isotopes

Summary

Summary: Atomic species differing in mass number but having the same atomic number. (Grant & Hackh's Chemical Dictionary, 5th ed)

Top Publications

  1. Hobson K, Van Wilgenburg S, Wassenaar L, Larson K. Linking hydrogen (δ2H) isotopes in feathers and precipitation: sources of variance and consequences for assignment to isoscapes. PLoS ONE. 2012;7:e35137 pubmed publisher
    ..Naturally occurring stable isotopes of H (δ(2)H) in feathers provide an alternative intrinsic marker of animal origin due to the predictable ..
  2. Gupta V, Smemo K, Yavitt J, Fowle D, Branfireun B, Basiliko N. Stable isotopes reveal widespread anaerobic methane oxidation across latitude and peatland type. Environ Sci Technol. 2013;47:8273-9 pubmed publisher
    ..Globally, we estimate that AOM could consume a large proportion of CH4 produced annually (1.6-49 Tg) and thereby constrain emissions and greenhouse gas forcing. ..
  3. Crotty D, Silkstone G, Poddar S, Ranson R, Prina Mello A, Wilson M, et al. Reexamination of magnetic isotope and field effects on adenosine triphosphate production by creatine kinase. Proc Natl Acad Sci U S A. 2012;109:1437-42 pubmed publisher
  4. Hopkins J, Ferguson J. Estimating the diets of animals using stable isotopes and a comprehensive Bayesian mixing model. PLoS ONE. 2012;7:e28478 pubmed publisher
    ..IsotopeR's user interface (in R) will provide researchers a user-friendly tool for SIMM analysis. The model is also applicable for use in paleontology, archaeology, and forensic studies as well as estimating pollution inputs. ..
  5. Bairlein F, Norris D, Nagel R, Bulte M, Voigt C, Fox J, et al. Cross-hemisphere migration of a 25 g songbird. Biol Lett. 2012;8:505-7 pubmed publisher
    ..Our results provide the first evidence of a migratory songbird capable of linking African ecosystems of the Old World with Arctic regions of the New World...
  6. Kuo T, Wang C, Lin H, Lin Y, Lin M, Lin C, et al. Assessment of renal function by the stable oxygen and hydrogen isotopes in human blood plasma. PLoS ONE. 2012;7:e32137 pubmed publisher
    Water (H(2)O) is the most abundant and important molecule of life. Natural water contains small amount of heavy isotopes. Previously, few animal model studies have shown that the isotopic composition of body water could play important ..
  7. Hussey N, MacNeil M, Olin J, McMeans B, Kinney M, Chapman D, et al. Stable isotopes and elasmobranchs: tissue types, methods, applications and assumptions. J Fish Biol. 2012;80:1449-84 pubmed publisher
    ..Recommendations are made for future SIA experimental work that would improve understanding of stable-isotope dynamics and advance their application in the study of sharks, skates and rays...
  8. Alter S, Newsome S, Palumbi S. Pre-whaling genetic diversity and population ecology in eastern Pacific gray whales: insights from ancient DNA and stable isotopes. PLoS ONE. 2012;7:e35039 pubmed publisher
    ..Stable isotopes show minimal differences between modern and ancient gray whale foraging ecology...
  9. Gao B, Liang X, Zhou H, Tu X. Lead isotopes as a tracer of Pb origin in the sediments from Beijiang River, South China. Water Sci Technol. 2012;66:2613-9 pubmed publisher
    ..The mining activities and metal smelting processing was the main source of Pb pollution in this region...

Scientific Experts

More Information

Publications62

  1. Ceriani S, Roth J, Evans D, Weishampel J, Ehrhart L. Inferring foraging areas of nesting loggerhead turtles using satellite telemetry and stable isotopes. PLoS ONE. 2012;7:e45335 pubmed publisher
    In recent years, the use of intrinsic markers such as stable isotopes to link breeding and foraging grounds of migratory species has increased...
