radon

Summary

Summary: A naturally radioactive element with atomic symbol Rn, and atomic number 86. It is a member of the noble gas family found in soil, and is released during the decay of RADIUM.

Top Publications

  1. Kataoka T, Teraoka J, Sakoda A, Nishiyama Y, Yamato K, Monden M, et al. Protective effects of radon inhalation on carrageenan-induced inflammatory paw edema in mice. Inflammation. 2012;35:713-22 pubmed publisher
    We assessed whether radon inhalation inhibited carrageenan-induced inflammation in mice. Carrageenan (1% v/v) was injected subcutaneously into paws of mice that had or had not inhaled approximately 2,000 Bq/m(3) of radon for 24 h...
  2. Zhang Z, Sun J, Dong J, Tian H, Xue L, Qin L, et al. Residential radon and lung cancer risk: an updated meta- analysis of case-control studies. Asian Pac J Cancer Prev. 2012;13:2459-65 pubmed
    Numbers of epidemiological studies assessing residential radon exposure and risk of lung cancer have yielded inconsistent results.
  3. Chahine T, Schultz B, Zartarian V, Xue J, Subramanian S, Levy J. Modeling joint exposures and health outcomes for cumulative risk assessment: the case of radon and smoking. Int J Environ Res Public Health. 2011;8:3688-711 pubmed publisher
    ..Residential radon provides an interesting case example, given its large attributable risk, effect modification due to smoking, and ..
  4. Bräuner E, Andersen Z, Andersen C, Pedersen C, Gravesen P, Ulbak K, et al. Residential radon and brain tumour incidence in a Danish cohort. PLoS ONE. 2013;8:e74435 pubmed publisher
    Increased brain tumour incidence over recent decades may reflect improved diagnostic methods and clinical practice, but remain unexplained. Although estimated doses are low a relationship between radon and brain tumours may exist.
  5. Gruber V, Bossew P, De Cort M, Tollefsen T. The European map of the geogenic radon potential. J Radiol Prot. 2013;33:51-60 pubmed publisher
    ..institutions and radioprotection authorities all over Europe, is currently developing a map of the geogenic radon potential. In an accompanying report the state of knowledge, mapping approaches and problems are discussed...
  6. Leuraud K, Schnelzer M, Tomasek L, Hunter N, Timarche M, Grosche B, et al. Radon, smoking and lung cancer risk: results of a joint analysis of three European case-control studies among uranium miners. Radiat Res. 2011;176:375-87 pubmed
    ..case-control studies nested in three European uranium miner cohorts was performed to study the joint effects of radon exposure and smoking on lung cancer death risk...
  7. Schubert M, Paschke A, Lieberman E, Burnett W. Air-water partitioning of 222Rn and its dependence on water temperature and salinity. Environ Sci Technol. 2012;46:3905-11 pubmed publisher
    b>Radon is useful as a tracer of certain geophysical processes in marine and aquatic environments. Recent applications include detection of groundwater discharges into surface waters and assessment of air/sea gas piston velocities...
  8. Farkas A, Hofmann W, Balashazy I, Szoke I, Madas B, Moustafa M. Effect of site-specific bronchial radon progeny deposition on the spatial and temporal distributions of cellular responses. Radiat Environ Biophys. 2011;50:281-97 pubmed publisher
    Inhaled short-lived radon progenies may deposit in bronchial airways and interact with the epithelium by the emission of alpha particles...
  9. Barros Dios J, Ruano Ravina A, Pérez Ríos M, Castro Bernárdez M, Abal Arca J, Tojo Castro M. Residential radon exposure, histologic types, and lung cancer risk. A case-control study in Galicia, Spain. Cancer Epidemiol Biomarkers Prev. 2012;21:951-8 pubmed publisher
    Lung cancer is an important public health problem, and tobacco is the main risk factor followed by residential radon exposure. Recommended exposure levels have been progressively lowered...

More Information

Publications62

  1. Milner J, Shrubsole C, Das P, Jones B, Ridley I, Chalabi Z, et al. Home energy efficiency and radon related risk of lung cancer: modelling study. BMJ. 2014;348:f7493 pubmed publisher
    To investigate the effect of reducing home ventilation as part of household energy efficiency measures on deaths from radon related lung cancer.
  2. Kataoka T, Sakoda A, Ishimori Y, Toyota T, Nishiyama Y, Tanaka H, et al. Study of the response of superoxide dismutase in mouse organs to radon using a new large-scale facility for exposing small animals to radon. J Radiat Res. 2011;52:775-81 pubmed
    ..changes of superoxide dismutase (SOD) activity using a new large-scale facility for exposing small animals to radon. Mice were exposed to radon at a concentration of 250, 500, 1000, 2000, or 4000 Bq/m(3) for 0...
