phosphorous acids

Summary

Summary: Inorganic derivatives of phosphorus trihydroxide (P(OH)3) and its tautomeric form dihydroxyphosphine oxide (HP=O(OH)2). Note that organic derivatives of phosphonic acids are listed under are ORGANOPHOSPHONATES.

Top Publications

  1. Lok A, Trinh H, Carosi G, Akarca U, Gadano A, Habersetzer F, et al. Efficacy of entecavir with or without tenofovir disoproxil fumarate for nucleos(t)ide-naïve patients with chronic hepatitis B. Gastroenterology. 2012;143:619-628.e1 pubmed publisher
    ..We compared the efficacy and safety of ETV monotherapy with those of a combination of ETV and TDF...
  2. Chan L, Meng X, Kim S. ortho-Acetoxylation of phosphonic and phosphoric monoacids via Pd(II) catalysis. J Org Chem. 2013;78:8826-32 pubmed publisher
    ..A simple and efficient method is developed for Pd-catalyzed ortho-acetoxylation using organophosphates, namely, benzylic phosphonic and aryl phosphoric monoacids, as the directing group. ..
  3. Sato Y, Uchiki T, Iwama M, Kishimoto Y, Takahashi R, Ishigami A. Determination of dehydroascorbic acid in mouse tissues and plasma by using tris(2-carboxyethyl)phosphine hydrochloride as reductant in metaphosphoric acid/ethylenediaminetetraacetic acid solution. Biol Pharm Bull. 2010;33:364-9 pubmed
    ..This difference in DHA content may indicate an important disparity of oxidative stress levels among physiologic sites. Therefore, this improved method provides a useful standard for all DHA determinations. ..
  4. Subramaniam R, Ostin A, Nilsson C, Astot C. Direct derivatization and gas chromatography-tandem mass spectrometry identification of nerve agent biomarkers in urine samples. J Chromatogr B Analyt Technol Biomed Life Sci. 2013;928:98-105 pubmed publisher
    ..The method thus offers excellent performance and is viable for the simultaneous trace determination of a wide range of nerve agent markers. ..
  5. Kim K, Hong J. Efficient electrophilic fluorination for the synthesis of novel 2'-fluoro-3'-methyl-5'-deoxyphosphonic acid apiosyl nucleoside analogues. Nucleosides Nucleotides Nucleic Acids. 2013;32:555-70 pubmed publisher
    ..The synthesized nucleoside analogues were subjected to antiviral screening against HIV-1, and the adenine analogue 17 exhibited weak in vitro anti-HIV-1 activity (EC50=26.6 ?M). ..
  6. Blumenthal J, Haubrich R. Pre-exposure prophylaxis for HIV infection: how antiretroviral pharmacology helps to monitor and improve adherence. Expert Opin Pharmacother. 2013;14:1777-85 pubmed publisher
  7. Han X, Sun S, He T. Preparation and photolithography of self-assembled monolayers of 10-mercaptodecanylphosphonic acid on glass mediated by zirconium for protein patterning. Colloids Surf B Biointerfaces. 2013;108:66-71 pubmed publisher
    ..The present strategy, which combined the SAMs assembly and photolithography, offered a facile approach for the fabrication of biomolecule patterning and could be applied to construction of biochips and other applications. ..
  8. Demmer C, Krogsgaard Larsen N, Bunch L. Review on modern advances of chemical methods for the introduction of a phosphonic acid group. Chem Rev. 2011;111:7981-8006 pubmed publisher
  9. Chan H, Chan C, Hui A, Chan S, Poordad F, Chang T, et al. Effects of tenofovir disoproxil fumarate in hepatitis B e antigen-positive patients with normal levels of alanine aminotransferase and high levels of hepatitis B virus DNA. Gastroenterology. 2014;146:1240-8 pubmed publisher
    ..We evaluated the effects of single and combination therapies in immune-tolerant patients with chronic hepatitis B...

More Information

Publications100

  1. Bassi A, Gough J, Downes S. A novel phosphonate for the repair of critical size bone defects. J Tissue Eng Regen Med. 2012;6:833-40 pubmed publisher
    ..In conclusion, this study showed that the PCL/PVPA scaffold is a novel system that has the potential for use as a bone graft substitute and in assisting in the healing of critical size defects. ..
  2. He Y, Zhang B. [Quantitative determination of glass content in monazite glass-ceramics by IR technique]. Guang Pu Xue Yu Guang Pu Fen Xi. 2003;23:262-5 pubmed
    ..9917 and a regression equation y = 0.2211 exp (0.0221x). High correlation coefficients show that the IR technique could find new application in the quantitative analysis of glass content in phosphate glass-ceramics. ..
