Summary: Negatively charged atoms, radicals or groups of atoms which travel to the anode or positive pole during electrolysis.

Top Publications

  1. Zhu B, Kan H, Liu J, Liu H, Wei Q, Du B. A highly selective ratiometric visual and red-emitting fluorescent dual-channel probe for imaging fluoride anions in living cells. Biosens Bioelectron. 2014;52:298-303 pubmed publisher
    ..Finally, the results of its application to bioimaging of F(-) in living cells show that probe 1 would be of great benefit to biomedical researchers for investigating the effects of fluoride in biological systems...
  2. Yang D, Liu H, Liu L, Sarina S, Zheng Z, Zhu H. Silver oxide nanocrystals anchored on titanate nanotubes and nanofibers: promising candidates for entrapment of radioactive iodine anions. Nanoscale. 2013;5:11011-8 pubmed publisher
    ..In this study, a new adsorbent structure with the potential to efficiently remove radioactive iodine anions (I(-)) from water is devised: silver oxide (Ag2O) nanocrystals firmly anchored on the surface of titanate ..
  3. Dutt S, Wilch C, Gersthagen T, Talbiersky P, Bravo Rodriguez K, Hanni M, et al. Molecular tweezers with varying anions: a comparative study. J Org Chem. 2013;78:6721-34 pubmed publisher
    ..The combination of experiment and theory provides deep insight into the host-guest binding modes, a prerequisite to understanding the exciting influence of these tweezers on the aggregation of proteins and the activity of enzymes. ..
  4. Cheng W, D Avanzo N, Doyle D, Nichols C. Dual-mode phospholipid regulation of human inward rectifying potassium channels. Biophys J. 2011;100:620-628 pubmed publisher
    ..In conclusion, we utilized purified proteins in defined lipid membranes to quantitatively determine the phospholipid requirements for human Kir channel activity. ..
  5. Brown R, Edwards P. Measurement of anions in ambient particulate matter by ion chromatography: a novel sample preparation technique and development of a generic uncertainty budget. Talanta. 2009;80:1020-4 pubmed publisher
    A novel sample preparation technique for the measurement of anions in particulate matter by ion chromatography is presented...
  6. Steinberg B, Huynh K, Brodovitch A, Jabs S, Stauber T, Jentsch T, et al. A cation counterflux supports lysosomal acidification. J Cell Biol. 2010;189:1171-86 pubmed publisher
    ..Replacement of cytosolic Cl(-) with impermeant anions did not significantly alter proton pumping, while the presence of permeant cations in the lysosomal lumen ..
  7. Zhang Y, Cremer P. Chemistry of Hofmeister anions and osmolytes. Annu Rev Phys Chem. 2010;61:63-83 pubmed publisher
    ..Here, we review recent studies of the interactions between anions and urea with model macromolecular systems...
  8. Chahine S, O Donnell M. Effects of acute or chronic exposure to dietary organic anions on secretion of methotrexate and salicylate by Malpighian tubules of Drosophila melanogaster larvae. Arch Insect Biochem Physiol. 2010;73:128-47 pubmed publisher
    The effects of dietary exposure to organic anions on the physiology of isolated Malpighian tubules and on tubule gene expression were examined using larvae of Drosophila melanogaster...
  9. Matta C, Arabi A, Weaver D. The bioisosteric similarity of the tetrazole and carboxylate anions: clues from the topologies of the electrostatic potential and of the electron density. Eur J Med Chem. 2010;45:1868-72 pubmed publisher
    ..It is shown that tetrazole and carboxylate anions give rise to electrostatic potentials (ESP) that exhibit a remarkable local similarity in the disposition of four ..

More Information


  1. Moore B, Sun Q, Hsu J, Lee A, Yoo G, Ly T, et al. Dissociation chemistry of hydrogen-deficient radical peptide anions. J Am Soc Mass Spectrom. 2012;23:460-8 pubmed publisher
    ..Possible mechanisms that might account for this novel collision-induced electron detachment are discussed...
