Summary: Negative ions or salts derived from bromic acid, HBrO3.

Top Publications

  1. Chipman J, Davies J, Parsons J, Nair J, O NEILL G, Fawell J. DNA oxidation by potassium bromate; a direct mechanism or linked to lipid peroxidation?. Toxicology. 1998;126:93-102 pubmed
    ..The results do not support a role, in rat kidney, of a direct, GSH-mediated mechanism for KBrO3-induced DNA oxidation as seen in vitro...
  2. Crosby L, Hyder K, DeAngelo A, Kepler T, Gaskill B, Benavides G, et al. Morphologic analysis correlates with gene expression changes in cultured F344 rat mesothelial cells. Toxicol Appl Pharmacol. 2000;169:205-21 pubmed
  3. Murata M, Bansho Y, Inoue S, Ito K, Ohnishi S, Midorikawa K, et al. Requirement of glutathione and cysteine in guanine-specific oxidation of DNA by carcinogenic potassium bromate. Chem Res Toxicol. 2001;14:678-85 pubmed
  4. Young Y, Chuu J, Liu S, Lin Shiau S. Toxic effects of potassium bromate and thioglycolate on vestibuloocular reflex systems of Guinea pigs and humans. Toxicol Appl Pharmacol. 2001;177:103-11 pubmed
    ..Our clinical findings together with the animal study imply that clinicians should be alert to the risk of bromate exposure in hairdressers, especially those with vertigo, tinnitus, or hearing loss...
  5. Umemura T, Kitamura Y, Kanki K, Maruyama S, Okazaki K, Imazawa T, et al. Dose-related changes of oxidative stress and cell proliferation in kidneys of male and female F344 rats exposed to potassium bromate. Cancer Sci. 2004;95:393-8 pubmed
    ..These findings suggest that DNA oxidation induced by KBrO3 may occur independently of lipid peroxidation and more than 250 ppm KBrO3 in the drinking water can exert a carcinogenic effect by way of oxidative stress...
  6. Ballmaier D, Epe B. DNA damage by bromate: mechanism and consequences. Toxicology. 2006;221:166-71 pubmed
  7. Uchida H, Sugiyama H, Kanehisa S, Harada K, Fujiwara K, Ono T, et al. An elderly patient with severe acute renal failure due to sodium bromate intoxication. Intern Med. 2006;45:151-4 pubmed
    ..To the best of our knowledge this is the first report of an elderly patient that demonstrates the clinical benefit of hemodialysis therapy for bromate intoxication...
  8. Crofton K. Bromate: concern for developmental neurotoxicity?. Toxicology. 2006;221:212-6 pubmed
    ..These studies would provide invaluable data for the weight-of-evidence approach used to determine the necessity of a developmental neurotoxicity study of bromate...
  9. Zhang X, De Silva D, Sun B, Fisher J, Bull R, Cotruvo J, et al. Cellular and molecular mechanisms of bromate-induced cytotoxicity in human and rat kidney cells. Toxicology. 2010;269:13-23 pubmed publisher
    ..The similar mode of action in both NRK and HEK293 cells suggests that the mechanisms of BrO(3)(-)-induced renal cell death are model-independent...

More Information

Publications108 found, 100 shown here

  1. Wolf D, Crosby L, George M, Kilburn S, Moore T, Miller R, et al. Time- and dose-dependent development of potassium bromate-induced tumors in male Fischer 344 rats. Toxicol Pathol. 1998;26:724-9 pubmed
    ..1- and 0.2-g/L groups. The present study can be used as a basis for the determination of dose-time relationships of tumor development for a better understanding of KBrO3-induced cancer...
  2. Farombi E, Alabi M, Akuru T. Kolaviron modulates cellular redox status and impairment of membrane protein activities induced by potassium bromate (KBrO(3)) in rats. Pharmacol Res. 2002;45:63-8 pubmed
    ..Kolaviron may therefore intervene in the cellular redox status and depression of membrane protein activities caused by KBrO(3)and other environmental carcinogens in the kidney...
  3. Ensafi A, Rezaei B, Movahedinia H. Kinetic-spectrophotometric determination of ascorbic acid by inhibition of the hydrochloric acid-bromate reaction. Spectrochim Acta A Mol Biomol Spectrosc. 2002;58:2589-94 pubmed
    ..8 and 1.7%, respectively. The influence of potential interfering substance was studied. The method was successfully applied for the determination of ascorbic acid in pharmaceuticals. ..
  4. Juknelevicius D, Karvinen E, Klapötke T, Kubilius R, Ramanavicius A, Rusan M. Copper(I) Bromide: An Alternative Emitter for Blue-Colored Flame Pyrotechnics. Chemistry. 2015;21:15354-9 pubmed publisher
    ..Pyrotechnic compositions, which contained copper and potassium bromates as oxidizers, were optimized for the generation of blue flames...