  3. Tourret J, Deray G, Isnard Bagnis C. Tenofovir effect on the kidneys of HIV-infected patients: a double-edged sword?. J Am Soc Nephrol. 2013;24:1519-27 pubmed publisher
    ..Here we review the differences in patient characteristics, study designs, and measured outcomes that can possibly explain these conflicting findings. We conclude with rational recommendation for appropriate TDF prescription. ..
  4. Fernández Martín J, Carrero J, Benedik M, Bos W, Covic A, Ferreira A, et al. COSMOS: the dialysis scenario of CKD-MBD in Europe. Nephrol Dial Transplant. 2013;28:1922-35 pubmed publisher
    ..The COSMOS baseline results show important differences across Europe in the management of CKD-MBD. ..
  5. Ebert D, Bhushan B. Wear-resistant rose petal-effect surfaces with superhydrophobicity and high droplet adhesion using hydrophobic and hydrophilic nanoparticles. J Colloid Interface Sci. 2012;384:182-8 pubmed publisher
    ..In addition, to study wear resistance for industrial applications, a wear experiment was performed using an atomic force microscope (AFM). ..
  6. Bedics M, Mulhern K, Watson D, Detty M. Synthesis and photoelectrochemical performance of chalcogenopyrylium monomethine dyes bearing phosphonate/phosphonic acid substituents. J Org Chem. 2013;78:8885-91 pubmed publisher
    ..The dyes formed H-aggregates on TiO2, increasing the light-harvesting efficiency of the dyes. Shortcircuit photocurrent action spectra were acquired to evaluate the influence of dye structure on the photoelectrochemical performance. ..
  7. Graillot A, Bouyer D, Monge S, Robin J, Loison P, Faur C. Sorption properties of a new thermosensitive copolymeric sorbent bearing phosphonic acid moieties in multi-component solution of cationic species. J Hazard Mater. 2013;260:425-33 pubmed publisher
    ..The selectivity of the phosphonic acid moieties for aluminum cations was demonstrated, highlighting the interest of P(NnPAAm-stat-(h)MAPC1) for their use for the treatment of metallic pollution from wastewater. ..
  8. Li F, Fabbri J, Yurchenko R, Mileshkin A, Hohman J, Yan H, et al. Covalent attachment of diamondoid phosphonic acid dichlorides to tungsten oxide surfaces. Langmuir. 2013;29:9790-7 pubmed publisher
  9. Chen C, Fang J. Synthesis of oseltamivir and tamiphosphor from N-acetyl-D-glucosamine. Org Biomol Chem. 2013;11:7687-99 pubmed publisher
    ..The existing N-acetyl group was transformed into an azido group for the subsequent aziridination, followed by implantation of a 3-pentoxy group of the desired stereochemistry. ..
  10. Stempak D, Dallas S, Klein J, Bendayan R, Koren G, Baruchel S. Glutathione stability in whole blood: effects of various deproteinizing acids. Ther Drug Monit. 2001;23:542-9 pubmed
    ..Although immediate sample preparation is preferred, 15% PCA can maintain sample integrity for 4 weeks after storage at -80 degrees C. ..
  11. Han W, Zhao J, Wu Z, Zhang X, Yuan W. Asymmetric synthesis of ?-hydroxy-?-amino phosphonic acid derivatives via organocatalytic direct aldol reaction of ?-isothiocyanato phosphonates with aldehydes. J Org Chem. 2013;78:10541-7 pubmed publisher
    ..This work represents the first example of ?-isothiocyanato phosphonates serving as nucleophiles that are used in the catalytic asymmetric synthesis. ..
  12. Yin P, Chen L, Wang Z, Qu R, Liu X, Ren S. Production of biodiesel by esterification of oleic acid with ethanol over organophosphonic acid-functionalized silica. Bioresour Technol. 2012;110:258-63 pubmed publisher
    ..The research results show that SG-T-P is a potential catalyst for biodiesel production that can adsorb water from the reaction mixture at the same time. ..
  13. Liu M, Chen S, Zhao X, Ye Y, Li J, Zhu Q, et al. Biocompatible phosphonic acid-functionalized silica nanoparticles for sensitive detection of hypoxanthine in real samples. Talanta. 2013;117:536-42 pubmed publisher
    ..The assay results of hypoxanthine in fish samples were in a good agreement with the reference values. ..
  14. Wainwright P, Maddaford A, Zhang X, Billington H, Leese D, Glen R, et al. Synthesis and biological evaluation of acyclic phosphonic acid nucleoside derivatives. Nucleosides Nucleotides Nucleic Acids. 2013;32:477-92 pubmed publisher
    ..Practical synthetic routes are described for three targets, which were then tested against HIV, hepatitis C virus (HCV), and Dengue virus. ..
  15. Ullah S, Alsberg T, Vestergren R, Berger U. Determination of perfluoroalkyl carboxylic, sulfonic, and phosphonic acids in food. Anal Bioanal Chem. 2012;404:2193-201 pubmed publisher
    ..The method was successfully applied to a range of different food matrices including duplicate diet samples, vegetables, meat, and fish samples. ..
