cobalt radioisotopes

Summary

Summary: Unstable isotopes of cobalt that decay or disintegrate emitting radiation. Co atoms with atomic weights of 54-64, except 59, are radioactive cobalt isotopes.

Top Publications

  1. Adams E, Warrington A. A comparison between cobalt and linear accelerator-based treatment plans for conformal and intensity-modulated radiotherapy. Br J Radiol. 2008;81:304-10 pubmed publisher
    ..If cobalt units were to have such features incorporated into them, they could offer considerable benefits to the radiotherapy community...
  2. Liu Q, Jiang B, Jiang L, Wu Y, Wang X, Zhao F, et al. Clinical report of three cases of acute radiation sickness from a (60)Co radiation accident in Henan Province in China. J Radiat Res. 2008;49:63-9 pubmed
    ..The experience obtained from the medical management of these patients is valuable for the treatment of such patients in the future...
  3. Alam M, Miah M, Chowdhury M, Kamal M, Ghose S, Rahman R. Attenuation coefficients of soils and some building materials of Bangladesh in the energy range 276-1332 keV. Appl Radiat Isot. 2001;54:973-6 pubmed
    ..The measured mass attenuation coefficient values were compared with measurements made in other countries for similar kinds of materials. The values are in good agreement with each other in most cases...
  4. Broome E, Brown D, Mitchel R. Dose responses for adaption to low doses of (60)Co gamma rays and (3)H beta particles in normal human fibroblasts. Radiat Res. 2002;158:181-6 pubmed
    ..The results also show that the RBE for low doses of tritium beta-particle radiation is 1, using adaption as the end point...
  5. Garaj Vrhovac V, Kopjar N, Razem D, Vekić B, Miljanic S, Ranogajec Komor M. Application of the alkaline comet assay in biodosimetry: assessment of in vivo DNA damage in human peripheral leukocytes after a gamma radiation incident. Radiat Prot Dosimetry. 2002;98:407-16 pubmed
    ..The results obtained indicate that the alkaline comet assay is a rapid and sensitive microdosimetric technique and is suitable for in vivo human biomonitoring, especially in cases of incidental exposure to ionising radiation...
  6. Ballester F, Granero D, Perez Calatayud J, Casal E, Agramunt S, Cases R. Monte Carlo dosimetric study of the BEBIG Co-60 HDR source. Phys Med Biol. 2005;50:N309-16 pubmed
    ..These dosimetric datasets can be used as input data and to validate the treatment planning system calculations...
  7. Johansson S, Svensson H, Denekamp J. Timescale of evolution of late radiation injury after postoperative radiotherapy of breast cancer patients. Int J Radiat Oncol Biol Phys. 2000;48:745-50 pubmed
  8. Yang Y, Cao M, Sheng K, Gao Y, Chen A, Kamrava M, et al. Longitudinal diffusion MRI for treatment response assessment: Preliminary experience using an MRI-guided tri-cobalt 60 radiotherapy system. Med Phys. 2016;43:1369-73 pubmed publisher
    ..To demonstrate the preliminary feasibility of a longitudinal diffusion magnetic resonance imaging (MRI) strategy for assessing patient response to radiotherapy at 0.35 T using an MRI-guided radiotherapy system (ViewRay)...
  9. Farcy E, Voiseux C, Robbes I, Lebel J, Fievet B. Effect of ionizing radiation on the transcription levels of cell stress marker genes in the Pacific oyster Crassostrea gigas. Radiat Res. 2011;176:38-48 pubmed
    ..The possible role of these stress genes in the resistance of oysters to ionizing radiation is discussed...

More Information

Publications62

  1. Benny P, Shah M, Sabharwal S. Evaluation of the efficiency and throughput of a gamma irradiator treating municipal sewage sludge. Appl Radiat Isot. 2011;69:604-6 pubmed publisher
    ..Also, the open-loop system and the closed-loop system are compared in terms of the effective dose rate...