  5. Campbell K. Bromate-induced ototoxicity. Toxicology. 2006;221:205-11 pubmed
    ..Further study to determine the maximum safe exposure level for long-term administration and to develop possible antidotes is warranted. ..
  6. Quiñones O, Snyder S, Cotruvo J, Fisher J. Analysis of bromate and bromide in blood. Toxicology. 2006;221:229-34 pubmed
  7. Werschkun B, Sommer Y, Banerji S. Disinfection by-products in ballast water treatment: an evaluation of regulatory data. Water Res. 2012;46:4884-901 pubmed publisher
    ..This concerns the extent and statistical characterisation of chemical analysis as well as the documentation of the test water parameters. ..
  8. Nakata S, Morishima S, Kitahata H. Interactive propagation of photosensitive chemical waves on two circular routes. J Phys Chem A. 2006;110:3633-7 pubmed
    ..These results suggest that the photosensitive BZ reaction may be useful for creating spatiotemporal patterns that depend on the geometric arrangement of excitable fields. ..
  9. Chekanov A, Osipov A, Vladimirov I, Sergienko V, Panasenko O. [A comparative spin trapping study of hypobromous and hypochlorous acids interaction with tert-butyl hydroperoxide]. Biofizika. 2007;52:5-13 pubmed
    ..This reaction can be of great importance in the intensification of free radical processes, namely, in lipid peroxidation at the stage of chain branching. ..
  10. Cooley N, Elder R, Povey A. The effect of Msh2 knockdown on toxicity induced by tert-butyl-hydroperoxide, potassium bromate, and hydrogen peroxide in base excision repair proficient and deficient cells. Biomed Res Int. 2013;2013:152909 pubmed publisher
    ..MSH2 dependent and independent pathways then determine cellular toxicity induced by oxidising agents. A complex interaction between MMR and BER repair systems, that is, exposure dependent, also exists to determine cellular toxicity. ..
  11. Khan N, Sharma S, Sultana S. Nigella sativa (black cumin) ameliorates potassium bromate-induced early events of carcinogenesis: diminution of oxidative stress. Hum Exp Toxicol. 2003;22:193-203 pubmed
    ..001). Data suggest that Nigella sativa is a potent chemopreventive agent and may suppress KBrO3-mediated renal oxidative stress, toxicity and tumour promotion response in rats. ..
  12. Oh B, Oh S, Hwang Y, Yu H, Kang J, Kim I. Formation of hazardous inorganic by-products during electrolysis of seawater as a disinfection process for desalination. Sci Total Environ. 2010;408:5958-65 pubmed publisher
    ..Consequently, it was concluded that the application of the electrochemical process to seawater desalination cannot be recommended without the control of bromate. ..
  13. Al Ansi S, Othman A, Al Tufail M. Bromate pollutant in ozonated bottled Zamzam water from Saudi Arabia determined by LC/ICP-MS. J Environ Sci Health A Tox Hazard Subst Environ Eng. 2011;46:1529-32 pubmed publisher
    ..S. Environmental Protection Agency (U.S. EPA) allowable limit (10 ?g/L) for bromate in bottled drinking water. Bottled drinking water brands, disinfected with ozone showed relatively lower levels of bromate as compared with Zamzam water. ..
  14. Basavaiah K, Nagegowda P. Determination of ranitidine hydrochloride in pharmaceutical preparations by titrimetry and visible spectrophotometry using bromate and acid dyes. Farmaco. 2004;59:147-53 pubmed
    ..The proposed methods were applied successfully to the determination of RNH in tablets and injections. The reliability of the assay was established by parallel determination by the official method and by recovery studies. ..
  15. Limonciel A, Wilmes A, Aschauer L, Radford R, Bloch K, McMorrow T, et al. Oxidative stress induced by potassium bromate exposure results in altered tight junction protein expression in renal proximal tubule cells. Arch Toxicol. 2012;86:1741-51 pubmed publisher
    ..The further understanding of the cross-talk between these two pathways could have major implications for epithelial repair, carcinogenesis and metastasis. ..
  16. Mernyak E, Schönecker B, Lange C, Kötteritzsch M, Görls H, Wolfling J, et al. Addition reactions at the 16(17) double bond of 3-methoxy-13alpha-estra-1,3,5(10),16-tetraene. Steroids. 2003;68:289-95 pubmed
    ..The bromohydrin 5 is the first 13alpha-steroid with a 17beta-bromo substituent. X-ray analysis revealed twist-boat and 16beta-envelope conformations for rings C and D, respectively. ..
  17. Zimmermann S, Wittenwiler M, Hollender J, Krauss M, Ort C, Siegrist H, et al. Kinetic assessment and modeling of an ozonation step for full-scale municipal wastewater treatment: micropollutant oxidation, by-product formation and disinfection. Water Res. 2011;45:605-17 pubmed publisher
    ..5 log units during sand filtration was observed for TCC while no regrowth occurred for E. coli. E. coli inactivation could not be accurately predicted by the model approach, most likely due to shielding of E. coli by flocs. ..
