asbestos

Summary

Summary: Asbestos. Fibrous incombustible mineral composed of magnesium and calcium silicates with or without other elements. It is relatively inert chemically and used in thermal insulation and fireproofing. Inhalation of dust causes asbestosis and later lung and gastrointestinal neoplasms.

Top Publications

  1. Colangelo F, Cioffi R, Lavorgna M, Verdolotti L, De Stefano L. Treatment and recycling of asbestos-cement containing waste. J Hazard Mater. 2011;195:391-7 pubmed publisher
    The remediation of industrial buildings covered with asbestos-cement roofs is one of the most important issues in asbestos risk management...
  2. Ostroff R, Mehan M, Stewart A, Ayers D, Brody E, Williams S, et al. Early detection of malignant pleural mesothelioma in asbestos-exposed individuals with a noninvasive proteomics-based surveillance tool. PLoS ONE. 2012;7:e46091 pubmed publisher
    Malignant pleural mesothelioma (MM) is an aggressive, asbestos-related pulmonary cancer that is increasing in incidence...
  3. Hiraku Y, Kawanishi S, Ichinose T, Murata M. The role of iNOS-mediated DNA damage in infection- and asbestos-induced carcinogenesis. Ann N Y Acad Sci. 2010;1203:15-22 pubmed publisher
    ..and patients with various cancer-prone infectious and inflammatory diseases, caused by parasites, viruses, and asbestos exposure...
  4. Rice J. The global reorganization and revitalization of the asbestos industry, 1970-2007. Int J Health Serv. 2011;41:239-54 pubmed
    The intent of this essay is to highlight the global reorganization of the asbestos industry over the period 1970-2007...
  5. Mirabelli D, Cavone D, Merler E, Gennaro V, Romanelli A, Mensi C, et al. Non-occupational exposure to asbestos and malignant mesothelioma in the Italian National Registry of Mesotheliomas. Occup Environ Med. 2010;67:792-4 pubmed publisher
    Malignant mesotheliomas are strictly related to asbestos, but in a proportion of cases no exposure can be recalled. Published estimates of this proportion have important variations...
  6. Bitchatchi E, Kayser K, Perelman M, Richter E. Mesothelioma and asbestosis in a young woman following occupational asbestos exposure: Short latency and long survival: Case Report. Diagn Pathol. 2010;5:81 pubmed publisher
    ..with mesothelioma eight and one-half years following first exposure as a bystander to debris in a site in which asbestos-containing building materials were being dismantled and rebuilding work took place...
  7. Jasani B, Gibbs A. Mesothelioma not associated with asbestos exposure. Arch Pathol Lab Med. 2012;136:262-7 pubmed publisher
    Despite asbestos being identified as the single most important cause of malignant mesothelioma, the tumor is known to occur in only 10% to 20% of heavily exposed individuals...
  8. Robinson C, Woo S, Walsh A, Nowak A, Lake R. The antioxidants vitamins A and E and selenium do not reduce the incidence of asbestos-induced disease in a mouse model of mesothelioma. Nutr Cancer. 2012;64:315-22 pubmed publisher
    ..An effective cancer prevention strategy for the millions of people worldwide who have been exposed to asbestos could have enormous benefit...
  9. Alexander B, Raleigh K, Johnson J, Mandel J, Adgate J, Ramachandran G, et al. Radiographic evidence of nonoccupational asbestos exposure from processing Libby vermiculite in Minneapolis, Minnesota. Environ Health Perspect. 2012;120:44-9 pubmed publisher
    Community exposure to asbestos from contaminated vermiculite ore from Libby, Montana, occurred in many processing sites in the United States, including a densely populated urban residential neighborhood of Minneapolis, Minnesota...

More Information

Publications85

  1. Creaney J, Olsen N, Brims F, Dick I, Musk A, de Klerk N, et al. Serum mesothelin for early detection of asbestos-induced cancer malignant mesothelioma. Cancer Epidemiol Biomarkers Prev. 2010;19:2238-46 pubmed publisher
    Malignant mesothelioma is an aggressive, almost uniformly fatal tumor, primarily caused by exposure to asbestos. Since the recent discovery that serum mesothelin is a sensitive and highly specific biomarker for mesothelioma, one of the ..
