magnesium chloride


Summary: Magnesium chloride. An inorganic compound consisting of one magnesium and two chloride ions. The compound is used in medicine as a source of magnesium ions, which are essential for many cellular activities. It has also been used as a cathartic and in alloys.

Top Publications

  1. Duan S, Mathews D, Turner D. Interpreting oligonucleotide microarray data to determine RNA secondary structure: application to the 3' end of Bombyx mori R2 RNA. Biochemistry. 2006;45:9819-32 pubmed
    ..It should also facilitate the design of antisense and siRNA oligonucleotides...
  2. Spasov A, Iezhitsa I, Kharitonova M, Kravchenko M. Effect of magnesium chloride and magnesium L-aspartate on seizure threshold in rats under conditions of dietary magnesium deficiency. Bull Exp Biol Med. 2007;144:214-6 pubmed
    ..Seizure threshold and latencies of the first jerk and first episode of clonic seizures increased over 3 weeks after peroral administration of Mg2+ salts. The combination of Mg2+ salts and pyridoxine was most effective in this respect...
  3. Bautista Gallego J, Arroyo López F, Duran Quintana M, Garrido Fernandez A. Individual effects of sodium, potassium, calcium, and magnesium chloride salts on Lactobacillus pentosus and Saccharomyces cerevisiae growth. J Food Prot. 2008;71:1412-21 pubmed
    ..Microbial susceptibility and resistance were found to be nonlinearly dose related...
  4. Morgan T, Power G, Venkatesh B, Jones M. Acid-base effects of a bicarbonate-balanced priming fluid during cardiopulmonary bypass: comparison with Plasma-Lyte 148. A randomised single-blinded study. Anaesth Intensive Care. 2008;36:822-9 pubmed
    ..These are likely to be gluconate and/or acetate. Whether surges of exogenous anions during bypass can be harmful requires further study...
  5. Karimi M, Mohammadi F, Behmanesh F, Samani S, Borzouee M, Amoozgar H, et al. Effect of combination therapy of hydroxyurea with l-carnitine and magnesium chloride on hematologic parameters and cardiac function of patients with beta-thalassemia intermedia. Eur J Haematol. 2010;84:52-8 pubmed publisher
    ..We assessed the effect of combination therapy of hydroxyurea with l-carnitine and magnesium chloride on hematologic parameters and cardiac function of patients with beta-thalassemia intermedia.
  6. Fu Z, Yang F, Hsu H, Lu Y. Drinking deep seawater decreases serum total and low-density lipoprotein-cholesterol in hypercholesterolemic subjects. J Med Food. 2012;15:535-41 pubmed publisher
    ..In conclusion, DSW was apparently effective in reducing blood total cholesterol and LDL-C, and also in decreasing lipid peroxidation in hypercholesterolemic subjects...
  7. Muradov J, Hagg T. Intravenous infusion of magnesium chloride improves epicenter blood flow during the acute stage of contusive spinal cord injury in rats. J Neurotrauma. 2013;30:840-52 pubmed publisher
    ..Moreover, intravenous infusion of magnesium chloride, used clinically to treat CNS vasospasm, greatly improved the number of perfused microvessels at 24 and 48?h...
  8. Kishimoto Y, Tani M, Uto Kondo H, Saita E, Iizuka M, Sone H, et al. Effects of magnesium on postprandial serum lipid responses in healthy human subjects. Br J Nutr. 2010;103:469-72 pubmed publisher
    ..05) were significantly lower at 2 h after the fat-with-Mg meal compared with the fat-only meal. The present study indicated that Mg supplementation could inhibit fat absorption and improve postprandial hyperlipidaemia in healthy subjects...
  9. Liu Y, Chen H, Kenney L, Yan J. A divalent switch drives H-NS/DNA-binding conformations between stiffening and bridging modes. Genes Dev. 2010;24:339-44 pubmed publisher
    ..The stiffening form is present under physiological conditions, and directly responds to pH and temperature in vitro. Our findings have broad implications and require a reinterpretation of the mechanism by which H-NS regulates genes...

More Information

Publications104 found, 100 shown here

  1. Chen H, Meisburger S, Pabit S, Sutton J, Webb W, Pollack L. Ionic strength-dependent persistence lengths of single-stranded RNA and DNA. Proc Natl Acad Sci U S A. 2012;109:799-804 pubmed publisher
    ..Our results illustrate the complex interplay between conformation and ion environment that modulates nucleic acid function in vivo...
  2. Spivey W, Skobeloff E, Levin R. Effect of magnesium chloride on rabbit bronchial smooth muscle. Ann Emerg Med. 1990;19:1107-12 pubmed
    ..The objective of this study was to determine the extent to which magnesium relaxes bronchial smooth muscle during induced contraction...