  2. Six J, Hughes Riley T, Stupic K, Pavlovskaya G, Meersmann T. Pathway to cryogen free production of hyperpolarized Krypton-83 and Xenon-129. PLoS ONE. 2012;7:e49927 pubmed publisher
    ..Aspects of SEOP specific to the two noble gas isotopes are discussed and compared with current theoretical opinions...
  3. Wu J, Liu D, Xie Q, Wang J. Biological fractionation of lead isotopes in Sprague-Dawley rats lead poisoned via the respiratory tract. PLoS ONE. 2012;7:e52462 pubmed publisher
    ..An animal experiment was conducted to explore the biological fractionation of lead isotopes in biological systems.
  4. Weiss D, Rehkämper M, Schoenberg R, McLaughlin M, Kirby J, Campbell P, et al. Application of nontraditional stable-isotope systems to the study of sources and fate of metals in the environment. Environ Sci Technol. 2008;42:655-64 pubmed
  5. Schramm V. Binding isotope effects: boon and bane. Curr Opin Chem Biol. 2007;11:529-36 pubmed
    ..Although binding isotope effects complicate kinetic isotope effect analysis, they also provide a powerful tool for finding atomic distortion in molecular interactions...
  6. Patel M, Adrianne H, Jones R, Jarrett J, BERNER J, Rubin C. Use of lead isotope ratios to identify sources of lead exposure in Alaska Natives. Int J Circumpolar Health. 2008;67:261-8 pubmed
    ..The Centers for Disease Control and Prevention (CDC) and Alaskan health officials conducted a cross-sectional exposure assessment and used isotope ratios (IR) to test that assumption...
  7. Cheng H, Hu Y. Lead (Pb) isotopic fingerprinting and its applications in lead pollution studies in China: a review. Environ Pollut. 2010;158:1134-46 pubmed publisher
    ..Further methodological developments and more widespread instrument availability are expected to make isotopic fingerprinting one of the key tools in lead pollution investigation...
  8. Stupic K, Elkins N, Pavlovskaya G, Repine J, Meersmann T. Effects of pulmonary inhalation on hyperpolarized krypton-83 magnetic resonance T1 relaxation. Phys Med Biol. 2011;56:3731-48 pubmed publisher
    ..Further, the (83)Kr T(1) relaxation times in excised lungs were unaffected by the presence of up to 40% oxygen in the hp gas mixture. The results support the possible importance of (83)Kr as a biomarker for evaluating lung function...
  9. Carnielli V, Zimmermann L, Hamvas A, Cogo P. Pulmonary surfactant kinetics of the newborn infant: novel insights from studies with stable isotopes. J Perinatol. 2009;29 Suppl 2:S29-37 pubmed publisher
    ..Information obtained from these studies in infants will help to better tailor exogenous surfactant treatment in neonatal lung diseases...
  10. Nestler A, Berglund M, Accoe F, Duta S, Xue D, Boeckx P, et al. Isotopes for improved management of nitrate pollution in aqueous resources: review of surface water field studies. Environ Sci Pollut Res Int. 2011;18:519-33 pubmed publisher
    ..Isotope data can support the identification of nitrate pollution sources and natural attenuation processes of nitrate...
  11. Sellick M, Kyser T, Wunder M, Chipley D, Norris D. Geographic variation of strontium and hydrogen isotopes in avian tissue: implications for tracking migration and dispersal. PLoS ONE. 2009;4:e4735 pubmed publisher
    b>Isotopes can provide unique solutions to fundamental problems related to the ecology and evolution of migration and dispersal because prior movements of individuals can theoretically be tracked from tissues collected from a single capture...
  12. Petrotchenko E, Xiao K, Cable J, Chen Y, Dokholyan N, Borchers C. BiPS, a photocleavable, isotopically coded, fluorescent cross-linker for structural proteomics. Mol Cell Proteomics. 2009;8:273-86 pubmed publisher
  13. Mützel Rauch E, Lehn C, Peschel O, Hölzl S, Rossmann A. Assignment of unknown persons to their geographical origin by determination of stable isotopes in hair samples. Int J Legal Med. 2009;123:35-40 pubmed publisher
    ..The possibilities and limitations of this method in its current state are demonstrated and discussed...
