calcium radioisotopes

Summary

Summary: Unstable isotopes of calcium that decay or disintegrate emitting radiation. Ca atoms with atomic weights 39, 41, 45, 47, 49, and 50 are radioactive calcium isotopes.

Top Publications

  1. Tsuchita H, Suzuki T, Kuwata T. The effect of casein phosphopeptides on calcium absorption from calcium-fortified milk in growing rats. Br J Nutr. 2001;85:5-10 pubmed
    ..The mechanism of CPP related to the interaction of CPP and Ca in the gastrointestinal tract is discussed...
  2. Machida K, Ishibashi R, Hara T, Ohtsuka A, Hayashi K. Effects of corticosterone on Ca2+ uptake and myofibrillar disassembly in primary muscle cell culture. Biosci Biotechnol Biochem. 2003;67:244-9 pubmed
    ..These results show that corticosterone increases Ca2+ uptake and starts myofibrillar protein breakdown...
  3. Fahey M, Mitton E, Muth E, Rosenthal A. Dexamethasone promotes calcium pyrophosphate dihydrate crystal formation by articular chondrocytes. J Rheumatol. 2009;36:163-9 pubmed publisher
    ..Dxm has variable effects in mineralization models. We investigated the effects of Dxm on CPPD crystal formation in a well established tissue culture model...
  4. Schönekess B, Walsh M. Molecular cloning and expression of avian smooth muscle S100A11 (calgizzarin, S100C). Biochem Cell Biol. 1997;75:771-5 pubmed
  5. Han H, Park S, Lee Y. Epidermal growth factor regulates Ca2+ uptake in primary cultured renal proximal tubule cells: involvement of cAMP, PKC and cPLA2. Kidney Blood Press Res. 2003;26:155-64 pubmed
    ..These results suggest that cAMP, PLC/PKC, and PLA(2) are involved in EGF-induced stimulation of Ca(2+) uptake...
  6. Goldberg M, Choi D. Combined oxygen and glucose deprivation in cortical cell culture: calcium-dependent and calcium-independent mechanisms of neuronal injury. J Neurosci. 1993;13:3510-24 pubmed
    ..Delayed neuronal degeneration depends on the presence of extracellular Ca2+ and correlates closely with cellular uptake of 45Ca2+...
  7. Mahaney J, Albers R, Waggoner J, Kutchai H, Froehlich J. Intermolecular conformational coupling and free energy exchange enhance the catalytic efficiency of cardiac muscle SERCA2a following the relief of phospholamban inhibition. Biochemistry. 2005;44:7713-24 pubmed
    ..We propose that intermolecular coupling of SERCA2a molecules during catalytic cycling is obligatory for the changes in Ca2+ transport activity that accompany the relief of PLB inhibition of the cardiac SR Ca2+-ATPase...
  8. Steele J, Ireland R. Hormonal activation of phosphorylase in cockroach fat body trophocytes: A correlation with trans-membrane calcium flux. Arch Insect Biochem Physiol. 1999;42:233-44 pubmed
    ..The Ca(2+) fluxes are consistent with its postulated role in the activation of phosphorylase. Arch...
  9. Iwamoto T, Kita S, Uehara A, Imanaga I, Matsuda T, Baba A, et al. Molecular determinants of Na+/Ca2+ exchange (NCX1) inhibition by SEA0400. J Biol Chem. 2004;279:7544-53 pubmed

More Information

Publications62

  1. Juneja R, Kadam P, Kadam A, Koide S. Inhibition of progesterone action by a factor in human follicular fluid. Horm Metab Res. 1993;25:298-300 pubmed
    ..The active fraction is effective at a concentration of 200 micrograms/ml. The present findings suggest that hFF factor may regulate the metabolism of progesterone sensitive cells...
  2. Lucas Heron B, Schmitt N, Ollivier B. Mdx mouse skeletal muscle: could a mitochondrial factor be responsible for the absence of progressive necrosis?. Neurosci Lett. 1994;169:97-100 pubmed
    ..However, the muscles of patients with Duchenne muscular dystrophy (DMD) are lacking in calmitine and are subject to extensive progressive degeneration...
  3. Fitzgerald R, Hillegonds D, Burton D, Griffin T, Mullaney S, Vogel J, et al. 41Ca and accelerator mass spectrometry to monitor calcium metabolism in end stage renal disease patients. Clin Chem. 2005;51:2095-102 pubmed
    ..We report the preparation of an intravenous (41)Ca dose suitable for humans, an analytical method for determining (41)Ca/Ca isotope ratios in biological samples, and studies in human volunteers...
