lanthanoid series elements

Summary

Summary: Elements of the lanthanoid series including atomic number 57 (LANTHANUM) through atomic number 71 (LUTETIUM).

Top Publications

  1. Huhtinen P, Kivelä M, Kuronen O, Hagren V, Takalo H, Tenhu H, et al. Synthesis, characterization, and application of Eu(III), Tb(III), Sm(III), and Dy(III) lanthanide chelate nanoparticle labels. Anal Chem. 2005;77:2643-8 pubmed
    ..The spectral and functional properties of the lanthanide-embedded polystyrene nanoparticles developed here suggest that the technology is applicable for high-sensitivity multicolor assays...
  2. Smith D, Rossi C, Kijek T, Henchal E, Ludwig G. Comparison of dissociation-enhanced lanthanide fluorescent immunoassays to enzyme-linked immunosorbent assays for detection of staphylococcal enterotoxin B, Yersinia pestis-specific F1 antigen, and Venezuelan equine encephalitis virus. Clin Diagn Lab Immunol. 2001;8:1070-5 pubmed
  3. Wöhnert J, Franz K, Nitz M, Imperiali B, Schwalbe H. Protein alignment by a coexpressed lanthanide-binding tag for the measurement of residual dipolar couplings. J Am Chem Soc. 2003;125:13338-9 pubmed
    ..6 to 6.1 Hz for Dy3+, while an opposite alignment tensor is observed for Tm3+ (4.5 to -2.9 Hz) at 800 MHz. Experimental RDCs are in excellent agreement with those predicted on the basis of the X-ray structure of the protein...
  4. Pintacuda G, John M, Su X, Otting G. NMR structure determination of protein-ligand complexes by lanthanide labeling. Acc Chem Res. 2007;40:206-12 pubmed
    ..Strategies for site-specific incorporation of lanthanide ions into proteins are summarized...
  5. Liu Q, Sun Y, Yang T, Feng W, Li C, Li F. Sub-10 nm hexagonal lanthanide-doped NaLuF4 upconversion nanocrystals for sensitive bioimaging in vivo. J Am Chem Soc. 2011;133:17122-5 pubmed publisher
  6. Anan Y, Awaya Y, Ogihara Y, Yoshida M, Yawata A, Ogra Y. Comparison in accumulation of lanthanide elements among three Brassicaceae plant sprouts. Bull Environ Contam Toxicol. 2012;89:133-7 pubmed publisher
    ..Faster growth compensated for less efficiency in lanthanide accumulation (28 pmol La in the radish vs. 12 pmol La in the mustard) indicating that the radish is the most preferable sprout for the phytoremediation of lanthanides...
  7. Saio T, Ogura K, Shimizu K, Yokochi M, Burke T, Inagaki F. An NMR strategy for fragment-based ligand screening utilizing a paramagnetic lanthanide probe. J Biomol NMR. 2011;51:395-408 pubmed publisher
    ..The usefulness of this strategy was demonstrated in the case of the growth factor receptor-bound protein 2 (Grb2) Src homology 2 (SH2) domain and its low- and high-affinity ligands...
  8. Graham B, Loh C, Swarbrick J, Ung P, Shin J, Yagi H, et al. DOTA-amide lanthanide tag for reliable generation of pseudocontact shifts in protein NMR spectra. Bioconjug Chem. 2011;22:2118-25 pubmed publisher
    ..The performance of the tag is demonstrated with the N-terminal domain of the E. coli arginine repressor and the A28C mutant of human ubiquitin...
  9. Protano G, Riccobono F. High contents of rare earth elements (REEs) in stream waters of a Cu-Pb-Zn mining area. Environ Pollut. 2002;117:499-514 pubmed
    ..The origin of the "roof-shaped" REE distribution pattern as well as the peculiar geochemical behavior of some lanthanide elements in the aqueous system are discussed...

More Information

Publications62

  1. Haussinger D, Huang J, Grzesiek S. DOTA-M8: An extremely rigid, high-affinity lanthanide chelating tag for PCS NMR spectroscopy. J Am Chem Soc. 2009;131:14761-7 pubmed publisher
  2. Gregoliński J, Starynowicz P, Hua K, Lunkley J, Muller G, Lisowski J. Helical lanthanide(III) complexes with chiral nonaaza macrocycle. J Am Chem Soc. 2008;130:17761-73 pubmed publisher
  3. Hanaoka K, Kikuchi K, Kobayashi S, Nagano T. Time-resolved long-lived luminescence imaging method employing luminescent lanthanide probes with a new microscopy system. J Am Chem Soc. 2007;129:13502-9 pubmed
    ..This new imaging technique should facilitate investigations of biological functions with fluorescence microscopy, complementing other fluorescence imaging methodologies...