  2. Otón F, Espinosa A, Tarraga A, Ratera I, Wurst K, Veciana J, et al. Mononuclear ferrocenophane structural motifs with two thiourea arms acting as a dual binding site for anions and cations. Inorg Chem. 2009;48:1566-76 pubmed publisher
    ..of the redox active ferrocene unit and the thiourea bridges, which unexpectedly act as a dual binding site for anions and metal ions...
  3. Du Q, Fan X, Wang C, Huang R. A possible CO2 conducting and concentrating mechanism in plant stomata SLAC1 channel. PLoS ONE. 2011;6:e24264 pubmed publisher
    ..Based on the SLAC1 structure a theoretical model is derived to illustrate the activation of bicarbonate to SLAC1 channel. Meanwhile a possible CO(2) conducting and concentrating mechanism of the SLAC1 is proposed...
  4. Innocenti A, Scozzafava A, Supuran C. Carbonic anhydrase inhibitors. Inhibition of transmembrane isoforms IX, XII, and XIV with less investigated anions including trithiocarbonate and dithiocarbamate. Bioorg Med Chem Lett. 2010;20:1548-50 pubmed publisher
    ..2.1.1) isoforms IX, XII (tumor-associated), and XIV with anions such as stannate(IV), selenate(VI), tellurate(VI), perosmate(VIII), persulfate, pyrophosphate(V), pyrovanadate(V), ..
  5. Heller J, Elgabarty H, Zhuang B, Sebastiani D, Hinderberger D. Solvation of small disulfonate anions in water/methanol mixtures characterized by high-field pulse electron nuclear double resonance and molecular dynamics simulations. J Phys Chem B. 2010;114:7429-38 pubmed publisher
    ..In particular, this includes the potential perturbation of the H-bond network due to the presence of a spin probe or other polar molecules...
  6. Gardner M, Li N, Ellington A, Brodbelt J. Infrared multiphoton dissociation of small-interfering RNA anions and cations. J Am Soc Mass Spectrom. 2010;21:580-91 pubmed publisher
    ..The single-strand siRNA anions were observed to dissociate via cleavage of the 5' P-O bonds yielding c- and y-type product ions as well as ..
  7. Rokitskaya T, Sumbatyan N, Tashlitsky V, Korshunova G, Antonenko Y, Skulachev V. Mitochondria-targeted penetrating cations as carriers of hydrophobic anions through lipid membranes. Biochim Biophys Acta. 2010;1798:1698-706 pubmed publisher
    ..In particular, the leakage of CF was maximal at n about 10-12 and substantially decreased at n=16. Organic anions (palmitate, oleate, laurylsulfate) competed with CF for the penetrating cation-induced efflux...
  8. Markiewicz M, Piszora M, Caicedo N, Jungnickel C, Stolte S. Toxicity of ionic liquid cations and anions towards activated sewage sludge organisms from different sources -- consequences for biodegradation testing and wastewater treatment plant operation. Water Res. 2013;47:2921-8 pubmed publisher
    ..The inhibitory potential of tested ILs substituted with short alkyl chains (? 4) and polar anions was low...
  9. Vullo D, Nishimori I, Minakuchi T, Scozzafava A, Supuran C. Inhibition studies with anions and small molecules of two novel ?-carbonic anhydrases from the bacterial pathogen Salmonella enterica serovar Typhimurium. Bioorg Med Chem Lett. 2011;21:3591-5 pubmed publisher
    ..2×10(7) M(-1) s(-1) and of 8.3×10(7) M(-1) s(-1), respectively. A large number of simple/complex inorganic anions as well as other small molecules (sulfamide, sulfamic acid, phenylboronic acid, phenylarsonic acid, ..
  10. Brotherhood P, Davis A. Steroid-based anion receptors and transporters. Chem Soc Rev. 2010;39:3633-47 pubmed publisher
    ..principle that discrimination improves with binding strength, and showing good enantioselectivities with chiral anions. The binding strength of cholapods and related systems allows them to act as transmembrane anion carriers...
  11. Hussain S, Brotherhood P, Judd L, Davis A. Diaxial diureido decalins as compact, efficient, and tunable anion transporters. J Am Chem Soc. 2011;133:1614-7 pubmed publisher
    ..Transport rates depend on both NHAr and the alkyl side chain. High activities can be achieved; with optimal substitution, chloride-nitrate exchange across vesicle membranes is measurable at transporter/lipid ratios as low as 1:250,000...