  3. Pan T, Sosnick T. Intermediates and kinetic traps in the folding of a large ribozyme revealed by circular dichroism and UV absorbance spectroscopies and catalytic activity. Nat Struct Biol. 1997;4:931-8 pubmed
    ..Taken together with previous submillisecond relaxation kinetics of tRNA tertiary structure, we suggest that error-free RNA folding can be on the order of milliseconds...
  4. Cheng J, Lai Y, Chen C, Cheng C, Chiou L. Magnesium chloride and ruthenium red attenuate the antiallodynic effect of intrathecal gabapentin in a rat model of postoperative pain. Anesthesiology. 2003;98:1472-9 pubmed
    ..b>Magnesium chloride, ruthenium red, and spermine have been shown to modulate [3H]gabapentin binding to this binding site in ..
  5. Geertman H, van der Starre P, Sie H, Beukema W, van Rooyen Butijn M. Magnesium in addition to sotalol does not influence the incidence of postoperative atrial tachyarrhythmias after coronary artery bypass surgery. J Cardiothorac Vasc Anesth. 2004;18:309-12 pubmed
    ..Several etiologic factors are mentioned. Prophylactic intervention with sotalol is reported to reduce the incidence of POAT. The authors studied the effect of magnesium chloride (MgCl2) in addition to sotalol in the prevention of POAT.
  6. Luo Y, Cho H, Jones R, Jin C, McKeehan W. Improved production of recombinant fibroblast growth factor 7 (FGF7/KGF) from bacteria in high magnesium chloride. Protein Expr Purif. 2004;33:326-31 pubmed
    ..product was improved to about 17 mg per liter per OD(600) in strain BL21(DE3)pLysS by inclusion of 10-100mM magnesium chloride (MgCl(2)) in the culture medium...
  7. Mikulecky P, Takach J, Feig A. Entropy-driven folding of an RNA helical junction: an isothermal titration calorimetric analysis of the hammerhead ribozyme. Biochemistry. 2004;43:5870-81 pubmed
    ..Our approach addresses several significant challenges that accompany the study of junction folding, and should prove useful in defining the thermodynamic determinants of stability in these important RNA motifs...
  8. Feng D, Zhang B, Lu W, Yang S. Protein expression analysis of Halobacillus dabanensis D-8T subjected to salt shock. J Microbiol. 2006;44:369-74 pubmed
    ..Eight of the up-regulated proteins were identified using MALDI-TOF/MS and MASCOT, and were similar to proteins involved in signal transduction, proteins participating in energy metabolism pathways and proteins involved in stress...
  9. Dai B, Kang S, Huynh T, Lei H, Castelli M, Hu J, et al. Salts drive controllable multilayered upright assembly of amyloid-like peptides at mica/water interface. Proc Natl Acad Sci U S A. 2013;110:8543-8 pubmed publisher
    ..Further studies show that the growth of multilayered, all-upright nanostructures is a common phenomenon for GAV-9 at the mica/water interface, under a variety of salt types and a wide range of salt concentrations. ..
  10. Wu Y, Briley Saebo K, Xie J, Zhang R, Wang Z, He C, et al. Inflammatory bowel disease: MR- and SPECT/CT-based macrophage imaging for monitoring and evaluating disease activity in experimental mouse model--pilot study. Radiology. 2014;271:400-7 pubmed publisher
    ..SPIO nanoparticles and (111)In-labeled macrophages could be observed in vivo at MR imaging and SPECT/CT in mice with IBD. Percentage NE at MR imaging correlates with disease activity. ..
  11. Nakamura M, Yokoyama S, Kayamori Y, Iso H, Kitamura A, Okamura T, et al. HDL cholesterol performance using an ultracentrifugation reference measurement procedure and the designated comparison method. Clin Chim Acta. 2015;439:185-90 pubmed publisher
  12. Myers T, Sherbow T, Fettinger J, Berben L. Synthesis and characterization of bis(imino)pyridine complexes of divalent Mg and Zn. Dalton Trans. 2016;45:5989-98 pubmed publisher
    ..Cyclic voltammetry measurements reveal that in complexes, 1, 4, 5, 6, the I2P0, I2P−, and I2P2− ligand charge states are accessible electrochemically. ..
  13. Yehia H, Hassanein W, Ibraheim S. Purification and characterisation of the extracellular cholesterol oxidase enzyme from Enterococcus hirae. BMC Microbiol. 2015;15:178 pubmed publisher
    ..The highest specific enzyme activity and highest purification fold of purified enzyme were achieved after using Sephadex G-100. ..