  16. Wagner N, Zimmermann P, Heisig P, Klitsche F, Maison W, Theato P. Investigation of Antifouling Properties of Surfaces Featuring Zwitterionic α-Aminophosphonic Acid Moieties. Macromol Biosci. 2015;15:1673-8 pubmed publisher
    ..After subsequent deprotection reaction of dialkyl phosphonates, the obtained zwitterionic surfaces were characterized by various techniques and we found excellent antifouling properties of the resulting films. ..
  17. Koshiishi I, Mamura Y, Liu J, Imanari T. Evaluation of an acidic deproteinization for the measurement of ascorbate and dehydroascorbate in plasma samples. Clin Chem. 1998;44:863-8 pubmed
    ..These results suggest that DHA detected in acidified plasma samples is an artifact resulting from AsA oxidation. ..
  18. Budd D, Qian Y. Development of lysophosphatidic acid pathway modulators as therapies for fibrosis. Future Med Chem. 2013;5:1935-52 pubmed publisher
    ..The therapeutic utility of LPA modulators for the treatment of fibrotic diseases will soon be revealed as clinical trials are already in progress in this area. ..
  19. Range K, McGrath M, Lopez X, York D. The structure and stability of biological metaphosphate, phosphate, and phosphorane compounds in the gas phase and in solution. J Am Chem Soc. 2004;126:1654-65 pubmed
    ..results presented here provide quantitative insight into RNA catalysis and serve as a first step toward the construction of a high-level quantum database for development of new semiempirical Hamiltonian models for biological reactions ..
  20. Ndase P, Celum C, Campbell J, Bukusi E, Kiarie J, Katabira E, et al. Successful discontinuation of the placebo arm and provision of an effective HIV prevention product after a positive interim efficacy result: the partners PrEP study experience. J Acquir Immune Defic Syndr. 2014;66:206-12 pubmed publisher
    ..The extent to which study sponsors can assure continued product access to research participants remains a subject of discussion for future HIV prevention clinical trials. ..
  21. Lv J, Jin Q, Sun H, Chi X, Hu X, Yan H, et al. Antiviral treatment alters the frequency of activating and inhibitory receptor-expressing natural killer cells in chronic hepatitis B virus infected patients. Mediators Inflamm. 2012;2012:804043 pubmed publisher
  22. Zhao Y, Zhang D, Xue C. A novel reagent, dialkylphosphite, for peptide synthesis. Int J Pept Protein Res. 1991;37:457-61 pubmed
    ..In addition, dialkyloxyphosphinyl group can be examined by 31P-NMR for peptide conformational analysis and inspection for the degree of racemization during the coupling reaction. ..
  23. Vettori C, Stotzky G, Yoder M, Gallori E. Interaction between bacteriophage PBS1 and clay minerals and transduction of Bacillus subtilis by clay-phage complexes. Environ Microbiol. 1999;1:347-55 pubmed
    ..Electron microscopic observations indicated that transduction by the clay-phage complexes was primarily the result of the phage detaching from the clays in the presence of host cells. ..
  24. Meng X, Kim S. Palladium(II)-catalyzed ortho-arylation of benzylic phosphonic monoesters using potassium aryltrifluoroborates. J Org Chem. 2013;78:11247-54 pubmed publisher
    ..A wide range of benzylic phosphonic monoesters underwent clean ortho-arylation in high yields, and excellent functional group tolerance was also observed. ..
  25. Amir A, Sayer A, Ezra A, Fischer B. Methylenediphosphonotetrathioate: synthesis, characterization, and chemical properties. Inorg Chem. 2013;52:3133-40 pubmed publisher
    ..The relative sensitivity of MDPT to oxidation may limit its use; however, the application of MDPT in acidic or basic media will increase its lifetime. ..
  26. Costa C, Casalta Lopes J, Andrade C, Moreira D, Oliveira A, Gonçalves A, et al. Farnesyltransferase inhibitors: molecular evidence of therapeutic efficacy in acute lymphoblastic leukemia through cyclin D1 inhibition. Anticancer Res. 2012;32:831-8 pubmed
    ..This study suggests that ?-HFPA blocks the cell cycle and induces cell death through apoptosis in CEM cells and may be a therapeutic approach in ALL. ..
  27. Ghidini A, Ander C, Winqvist A, Stromberg R. An RNA modification with remarkable resistance to RNase A. Chem Commun (Camb). 2013;49:9036-8 pubmed publisher
  28. Zhu D, Yao K, Bo J, Zhang H, Liu L, Dong X, et al. Hydrophilic/lipophilic N-methylene phosphonic chitosan as a promising non-viral vector for gene delivery. J Mater Sci Mater Med. 2010;21:223-9 pubmed publisher
    ..The expression of transgene mediated by NMPCS was much higher (more than 100-folds) than that mediated by CS, indicating that NMPCS was a more efficacious gene ferrying vector than CS. ..