  12. Diaz Espinoza R, Mukherjee A, Soto C. Kosmotropic anions promote conversion of recombinant prion protein into a PrPSc-like misfolded form. PLoS ONE. 2012;7:e31678 pubmed publisher
    ..of protease resistant-recPrP was time and salt-concentration dependent and required the presence of kosmotropic anions such as F(-) or SO(4)(-2)...
  13. Bergsdorf E, Zdebik A, Jentsch T. Residues important for nitrate/proton coupling in plant and mammalian CLC transporters. J Biol Chem. 2009;284:11184-93 pubmed publisher
    ..Gating and proton glutamates play similar roles in bacterial, plant, and mammalian CLC anion/proton exchangers...
  14. Gale P, Tong C, Haynes C, Adeosun O, Gross D, Karnas E, et al. Octafluorocalix[4]pyrrole: a chloride/bicarbonate antiport agent. J Am Chem Soc. 2010;132:3240-1 pubmed publisher
    ..This is the first example of a synthetic macrocyclic pyrrole-based receptor capable of transmembrane bicarbonate transport...
  15. Guo W, Lau K, Fung Y. Microfluidic chip-capillary electrophoresis for two orders extension of adjustable upper working range for profiling of inorganic and organic anions in urine. Electrophoresis. 2010;31:3044-52 pubmed publisher
    To meet the need for onsite monitoring of urine anions, a microfluidic chip-capillary electrophoresis device was designed, fabricated and tested to extend the upper CE working range for an enhancement up to 500 fold (100 fold for sample ..
  16. Mauracher A, Denifl S, Edtbauer A, Hager M, Probst M, Echt O, et al. Metastable anions of dinitrobenzene: resonances for electron attachment and kinetic energy release. J Chem Phys. 2010;133:244302 pubmed publisher
    ..of free, low-energy electrons to dinitrobenzene (DNB) in the gas phase leads to DNB(-) as well as several fragment anions. DNB(-), (DNB-H)(-), (DNB-NO)(-), (DNB-2NO)(-), and (DNB-NO(2))(-) are found to undergo metastable (unimolecular) ..
  17. Chisari M, Wu K, Zorumski C, Mennerick S. Hydrophobic anions potently and uncompetitively antagonize GABA(A) receptor function in the absence of a conventional binding site. Br J Pharmacol. 2011;164:667-80 pubmed publisher
    ..To gain new insights, we tested two structurally unrelated hydrophobic anions with superficially similar properties to sulphated neurosteroids.
  18. Isik S, Kockar F, Arslan O, Guler O, Innocenti A, Supuran C. Carbonic anhydrase inhibitors. Inhibition of the beta-class enzyme from the yeast Saccharomyces cerevisiae with anions. Bioorg Med Chem Lett. 2008;18:6327-31 pubmed publisher
    ..cloned, purified, characterized kinetically, and investigated for its inhibition with a series simple, inorganic anions such as halogenides, pseudohalogenides, bicarbonate, carbonate, nitrate, nitrite, hydrogen sulfide, bisulfite, ..
  19. Gaya U, Abdullah A, Zainal Z, Hussein M. Photocatalytic treatment of 4-chlorophenol in aqueous ZnO suspensions: intermediates, influence of dosage and inorganic anions. J Hazard Mater. 2009;168:57-63 pubmed publisher
    ..The addition of small amounts of inorganic anions as SO(4)(2-), HPO(4)(-), S(2)O(8)(2-) and Cl(-) revealed two anion types: active site blockers and rate enhancers...
  20. Picollo A, Malvezzi M, Houtman J, Accardi A. Basis of substrate binding and conservation of selectivity in the CLC family of channels and transporters. Nat Struct Mol Biol. 2009;16:1294-301 pubmed publisher
    ..We propose that CLC-ec1 operates through an affinity-switch mechanism and that the bases of substrate specificity are conserved in the CLC channels and transporters...
  21. Steed J. Coordination and organometallic compounds as anion receptors and sensors. Chem Soc Rev. 2009;38:506-19 pubmed publisher
    ..The use of anion binding coordination polymer systems in anion separations and in supramolecular gels is also examined...