  14. Yalcintas E, Gaona X, Altmaier M, Dardenne K, Polly R, Geckeis H. Thermodynamic description of Tc(iv) solubility and hydrolysis in dilute to concentrated NaCl, MgCl2 and CaCl2 solutions. Dalton Trans. 2016;45:8916-36 pubmed publisher
    ..Based on the newly generated experimental data and previous spectroscopic observations, new comprehensive chemical, thermodynamic and activity models (SIT, Pitzer) for these systems are derived. ..
  15. Guha T, Hausner G. Insertion of Group II Intron-Based Ribozyme Switches into Homing Endonuclease Genes. Methods Mol Biol. 2017;1498:135-152 pubmed
    ..That addition of exogenous magnesium chloride (MgCl2) appears to stimulate splicing of nonnative group II introns in Escherichia coli and the ..
  16. Elshafei A, Ali N, Mohamed L. Cytidine deaminase activity in Penicillium politans NRC-510. J Basic Microbiol. 2005;45:335-43 pubmed
    ..Dialysis of the cell-free extracts resulted to an increase in enzyme activity by about 30%. To our knowledge the thermophilic nature of the cytidine deaminase of P. politans NRC-510 is unique. ..
  17. Kuznetsov S, Ren C, Woodson S, Ansari A. Loop dependence of the stability and dynamics of nucleic acid hairpins. Nucleic Acids Res. 2008;36:1098-112 pubmed
    ..The results also reinforce the idea that folding times are dominated by an entropic search for the correct nucleating conformation. ..
  18. Liang C, Xiao W, Hao H, Xiaoqing L, Chao L, Lei Z, et al. Effects of Mg(2+)on spectral characteristics and photosynthetic functions of spinach photosystem II. Spectrochim Acta A Mol Biomol Spectrosc. 2009;72:343-7 pubmed publisher
    ..The photochemical activity and oxygen evolving rate of PSII were also enhanced by Mg(2+). This is viewed as evidence that Mg(2+) can promote energy transfer and oxygen evolution in PSII of spinach. ..
  19. Zhou N, Peng R, Schönning M, Pettersson R. SCC of 2304 Duplex Stainless Steel-Microstructure, Residual Stress and Surface Grinding Effects. Materials (Basel). 2017;10: pubmed publisher
    ..SCC tests were conducted in boiling magnesium chloride according to ASTM G36; specimens were exposed both without external loading and with varied levels of four-..
  20. Sio S, Suehiro T, Sugiura R, Takeuchi M, Mukai H, Kuno T. The role of the regulatory subunit of fission yeast calcineurin for in vivo activity and its relevance to FK506 sensitivity. J Biol Chem. 2005;280:12231-8 pubmed
    ..These results suggest that Cnb1 is essential for the activation of calcineurin and that the activated calcineurin is the pharmacological target of the FKBP12-FK506 complex in vivo. ..
  21. Amato J, Chung J, Cvetovich R, Gong X, McLaughlin M, Reamer R. Synthesis of 1-tert-butyl-4-chloropiperidine: generation of an N-tert-butyl group by the reaction of a dimethyliminium salt with methylmagnesium chloride. J Org Chem. 2005;70:1930-3 pubmed
  22. Siddiqi N. Protective effect of magnesium chloride on sodium fluoride induced alterations in various hydroxyproline fractions in rat lungs. Cell Mol Biol (Noisy-le-grand). 2011;57:87-92 pubmed
    ..The present study was carried out to study the reported protective effect of magnesium chloride on sodium fluoride (NaF) induced alterations in rat lung hydroxyproline/ collagen content...
  23. Shanker A, Yamada K, Green K, Yamada K, Saffitz J. Matrix-protein-specific regulation of Cx43 expression in cardiac myocytes subjected to mechanical load. Circ Res. 2005;96:558-66 pubmed
    ..Changes in the composition of the extracellular matrix may affect electrical coupling in cardiac myocytes. ..
  24. Siddiqi N. Effect of sodium fluoride and magnesium chloride on different hydroxyproline fractions in rat liver. Indian J Biochem Biophys. 2012;49:130-3 pubmed
    ..05) in total collagen content. Thus, the present study demonstrated that NaF had no significant effect on total Hyp and collagen, indicating that its use in various products may not interfere with the liver collagen. ..
  25. Monti D, Bazzan A, Zabrecky G, Newberg A. Brief Report: Stability and Chemical Characteristics of Injectable Ascorbic Acid for Patients With Cancer. Altern Ther Health Med. 2017;: pubmed
    ..The IVAA was prepared in sterile water, together with magnesium chloride (MgCl) and calcium gluconate (CaGluc) as buffers...