  2. Andujar P, Pairon J, Renier A, Descatha A, Hysi I, Abd Alsamad I, et al. Differential mutation profiles and similar intronic TP53 polymorphisms in asbestos-related lung cancer and pleural mesothelioma. Mutagenesis. 2013;28:323-31 pubmed publisher
    Given the interest in defining biomarkers of asbestos exposure and to provide insights into asbestos-related and cell-specific mechanisms of neoplasia, the identification of gene alterations in asbestos-related cancers can help to a ..
  3. de Gennaro G, Dragonieri S, Longobardi F, Musti M, Stallone G, Trizio L, et al. Chemical characterization of exhaled breath to differentiate between patients with malignant plueral mesothelioma from subjects with similar professional asbestos exposure. Anal Bioanal Chem. 2010;398:3043-50 pubmed publisher
    Malignant pleural mesothelioma (MPM) is an aggressive tumour whose main aetiology is the long-term exposure to asbestos fibres...
  4. Liu G, Cheresh P, Kamp D. Molecular basis of asbestos-induced lung disease. Annu Rev Pathol. 2013;8:161-87 pubmed publisher
    b>Asbestos causes asbestosis and malignancies by molecular mechanisms that are not fully understood...
  5. Mossman B, Lippmann M, Hesterberg T, Kelsey K, Barchowsky A, Bonner J. Pulmonary endpoints (lung carcinomas and asbestosis) following inhalation exposure to asbestos. J Toxicol Environ Health B Crit Rev. 2011;14:76-121 pubmed publisher
    Lung carcinomas and pulmonary fibrosis (asbestosis) occur in asbestos workers...
  6. Santarelli L, Strafella E, Staffolani S, Amati M, Emanuelli M, Sartini D, et al. Association of MiR-126 with soluble mesothelin-related peptides, a marker for malignant mesothelioma. PLoS ONE. 2011;6:e18232 pubmed publisher
    ..Furthermore, the performance of the selected miR-126 as biomarker was evaluated in serum samples of asbestos-exposed subjects and MPM patients and compared with controls...
  7. Ameille J. [The different pleuro-pulmonary pathologies related to asbestos: definitions, epidemiology and evolution]. Rev Mal Respir. 2012;29:1035-46 pubmed publisher
    ..Fibrosis of the visceral pleura is much less common and it is not specifically related to asbestos. The incidence of asbestosis (pulmonary fibrosis induced by asbestos exposure) is diminishing in France...
  8. Shvedova A, Yanamala N, Kisin E, Tkach A, Murray A, Hubbs A, et al. Long-term effects of carbon containing engineered nanomaterials and asbestos in the lung: one year postexposure comparisons. Am J Physiol Lung Cell Mol Physiol. 2014;306:L170-82 pubmed publisher
    ..SWCNT) and carbon nanofibers (CNF), high length to width ratio, makes them similar to a hazardous agent, asbestos. Very limited data are available concerning long-term effects of pulmonary exposure to SWCNT or CNF...
  9. Frost G, Darnton A, Harding A. The effect of smoking on the risk of lung cancer mortality for asbestos workers in Great Britain (1971-2005). Ann Occup Hyg. 2011;55:239-47 pubmed publisher
    Workers in the asbestos industry tend to have high smoking rates compared to the general population...
  10. Myers R. Asbestos-related pleural disease. Curr Opin Pulm Med. 2012;18:377-81 pubmed publisher
    b>Asbestos exposure is the cause of significant pleural disease - both benign and malignant...
  11. Lacourt A, Rolland P, Gramond C, Astoul P, Chamming s S, Ducamp S, et al. Attributable risk in men in two French case-control studies on mesothelioma and asbestos. Eur J Epidemiol. 2010;25:799-806 pubmed publisher
    Pleural mesothelioma is a primary tumor of the pleura that is mainly due to asbestos exposure. To study the relationship between mesothelioma and occupational asbestos exposure in France, two case-control studies (A and B) were conducted...
  12. Lacourt A, Gramond C, Audignon S, Ducamp S, Fevotte J, Soit Ilg A, et al. Pleural mesothelioma and occupational coexposure to asbestos, mineral wool, and silica. Am J Respir Crit Care Med. 2013;187:977-82 pubmed publisher
    Occupational coexposure to asbestos and other fibers or particles could modify the carcinogenicity of asbestos with regard to pleural mesothelioma.