  4. Martino H, Martin B, Weaver C, Bressan J, Moreira M, Costa N. A soybean cultivar lacking lipoxygenase 2 and 3 has similar calcium bioavailability to a commercial variety despite higher calcium absorption inhibitors. J Food Sci. 2008;73:H33-5 pubmed publisher
    ..05) found in the UFV-116 variety did not affect calcium absorption. Therefore, the new variety is a comparable source of high bioavailable calcium...
  5. Toru T, Konno F, Takayanagi I, Hirobe M. Kappa-receptor mechanisms in synaptosomal Ca uptake. Gen Pharmacol. 1989;20:249-52 pubmed
    ..6. The difference between the two potency orders suggests that affinities and intrinsic activities of the drugs are important factors in determining their agonistic activity in kappa-receptor mechanisms...
  6. Lee W, Wastney M, Jackson G, Martin B, Weaver C. Interpretation of 41Ca data using compartmental modeling in post-menopausal women. Anal Bioanal Chem. 2011;399:1613-22 pubmed publisher
    ..The model was used to simulate dynamic changes in urinary (41)Ca:Ca ratios and bone balance, as a result of interventions that perturb calcium metabolism to aid in study design and interpretation...
  7. Geer J, Dooley D, Adams M. K(+)-stimulated 45Ca2+ flux into rat neocortical mini-slices is blocked by omega-Aga-IVA and the dual Na+/Ca2+ channel blockers lidoflazine and flunarizine. Neurosci Lett. 1993;158:97-100 pubmed
    ..4 microM and 11 microM, respectively), which have dual Na+/Ca2+ channel blocking actions...
  8. McGarry S, Williams A. Digoxin activates sarcoplasmic reticulum Ca(2+)-release channels: a possible role in cardiac inotropy. Br J Pharmacol. 1993;108:1043-50 pubmed
    ..Further, activation of the channel by higher concentrations of digoxin may contribute to the toxic effects seen clinically...
  9. Lott J, Fitchie J, Creasy M, Puckett A. Microleakage of three conventional glass ionomers using 45Ca and methylene blue. Gen Dent. 2007;55:15-8 pubmed
    ..The results showed that all of the materials investigated performed well and no statistical differences were found among the materials, the tracer used, or the margin evaluated...
  10. Hunt J, Johnson L, Fariba Roughead Z. Dietary protein and calcium interact to influence calcium retention: a controlled feeding study. Am J Clin Nutr. 2009;89:1357-65 pubmed publisher
    ..The effect of meat protein on calcium retention at different calcium intakes is unresolved...
  11. Kung A, Luk K, Chu L, Chiu P. Age-related osteoporosis in Chinese: an evaluation of the response of intestinal calcium absorption and calcitropic hormones to dietary calcium deprivation. Am J Clin Nutr. 1998;68:1291-7 pubmed
    ..Age-related osteoporosis may be associated with inefficient intestinal calcium absorption and bone remodeling...
  12. Endo A, Yamaguchi Y. Analysis of dose distribution for heavily exposed workers in the first criticality accident in Japan. Radiat Res. 2003;159:535-42 pubmed
  13. Parija S, Raviprakash V, Telang A, Varshney V, Mishra S. Influence of hypothyroid state on 45Ca(2+) influx and sensitivity of rat uterus to nifedipine and diltiazem. Eur J Pharmacol. 2001;421:207-13 pubmed
    ..The results of the present study suggest that the inhibition of uterine rhythmic contractions may be attributable to a reduction in rat myometrial Ca2+ channel function in the hypothyroid state...
  14. Little R, Muimo R, Robson L, Harris K, Grabowski P. The transient receptor potential ion channel TRPV6 is expressed at low levels in osteoblasts and has little role in osteoblast calcium uptake. PLoS ONE. 2011;6:e28166 pubmed publisher
    ..TRPV6 and molecules related to transepithelial Ca2+ transport have been reported to be expressed at high levels in human and mouse osteoblasts...
  15. Takeda H, Miyamoto K, Yukawa M, Nishimura Y, Watanabe Y, Kim H, et al. Bioassay for neutron-dose estimations of three patients in the JCO criticality accident in Tokai-mura by measuring beta-ray emitters. J Radiat Res. 2001;42 Suppl:S129-35 pubmed
  16. Smith E, Need A, Schultz C, Horowitz M. Does the response of bone mass to calcium supplements depend on calcium absorption efficiency?. Eur J Endocrinol. 2004;151:759-63 pubmed
  17. de Almeida J, Platt J, Oshida Y, Moore B, Cochran M, Eckert G. Three different methods to evaluate microleakage of packable composites in Class II restorations. Oper Dent. 2003;28:453-60 pubmed
    ..The results showed that Rhodamine B detected more microleakage than 45Ca or methylene blue, and 45Ca generally detected more microleakage than methylene blue...
