tin polyphosphates

Summary

Summary: Poly or pyrophosphates of tin. In conjunction with radioactive technetium these compounds are used as bone-scanning agents and in scintigraphy to diagnose myocardial and cerebral infarction.

Top Publications

  1. Addy M, Greenman J, Renton Harper P, Newcombe R, Doherty F. Studies on stannous fluoride toothpaste and gel (2). Effects on salivary bacterial counts and plaque regrowth in vivo. J Clin Periodontol. 1997;24:86-91 pubmed
    ..This suggests the availability of stannous ions was important for the clinical effects. It is concluded that stannous ions can enhance the plaque inhibitory action of toothpaste via a persistent antimicrobial action...
  2. van der Meer N, Oomen M, Vonk Noordegraaf A, Pijpers R, Plaizier M, de Vries P. Does impedance cardiography reliably estimate left ventricular ejection fraction?. J Clin Monit. 1996;12:5-9 pubmed
    ..The ratio S/D might equal the LVEF (LVEFJud). A new LVEF calculation was introduced (LVEFimp) in this study based on the first derivative of the impedance signal, the thoracic impedance, and heart rate...
  3. Yu E, Sloggett C, Iwanochko R, Rakowski H, Siu S. Feasibility and accuracy of left ventricular volumes and ejection fraction determination by fundamental, tissue harmonic, and intravenous contrast imaging in difficult-to-image patients. J Am Soc Echocardiogr. 2000;13:216-24 pubmed
    ..For both ejection fraction and ventricular volumes, the observer variability was least for CON, intermediate with THI, and greatest for fundamental imaging...
  4. Knesewitsch P, Göldel N, Fritsch S, Moser E. [Evaluation of adriamycin cardiotoxicity using equilibrium radionuclide ventriculography. I. Results at rest]. Nuklearmedizin. 1987;26:206-11 pubmed
    ..At the beginning of ADM therapy 14% of the patients had subnormal R-gEF values. With increasing ADM doses pathologic findings increased to 86% in patients with ADM doses higher than 500 mg/m2...
  5. Schiff T, Hadley J, Petrone D, Petrone M, Chaknis P, DeVizio W, et al. Clinical efficacy of an optimized stannous fluoride dentifrice, Part 4: A 3-month calculus clinical study, northwest USA. Compend Contin Educ Dent. 1997;18 Spec No:21-3 pubmed
    ..The results of this study support the conclusion that the COSF dentifrice is efficacious for controlling the accumulation of supragingival calculus...
  6. Hashimoto T, Kambara H, Nohara R, Fudo T, Uozu K, Tamaki S, et al. [Evaluation of coronary reperfusion for acute myocardial infarction by emission CT using technetium-99m pyrophosphate]. J Cardiol. 1987;17:231-9 pubmed
    ..Using this method, Tc-US ranged from 2 to 39. The correlation of Tc-US with the peak serum creatine kinase level was significant (r = 0.91).(ABSTRACT TRUNCATED AT 250 WORDS)..
  7. Walton S. Early imaging of the infarct. Br J Hosp Med. 1987;38:326-32 pubmed
    ..Recent advances, such as the introduction of single-photon emission computed tomography and the introduction of novel radiopharmaceuticals, have suggested new clinical and research applications for them...
  8. Kronenberg M, Ettinger U, Wilson G, Schenk E, Cohen J. A comparison of radiotracer and biochemical methods for the quantitation of experimental myocardial infarct weight: in vitro relationships. J Nucl Med. 1979;20:224-31 pubmed
  9. Rantis P, Harford F, Wagner R, Henkin R. Technetium-labelled red blood cell scintigraphy: is it useful in acute lower gastrointestinal bleeding?. Int J Colorectal Dis. 1995;10:210-5 pubmed
    ..This may avoid the potential morbidity of arteriography in patients who are not actively bleeding...