  13. Le G, Takahashi K, Park E, Delgermaa V, Oak C, Qureshi A, et al. Asbestos use and asbestos-related diseases in Asia: past, present and future. Respirology. 2011;16:767-75 pubmed publisher
    Although there are growing concerns about the global epidemic of asbestos-related diseases (ARD), the current status of asbestos use and ARD in Asia is elusive...
  14. Metintas S, Metintas M, Ak G, Kalyoncu C. Environmental asbestos exposure in rural Turkey and risk of lung cancer. Int J Environ Health Res. 2012;22:468-79 pubmed publisher
    The aim of this study was to determine the risk of lung cancer in a cohort of villagers with environmental asbestos exposure. The study was carried out as a field-based epidemiological study...
  15. Case B, Abraham J, Meeker G, Pooley F, Pinkerton K. Applying definitions of "asbestos" to environmental and "low-dose" exposure levels and health effects, particularly malignant mesothelioma. J Toxicol Environ Health B Crit Rev. 2011;14:3-39 pubmed publisher
    Although asbestos research has been ongoing for decades, this increased knowledge has not led to consensus in many areas of the field...
  16. Matsuzaki H, Maeda M, Lee S, Nishimura Y, Kumagai Takei N, Hayashi H, et al. Asbestos-induced cellular and molecular alteration of immunocompetent cells and their relationship with chronic inflammation and carcinogenesis. J Biomed Biotechnol. 2012;2012:492608 pubmed publisher
    b>Asbestos causes lung fibrosis known as asbestosis as well as cancers such as malignant mesothelioma and lung cancer. Asbestos is a mineral silicate containing iron, magnesium, and calcium with a core of SiO(2)...
  17. Pfau J, Li S, Holland S, Sentissi J. Alteration of fibroblast phenotype by asbestos-induced autoantibodies. J Immunotoxicol. 2011;8:159-69 pubmed publisher
    ..Because exposure to silicates such as silica and asbestos can lead to both autoantibodies and pulmonary/pleural fibrosis, these exposures provide an excellent tool for ..
  18. Kumagai Takei N, Maeda M, Chen Y, Matsuzaki H, Lee S, Nishimura Y, et al. Asbestos induces reduction of tumor immunity. Clin Dev Immunol. 2011;2011:481439 pubmed publisher
    b>Asbestos-related cancers such as malignant mesothelioma and lung cancer are an important issue in the world...
  19. Gemba K, Fujimoto N, Kato K, Aoe K, Takeshima Y, Inai K, et al. National survey of malignant mesothelioma and asbestos exposure in Japan. Cancer Sci. 2012;103:483-90 pubmed publisher
    ..of death due to MM between 2003 and 2008 to clarify the clinical features of MM, including its association with asbestos exposure (AE). Of all these cases, a clinical diagnosis of MM was confirmed for 929...
  20. Ameille J, Brochard P, Letourneux M, Paris C, Pairon J. Asbestos-related cancer risk in patients with asbestosis or pleural plaques. Rev Mal Respir. 2011;28:e11-7 pubmed publisher
    The relationships between benign asbestos-related diseases (asbestosis and pleural plaques) and thoracic cancers are still debated. The aim of this paper was to review the epidemiological data relevant to this issue.
  21. Schinwald A, Murphy F, Prina Mello A, Poland C, Byrne F, Movia D, et al. The threshold length for fiber-induced acute pleural inflammation: shedding light on the early events in asbestos-induced mesothelioma. Toxicol Sci. 2012;128:461-70 pubmed publisher
    Suspicion has been raised that high aspect ratio nanoparticles or nanofibers might possess asbestos-like pathogenicity. The pleural space is a specific target for disease in individuals exposed to asbestos and by implication of nanofibers...
  22. Camargo M, Stayner L, Straif K, Reina M, Al alem U, Demers P, et al. Occupational exposure to asbestos and ovarian cancer: a meta-analysis. Environ Health Perspect. 2011;119:1211-7 pubmed publisher
    ..Agency for Research on Cancer (IARC) concluded that there is sufficient evidence for a causal association between exposure to asbestos and ovarian cancer. We performed a meta-analysis to quantitatively evaluate this association.
