singlet oxygen

Summary

Summary: An excited state of molecular oxygen generated photochemically or chemically. Singlet oxygen reacts with a variety of biological molecules such as NUCLEIC ACIDS; PROTEINS; and LIPIDS; causing oxidative damages.

Top Publications

  1. Mallidi S, Anbil S, LEE S, Manstein D, Elrington S, Kositratna G, et al. Photosensitizer fluorescence and singlet oxygen luminescence as dosimetric predictors of topical 5-aminolevulinic acid photodynamic therapy induced clinical erythema. J Biomed Opt. 2014;19:028001 pubmed publisher
    ..g., minimally aggregated and monomeric), we suggest that singlet oxygen luminescence (SOL) indicates only the active PS component responsible for the PDT...
  2. Qi Y, Garren E, Shu X, Tsien R, Jin Y. Photo-inducible cell ablation in Caenorhabditis elegans using the genetically encoded singlet oxygen generating protein miniSOG. Proc Natl Acad Sci U S A. 2012;109:7499-504 pubmed publisher
    ..light-inducible and tissue-selective cell ablation using a genetically encoded photosensitizer, miniSOG (mini singlet oxygen generator)...
  3. Han S, Sakuraba Y, Koh H, Paek N. Leaf variegation in the rice zebra2 mutant is caused by photoperiodic accumulation of tetra-cis-lycopene and singlet oxygen. Mol Cells. 2012;33:87-97 pubmed publisher
    ..In addition, three types of reactive oxygen species (ROS; superoxide [O??], hydrogen peroxide [H?O?], and singlet oxygen [¹O?]) accumulated to high levels in z2 mutants grown under short-day conditions (SD; alternate 10-h light/14-..
  4. Gemmell N, McCarthy A, Liu B, Tanner M, Dorenbos S, Zwiller V, et al. Singlet oxygen luminescence detection with a fiber-coupled superconducting nanowire single-photon detector. Opt Express. 2013;21:5005-13 pubmed publisher
    Direct monitoring of singlet oxygen (¹O?) luminescence is a particularly challenging infrared photodetection problem. ¹O?, an excited state of the oxygen molecule, is a crucial intermediate in many biological processes...
  5. Jarvi M, Patterson M, Wilson B. Insights into photodynamic therapy dosimetry: simultaneous singlet oxygen luminescence and photosensitizer photobleaching measurements. Biophys J. 2012;102:661-71 pubmed publisher
    Photodynamic therapy (PDT) is generally based on the generation of highly reactive singlet oxygen ((1)O(2)) through interactions of photosensitizer, light, and oxygen ((3)O(2))...
  6. Glaeser J, Nuss A, Berghoff B, Klug G. Singlet oxygen stress in microorganisms. Adv Microb Physiol. 2011;58:141-73 pubmed publisher
    b>Singlet oxygen is the primary agent of photooxidative stress in microorganisms...
  7. Signorelli S, Arellano J, Melø T, Borsani O, Monza J. Proline does not quench singlet oxygen: evidence to reconsider its protective role in plants. Plant Physiol Biochem. 2013;64:80-3 pubmed publisher
    ..One type of ROS aimed to be quenched by proline is singlet oxygen ((1)O(2))-molecular oxygen in its lowest energy electronically excited state-constitutively generated in ..
  8. Li H, Melø T, Arellano J, Razi Naqvi K. Temporal profile of the singlet oxygen emission endogenously produced by photosystem II reaction centre in an aqueous buffer. Photosynth Res. 2012;112:75-9 pubmed publisher
    The temporal profile of the phosphorescence of singlet oxygen endogenously photosensitized by photosystem II (PSII) reaction centre (RC) in an aqueous buffer has been recorded using laser excitation and a near infrared photomultiplier ..
  9. Osakada Y, Kawai K, Tachikawa T, Fujitsuka M, Tainaka K, Tero Kubota S, et al. Generation of singlet oxygen during photosensitized one-electron oxidation of DNA. Chemistry. 2012;18:1060-3 pubmed publisher

More Information

Publications62

  1. Gallavardin T, Armagnat C, Maury O, Baldeck P, Lindgren M, Monnereau C, et al. An improved singlet oxygen sensitizer with two-photon absorption and emission in the biological transparency window as a result of ground state symmetry-breaking. Chem Commun (Camb). 2012;48:1689-91 pubmed publisher
    ..featuring a diyne bridge that connects two dibromobenzene moieties shows a much improved two-photon singlet oxygen generation ability in the biological transparency window compared to a related and relevant literature ..
