sulfur hexafluoride

Summary

Summary: Sulfur hexafluoride. An inert gas used mainly as a test gas in respiratory physiology. Other uses include its injection in vitreoretinal surgery to restore the vitreous chamber and as a tracer in monitoring the dispersion and deposition of air pollutants.

Top Publications

  1. Munoz C, Yan T, Wills D, Murray S, Gordon A. Comparison of the sulfur hexafluoride tracer and respiration chamber techniques for estimating methane emissions and correction for rectum methane output from dairy cows. J Dairy Sci. 2012;95:3139-48 pubmed publisher
    The objectives of the present study were to compare the sulfur hexafluoride (SF?) and respiration chamber techniques for measuring methane (CH?) emissions from dairy cows and to determine the proportion of CH? that is released through ..
  2. Wu W, Liu C, Chen C, Wang N, Chen K, Chen T, et al. Efficient vitreolysis by combining plasmin and sulfur hexafluoride injection in a preclinical study in rabbit eyes. Mol Vis. 2012;18:2361-70 pubmed
    To investigate the efficacy of plasmin and sulfur hexafluoride (SF(6)) on the vitreoretinal junction, as well as the long-term safety in the eye and effect on the recipient's general health after application in the eye.
  3. Zhang X, Zhang J, Jia Y, Xiao P, Tang J. TiO2 nanotube array sensor for detecting the SF6 decomposition product SO2. Sensors (Basel). 2012;12:3302-13 pubmed publisher
  4. Li C, Wang W, Ding H, Huang B, Cao J, Mao F, et al. Value of contrast-enhanced sonography in the diagnosis of peripheral intrahepatic cholangiocarcinoma. J Clin Ultrasound. 2011;39:447-53 pubmed publisher
    ..To illustrate contrast-enhanced harmonic ultrasonography (CEUS) findings of peripheral intrahepatic cholangiocarcinoma (PICC) and to assess the usefulness of CEUS in the diagnosis of this disease...
  5. Rahman R, Madgula I, Khan K. Outcomes of sulfur hexafluoride (SF6) versus perfluoroethane (C2F6) gas tamponade for non-posturing macular-hole surgery. Br J Ophthalmol. 2012;96:185-8 pubmed publisher
    To compare the outcomes of non-posturing macular-hole surgery using sulfur hexafluoride (SF(6)) gas versus perfluoroethane (C(2)F(6)) for idiopathic macular hole repair. Design Interventional, comparative cohort study.
  6. Kusuhara S, Ooto S, Kimura D, Itoi K, Mukuno H, Miyamoto N, et al. Intraocular gas dynamics after 20-gauge and 23-gauge vitrectomy with sulfur hexafluoride gas tamponade. Retina. 2011;31:250-6 pubmed publisher
    ..The purpose of this study was to evaluate the intraocular gas dynamics after 23-gauge transconjunctival sutureless vitrectomy (TSV) as compared with 20-gauge pars plana vitrectomy (PPV)...
  7. Piscaglia F, Bolondi L. The safety of Sonovue in abdominal applications: retrospective analysis of 23188 investigations. Ultrasound Med Biol. 2006;32:1369-75 pubmed
  8. Marret H, Brewer M, Giraudeau B, Tranquart F, Satterfield W. Assessment of cyclic changes of microvessels in ovine ovaries using Sonovue contrast-enhanced ultrasound. Ultrasound Med Biol. 2006;32:163-9 pubmed
    ..Thus, using these parameters in premenopausal women will allow more accurate detection of vascular modifications that may be associated with ovarian cancer...
  9. Hohmann J, Loddenkemper C, Albrecht T. Assessment of a biliary hamartoma with contrast-enhanced sonography using two different contrast agents. Ultraschall Med. 2009;30:185-8 pubmed publisher
    ..Therefore, while using SonoVue, such a misinterpretation of these very common but in most cases very small and not detectable lesions seems unlikely...

More Information

Publications62

  1. Mura M, Tan S, de Smet M. Use of 25-gauge vitrectomy in the management of primary rhegmatogenous retinal detachment. Retina. 2009;29:1299-1304 pubmed publisher
    ..To evaluate the anatomical and functional results of 25-gauge transconjuctival vitrectomy in the management of primary rhegmatogenous retinal detachment (RRD)...