  23. Wei S, Wang L, McHugh M, Han Y, Xiong M, Amos C, et al. Genome-wide gene-environment interaction analysis for asbestos exposure in lung cancer susceptibility. Carcinogenesis. 2012;33:1531-7 pubmed publisher
    b>Asbestos exposure is a known risk factor for lung cancer. Although recent genome-wide association studies (GWASs) have identified some novel loci for lung cancer risk, few addressed genome-wide gene-environment interactions...
  24. Wei B, Jia X, Ye B, Yu J, Zhang B, Zhang X, et al. Impacts of land use on spatial distribution of mortality rates of cancers caused by naturally occurring asbestos. J Expo Sci Environ Epidemiol. 2012;22:516-21 pubmed publisher
    ..laryngeal cancer, lung cancer, intestinal cancer, and mesothelioma were significantly associated with outcropped asbestos. Both the proportions of farmland and urban area were positively related to the mortality rates of nasopharyngeal ..
  25. Below J, Cox N, Fukagawa N, Hirvonen A, Testa J. Factors that impact susceptibility to fiber-induced health effects. J Toxicol Environ Health B Crit Rev. 2011;14:246-66 pubmed publisher
    b>Asbestos and related fibers are associated with a number of adverse health effects, including malignant mesothelioma (MM), an aggressive cancer that generally develops in the surface serosal cells of the pleural, pericardial, and ..
  26. Huang S, Jaurand M, Kamp D, Whysner J, Hei T. Role of mutagenicity in asbestos fiber-induced carcinogenicity and other diseases. J Toxicol Environ Health B Crit Rev. 2011;14:179-245 pubmed publisher
    The cellular and molecular mechanisms of how asbestos fibers induce cancers and other diseases are not well understood...
  27. Gualtieri A, Giacobbe C, Sardisco L, Saraceno M, Gualtieri M, Lusvardi G, et al. Recycling of the product of thermal inertization of cement-asbestos for various industrial applications. Waste Manag. 2011;31:91-100 pubmed publisher
    ..A potentially important secondary raw material is the product of the thermal transformation of cement-asbestos, produced by prolonged annealing at 1200-1300 °C. The product is chemically comparable to a Mg-rich clinker...
  28. Broaddus V, Everitt J, Black B, Kane A. Non-neoplastic and neoplastic pleural endpoints following fiber exposure. J Toxicol Environ Health B Crit Rev. 2011;14:153-78 pubmed publisher
    Exposure to asbestos fibers is associated with non-neoplastic pleural diseases including plaques, fibrosis, and benign effusions, as well as with diffuse malignant pleural mesothelioma...
  29. Aust A, Cook P, Dodson R. Morphological and chemical mechanisms of elongated mineral particle toxicities. J Toxicol Environ Health B Crit Rev. 2011;14:40-75 pubmed publisher
    ..of respirable elongated mineral particles (REMP) is based on studies involving the biological effects of asbestos fibers...
  30. Maeda M, Nishimura Y, Kumagai N, Hayashi H, Hatayama T, Katoh M, et al. Dysregulation of the immune system caused by silica and asbestos. J Immunotoxicol. 2010;7:268-78 pubmed publisher
    Silica and asbestos cause pneumoconioses known as silicosis and asbestosis, respectively, that are each characterized by progressive pulmonary fibrosis...
  31. Chapman E, Thomas P, Yates D. Breath analysis in asbestos-related disorders: a review of the literature and potential future applications. J Breath Res. 2010;4:034001 pubmed publisher
    b>Asbestos usage was very common worldwide in the last century and continues in several countries today...
  32. Dement J, Loomis D, Richardson D, Wolf S, Kuempel E. Estimates of historical exposures by phase contrast and transmission electron microscopy for pooled exposure--response analyses of North Carolina and South Carolina, USA asbestos textile cohorts. Occup Environ Med. 2011;68:593-8 pubmed publisher
    To develop pooled size-specific asbestos fiber exposure estimates for North Carolina and South Carolina asbestos textile plants.
  33. Turci F, Tomatis M, Lesci I, Roveri N, Fubini B. The iron-related molecular toxicity mechanism of synthetic asbestos nanofibres: a model study for high-aspect-ratio nanoparticles. Chemistry. 2011;17:350-8 pubmed publisher
    b>Asbestos shares with carbon nanotubes some morphological and physico-chemical features. An asbestos-like behaviour has been recently reported by some authors, though the mechanism of toxicity may be very different...