  22. MacLean D, Wong A, Fay A, Bowie D. Cations but not anions regulate the responsiveness of kainate receptors. J Neurosci. 2011;31:2136-44 pubmed publisher
    ..glutamate receptors are unique among ligand-gated ion channels in their obligate requirement of external anions and cations for activation...
  23. Soga T, Igarashi K, Ito C, Mizobuchi K, Zimmermann H, Tomita M. Metabolomic profiling of anionic metabolites by capillary electrophoresis mass spectrometry. Anal Chem. 2009;81:6165-74 pubmed publisher
    ..The material of the spray needle had significant effect on the measurement of anions. A stainless steel spray needle was oxidized and corroded at the anodic electrode due to electrolysis...
  24. Chawla L, Shih S, Davison D, Junker C, Seneff M. Anion gap, anion gap corrected for albumin, base deficit and unmeasured anions in critically ill patients: implications on the assessment of metabolic acidosis and the diagnosis of hyperlactatemia. BMC Emerg Med. 2008;8:18 pubmed publisher
    ..We set out to determine if these tools can diagnose the presence of HL using cotemporaneous samples...
  25. Maresca A, Scozzafava A, Kohler S, Winum J, Supuran C. Inhibition of beta-carbonic anhydrases from the bacterial pathogen Brucella suis with inorganic anions. J Inorg Biochem. 2012;110:36-9 pubmed publisher
    ..Here we report the inhibition of these two CAs by inorganic and complex anions and other molecules interacting with zinc proteins, such as sulfamide, sulfamic acid, and phenylboronic/arsonic ..
  26. Tripkovic D, Strmcnik D, Van Der Vliet D, Stamenkovic V, Markovic N. The role of anions in surface electrochemistry. Faraday Discuss. 2008;140:25-40; discussion 93-112 pubmed
    ..understanding in the surface electrochemistry are discussed, with emphases on the role of specifically adsorbing anions in hydrogen adsorption and oxide formation, adsorption and ordering of molecular adsorbates and metal ions, metal ..
  27. Gruber B, Ryan P, Richardson A, Tyerman S, Ramesh S, Hebb D, et al. HvALMT1 from barley is involved in the transport of organic anions. J Exp Bot. 2010;61:1455-67 pubmed publisher
    ..conferred both inward and outward currents when expressed in Xenopus laevis oocytes that were bathed in a range of anions including malate...
  28. Alcaraz A, Nestorovich E, López M, García Giménez E, Bezrukov S, Aguilella V. Diffusion, exclusion, and specific binding in a large channel: a study of OmpF selectivity inversion. Biophys J. 2009;96:56-66 pubmed publisher
    ..The elucidation of these factors is essential for understanding large channel selectivity and its regulation in vivo...
  29. Madsen J, Kaoud T, Dalby K, Brodbelt J. 193-nm photodissociation of singly and multiply charged peptide anions for acidic proteome characterization. Proteomics. 2011;11:1329-34 pubmed publisher
    193-nm ultraviolet photodissociation (UVPD) was implemented to sequence singly and multiply charged peptide anions. Upon dissociation by this method, a-/x-type, followed by d and w side-chain loss ions, were the most prolific and abundant ..
  30. Sabirov R, Okada Y. The maxi-anion channel: a classical channel playing novel roles through an unidentified molecular entity. J Physiol Sci. 2009;59:3-21 pubmed publisher
    ..3 nm and permits passage not only of Cl(-) but also of some intracellular large organic anions, thereby releasing major extracellular signals and gliotransmitters such as glutamate(-) and ATP(4-)...
  31. Watt M, Collins M, Johnson D. Ion-? interactions in ligand design for anions and main group cations. Acc Chem Res. 2013;46:955-66 pubmed publisher
    ..This type of interaction could offer new selectivity in binding poorly basic, strongly solvated anions and may also affect structure, biological function, and anion transport...