  4. Bertini I, Gupta Y, Luchinat C, Parigi G, Peana M, Sgheri L, et al. Paramagnetism-based NMR restraints provide maximum allowed probabilities for the different conformations of partially independent protein domains. J Am Chem Soc. 2007;129:12786-94 pubmed
    ..Such variety is somewhat reduced in the calmodulin-alpha-synuclein adduct, which however still retains high flexibility. The flexibility of the calmodulin-alpha-synuclein adduct is an unexpected result of this research...
  5. Bünzli J, Piguet C. Taking advantage of luminescent lanthanide ions. Chem Soc Rev. 2005;34:1048-77 pubmed
    ..Recent advances in NIR-emitting materials, including liquid crystals, and in the control of luminescent properties in polymetallic assemblies are also presented. (210 references.)...
  6. Nitz M, Sherawat M, Franz K, Peisach E, Allen K, Imperiali B. Structural origin of the high affinity of a chemically evolved lanthanide-binding peptide. Angew Chem Int Ed Engl. 2004;43:3682-5 pubmed
  7. Bertini I, Gelis I, Katsaros N, Luchinat C, Provenzani A. Tuning the affinity for lanthanides of calcium binding proteins. Biochemistry. 2003;42:8011-21 pubmed
    ..Finally, by using CaM samples containing only three of the four calcium ions, it was possible to prepare well-defined Ca(3)Ln-CaM derivatives (Ln = Tb, Dy, Tm, and Yb), with interesting properties as NMR probes...
  8. Saio T, Ogura K, Yokochi M, Kobashigawa Y, Inagaki F. Two-point anchoring of a lanthanide-binding peptide to a target protein enhances the paramagnetic anisotropic effect. J Biomol NMR. 2009;44:157-66 pubmed publisher
    ..Though there is slight residual mobility of the lanthanide-binding tag, the present tag provides a higher anisotropic paramagnetic effect...
  9. Song B, Vandevyver C, Chauvin A, Bünzli J. Time-resolved luminescence microscopy of bimetallic lanthanide helicates in living cells. Org Biomol Chem. 2008;6:4125-33 pubmed publisher
    ..43 ms], compared to >10 microM when using conventional luminescence microscopy. Furthermore, multiplex labeling could be achieved with the Tb(III) [Q = 0.11, tau = 0.65 ms], and Sm(III) [Q = 0.0038, tau = 0.030 ms] analogues...
  10. Hemmilä I, Laitala V. Progress in lanthanides as luminescent probes. J Fluoresc. 2005;15:529-42 pubmed
    ..This review gives a short overview of recent development of lanthanide chelate-labels and discusses in more details of energy levels and their exploitation in new assay formats...
  11. Pintacuda G, Park A, Keniry M, Dixon N, Otting G. Lanthanide labeling offers fast NMR approach to 3D structure determinations of protein-protein complexes. J Am Chem Soc. 2006;128:3696-702 pubmed
    ..Degeneracies in the mutual orientation of the protein structures were resolved by the use of two different lanthanide ions, Dy3+ and Er3+...
  12. Tsukube H, Shinoda S. Lanthanide complexes in molecular recognition and chirality sensing of biological substrates. Chem Rev. 2002;102:2389-403 pubmed
  13. Eliseeva S, Bünzli J. Lanthanide luminescence for functional materials and bio-sciences. Chem Soc Rev. 2010;39:189-227 pubmed publisher
  14. Wang F, Han Y, Lim C, Lu Y, Wang J, Xu J, et al. Simultaneous phase and size control of upconversion nanocrystals through lanthanide doping. Nature. 2010;463:1061-5 pubmed publisher
  15. John M, Pintacuda G, Park A, Dixon N, Otting G. Structure determination of protein-ligand complexes by transferred paramagnetic shifts. J Am Chem Soc. 2006;128:12910-6 pubmed
    ..The binding mode of thymidine was found to be very similar to that of thymidine monophosphate present in the crystal structure...