  2. Moussous O, Medjadj T, Benguerba M. FBX aqueous chemical dosimeter for measurement of dosimetric parameters. Appl Radiat Isot. 2011;69:399-402 pubmed publisher
    ..We thus believe that the tissue equivalent FBX dosimetry system can measure the dosimetric parameters for (60)Co with reasonable accuracy...
  3. Yan S, Liu L, Liu Z, Zeng M, Song L, Xia Y. [Expression and clinical significance of DNA-PKcs in nasopharyngeal carcinoma]. Ai Zheng. 2008;27:979-83 pubmed
    ..This study was to investigate the expression of DNA-PKcs in nasopharyngeal carcinoma (NPC), and analyze its correlation to the clinicopathologic features and prognosis of NPC...
  4. Jasiulionis R, Rozkov A. The solubility of the aerosol, 137Cs and 60Co carrier, in the Ignalina Nuclear Power Plant region. Appl Radiat Isot. 2008;66:1992-8 pubmed publisher
    ..The radionuclide activity concentration distribution in the ground-level air is calculated in respect of the insolubility in water of (60)Co attached to aerosol particles and compared with experimental data...
  5. Nunn A, Davis S, Micka J, DeWerd L. LiF:Mg,Ti TLD response as a function of photon energy for moderately filtered x-ray spectra in the range of 20-250 kVp relative to 60Co. Med Phys. 2008;35:1859-69 pubmed
    ..Radiat. Prot. Dosim. 106, 33-43 (2003)]. This is likely due to complications in the solid state physics of the thermoluminescence process that are not incorporated into the simulation...
  6. Parra N, Ege C, Ledney G. Retrospective analyses of serum lipids and lipoproteins and severity of disease in 60Co-irradiated Sus scrofa domestica and Macaca mulatta. Comp Med. 2007;57:298-304 pubmed
    ..Our data indicate that HDL is a reliable marker for severity of disease in these 2 preclinical models of irradiation-induced sepsis...
  7. Shen X, Wang Z, Yu X. [Mutagenic effects of gamma-rays on Coix lacryma-jobi var. ma-yuen]. Zhongguo Zhong Yao Za Zhi. 2007;32:1016-8 pubmed
    ..To study the mutagenic effect of gamma-rays on Coix lacryma-jobi var. ma-yuen...
  8. Murataka A, Endo S, Kojima Y, Shizuma K. Dose rate estimation around a 60Co gamma-ray irradiation source by means of 115mIn photoactivation. J Radiat Res. 2010;51:197-203 pubmed
    ..It is demonstrated that (115m)In photoactivation is a convenient method to estimate the dose rate distribution around a (60)Co source...
  9. Massillon Jl G, Minniti R, Soares C, Maryanski M, Robertson S. Characteristics of a new polymer gel for high-dose gradient dosimetry using a micro optical CT scanner. Appl Radiat Isot. 2010;68:144-54 pubmed publisher
    ..The response of the gel was found to have no dose rate dependence for dose rates ranging from 3.7 to 15mGy/s. Within the measurement uncertainty, the gel response is more sensitive for beta particles than high energy photons...
  10. Otto T, Gindraux L, Strasser M. The thermoluminescence efficiency of Li2B4O7:Cu and of CaSO4:Tm for photons. Radiat Prot Dosimetry. 2011;144:234-8 pubmed publisher
    ..The results of the study are in agreement with predictions from track structure theory and microdosimetry, relating an enhanced light yield at low X-ray energies to supralinear behaviour of the TL phosphor...
  11. Garnica Garza H. Monte Carlo-derived TLD cross-calibration factors for treatment verification and measurement of skin dose in accelerated partial breast irradiation. Phys Med Biol. 2009;54:1621-31 pubmed publisher
    ..Such factors may also prove to be useful for those standardized laboratories that provide postal dosimetry services...