  18. Li J, Zou L, Guo L, Ji J. Pilot study on bromate reduction in ozonation of water with low carbonate alkalinities by carbon dioxide. J Environ Sci (China). 2011;23:1491-6 pubmed
    ..CO2 could be applied through the aeration diffuser together with ozone gas, resulting in a similar bromate reduction compared with the premixing method through Venturi mixer. ..
  19. Wei M, Hamoud A, Yamaguchi T, Kakehashi A, Morimura K, Doi K, et al. Potassium bromate enhances N-ethyl-N-hydroxyethylnitrosamine-induced kidney carcinogenesis only at high doses in Wistar rats: indication of the existence of an enhancement threshold. Toxicol Pathol. 2009;37:983-91 pubmed publisher
    ..Taking account of previous similar findings in male F344 rats, it is strongly suggested that a threshold dose exists for enhancement effects of KBrO(3) on kidney carcinogenesis in rats. ..
  20. Lee N, Patel D, Liu H, Zhang R. Insights from kinetic studies of photo-generated compound II models: Reactivity toward aryl sulfides. J Inorg Biochem. 2018;183:58-65 pubmed publisher three electron-deficient ligands by visible light irradiation of highly photo-labile porphyrin-iron(III) bromates or chlorates...
  21. Hilp M. Identification of lactate. Analytical methods of pharmacopoeias with DBH in respect to environmental and economical concern, Part 4. Pharmazie. 2001;56:548-51 pubmed
    ..According to DAB 2000 the base of ethacridine lactate has to be separated. This is no longer necessary, if an enzymatic identification is applied. ..
  22. Carrasco Turigas G, Villanueva C, Goni F, Rantakokko P, Nieuwenhuijsen M. The effect of different boiling and filtering devices on the concentration of disinfection by-products in tap water. J Environ Public Health. 2013;2013:959480 pubmed publisher
    ..This needs to be considered in the exposure assessment of the epidemiological studies. ..
  23. Kim J, von Gunten U, Mariñas B. Simultaneous prediction of Cryptosporidium parvum oocyst inactivation and bromate formation during ozonation of synthetic waters. Environ Sci Technol. 2004;38:2232-41 pubmed
    ..parvum oocysts by designing ozone reactors with hydrodynamic conditions approaching that of an ideal plug flow reactor and by lowering the pH of the target water. ..
  24. Kujawska M, Ignatowicz E, Ewertowska M, Adamska T, Markowski J, Jodynis Liebert J. Attenuation of KBrO3-induced renal and hepatic toxicity by cloudy apple juice in rat. Phytother Res. 2013;27:1214-9 pubmed publisher
    ..Supplementation with cloudy apple juice to some extent attenuated oxidative damage induced by KBrO3 in the liver and kidney of rats as evidenced by alterations of certain oxidative stress markers and clinical chemistry parameters. ..
  25. Priestley C, Green R, Fellows M, Doherty A, Hodges N, O Donovan M. Anomalous genotoxic responses induced in mouse lymphoma L5178Y cells by potassium bromate. Toxicology. 2010;267:45-53 pubmed publisher
    ..It appears that the responses of L5178Y cells to KBrO3 are complex and differ from those induced by other oxidising agents. ..
  26. Cordeiro F, Robouch P, de la Calle M, Emteborg H, Charoud Got J, Schmitz F. Determination of dissolved bromate in drinking water by ion chromatography and post column reaction: interlaboratory study. J AOAC Int. 2011;94:1592-600 pubmed
    ..It can, therefore, be considered to fit its intended analytical purpose. ..
  27. An X, Zhuo H, Wang Y, Li Q. Competition between hydrogen bonds and halogen bonds in complexes of formamidine and hypohalous acids. J Mol Model. 2013;19:4529-35 pubmed publisher
    ..The structures, properties, and interaction nature in these complexes have been understood with natural bond orbital (NBO) and atoms in molecules (AIM) theories. ..
  28. Speit G, Haupter S, Schutz P, Kreis P. Comparative evaluation of the genotoxic properties of potassium bromate and potassium superoxide in V79 Chinese hamster cells. Mutat Res. 1999;439:213-21 pubmed
    ..Our results suggest that the two oxidizing compounds induce specific patterns of genotoxic effects that reflect the types of DNA alterations induced by different reactive oxygen species (ROS). ..
  29. Allard S, Nottle C, Chan A, Joll C, von Gunten U. Ozonation of iodide-containing waters: selective oxidation of iodide to iodate with simultaneous minimization of bromate and I-THMs. Water Res. 2013;47:1953-60 pubmed publisher
    ..Therefore, in iodide-containing waters, in which I-DBPs can be produced upon chlorination or especially chloramination, a pre-ozonation step to oxidize iodide to iodate is an efficient process to mitigate I-DBP formation...