More Information

Publications38

  1. Knesewitsch P, Göldel N, Fritsch S, Moser E. [Evaluation of adriamycin cardiotoxicity using equilibrium radionuclide ventriculography. II. Results during exercise]. Nuklearmedizin. 1987;26:212-9 pubmed
    ..Therefore, E-ERNV does not have a significantly higher sensitivity in the early detection of ADM-CMP than R-ERNV and is not required for the surveillance of patients under ADM therapy...
  2. Burke M, Gambogi R, Simone A, Williams M. The scientific rationale and development of an optimized stannous fluoride dentifrice, Part 1. Compend Contin Educ Dent. 1997;18 Spec No:2-9 pubmed
    ..Furthermore, the COSF dentifrice has been clinically shown not to cause the traditional stannous fluoride staining of dentition...
  3. Ballinger J, Pygas J, Gerson B, Gulenchyn K. Stabilization of stannous pyrophosphate kits with gentisic acid. Int J Rad Appl Instrum B. 1988;15:391-3 pubmed
    ..Gentisic acid is now used routinely in the Sn:PPi kit formulation in this institution...
  4. Hassan I, Mohammed M, Kouris K, Badrudoza M, Abdel Dayem H. Ventricular systolic and diastolic rate indices in patients with either normal or low resting left ventricular ejection fraction. Nucl Med Commun. 1989;10:669-78 pubmed
    ..46 +/- 0.27 EDV/s respectively). However, there was considerable overlap in values between groups. Therefore, we conclude that there is no single parameter more sensitive than LVEF in identifying IHD patients with normal LVEF at rest...
  5. Carson W, Tseng Y, Tseng C, Huang P, Wu T. Vectorcardiographic criteria for acute right ventricular infarction. Eur Heart J. 1988;9:955-61 pubmed
    ..Failure to recognize this electrical phenomenon may make the clinician inaccurate when judging the clinical course of acute right ventricular infarction or over-estimate the result of therapeutic intervention...
  6. Bjarnason I, Zanelli G, Prouse P, Smethurst P, Smith T, Levi S, et al. Blood and protein loss via small-intestinal inflammation induced by non-steroidal anti-inflammatory drugs. Lancet. 1987;2:711-4 pubmed
    ..These studies show that small intestinal inflammation caused by NSAIDs is associated with blood and protein loss, both of which may contribute to the general ill-health of rheumatic patients...
  7. Kawabe J, Higashiyama S, Torii K, Okamura T, Kotani J, Kawamura E, et al. Poor labeling of Tc-99m red blood cells in vivo in a radionuclide intestinal bleeding study of a patient who had recently undergone frequent blood transfusions. Clin Nucl Med. 2003;28:911-2 pubmed
    ..In radionuclide bleeding studies with patients with recent blood transfusion, Tc-99m HSA-D must be chosen instead of Tc-99m RBCs in vivo...
  8. Weismuller P, Henze E, Adam W, Roth J, Bitter F, Stauch M. Parametric imaging of experimentally simulated Wolff-Parkinson-White syndrome conduction abnormalities in dogs: a concise communication. Am J Physiol Imaging. 1986;1:208-13 pubmed
    ..Neither the antero- or posteroseptal nor the right ventricular premature contraction pattern could be exactly localized...
  9. Vucina J. [Radiochemical purity and stability of Tc-99m-pyrophosphate]. Med Pregl. 2000;53:502-5 pubmed
    ..In vitro stability of 99mTc-radiopharmaceuticals is an important parameter of quality. In the paper the shelf-life of the bone-seeking radiopharmaceutical 99mTc(Sn)-pyrophosphate was examined under different experimental conditions...
  10. Cheng M, Rao G, Zhou H, Xu J, Zhang F. Development of a new semi-quantitative non-invasive method for evaluating ventricular stroke work. Clin Physiol Funct Imaging. 2009;29:95-9 pubmed publisher