  2. Greis C. Technology overview: SonoVue (Bracco, Milan). Eur Radiol. 2004;14 Suppl 8:P11-5 pubmed
  3. Aurora P, Gustafsson P, Bush A, Lindblad A, Oliver C, Wallis C, et al. Multiple breath inert gas washout as a measure of ventilation distribution in children with cystic fibrosis. Thorax. 2004;59:1068-73 pubmed
  4. Nicolau C, Bru C. Focal liver lesions: evaluation with contrast-enhanced ultrasonography. Abdom Imaging. 2004;29:348-59 pubmed
  5. Malm S, Frigstad S, Sagberg E, Larsson H, Skjaerpe T. Accurate and reproducible measurement of left ventricular volume and ejection fraction by contrast echocardiography: a comparison with magnetic resonance imaging. J Am Coll Cardiol. 2004;44:1030-5 pubmed
    ..We evaluated the accuracy and reproducibility of contrast echocardiography versus tissue harmonic imaging for measurements of left ventricular (LV) volumes and ejection fraction (EF) compared to magnetic resonance imaging (MRI)...
  6. Piscaglia F, Lencioni R, Sagrini E, Pina C, Cioni D, Vidili G, et al. Characterization of focal liver lesions with contrast-enhanced ultrasound. Ultrasound Med Biol. 2010;36:531-50 pubmed publisher
  7. Dijkmans P, Juffermans L, Van Dijk J, Musters R, Spreeuwenberg -, Kamp O. Safety and feasibility of real time adenosine myocardial contrast echocardiography with emphasis on induction of arrhythmias: a study in healthy volunteers and patients with stable coronary artery disease. Echocardiography. 2009;26:807-14 pubmed publisher
    ..The aim of the study was to assess the occurrence of arrhythmias during real time adenosine MCE in healthy volunteers and patients with stable coronary artery disease (CAD)...
  8. Correas J, Tranquart F, Claudon M. [Guidelines for contrast enhanced ultrasound (CEUS)--update 2008]. J Radiol. 2009;90:123-38; quiz 139-40 pubmed
    ..It is also useful for the study of pancreatic masses visible at ultrasound in order to improve lesion visualization and characterization (adenocarcinoma and neuro-endocrine tumors), as well as for vascular staging...
  9. D Onofrio M, Vecchiato F, Cantisani V, Barbi E, Passamonti M, Ricci P, et al. Intrahepatic peripheral cholangiocarcinoma (IPCC): comparison between perfusion ultrasound and CT imaging. Radiol Med. 2008;113:76-86 pubmed publisher
    ..This study was done to compare the perfusion patterns of intrahepatic peripheral cholangiocarcinoma (IPCC) on contrast-enhanced ultrasound (CEUS) and dynamic computed tomography (CT)...
  10. Krenning B, Kirschbaum S, Soliman O, Nemes A, van Geuns R, Vletter W, et al. Comparison of contrast agent-enhanced versus non-contrast agent-enhanced real-time three-dimensional echocardiography for analysis of left ventricular systolic function. Am J Cardiol. 2007;100:1485-9 pubmed
    ..In conclusion, contrast agent-enhanced RT3DE is more accurate in assessment of LV function as evidenced by better correlation and narrower limits of agreement compared with MRI, as well as lower intra- and interobserver variabilities...
  11. Geyer O, Segev E, Steinberg J, Buckman G. Stabilization of post-trabeculectomy flat anterior chamber with Healon and sulfur hexafluoride. J Cataract Refract Surg. 2003;29:2026-8 pubmed
    ..When separate attempts to reform the anterior chamber by intracameral injection of sulfur hexafluoride (SF(6)) and sodium hyaluronate 1...
  12. Colyer M, Barazi M, Von Fricken M. Retrospective comparison of 25-gauge transconjunctival sutureless vitrectomy to 20-gauge vitrectomy for the repair of pseudophakic primary inferior rhegmatogenous retinal detachment. Retina. 2010;30:1678-84 pubmed publisher
    ..To compare anatomical and functional outcomes of 25-gauge transconjunctival sutureless pars plana vitrectomy (PPV) to standard 20-gauge 3-port PPV for the treatment of pseudophakic rhegmatogenous retinal detachments with inferior breaks...