  30. Perez Ruiz T, Martinez Lozano C, Tomas V, Fenoll J. Spectrofluorimetric determination of formaldehyde by a flow-injection method based on its catalytic effect on the acridine yellow-bromate reaction. Anal Bioanal Chem. 2003;375:661-5 pubmed
    ..The accuracy of the method was confirmed by comparing the results with those obtained using the standard acetylacetone method. ..
  31. Tang G, Adu Sarkodie K, Kim D, Kim J, Teefy S, Shukairy H, et al. Modeling Cryptosporidium parvum oocyst inactivation and bromate formation in a full-scale ozone contactor. Environ Sci Technol. 2005;39:9343-50 pubmed
    ..Additional model simulations revealed that ozone contactors should be designed with the lowest possible backmixing so that the target inactivation efficiency can be achieved with the lowest possible formation of bromate. ..
  32. Kim S, Yamada H, Tsuno H. Ozonation parameter for removal of oestrogenicity from secondary effluent without by-products. Water Sci Technol. 2007;55:233-40 pubmed
    ..1 nM without significant formation of bromate ion, and its value was determined to be 2 (mgO3/mgC) in ozonation of secondary effluent. ..
  33. Mirbahai L, Kershaw R, Green R, Hayden R, Meldrum R, Hodges N. Use of a molecular beacon to track the activity of base excision repair protein OGG1 in live cells. DNA Repair (Amst). 2010;9:144-52 pubmed publisher
    ..In conclusion, these data indicate that the mitochondria are the major site for OGG1 repair activity under conditions of oxidative stress. ..
  34. Zhang Y, Jiang L, Jiang L, Geng C, Li L, Shao J, et al. Possible involvement of oxidative stress in potassium bromate-induced genotoxicity in human HepG2 cells. Chem Biol Interact. 2011;189:186-91 pubmed publisher
    ..These results suggest that PB exerts oxidative stress and genotoxic effects in HepG2 cells, possibly through the mechanisms of lysosomal damage, an earlier event preceding the oxidative DNA damage. ..
  35. Choi J, Kim D, Hyun J, Yoon S, Choi E, Hahm K, et al. Measurement of oxidative damage at individual gene levels by quantitative PCR using 8-hydroxyguanine glycosylase (OGG1). Mutat Res. 2003;523-524:225-35 pubmed
    ..We expect to use this method in studies of carcinogenic mechanism and chemoprevention since it can provide more specific information pertaining to individual genes we are interested in. ..
  36. Kitamaki Y, Takeuchi T. Cyclodextrin-aided determination of iodate and bromate in drinking water by microcolumn ion chromatography with precolumn enrichment. Anal Sci. 2004;20:1399-402 pubmed
    ..Precolumn enrichment improved the detection limit, and allowed the determination of BrO3- in bottled water as low as sub microg L(-1) level in microcolumn IC. ..
  37. Komulainen S, Verlackt C, Pursiainen J, Lajunen M. Oxidation and degradation of native wheat starch by acidic bromate in water at room temperature. Carbohydr Polym. 2013;93:73-80 pubmed publisher
    ..5-2.5% and 1.7-17.2%, respectively, in the product fragments. A mechanism for the oxidation reaction was proposed. ..
  38. Schminke G, Seubert A. Comparison of ion chromatographic methods based on conductivity detection, post-column-reaction and on-line-coupling IC-ICP-MS for the determination of bromate. Fresenius J Anal Chem. 2000;366:387-91 pubmed
    ..The highest amount of information is delivered by IC-PCR-VIS, which allows the simultaneous determination of the seven standard anions and bromate. ..
  39. Rzeszutko W, Apola A. [Spectrophotometric determination of iodide ions in reaction with chloramine T and bromate and bromide ions using amplification procedure]. Rocz Panstw Zakl Hig. 2001;52:353-9 pubmed
    ..There has been developed a method for the quantitative determination of small content of iodide ions making use of amplification reaction with bromine reduced from bromate (V)--bromide system. ..
  40. Kalchayanand N, Koohmaraie M, Wheeler T. Effect of Exposure Time and Organic Matter on Efficacy of Antimicrobial Compounds against Shiga Toxin-Producing Escherichia coli and Salmonella. J Food Prot. 2016;79:561-8 pubmed publisher
    ..These factors should be considered when choosing an antimicrobial compound for an intervention. ..
  41. Shen J, Pullela S, Marquez M, Cheng Z. Ternary phase diagram for the Belousov-Zhabotinsky reaction-induced mechanical oscillation of intelligent PNIPAM colloids. J Phys Chem A. 2007;111:12081-5 pubmed
  42. Hollender J, Zimmermann S, Koepke S, Krauss M, McArdell C, Ort C, et al. Elimination of organic micropollutants in a municipal wastewater treatment plant upgraded with a full-scale post-ozonation followed by sand filtration. Environ Sci Technol. 2009;43:7862-9 pubmed publisher
    ..The energy requirement for the additional post-ozonation step is about 0.035 kWh m(-3), which corresponds to 12% of a typical medium-sized nutrient removal plant (5 g DOC m(-3)). ..