  34. Nishimura Y, Kumagai N, Maeda M, Hayashi H, Fukuoka K, Nakano T, et al. Suppressive effect of asbestos on cytotoxicity of human NK cells. Int J Immunopathol Pharmacol. 2011;24:5S-10S pubmed
    b>Asbestos, a naturally occurring fibrous mineral, causes malignant mesothelioma (MM)...
  35. Tomasetti M, Amati M, Nocchi L, Saccucci F, Strafella E, Staffolani S, et al. Asbestos exposure affects poly(ADP-ribose) polymerase-1 activity: role in asbestos-induced carcinogenesis. Mutagenesis. 2011;26:585-91 pubmed publisher
    b>Asbestos is known to induce malignant mesothelioma (MM) and other asbestos-related diseases. It is directly genotoxic by inducing DNA strand breaks and cytotoxic by promoting apoptosis in lung target cells...
  36. Neri M, Ugolini D, Boccia S, Canessa P, Cesario A, Leoncini G, et al. Chemoprevention of asbestos-linked cancers: a systematic review. Anticancer Res. 2012;32:1005-13 pubmed
    b>Asbestos has been used extensively and, in spite of many countries having banned most of its uses, professional, domestic and environmental exposure has not ceased worldwide...
  37. Harding A, Darnton A, Osman J. Cardiovascular disease mortality among British asbestos workers (1971-2005). Occup Environ Med. 2012;69:417-21 pubmed publisher
    b>Asbestos is an inflammatory agent, and there is evidence that inflammatory processes are involved in the development of cardiovascular disease. Whether asbestos is a risk factor for cardiovascular disease has not been established...
  38. Pascolo L, Gianoncelli A, Kaulich B, Rizzardi C, Schneider M, Bottin C, et al. Synchrotron soft X-ray imaging and fluorescence microscopy reveal novel features of asbestos body morphology and composition in human lung tissues. Part Fibre Toxicol. 2011;8:7 pubmed publisher
    Occupational or environmental exposure to asbestos fibres is associated with pleural and parenchymal lung diseases. A histopathologic hallmark of exposure to asbestos is the presence in lung parenchyma of the so-called asbestos bodies...
  39. Walker A, Maxim L, Utell M. Are airborne refractory ceramic fibers similar to asbestos in their carcinogenicity?. Inhal Toxicol. 2012;24:416-24 pubmed publisher
    Animal studies on refractory ceramic fiber (RCF) have led to the suggestion that RCF might resemble asbestos in carcinogenicity. Human data are available to test this hypothesis.
  40. Ordonez N. The use of immunohistochemistry in the diagnosis of composite and collision tumors: exemplified by pleural mesothelioma and carcinoid tumor of the lung. Appl Immunohistochem Mol Morphol. 2012;20:421-6 pubmed publisher
    ..a collision lymph node metastasis of a mesothelioma and a carcinoid tumor in a 73-year-old man with a history of asbestos exposure is reported...
  41. Paglietti F, Malinconico S, Di Molfetta V, Giangrasso M. Guidelines for asbestos remediation at Italian superfund sites. J Environ Sci Health C Environ Carcinog Ecotoxicol Rev. 2012;30:253-86 pubmed
    b>Asbestos is now banned in 52 countries...
  42. Maeda M, Nishimura Y, Hayashi H, Kumagai N, Chen Y, Murakami S, et al. Reduction of CXC chemokine receptor 3 in an in vitro model of continuous exposure to asbestos in a human T-cell line, MT-2. Am J Respir Cell Mol Biol. 2011;45:470-9 pubmed publisher
    ..also complications involving autoimmune diseases such as rheumatoid arthritis and systemic sclerosis, exposure to asbestos may affect the human immune system...
  43. Wang L, Stueckle T, Mishra A, Derk R, Meighan T, Castranova V, et al. Neoplastic-like transformation effect of single-walled and multi-walled carbon nanotubes compared to asbestos on human lung small airway epithelial cells. Nanotoxicology. 2014;8:485-507 pubmed publisher
    ..With similar fibrous morphology and mode of exposure to asbestos, a known human carcinogen, growing concern has arisen for elevated risk of CNT-induced lung carcinogenesis; ..
