hydrochloric acid

Summary

Summary: A strong corrosive acid that is commonly used as a laboratory reagent. It is formed by dissolving hydrogen chloride in water. GASTRIC ACID is the hydrochloric acid component of GASTRIC JUICE.

Top Publications

  1. Xia J, Zhang H, Sun B, Yang R, He H, Zhan Q. Spontaneous breathing with biphasic positive airway pressure attenuates lung injury in hydrochloric acid-induced acute respiratory distress syndrome. Anesthesiology. 2014;120:1441-9 pubmed publisher
    ..The authors hypothesized that SB with BIPAP would attenuate lung injury in acute respiratory distress syndrome compared with pressure-controlled ventilation...
  2. Yu P, Li J, Zhu Z, Kong H, Jin H, Zhang J, et al. Praeruptorin D and E attenuate lipopolysaccharide/hydrochloric acid induced acute lung injury in mice. Eur J Pharmacol. 2013;710:39-48 pubmed publisher
    ..extended our study to acid-induced acute lung injury and found that these two compounds protected mice from hydrochloric acid (HCl)-induced lung injury by inhibiting PMNs influx, IL-6 release and protein exudation...
  3. Walker M, Yao L, Patterson E, Joseph M, Cepinskas G, Veldhuizen R, et al. The effect of tidal volume on systemic inflammation in Acid-induced lung injury. Respiration. 2011;81:333-42 pubmed publisher
    ..Previous studies suggest that mechanical ventilation (MV) may be a key mediator of MOF through an upregulation of the systemic inflammatory response...
  4. Tessema G, Møretrø T, Snipen L, Heir E, Holck A, Naterstad K, et al. Microarray-based transcriptome of Listeria monocytogenes adapted to sublethal concentrations of acetic acid, lactic acid, and hydrochloric acid. Can J Microbiol. 2012;58:1112-23 pubmed publisher
    ..monocytogenes L502 was analyzed after adaptation to pH 5 in the presence of acetic acid, lactic acid, or hydrochloric acid (HCl) at 25 °C, representing a condition encountered in mildly acidic ready-to-eat food kept at room ..
  5. Szmukler Moncler S, Bischof M, Nedir R, Ermrich M. Titanium hydride and hydrogen concentration in acid-etched commercially pure titanium and titanium alloy implants: a comparative analysis of five implant systems. Clin Oral Implants Res. 2010;21:944-50 pubmed publisher
  6. Cheng Z, Zhang F, He F, Zhang L, Guo C, Zhao S, et al. Osseointegration of titanium implants with a roughened surface containing hydride ion in a rabbit model. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2010;110:e5-12 pubmed publisher
    ..The objective of this study was to investigate the effect of hydride ion on bone formation and bone-bonding strength at the early stage of implantation...
  7. Malakar D, Dey A, Basu A, Ghosh A. Antiapoptotic role of S-adenosyl-l-methionine against hydrochloric acid induced cell death in Saccharomyces cerevisiae. Biochim Biophys Acta. 2008;1780:937-47 pubmed publisher
    ..The study could open a new avenue for detailed investigation on the curative potential of AdoMet against gastric ulcer...
  8. Allen G, Leclair T, Cloutier M, Thompson Figueroa J, Bates J. The response to recruitment worsens with progression of lung injury and fibrin accumulation in a mouse model of acid aspiration. Am J Physiol Lung Cell Mol Physiol. 2007;292:L1580-9 pubmed
    ..This injury manifests as progressively increasing alveolar instability, likely due to surfactant dysfunction caused by increasing levels of alveolar protein and fibrin...
  9. Tsushima K, Koizumi T, Yoshikawa S, Obata T, Kubo K. Polymyxin B immobilized column is effective for hydrochloric acid-induced lung injury in rats. Eur J Pharmacol. 2006;535:270-9 pubmed
    ..of this study was to examine whether hemoperfusion using polymyxin B (PMX) immobilized column improves hydrochloric acid (HCl)-induced lung injury...