    ..In this paper, our aim is to develop a new semi-quantitative non-invasive method for evaluating ventricular SW...
  11. Naidu B, Pandey M, Sudarsan V, Ghatak J, Vatsa R. Investigations of Ce3+ co-doped SbPO4:Tb3+ nano-ribbons and nanoparticles by vibrational and photoluminescence spectroscopy. J Nanosci Nanotechnol. 2011;11:3180-90 pubmed
    ..These nanomaterials incorporated in silica matrix can have potential applications in bio-assays and bio-imaging...
  12. Wade W, Addy M, Hughes J, Milsom S, Doherty F. Studies on stannous fluoride toothpaste and gel (1). Antimicrobial properties and staining potential in vitro. J Clin Periodontol. 1997;24:81-5 pubmed
    ..In conclusion, the variation in antimicrobial activity and more particularly staining activity of the formulations suggest the products will vary in activity in vivo...
  13. Stallings L, Cheng K, Spicer K, Wiegner R, Humphries J. Ultratag RBC kit for combined cardiac first-pass and multigated acquisition studies. J Nucl Med Technol. 1997;25:44-8 pubmed
    ..5 ml) and a high labeling efficiency that can be used with a single-crystal camera to yield a quality study...
  14. Bosma M, Besho R, Walley D, Mankodi S, Petrone M, Chaknis P, et al. Clinical efficacy of an optimized stannous fluoride dentifrice, Part 5: A 3-month study of extrinsic tooth staining, northeast USA. Compend Contin Educ Dent. 1997;18 Spec No:24-7 pubmed
    ..243% sodium fluoride/silica dentifrice...
  15. Williams C, McBride S, Bolden T, Mostler K, Petrone D, Petrone M, et al. Clinical efficacy of an optimized stannous fluoride dentifrice, Part 3: A 6-month plaque/gingivitis clinical study, southeast USA. Compend Contin Educ Dent. 1997;18 Spec No:16-20 pubmed
    ..Thus, the results of this study reflect those found in the New Jersey study, i.e., supporting the conclusion that the COSF dentifrice is efficacious for the control of supragingival plaque and gingivitis...
  16. Jonski G, Young A, Waler S, Rolla G. Insoluble zinc, cupric and tin pyrophosphates inhibit the formation of volatile sulphur compounds. Eur J Oral Sci. 2004;112:429-32 pubmed
    ..Hence, the results support the experimental hypothesis. Sulphide ions are obviously very strong ligands for these metal ions...
  17. Goeree G, Coates G, Powles A, Basalygo M. Mechanisms of changes in nitrogen washout and lung volumes after saline infusion in humans. Am Rev Respir Dis. 1987;136:824-8 pubmed
    ..One is a simple displacement of air by increased intravascular volume producing the reduction in lung volumes. The second is an increase in small airways resistance that is mediated by vagal reflex and blocked with atropine...
  18. Sochor H, Schwaiger M, Schelbert H, Huang S, Ellison D, Hansen H, et al. Relationship between Tl-201, Tc-99m (Sn) pyrophosphate and F-18 2-deoxyglucose uptake in ischemically injured dog myocardium. Am Heart J. 1987;114:1066-77 pubmed
    ..Our results indicate that a dual tracer approach might best characterize the presence and extent of reversibly and of irreversibly injured tissue in a given myocardial region...
  19. Manyari D, Thompson C, Duff H, Knudtson M, Kloiber R, Smith E, et al. Usefulness of early positive technetium-99m stannous pyrophosphate scan in predicting reperfusion after thrombolytic therapy for acute myocardial infarction. Am J Cardiol. 1988;61:16-20 pubmed
    ..At this time, coronary cineangiography is the only reliable method to detect reperfusion promptly after thrombolytic therapy...