  43. Mally A, Amberg A, Hard G, Dekant W. Are 4-hydroxy-2(E)-nonenal derived mercapturic acids and (1)H NMR metabonomics potential biomarkers of chemically induced oxidative stress in the kidney?. Toxicology. 2007;230:244-55 pubmed
  44. Milikić J, Stoševski I, Krstić J, Kačarević Popović Z, Miljanić S, Sljukić B. Electroanalytical Sensing of Bromides Using Radiolytically Synthesized Silver Nanoparticle Electrocatalysts. J Anal Methods Chem. 2017;2017:2028417 pubmed publisher
    Monitoring bromides (Br-) is of crucial importance since bromates, potential human carcinogens, are formed during ozonation of water containing bromides in concentrations >100??g?L-1...
  45. Kurata Y, Diwan B, Ward J. Lack of renal tumour-initiating activity of a single dose of potassium bromate, a genotoxic renal carcinogen in male F344/NCr rats. Food Chem Toxicol. 1992;30:251-9 pubmed
    ..These results indicate that the KBrO3 dose of 300 mg/kg did not initiate renal carcinogenesis. ..
  46. Bantle J, Finch R, Fort D, Stover E, Hull M, Kumsher King M, et al. Phase III interlaboratory study of FETAX. Part 3. FETAX validation using 12 compounds with and without an exogenous metabolic activation system. J Appl Toxicol. 1999;19:447-72 pubmed
    ..The MAS was essential in using FETAX to predict developmental hazard in mammals, and still requires further development. ..
  47. Vanag V, Epstein I. Pattern formation in a tunable medium: the Belousov-Zhabotinsky reaction in an aerosol OT microemulsion. Phys Rev Lett. 2001;87:228301 pubmed
    ..The variety of patterns is determined by the tunable microstructure of the medium, i.e., by the concentration and size of water droplets. We propose a simple model to describe this system. ..
  48. Shiao Y, Kamata S, Li L, Hooth M, DeAngelo A, Anderson L, et al. Mutations in the VHL gene from potassium bromate-induced rat clear cell renal tumors. Cancer Lett. 2002;187:207-14 pubmed
    ..No VHL mutations were observed in three chromophilic tumors. KBrO(3)-induced rat renal tumors are morphologically similar to their human counterpart but the genetic basis of tumorigenesis is different. ..
  49. Hincha D. Release of two peripheral proteins from chloroplast thylakoid membranes in the presence of a Hofmeister series of chaotropic anions. Arch Biochem Biophys. 1998;358:385-90 pubmed
    ..The addition of sugars (glucose, sucrose, or trehalose) reduced the amount of protein released from the membranes in the presence of NaI or NaSCN...
  50. Cavalli S, Polesello S, Valsecchi S. Chloride interference in the determination of bromate in drinking water by reagent free ion chromatography with mass spectrometry detection. J Chromatogr A. 2005;1085:42-6 pubmed
    ..The effect of the chloride concentration on the detection of bromate is discussed...
  51. Ondrácek J, Mesters J. An ensemble of crystallographic models enables the description of novel bromate-oxoanion species trapped within a protein crystal. Acta Crystallogr D Biol Crystallogr. 2006;62:996-1001 pubmed
    ..For all bromate ions, the main-chain amide atoms of the protein were identified as the dominant binding positions, a useful property in any experimental phase-determination experiment...
  52. Lawal W, Gandhi J, Zhang C. Direct injection, simple and robust analysis of trace-level bromate and bromide in drinking water by IC with suppressed conductivity detection. J Chromatogr Sci. 2010;48:537-43 pubmed
    ..The fact that none of these tap water samples contained bromate (despite an abundance in bromide) proves our hypothesis even further...
  53. Guo Y, Xu F, Meng L, Tang W, Xia Y, Wu Y, et al. Preparation and application of trimethylamine amination polychloromethyl styrene nanolatex coated capillary column for the determination of bromate by field-amplified sample stacking open-tubular capillary electrochromatography. Electrophoresis. 2013;34:1312-8 pubmed publisher
    ..Compared to OT-CEC, the LOD with FASS-OT-CEC was improved from 80 to 8 ng/mL. The developed FASS-OT-CEC method was practically used for the analysis of bromate in tap water samples with recoveries ranging from 93.6 to 103.5%...
  54. Prütz W, Kissner R, Nauser T, Koppenol W. On the oxidation of cytochrome c by hypohalous acids. Arch Biochem Biophys. 2001;389:110-22 pubmed
    ..Iodide also catalyzes methionine sulfoxidation and thiol oxidation by NH2Cl. The possible biological relevance of these findings is discussed...