  2. Yadav D, Pospisil P. Evidence on the formation of singlet oxygen in the donor side photoinhibition of photosystem II: EPR spin-trapping study. PLoS ONE. 2012;7:e45883 pubmed publisher
    When photosystem II (PSII) is exposed to excess light, singlet oxygen ((1)O(2)) formed by the interaction of molecular oxygen with triplet chlorophyll...
  3. Sinha R, Komenda J, Knoppová J, Sedlárová M, Pospisil P. Small CAB-like proteins prevent formation of singlet oxygen in the damaged photosystem II complex of the cyanobacterium Synechocystis sp. PCC 6803. Plant Cell Environ. 2012;35:806-18 pubmed publisher
    ..In this study, the effect of SCPs on the PSII-specific light-induced damage and generation of singlet oxygen ((1)O(2)) was assessed in the strains of the cyanobacterium Synechocystis sp...
  4. Bäumler W, Regensburger J, Knak A, Felgenträger A, Maisch T. UVA and endogenous photosensitizers--the detection of singlet oxygen by its luminescence. Photochem Photobiol Sci. 2012;11:107-17 pubmed publisher
    ..irradiation in endogenous chromophores frequently leads to the generation of reactive oxygen species such as singlet oxygen ((1)O(2)). (1)O(2) is an important biochemical intermediate in multiple biological processes...
  5. Nishinaka Y, Arai T, Adachi S, Takaori Kondo A, Yamashita K. Singlet oxygen is essential for neutrophil extracellular trap formation. Biochem Biophys Res Commun. 2011;413:75-9 pubmed publisher
    ..However, the active species were not identified. In this study, we discovered that singlet oxygen, one of the ROS, mediated Nox-dependent NET formation upon stimulation with phorbol myristate acetate...
  6. Weston M, Patterson M. Calculation of singlet oxygen dose using explicit and implicit dose metrics during benzoporphyrin derivative monoacid ring A (BPD-MA)-PDT in vitro and correlation with MLL cell survival. Photochem Photobiol. 2011;87:1129-37 pubmed publisher
    ..the total amount of oxygen consumed by PDT per unit volume, which is assumed to be equivalent to the amount of singlet oxygen that reacted...
  7. Rehman A, Cser K, Sass L, Vass I. Characterization of singlet oxygen production and its involvement in photodamage of Photosystem II in the cyanobacterium Synechocystis PCC 6803 by histidine-mediated chemical trapping. Biochim Biophys Acta. 2013;1827:689-98 pubmed publisher
    b>Singlet oxygen production in intact cells of the cynobacterium Synechocystis 6803 was studied using chemical trapping by histidine, which leads to O2 uptake during illumination...
  8. Berghoff B, Konzer A, Mank N, Looso M, Rische T, Förstner K, et al. Integrative "omics"-approach discovers dynamic and regulatory features of bacterial stress responses. PLoS Genet. 2013;9:e1003576 pubmed publisher
    ..In the phototrophic bacterium Rhodobacter sphaeroides the response to singlet oxygen is initiated by alternative sigma factors...
  9. Awuah S, Polreis J, Biradar V, You Y. Singlet oxygen generation by novel NIR BODIPY dyes. Org Lett. 2011;13:3884-7 pubmed publisher
    Five novel near-infrared BODIPY dyes were prepared for improved singlet oxygen generation using thiophene and bromine. Theoretical, optical, photostable, and singlet oxygen generation characteristics of these dyes were assessed...
  10. de Lucas N, Correa R, Garden S, Santos G, Rodrigues R, Carvalho C, et al. Singlet oxygen production by pyrano and furano 1,4-naphthoquinones in non-aqueous medium. Photochem Photobiol Sci. 2012;11:1201-9 pubmed publisher
    ..A systematic study on the efficiency of singlet oxygen generation by these 1,4-naphthoquinones is presented, and values larger than 0.7 were found in every case...
  11. Muthukrishnan N, Johnson G, Erazo Oliveras A, Pellois J. Synergy between cell-penetrating peptides and singlet oxygen generators leads to efficient photolysis of membranes. Photochem Photobiol. 2013;89:625-30 pubmed publisher
    ..peptides TAT and R9 labeled with tetramethylrhodamine photolyze red blood cells by promoting the formation of singlet oxygen in the vicinity of the cells' membranes...