  14. Cleveland Z, Stupic K, Pavlovskaya G, Repine J, Wooten J, Meersmann T. Hyperpolarized 83Kr and 129Xe NMR relaxation measurements of hydrated surfaces: implications for materials science and pulmonary diagnostics. J Am Chem Soc. 2007;129:1784-92 pubmed
    ..The results suggest that in vivo MR studies may be feasible and could provide valuable information about changes in pulmonary surface chemistry...
  15. Tran V, Nguyen T, Raman K, Kuberan B. Applications of isotopes in advancing structural and functional heparanomics. Anal Bioanal Chem. 2011;399:559-70 pubmed publisher
    ..This review focuses on the applications of isotopes, both radioisotopes and stable isotopes, in the structural elucidation of the complex heparanome at the ..
  16. Vander Zanden H, Bjorndal K, Reich K, Bolten A. Individual specialists in a generalist population: results from a long-term stable isotope series. Biol Lett. 2010;6:711-4 pubmed publisher
    ..Using stable isotopes of nitrogen and carbon, we examined the resource use patterns (integration of diet, habitat and geographical ..
  17. Cole J, Carpenter S, Kitchell J, Pace M, Solomon C, Weidel B. Strong evidence for terrestrial support of zooplankton in small lakes based on stable isotopes of carbon, nitrogen, and hydrogen. Proc Natl Acad Sci U S A. 2011;108:1975-80 pubmed publisher
    ..Here, we adopt a unique approach by using stable isotopes of H, C, and N to estimate terrestrial support to zooplankton in two contrasting lakes...
  18. Asante K, Agusa T, Mochizuki H, Ramu K, Inoue S, Kubodera T, et al. Trace elements and stable isotopes (delta13C and delta15N) in shallow and deep-water organisms from the East China Sea. Environ Pollut. 2008;156:862-73 pubmed publisher
    ..Positive correlations between delta13C and Rb were observed in marine organisms. Therefore, Rb may be a possible substitute of delta13C as tracer of prey source in the East China Sea although further investigation is required...
  19. Hobson K, Wunder M, Van Wilgenburg S, Clark R, Wassenaar L. A method for investigating population declines of migratory birds using stable isotopes: origins of harvested lesser scaup in North America. PLoS ONE. 2009;4:e7915 pubmed publisher
    ..Here we used hydrogen isotopes (deltaD) to determine natal origins of migrating hatch-year lesser scaup (Aythya affinis) harvested by hunters in ..
  20. Zubarev R. Role of stable isotopes in life--testing isotopic resonance hypothesis. Genomics Proteomics Bioinformatics. 2011;9:15-20 pubmed publisher
    Stable isotopes of most important biological elements, such as C, H, N and O, affect living organisms. In rapidly growing species, deuterium and to a lesser extent other heavy isotopes reduce the growth rate...
  21. Pudney C, Johannissen L, Sutcliffe M, Hay S, Scrutton N. Direct analysis of donor-acceptor distance and relationship to isotope effects and the force constant for barrier compression in enzymatic H-tunneling reactions. J Am Chem Soc. 2010;132:11329-35 pubmed publisher
    ..Further, we demonstrate that-contrary to current dogma-compression may not always cause the magnitude of the primary kinetic isotope effect to decrease...
  22. Rapisarda P, Camin F, Fabroni S, Perini M, Torrisi B, Intrigliolo F. Influence of different organic fertilizers on quality parameters and the delta(15)N, delta(13)C, delta(2)H, delta(34)S, and delta(18)O values of orange fruit (Citrus sinensis L. Osbeck). J Agric Food Chem. 2010;58:3502-6 pubmed publisher
    ..These treatments also did not effect differences in the delta(13)C, delta(2)H, delta(34)S, and delta(18)O values of fruit...