  26. Lee M, Chang Y, Hong E, Grubb J, Chang C, Bishop D, et al. Calcium ion promotes yeast Dmc1 activity via formation of long and fine helical filaments with single-stranded DNA. J Biol Chem. 2005;280:40980-4 pubmed
    ..Our data support the view that the active form of Dmc1 protein is a helical filament rather than a ring. We speculate that Ca(2+) plays a significant role in regulating meiotic recombination. ..
  27. Huang L, Tang D, Yappert M, Borchman D. Oxidation-induced changes in human lens epithelial cells 2. Mitochondria and the generation of reactive oxygen species. Free Radic Biol Med. 2006;41:926-36 pubmed
    ..With extended hyperoxic insult, the oxidants overwhelm the antioxidant defense system and eventually cell death ensues. ..
  28. Desai R, Kilburn D, Lee H, Woodson S. Increased ribozyme activity in crowded solutions. J Biol Chem. 2014;289:2972-7 pubmed publisher
    ..We conclude that molecular crowders stabilize the native ribozyme and favor the active structure relative to compact inactive folding intermediates. ..
  29. McGarry K, Walker S, Wang H, Fredrick K. Destabilization of the P site codon-anticodon helix results from movement of tRNA into the P/E hybrid state within the ribosome. Mol Cell. 2005;20:613-22 pubmed
    ..The effects of G2252U are suppressed by C2394A, further implicating the P/E state in mRNA destabilization. This work uncovers a functional attribute of the P/E state crucial for understanding translation. ..
  30. Joly N, Rappas M, Buck M, Zhang X. Trapping of a transcription complex using a new nucleotide analogue: AMP aluminium fluoride. J Mol Biol. 2008;375:1206-11 pubmed
  31. Eoff R, Sanchez Ponce R, Guengerich F. Conformational changes during nucleotide selection by Sulfolobus solfataricus DNA polymerase Dpo4. J Biol Chem. 2009;284:21090-9 pubmed publisher
    ..We now present a model for nucleotide selection by Dpo4 that arises from a synthesis of both structural and kinetic data. ..
  32. Mijares D, Kulkarni A, Lewis K, Yao F, Xi Q, Tannous S, et al. Oral bone loss induced by mineral deficiency in a rat model: effect of a synthetic bone mineral (SBM) preparation. Arch Oral Biol. 2012;57:1264-73 pubmed publisher
    ..SBM, administered orally, may have the potential as an osteoporosis therapeutic agent in minimizing or preventing alveolar bone loss induced by mineral deficiency. ..
  33. Hoane M. Magnesium therapy and recovery of function in experimental models of brain injury and neurodegenerative disease. Clin Calcium. 2004;14:65-70 pubmed
    ..Specifically a summary of the ability of magnesium chloride (MgCl(2)) to induce recovery of chronic behavioral impairments and the establishment of MgCl(2)'s wide ..
  34. Riggs B, Lansley T, Ryals P. Phosphatidylinositol synthase of Tetrahymena: inositol isomers as substrates in phosphatidylinositol biosynthesis and headgroup exchange reactions. J Eukaryot Microbiol. 2007;54:119-24 pubmed
    ..The data suggest two routes for the formation of phosphatidyl-non-myo-inositols in Tetrahymena and the potential for the production of novel, non-myo-inositol-containing second messengers. ..
  35. Gałuszka A, Migaszewski Z, Podlaski R, Dołęgowska S, Michalik A. The influence of chloride deicers on mineral nutrition and the health status of roadside trees in the city of Kielce, Poland. Environ Monit Assess. 2011;176:451-64 pubmed publisher
    ..The pH of alkaline soils favored greater bioavailability of B and reduced bioavailability of Na and Zn by the trees examined. ..
  36. Khan A, Mishra S, Germann M. Cyclic enzymatic solid phase synthesis of isotopically labeled DNA oligonucleotides. Nucleosides Nucleotides Nucleic Acids. 2009;28:1030-41 pubmed publisher
    ..The developed protocol was used to generate a selectively [(13)C, (15)N] G labeled 10-mer duplex. ..
  37. Michelin M, Peixoto Nogueira S, Silva T, Jorge J, Terenzi H, Teixeira J, et al. A novel xylan degrading ?-D-xylosidase: purification and biochemical characterization. World J Microbiol Biotechnol. 2012;28:3179-86 pubmed publisher
    ..TLC confirmed the capacity of the enzyme in hydrolyzing xylan and larger xylo-oligosaccharides, as xylopentaose. ..