More Information

Publications62

  1. Jones N, Slater R, Cadiou H, McNaughton P, McMahon S. Acid-induced pain and its modulation in humans. J Neurosci. 2004;24:10974-9 pubmed
    ..Together these data suggest a prominent role for ASIC channels and only a minor role for transient receptor potential vanilloid receptor-1 as mediators of cutaneous acid-induced pain...
  2. Thomas R. The effects of HCl and CaCl(2) injections on intracellular calcium and pH in voltage-clamped snail (Helix aspersa) neurons. J Gen Physiol. 2002;120:567-79 pubmed
    ..Acidosis inhibits spontaneous calcium release via the RYR, and leads to increased store content which is unloaded when pH(i) returns to normal. Spontaneous release is enhanced by the rise in [Ca(2+)](i) caused by inhibiting the PMCA...
  3. Yoshida A, Kageyama A, Fujino T, Nozawa Y, Yamada S. Loss of muscarinic and purinergic receptors in urinary bladder of rats with hydrochloric acid-induced cystitis. Urology. 2010;76:1017.e7-12 pubmed publisher
    ..of cystitis by characterizing the urodynamic parameters, pharmacologically relevant (muscarinic and purinergic) receptors, and the in vivo release of adenosine triphosphate (ATP) in the bladder of hydrochloric acid (HCl)-treated rats.
  4. Einbu A, Vårum K. Depolymerization and de-N-acetylation of chitin oligomers in hydrochloric acid. Biomacromolecules. 2007;8:309-14 pubmed
    ..Glucosamine is prepared from chitin, a process that is performed in concentrated acid, such as hydrochloric acid. This process involves two acid-catalyzed processes, that is, the hydrolysis of the glycosidic linkages (..
  5. Schreiber T, Hueter L, Gaser E, Schmidt B, Schwarzkopf K, Rek H, et al. PEEP has beneficial effects on inflammation in the injured and no deleterious effects on the noninjured lung after unilateral lung acid instillation. Intensive Care Med. 2006;32:740-9 pubmed
    ..We compared the effects of PEEP on the inflammatory response in injured and noninjured regions of the lung in an animal model of unilateral lung acid instillation...
  6. Fujiwara Y, Shindome C, Takeda M, Shiomi K. The roles of ERK and P38 MAPK signaling cascades on embryonic diapause initiation and termination of the silkworm, Bombyx mori. Insect Biochem Mol Biol. 2006;36:47-53 pubmed
    ..Phospho-ERK levels were maintained with diapause-interrupting treatment and declined with diapause-sustaining treatment. ERK phosphorylation is considered to have a role in diapause termination and in the resumption of development...
  7. Yusuf S, Nok A, Ameh D, Adelaiye A, Balogun E. Correlation of gastric mucosal damage with sialic acid profile in rats: effect of hydrochloric acid, pepsin and hypertonic saline. Cell Biochem Funct. 2005;23:339-45 pubmed
    ..It is concluded that gastric acidity alone is not inherently damaging and that resistance of gastric mucosa to destructive agents may be dependent on the integrity of the sialic acids...
  8. Svennerholm L. Quantitative estimation of sialic acids. II. A colorimetric resorcinol-hydrochloric acid method. Biochim Biophys Acta. 1957;24:604-11 pubmed
  9. Holzer P, Painsipp E, Jocic M, Heinemann A. Acid challenge delays gastric pressure adaptation, blocks gastric emptying and stimulates gastric fluid secretion in the rat. Neurogastroenterol Motil. 2003;15:45-55 pubmed
    ..In this study, we investigated whether luminal hydrochloric acid (HCl) may reproduce these motor alterations in phenobarbital-anaesthetized rats via activation of extrinsic ..