  44. Chew S, Okazaki Y, Nagai H, Misawa N, Akatsuka S, Yamashita K, et al. Cancer-promoting role of adipocytes in asbestos-induced mesothelial carcinogenesis through dysregulated adipocytokine production. Carcinogenesis. 2014;35:164-72 pubmed publisher
    ..Both macrophages and mesothelial cells play crucial roles in the inflammatory response caused by asbestos exposure...
  45. Nymark P, Guled M, Borze I, Faisal A, Lahti L, Salmenkivi K, et al. Integrative analysis of microRNA, mRNA and aCGH data reveals asbestos- and histology-related changes in lung cancer. Genes Chromosomes Cancer. 2011;50:585-97 pubmed publisher
    Lung cancer has the highest mortality rate of all of the cancers in the world and asbestos-related lung cancer is one of the leading occupational cancers...
  46. Gómez M, Castañeda R, López V, Vidal M, Villanueva V, Espinosa M. Evaluation of the national health surveillance program of workers previously exposed to asbestos in Spain (2008). Gac Sanit. 2012;26:45-50 pubmed publisher
    Although asbestos was banned in Spain in 2001, monitoring the health of previously-exposed workers is required...
  47. Park E, Takahashi K, Hoshuyama T, Cheng T, Delgermaa V, Le G, et al. Global magnitude of reported and unreported mesothelioma. Environ Health Perspect. 2011;119:514-8 pubmed publisher
    Little is known about the global magnitude of mesothelioma. In particular, many developing countries, including some with extensive historical use of asbestos, do not report mesothelioma.
  48. Carbone M, Yang H. Molecular pathways: targeting mechanisms of asbestos and erionite carcinogenesis in mesothelioma. Clin Cancer Res. 2012;18:598-604 pubmed publisher
    Malignant mesothelioma is an aggressive malignancy related to asbestos and erionite exposure. AP-1 transcriptional activity and the NF-?B signaling pathway have been linked to mesothelial cell transformation and tumor progression...
  49. Clin B, Morlais F, Launoy G, Guizard A, Dubois B, Bouvier V, et al. Cancer incidence within a cohort occupationally exposed to asbestos: a study of dose--response relationships. Occup Environ Med. 2011;68:832-6 pubmed publisher
    The aim of our study was to analyse the dose-response relationship between occupational asbestos exposure and risk of cancer.
  50. Chow M, Tschopp J, Möller A, Smyth M. NLRP3 promotes inflammation-induced skin cancer but is dispensable for asbestos-induced mesothelioma. Immunol Cell Biol. 2012;90:983-6 pubmed publisher
    b>Asbestos exposure can result in serious and frequently lethal diseases, including malignant mesothelioma...
  51. Harding A, Darnton A. Asbestosis and mesothelioma among British asbestos workers (1971-2005). Am J Ind Med. 2010;53:1070-80 pubmed publisher
    ..The aims of this study were to estimate the true frequency of asbestosis and mesothelioma among asbestos workers in Great Britain (GB), and to identify factors associated with the risk of death with these diseases.
  52. Moon E, Son M, Jin Y, Park S, Lee W. Variations of lung cancer risk from asbestos exposure: impact on estimation of population attributable fraction. Ind Health. 2013;51:128-33 pubmed
    ..of differing lung cancer risks in study populations on estimating population attributable fraction (PAF) from asbestos exposure...
  53. Stayner L, Welch L, Lemen R. The worldwide pandemic of asbestos-related diseases. Annu Rev Public Health. 2013;34:205-16 pubmed publisher
    b>Asbestos-related diseases are still a major public health problem. The World Health Organization (WHO) has estimated that 107,000 people worldwide die each year from mesothelioma, lung cancer, and asbestosis...
  54. Stella G. Carbon nanotubes and pleural damage: perspectives of nanosafety in the light of asbestos experience. Biointerphases. 2011;6:P1-17 pubmed publisher
    ..Burgeoning evidence demonstrates that carbon nanotubes and asbestos share comparable physical properties...