  13. Panda A, Aggarwal A, Madhavi P, Wagh V, Dada T, Kumar A, et al. Management of acute corneal hydrops secondary to keratoconus with intracameral injection of sulfur hexafluoride (SF6). Cornea. 2007;26:1067-9 pubmed
    To report the use of sulfur hexafluoride (SF6) gas in the management of corneal edema caused by acute corneal hydrops secondary to keratoconus.
  14. Bartolotta T, Midiri M, Galia M, Rollandi G, Cademartiri F, Lagalla R, et al. Characterization of benign hepatic tumors arising in fatty liver with SonoVue and pulse inversion US. Abdom Imaging. 2007;32:84-91 pubmed
    ..We describe the spectrum of contrast-enhancement patterns of benign hepatic tumors arising in fatty liver on contrast-enhanced ultrasound (US)...
  15. Testa A, Ferrandina G, Fruscella E, Van Holsbeke C, Ferrazzi E, Leone F, et al. The use of contrasted transvaginal sonography in the diagnosis of gynecologic diseases: a preliminary study. J Ultrasound Med. 2005;24:1267-78 pubmed
  16. Nicolau C, Vilana R, Catalá V, Bianchi L, Gilabert R, Garcia A, et al. Importance of evaluating all vascular phases on contrast-enhanced sonography in the differentiation of benign from malignant focal liver lesions. AJR Am J Roentgenol. 2006;186:158-67 pubmed
    ..Our objective was to evaluate the accuracy of a blood-pool sonographic contrast agent in the late phase compared with the three vascular phases for differentiation between benign and malignant focal liver lesions...
  17. Zviniene K, Zaboriene I, Basevicius A, Jurkiene N, Barauskas G, Pundzius J. Comparative diagnostic value of contrast-enhanced ultrasonography, computed tomography, and magnetic resonance imaging in diagnosis of hepatic hemangiomas. Medicina (Kaunas). 2010;46:329-35 pubmed
    ..1%. Intravenous contrast-enhanced US is more specific than intravenous contrast-enhanced CT in the diagnosis of hepatic hemangioma (P=0.0005) and has a higher positive prognostic value (P=0.001). ..
  18. Robinson P, Goldman M, Gustafsson P. Inert gas washout: theoretical background and clinical utility in respiratory disease. Respiration. 2009;78:339-55 pubmed publisher
  19. Carvounis P, Kopel A, Kuhl D, Heffez J, Pepple K, Holz E. 25-gauge vitrectomy using sulfur hexafluoride and no prone positioning for repair of macular holes. Retina. 2008;28:1188-92 pubmed publisher
    To report on the outcomes of 25-gauge pars plana vitrectomy using sulfur hexafluoride and no prone positioning for repair of macular holes.
  20. Stang A, Keles H, Hentschke S, von Seydewitz C, Dahlke J, Malzfeldt E, et al. Differentiation of benign from malignant focal splenic lesions using sulfur hexafluoride-filled microbubble contrast-enhanced pulse-inversion sonography. AJR Am J Roentgenol. 2009;193:709-21 pubmed publisher
    The purpose of our study was to evaluate whether sonographic characterization of focal splenic lesions could be improved by using low mechanical index pulse-inversion sonography after sulfur hexafluoride-filled microbubble injection.
  21. Beaton C, Cochlin D, Kumar N. Contrast enhanced ultrasound should be the initial radiological investigation to characterise focal liver lesions. Eur J Surg Oncol. 2010;36:43-6 pubmed publisher
    ..This study aims to determine how effective CEUS is at characterising focal liver lesions and to establish its role in the diagnostic algorithm...
  22. Park S, Seo M. Subhyaloid hemorrhage treated with SF6 gas injection. Ophthalmic Surg Lasers Imaging. 2004;35:335-7 pubmed
    ..Pure sulfur hexafluoride (SF6, 0...