  32. Yin Z, Wang Q, Zeng M. Iodine release and recovery, influence of polyiodide anions on electrical conductivity and nonlinear optical activity in an interdigitated and interpenetrated bipillared-bilayer metal-organic framework. J Am Chem Soc. 2012;134:4857-63 pubmed publisher
    ..template, consists of a cationic framework with two types of zigzag channels, which segregate I5(–) and I7(–) anions. The framework exhibits the first observed bipillared-bilayer structure featuring both interdigitation and ..
  33. Khansaheb M, Choi J, Joo N, Yang Y, Krouse M, Wine J. Properties of substance P-stimulated mucus secretion from porcine tracheal submucosal glands. Am J Physiol Lung Cell Mol Physiol. 2011;300:L370-9 pubmed publisher
    ..These and prior results suggest that SubP stimulates pig gland secretion via CFTR- and Ca(2+)-activated Cl(-) channels...
  34. Innocenti A, Leewattanapasuk W, Muhlschlegel F, Mastrolorenzo A, Supuran C. Carbonic anhydrase inhibitors. Inhibition of the beta-class enzyme from the pathogenic yeast Candida glabrata with anions. Bioorg Med Chem Lett. 2009;19:4802-5 pubmed publisher
    ..was cloned, purified, characterized kinetically and investigated for its inhibition by a series simple, inorganic anions such as halogenides, pseudohalogenides, bicarbonate, carbonate, nitrate, nitrite, hydrogen sulfide, bisulfite, ..
  35. Wilson D, Abbas M, Radwan A, del Valle M. Potentiometric electronic tongue to resolve mixtures of sulfide and perchlorate anions. Sensors (Basel). 2011;11:3214-26 pubmed publisher
  36. Huang S, Hainzl T, Grundström C, Forsman C, Samuelsson G, Sauer Eriksson A. Structural studies of ?-carbonic anhydrase from the green alga Coccomyxa: inhibitor complexes with anions and acetazolamide. PLoS ONE. 2011;6:e28458 pubmed publisher
  37. Hernández Muñoz L, Gómez M, González F, Gonzalez I, Frontana C. Towards a molecular-level understanding of the reactivity differences for radical anions of juglone and plumbagin: an electrochemical and spectroelectrochemical approach. Org Biomol Chem. 2009;7:1896-903 pubmed publisher
    ..and spectroelectrochemical strategy is presented for evaluating reactivity differences in the semiquinone anions from naturally occurring quinones juglone (5-hydroxy-1,4-naphthoquinone) and plumbagin (2-methyl-5-hydroxy-1,4-..
  38. Han L, Hyung S, Mayers J, Ruotolo B. Bound anions differentially stabilize multiprotein complexes in the absence of bulk solvent. J Am Chem Soc. 2011;133:11358-67 pubmed publisher
    ..dissociation and unfolding transitions for four tetrameric protein complexes bound to populations of 12 different anions using collisional activation...
  39. Marques da Silva C, Chaves M, Rodrigues J, Corte Real S, Coutinho Silva R, Persechini P. Differential modulation of ATP-induced P2X7-associated permeabilities to cations and anions of macrophages by infection with Leishmania amazonensis. PLoS ONE. 2011;6:e25356 pubmed publisher
    ..the phenomenon of macrophage membrane permeabilization can involve at least two distinct pathways for cations and anions respectively...
  40. Mareda J, Matile S. Anion-pi slides for transmembrane transport. Chemistry. 2009;15:28-37 pubmed publisher
    The recognition and transport of anions is usually accomplished by hydrogen bonding, ion pairing, metal coordination, and anion-dipole interactions. Here, we elaborate on the concept to use anion-pi interactions for this purpose...
  41. Révész A, Schröder D, Svec J, Wimmerova M, Sindelar V. Anion binding by bambus[6]uril probed in the gas phase and in solution. J Phys Chem A. 2011;115:11378-86 pubmed publisher
    Electrospray ionization mass spectrometry (ESI-MS) is used to probe the binding of small anions to the macrocycle of bambus[6]uril...
  42. Wu B, Yang J, Huang X, Li S, Jia C, Yang X, et al. Anion binding by metallo-receptors of 5,5'-dicarbamate-2,2'-bipyridine ligands. Dalton Trans. 2011;40:5687-96 pubmed publisher
    ..Interestingly, the carbamate functionalities are involved in hydrogen bonding with various guests (anions or solvents), especially in the tris(chelate) complexes which feature the well-organized C(3)-clefts for effective ..