  55. Adib G, Labrèche F, De Guire L, Dion C, Dufresne A. Short, fine and WHO asbestos fibers in the lungs of quebec workers with an asbestos-related disease. Am J Ind Med. 2013;56:1001-14 pubmed publisher
    The possible role of short asbestos fibers in the development of asbestos-related diseases and availability of lung fiber burden data prompted this study on the relationships between fiber characteristics and asbestos-related diseases ..
  56. Linton A, Vardy J, Clarke S, van Zandwijk N. The ticking time-bomb of asbestos: its insidious role in the development of malignant mesothelioma. Crit Rev Oncol Hematol. 2012;84:200-12 pubmed publisher
    The relationship between asbestos exposure and malignant mesothelioma (MM) has been well established...
  57. Naimi A, Cole S, Hudgens M, Brookhart M, Richardson D. Assessing the component associations of the healthy worker survivor bias: occupational asbestos exposure and lung cancer mortality. Ann Epidemiol. 2013;23:334-41 pubmed publisher
    ..Together, these associations result in time-varying confounding affected by prior exposure. We illustrate how these associations can be assessed using standard regression methods...
  58. Osmond McLeod M, Poland C, Murphy F, Waddington L, Morris H, Hawkins S, et al. Durability and inflammogenic impact of carbon nanotubes compared with asbestos fibres. Part Fibre Toxicol. 2011;8:15 pubmed publisher
    ..suggested that carbon nanotubes might conform to the fibre pathogenicity paradigm that explains the toxicities of asbestos and other fibres on a continuum based on length, aspect ratio and biopersistence...
  59. Peters S, Vermeulen R, Cassidy A, Mannetje A, van Tongeren M, Boffetta P, et al. Comparison of exposure assessment methods for occupational carcinogens in a multi-centre lung cancer case-control study. Occup Environ Med. 2011;68:148-53 pubmed publisher
    ..Different methods have been developed, including case-by-case expert assessment and job-exposure matrices (JEM). The present analyses compare exposure prevalence and risk estimates derived by different exposure assessment methods...
  60. Tomioka K, Natori Y, Kumagai S, Kurumatani N. An updated historical cohort mortality study of workers exposed to asbestos in a refitting shipyard, 1947-2007. Int Arch Occup Environ Health. 2011;84:959-67 pubmed publisher
    To evaluate the long-term health effects of occupational asbestos exposure, an updated historical cohort mortality study of workers at a refitting shipyard was undertaken.
  61. Altomare D, Menges C, Xu J, Pei J, Zhang L, Tadevosyan A, et al. Losses of both products of the Cdkn2a/Arf locus contribute to asbestos-induced mesothelioma development and cooperate to accelerate tumorigenesis. PLoS ONE. 2011;6:e18828 pubmed publisher
    ..To further test this notion, we exposed Ink4a(+/-) and Arf(+/-) mice to asbestos, the major cause of MM...
  62. Gramond C, Rolland P, Lacourt A, Ducamp S, Chamming s S, Créau Y, et al. Choice of rating method for assessing occupational asbestos exposure: study for compensation purposes in France. Am J Ind Med. 2012;55:440-9 pubmed publisher
    ..The aim of this study was to define the most suitable rating method for assessing occupational asbestos exposure in order to assess medico-social care.
  63. Mensi C, Giacomini S, Sieno C, Consonni D, Riboldi L. Pericardial mesothelioma and asbestos exposure. Int J Hyg Environ Health. 2011;214:276-9 pubmed publisher
    Pericardial mesothelioma (PM) accounts for 0.7% of all malignant mesotheliomas. Although asbestos exposure is a recognized etiological factor for pleural and peritoneal mesotheliomas, its role in the development of PM is controversial...
  64. Marioryad H, Kakooei H, Shahtaheri S, Yunesian M, Azam K. Assessment of airborne asbestos exposure at an asbestos cement sheet and pipe factory in Iran. Regul Toxicol Pharmacol. 2011;60:200-5 pubmed publisher
    Iran imports nearly 55,000 metric tons of asbestos per year, and asbestos cement (AC) plants contribute nearly 94% of the total national usage...
  65. Fazzo L, De Santis M, Minelli G, Bruno C, Zona A, Marinaccio A, et al. Pleural mesothelioma mortality and asbestos exposure mapping in Italy. Am J Ind Med. 2012;55:11-24 pubmed publisher
    An epidemic of asbestos-related diseases is ongoing worldwide. Mortality from malignant pleural neoplasms in Italy was analyzed, to estimate the health impact of asbestos at national and local level.