  38. Laudadio E, Minnelli C, Amici A, Massaccesi L, Mobbili G, Galeazzi R. Liposomal Formulations for an Efficient Encapsulation of Epigallocatechin-3-gallate: An in- Silico/Experimental Approach. Molecules. 2018;23: pubmed publisher
    ..Thus, the combination of this anionic liposomal formulation with magnesium chloride, avoids time-consuming separation steps of unentrapped active principle and appears particularly suitable ..
  39. Collopy Junior I, Kneipp L, da Silva F, Rodrigues M, Alviano C, Meyer Fernandes J. Characterization of an ecto-ATPase activity in Fonsecaea pedrosoi. Arch Microbiol. 2006;185:355-62 pubmed
    ..Based on the differential expression of ecto-ATPases in the different morphological stages of F. pedrosoi, the putative role of this enzyme in fungal biology is discussed. ..
  40. Ma J, Zhao Y, Niu D, Chai X. [Experimental study on stabilization of sewage sludge by MOC]. Huan Jing Ke Xue. 2009;30:845-50 pubmed
    ..Leaching experiments of sludge show that heavy metal concentrations of Cu, Zn, Cd, Cr, As in lixivium from sludge are lower than leachability standard. ..
  41. Han S, Crowther C, Moore V. Magnesium maintenance therapy for preventing preterm birth after threatened preterm labour. Cochrane Database Syst Rev. 2013;:CD000940 pubmed publisher
  42. Enomoto T, Osugi T, Satoh H, McIntosh T, Nabeshima T. Pre-Injury magnesium treatment prevents traumatic brain injury-induced hippocampal ERK activation, neuronal loss, and cognitive dysfunction in the radial-arm maze test. J Neurotrauma. 2005;22:783-92 pubmed
    ..05) in the radial-arm maze test. The present study demonstrates that pretreatment with Mg(2+) prevents post-traumatic hippocampal ERK activation and neuronal loss, and cognitive dysfunction in the radial-arm maze test. ..
  43. Qiu X, Mou Y, Zhao M, Zhang W, Han D, Ren M, et al. Halobellus inordinatus sp. nov., from a marine solar saltern and an inland salt lake of China. Int J Syst Evol Microbiol. 2013;63:3975-80 pubmed publisher
    ..nov. is proposed. The type strain is YC20(T) (?=?CGMCC 1.12120(T)?=?JCM 18361(T)) and the other strain is XD15 (?=?CGMCC 1.12236?=?JCM 18648). ..
  44. Haider S, Sadir S, Naqvi F, Batool Z, Tabassum S, Khaliq S, et al. Magnesium treatment palliates noise-induced behavioral deficits by normalizing DAergic and 5-HTergic metabolism in adult male rats. Metab Brain Dis. 2016;31:815-25 pubmed publisher
    ..b>Magnesium Chloride (MgCl2, 100 mg/kg) was administered intraperitoneally once daily for 15 days prior exposure to noise ..
  45. Tanase J, Yokoo T, Matsumura Y, Kinoshita M, Kikuchi Y, Suemori H, et al. Magnesium chloride and polyamine can differentiate mouse embryonic stem cells into trophectoderm or endoderm. Biochem Biophys Res Commun. 2017;482:764-770 pubmed publisher
    b>Magnesium chloride and polyamines stabilize DNA and chromatin. Furthermore, they can induce nucleosome aggregation and chromatin condensation in vitro...
  46. Shogren Knaak M, Ishii H, Sun J, Pazin M, Davie J, Peterson C. Histone H4-K16 acetylation controls chromatin structure and protein interactions. Science. 2006;311:844-7 pubmed
  47. Callahan K, Casillas Ituarte N, Roeselova M, Allen H, Tobias D. Solvation of magnesium dication: molecular dynamics simulation and vibrational spectroscopic study of magnesium chloride in aqueous solutions. J Phys Chem A. 2010;114:5141-8 pubmed publisher
    ..experimental evidence suggest that contact ion pairing may not exist at ambient conditions in solutions of magnesium chloride up to saturation concentrations. This is not typical of most ions...
  48. Carter J, Hyland C, Steele R, Collins E. Dynamics of Mouth Opening in Hydra. Biophys J. 2016;110:1191-201 pubmed publisher
  49. Maruthiah T, Somanath B, Jasmin J, Immanuel G, Palavesam A. Production, purification and characterization of halophilic organic solvent tolerant protease from marine crustacean shell wastes and its efficacy on deproteinization. 3 Biotech. 2016;6:157 pubmed publisher
    ..This enzyme also showed maximum activity at 20 % NaCl concentration. Further, manganese chloride, magnesium chloride, calcium chloride and barium chloride influenced this enzyme activity remarkably and it was also found to be ..