  12. Wang L, Rogers D. Calculation of the replacement correction factors for ion chambers in megavoltage beams by Monte Carlo simulation. Med Phys. 2008;35:1747-55 pubmed
    ..The nonunity values of P(repl) for plane-parallel chambers in lower energy electron beams imply a variety of values used in dosimetry protocols must be reassessed...
  13. Enger S, Lundqvist H, D Amours M, Beaulieu L. Exploring (57)Co as a new isotope for brachytherapy applications. Med Phys. 2012;39:2342-5 pubmed publisher
    ..57)Co decays by electron capture to the stable (57)Fe with emission of 136 and 122 keV photons...
  14. Kumarathasan P, Vincent R, Blais E, Saravanamuthu A, Gupta P, Wyatt H, et al. Cardiovascular changes in atherosclerotic ApoE-deficient mice exposed to Co60 (?) radiation. PLoS ONE. 2013;8:e65486 pubmed publisher
  15. Ossetrova N, Condliffe D, Ney P, Krasnopolsky K, Hieber K, Rahman A, et al. Early-response biomarkers for assessment of radiation exposure in a mouse total-body irradiation model. Health Phys. 2014;106:772-86 pubmed publisher
  16. Annalakshmi O, Jose M, Madhusoodanan U. Synthesis and characterisation of BaSo4:Eu thermoluminescence phosphor. Radiat Prot Dosimetry. 2012;150:127-33 pubmed publisher
  17. Simon S, Desmedt F, Vanderlinden B, Gevaert T, Vandekerkhove C, Grell A, et al. Medical physics principles of radiosurgery. Prog Neurol Surg. 2007;20:43-9 pubmed
    ..Conformity and selectivity should be evaluated for each treatment with the help of some specific indices, i.e. target volume ratio and normal volume ratio based on the dose-volume histograms...
  18. Hoile R, Banos C, Colella M, Roux C. Bioterrorism: the effects of biological decontamination on the recovery of electronic evidence. Forensic Sci Int. 2011;209:143-8 pubmed publisher
    ..Gamma irradiation proved damaging to electronic circuitry at levels required to render the items safe. The implications to computer intelligence and forensics will be discussed based on the outcomes of these findings...
  19. Hu J, Wang J. [Degradation of 3-chlorophenol in aqueous solution by combined process of gamma-radiation and H2O2]. Huan Jing Ke Xue. 2009;30:2936-9 pubmed
    ..The rate constant of 3-CP degradation for gamma-radiation and gamma-radiation/hydrogen peroxide combined process was 0.279 h(-1) and 0.542 h(-1), respectively...
  20. Cengel K, Diffenderfer E, Avery S, Kennedy A, McDonough J. Using electron beam radiation to simulate the dose distribution for whole body solar particle event proton exposure. Radiat Environ Biophys. 2010;49:715-21 pubmed publisher
    ..These studies will help to better define the topography of the time-dose-fractionation versus biological response landscape for astronaut exposure to an SPE...
  21. Singh I, Ravindran B, Ayyangar K. Adaptation of telecobalt unit for stereotactic irradiation. Med Dosim. 2007;32:52-8 pubmed
  22. Twardoski B, Feldmann H, Bloom M, Ward J. Modern dosimetric tools for (60)Co irradiation at high containment laboratories. Int J Radiat Biol. 2011;87:1039-44 pubmed publisher
    ..The film dosimeter used in this study can be utilized to eliminate potential for improperly administering γ-radiation doses. ..
  23. Yates E, Balling P, Petersen J, Christensen M, Skyt P, Bassler N, et al. Characterization of the optical properties and stability of Presage™ following irradiation with photons and carbon ions. Acta Oncol. 2011;50:829-34 pubmed publisher
    ..e. bleaching) of Presage™ postirradiation...