  16. Ikegami T, Verdier L, Sakhaii P, Grimme S, Pescatore B, Saxena K, et al. Novel techniques for weak alignment of proteins in solution using chemical tags coordinating lanthanide ions. J Biomol NMR. 2004;29:339-49 pubmed
    ..We observed residual (15)N,(1)H-dipolar couplings of up to 8 Hz at 800 MHz induced by a single alignment tensor from this tag...
  17. Xu X, Keizers P, Reinle W, Hannemann F, Bernhardt R, Ubbink M. Intermolecular dynamics studied by paramagnetic tagging. J Biomol NMR. 2009;43:247-54 pubmed publisher
    ..The applied method provides a simple and straightforward way to observe dynamics in protein complexes or domain-domain mobility without the need for external alignment media...
  18. Su X, McAndrew K, Huber T, Otting G. Lanthanide-binding peptides for NMR measurements of residual dipolar couplings and paramagnetic effects from multiple angles. J Am Chem Soc. 2008;130:1681-7 pubmed publisher
  19. Wu S, Han G, Milliron D, Aloni S, Altoe V, Talapin D, et al. Non-blinking and photostable upconverted luminescence from single lanthanide-doped nanocrystals. Proc Natl Acad Sci U S A. 2009;106:10917-21 pubmed publisher
    ..These UCNPs are endocytosed by cells and show strong upconverted luminescence, with no measurable anti-Stokes background autofluorescence, suggesting that UCNPs are ideally suited for single-molecule imaging experiments...
  20. Selvin P. Principles and biophysical applications of lanthanide-based probes. Annu Rev Biophys Biomol Struct. 2002;31:275-302 pubmed
  21. De Silva C, Vagner J, Lynch R, Gillies R, Hruby V. Optimization of time-resolved fluorescence assay for detection of europium-tetraazacyclododecyltetraacetic acid-labeled ligand-receptor interactions. Anal Biochem. 2010;398:15-23 pubmed publisher
    ..The modified assay provides superior results and is appropriate for high-throughput screening of ligand libraries...
  22. Su X, Man B, Beeren S, Liang H, Simonsen S, Schmitz C, et al. A dipicolinic acid tag for rigid lanthanide tagging of proteins and paramagnetic NMR spectroscopy. J Am Chem Soc. 2008;130:10486-7 pubmed publisher
    ..The close proximity of the lanthanide ion promotes accurate determinations of magnetic susceptibility anisotropy tensors. In addition, the small size of the tag makes it highly suitable for studies of intermolecular interactions...
  23. Prud ncio M, Rohovec J, Peters J, Tocheva E, Boulanger M, Murphy M, et al. A caged lanthanide complex as a paramagnetic shift agent for protein NMR. Chemistry. 2004;10:3252-60 pubmed publisher
    ..The molecule exists in several isomeric forms with different paramagnetic tensors; this provides a fast way to obtain long-range distance restraints...
  24. Vlasie M, Comuzzi C, van den Nieuwendijk A, Prudêncio M, Overhand M, Ubbink M. Long-range-distance NMR effects in a protein labeled with a lanthanide-DOTA chelate. Chemistry. 2007;13:1715-23 pubmed
    ..This study demonstrates that bidentate attachment of a paramagnetic probe enables determination of long-range distances...
  25. Kuningas K, Rantanen T, Karhunen U, Lövgren T, Soukka T. Simultaneous use of time-resolved fluorescence and anti-stokes photoluminescence in a bioaffinity assay. Anal Chem. 2005;77:2826-34 pubmed
    ..In this study we show that up-converting anti-Stokes photoluminescent phosphors could be employed in bioaffinity assays as very potential labels with significant advantages either alone or together with long-lifetime lanthanide chelates...
  26. Barthelmes K, Reynolds A, Peisach E, Jonker H, Denunzio N, Allen K, et al. Engineering encodable lanthanide-binding tags into loop regions of proteins. J Am Chem Soc. 2011;133:808-19 pubmed publisher
    ..The current data provide support that encodable LBTs serve as versatile biophysical tags when inserted into loop regions of proteins of known structure or predicted via homology modeling...