  29. Grubač Z, Metikos Huković M, Babic R, Rončević I, Petravic M, Peter R. Functionalization of biodegradable magnesium alloy implants with alkylphosphonate self-assembled films. Mater Sci Eng C Mater Biol Appl. 2013;33:2152-8 pubmed publisher
    ..The existence of well organized and ordered self-assembled alkylphosphonate monolayers with good barrier protecting properties in a physiological solution is a key step in the development of biocompatible Mg-alloy implants. ..
  30. Margolis S, Paule R, Ziegler R. Ascorbic and dehydroascorbic acids measured in plasma preserved with dithiothreitol or metaphosphoric acid. Clin Chem. 1990;36:1750-5 pubmed
    ..The metaphosphoric-acid-treated samples were stable at -70 degrees C, but stability decreased with temperature over the range examined, 4-50 degrees C. ..
  31. Huang H, Chang W, Pai P, Romo A, Mansoorabadi S, Russell D, et al. Evidence for radical-mediated catalysis by HppE: a study using cyclopropyl and methylenecyclopropyl substrate analogues. J Am Chem Soc. 2012;134:16171-4 pubmed publisher
    ..Taken together, these findings provide, for the first time, experimental evidence for the involvement of a C2-centered radical intermediate with a lifetime on the order of nanoseconds in the HppE-catalyzed oxidation of (R)-HPP...
  32. Kim E, Hong J. Synthesis and Antiviral Activity Evaluation of 2',5',5'-Trifluoro-Apiosyl Nucleoside Phosphonic Acid Analogs. Nucleosides Nucleotides Nucleic Acids. 2016;35:130-46 pubmed publisher
    ..An antiviral evaluation of the synthesized compounds against various viruses such as HIV, HSV-1, HSV-2, and HCMV revealed that the pyrimidine analogues have significant anti-HCMV activity. ..
  33. Guo Y, Ferdani R, Anderson C. Preparation and biological evaluation of (64)Cu labeled Tyr(3)-octreotate using a phosphonic acid-based cross-bridged macrocyclic chelator. Bioconjug Chem. 2012;23:1470-7 pubmed publisher
  34. Pan C, Mi L, Bunchorntavakul C, Karsdon J, Huang W, Singhvi G, et al. Tenofovir disoproxil fumarate for prevention of vertical transmission of hepatitis B virus infection by highly viremic pregnant women: a case series. Dig Dis Sci. 2012;57:2423-9 pubmed publisher
    ..Use of TDF to prevent vertical transmission (VT) by such mothers has not been evaluated...
  35. Peyser J, Ferris J. The rates of hydrolysis of thymidyl-3',5'-thymidine-H-phosphonate: the possible role of nucleic acids linked by diesters of phosphorous acid in the origins of life. Orig Life Evol Biosph. 2001;31:363-80 pubmed
    ..These values are comparable with previous reports for the rates of hydrolysis of simple dialkyl esters of phosphorous acids. The Arrhenius activation energy for the base-catalyzed reaction is 20 kcal/mol...
  36. Aw M, Bariana M, Yu Y, Addai Mensah J, Losic D. Surface-functionalized diatom microcapsules for drug delivery of water-insoluble drugs. J Biomater Appl. 2013;28:163-74 pubmed publisher
  37. Georgantas D, Grigoropoulou H. Orthophosphate and metaphosphate ion removal from aqueous solution using alum and aluminum hydroxide. J Colloid Interface Sci. 2007;315:70-9 pubmed
    ..1-69.1) x 10(-3) (m(3)kg(-1))(1/N), 1/N: 0.14-0.19 for T=25-60 degrees C] and [ K(F)=(1.58-2.79) x 10(-3) (m(3)kg(-1))(1/N), 1/N: 2.17-2.47 for T=25-60 degrees C] for orthophosphate and metaphosphate, respectively...
  38. Xu D, Guo H. Ab initio QM/MM studies of the phosphoryl transfer reaction catalyzed by PEP mutase suggest a dissociative metaphosphate transition state. J Phys Chem B. 2008;112:4102-8 pubmed publisher
    ..It is also found that a substantial conformational change in the pyruvyl group is required for the interconversion...
  39. Jia C, Yang K, Liu C, Feng L, Xiao J, Zhou L, et al. Synthesis, characterization and activity of new phosphonate dipeptides as potential inhibitors of VanX. Bioorg Med Chem Lett. 2012;22:482-4 pubmed publisher
    ..This information will be helpful to guide the design and synthesis of the tightly-binding inhibitors for VanX...