  12. Ramel F, Ksas B, Akkari E, Mialoundama A, Monnet F, Krieger Liszkay A, et al. Light-induced acclimation of the Arabidopsis chlorina1 mutant to singlet oxygen. Plant Cell. 2013;25:1445-62 pubmed publisher
    b>Singlet oxygen (¹O?) is a reactive oxygen species that can function as a stress signal in plant leaves leading to programmed cell death. In microalgae, ¹O?-induced transcriptomic changes result in acclimation to ¹O?...
  13. Kim C, Apel K. Singlet oxygen-mediated signaling in plants: moving from flu to wild type reveals an increasing complexity. Photosynth Res. 2013;116:455-64 pubmed publisher
    b>Singlet oxygen ((1)O2)-mediated signaling has been established in the conditional fluorescent (flu) mutant of Arabidopsis...
  14. Liu B, Farrell T, Patterson M. Comparison of photodynamic therapy with different excitation wavelengths using a dynamic model of aminolevulinic acid-photodynamic therapy of human skin. J Biomed Opt. 2012;17:088001-1 pubmed publisher
    ..depth-dependent distributions of PDT components including ground-state oxygen, sensitizer, and reacted singlet oxygen for different treatment wavelengths (405, 523, and 633 nm) using a numerical model of ALA-PDT of human skin...
  15. Ramel F, Birtić S, Cuiné S, Triantaphylidès C, Ravanat J, Havaux M. Chemical quenching of singlet oxygen by carotenoids in plants. Plant Physiol. 2012;158:1267-78 pubmed publisher
    Carotenoids are considered to be the first line of defense of plants against singlet oxygen ((1)O(2)) toxicity because of their capacity to quench (1)O(2) as well as triplet chlorophylls through a physical mechanism involving transfer of ..
  16. Liu B, Farrell T, Patterson M. Comparison of noninvasive photodynamic therapy dosimetry methods using a dynamic model of ALA-PDT of human skin. Phys Med Biol. 2012;57:825-41 pubmed publisher
    ..The AFBM was less sensitive to treatment conditions but CSOL demonstrated the best overall performance...
  17. Massari J, Tokikawa R, Medinas D, Angeli J, Di Mascio P, Assunção N, et al. Generation of singlet oxygen by the glyoxal-peroxynitrite system. J Am Chem Soc. 2011;133:20761-8 pubmed publisher
    ..71 mT and a(H) = 0.14 mT). The novelty here is the detection of singlet oxygen ((1)?(g)) monomol light emission at 1270 nm during the reaction, probably formed by subsequent dioxygen ..
  18. Frühwirth S, Teich K, Klug G. Effects of the cryptochrome CryB from Rhodobacter sphaeroides on global gene expression in the dark or blue light or in the presence of singlet oxygen. PLoS ONE. 2012;7:e33791 pubmed publisher
    ..it does not only affect gene expression in response to blue light illumination but also in response to singlet oxygen stress conditions...
  19. Fischer B, Ledford H, Wakao S, Huang S, Casero D, Pellegrini M, et al. SINGLET OXYGEN RESISTANT 1 links reactive electrophile signaling to singlet oxygen acclimation in Chlamydomonas reinhardtii. Proc Natl Acad Sci U S A. 2012;109:E1302-11 pubmed publisher
    Acclimation of Chlamydomonas reinhardtii cells to low levels of singlet oxygen, produced either by photoreactive chemicals or high light treatment, induces a specific genetic response that strongly increases the tolerance of the algae to ..
  20. Rolim J, de Melo M, Guedes S, Albuquerque Filho F, de Souza J, Nogueira N, et al. The antimicrobial activity of photodynamic therapy against Streptococcus mutans using different photosensitizers. J Photochem Photobiol B. 2012;106:40-6 pubmed publisher
    Several photosensitizers have been used against oral bacteria without standardization. Singlet oxygen ((1)O(2)) is an aggressive chemical species that can kill cells through apoptosis or necrosis.
  21. Metz S, J ger A, Klug G. Role of a short light, oxygen, voltage (LOV) domain protein in blue light- and singlet oxygen-dependent gene regulation in Rhodobacter sphaeroides. Microbiology. 2012;158:368-79 pubmed publisher
    ..RsLOV affects not only blue light-dependent gene expression but also redox-dependent regulation...
  22. Fischer B, Hideg E, Krieger Liszkay A. Production, detection, and signaling of singlet oxygen in photosynthetic organisms. Antioxid Redox Signal. 2013;18:2145-62 pubmed publisher
    In photosynthetic organisms, excited chlorophylls (Chl) can stimulate the formation of singlet oxygen ((1)O(2)), a highly toxic molecule that acts in addition to its damaging nature as an important signaling molecule...