  24. Cadman P. An investigation of beam parameters for Co-60 tomotherapy. Med Phys. 2007;34:3838-43 pubmed
    ..In general it may be concluded that commercially available cylindrical Co-60 sources of 1.5-2.0 cm diameter may be appropriate for tomotherapy if the proper combination of beam parameters is chosen...
  25. Alok A, Adhikari J, Chaudhury N. Radioprotective role of clinical drug diclofenac sodium. Mutat Res. 2013;755:156-62 pubmed publisher
    ..5% of C57BL/6 mice at a lethal irradiation dose of 9Gy. Therefore, this molecule offers a potential radioprotective ability besides being used routinely as analgesic and anti inflammatory compound. ..
  26. Wasserman M, Bartoly F, Viana A, Silva M, Rochedo E, Perez D, et al. Soil to plant transfer of 137Cs and 60Co in Ferralsol, Nitisol and Acrisol. J Environ Radioact. 2008;99:546-53 pubmed
    ..This information should provide support for adequate choices of countermeasures to be applied on tropical soils in case of accident or for remediation purposes...
  27. Udhayakumar J, Pardeshi G, Gandhi S, Chakravarty R, Kumar M, Dash A, et al. Development of technology for the large-scale preparation of 60Co polymer film source. Appl Radiat Isot. 2008;66:1825-9 pubmed publisher
    ..A large film was prepared using the polymer solution containing the complex. The polymer film was then cut into circular sources, mounted on a source holder and supplied to various users...
  28. Lal P, Pal L, Kumar S, Dimri K, Tiwari A, Rastogi N, et al. Implications of p53 over-expression in the outcome with radiation in head and neck cancers. J Cancer Res Ther. 2007;3:17-22 pubmed
    ..Abnormalities in the p53 tumor suppressor gene and in the expression of its protein are commonly seen in several tumors. The prognostic implication of these p53 abnormalities was studied in 55 patients with advanced head and neck cancers...
  29. Lammers T, Peschke P, Ehemann V, Debus J, Slobodin B, Lavi S, et al. Role of PP2Calpha in cell growth, in radio- and chemosensitivity, and in tumorigenicity. Mol Cancer. 2007;6:65 pubmed
    ..By comparing the growth of tumors established from both types of cells, we also evaluated the involvement of PP2Calpha in tumorigenesis...
  30. Liu H, Chen X, Pan Z, Zhang Y. [The synergistic and toxicity-reducing effects of zhenqifuzheng injection on mice with 60Co radiotherapy]. Zhong Yao Cai. 2009;32:1711-5 pubmed
    ..To study the synergistic and toxicity-reducing effect of zhenqifuzheng (ZQFZ) injection on mice with 60Co radiotherapy...
  31. Andreo P, Wulff J, Burns D, Palmans H. Consistency in reference radiotherapy dosimetry: resolution of an apparent conundrum when (60)Co is the reference quality for charged-particle and photon beams. Phys Med Biol. 2013;58:6593-621 pubmed publisher
    ..Also in these advanced radiotherapy modalities, the need for maintaining data consistency in an analysis that unavoidably must include the complete dosimetry chain is demonstrated. ..
  32. Roivainen P, Makkonen S, Holopainen T, Juutilainen J. Transfer of elements relevant to radioactive waste from soil to five boreal plant species. Chemosphere. 2011;83:385-90 pubmed publisher
    ..However, large within-species variation suggests that it is not justified to use different CR values for modelling soil-to-plant transfer of these elements in the different boreal forest plant species...
  33. Shahidi M, Mozdarani H, Bryant P. Radiation sensitivity of leukocytes from healthy individuals and breast cancer patients as measured by the alkaline and neutral comet assay. Cancer Lett. 2007;257:263-73 pubmed
    ..Although similar initial radiosensitivity was observed for both groups but the repair kinetics of radiation-induced DNA damage of leukocytes from breast cancer cases and healthy subjects was statistically different...