  3. Ishimori Y, Mitsunobu F, Yamaoka K, Tanaka H, Kataoka T, Sakoda A. Performance of the first Japanese large-scale facility for radon inhalation experiments with small animals. Radiat Prot Dosimetry. 2011;146:31-3 pubmed publisher
    A radon test facility for small animals was developed in order to increase the statistical validity of differences of the biological response in various radon environments...
  4. Shaw S, Eckhardt D. An assessment of radon in groundwater in New York state. Health Phys. 2012;103:311-6 pubmed publisher
    ..throughout New York State (excluding Long Island) from 2003 through 2008 was used to assess the distribution of radon gas in drinking water...
  5. Chen J, Moir D. A study on the thoron sensitivity of radon detectors available to Canadians. J Radiol Prot. 2012;32:419-25 pubmed publisher
    b>Radon and its decay products have been identified as the second leading cause of lung cancer after tobacco smoking. Thoron is an isotope of radon. With increased awareness of radon, questions related to thoron are arising from the public...
  6. Kataoka T, Nishiyama Y, Yamato K, Teraoka J, Morii Y, Sakoda A, et al. Comparative study on the inhibitory effects of antioxidant vitamins and radon on carbon tetrachloride-induced hepatopathy. J Radiat Res. 2012;53:830-9 pubmed publisher
    We have previously reported that radon inhalation activates anti-oxidative functions and inhibits carbon tetrachloride (CCl(4))-induced hepatopathy...
  7. Peterson E, Aker A, Kim J, Li Y, Brand K, Copes R. Lung cancer risk from radon in Ontario, Canada: how many lung cancers can we prevent?. Cancer Causes Control. 2013;24:2013-20 pubmed publisher
    To calculate the burden of lung cancer illness due to radon for all thirty-six health units in Ontario and determine the number of radon-attributable lung cancer deaths that could be prevented.
  8. Kendall G, Little M, Wakeford R, Bunch K, Miles J, Vincent T, et al. A record-based case-control study of natural background radiation and the incidence of childhood leukaemia and other cancers in Great Britain during 1980-2006. Leukemia. 2013;27:3-9 pubmed publisher
    ..mean for gamma rays, and a predictive map based on domestic measurements grouped by geological boundaries for radon. There was 12% excess relative risk (ERR) (95% CI 3, 22; two-sided P=0...
  9. Bräuner E, Andersen C, Sørensen M, Andersen Z, Gravesen P, Ulbak K, et al. Residential radon and lung cancer incidence in a Danish cohort. Environ Res. 2012;118:130-6 pubmed publisher
    High-level occupational radon exposure is an established risk factor for lung cancer...
  10. Tomasek L. Lung cancer in a Czech cohort exposed to radon in dwellings--50 years of follow-up. Neoplasma. 2012;59:559-65 pubmed publisher
    The presented study reports lung cancer mortality in a cohort of 11 842 subjects exposed to high levels of radon covering the period 1961-2010...
  11. Tomasek L. Lung cancer mortality among Czech uranium miners-60 years since exposure. J Radiol Prot. 2012;32:301-14 pubmed publisher
    ..Lung cancer in relation to cumulative exposure to radon decay products is linear with substantial modifications by time since exposure, age at exposure and exposure rate ..
  12. Sethi T, El Ghamry M, Kloecker G. Radon and lung cancer. Clin Adv Hematol Oncol. 2012;10:157-64 pubmed
    Lung cancer is the leading cause of cancer-related deaths worldwide. Radon exposure is the second leading cause of lung cancer, following tobacco smoke...
  13. Bavarnegin E, Fathabadi N, Vahabi Moghaddam M, Vasheghani Farahani M, Moradi M, Babakhni A. Radon exhalation rate and natural radionuclide content in building materials of high background areas of Ramsar, Iran. J Environ Radioact. 2013;117:36-40 pubmed publisher
    b>Radon exhalation rates from building materials used in high background radiation areas (HBRA) of Ramsar were measured using an active radon gas analyzer with an emanation container...
  14. Torres Durán M, Barros Dios J, Fernández Villar A, Ruano Ravina A. Residential radon and lung cancer in never smokers. A systematic review. Cancer Lett. 2014;345:21-6 pubmed publisher
    b>Radon exposure is considered the second cause of lung cancer and the first in never smokers...