  23. Ragàs X, He X, Agut M, Roxo Rosa M, Gonsalves A, Serra A, et al. Singlet oxygen in antimicrobial photodynamic therapy: photosensitizer-dependent production and decay in E. coli. Molecules. 2013;18:2712-25 pubmed publisher
    ..in physical and photochemical properties can lead to different localization patterns as well as differences in singlet oxygen production and decay when the photosensitizers are taken up by bacterial cells...
  24. Suzukawa A, Vieira A, Winnischofer S, Scalfo A, Di Mascio P, Ferreira A, et al. Novel properties of melanins include promotion of DNA strand breaks, impairment of repair, and reduced ability to damage DNA after quenching of singlet oxygen. Free Radic Biol Med. 2012;52:1945-53 pubmed publisher
    ..These results may also be applied to the development of protocols to sensitize melanoma cells to PDT...
  25. Silva E, Schaberle F, Monteiro C, Dabrowski J, Arnaut L. The challenging combination of intense fluorescence and high singlet oxygen quantum yield in photostable chlorins--a contribution to theranostics. Photochem Photobiol Sci. 2013;12:1187-92 pubmed publisher
    High fluorescence quantum yields, high singlet oxygen quantum yields and intense absorptions in the phototherapeutic window are fundamental properties for compounds intended for fluorescence diagnosis and photodynamic therapy...
  26. Ruiz González R, Cortajarena A, Mejias S, Agut M, Nonell S, Flors C. Singlet oxygen generation by the genetically encoded tag miniSOG. J Am Chem Soc. 2013;135:9564-7 pubmed publisher
    ..miniSOG is expected to revolutionize correlative light- and electron microscopy due to its ability to produce singlet oxygen upon light irradiation. The quantum yield of this process was reported as ?? = 0.47 ± 0...
  27. Chen F, Zhang S, Bu W, Chen Y, Xiao Q, Liu J, et al. A uniform sub-50 nm-sized magnetic/upconversion fluorescent bimodal imaging agent capable of generating singlet oxygen by using a 980 nm laser. Chemistry. 2012;18:7082-90 pubmed publisher
    ..We envision that such a PDT drug will become a potential theranostic nanomedicine for future near-infrared laser-triggered photodynamic therapy and simultaneous magnetic/optical bimodal imaging...
  28. Butzloff S, Groves M, Wrenger C, Müller I. Cytometric quantification of singlet oxygen in the human malaria parasite Plasmodium falciparum. Cytometry A. 2012;81:698-703 pubmed publisher
    ..oxygen species (ROS) such as hydrogen peroxide, hydroxyl radical, superoxide anion, and highly reactive singlet oxygen ((1)O(2))...
  29. Böhm F, Edge R, Truscott T. Interactions of dietary carotenoids with singlet oxygen (1O2) and free radicals: potential effects for human health. Acta Biochim Pol. 2012;59:27-30 pubmed
    ..The protection mechanisms involve both quenching of singlet oxygen and of damaging free radicals...
  30. Idris N, Gnanasammandhan M, Zhang J, Ho P, Mahendran R, Zhang Y. In vivo photodynamic therapy using upconversion nanoparticles as remote-controlled nanotransducers. Nat Med. 2012;18:1580-5 pubmed publisher
    ..approach compared to approaches using a single photosensitizer, as determined by enhanced generation of singlet oxygen and reduced cell viability...
  31. Mitrica R, Dumitru I, Ruta L, Ofiteru A, Farcasanu I. The dual action of epigallocatechin gallate (EGCG), the main constituent of green tea, against the deleterious effects of visible light and singlet oxygen-generating conditions as seen in yeast cells. Molecules. 2012;17:10355-69 pubmed publisher
    ..Similar synergistic effects could be observed under singlet oxygen-generating conditions, such as light exposure in the presence of photosensitizers or UV-A irradiation, ..
  32. Wang J, Hou Y, Lei W, Zhou Q, Li C, Zhang B, et al. DNA photocleavage by a cationic BODIPY dye through both singlet oxygen and hydroxyl radical: new insight into the photodynamic mechanism of BODIPYs. Chemphyschem. 2012;13:2739-47 pubmed publisher
    ..While one BODIPY dye photocleaves DNA mainly through singlet oxygen, the other photocleaves DNA through both singlet oxygen and hydroxyl radical...