  40. Corbett M, Uraguchi D, Ooi T, Johnson J. Base-catalyzed direct aldolization of ?-alkyl-?-hydroxy trialkyl phosphonoacetates. Angew Chem Int Ed Engl. 2012;51:4685-9 pubmed publisher
  41. Parker I, Price K, Singletary T, Srinivasan P, Smith J, Curtis K. A multiplex assay for detection of SHIV plasma and mucosal IgG and IgA. J Immunol Methods. 2017;450:34-40 pubmed publisher
    ..This SHIV assay elucidates IgG/IgA antibody kinetics in the plasma and vaginal mucosa and will be a valuable tool in vaccine and other biomedical intervention studies in the nonhuman primate model. ..
  42. Stojanovic M, Green E, Semova S, Nikic D, Landry D. Cross-reactive arrays based on three-way junctions. J Am Chem Soc. 2003;125:6085-9 pubmed
    ..The fingerprints can be used to characterize steroids in solution, including complex biologically important fluids. Arrays have the potential for clinical applications such as the detection of gross errors in steroidogenesis...
  43. Pappuru S, Chokkapu E, Chakraborty D, Ramkumar V. Group IV complexes containing the benzotriazole phenoxide ligand as catalysts for the ring-opening polymerization of lactides, epoxides and as precatalysts for the polymerization of ethylene. Dalton Trans. 2013;42:16412-27 pubmed publisher
    ..Compounds 1-12 were activated by methylaluminoxane (MAO) and show good activity for ethylene polymerization and produced high molecular weight polyethylene...
  44. Fisher J, Mobashery S. Recent advances in MMP inhibitor design. Cancer Metastasis Rev. 2006;25:115-36 pubmed
  45. Peters G. The effect of Asp54 phosphorylation on the energetics and dynamics in the response regulator protein Spo0F studied by molecular dynamics. Proteins. 2009;75:648-58 pubmed publisher
    ..However, phosphorylation does not affect the coordination number of the magnesium ion yielding, within the statistical uncertainties, the same free energy change...
  46. Zhong Z, Li G. [Determination of phosphate, pyrophosphate, metaphosphate and total phosphorus in seafoods by ion chromatography]. Se Pu. 2009;27:499-504 pubmed
    ..6% to 2.6%. The method was applied to the determination of anions in fish and shrimps with the recoveries of 81.8% - 100.0%. The method offered high selectivity, sensitivity, and gave a satisfactory results for real sample analysis...
  47. Yoshida T. Determination of reduced and oxidized glutathione in erythrocytes by high-performance liquid chromatography with ultraviolet absorbance detection. J Chromatogr B Biomed Appl. 1996;678:157-64 pubmed
    ..The stabilities of GSH and GSSG and of the derivatives were also examined. The present method appears to be satisfactory for determination of these physiological concentrations in erythrocytes...
  48. Esposito M, Dojcinovic I, Germon L, Lévy N, Curno R, Buchini S, et al. Safety and efficacy of a biomimetic monolayer of permanently bound multi-phosphonic acid molecules on dental implants: 1 year post-loading results from a pilot quadruple-blinded randomised controlled trial. Eur J Oral Implantol. 2013;6:227-36 pubmed
    ..SurfLink consists of a monolayer of permanently bound multi-phosphonic acid molecules, which mimics the surface of naturally occurring hydroxyapatite...
  49. Lanigan R. Final report on the safety assessment of Sodium Metaphosphate, Sodium Trimetaphosphate, and Sodium Hexametaphosphate. Int J Toxicol. 2001;20 Suppl 3:75-89 pubmed
  50. Maylin S, Boyd A, Martinot Peignoux M, Delaugerre C, Bagnard G, Lapalus M, et al. Quantification of hepatitis B e antigen between Elecsys HBeAg and Architect HBeAg assays among patients infected with hepatitis B virus. J Clin Virol. 2013;56:306-11 pubmed publisher
    ..No direct comparison has been made between assays that quantify HBeAg...
  51. Rejman D, Panova N, Klener P, Maswabi B, Pohl R, Rosenberg I. N-phosphonocarbonylpyrrolidine derivatives of guanine: a new class of bi-substrate inhibitors of human purine nucleoside phosphorylase. J Med Chem. 2012;55:1612-21 pubmed publisher
    ..The low (MESG)K(i) and (Pi)K(i) values of both compounds for PNP isolated from PBMCs suggest that these compounds could be bisubstrate inhibitors that occupy both the phosphate and nucleoside binding sites of the enzyme...
  52. Prado M, Archanjo B, Vasconcelos T, Ladeira L, Neves B. Characterizing inorganic crystals grown on organic self-assembled bilayers with scanning probe and electron microscopies. Microsc Res Tech. 2013;76:1278-83 pubmed publisher
    ..Compositional and structural characterization of these agglomerates (using TEM, EDS, and electron diffraction), revealed that they are indeed HAp, the main component of the inorganic bone matrix...