  15. Nissen M, Leach J, Nissen J, Swenson K, Kehn H. Radon testing and mitigation: an intervention in a primary care setting. J Cancer Educ. 2012;27:566-72 pubmed publisher
    b>Radon is the second leading cause of lung cancer and it is recommended that all homes be tested for radon. Written surveys completed by 692 patients at two primary care clinics in the Minneapolis, MN, area revealed that only 24...
  16. Tong J, Qin L, Cao Y, Li J, Zhang J, Nie J, et al. Environmental radon exposure and childhood leukemia. J Toxicol Environ Health B Crit Rev. 2012;15:332-47 pubmed publisher
    Despite the fact that animal and human epidemiological studies confirmed a link between radon exposure in homes and increased risk of lung cancer in general population, other types of cancers induced by radon, such as leukemia, have not ..
  17. Kumar S, Singh S, Bajwa B, Sabharwal A. In situ measurements of radon levels in water and soil and exhalation rate in areas of Malwa belt of Punjab (India). Isotopes Environ Health Stud. 2011;47:446-55 pubmed publisher
    b>Radon concentration levels in water and soil gas from 36 locations pertaining to some areas of Malwa region of Punjab have been measured on an in situ basis using a continuous active radon detector (AlphaGuard, Model - PQ 2000 PRO, ..
  18. Veloso B, Nogueira J, Cardoso M. Lung cancer and indoor radon exposure in the north of Portugal--an ecological study. Cancer Epidemiol. 2012;36:e26-32 pubmed publisher
    Indoor radon exposure is a well documented environmental factor as a leading cause of lung cancer.
  19. Wheeler B, Allen J, Depledge M, Curnow A. Radon and skin cancer in southwest England: an ecologic study. Epidemiology. 2012;23:44-52 pubmed publisher
    b>Radon, a naturally occurring radioactive gas, is a carcinogen that causes a small proportion of lung cancers among exposed populations...
  20. Madas B, Balashazy I. Mutation induction by inhaled radon progeny modeled at the tissue level. Radiat Environ Biophys. 2011;50:553-70 pubmed publisher
    ..of radiation manifest at the tissue level by modeling mutation induction due to chronic exposure to inhaled radon progeny...
  21. Vacquier B, Rage E, Leuraud K, Caër Lorho S, Houot J, Acker A, et al. The influence of multiple types of occupational exposure to radon, gamma rays and long-lived radionuclides on mortality risk in the French "post-55" sub-cohort of uranium miners: 1956-1999. Radiat Res. 2011;176:796-806 pubmed
    The adverse health effects of radon on uranium miners, especially on their lungs, are well documented, but few studies have considered the effects of other radiation exposures...
  22. Ashok G, Nagaiah N, Shiva Prasad N. Indoor radon concentration and its possible dependence on ventilation rate and flooring type. Radiat Prot Dosimetry. 2012;148:92-100 pubmed publisher
    The results of radon concentration measurements carried out in dwellings with natural ventilation for 1 y in Bangalore are reported...
  23. Tse L, Yu I, Qiu H, Au J, Wang X. A case-referent study of lung cancer and incense smoke, smoking, and residential radon in Chinese men. Environ Health Perspect. 2011;119:1641-6 pubmed publisher
    ..Burning incense generates large amounts of air pollutants, many of which are confirmed or suspected human lung carcinogens...
  24. Lantz P, Mendez D, Philbert M. Radon, smoking, and lung cancer: the need to refocus radon control policy. Am J Public Health. 2013;103:443-7 pubmed publisher
    Exposure to radon is the second leading cause of lung cancer, and the risk is significantly higher for smokers than for nonsmokers. More than 85% of radon-induced lung cancer deaths are among smokers...
  25. Janik M, Tokonami S, Kranrod C, Sorimachi A, Ishikawa T, Hosoda M, et al. Comparative analysis of radon, thoron and thoron progeny concentration measurements. J Radiat Res. 2013;54:597-610 pubmed publisher
    This study examined correlations between radon, thoron and thoron progeny concentrations based on surveys conducted in several different countries...
  26. Kataoka T. Study of antioxidative effects and anti-inflammatory effects in mice due to low-dose X-irradiation or radon inhalation. J Radiat Res. 2013;54:587-96 pubmed publisher
    ..This paper reviews new insights into inhibition of ROS-related diseases with low-dose irradiation or radon inhalation. X-irradiation (0...
  27. Cui F, Li J, Chen Q, Du H, Zhang S, Nie J, et al. Radon-induced alterations in micro-RNA expression profiles in transformed BEAS2B cells. J Toxicol Environ Health A. 2013;76:107-19 pubmed publisher
    b>Radon and its progeny are confirmed to be type I carcinogenic agents accounting for increased risks in 10% of observed lung cancers globally. However, the underlying carcinogenic mechanisms are largely unknown...