  10. Perrin D, Szmukler Moncler S, Echikou C, Pointaire P, Bernard J. Bone response to alteration of surface topography and surface composition of sandblasted and acid etched (SLA) implants. Clin Oral Implants Res. 2002;13:465-9 pubmed
  11. Bove M, Vieth M, Dombrowski F, Ny L, Ruth M, Lundell L. Acid challenge to the human esophageal mucosa: effects on epithelial architecture in health and disease. Dig Dis Sci. 2005;50:1488-96 pubmed
    ..A protective effect of luminal nitric oxide on DIS development is suggested...
  12. Gorguner M, Aslan S, Inandi T, Cakir Z. Reactive airways dysfunction syndrome in housewives due to a bleach-hydrochloric acid mixture. Inhal Toxicol. 2004;16:87-91 pubmed
    ..A mixture of sodium hypochlorite (bleach, 40%) and hydrochloric acid (18%) is commonly used as a household cleaning solution in our region...
  13. Hove L, Holme B, Øgaard B, Willumsen T, Tveit A. The protective effect of TiF4, SnF2 and NaF on erosion of enamel by hydrochloric acid in vitro measured by white light interferometry. Caries Res. 2006;40:440-3 pubmed
    ..7), NaF 5.3 (SD 0.4), and 7.0 (SD 0.3) for the control specimens. Compared to the control, TiF(4) protected the enamel surface from acid attack almost completely (88%), while SnF2 reduced the etch depth after 6 min by 50% and NaF by 25%...
  14. Lamb K, Kang Y, Gebhart G, Bielefeldt K. Gastric inflammation triggers hypersensitivity to acid in awake rats. Gastroenterology. 2003;125:1410-8 pubmed
    ..Nonhuman models have previously focused on responses to mechanical stimulation. We studied the response to acid stimulation in the normal and inflamed stomach in rats...
  15. Hove L, Young A, Tveit A. An in vitro study on the effect of TiF(4) treatment against erosion by hydrochloric acid on pellicle-covered enamel. Caries Res. 2007;41:80-4 pubmed
    ..These results suggest that treatment of enamel with a TiF(4) solution, with or without pellicle removal, may provide protection for the enamel against acid attack...
  16. Allen G, Bates J. Dynamic mechanical consequences of deep inflation in mice depend on type and degree of lung injury. J Appl Physiol (1985). 2004;96:293-300 pubmed
    ..Mice were administered 50 microl of either saline (n = 8), 0.01 M (n = 9) or 0.025 M (n = 8) hydrochloric acid, or 50 microg (n = 10) or 150 microg (n = 6) of LPS and were mechanically ventilated 24-48 h later...
  17. Einbu A, Grasdalen H, Vårum K. Kinetics of hydrolysis of chitin/chitosan oligomers in concentrated hydrochloric acid. Carbohydr Res. 2007;342:1055-62 pubmed
    The kinetics of hydrolysis in concentrated hydrochloric acid (12...
  18. Meyer Lueckel H, Paris S, Kielbassa A. Surface layer erosion of natural caries lesions with phosphoric and hydrochloric acid gels in preparation for resin infiltration. Caries Res. 2007;41:223-30 pubmed
    ..05). An effective reduction in the surface layer of natural enamel caries can be achieved by etching with 15% hydrochloric acid gel for 90-120 s.
  19. Richter T, Caicedo A, Roper S. Sour taste stimuli evoke Ca2+ and pH responses in mouse taste cells. J Physiol. 2003;547:475-83 pubmed
    ..The primary transducer protein(s) for sour taste remain undiscovered...
  20. Tsurumaru S, Kawamori A, Mitsumasu K, Niimi T, Imai K, Yamashita O, et al. Disappearance of chorion proteins from Bombyx mori eggs treated with HCl solution to prevent diapause. J Insect Physiol. 2010;56:1721-7 pubmed publisher
    ..We also discuss the role of these proteins in choriogenesis...