  55. Roehl R, Slingsby R, Avdalovic N, Jackson P. Applications of ion chromatography with electrospray mass spectrometric detection to the determination of environmental contaminants in water. J Chromatogr A. 2002;956:245-54 pubmed
    ..e. compounds with adverse health effects which are either regulated or being considered for regulation, such as bromate, perchlorate, haloacetic acids, and selenium species, in various water samples...
  56. Xie S, Shi D, Wen D, Wang R, Xi D. Control of bromate and THM precursors using ozonation combined system. Biomed Environ Sci. 2007;20:217-25 pubmed
    ..To investigate the feasibility of reducing THM precursors and controlling bromate taste and odor in drinking water taken from the Yellow River by an ozonation combined system...
  57. Bojic J, Radovanovic B, Dimitrijevic J. Spectrophotometric determination of urea in dermatologic formulations and cosmetics. Anal Sci. 2008;24:769-74 pubmed
    ..The variables affecting the rate of the reaction were investigated. The relative standard deviation for five-replication determination of 60 microg ml(-1) urea was 2.1% and the detection limit of the method is 0.34 ng ml(-1)...
  58. Pisarenko A, Stanford B, Quiñones O, Pacey G, Gordon G, Snyder S. Rapid analysis of perchlorate, chlorate and bromate ions in concentrated sodium hypochlorite solutions. Anal Chim Acta. 2010;659:216-23 pubmed publisher
    ..Malonic acid was chosen as the quenching agent of choice, meeting all evaluation criteria outlined in this manuscript...
  59. Castillo P, Bogliolo M, Surralles J. Coordinated action of the Fanconi anemia and ataxia telangiectasia pathways in response to oxidative damage. DNA Repair (Amst). 2011;10:518-25 pubmed publisher
    ..We conclude that the handling of DNA damage after H(2)O(2)-induced oxidative stress requires the coordinated action of FANCD2 and ATM...
  60. Zakaria P, Bloomfield C, Shellie R, Haddad P, Dicinoski G. Determination of bromate in sea water using multi-dimensional matrix-elimination ion chromatography. J Chromatogr A. 2011;1218:9080-5 pubmed publisher
    ..Recoveries for the three-dimensional system were 92% and 89% based on peak height and area, respectively, taken over 5 ozonated samples with 3 replicates per sample...
  61. Yadav M, Sand A, Behari K. Synthesis and properties of a water soluble graft (chitosan-g-2-acrylamidoglycolic acid) copolymer. Int J Biol Macromol. 2012;50:1306-14 pubmed publisher
    ..The graft copolymer has been characterized by Fourier transform infrared (FTIR) spectroscopy and thermogravimetric analysis...
  62. Fang J, Shang C. Bromate formation from bromide oxidation by the UV/persulfate process. Environ Sci Technol. 2012;46:8976-83 pubmed publisher
    ..The extent of bromate formation and degradation of micropollutants are nevertheless coupled processes unless intermediate bromine species are consumed by NOM in real water...
  63. Suzuta K, Ogawa S, Takeda Y, Kaneyama K, Arai K. Intermolecular disulfide cross-linked structural change induced by permanent wave treatment of human hair with thioglycolic acid. J Cosmet Sci. 2012;63:177-96 pubmed
  64. Kingsbury R, Singer P. Effect of magnetic ion exchange and ozonation on disinfection by-product formation. Water Res. 2013;47:1060-72 pubmed publisher
  65. Ahmad M, Khan A, Mahmood R. Taurine ameliorates potassium bromate-induced kidney damage in rats. Amino Acids. 2013;45:1109-21 pubmed publisher
    ..These results show that taurine is an effective chemoprotectant against bromate-induced renal damage and this amino acid could prove to be useful in attenuating the toxicity of this compound. ..
  66. Bourgin M, Borowska E, Helbing J, Hollender J, Kaiser H, Kienle C, et al. Effect of operational and water quality parameters on conventional ozonation and the advanced oxidation process O3/H2O2: Kinetics of micropollutant abatement, transformation product and bromate formation in a surface water. Water Res. 2017;122:234-245 pubmed publisher
    ..The combined algae assay showed that water quality was significantly improved after oxidation and GAC post-treatment, driven by the abatement of the spiked pesticides (diuron and atrazine). ..
  67. Hawkins C, Davies M. The role of aromatic amino acid oxidation, protein unfolding, and aggregation in the hypobromous acid-induced inactivation of trypsin inhibitor and lysozyme. Chem Res Toxicol. 2005;18:1669-77 pubmed
    ..Decomposition of these species correlates with secondary oxidation reactions, and with lysozyme, a time-dependent loss in activity. Overall, 70% of the HOBr can be accounted for with STI and 95% with lysozyme...