  18. Kim M, Jung Y, Lee K, Kim C. Identification of the calcium binding sites in translationally controlled tumor protein. Arch Pharm Res. 2000;23:633-6 pubmed
    ..Thus, our data confirm that TCTP is a novel family of Ca2+ -binding protein...
  19. Leffler P, Jin T, Nordberg G. Differential calcium transport disturbances in renal membrane vesicles after cadmium-metallothionein injection in rats. Toxicology. 2000;143:227-34 pubmed
    ..Metal analysis verified a four-fold increase of Ca in kidney cortex at 24 h. This suggests that Cd impact on tubular cells involves disturbances on cellular absorption as well as expulsion of Ca...
  20. Hofmann S, Brown M, Lee E, Pathak R, Anderson R, Goldstein J. Purification of a sarcoplasmic reticulum protein that binds Ca2+ and plasma lipoproteins. J Biol Chem. 1989;264:8260-70 pubmed
    ..The role of the 165-kDa protein in Ca2+ homeostasis in the sarcoplasmic reticulum, if any, remains to be determined...
  21. Popper L, Batra S. Release of intracellular calcium by prenylamine in human ovarian tumour cells. Cancer Lett. 1993;71:5-10 pubmed
    ..These results, although paradoxical, provide a new insight into the possible mechanism of action of prenylamine in causing cancer cell death...
  22. Hölttä P, Siitari Kauppi M, Hakanen M, Tukiainen V. Attempt to model laboratory-scale diffusion and retardation data. J Contam Hydrol. 2001;47:139-48 pubmed
    ..Kd values obtained from fracture column experiments were one order of magnitude lower than Kd values from batch experiments...
  23. Weaver C, Martin B, Jackson G, McCabe G, Nolan J, McCabe L, et al. Antiresorptive effects of phytoestrogen supplements compared with estradiol or risedronate in postmenopausal women using (41)Ca methodology. J Clin Endocrinol Metab. 2009;94:3798-805 pubmed publisher
    ..Isoflavones have been reported to protect bone from estrogen deficiency, but their modest effects on bone resorption have been difficult to measure with traditional analytical methods...
  24. Pocock G, Richards C. The action of volatile anaesthetics on stimulus-secretion coupling in bovine adrenal chromaffin cells. Br J Pharmacol. 1988;95:209-17 pubmed
    ..Similar actions at synapses within the CNS may underlie the general anaesthetic effects of these agents...
  25. Burd P, Ferry C, Smith J. Accumulation of extracellular calcium at the endplate of mouse diaphragm after ecothiopate in vitro. Br J Pharmacol. 1989;98:243-51 pubmed
  26. Chen S, Roufogalis B. Enhanced 45Ca2+ efflux in cultured vascular smooth muscle cells from spontaneously hypertensive rats. Am J Hypertens. 1994;7:597-602 pubmed
    ..An increase in intracellular [Ca2+]i may be compensated for by enhanced Ca(2+)-pump and Na(+)-Ca2+ exchange activities in VSMC in hypertension...
  27. Li Z, Lin Q, Yang D, Ewart K, Hew C. The role of Ca2+-coordinating residues of herring antifreeze protein in antifreeze activity. Biochemistry. 2004;43:14547-54 pubmed
    ..These data indicate that the ice-binding site of hAFP is located at the Ca(2+)-binding site and the loop region defined by residues 99 and 114 is important for antifreeze activity...
  28. Shih L, Shih H, Chen T. Bone resorption activity of osteolytic metastatic lung and breast cancers. J Orthop Res. 2004;22:1161-7 pubmed
    ..Our observation showed that PGE2 was produced by osteolytic metastatic cancers and stimulated bone resorption in mice calvarias. PGE2 inhibitor may be applicable in reducing bone resorption by osteolytic metastatic cancers...
  29. Henzl M, Larson J, Agah S. Influence of monovalent cation identity on parvalbumin divalent ion-binding properties. Biochemistry. 2004;43:2747-63 pubmed
    ..8 x 10(6) M(-1) and the latter to 1.4 x 10(4) and 2.9 x 10(2) M(-1). These data suggest that parvalbumin divalent ion affinity, particularly that of rat alpha, can be significantly attenuated by increased intracellular Na(+) levels...