  23. Ascenti G, Zimbaro G, Mazziotti S, Chimenz R, Fede C, Visalli C, et al. Harmonic US imaging of vesicoureteric reflux in children: usefulness of a second generation US contrast agent. Pediatr Radiol. 2004;34:481-7 pubmed
    ..Contrast-enhanced voiding urosonography (VUS) is largely accepted both for the diagnosis and follow-up of vesicoureteric reflux (VUR) in children...
  24. Dietrich C, Mertens J, Braden B, Schuessler G, Ott M, Ignee A. Contrast-enhanced ultrasound of histologically proven liver hemangiomas. Hepatology. 2007;45:1139-45 pubmed
    ..Forty-five (78%) of the hemangiomas showed homogenous centripetal filling within 180 seconds...
  25. Li R, Guo Y, Hua X, He Y, Ding J, Guo A, et al. Characterization of focal liver lesions: comparison of pulse-inversion harmonic contrast-enhanced sonography with contrast-enhanced CT. J Clin Ultrasound. 2007;35:109-17 pubmed
    ..To compare the efficacy of contrast-enhanced pulse-inversion harmonic sonography for the characterization of focal liver lesions with that of contrast-enhanced helical CT...
  26. Mischi M, Jansen A, Korsten H. Identification of cardiovascular dilution systems by contrast ultrasound. Ultrasound Med Biol. 2007;33:439-51 pubmed
    ..88 correlation coefficient with echocardiographic biplane estimates. In conclusion, adding a priori knowledge to the system identification algorithm leads to increased accuracy and robustness of the method for PBV and EF measurements...
  27. Solbiati L, Ierace T, Tonolini M, Cova L. Guidance and control of percutaneous treatments with contrast-enhanced ultrasound. Eur Radiol. 2003;13 Suppl 3:N87-90 pubmed
  28. Catalano O, Sandomenico F, Raso M, Siani A. Low mechanical index contrast-enhanced sonographic findings of pyogenic hepatic abscesses. AJR Am J Roentgenol. 2004;182:447-50 pubmed
    ..We describe the contrast-specific sonographic findings of pyogenic hepatic abscesses...
  29. Vilana R, Forner A, Bianchi L, García Criado A, Rimola J, de Lope C, et al. Intrahepatic peripheral cholangiocarcinoma in cirrhosis patients may display a vascular pattern similar to hepatocellular carcinoma on contrast-enhanced ultrasound. Hepatology. 2010;51:2020-9 pubmed publisher
    ..However, none of these lesions displayed washout on MRI...
  30. Men G, Peyman G, Genaidy M, Kuo P, Ghahramani F, Blake D, et al. The role of recombinant lysine-plasminogen and recombinant urokinase and sulfur hexafluoride combination in inducing posterior vitreous detachment. Retina. 2004;24:199-209 pubmed
    ..determine the optimal method of generating plasmin in vitreous using recombinant lysine-plasminogen and recombinant urokinase and to determine its efficacy in inducing posterior vitreous detachment when combined with sulfur hexafluoride.
  31. Fleischer A, Lyshchik A, Andreotti R, Hwang M, Jones H, Fishman D. Advances in sonographic detection of ovarian cancer: depiction of tumor neovascularity with microbubbles. AJR Am J Roentgenol. 2010;194:343-8 pubmed publisher
  32. Piscaglia F, Venturi A, Mancini M, Giangregorio F, Vidili G, Magnolfi F, et al. Diagnostic features of real-time contrast-enhanced ultrasound in focal nodular hyperplasia of the liver. Ultraschall Med. 2010;31:276-82 pubmed publisher
    ..The aim of the present study was to assess the ultrasound pattern of FNH with special attention to real-time contrast-enhanced ultrasonography (CEUS) appearance and specifically to the timing of perfusion patterns...
  33. Sii F, Lee G, Gole G. Perforated corneal hydrops treated with sulfur hexafluoride (SF6) gas and tissue adhesive. Cornea. 2005;24:503-4 pubmed
    To report a case of a perforated acute hydrops in a mentally retarded patient that was successfully managed with intracameral sulfur hexafluoride gas and cyanoacrylate tissue adhesive.