  23. Kirby M, Mathew L, Heydarian M, Etemad Rezai R, McCormack D, Parraga G. Chronic obstructive pulmonary disease: quantification of bronchodilator effects by using hyperpolarized ³He MR imaging. Radiology. 2011;261:283-92 pubmed publisher
    ..To evaluate short-acting bronchodilator effects in chronic obstructive pulmonary disease (COPD) by using hyperpolarized helium 3 (³He) magnetic resonance (MR) imaging, spirometry, and plethysmography...
  24. Nanus L, Williams M, Campbell D, Elliott E, Kendall C. Evaluating regional patterns in nitrate sources to watersheds in National Parks of the Rocky Mountains using nitrate isotopes. Environ Sci Technol. 2008;42:6487-93 pubmed
    ..Regional patterns in NO3 deposition sources were evaluated using NO3 isotopes in five National Parks, including 37 lakes and 7 precipitation sites...
  25. Chang Y, Hatch K, Ding T, Eggett D, Yuan H, Roeder B. Using stable isotopes to unravel and predict the origins of great cormorants (Phalacrocorax carbo sinensis) overwintering at Kinmen. Rapid Commun Mass Spectrom. 2008;22:1235-44 pubmed publisher
    ..We show that analyses of multiple stable isotopes (delta(13)C, delta(15)N, delta(18)O and deltaD) can provide an understanding of the number of breeding ..
  26. Neufeld J, Wagner M, Murrell J. Who eats what, where and when? Isotope-labelling experiments are coming of age. ISME J. 2007;1:103-10 pubmed
    ..Insight into the 'uncultivated majority' accompanies methodology that involves the incorporation of stable isotopes or radioisotopes into sub-populations of environmental samples...
  27. Schramm V. Enzymatic transition states, transition-state analogs, dynamics, thermodynamics, and lifetimes. Annu Rev Biochem. 2011;80:703-32 pubmed publisher
    ..Binding isotope effects (BIEs) reveal relative reactant and transition-state analog binding distortion for comparison with actual transition states...
  28. Van Wilgenburg S, Hobson K. Combining stable-isotope (deltaD) and band recovery data to improve probabilistic assignment of migratory birds to origin. Ecol Appl. 2011;21:1340-51 pubmed
    ..We show that likelihood-based assignments of geographic origins can provide improved spatial resolution when models of migration direction are combined with assignments based on deltaD analysis of feathers...
  29. Fontaine M, Tolley K, Siebert U, Gobert S, Lepoint G, Bouquegneau J, et al. Long-term feeding ecology and habitat use in harbour porpoises Phocoena phocoena from Scandinavian waters inferred from trace elements and stable isotopes. BMC Ecol. 2007;7:1 pubmed
    ..along the Scandinavian coast from the North Sea to the Barents Sea using time-integrative markers: stable isotopes (delta13C, delta15N) and trace elements (Zn, Cu, Fe, Se, total Hg and Cd), in relation to habitat characteristics ..
  30. Sturup S, Hansen H, Gammelgaard B. Application of enriched stable isotopes as tracers in biological systems: a critical review. Anal Bioanal Chem. 2008;390:541-54 pubmed
    The application of enriched stable isotopes of minerals and trace elements as tracers in biological systems is a rapidly growing research field that benefits from the many new developments in inorganic mass spectrometric instrumentation, ..
  31. Abrams S. Assessing mineral metabolism in children using stable isotopes. Pediatr Blood Cancer. 2008;50:438-41; discussion 451 pubmed
    ..These assessments can now be done safely and readily using non-radioactive, stable isotopes which are available for calcium, zinc, magnesium, and iron...
  32. Geagea M, Stille P, Gauthier Lafaye F, Millet M. Tracing of industrial aerosol sources in an urban environment using Pb, Sr, and Nd isotopes. Environ Sci Technol. 2008;42:692-8 pubmed
    ..The traffic contribution can only be estimated with help of Nd isotopes. Therefore the clear identification of different pollutant sources in the urban environment is only possible by ..