  30. Hyde G, Seale A, Grau E, Borski R. Cortisol rapidly suppresses intracellular calcium and voltage-gated calcium channel activity in prolactin cells of the tilapia (Oreochromis mossambicus). Am J Physiol Endocrinol Metab. 2004;286:E626-33 pubmed
    ..These results provide further evidence that glucocorticoids rapidly modulate hormone secretion via a membrane-associated mechanism similar to that observed with the fast effects of peptides and neurotransmitters...
  31. Correa V, Riley A, Shuto S, Horne G, Nerou E, Marwood R, et al. Structural determinants of adenophostin A activity at inositol trisphosphate receptors. Mol Pharmacol. 2001;59:1206-15 pubmed
    ..This is the first comprehensive analysis of all the key structural elements of adenophostin A, and it provides a working model for the design of related high-affinity ligands of InsP(3) receptors...
  32. Theron A, Steel H, Tintinger G, Anderson R. Endogenous adenosine regulates neutrophil pro-inflammatory activities by cyclic AMP-dependent accelerated clearance of cytosolic calcium. Inflamm Res. 2002;51:594-602 pubmed
    ..To identify the involvement of adenosine in restoration of Ca2+ homeostasis to activated human neutrophils...
  33. Beauchamp G, Lavoie P, Elie R. Effect of trimipramine on depolarization-induced and Na(+)-Ca2+ exchange-induced 45calcium uptake in synaptosomes from the cortex of the rat brain. Neuropharmacology. 1992;31:229-34 pubmed
  34. Ramagopal M, Mustafa S. Extracellular calcium-dependent and -independent effects of adenosine in bovine coronary artery. Can J Physiol Pharmacol. 1990;68:608-13 pubmed
    ..The data suggest that the vasodilatory action of adenosine in bovine coronary smooth muscle has both extracellular calcium-dependent and -independent components...
  35. Tsang S, Wong S, Wu S, Kravtsov G, Wong T. Testosterone-augmented contractile responses to alpha1- and beta1-adrenoceptor stimulation are associated with increased activities of RyR, SERCA, and NCX in the heart. Am J Physiol Cell Physiol. 2009;296:C766-82 pubmed publisher
    ..The increased contractility and speedier relaxation were associated with increased Ca(2+) release via the RyR and faster Ca(2+) removal out of the cytosol via SERCA and NCX...
  36. Gorodeski G. Expression, regulation, and function of P2X(4) purinergic receptor in human cervical epithelial cells. Am J Physiol Cell Physiol. 2002;282:C84-93 pubmed
    ..However, in contrast to phase II response, both RAR and RXR agonists could fully reverse those effects. These results suggest that phase II response is mediated by a P2X(4) receptor mechanism...
  37. Nicoud I, Knox C, Jones C, Anderson C, Pierce J, Belous A, et al. 2-APB protects against liver ischemia-reperfusion injury by reducing cellular and mitochondrial calcium uptake. Am J Physiol Gastrointest Liver Physiol. 2007;293:G623-30 pubmed
  38. Perez Vizcaino F, Fernandez del Pozo B, Zaragoza F, Tamargo J. Voltage- and time-dependent inhibitory effects on rat aortic and porcine coronary artery contraction induced by propafenone and quinidine. Br J Pharmacol. 1994;113:1281-8 pubmed
    ..The voltage- and time-dependent inhibitory effects of quinidine may reflect an increased binding of the drug to Ca2+ channels at depolarized potentials...
  39. Heaney R. Measuring what isn't there. Clin Chem. 2005;51:2003-4 pubmed
  40. Roy B, Sicotte B, Brochu M, St Louis J. Modulation of calcium mobilization in aortic rings of pregnant rats: Contribution of extracellular calcium and of voltage-operated calcium channels. Biol Reprod. 1999;60:979-88 pubmed
    ..These results indicate an altered extracellular calcium mobilization of aortic rings from pregnant rats. These changes may be due to a functional alteration of the voltage-operated calcium channels during pregnancy...
  41. Lehmler H, Robertson L, Garrison A, Kodavanti P. Effects of PCB 84 enantiomers on [3H]-phorbol ester binding in rat cerebellar granule cells and 45Ca2+-uptake in rat cerebellum. Toxicol Lett. 2005;156:391-400 pubmed
  42. Pekkarinen T, Lindholm T, Hietala O, Jalovaara P. The effect of different mineral frames on ectopic bone formation in mouse hind leg muscles induced by native reindeer bone morphogenetic protein. Arch Orthop Trauma Surg. 2005;125:10-5 pubmed
    ..Bone morphogenetic proteins (BMPs) require carrier material for slow release and framing material for osteoconduction...