  53. Geary R, Yu R, Watanabe T, Henry S, Hardee G, Chappell A, et al. Pharmacokinetics of a tumor necrosis factor-alpha phosphorothioate 2'-O-(2-methoxyethyl) modified antisense oligonucleotide: comparison across species. Drug Metab Dispos. 2003;31:1419-28 pubmed
    ..This favorable pharmacokinetic profile for ISIS 104838 provides guidance for clinical development and appears to support infrequent and convenient dose administration...
  54. Baguley T, Xu H, Chatterjee M, Nairn A, Lombroso P, Ellman J. Substrate-based fragment identification for the development of selective, nonpeptidic inhibitors of striatal-enriched protein tyrosine phosphatase. J Med Chem. 2013;56:7636-50 pubmed publisher
    ..Significant levels of STEP inhibition in rat cortical neurons are also observed. ..
  55. de Macedo Ribeiro S, Renirie R, Wever R, Messerschmidt A. Crystal structure of a trapped phosphate intermediate in vanadium apochloroperoxidase catalyzing a dephosphorylation reaction. Biochemistry. 2008;47:929-34 pubmed publisher
    ..This is, to our knowledge, the first structural characterization of a real reaction intermediate of the inorganic phosphate group release in a dephosphorylation reaction...
  56. Dutta A, Patra A, Uyama H, Bhaumik A. Template-free synthesis of a porous organic-inorganic hybrid tin(IV) phosphonate and its high catalytic activity for esterification of free fatty acids. ACS Appl Mater Interfaces. 2013;5:9913-7 pubmed publisher
    ..The material exhibits remarkable catalytic activity for esterification of long chain fatty acids under mild reaction conditions at room temperature...
  57. Luisi G, Angelini G, Gasbarri C, Laghezza A, Agamennone M, Loiodice F, et al. Dual targeting of cancer-related human matrix metalloproteinases and carbonic anhydrases by chiral N-(biarylsulfonyl)-phosphonic acids. J Enzyme Inhib Med Chem. 2017;32:1260-1264 pubmed publisher
    ..We suggest here that the phosphonates have the potential as dual inhibitors of MMPs and CAs, both involved in tumor formation, invasion and metastasis...
  58. Gorriz J, Gutiérrez F, Trullàs J, Arazo P, Arribas J, Barril G, et al. [Executive summary of the recommendations on the evaluation and management of renal disease in human immunodeficiency virus-infected patients]. Enferm Infecc Microbiol Clin. 2014;32:583-97 pubmed publisher
    ..The indications for and evaluation and management of dialysis and renal transplantation are also addressed. ..
  59. Nyholm J, Gustafsson T, Ostin A. Structural determination of nerve agent markers using gas chromatography mass spectrometry after derivatization with 3-pyridyldiazomethane. J Mass Spectrom. 2013;48:813-22 pubmed publisher
    ..The suggested method will improve the unambiguous structural determination process for phosphonic acids...
  60. Graillot A, Bouyer D, Monge S, Robin J, Faur C. Removal of nickel ions from aqueous solution by low energy-consuming sorption process involving thermosensitive copolymers with phosphonic acid groups. J Hazard Mater. 2013;244-245:507-15 pubmed publisher
    ..The influence of the molar ratio of metal ions and phosphonate moieties was also studied and different sorption mechanisms were proposed...
  61. Djafer L, Ayral A, Boury B, Laine R. Surface modification of titania powder P25 with phosphate and phosphonic acids--effect on thermal stability and photocatalytic activity. J Colloid Interface Sci. 2013;393:335-9 pubmed publisher
    ..Thus, the objective of the work reported here is to focus on the role(s) that phosphorus plays only at TiO(2) crystallite surfaces. For comparison, other samples were treated with phosphoric acid...
  62. Lu C, Jia Y, Chen L, Ding Y, Yang J, Chen M, et al. Pharmacokinetics and food interaction of a novel prodrug of tenofovir, tenofovir dipivoxil fumarate, in healthy volunteers. J Clin Pharm Ther. 2013;38:136-40 pubmed publisher
    ..The aim of this study was to evaluate the pharmacokinetic properties and food interaction of tenofovir dipivoxil in healthy Chinese volunteers...
  63. Gargano A, Kohout M, Macikova P, Lämmerhofer M, Lindner W. Direct high-performance liquid chromatographic enantioseparation of free ?-, ?- and ?-aminophosphonic acids employing cinchona-based chiral zwitterionic ion exchangers. Anal Bioanal Chem. 2013;405:8027-38 pubmed publisher
  64. Frecska E, Móré C, Vargha A, Luna L. Enhancement of creative expression and entoptic phenomena as after-effects of repeated ayahuasca ceremonies. J Psychoactive Drugs. 2012;44:191-9 pubmed
    ..It also demonstrates an increased entoptic activity after repeated ayahuasca ingestion...