  20. Hougaard K, Kuur E. 99mTc-SN-pyrophosphate scintigraphy following traumatic posterior dislocation of the hip. Injury. 1988;19:389-92 pubmed
    ..It is concluded that 99mTc-SN-pyrophosphate scintigraphy 12 weeks after traumatic dislocation of the hip was unable to identify hips at risk of later development of avascular necrosis of the head of the femur...
  21. Hole T, Rokkones T. [Myocardial 99mTc-pyrophosphate scintigraphy in acute heart infarct]. Tidsskr Nor Laegeforen. 1990;110:596-7 pubmed
    ..55). We conclude that, in our hospital, 99mTc-pyrophosphate myocardial scintigraphy did not contribute valuable information to the routine diagnosis of myocardial infarction...
  22. Wallis J, Juni J, Wu L. Gated cardiac blood pool studies in atrial fibrillation: role of cycle length windowing. Eur J Nucl Med. 1991;18:23-7 pubmed
    ..abstract truncated at 250 words)..
  23. Cecconi M, Colonna P, Bettuzzi M, Manfrin M, Cesari G, Berrettini U, et al. [Competitive sports activity in subjects undergoing the surgical correction of an ostium-secundum type of interatrial defect: the experience of 9 cases]. G Ital Cardiol. 1991;21:175-88 pubmed
    ..A trivial tricuspid regurgitation was detected in 6 subjects; the peak velocity of the regurgitant jet was less than 2.1 m/sec.(ABSTRACT TRUNCATED AT 400 WORDS)..
  24. Yen C, Lanoie Y. Effect of stannous pyrophosphate red blood cell gastrointestinal bleeding scan on subsequent Meckel's scan. Clin Nucl Med. 1992;17:454-6 pubmed
    ..The Meckel's scan shows abnormal tracer distribution with absent gastric uptake, rendering the scan uninterpretable. In pediatric patients with gastrointestinal bleeding, a Meckel's scan should be done before labeled RBC imaging...
  25. Mankodi S, Petrone D, Battista G, Petrone M, Chaknis P, DeVizio W, et al. Clinical efficacy of an optimized stannous fluoride dentifrice, Part 2: A 6-month plaque/gingivitis clinical study, northeast USA. Compend Contin Educ Dent. 1997;18 Spec No:10-5 pubmed
    ..Thus, the results of this study support the conclusion that the COSF dentifrice is efficacious for the control of supragingival plaque and gingivitis...
  26. Schmelter R, Loo C. Localization and stability of technetium-99m-Sn-pyrophosphate in rat neutrophils. J Nucl Med. 1988;29:1406-10 pubmed
    ..We concluded that the variable labeling efficiency was due to the radiolabel's rather loose association with several cellular subfractions rather than specific binding to a unique substrate...
  27. Kroesbergen J, Roozen A, Gelsema W, de Ligny C. 99mTc bone scanning agents--IV. Chemical characterization of 99mTc(Sn)-pyrophosphate complexes. Int J Rad Appl Instrum B. 1988;15:209-14 pubmed
    ..At pH 7 one complex is found with the composition TcPyp2. Two complexes are found at pH 4: TcPyp and TcPyp2. Further, at pH 7 a polymeric technetium compound is found not containing tin or pyrophosphate...
  28. Bashore T, Grines C, Utlak D, Boudoulas H, Wooley C. Postural exercise abnormalities in symptomatic patients with mitral valve prolapse. J Am Coll Cardiol. 1988;11:499-507 pubmed
    ..Cardiac index measurements reflected the reduced left ventricular end-diastolic volume observed.(ABSTRACT TRUNCATED AT 250 WORDS)..
  29. Leslie W, Abrams D, Billinghurst M. Elution characteristics of 99Tcm-labelled erythrocytes in relation to scintigraphic detection of gastrointestinal bleeding. Nucl Med Commun. 1991;12:983-92 pubmed
    ..The possibility of gut and/or hepatobiliary secretion of this material needs further clarification before delayed positive studies can be relied upon to indicate gastrointestinal bleeding...