  50. Roche J, Petch S, Kay J. Manipulating the dietary cation-anion difference via drenching to early-lactation dairy cows grazing pasture. J Dairy Sci. 2005;88:264-76 pubmed
    ..Milk production results suggest that DCAD for optimal production on pasture diets may be higher than the +20 mEq/100 g of DM previously identified for total mixed rations...
  51. Leiderman P, Gepshtein R, Uritski A, Genosar L, Huppert D. Effect of electrolytes on the excited-state proton transfer and geminate recombination. J Phys Chem A. 2006;110:5573-84 pubmed
    ..The model is consistent with an inhomogeneous water environment next to the excited HPTS molecule in such concentrated solutions...
  52. Hirano K, Nagata H, Ishido T, Tanaka Y, Baba Y, Ishikawa M. Sizing of single globular DNA molecules by using a circular acceleration technique with laser trapping. Anal Chem. 2008;80:5197-202 pubmed publisher
    ..We also investigated a possibility of reusing the globular DNA molecules condensed by PEG and Mg(2+) for PCR and found that PCR efficiency was not deteriorated in the presence of the condensation agents...
  53. Song M, Zhang Y, Li T, Wang Z, Yin J, Wang H. Highly sensitive detection of human thrombin in serum by affinity capillary electrophoresis/laser-induced fluorescence polarization using aptamers as probes. J Chromatogr A. 2009;1216:873-8 pubmed publisher
    ..Without the use of typical cations, a highly sensitive assay of human thrombin was developed with the corresponding detection limits of 4.38x10(-19) and 2.94x10(-19)mol in mass for standard solution and human serum, respectively...
  54. Arroyo López F, Bautista Gallego J, Chiesa A, Duran Quintana M, Garrido Fernandez A. Use of a D-optimal mixture design to estimate the effects of diverse chloride salts on the growth parameters of Lactobacillus pentosus. Food Microbiol. 2009;26:396-403 pubmed publisher
    ..The equations that expressed the growth parameters as a function of the diverse chloride salts, within the limits assayed, were developed and the corresponding z- and harmonic Z-values were estimated...
  55. Fels J, Orlov S, Grygorczyk R. The hydrogel nature of mammalian cytoplasm contributes to osmosensing and extracellular pH sensing. Biophys J. 2009;96:4276-85 pubmed publisher
    ..Its high water-absorbing capacity may allow rapid modulation of local fluidity, macromolecular crowding, and activity of intracellular environment...
  56. Guerrero Romero F, Rodriguez Moran M. Magnesium improves the beta-cell function to compensate variation of insulin sensitivity: double-blind, randomized clinical trial. Eur J Clin Invest. 2011;41:405-10 pubmed publisher insulin secretion is uncertain, our objective was to determine whether oral supplementation with magnesium chloride (MgCl(2)) improves the ability of beta-cells to compensate for variations in insulin sensitivity in non-..
  57. Carneiro R, Pacheco A, de Oliveira E Azevedo S. Growth and saxitoxin production by Cylindrospermopsis raciborskii (cyanobacteria) correlate with water hardness. Mar Drugs. 2013;11:2949-63 pubmed publisher
  58. Matsuzaki W, Takahashi H, Nakamura H, Murayama T. Effects of Glycerophospholipids on Ceramide Kinase Activity: Cardiolipin-Affected Cellular Formation of Ceramide-1-phosphate. Biol Pharm Bull. 2016;39:1708-1717 pubmed
    ..Our results revealed that cardiolipin bound to CerK and regulated the formation of C1P in vitro and in cells...
  59. Xia L, Yuwen L, Jie L, Huilin L, Xi Y, Cunxin W, et al. Kinetic studies on Na+/K+-ATPase and inhibition of Na+/K+-ATPase by ATP. J Enzyme Inhib Med Chem. 2004;19:333-8 pubmed
    ..Results showed that the MgATP complex was the real substrate with a Km value of about 0.5mM and free ATP was a competitive inhibitor with a Ki value of 0.253 mM...
  60. Tokunaga M, Arakawa T, Ishibashi M, Tokunaga H. [Familiar extremophiles, halophiles, and halophilic enzymes]. Seikagaku. 2005;77:320-31 pubmed
  61. Taheri S, Sood R. Spin-lock MRI with amplitude- and phase-modulated adiabatic waveforms: an MR simulation study. Magn Reson Imaging. 2006;24:51-9 pubmed
    ..g., hyperbolic secant, B1 independent rotation-4 (BIR-4) waveforms] can be used to distinguish materials that differ in T1/T2 ratio...