  21. Chapman B, Ross T. Escherichia coli and Salmonella enterica are protected against acetic acid, but not hydrochloric acid, by hypertonicity. Appl Environ Microbiol. 2009;75:3605-10 pubmed publisher
    ..and observed that the average "lag" time prior to inactivation decreases in the presence of hydrochloric acid but not in the presence of acetic acid. For E...
  22. Van de Louw A, Jean D, Frisdal E, Cerf C, d Ortho M, Baker A, et al. Neutrophil proteinases in hydrochloric acid- and endotoxin-induced acute lung injury: evaluation of interstitial protease activity by in situ zymography. Lab Invest. 2002;82:133-45 pubmed
    ..Three groups of rats were studied 6 hours after unilateral instillation of hydrochloric acid (HCl; 0.1 N), lipopolysaccharide (LPS) (4 microg), or saline...
  23. Yang X, Chen Y, Yang F, He F, Zhao S. Enhanced initial adhesion of osteoblast-like cells on an anatase-structured titania surface formed by H2O2/HCl solution and heat treatment. Dent Mater. 2009;25:473-80 pubmed publisher
    ..This study aims to investigate the effects of anatase-structured titania surface on the response of osteoblast-like cells...
  24. Kobayashi K, Fukushima H. [Suicidal poisoning due to hydrogen sulfide produced by mixing a liquid bath essence containing sulfur and a toilet bowl cleaner containing hydrochloric acid]. Chudoku Kenkyu. 2008;21:183-8 pubmed
    ..e., 1,000 ppm. This was a rare suicide case, and it revealed the hazards of mixing of liquid bath essences containing sulfur and toilet bowl cleaners containing hydrochloric acid.
  25. Mansur M, Rocha S, Magalhães F, Benedetto J. Selective extraction of zinc(II) over iron(II) from spent hydrochloric acid pickling effluents by liquid-liquid extraction. J Hazard Mater. 2008;150:669-78 pubmed
    The selective removal of zinc(II) over iron(II) by liquid-liquid extraction from spent hydrochloric acid pickling effluents produced by the zinc hot-dip galvanizing industry was studied at room temperature...
  26. Wilks J, Slonczewski J. pH of the cytoplasm and periplasm of Escherichia coli: rapid measurement by green fluorescent protein fluorimetry. J Bacteriol. 2007;189:5601-7 pubmed
    ..The cytoplasmic pH of E. coli was measured with 4-s time resolution using a method that can be applied to any strain construct, and the periplasmic pH was measured directly for the first time...
  27. Vera P, Ordorica R, Meyer Siegler K. Hydrochloric acid induced changes in macrophage migration inhibitory factor in the bladder, peripheral and central nervous system of the rat. J Urol. 2003;170:623-7 pubmed
  28. Willumsen T, Ogaard B, Hansen B, Rølla G. Effects from pretreatment of stannous fluoride versus sodium fluoride on enamel exposed to 0.1 M or 0.01 M hydrochloric acid. Acta Odontol Scand. 2004;62:278-81 pubmed
    ..As pH of stomach vomit is usually > 1.5, SnF2 may be an interesting agent for use in the treatment and prevention of dental erosions even in patients with frequent vomiting episodes...
  29. Yang G, He F, Zhao S, Wang X, Zhao S. Effect of H2O2/HCl heat treatment of implants on in vivo peri-implant bone formation. Int J Oral Maxillofac Implants. 2008;23:1020-8 pubmed
    ..To investigate the effect of H2O/HCl heat treatment on peri-implant bone formation in vivo...
  30. Murphy C, Carroll C, Jordan K. Induction of an adaptive tolerance response in the foodborne pathogen, Campylobacter jejuni. FEMS Microbiol Lett. 2003;223:89-93 pubmed
    ..These data suggest that Campylobacter spp. have the ability to induce an ATR to sublethal treatments, which increased their ability to withstand subsequent stresses...