  28. Turner M, Krewski D, Chen Y, Pope C, Gapstur S, Thun M. Radon and nonrespiratory mortality in the American Cancer Society cohort. Am J Epidemiol. 2012;176:808-14 pubmed publisher
    b>Radon is a known cause of human lung cancer...
  29. Chen J. Canadian lung cancer relative risk from radon exposure for short periods in childhood compared to a lifetime. Int J Environ Res Public Health. 2013;10:1916-26 pubmed publisher
    Long-term exposure to elevated indoor radon concentrations has been determined to be the second leading cause of lung cancer in adults after tobacco smoking...
  30. Kataoka T, Yamato K, Nishiyama Y, Morii Y, Etani R, Takata Y, et al. Comparative study on the inhibitory effects of ?-tocopherol and radon on carbon tetrachloride-induced renal damage. Ren Fail. 2012;34:1181-7 pubmed publisher
    ..attempted to evaluate the quantitative effects of the activation of antioxidative activities in kidney induced by radon inhalation on carbon tetrachloride (CCl4)-induced renal damage. Mice were subjected to intraperitoneal (i.p...
  31. Hauri D, Huss A, Zimmermann F, Kuehni C, Röösli M. A prediction model for assessing residential radon concentration in Switzerland. J Environ Radioact. 2012;112:83-9 pubmed publisher
    Indoor radon is regularly measured in Switzerland. However, a nationwide model to predict residential radon levels has not been developed...
  32. Kavasi N, Kobayashi Y, Kovacs T, Somlai J, Jobbágy V, Nagy K, et al. Effect of radon measurement methods on dose estimation. Radiat Prot Dosimetry. 2011;145:224-32 pubmed publisher
    Different radon measurement methods were applied in the old and new buildings of the Turkish bath of Eger, Hungary, in order to elaborate a radon measurement protocol...
  33. Chen J, Moir D, Whyte J. Canadian population risk of radon induced lung cancer: a re-assessment based on the recent cross-Canada radon survey. Radiat Prot Dosimetry. 2012;152:9-13 pubmed publisher
    Exposure to indoor radon has been determined to be the second leading cause of lung cancer after tobacco smoking...
  34. Kavasi N, Kovacs T, Somlai J, Jobbágy V, Nagy K, Deak E, et al. Comparison of urinary excretion of radon from the human body before and after radon bath therapy. Radiat Prot Dosimetry. 2011;146:27-30 pubmed publisher
    Theoretically, the human body absorbs radon through the lungs and the skin and excretes it through the lungs and the excretory organs during radon bath therapy...
  35. Fornalski K, Dobrzyński L. Pooled Bayesian analysis of twenty-eight studies on radon induced lung cancers. Health Phys. 2011;101:265-73 pubmed publisher
  36. Appleton J, Miles J. A statistical evaluation of the geogenic controls on indoor radon concentrations and radon risk. J Environ Radioact. 2010;101:799-803 pubmed publisher
    ANOVA is used to show that approximately 25% of the total variation of indoor radon concentrations in England and Wales can be explained by the mapped bedrock and superficial geology...
  37. Xu N, Zhang S, Dong L, Nie J, Tong J. Proteomic analysis of lung tissue of rats exposed to cigarette smoke and radon. J Toxicol Environ Health A. 2009;72:752-8 pubmed publisher
    This study examined the protein expression in lung tissues of rats exposed to radon and cigarette smoke using a proteomic approach...
  38. Thompson R, Nelson D, Popkin J, Popkin Z. Case-control study of lung cancer risk from residential radon exposure in Worcester county, Massachusetts. Health Phys. 2008;94:228-41 pubmed publisher
    A study of lung cancer risk from residential radon exposure and its radioactive progeny was performed with 200 cases (58% male, 42% female) and 397 controls matched on age and sex, all from the same health maintenance organization...
  39. Yang Q, Wesch H, Mueller K, Bartsch H, Wegener K, Hollstein M. Analysis of radon-associated squamous cell carcinomas of the lung for a p53 gene hotspot mutation. Br J Cancer. 2000;82:763-6 pubmed
    ..suppressor gene codon 249 arg-->met hotspot mutations, a putative molecular bio-dosimeter of alpha-particle (radon) exposure (Taylor et al (1994) Lancet 343: 86-87; McDonald et al (1995) Cancer Epidemiol Biomarkers Prevent 4: 791-..