  68. Cantor K. Feasibility of conducting human studies to address bromate risks. Toxicology. 2006;221:197-204 pubmed
    ..Such a study could fill an important data gap by providing human data to help estimate the carcinogenic risk from this exposure...
  69. Fisher J, Bull R. Development of a rat dosimetry model for bromate. Toxicology. 2006;221:235-40 pubmed
    ..The proposed research is expected to be instrumental in quantifying the human health risks associated with ingestion of low levels of bromate in drinking water...
  70. Kitahata H, Yamada A, Nakata S, Ichino T. Propagation of photosensitive chemical waves on the circular routes. J Phys Chem A. 2005;109:4973-8 pubmed
    ..These results suggest that the photosensitive BZ reaction may be useful for creating spatio-temporal patterns depending on the geometric arrangement of excitable fields...
  71. Gerrity D, Mayer B, Ryu H, Crittenden J, Abbaszadegan M. A comparison of pilot-scale photocatalysis and enhanced coagulation for disinfection byproduct mitigation. Water Res. 2009;43:1597-610 pubmed publisher
    ..Outstanding issues need to be addressed before TiO(2) photocatalysis is considered feasible for DBP mitigation; traditional strategies, including enhanced coagulation, may be more appropriate...
  72. Zhang X, Bull R, Fisher J, Cotruvo J, Cummings B. The synergistic effect of sodium chlorite and bromochloroacetic acid on BrO3(-)-induced renal cell death. Toxicology. 2011;289:151-9 pubmed publisher
    ..These data support the novel finding that mixtures of DBPs increase BrO(3)(-)-induced renal cell death by DNA-dependent and -independent mechanisms, and could alter how the risk of these DBPs towards humans is assessed...
  73. Kosaka K, Asami M, Takei K, Akiba M. Analysis of bromate in drinking water using liquid chromatography-tandem mass spectrometry without sample pretreatment. Anal Sci. 2011;27:1091-5 pubmed
    ..2-2.3 µg/L. The results of the present study indicated that the proposed method was suitable for determining bromate concentrations in drinking water without sample pretreatment...
  74. Spassova M, Miller D, Eastmond D, Nikolova N, Vulimiri S, Caldwell J, et al. Dose-response analysis of bromate-induced DNA damage and mutagenicity is consistent with low-dose linear, nonthreshold processes. Environ Mol Mutagen. 2013;54:19-35 pubmed publisher
    ..Overall, the statistical analyses of DNA damage and mutations induced by KBrO(3) are consistent with a low-dose linear response and do not provide convincing evidence for the presence of a threshold...
  75. Borchardt S, Allain E, Michels J, Stearns G, Kelly R, McCoy W. Reaction of acylated homoserine lactone bacterial signaling molecules with oxidized halogen antimicrobials. Appl Environ Microbiol. 2001;67:3174-9 pubmed
    ..This work suggests that oxidized halogens may control biofilm not only via a cidal mechanism, but also by possibly interfering with 3-oxo acylated homoserine lactone-based cell signaling...
  76. Singh H, Muneer M, Bahnemann D. Photocatalysed degradation of a herbicide derivative, bromacil, in aqueous suspensions of titanium dioxide. Photochem Photobiol Sci. 2003;2:151-6 pubmed
    ..5-Hydroxy-3-sec-butyl-6-methyl uracil (2) and diisopropyl urea (16) were identified as the degradation products by GC-MS analysis and probable pathways for the formation of the products have been proposed...
  77. Blank M, Soo L. Electromagnetic acceleration of the Belousov-Zhabotinski reaction. Bioelectrochemistry. 2003;61:93-7 pubmed
    ..A mechanism based on interaction with moving electrons offers a way of explaining the ability of EM fields to stimulate gene expression, in particular the stress response, since electrons have been shown to move in DNA...
  78. Hu X, Li H, Liang W. Reaction mechanism of uracil bromination by HBrO: a new way to generate the enol-keto form of 5-bromouracil. J Phys Chem A. 2006;110:11188-93 pubmed
    ..A proton-transfer process from C5 to O10 is facilitated by explicit H(2)O, which results in enol-keto form intermediate of this modified base (defined as BrU*). These results indicate a new way to generate the enol-keto form of BrU...
  79. Bahr C, Schumacher J, Ernst M, Luck F, Heinzmann B, Jekel M. SUVA as control parameter for the effective ozonation of organic pollutants in secondary effluent. Water Sci Technol. 2007;55:267-74 pubmed
    ..The results can be used as a guideline for the control of the oxidation performance at large scale ozonation units...
  80. Bao L, Yao X, Tsi D, Yau C, Chia C, Nagai H, et al. Protective effects of bilberry (Vaccinium myrtillus L.) extract on KBrO3-induced kidney damage in mice. J Agric Food Chem. 2008;56:420-5 pubmed
    ..These findings demonstrate that the protective effect of bilberry extract is attributed to its free radical scavenging activity and lipid peroxidation inhibitory effect...