  27. Terenghi M, Elviri L, Careri M, Mangia A, Lobinski R. Multiplexed determination of protein biomarkers using metal-tagged antibodies and size exclusion chromatography--inductively coupled plasma mass spectrometry. Anal Chem. 2009;81:9440-8 pubmed publisher
    ..3 times lower than an ELISA test. The method was validated for the analysis of the proteins in human serum and proved to be able to discriminate ovary and uterus tumor tissue samples from those of healthy subjects...
  28. Boyer J, Vetrone F, Cuccia L, Capobianco J. Synthesis of colloidal upconverting NaYF4 nanocrystals doped with Er3+, Yb3+ and Tm3+, Yb3+ via thermal decomposition of lanthanide trifluoroacetate precursors. J Am Chem Soc. 2006;128:7444-5 pubmed
  29. Su X, Huber T, Dixon N, Otting G. Site-specific labelling of proteins with a rigid lanthanide-binding tag. Chembiochem. 2006;7:1599-604 pubmed
  30. Chatterjee D, Rufaihah A, Zhang Y. Upconversion fluorescence imaging of cells and small animals using lanthanide doped nanocrystals. Biomaterials. 2008;29:937-43 pubmed
    ..To the best of our knowledge, this represents the first demonstration of use of upconversion fluorophores for cellular and tissue imaging...
  31. Barbieri R, Bertini I, Cavallaro G, Lee Y, Luchinat C, Rosato A. Paramagnetically induced residual dipolar couplings for solution structure determination of lanthanide binding proteins. J Am Chem Soc. 2002;124:5581-7 pubmed
    ..The effect of mobility is also assessed. In principle, information on the mobility can be obtained with a number of lanthanide ions >5, or by combining a smaller number of lanthanide ions with a few orienting devices...
  32. Keizers P, Saragliadis A, Hiruma Y, Overhand M, Ubbink M. Design, synthesis, and evaluation of a lanthanide chelating protein probe: CLaNP-5 yields predictable paramagnetic effects independent of environment. J Am Chem Soc. 2008;130:14802-12 pubmed publisher
    ..These findings designate CLaNP-5 as a protein probe to deliver unambiguous high quality structural restraints in studies on protein-protein and protein-ligand interactions...
  33. Zuchner T, Schumer F, Berger Hoffmann R, Muller K, Lukas M, Zeckert K, et al. Highly sensitive protein detection based on lanthanide chelates with antenna ligands providing a linear range of five orders of magnitude. Anal Chem. 2009;81:9449-53 pubmed publisher
    ..In addition, the new compound offers multiplexing capabilities...
  34. Bünzli J. Benefiting from the unique properties of lanthanide ions. Acc Chem Res. 2006;39:53-61 pubmed
  35. Saio T, Yokochi M, Kumeta H, Inagaki F. PCS-based structure determination of protein-protein complexes. J Biomol NMR. 2010;46:271-80 pubmed publisher
  36. Frullano L, Meade T. Multimodal MRI contrast agents. J Biol Inorg Chem. 2007;12:939-49 pubmed
  37. Bertini I, Kursula P, Luchinat C, Parigi G, Vahokoski J, Wilmanns M, et al. Accurate solution structures of proteins from X-ray data and a minimal set of NMR data: calmodulin-peptide complexes as examples. J Am Chem Soc. 2009;131:5134-44 pubmed publisher
  38. Ehlert O, Thomann R, Darbandi M, Nann T. A four-color colloidal multiplexing nanoparticle system. ACS Nano. 2008;2:120-4 pubmed publisher
    ..The particles were phase transferred into polar solvents by means of silica encapsulation and were characterized by transmission electron microscopy, X-ray diffraction, and photoluminescence spectroscopy...
  39. Niu W, Wu S, Zhang S, Li J, Li L. Multicolor output and shape controlled synthesis of lanthanide-ion doped fluorides upconversion nanoparticles. Dalton Trans. 2011;40:3305-14 pubmed publisher
  40. Wang F, Liu X. Upconversion multicolor fine-tuning: visible to near-infrared emission from lanthanide-doped NaYF4 nanoparticles. J Am Chem Soc. 2008;130:5642-3 pubmed publisher
    ..The approach allows access to a wide range of luminescence emission from visible to near-infrared by single-wavelength excitation...