  34. Uzawa A, Ando K, Koike S, Furusawa Y, Matsumoto Y, Takai N, et al. Comparison of biological effectiveness of carbon-ion beams in Japan and Germany. Int J Radiat Oncol Biol Phys. 2009;73:1545-51 pubmed publisher
    ..To compare the biological effectiveness of 290 MeV/amu carbon-ion beams in Chiba, Japan and in Darmstadt, Germany, given that different methods for beam delivery are used for each...
  35. Shimizu K, Matuo Y, Izumi Y, Ikeda T. Fundamental study of the radiation monitoring system based on evaluation of DNA lesions. Radiat Prot Dosimetry. 2011;146:62-4 pubmed publisher
  36. Martisíková M, Ackermann B, Jäkel O. Analysis of uncertainties in Gafchromic EBT film dosimetry of photon beams. Phys Med Biol. 2008;53:7013-27 pubmed publisher
    ..Although Gafchromic EBT films have significant advantages, there are certain effects which have to be considered in order to achieve 5% accuracy in the dose delivered to a patient...
  37. Petrás M, Lajtos T, Friedlander E, Klekner A, Pintye E, Feuerstein B, et al. Molecular interactions of ErbB1 (EGFR) and integrin-?1 in astrocytoma frozen sections predict clinical outcome and correlate with Akt-mediated in vitro radioresistance. Neuro Oncol. 2013;15:1027-40 pubmed publisher
    ..In addition to overexpression of ErbB1/EGFR, functional crosstalk between receptor tyrosine kinases and cell adhesion molecules may also contribute to therapy resistance...
  38. Anton M, Kapsch R, Krystek M, Renner F. Response of the alanine/ESR dosimetry system to MV X-rays relative to (60)Co radiation. Phys Med Biol. 2008;53:2753-70 pubmed publisher
    ..It is important to note that the formulae derived to obtain the final results follow from first principles, without recurring to ad hoc solutions or simple recipes and are valid for all kinds of repetitive measurements...
  39. Koskinas M, Moreira D, Yamazaki I, de Toledo F, Brancaccio F, Dias M. Primary standardization of 57Co. Appl Radiat Isot. 2010;68:1344-8 pubmed publisher
    ..The final activity obtained by the Monte Carlo calculation agrees with the experimental results within the experimental uncertainty...
  40. Plecas I. Modeling of transport phenomena in concrete porous media. Health Phys. 2014;106:S30-3 pubmed publisher
    ..The results presented in this paper are from a 25-y mortar and concrete testing project that will influence the design choices for radioactive waste packaging for a future Serbian radioactive waste disposal center...
  41. Sakashita T, Hamada N, Kawaguchi I, Ouchi N, Hara T, Kobayashi Y, et al. A framework for analysis of abortive colony size distributions using a model of branching processes in irradiated normal human fibroblasts. PLoS ONE. 2013;8:e70291 pubmed publisher
    ..Our present model provides a single framework for understanding the behavior of primary cell colonies in culture following irradiation. ..
  42. Eriksson D, Löfroth P, Johansson L, Riklund K, Stigbrand T. Apoptotic signalling in HeLa Hep2 cells following 5 Gy of cobalt-60 gamma radiation. Anticancer Res. 2009;29:4361-6 pubmed
    ..The apoptotic signalling pathways involved in the delayed type of apoptosis occurring in HeLa Hep2 cells following radiation were investigated...
  43. Weber W, Doyle Eisele M, Seilkop S, Guilmette R. Biokinetics of systemically distributed 60Co in the rat: an experimental model useful in evaluating medical countermeasures for internal contamination. Health Phys. 2012;103:474-83 pubmed publisher
  44. Li F, Jia H, Yu C. ACL reconstruction in a rabbit model using irradiated Achilles allograft seeded with mesenchymal stem cells or PDGF-B gene-transfected mesenchymal stem cells. Knee Surg Sports Traumatol Arthrosc. 2007;15:1219-27 pubmed
    ..PDGF-B transfected MSCs could also lead to an initial promotion of angiogenesis. This gene transfer technique or cell implantation may be a potentially useful tool for improving ligament remodeling...
