would greatly enhance the chances of attaining the Healthy People 2010 objectives and would save at least 150 000 lives annually. This issue warrants public health intervention...
  39. Teucher B, Fairweather Tait S. Dietary sodium as a risk factor for osteoporosis: where is the evidence?. Proc Nutr Soc. 2003;62:859-66 pubmed
    ..g. salt sensitivity). The reasons for inter-individual variability should be explored using post-genomic techniques...
  40. Adeyemo A, Prewitt T, Luke A, Omotade O, Rotimi C, Brieger W, et al. The feasibility of implementing a dietary sodium reduction intervention among free-living normotensive individuals in south west Nigeria. Ethn Dis. 2002;12:207-12 pubmed
    ..In this study, we tested the feasibility of achieving a reduction in dietary sodium intake in free-living individuals using a dietary intervention among 82 free-living normotensive adults in ..
  41. Geleijnse J, Kok F, Grobbee D. Blood pressure response to changes in sodium and potassium intake: a metaregression analysis of randomised trials. J Hum Hypertens. 2003;17:471-80 pubmed
    ..51 vs -0.34 mmHg, P=0.074). In conclusion, reduced intake of sodium and increased intake of potassium could make an important contribution to the prevention of hypertension, especially in populations with elevated blood pressure...
  42. Bagrov A, Lakatta E. The dietary sodium-blood pressure plot "stiffens". Hypertension. 2004;44:22-4 pubmed
  43. Welch J, Bennett S, Delp R, Agarwal R. Benefits of and barriers to dietary sodium adherence. West J Nurs Res. 2006;28:162-80; discussion 181-9 pubmed
    Failure to limit dietary sodium leads to thirst, large fluid weight gain, and poor outcomes in patients receiving hemodialysis...
  44. Hawthorne A, Markwell P. Dietary sodium promotes increased water intake and urine volume in cats. J Nutr. 2004;134:2128S-2129S pubmed publisher
  45. Jacob F, Ariza P, Osborn J. Renal denervation chronically lowers arterial pressure independent of dietary sodium intake in normal rats. Am J Physiol Heart Circ Physiol. 2003;284:H2302-10 pubmed
    ..Overall, there were no between-group differences in sodium or water balance in either protocol. We conclude that renal nerves support basal levels of AP, irrespective of dietary sodium intake in normal rats.
  46. Kocks M, Buikema H, Gschwend S, Boomsma F, de Zeeuw D, Navis G. High dietary sodium blunts affects of angiotensin-converting enzyme inhibition on vascular angiotensin I-to-angiotensin II conversion in rats. J Cardiovasc Pharmacol. 2003;42:601-6 pubmed
    ..To investigate whether high-dietary sodium-induced effects on vascular conversion of Ang I might be involved in the sodium-induced blunting of the ..
  47. Ni X, Bhargava A, Pearce D, Humphreys M. Modulation by dietary sodium intake of melanocortin 3 receptor mRNA and protein abundance in the rat kidney. Am J Physiol Regul Integr Comp Physiol. 2006;290:R560-7 pubmed
    ..001). No significant increase occurred in the cortex. The increase in MC3-R expression induced by dietary sodium was observed in inner medullary collecting duct (IMCD) cells isolated from the kidneys of HSD rats, suggesting ..
  48. Hamming I, Navis G, Kocks M, van Goor H. ACE inhibition has adverse renal effects during dietary sodium restriction in proteinuric and healthy rats. J Pathol. 2006;209:129-39 pubmed
    ..Further studies should elucidate the mechanisms underlying these observations and their impact on long-term renoprotection...
  49. Adamczak M, Kokot F, Chudek J, Wiecek A. Effect of renin-angiotensin system activation by dietary sodium restriction and upright position on plasma leptin concentration in patients with essential hypertension. Med Sci Monit. 2002;8:CR473-7 pubmed
    ..This study was undertaken to assess the relationship between RAS and plasma leptin concentration in hypertensive patients under conditions of normal and restricted sodium supply and upright position...
  50. DiBona G. Central angiotensin modulation of baroreflex control of renal sympathetic nerve activity in the rat: influence of dietary sodium. Acta Physiol Scand. 2003;177:285-9 pubmed
    ..an intact blood-brain barrier to assess the role of endogenous angII of brain origin and (c) alterations in dietary sodium intake, a known physiological regulator of activity of the renin-angiotensin system (RAS), to assess the ..