  40. Dubois G, Bossew P, Friedmann H. A geostatistical autopsy of the Austrian indoor radon survey (1992-2002). Sci Total Environ. 2007;377:378-95 pubmed
    Indoor radon (Rn) concentrations have been measured intensively in many countries to assess the burden of diseases associated with exposure to this radioactive gas...
  41. Bilban M, Bilban Jakopin C, Vrhovec S. Incidence of chromosomal aberrations and micronuclei in cave tour guides. Neoplasma. 2001;48:278-84 pubmed
    ..Measurements of radon and its daughters were performed at different locations in the cave...
  42. Duport P. Is the radon risk overestimated? Neglected doses in the estimation of the risk of lung cancer in uranium underground miners. Radiat Prot Dosimetry. 2002;98:329-38 pubmed
    Only the exposure to inhaled radon decay products is usually taken into account in the determination of the risk of radiogenic lung cancer in uranium miners...
  43. Bergdahl I, Jonsson H, Eriksson K, Damber L, Jarvholm B. Lung cancer and exposure to quartz and diesel exhaust in Swedish iron ore miners with concurrent exposure to radon. Occup Environ Med. 2010;67:513-8 pubmed publisher
    Studies of underground miners have documented an increased risk of lung cancer mainly linked to radon exposure but possibly influenced by other concurrent exposures.
  44. Haucke F. The cost effectiveness of radon mitigation in existing German dwellings--a decision theoretic analysis. J Environ Manage. 2010;91:2263-74 pubmed publisher
    b>Radon is a naturally occurring inert radioactive gas found in soils and rocks that can accumulate in dwellings, and is associated with an increased risk of lung cancer...
  45. Bossew P. Radon: exploring the log-normal mystery. J Environ Radioact. 2010;101:826-34 pubmed publisher
    ..2006) for the so far unexplained observation that indoor radon concentration data from geographical surveys very often appear to be quite accurately log-normally distributed...
  46. Puskin J. Smoking as a confounder in ecologic correlations of cancer mortality rates with average county radon levels. Health Phys. 2003;84:526-32 pubmed
    Cohen has reported a negative correlation between lung cancer mortality and average radon levels by county. In this paper, the correlation of U.S...
  47. Gerken M, Kreienbrock L, Wellmann J, Kreuzer M, Wichmann H. Models for retrospective quantification of indoor radon exposure in case-control studies. Health Phys. 2000;78:268-78 pubmed
    In epidemiologic studies on lung cancer risk due to indoor radon the quantification of individual radon exposure over a long time period is one of the main issues...
  48. D Alessandro W, Vita F. Groundwater radon measurements in the Mt. Etna area. J Environ Radioact. 2003;65:187-201 pubmed
    b>Radon levels were measured in 119 groundwater samples collected throughout the active volcanic area of Mt. Etna by means of a portable Lucas-type scintillation chamber. The measured activity values range from 1.8 to 52.7 Bq l(-1)...
  49. Pawel D, Puskin J. The U.S. Environmental Protection Agency's assessment of risks from indoor radon. Health Phys. 2004;87:68-74 pubmed
    The U.S. Environmental Protection Agency has updated its assessment of health risks from indoor radon, which has been determined to be the second leading cause of lung cancer after cigarette smoking...
  50. Kaiser J, Heidenreich W, Monchaux G, Morlier J, Collier C. Lung tumour risk in radon-exposed rats from different experiments: comparative analysis with biologically based models. Radiat Environ Biophys. 2004;43:189-201 pubmed
    Data sets of radon-exposed male rats from Wistar and Sprague-Dawley strains have been investigated with two different versions of the two-step clonal expansion (TSCE) model of carcinogenesis...
  51. Bilban M, Jakopin C. Incidence of cytogenetic damage in lead-zinc mine workers exposed to radon. Mutagenesis. 2005;20:187-91 pubmed
    ..damage in mine workers working in a lead-zinc mine, which could be associated with a combined exposure to radon and heavy metals. Our study involved 70 mine workers from the lead-zinc mine...
  52. Charles M. Radon exposure of the skin: II. Estimation of the attributable risk for skin cancer incidence. J Radiol Prot. 2007;27:253-74 pubmed
    ..the various factors which form the chain of assumptions that are necessary to support a suggested link between radon exposure and skin cancer in man...
  53. Kennedy C, Gray A, Denman A, Phillips P. A cost-effectiveness analysis of a residential radon remediation programme in the United Kingdom. Br J Cancer. 1999;81:1243-7 pubmed
    As residential radon programmes of identification and remediation have proceeded, so questions have been raised about their costs and benefits...