  45. Yen P, Yang C, Chang P, Hwang J, Lee H, Kuo K, et al. Perception of quality of life of a cohort population years after relocation from previous low-dose radiation exposure in Co-60 contaminated buildings in Taiwan. Int J Radiat Biol. 2011;87:453-60 pubmed publisher
    ..To evaluate measures of health-related quality of life in a cohort study in Taiwan to assess late health effects of protracted low-dose-rate ?-radiation exposure during 1982 to the mid-1990s...
  46. Abdel Rahman W, Evans M, Serre L, McCaffrey J, Podgorsak E, Seuntjens J. Clinic based transfer of the N(D,W)(60Co) calibration coefficient using a linear accelerator. Med Phys. 2009;36:929-38 pubmed
  47. LEVITSKAIA T, Creim J, Curry T, Luders T, Morris J, Sinkov S, et al. Investigation of chitosan for decorporation of 60Co in the rat. Health Phys. 2009;97:115-24 pubmed publisher
    ..Overall, this commercially available chitosan oligosaccharide exhibited promising potential; further studies are warranted to evaluate the optimal dosing regimen and chemical modifications to increase effectiveness...
  48. Li C, Ko R, Moodie G, Kramer G. Evaluating the performance of the ORTEC® Detective™ for emergency urine bioassay. Radiat Prot Dosimetry. 2011;147:474-9 pubmed publisher
    ..30 requirements even at 10 % RL. At 1 % RL, (169)Yb and (192)Ir were not detectable at either geometry, while the measurement of (60)Co in the mixed radionuclides satisfied the ANSI N13.30 requirements only at the IG...
  49. Wang P, Zhen H, Jiang X, Zhang W, Cheng X, Guo G, et al. Boron neutron capture therapy induces apoptosis of glioma cells through Bcl-2/Bax. BMC Cancer. 2010;10:661 pubmed publisher
    ..The aim of this study was to determine whether induction of apoptosis contributes to the main therapeutic efficacy of BNCT and to compare the relative biological effect (RBE) of BNCT, ?-ray and reactor neutron irradiation...
  50. Avila Rodriguez M, Nye J, Nickles R. Simultaneous production of high specific activity 64Cu and 61Co with 11.4 MeV protons on enriched 64Ni nuclei. Appl Radiat Isot. 2007;65:1115-20 pubmed
    ..Experimental thick target saturation yields of 159 mCi/microA for (64)Cu and 715 microCi/microA for (61)Co were achieved. Typical specific activities of (64)Cu were found to be 18.8+/-3.3 Ci/micromol...
  51. Eriksson D, Löfroth P, Johansson L, Riklund K, Stigbrand T. Cell cycle disturbances and mitotic catastrophes in HeLa Hep2 cells following 2.5 to 10 Gy of ionizing radiation. Clin Cancer Res. 2007;13:5501s-5508s pubmed
    ..5 to 10 Gy has been shown to cause growth retardation of tumors. The purpose of this study was to elucidate the sequential molecular and cellular events occurring in HeLa Hep2 cells exposed to such doses...
  52. Tabrizi S, Asl A, Azma Z. Monte Carlo derivation of AAPM TG-43 dosimetric parameters for GZP6 Co-60 HDR sources. Phys Med. 2012;28:153-60 pubmed publisher
    ..The TG-43 based dosimetry data can be used not only to validate the dedicated treatment planning software (TPS), but also to introduce new complementary software to enhance the system performance in gynecological treatments...
  53. Olsvik P, Heier L, Rosseland B, Teien H, Salbu B. Effects of combined gamma-irradiation and metal (Al+Cd) exposures in Atlantic salmon (Salmo salar L.). J Environ Radioact. 2010;101:230-6 pubmed publisher