  33. Pedersen B, Sinks L, Breitenbach T, Schack N, Vinogradov S, Ogilby P. Single cell responses to spatially controlled photosensitized production of extracellular singlet oxygen. Photochem Photobiol. 2011;87:1077-91 pubmed publisher
    The response of individual HeLa cells to extracellularly produced singlet oxygen was examined...
  34. Mahendran A, Kopkalli Y, Ghosh G, Ghogare A, Minnis M, Kruft B, et al. A hand-held fiber-optic implement for the site-specific delivery of photosensitizer and singlet oxygen. Photochem Photobiol. 2011;87:1330-7 pubmed publisher
    We have constructed a fiber optic device that internally flows triplet oxygen and externally produces singlet oxygen, causing a reaction at the (Z)-1,2-dialkoxyethene spacer group, freeing a pheophorbide sensitizer upon the fragmentation ..
  35. Regensburger J, Knak A, Maisch T, Landthaler M, Bäumler W. Fatty acids and vitamins generate singlet oxygen under UVB irradiation. Exp Dermatol. 2012;21:135-9 pubmed publisher
    ..In contrast, UVA radiation generates reactive oxygen species such as singlet oxygen, which can initiate a variety of cellular damages and cellular signalling...
  36. Ramel F, Birtić S, Ginies C, Soubigou Taconnat L, Triantaphylidès C, Havaux M. Carotenoid oxidation products are stress signals that mediate gene responses to singlet oxygen in plants. Proc Natl Acad Sci U S A. 2012;109:5535-40 pubmed publisher
    1)O(2) (singlet oxygen) is a reactive O(2) species produced from triplet excited chlorophylls in the chloroplasts, especially when plants are exposed to excess light energy...
  37. Dabrowski J, Arnaut L, Pereira M, Urbanska K, Simoes S, Stochel G, et al. Combined effects of singlet oxygen and hydroxyl radical in photodynamic therapy with photostable bacteriochlorins: evidence from intracellular fluorescence and increased photodynamic efficacy in vitro. Free Radic Biol Med. 2012;52:1188-200 pubmed publisher
    ..The roles of type I and type II photochemical processes are assessed by singlet oxygen luminescence and intracellular hydroxyl radical detection...
  38. Gutierrez J, González Pérez S, Garcia Garcia F, Lorenzo O, Arellano J. Does singlet oxygen activate cell death in Arabidopsis cell suspension cultures?: analysis of the early transcriptional defense responses to high light stress. Plant Signal Behav. 2011;6:1937-42 pubmed
    ..The results showed that ACSC respond to HL in a manner that resembles the singlet oxygen ((1)O(2))-mediated defense responses described for the conditional fluorescent (flu) mutant of Arabidopsis ..
  39. Nam T, ZIEGELHOFFER E, Lemke R, Donohue T. Proteins needed to activate a transcriptional response to the reactive oxygen species singlet oxygen. MBio. 2013;4:e00541-12 pubmed publisher
    b>Singlet oxygen ((1)O(2)) is a reactive oxygen species generated by energy transfer from one or more excited donors to molecular oxygen...
  40. Chiarelli Neto O, Pavani C, Ferreira A, Uchoa A, Severino D, Baptista M. Generation and suppression of singlet oxygen in hair by photosensitization of melanin. Free Radic Biol Med. 2011;51:1195-202 pubmed publisher
    ..and black) under illumination with visible light, giving special emphasis to the photoinduced generation of singlet oxygen ((1)O(2)). Irradiation of hair shafts (?(ex)>400 nm) changed their properties by degrading the melanin...
  41. Brzezowski P, Wilson K, Gray G. The PSBP2 protein of Chlamydomonas reinhardtii is required for singlet oxygen-dependent signaling. Planta. 2012;236:1289-303 pubmed
    ..cytosolic Glutathione Peroxidase 5 gene (GPX5) is known to be transcriptionally up-regulated in response to singlet oxygen ((1)O(2))...
  42. Dufour Y, Imam S, Koo B, Green H, Donohue T. Convergence of the transcriptional responses to heat shock and singlet oxygen stresses. PLoS Genet. 2012;8:e1002929 pubmed publisher
    ..response, while those specific to RpoH(II) are associated with the response to the reactive oxygen species, singlet oxygen. We propose that a gene duplication event followed by changes in promoter recognition by RpoH(I) and RpoH(II) ..