  33. Soto Jimenez M, Paez Osuna F, Scelfo G, Hibdon S, Franks R, Aggarawl J, et al. Lead pollution in subtropical ecosystems on the SE Gulf of California Coast: a study of concentrations and isotopic composition. Mar Environ Res. 2008;66:451-8 pubmed publisher
    ..Statistical software IsoSource results revealed that the Pb contained in environmental matrices and biomonitors is mostly derived from gasoline (20-90%) and US emissions (10-40%)...
  34. Gulson B. Stable lead isotopes in environmental health with emphasis on human investigations. Sci Total Environ. 2008;400:75-92 pubmed publisher
    There has been widespread use of stable lead isotopes in the earth sciences for more than 40 years focussed on the origin and age of rocks and minerals with lesser application in environmental investigations where the emphasis has been ..
  35. Sperling E, Bunner A, Sykes M, Williamson J. Quantitative analysis of isotope distributions in proteomic mass spectrometry using least-squares Fourier transform convolution. Anal Chem. 2008;80:4906-17 pubmed publisher
    ..The least-squares Fourier transform convolution approach can be applied to many types of quantitative proteomic data, including data from stable isotope labeling by amino acids in cell culture and pulse labeling experiments...
  36. Gulson B, Korsch M, Dickson B, Cohen D, Mizon K, Davis J. Comparison of lead isotopes with source apportionment models, including SOM, for air particulates. Sci Total Environ. 2007;381:169-79 pubmed
    We have measured high precision lead isotopes in PM(2...
  37. Glorennec P, Peyr C, Poupon J, Oulhote Y, Le Bot B. Identifying sources of lead exposure for children, with lead concentrations and isotope ratios. J Occup Environ Hyg. 2010;7:253-60 pubmed publisher
    ..However, systematic use should be supported by cost-effectiveness analysis on a larger and more representative population of elevated BLL...
  38. Kanaan N, Ferrer S, Martí S, Garcia Viloca M, Kohen A, Moliner V. Temperature dependence of the kinetic isotope effects in thymidylate synthase. A theoretical study. J Am Chem Soc. 2011;133:6692-702 pubmed publisher
    ..All these terms contribute to the observed temperature independent KIEs in thymidylate synthase...
  39. Ings N, Hildrew A, Grey J. Gardening by the psychomyiid caddisfly Tinodes waeneri: evidence from stable isotopes. Oecologia. 2010;163:127-39 pubmed publisher
    ..Nevertheless, T. waeneri galleries do act as a fertilised garden. 'Gardening' appears to be widespread in this species, and may affect productivity and patterns of nitrogen retention within the stony littoral of lakes...
  40. Buchachenko A, Kouznetsov D, Breslavskaya N, Orlova M. Magnesium isotope effects in enzymatic phosphorylation. J Phys Chem B. 2008;112:2548-56 pubmed publisher
    ..Similar effects have been also found for the pyruvate kinase. Magnetic field dependence of enzymatic phosphorylation is in agreement with suggested ion-radical mechanism...
  41. Cerling T, Wittemyer G, Ehleringer J, Remien C, Douglas Hamilton I. History of Animals using Isotope Records (HAIR): a 6-year dietary history of one family of African elephants. Proc Natl Acad Sci U S A. 2009;106:8093-100 pubmed publisher
  42. Moore J, Semmens B. Incorporating uncertainty and prior information into stable isotope mixing models. Ecol Lett. 2008;11:470-80 pubmed publisher
    Stable isotopes are a powerful tool for ecologists, often used to assess contributions of different sources to a mixture (e.g. prey to a consumer). Mixing models use stable isotope data to estimate the contribution of sources to a mixture...