  41. Swarbrick J, Ung P, Su X, Maleckis A, Chhabra S, Huber T, et al. Engineering of a bis-chelator motif into a protein ?-helix for rigid lanthanide binding and paramagnetic NMR spectroscopy. Chem Commun (Camb). 2011;47:7368-70 pubmed publisher
  42. Regueiro Figueroa M, Bensenane B, Ruscsák E, Esteban Gómez D, Charbonnière L, Tircsó G, et al. Lanthanide dota-like complexes containing a picolinate pendant: structural entry for the design of Ln(III)-based luminescent probes. Inorg Chem. 2011;50:4125-41 pubmed publisher
    ..However, these rates are 1-2 orders of magnitude lower than those of do3a analogues, which shows that the complexes reported herein are remarkably inert with respect to metal ion dissociation...
  43. Li Z, Zhang Y, Shuter B, Muhammad Idris N. Hybrid lanthanide nanoparticles with paramagnetic shell coated on upconversion fluorescent nanocrystals. Langmuir. 2009;25:12015-8 pubmed publisher
  44. Su X, Otting G. Paramagnetic labelling of proteins and oligonucleotides for NMR. J Biomol NMR. 2010;46:101-12 pubmed publisher
    ..The paramagnetic tags include nitroxide radicals and metal chelators. Particular emphasis is placed on tags suitable for site-specific and rigid attachment of lanthanide ions to macromolecules...
  45. Martin L, Hähnke M, Nitz M, Wöhnert J, Silvaggi N, Allen K, et al. Double-lanthanide-binding tags: design, photophysical properties, and NMR applications. J Am Chem Soc. 2007;129:7106-13 pubmed
    ..Together, these results indicate that dLBTs will be valuable chemical tools for biophysical applications leading to new approaches for studying the structure, function, and dynamics of proteins...
  46. Haberz P, Rodriguez Castaneda F, Junker J, Becker S, Leonov A, Griesinger C. Two new chiral EDTA-based metal chelates for weak alignment of proteins in solution. Org Lett. 2006;8:1275-8 pubmed
    ..Alignment tensors for the new tags are linearly independent compared to those of previously published tags...
  47. Leonov A, Voigt B, Rodriguez Castaneda F, Sakhaii P, Griesinger C. Convenient synthesis of multifunctional EDTA-based chiral metal chelates substituted with an S-mesylcysteine. Chemistry. 2005;11:3342-8 pubmed
  48. Ali M, Liu G, Shah T, Flask C, Pagel M. Using two chemical exchange saturation transfer magnetic resonance imaging contrast agents for molecular imaging studies. Acc Chem Res. 2009;42:915-24 pubmed publisher
    ..This example demonstrates current limitations of the method that require additional research, but it also shows that two CEST MRI contrast agents can be detected and quantitatively assessed during in vivo molecular imaging studies...
  49. Moore E, Samuel A, Raymond K. From antenna to assay: lessons learned in lanthanide luminescence. Acc Chem Res. 2009;42:542-52 pubmed publisher
    ..Lastly, we describe a Tb(III)-IAM compound--now carried through to commercial availability--that offers improved performance in the common HTRF platform and has the potential to vastly improve sensitivity...
  50. Jin D, Piper J. Time-gated luminescence microscopy allowing direct visual inspection of lanthanide-stained microorganisms in background-free condition. Anal Chem. 2011;83:2294-300 pubmed publisher
    ..The availability of low-cost, robust time-gated microscopes will aid development of long-lifetime luminescence bioprobes and accelerate their application in routine laboratory diagnostics...
  51. Otting G. Prospects for lanthanides in structural biology by NMR. J Biomol NMR. 2008;42:1-9 pubmed publisher
    ..Cell-free protein synthesis is positioned to play an important role in this strategy, as an inexpensive source of selectively labelled protein samples and for easy site-specific incorporation of unnatural lanthanide-binding amino acids...
  52. John M, Schmitz C, Park A, Dixon N, Huber T, Otting G. Sequence-specific and stereospecific assignment of methyl groups using paramagnetic lanthanides. J Am Chem Soc. 2007;129:13749-57 pubmed
    ..The approaches are demonstrated with the complex between the N-terminal domain of the subunit epsilon and the subunit theta of the Escherichia coli DNA polymerase III...
  53. Keizers P, Desreux J, Overhand M, Ubbink M. Increased paramagnetic effect of a lanthanide protein probe by two-point attachment. J Am Chem Soc. 2007;129:9292-3 pubmed