  66. Huang S, Partridge M, Ghandhi S, Davidson M, Amundson S, Hei T. Mitochondria-derived reactive intermediate species mediate asbestos-induced genotoxicity and oxidative stress-responsive signaling pathways. Environ Health Perspect. 2012;120:840-7 pubmed publisher
    The incidence of asbestos-induced human cancers is increasing worldwide, and considerable evidence suggests that reactive oxygen species (ROS) are important mediators of these diseases...
  67. Jamrozik E, de Klerk N, Musk A. Asbestos-related disease. Intern Med J. 2011;41:372-80 pubmed publisher
    Inhalation of airborne asbestos fibres causes several diseases. These include asbestosis, lung cancer, malignant mesothelioma as well as pleural effusion, discrete (plaques) or diffuse benign pleural fibrosis and rolled atelectasis...
  68. Adgate J, Cho S, Alexander B, Ramachandran G, Raleigh K, Johnson J, et al. Modeling community asbestos exposure near a vermiculite processing facility: Impact of human activities on cumulative exposure. J Expo Sci Environ Epidemiol. 2011;21:529-35 pubmed publisher
    ..The objective of this analysis was to estimate potential cumulative asbestos exposure for all non-occupationally exposed members of this community...
  69. Paget Bailly S, Cyr D, Luce D. Occupational exposures to asbestos, polycyclic aromatic hydrocarbons and solvents, and cancers of the oral cavity and pharynx: a quantitative literature review. Int Arch Occup Environ Health. 2012;85:341-51 pubmed publisher
    ..This quantitative review summarizes epidemiological findings on exposure to asbestos, polycyclic aromatic hydrocarbons and solvents, and cancers of the oral cavity and pharynx.
  70. Gwinn M, DeVoney D, Jarabek A, Sonawane B, Wheeler J, Weissman D, et al. Meeting report: mode(s) of action of asbestos and related mineral fibers. Environ Health Perspect. 2011;119:1806-10 pubmed publisher
    Although asbestos in general is well known to cause a range of neoplastic and non-neoplastic human health effects, not all asbestos fiber types have the same disease-causing potential, and the mode of action (MOA) of specific types of ..
  71. Comar M, Zanotta N, Pesel G, Visconti P, Maestri I, Rinaldi R, et al. Asbestos and SV40 in malignant pleural mesothelioma from a hyperendemic area of north-eastern Italy. Tumori. 2012;98:210-4 pubmed publisher
    Malignant mesothelioma is a fatal cancer of increasing incidence in north-eastern Italy. Together with asbestos, the polyomavirus SV40 was hypothesized to contribute to the onset of malignant mesothelioma...
  72. Cristaudo A, Foddis R, Bonotti A, Simonini S, Vivaldi A, Guglielmi G, et al. Comparison between plasma and serum osteopontin levels: usefulness in diagnosis of epithelial malignant pleural mesothelioma. Int J Biol Markers. 2010;25:164-70 pubmed
    ..OPN, to compare serum and plasma OPN in the same population, and to assess whether OPN levels can aid in the diagnostic distinction of patients with MPM versus benign respiratory disease (BRD) and healthy subjects exposed to asbestos.
  73. Betti M, Ferrante D, Padoan M, Guarrera S, Giordano M, Aspesi A, et al. XRCC1 and ERCC1 variants modify malignant mesothelioma risk: a case-control study. Mutat Res. 2011;708:11-20 pubmed publisher
    Malignant pleural mesothelioma (MPM) is a rare aggressive tumor associated with asbestos exposure...
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    ..exposure during production and their fibrous shape raises the possibility that they may have effects like asbestos, which caused a worldwide pandemic of disease in the20th century that continues into present...
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    The model of asbestos-related mesothelioma implies that the time since first exposure (latency) is the key determinant of subsequent risk. The role of recent exposure or stopping asbestos exposure, if any, is, however, open to discussion...
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    ..to minerals is an important factor in the development of malignant mesothelioma (MM), especially the mineral asbestos, which has a well-documented role in MM, and more recently, the mineral erionite has been proven to be a strong ..