  34. Vilana R, Bianchi L, Varela M, Nicolau C, Sanchez M, Ayuso C, et al. Is microbubble-enhanced ultrasonography sufficient for assessment of response to percutaneous treatment in patients with early hepatocellular carcinoma?. Eur Radiol. 2006;16:2454-62 pubmed
    ..The 1-month CEUS has a high diagnostic accuracy compared with spiral-CT in the usual assessment of percutaneous treatment response...
  35. Gaibazzi N, Squeri A, Ardissino D, Reverberi C. Safety of contrast flash-replenishment stress echocardiography in 500 patients with a chest pain episode of undetermined origin within the last 5 days. Eur J Echocardiogr. 2009;10:726-32 pubmed publisher
    ..The purpose of the present study was to provide evidence regarding the safety of flash-replenishment contrast dipyridamole-atropine echocardiography (DASE) in such patients...
  36. Pelzer A, Bektic J, Berger A, Pallwein L, Halpern E, Horninger W, et al. Prostate cancer detection in men with prostate specific antigen 4 to 10 ng/ml using a combined approach of contrast enhanced color Doppler targeted and systematic biopsy. J Urol. 2005;173:1926-9 pubmed
    ..We evaluated the impact of a combined approach of contrast enhanced, color Doppler targeted biopsy (CECD) and systematic biopsy (SB) for the PC detection rate in men with prostate specific antigen (PSA) 4.0 to 10 ng/ml...
  37. Kwee R, van den Bosch M, El Ouamari M, Kemps B, Arensman L, van Hillegersberg R, et al. Contrast-enhanced breast ultrasonography reveals an unusual breast tumor in a male patient with gynecomastia. J Ultrasound Med. 2006;25:1347-51 pubmed
  38. Miller D, Riemann C, Foster R, Petersen M. Primary repair of retinal detachment with 25-gauge pars plana vitrectomy. Retina. 2008;28:931-6 pubmed publisher
    ..To evaluate 25-gauge pars plana vitrectomy (PPV) for primary repair of rhegmatogenous retinal detachment (RRD)...
  39. Lai M, Ruby A, Sarrafizadeh R, Urban K, Hassan T, Drenser K, et al. Repair of primary rhegmatogenous retinal detachment using 25-gauge transconjunctival sutureless vitrectomy. Retina. 2008;28:729-34 pubmed publisher
    ..To evaluate the anatomical and visual outcomes of primary rhegmatogenous retinal detachment repairs performed using 25-gauge transconjunctival sutureless vitrectomy...
  40. Alter J, Sennoga C, Lopes D, Eckersley R, Wells D. Microbubble stability is a major determinant of the efficiency of ultrasound and microbubble mediated in vivo gene transfer. Ultrasound Med Biol. 2009;35:976-84 pubmed publisher
    ..These findings emphasize the importance of detailed investigations into the properties of microbubbles to allow the production of a microbubble specifically designed for optimum performance with MBGT...
  41. Nicolau C, Catalá V, Vilana R, Gilabert R, Bianchi L, Sole M, et al. Evaluation of hepatocellular carcinoma using SonoVue, a second generation ultrasound contrast agent: correlation with cellular differentiation. Eur Radiol. 2004;14:1092-9 pubmed
    ..Echogenicity in the portal and late phases correlated with cellular differentiation...
  42. Grainger C, Clarke T, McGinn S, Auldist M, Beauchemin K, Hannah M, et al. Methane emissions from dairy cows measured using the sulfur hexafluoride (SF6) tracer and chamber techniques. J Dairy Sci. 2007;90:2755-66 pubmed
    Our study compared methane (CH4) emissions from lactating dairy cows measured using the sulfur hexafluoride (SF6) tracer and open-circuit respiration chamber techniques. The study was conducted using 16 lactating Holstein-Friesian cows...
  43. Pillow J, Ljungberg H, Hulskamp G, Stocks J. Functional residual capacity measurements in healthy infants: ultrasonic flow meter versus a mass spectrometer. Eur Respir J. 2004;23:763-8 pubmed
    ..7%) and FRCUS (5.2%). The ultrasonic flow meter used in this study provides repeatable measurements of functional residual capacity in spontaneously breathing healthy infants that approximate those obtained during mass spectrometry...