  43. Wang H, Malhotra S, Francis A. Toxicity of various anions associated with methoxyethyl methyl imidazolium-based ionic liquids on Clostridium sp. Chemosphere. 2011;82:1597-603 pubmed publisher
    ..These anions, in association with [MOEMIM](+) lowered the growth rate of the bacterium, showing the following trend: [Tf?N]? ? [..
  44. Kanawati B, Schmitt Kopplin P. Exploring rearrangements along the fragmentation of glutaric acid negative ion: a combined experimental and theoretical study. Rapid Commun Mass Spectrom. 2010;24:1198-206 pubmed publisher
    ..The DFT study also reveals that a combined loss of CO2 and H2O in the form of H2CO3 is possible...
  45. Huzarska M, Ugalde I, Kaplan D, Hartmer R, Easterling M, Polfer N. Negative electron transfer dissociation of deprotonated phosphopeptide anions: choice of radical cation reagent and competition between electron and proton transfer. Anal Chem. 2010;82:2873-8 pubmed publisher
    ..spectrometry technology in recent years, no routine proteomics sequencing tool is currently available for peptide anions. The use of a molecular open-shell cation is presented here as a possible reaction partner to induce electron ..
  46. Weinhart M, Gröger D, Enders S, Dernedde J, Haag R. Synthesis of dendritic polyglycerol anions and their efficiency toward L-selectin inhibition. Biomacromolecules. 2011;12:2502-11 pubmed publisher
    ..1,3-dipolar cycloaddition ("click-reaction") of polyglycerolazide precursors and alkyne-functionalized anions such as sulfonates, carboxylates, phosphonates, and bisphosphonates...
  47. Xue S, Hu H, Ries A, Merilo E, Kollist H, Schroeder J. Central functions of bicarbonate in S-type anion channel activation and OST1 protein kinase in CO2 signal transduction in guard cell. EMBO J. 2011;30:1645-58 pubmed publisher
    ..A new working model of the sequence of CO(2) signalling events in gas exchange regulation is presented...
  48. Yang L, Jiang H, Tang N, Chen L. Mechanisms of aluminum-tolerance in two species of citrus: secretion of organic acid anions and immobilization of aluminum by phosphorus in roots. Plant Sci. 2011;180:521-30 pubmed publisher
    ..The higher Al-tolerance of C. sinensis may involve secretion of OA anions and precipitation of Al by P in roots.
  49. Moragues M, Martínez Máñez R, Sancenon F. Chromogenic and fluorogenic chemosensors and reagents for anions. A comprehensive review of the year 2009. Chem Soc Rev. 2011;40:2593-643 pubmed publisher
    This critical review is focused on examples reported in the year 2009 dealing with the design of chromogenic and fluorogenic chemosensors or reagents for anions (264 references).
  50. Davis J, Okunola O, Quesada R. Recent advances in the transmembrane transport of anions. Chem Soc Rev. 2010;39:3843-62 pubmed publisher
    b>Anions cannot diffuse passively through biological membranes and membrane-bound proteins mainly govern the transmembrane movement of these charged species...
  51. Oomens J, Steill J, Redlich B. Gas-phase IR spectroscopy of deprotonated amino acids. J Am Chem Soc. 2009;131:4310-9 pubmed publisher
    ..In sharp contrast with the conjugate bases of other amino acids investigated here, the aspartate and glutamate anions show very broad, hardly resolved spectral features...
  52. Berezin S, Davis J. Catechols as membrane anion transporters. J Am Chem Soc. 2009;131:2458-9 pubmed publisher
    ..This assay reveals that anion transport selectivity for this amphiphilic bis-catechol follows a Hofmeister sequence wherein anions that are easier to dehydrate are made more permeable to the membrane by 3.
  53. McNally B, O Neil E, Nguyen A, Smith B. Membrane transporters for anions that use a relay mechanism. J Am Chem Soc. 2008;130:17274-5 pubmed publisher
    ..The expected favorable formulation properties of these amphiphilic compounds should facilitate efforts to transform them into tools for biomedical research and perhaps as therapeutic agents...