  51. Harsha D, Sacks F, Obarzanek E, Svetkey L, Lin P, Bray G, et al. Effect of dietary sodium intake on blood lipids: results from the DASH-sodium trial. Hypertension. 2004;43:393-8 pubmed
    ..There were no significant interactions between the effects of sodium and the DASH diet on serum lipids. In conclusion, changes in dietary sodium intake over the range of 50 to 150 mmol/d did not affect blood lipid concentrations.
  52. Verhave J, Hillege H, Burgerhof J, Janssen W, Gansevoort R, Navis G, et al. Sodium intake affects urinary albumin excretion especially in overweight subjects. J Intern Med. 2004;256:324-30 pubmed
    ..To examine the relationship between sodium intake and urinary albumin excretion, being an established risk marker for later cardiovascular morbidity and mortality...
  53. Okamoto M, Sumida D, Carvalho C, Vargas A, Heimann J, Schaan B, et al. Changes in dietary sodium consumption modulate GLUT4 gene expression and early steps of insulin signaling. Am J Physiol Regul Integr Comp Physiol. 2004;286:R779-85 pubmed
    ..In the present study we investigated the influence of dietary sodium on 1) GLUT4 gene expression, by No the n and Western blotting analysis; 2) in vivo GLUT4 protein translocation,..
  54. Ohkita M, Wang Y, Nguyen N, Tsai Y, Williams S, Wiseman R, et al. Extrarenal ETB plays a significant role in controlling cardiovascular responses to high dietary sodium in rats. Hypertension. 2005;45:940-6 pubmed
    ..caused by an absence of renal ET(B) signaling and performed a series of experiments to examine the effect of dietary sodium (Na) on endothelin-1 (ET1) expression and renal function in wild-type (WT) and ET(B)-deficient rats...
  55. Bentley B. A review of methods to measure dietary sodium intake. J Cardiovasc Nurs. 2006;21:63-7 pubmed
    With the rising prevalence of heart failure, it is imperative to investigate reasons for dietary sodium nonadherence and to develop evidence-based interventions to promote adherence...
  56. Nagata C, Takatsuka N, Shimizu N, Shimizu H. Sodium intake and risk of death from stroke in Japanese men and women. Stroke. 2004;35:1543-7 pubmed
    ..The purpose of this study was to examine the relation between sodium intake and death from stroke in a population-based cohort of Japanese men and women...
  57. Gates P, Tanaka H, Hiatt W, Seals D. Dietary sodium restriction rapidly improves large elastic artery compliance in older adults with systolic hypertension. Hypertension. 2004;44:35-41 pubmed
    We determined the temporal effects of dietary sodium restriction on large elastic artery compliance and systolic blood pressure (SBP) in 12 untreated, older (64+/-2 years) men and women (6 each) with stage 1 systolic hypertension...
  58. Bray G, Vollmer W, Sacks F, Obarzanek E, Svetkey L, Appel L. A further subgroup analysis of the effects of the DASH diet and three dietary sodium levels on blood pressure: results of the DASH-Sodium Trial. Am J Cardiol. 2004;94:222-7 pubmed
  59. Bie P. Blood volume, blood pressure and total body sodium: internal signalling and output control. Acta Physiol (Oxf). 2009;195:187-96 pubmed publisher
    ..The latter indicates an essential role of the MD mechanism and/or a fourth mediator of the physiological control of renin secretion...
  60. Grimm P, Irsik D, Liu L, Holtzclaw J, Sansom S. Role of BKbeta1 in Na+ reabsorption by cortical collecting ducts of Na+-deprived mice. Am J Physiol Renal Physiol. 2009;297:F420-8 pubmed publisher
    ..We conclude that part of the mechanism to maximize Na(+) reabsorption during Na(+) deficiency is the placement of BKalpha/beta1 channels in the BSM of CCD PCs...
  61. Krikken J, Lely A, Bakker S, Navis G. The effect of a shift in sodium intake on renal hemodynamics is determined by body mass index in healthy young men. Kidney Int. 2007;71:260-5 pubmed
    ..Consequently, HS elicited a hyperfiltration pattern in subjects with a BMI>or=25 kg/m2 that was absent during LS. Future studies should elucidate whether LS or diuretics can ameliorate the long-term renal risks of weight excess...
  62. Kalaitzis C, Giannakopoulos S, Pantazis T, Pasadakis P, Touloupidis S. Role of eicosanoids of the contralateral kidney in maintenance of two-kidney, one-clip renovascular hypertension in rats. Scand J Urol Nephrol. 2007;41:362-6 pubmed
    ..To elucidate the role of the eicosanoids prostaglandin E(2) (PGE(2)), 6-keto-prostaglandin F(1a) (PGF(1a)) and thromboxane B(2) (TXB(2)) in the maintenance of two-kidney, one-clip renovascular hypertension in rats...