  65. Nandre K, Bhosale S, Rama Krishna K, Gupta A, Bhosale S. A phosphonic acid appended naphthalene diimide motif for self-assembly into tunable nanostructures through molecular recognition with arginine in water. Chem Commun (Camb). 2013;49:5444-6 pubmed publisher
  66. Unsworth W, Coulthard G, Kitsiou C, Taylor R. Direct imine acylation for molecular diversity in heterocyclic synthesis. J Org Chem. 2014;79:1368-76 pubmed
  67. Ghil L, Youn T, Park N, Rhee H. Proton conductive nano-channel membranes based on polyaniline with phosphonic acid moieties for low relative humidity. J Nanosci Nanotechnol. 2013;13:7912-5 pubmed
    ..Because the proton conductivity of Nafion decreases considerably at elevated temperature due to dehydration, our low cost membranes using phosphonic acid moiety may be expected to substitute sulfonic acid based-membranes such as Nafion...
  68. Clarion L, Jacquard C, Sainte Catherine O, Loiseau S, Filippini D, Hirlemann M, et al. Oxaphosphinanes: new therapeutic perspectives for glioblastoma. J Med Chem. 2012;55:2196-211 pubmed publisher
    ..1a is devoid of astrocyte toxicity. The original activity spectrum of 3.1a on the NCI cancer cell line panel allows the development of this family for use in association with existing drugs, opening new therapeutic perspectives...
  69. Bianchini G, Aschi M, Cavicchio G, Crucianelli M, Preziuso S, Gallina C, et al. Design, modelling, synthesis and biological evaluation of peptidomimetic phosphinates as inhibitors of matrix metalloproteinases MMP-2 and MMP-8. Bioorg Med Chem. 2005;13:4740-9 pubmed
    ..The differences in binding affinities for MMP-2 and MMP-8 of the three phosphinates have been rationalized by means of modelling studies and molecular dynamics simulations...
  70. Ikemura K, Endo T, Kadoma Y. A review of the developments of multi-purpose primers and adhesives comprising novel dithiooctanoate monomers and phosphonic acid monomers. Dent Mater J. 2012;31:1-25 pubmed
  71. Proniewicz E, Pięta E, Kudelski A, Piergies N, Skołuba D, Kim Y, et al. Vibrational and theoretical studies of the structure and adsorption mode of m-nitrophenyl ?-guanidinomethylphosphonic acid analogues on silver surfaces. J Phys Chem A. 2013;117:4963-72 pubmed publisher
    ..The geometry of these molecules on the SERS-active silver surfaces is deduced from the observed changes in both the intensity and width of the Raman bands in the spectra of the bound species relative to the free species...
  72. Colodrero R, Olivera Pastor P, Losilla E, Hernández Alonso D, Aranda M, Leon Reina L, et al. High proton conductivity in a flexible, cross-linked, ultramicroporous magnesium tetraphosphonate hybrid framework. Inorg Chem. 2012;51:7689-98 pubmed publisher
    ..High-pressure CO(2) adsorption data are also reported. Finally, impedance data indicates that 3 has high proton conductivity ? = 1.6 × 10(-3) S cm(-1) at T = 292 K at ~100% relative humidity with an activation energy of 0.31 eV...
  73. Allen M, Fuhrer W, Tuck B, Wade R, Wood J. Renin inhibitors. Synthesis of transition-state analogue inhibitors containing phosphorus acid derivatives at the scissile bond. J Med Chem. 1989;32:1652-61 pubmed
    ..0 x 10(-7) M for Z-Arg-Arg-Pro-Phe-His-(1b)-Ile-His-NH2. The shorter phosphonic acid sequence Z-Pro-Phe-His-(1d) retained biological activity with an IC50 = 6.4 x 10(-6) M...
  74. Zoutendijk R, Zaaijer H, de Vries Sluijs T, Reijnders J, Mulder J, Kroon F, et al. Hepatitis B surface antigen declines and clearance during long-term tenofovir therapy in patients coinfected with HBV and HIV. J Infect Dis. 2012;206:974-80 pubmed publisher
    ..Knowledge about the value of HBsAg levels in patients coinfected with HBV and human immunodeficiency virus (HIV) is lacking...
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    ..Based on our results, we are able to recommend that blood samples are immediately stabilized with dithioerythriol and protein precipitation conducted using trichloroacetic acid (TCA)...
  76. Algarra A, Fernández Trujillo M, Hernández Molina R, Basallote M. Kinetic, DFT and TD-DFT studies on the mechanism of stabilization of pyramidal H3PO3 at the [Mo3M'S4(H2O)10]4+ clusters (M' = Pd, Ni). Dalton Trans. 2011;40:8589-97 pubmed publisher
    ..Although it contains contributions from several transitions, the intense band observed for clusters containing coordinated pyr-H(3)PO(3) involves essentially ligand-to-metal charge-transfer (LMCT) transitions...