  44. Gustafsson P. Inert gas washout in preschool children. Paediatr Respir Rev. 2005;6:239-45 pubmed
    ..The MBW method may be useful also for screening for several other disorders that affect the peripheral airways in children...
  45. Li R, Zhang X, Hua X, Cai P, Zhong H, Guo Y, et al. Real-time contrast-enhanced ultrasonography of resected and immunohistochemically proven hepatic angiomyolipomas. Abdom Imaging. 2010;35:676-82 pubmed publisher
    ..The purpose of this study was to assess real-time contrast-enhanced ultrasound in patients with hepatic angiomyolipomas with respect to contrast-enhancing kinetics and enhancement patterns...
  46. Solbiati L, Ierace T, Tonolini M, Cova L. Guidance and monitoring of radiofrequency liver tumor ablation with contrast-enhanced ultrasound. Eur J Radiol. 2004;51 Suppl:S19-23 pubmed
    ..1 to 5.9%. Cost-effectiveness and reduction of patients' discomfort related to the need of re-treatment are the two most outstanding advantages of CEUS in this field...
  47. Tranquart F, Correas J, Ladam Marcus V, Manzoni P, Vilgrain V, Aube C, et al. [Real-time contrast-enhanced ultrasound in the evaluation of focal liver lesions: diagnostic efficacy and economical issues from a French multicentric study]. J Radiol. 2009;90:109-22 pubmed
    ..This French multicentric study confirmed the high diagnostic value of CEUS for focal liver lesion characterization and demonstrated a lower economical impact compared to other imaging modalities such as CT and MRI...
  48. Seitz K, Bernatik T, Strobel D, Blank W, Friedrich Rust M, Strunk H, et al. Contrast-enhanced ultrasound (CEUS) for the characterization of focal liver lesions in clinical practice (DEGUM Multicenter Trial): CEUS vs. MRI--a prospective comparison in 269 patients. Ultraschall Med. 2010;31:492-9 pubmed publisher
    ..One important aspect is the comparison of CEUS with magnetic resonance imaging (MRI)...
  49. Nyman H, Kristensen A, Kjelgaard Hansen M, McEvoy F. Contrast-enhanced ultrasonography in normal canine liver. Evaluation of imaging and safety parameters. Vet Radiol Ultrasound. 2005;46:243-50 pubmed
    ..When considering normal values, the use of anesthetic drugs has to be considered...
  50. Quaia E, Calliada F, Bertolotto M, Rossi S, Garioni L, Rosa L, et al. Characterization of focal liver lesions with contrast-specific US modes and a sulfur hexafluoride-filled microbubble contrast agent: diagnostic performance and confidence. Radiology. 2004;232:420-30 pubmed
    ..of solid focal liver lesions could be improved by using ultrasonographic (US) contrast-specific modes after sulfur hexafluoride-filled microbubble contrast agent injection, as compared with lesion characterization achieved with ..
  51. Wang Y, Yu X, Tang J, Li H, Liu L, Gao Y. Solitary necrotic nodule of the liver: contrast-enhanced sonography. J Clin Ultrasound. 2007;35:177-81 pubmed
    ..To report contrast-enhanced sonography (CEUS) for solitary necrotic nodule (SNN) of the liver and to assess its clinical value...
  52. von Herbay A, Westendorff J, Gregor M. Contrast-enhanced ultrasound with SonoVue: differentiation between benign and malignant focal liver lesions in 317 patients. J Clin Ultrasound. 2010;38:1-9 pubmed publisher
    ..The aim of the study was to investigate the ability of contrast-enhanced sonography (CEUS) with the contrast agent SonoVue to differentiate between benign and malignant focal liver lesions...
  53. Tarantino L, Francica G, Sordelli I, Esposito F, Giorgio A, Sorrentino P, et al. Diagnosis of benign and malignant portal vein thrombosis in cirrhotic patients with hepatocellular carcinoma: color Doppler US, contrast-enhanced US, and fine-needle biopsy. Abdom Imaging. 2006;31:537-44 pubmed
    ..We assessed the role of contrast-enhanced ultrasound (CEUS) in the differential diagnosis between benign and malignant portal vein thrombosis in patients who had cirrhosis with hepatocellular carcinoma (HCC)...