  43. Geer M, Walla M, Solntsev K, Strassert C, Shimizu L. Self-assembled benzophenone bis-urea macrocycles facilitate selective oxidations by singlet oxygen. J Org Chem. 2013;78:5568-78 pubmed publisher
    ..As expected, UV irradiation of the host suspended in oxygenated solvents efficiently generates singlet oxygen similar to the parent benzophenone...
  44. Osawa A, Iki K, Sandmann G, Shindo K. Isolation and identification of 4, 4'-diapolycopene-4,4'-dioic acid produced by Bacillus firmus GB1 and its singlet oxygen quenching activity. J Oleo Sci. 2013;62:955-60 pubmed
    ..In addition, we clarified the singlet oxygen (¹O?) quenching activities of 4,4'-diapolycopene-4,4'-dioic acid and its methyl esters (mono and dimethyl ..
  45. Zebger I, Snyder J, Andersen L, Poulsen L, Gao Z, Lambert J, et al. Direct optical detection of singlet oxygen from a single cell. Photochem Photobiol. 2004;79:319-22 pubmed
    b>Singlet oxygen has been detected in single nerve cells by its weak 1270 nm phosphorescence (a1deltag --> X3sigmag-) upon irradiation of a photosensitizer incorporated in the cell...
  46. Baier J, Fuss T, Pöllmann C, Wiesmann C, Pindl K, Engl R, et al. Theoretical and experimental analysis of the luminescence signal of singlet oxygen for different photosensitizers. J Photochem Photobiol B. 2007;87:163-73 pubmed
    After the generation by different photosensitizers, the direct detection of singlet oxygen is performed by measuring its luminescence at 1270 nm...
  47. Chen J, Stefflova K, Niedre M, Wilson B, Chance B, Glickson J, et al. Protease-triggered photosensitizing beacon based on singlet oxygen quenching and activation. J Am Chem Soc. 2004;126:11450-1 pubmed
    ..Upon caspase-3-induced cleavage, the 1O2 production increased markedly, as measured directly by 1O2 near-infrared luminescence and lifetime measurements...
  48. Fischer B, Krieger Liszkay A, Eggen R. Photosensitizers neutral red (type I) and rose bengal (type II) cause light-dependent toxicity in Chlamydomonas reinhardtii and induce the Gpxh gene via increased singlet oxygen formation. Environ Sci Technol. 2004;38:6307-13 pubmed
    ..The toxicity of RB was reduced by the singlet oxygen (1O2) quenchers 1,4-diazabicyclo[2.2...
  49. Ma J, Chen J, Idowu M, Nyokong T. Generation of singlet oxygen via the composites of water-soluble thiol-capped CdTe quantum dots-sulfonated aluminum phthalocyanines. J Phys Chem B. 2008;112:4465-9 pubmed publisher
    b>Singlet oxygen (1O2), one of the reactive oxygen species, plays an important role in many biomedical applications...
  50. Rule Wigginton K, Menin L, Montoya J, Kohn T. Oxidation of virus proteins during UV(254) and singlet oxygen mediated inactivation. Environ Sci Technol. 2010;44:5437-43 pubmed publisher
    ..These results suggest that viral protein oxidation by UV(254) and (1)O(2) may play a role in virus inactivation and that viral inactivation may be tracked with mass spectrometric measurements...
  51. Ragàs X, Agut M, Nonell S. Singlet oxygen in Escherichia coli: New insights for antimicrobial photodynamic therapy. Free Radic Biol Med. 2010;49:770-6 pubmed publisher
    ..of the photoactive drug in the bacteria and about the details of production of the main cytotoxic species, singlet oxygen. This article describes a combination of spectroscopic and time-resolved photophysical techniques that provide ..
  52. Samol I, Buhr F, Springer A, Pollmann S, Lahroussi A, Rossig C, et al. Implication of the oep16-1 mutation in a flu-independent, singlet oxygen-regulated cell death pathway in Arabidopsis thaliana. Plant Cell Physiol. 2011;52:84-95 pubmed publisher
    b>Singlet oxygen is a prominent form of reactive oxygen species in higher plants. It is easily formed from molecular oxygen by triplet-triplet interchange with excited porphyrin species...
  53. Shen X, He F, Wu J, Xu G, Yao S, Xu Q. Enhanced two-photon singlet oxygen generation by photosensitizer-doped conjugated polymer nanoparticles. Langmuir. 2011;27:1739-44 pubmed publisher
    ..Enhanced two-photon excitation singlet oxygen generation efficiency in the TPP-doped PFEMO nanoparticles has been demonstrated...