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    ..CdSe quantum dots and nanorods associate with these fibrils, leading to 'superhighways' that consist of alternating parallel lanes of conjugated polymer and CdSe...
  78. Kim A, Hong J, Oh C. Synthesis and anti-HCMV activity of novel cyclopropyl phosphonic acid nucleosides. Nucleosides Nucleotides Nucleic Acids. 2006;25:1399-406 pubmed
    ..In addition, the antiviral evaluations against various viruses were performed...
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    ..Advanced formulation may be investigated to develop these new anti-influenza agents for better therapeutic use...
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    ..Samples closely resembling human samples were also formed from the reaction of silicone oil with CaCO(3) in the presence of tetradecylphosphonic acid. Samples were characterized by SEM, XRD, and XPS and Raman spectroscopy...
  82. Wang G, Shen R, Xu Q, Goto M, Zhao Y, Han L. Stereospecific coupling of H-phosphinates and secondary phosphine oxides with amines and alcohols: a general method for the preparation of optically active organophosphorus acid derivatives. J Org Chem. 2010;75:3890-2 pubmed publisher
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    ..Treatment with phosphorous acid perturbed phosphorus distribution and lipid composition under low-phosphate conditions...
  84. Mulholland G, Jewett D, Toorongian S. Routine synthesis of N-[11C-methyl]scopolamine by phosphite mediated reductive methylation with [11C]formaldehyde. Int J Rad Appl Instrum A. 1988;39:373-9 pubmed
    ..Total synthesis time is less than 45 min. Decay corrected radiochemical yields from [11C]CO2 are presently 20-43%...
  85. Lu C, Jia Y, Yang J, Song Y, Liu W, Ding Y, et al. Relative bioavailability study of a novel prodrug of tenofovir, tenofovir dipivoxil fumarate, in healthy male fasted volunteers. Clin Drug Investig. 2012;32:333-8 pubmed publisher
    ..In addition, the bioavailability of tenofovir dipivoxil fumarate was evaluated in healthy male fasted subjects after a single comparatively equivalent dose...
  86. Bhattacharya S, Rao V, Sarkar S, Shunmugam R. Unusual emission from norbornene derived phosphonate molecule--a sensor for Fe(III) in aqueous environment. Nanoscale. 2012;4:6962-6 pubmed publisher
    ..Our hypothesis is further strengthened as there is no emission from NDPH1. The unusual fluorescence is utilized as a new fluorometric sensor that selectively detects Fe(III) ions...
  87. Faro L, de Almeida J, Cirne Santos C, Giongo V, Castello Branco L, Oliveira I, et al. Oxoquinoline acyclonucleoside phosphonate analogues as a new class of specific inhibitors of human immunodeficiency virus type 1. Bioorg Med Chem Lett. 2012;22:5055-8 pubmed publisher
    ..The most active compounds were the fluoro-substituted derivatives 3f and 3g, which presented excellent EC(50) values of 0.4±0.2 ?M (3f) and 0.2±0.005 ?M (3g) and selectivity index values (SI) of 6240 and 14675, respectively...
  88. Qi L, Fresnais J, Muller P, Theodoly O, Berret J, Chapel J. Interfacial activity of phosphonated-PEG functionalized cerium oxide nanoparticles. Langmuir. 2012;28:11448-56 pubmed publisher
    ..Mono- or multilayers can also be stably formed or transferred on solid surfaces. Our results are key features in the field of polymer surface modification, solid-stabilized emulsions (Pickering), or supracolloidal assemblies...
  89. Bhure R, Mahapatro A, Bonner C, Abdel Fattah T. In vitro stability study of organophosphonic self assembled monolayers (SAMs) on cobalt chromium (Co-Cr) alloy. Mater Sci Eng C Mater Biol Appl. 2013;33:2050-8 pubmed publisher
    ..Thus, ODPA SAMs were successfully coated on Cobalt Chromium (Co-Cr) alloy surface and were found to be stable and strongly bound after PBS exposure...
  90. Pawełczyk T, Olson M. Comparison of the kinetic properties of the pyruvate dehydrogenase complex from pig kidney cortex and medulla. Acta Biochim Pol. 1993;40:411-9 pubmed
    ..Based on the results presented in this report it is suggested that PDC in kidney medulla may be regulated not only by a phosphorylation/dephosphorylation system and end-product inhibition but also via changes in ionic strength...
  91. Wang Z, Cheng G, Liu Y, Zhang J, Sun D, Ni J. Novel core-shell cerium(IV)-immobilized magnetic polymeric microspheres for selective enrichment and rapid separation of phosphopeptides. J Colloid Interface Sci. 2014;417:217-26 pubmed publisher
    ..Thus the Fe3O4@SiO2@PVPA-Ce(IV) microspheres can benefit greatly the mass spectrometric qualitative analysis of phosphopeptides in phosphoproteome research. ..