  62. Anguenot R, Nguyen Quoc B, Yelle S, Michaud D. Protein phosphorylation and membrane association of sucrose synthase in developing tomato fruit. Plant Physiol Biochem. 2006;44:294-300 pubmed
    ..Together, our results suggest that a mechanism involving protein phosphorylation/dephosphorylation and/or calcium would in part control the association of SS isoforms with membranes in developing tomato fruit...
  63. McCarron P, Donnelly R, Marouf W. Celecoxib-loaded poly(D,L-lactide-co-glycolide) nanoparticles prepared using a novel and controllable combination of diffusion and emulsification steps as part of the salting-out procedure. J Microencapsul. 2006;23:480-98 pubmed
  64. Khan O, McPhee L, Moddemann L, Del Bigio M. Calcium antagonism in neonatal rats with kaolin-induced hydrocephalus. J Child Neurol. 2007;22:1161-6 pubmed
    ..8 to 30 mg/kg were not associated with behavioral, structural, or biochemical improvements. Magnesium chloride was administered via daily subcutaneous minipump infusion (0.87 or 1...
  65. Vander Meulen K, Butcher S. Characterization of the kinetic and thermodynamic landscape of RNA folding using a novel application of isothermal titration calorimetry. Nucleic Acids Res. 2012;40:2140-51 pubmed publisher
  66. Harper N, Getty K. Effect of salt reduction on growth of Listeria monocytogenes in meat and poultry systems. J Food Sci. 2012;77:M669-74 pubmed publisher
    ..monocytogenes populations compared with beef products. These studies demonstrate that sodium may not affect the safety of preblends and emulsified meat and poultry products...
  67. Kraft J, Treder K, Peterson M, Miller W. Cation-dependent folding of 3' cap-independent translation elements facilitates interaction of a 17-nucleotide conserved sequence with eIF4G. Nucleic Acids Res. 2013;41:3398-413 pubmed publisher
    ..The data support the model in which the eIF4F complex binds directly to the BTE which base pairs simultaneously to the 5'-UTR, allowing eIF4F to recruit the 40S ribosomal subunit to the 5'-end...
  68. Amoozegar M, Makhdoumi Kakhki A, Mehrshad M, Fazeli S, Ventosa A. Halopenitus malekzadehii sp. nov., an extremely halophilic archaeon isolated from a salt lake. Int J Syst Evol Microbiol. 2013;63:3232-6 pubmed publisher
    ..nov. is proposed. The type strain is CC65(T) (?=?IBRC-M 10418(T)?=KCTC 4045(T))...
  69. Deleebeeck N, De Schamphelaere K, Janssen C. A bioavailability model predicting the toxicity of nickel to rainbow trout (Oncorhynchus mykiss) and fathead minnow (Pimephales promelas) in synthetic and natural waters. Ecotoxicol Environ Saf. 2007;67:1-13 pubmed
    ..Although the developed model seems very promising, the uncertainty around the role of alkalinity and the exact mechanisms by which Ca, Mg and pH modify Ni toxicity need to be further explored...
  70. Yap T, Chen Y, Xu T, Wen D, Vasudevan S, Lescar J. A multi-step strategy to obtain crystals of the dengue virus RNA-dependent RNA polymerase that diffract to high resolution. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2007;63:78-83 pubmed
  71. Shimamura K, Ishikawa H, Tanaka T, Hirasawa I. Use of a seeder reactor to manage crystal growth in the fluidized bed reactor for phosphorus recovery. Water Environ Res. 2007;79:406-13 pubmed
    ..Relative to the chemical cost in the case of magnesium chloride, the chemical cost in the case of magnesium hydroxide is approximately 40%...
  72. Chua C, Low H, Goo K, Sim T. Characterization of Plasmodium falciparum co-chaperone p23: its intrinsic chaperone activity and interaction with Hsp90. Cell Mol Life Sci. 2010;67:1675-86 pubmed publisher
    ..Collectively, this study has provided experimental evidence for the inherent chaperone function of Pfp23 and its interaction with PfHsp90, a sequel widely required for client protein activation...
  73. Chen M, He S, Yi Q, Yang M. Effect of chloride concentration on nitrogen removal from landfill leachate in sequencing batch reactor after MAP pretreatment. Water Sci Technol. 2010;62:1574-9 pubmed publisher
    ..DGGE analysis indicated that high diversity of Ammonium oxidizing bacteria (AOB) could be maintained at a Cl? concentration of 12,000 mg/L...