  43. Elschot M, Nijsen J, Dam A, de Jong H. Quantitative evaluation of scintillation camera imaging characteristics of isotopes used in liver radioembolization. PLoS ONE. 2011;6:e26174 pubmed publisher
    ..The aim of this study is to quantitatively evaluate and compare the imaging characteristics of these three isotopes, in order that imaging protocols can be optimized and RE studies with varying isotopes can be compared.
  44. del Rio C, Wolf N, Carleton S, Gannes L. Isotopic ecology ten years after a call for more laboratory experiments. Biol Rev Camb Philos Soc. 2009;84:91-111 pubmed publisher
    About 10 years ago, reviews of the use of stable isotopes in animal ecology predicted explosive growth in this field and called for laboratory experiments to provide a mechanistic foundation to this growth...
  45. Cerling T, Ayliffe L, Dearing M, Ehleringer J, Passey B, Podlesak D, et al. Determining biological tissue turnover using stable isotopes: the reaction progress variable. Oecologia. 2007;151:175-89 pubmed
    ..Previous growth models have been for exponential growth; the approach here can be used for several different growth models...
  46. Jackson A, Inger R, Bearhop S, Parnell A. Erroneous behaviour of MixSIR, a recently published Bayesian isotope mixing model: a discussion of Moore & Semmens (2008). Ecol Lett. 2009;12:E1-5 pubmed publisher
    ..Moreover, MixSIR uses a formulation for a prior distribution that results in an opaque and unintuitive covariance structure...
  47. Parra Robles J, Ajraoui S, Deppe M, Parnell S, Wild J. Experimental investigation and numerical simulation of 3He gas diffusion in simple geometries: implications for analytical models of 3He MR lung morphometry. J Magn Reson. 2010;204:228-38 pubmed publisher
    ..The results presented here demonstrate that physical assumptions of the cylinder model are not valid for large diffusion gradient strengths (above approximately 15 mT/m), which are commonly used for (3)He ADC measurements in human lungs...
  48. Tsuji Y, Suzuki N, T Suzuki K, Ogra Y. Selenium metabolism in rats with long-term ingestion of Se-methylselenocysteine using enriched stable isotopes. J Toxicol Sci. 2009;34:191-200 pubmed
    ..the metabolism of MeSeCys labeled with an Se isotope, 82Se, in rats depleted of endogenous natural abundance isotopes with another Se isotope, 78Se, was traced for 21 days when MeSeCys was continuously and perorally ingested at a ..
  49. Semmens B, Ward E, Moore J, Darimont C. Quantifying inter- and intra-population niche variability using hierarchical bayesian stable isotope mixing models. PLoS ONE. 2009;4:e6187 pubmed publisher
  50. Hartman G, Danin A. Isotopic values of plants in relation to water availability in the Eastern Mediterranean region. Oecologia. 2010;162:837-52 pubmed publisher
    ..From these results it can be concluded that water availability is the primary factor controlling C and N isotope variability in plant communities in the Eastern Mediterranean...
  51. Jackson A, Inger R, Parnell A, Bearhop S. Comparing isotopic niche widths among and within communities: SIBER - Stable Isotope Bayesian Ellipses in R. J Anim Ecol. 2011;80:595-602 pubmed publisher
    ..The computational code to calculate the new metrics is implemented in the free-to-download package Stable Isotope Analysis for the R statistical environment...
  52. Shiel A, Weis D, Orians K. Evaluation of zinc, cadmium and lead isotope fractionation during smelting and refining. Sci Total Environ. 2010;408:2357-68 pubmed publisher
    ..C., Canada. Significant fractionation of Zn and Cd isotopes during processing of ZnS and PbS ore concentrates is demonstrated by the total variation in delta(66/64)Zn and ..
  53. Parnell A, Inger R, Bearhop S, Jackson A. Source partitioning using stable isotopes: coping with too much variation. PLoS ONE. 2010;5:e9672 pubmed publisher
    ..Key to much of this work is the use of mixing models to estimate the proportion of sources contributing to a mixture such as in diet estimation...