  81. Fukushi K, Yamazaki R, Yamane T. Determination of bromate in highly saline samples using CZE with on-line transient ITP. J Sep Sci. 2009;32:457-61 pubmed publisher
    ..The recovery of bromate in seawater samples was 85-105%. Linear regression equations relating area and height responses to concentration for bromate were obtained using the salt samples...
  82. Amouroux R, Campalans A, Epe B, Radicella J. Oxidative stress triggers the preferential assembly of base excision repair complexes on open chromatin regions. Nucleic Acids Res. 2010;38:2878-90 pubmed publisher
  83. Carr A, van den Berg J, Winterbourn C. Differential reactivities of hypochlorous and hypobromous acids with purified Escherichia coli phospholipid: formation of haloamines and halohydrins. Biochim Biophys Acta. 1998;1392:254-64 pubmed
    ..Bromohydrins (formed directly or through the action of bromamines) may, therefore, be suitable biomarkers for the production of HOBr in vivo...
  84. Wagner H, Pepich B, Hautman D, Munch D. Performance evaluation of a method for the determination of bromate in drinking water by ion chromatography (EPA method 317.0) and validation of EPA method 324.0. J Chromatogr A. 2000;884:201-10 pubmed
    ..This manuscript describes the performance evaluation work with Method 317.0 and efforts completed at EPA's Technical Support Center that improved the sensitivity of Method 317.0, leading to the development of EPA Method 324.0..
  85. Carr A, Decker E, Park Y, Frei B. Comparison of low-density lipoprotein modification by myeloperoxidase-derived hypochlorous and hypobromous acids. Free Radic Biol Med. 2001;31:62-72 pubmed
    ..Our data show that even though HOBr has different reactivities than HOCl with apoB, it is able to alter the charge of LDL, converting it into a potentially atherogenic particle...
  86. Noguchi H, Nakajima A, Watanabe T, Hashimoto K. Removal of bromate ion from water using TiO2 and alumina-loaded TiO2 photocatalysts. Water Sci Technol. 2002;46:27-31 pubmed
    ..It was concluded from these results that the photocatalytic reduction of bromate ion can be promoted by pH control of water or by controlling the surface charge of the photocatalyst by loading alumina without pH control of water...
  87. Umemura T, Kanki K, Kuroiwa Y, Ishii Y, Okano K, Nohmi T, et al. In vivo mutagenicity and initiation following oxidative DNA lesion in the kidneys of rats given potassium bromate. Cancer Sci. 2006;97:829-35 pubmed
    ..The two-step experiment shows that cells exposed to the alteration of the intranuclear status by oxidative stress including 8-OHdG formation might be able to form tumors with appropriate promotion...
  88. Takayanagi T, Ishida M, Mbuna J, Driouich R, Motomizu S. Determination of bromate ion in drinking water by capillary zone electrophoresis with direct photometric detection. J Chromatogr A. 2006;1128:298-302 pubmed
    ..Bromate ion added in a tap water at the concentration of 8 x 10(-8)M was quantitatively recovered by diluting it 1/10...
  89. Smart D, Chipman J, Hodges N. Activity of OGG1 variants in the repair of pro-oxidant-induced 8-oxo-2'-deoxyguanosine. DNA Repair (Amst). 2006;5:1337-45 pubmed
    ..This finding suggests the homozygous cys326/cys326 genotype may be classified as a biomarker of disease susceptibility, which is in support of a growing body of epidemiological evidence...
  90. Liu J, Yang T, Zhu G, Chen H, Li P, Lin X, et al. Determination of trace formaldehyde by solid substrate-room temperature phosphorescence quenching method based on the rose bengal-potassium bromate-Tween-80 system. Spectrochim Acta A Mol Biomol Spectrosc. 2008;69:1004-9 pubmed
    ..The mechanism of determination of trace formaldehyde by SS-RTP quenching method based on the rose bengal-KBrO(3)-Tween-80 system is also discussed...
  91. Yu F, Song P, Li P, Wang B, Han K. Development of reversible fluorescence probes based on redox oxoammonium cation for hypobromous acid detection in living cells. Chem Commun (Camb). 2012;48:7735-7 pubmed publisher
    ..The two probes contain a hydroxylamine functional group for the monitoring of HOBr oxidation/ascorbic acid reduction events. Confocal fluorescence microscopy has established the HOBr detection in live-cells...
  92. McDorman K, Pachkowski B, Nakamura J, Wolf D, Swenberg J. Oxidative DNA damage from potassium bromate exposure in Long-Evans rats is not enhanced by a mixture of drinking water disinfection by-products. Chem Biol Interact. 2005;152:107-17 pubmed
    ..These data are consistent with previous studies where chronic exposure to this chemical mixture in drinking water resulted in a less than additive carcinogenic response in Tsc2 mutant Long-Evans rats...