  74. Sanchez H, Suzuki Y, Yokokawa M, Takeyasu K, Wyman C. Protein-DNA interactions in high speed AFM: single molecule diffusion analysis of human RAD54. Integr Biol (Camb). 2011;3:1127-34 pubmed publisher
    ..These short-range interactions were usually inaccessible by other methods based on optical resolution. RAD54 monomers displayed a diffusive behavior unrelated to the motor activity...
  75. Bristol A, Carew T. Differential role of inhibition in habituation of two independent afferent pathways to a common motor output. Learn Mem. 2005;12:52-60 pubmed
  76. Manavbasi Y, Süleymanoglu E. Nucleic acid-phospholipid recognition: Fourier transform infrared spectrometric characterization of ternary phospholipid-inorganic cation-DNA complex and its relevance to chemicopharmaceutical design of nanometric liposome based gene delivery formula. Arch Pharm Res. 2007;30:1027-40 pubmed
    ..The role of residual and surface water on these associations, as well as on chain packing is also discussed followed by possible implications of the ternary complex formation for further gene transfer designs...
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    ..These observations suggest a possible role of Mg(+2) chelation by these quinones in increasing TOPO II thiol and/or amino/imino reactivity with these orthoquinones...
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    ..The results show that the HO2 loss through heterogeneous interaction with salt surface is not sufficiently rapid to explain the observed differences between modeled and measured HO2 concentrations in remote coastal areas...
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    ..The treated silica also resulted in narrower molecular weight distribution (MWD) due to the more uniform active sites produced. There was no significant change in polymer morphology upon treatment of the silica...
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    ..After inoculation of bread dough with activated Bacillus licheniformis (ATCC 9789) and Bacillus subtilis (ATCC 6633), DNA was extracted from the dough and subjected to PCR. Then simplex and multiplex PCR tests were optimised...
  81. Hammond N, Bellomo R, Gallagher M, Gattas D, Glass P, Mackle D, et al. The Plasma-Lyte 148 v Saline (PLUS) study protocol: a multicentre, randomised controlled trial of the effect of intensive care fluid therapy on mortality. Crit Care Resusc. 2017;19:239-246 pubmed
    ..0.9% sodium chloride (saline) is the most commonly administered resuscitation fluid on a global basis but emerging evidence suggests that its high chloride content may have important adverse effects...
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    reaction: see text] The 5-bromopyridyl-2-magnesium chloride (2), which was not accessible previously, was efficiently synthesized for the first time via an iodo-magnesium exchange reaction with 5-bromo-2-iodopyridine (1)...
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    ..Fetuses on day 20 of gestation from pregnant Crj:CD(SD)IGS rats were injected with 10 w/v% magnesium chloride/10 vol% neutral buffered formalin solution into the thoracic cavity, and then fixed in 10 vol% neutral ..
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    Polyols (glycerol and sorbitol) and salts (magnesium sulfate, sodium sulfate, and magnesium chloride) have been used to study the refolding of the acid-induced state of human placental cystatin (HPC), which is a low molecular weight (12,..
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    ..heavy metals (Pb, Cd, Zn, Hg and As) were determined in 17 commercial samples of Nigari, 15 samples of crude magnesium chloride (sea water) products as a food additive and 2 magnesium-containing foods...
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    ..The alkyne functionality also provides a multitude of opportunities for further synthetic transformations. The short asymmetric synthesis of (+)-angustureine 7 and (-)-cuspareine 10 was realized with use of this approach...
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    ..Hence, the exact position of the charges should be considered in the design of any inhibitor of the interactions of TAR RNA...
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    ..It can be concluded that the newly introduced CEM method is a potent additional technique to effectively prepare modified-biochar in terms of a simple and time-saving modification method. ..
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    ..To study the enzymological characterization of a fibrinolytic enzyme (FII(a)) from Agkistrodon acutus venom...
  91. Sorci L, Cimadamore F, Scotti S, Petrelli R, Cappellacci L, Franchetti P, et al. Initial-rate kinetics of human NMN-adenylyltransferases: substrate and metal ion specificity, inhibition by products and multisubstrate analogues, and isozyme contributions to NAD+ biosynthesis. Biochemistry. 2007;46:4912-22 pubmed
    ..Distinctive differences in their substrate specificity and metal ion selectivity also permitted us to quantify individual isozyme contributions to NAD+ formation in human cell extracts...
  92. Nikolakaki E, Drosou V, Sanidas I, Peidis P, Papamarcaki T, Iakoucheva L, et al. RNA association or phosphorylation of the RS domain prevents aggregation of RS domain-containing proteins. Biochim Biophys Acta. 2008;1780:214-25 pubmed
    ..RNA binding or SRPK1-mediated phosphorylation prevents aggregation and may serve to modulate the RS domain interaction modes...