  43. Lerner U, Modeer T, Krekmanova L, Claesson R, Rasmussen L. Gingival crevicular fluid from patients with periodontitis contains bone resorbing activity. Eur J Oral Sci. 1998;106:778-87 pubmed
    ..The data indicate that other factors, such as IL-1, may play key roles in the stimulation of osteoclastic activity by gingival crevicular washings...
  44. Tang H, Inoue A, Oshita K, Nakata Y. Sensitization of vanilloid receptor 1 induced by bradykinin via the activation of second messenger signaling cascades in rat primary afferent neurons. Eur J Pharmacol. 2004;498:37-43 pubmed
    ..These data suggest that endogenous substances produced by several enzymes may be capable of producing a synergistic response involving the vanilloid receptor 1...
  45. Mathias P, Salvato E, Curi R, Malaisse W, Carpinelli A. Effect of epinephrine on 86Rb efflux, 45Ca outflow and insulin release from pancreatic islets perifused in the presence of propranolol. Horm Metab Res. 1993;25:138-41 pubmed
  46. Grigor ev V, Ivanova T, Kustova E, Petrova L, Serkova T, Bachurin S. Effects of delta sleep-inducing peptide on pre- and postsynaptic glutamate and postsynaptic GABA receptors in neurons of the cortex, hippocampus, and cerebellum in rats. Bull Exp Biol Med. 2006;142:186-8 pubmed
    ..The peptide modulates activity of presynaptic NMDA receptors, which is seen from changes in (45)Ca(2+) uptake into synaptosomes of the brain cortex after uptake stimulation with glutamate and NMDA...
  47. Mongin A, Aksentsev S, Orlov S, Konev S. Hypoosmotic shock activates Ca2+ channels in isolated nerve terminals. Neurochem Int. 1997;31:835-43 pubmed
    ..Activation of these channels may constitute an early event in volume regulation of nerve terminals in anisoosmotic conditions...
  48. Miyamoto Y, Yamada K, Noda Y, Mori H, Mishina M, Nabeshima T. Lower sensitivity to stress and altered monoaminergic neuronal function in mice lacking the NMDA receptor epsilon 4 subunit. J Neurosci. 2002;22:2335-42 pubmed
    ..These findings suggest that GluRepsilon4 mutant mice have dysfunctional NMDA receptors and altered emotional behavior probably caused by changes in monoaminergic neuronal activities in adulthood...
  49. Emoto Y, Kobayashi R, Akatsuka H, Hidaka H. Purification and characterization of a new member of the S-100 protein family from human placenta. Biochem Biophys Res Commun. 1992;182:1246-53 pubmed
    ..A ninety amino acid sequence of S-100P was determined. It is 49% identical with human S-100 beta, 38% with human calcyclin, and 37% with human cystic fibrosis antigen...
  50. Houlbrèque F, Tambutte E, Allemand D, Ferrier Pages C. Interactions between zooplankton feeding, photosynthesis and skeletal growth in the scleractinian coral Stylophora pistillata. J Exp Biol. 2004;207:1461-9 pubmed
    ..Our results suggest that the increase in the rates of calcification in fed corals might be induced by a feeding-stimulation of organic matrix synthesis...
  51. Kurihara K, Nakanishi N, Ueha T. A calcium channel in human submandibular duct cell line, HSG cells, not regulated by P2U purinergic receptor-mediated intracellular calcium mobilization. Arch Oral Biol. 1997;42:547-57 pubmed
    ..Thus, in HSG cells, IP3 formation is coupled to the P2U subclass, while 45Ca2+ influx is coupled to another subclass, such as P2X, that regulates calcium channels...
  52. Azuma M, Houchi H, Nishisako H, Ishizawa K, Tsuchiya K, Teraoka K, et al. Inhibitory action of novel arginine derivative on catecholamine secretion evoked by acetylcholine from cultured bovine adrenal chromaffin cells. J Cardiovasc Pharmacol. 2003;42 Suppl 1:S15-8 pubmed
  53. Lyaruu D, van Duin M, Bervoets T, Woltgens J, Bronckers A. Effects of actinomycin D on developing hamster molar tooth germs in vitro. Eur J Oral Sci. 1997;105:52-8 pubmed