  31. Andrushchenko V, Vogel H, Prenner E. Optimization of the hydrochloric acid concentration used for trifluoroacetate removal from synthetic peptides. J Pept Sci. 2007;13:37-43 pubmed
    ..Our results indicate that HCl concentrations between 2 and 10 mM are adequate to remove essentially all TFA impurities without any modification of the peptide secondary structure...
  32. Caldas G, do Amaral Costa I, da Silva J, da Nóbrega R, Rodrigues F, da Costa J, et al. Antiulcerogenic activity of the essential oil of Hyptis martiusii Benth. (Lamiaceae). J Ethnopharmacol. 2011;137:886-92 pubmed publisher
    ..The aim of this study was to characterize the chemical constituents and to evaluate the anti-ulcerogenic activity of the essential oil of the leaves of Hyptis martiusii (EOHM) in in vivo models of experimental ulcers in rodents...
  33. Vandebroek L, Van Hees M, Delvaux B, Spaargaren O, Thiry Y. Relevance of Radiocaesium Interception Potential (RIP) on a worldwide scale to assess soil vulnerability to 137Cs contamination. J Environ Radioact. 2012;104:87-93 pubmed publisher
    ..The RIP could be estimated from the empirical equation: RIP = (-31.701 ? log(AER) + 58.886)(2) where AER is the fraction of acid-extractable radiocaesium...
  34. Schmidt M, Sun H, Rogne P, Scriba G, Griesinger C, Kuhn L, et al. Determining the absolute configuration of (+)-mefloquine HCl, the side-effect-reducing enantiomer of the antimalaria drug Lariam. J Am Chem Soc. 2012;134:3080-3 pubmed publisher
    ..The experimental results for (-)-erythro-mefloquine HCl matched our calculated chiroptical data for the 11R,12S model. Accordingly, we conclude that the assignment of 11R,12S to (-)-erythro-mefloquine HCl is correct...
  35. Kondo T, Oshima T, Tomita T, Fukui H, Watari J, Okada H, et al. Prostaglandin E(2) mediates acid-induced heartburn in healthy volunteers. Am J Physiol Gastrointest Liver Physiol. 2013;304:G568-73 pubmed publisher
    ..80, P = 0.029). EP1 mRNA and protein expression were observed in the normal human esophageal mucosa. Esophageal PGE(2) expression is associated with mucosal acid exposure and heartburn...
  36. Hassanali A, Cuny J, Ceriotti M, Pickard C, Parrinello M. The fuzzy quantum proton in the hydrogen chloride hydrates. J Am Chem Soc. 2012;134:8557-69 pubmed publisher
    ..We believe that the rich and insightful information we obtain for these acid hydrates provides a motivation for new experimental studies...
  37. Grimsby G, Conley S, Trentman T, Castle E, Andrews P, Mihalik L, et al. A double-blind randomized controlled trial of continuous intravenous Ketorolac vs placebo for adjuvant pain control after renal surgery. Mayo Clin Proc. 2012;87:1089-97 pubmed publisher
    ..To evaluate the efficacy and safety of a novel, continuous intravenous infusion of ketorolac, a powerful nonopioid analgesic, for postoperative pain control...
  38. Croce N, Bernardini S, Di Cecca S, Caltagirone C, Angelucci F. Hydrochloric acid alters the effect of L-glutamic acid on cell viability in human neuroblastoma cell cultures. J Neurosci Methods. 2013;217:26-30 pubmed publisher
    ..l-glutamate powder is nearly insoluble in water, many manufacturers recommend reconstituting l-glutamate in hydrochloric acid (HCl) prior to successive dilutions...
  39. Wehr N, Levine R. Quantification of protein carbonylation. Methods Mol Biol. 2013;965:265-81 pubmed publisher
    ..We present protocols for the derivatization and quantification of protein carbonylation with these two methods, including a newly described dot blot with greatly increased sensitivity...
  40. Attin T, Becker K, Wiegand A, Tauböck T, Wegehaupt F. Impact of laminar flow velocity of different acids on enamel calcium loss. Clin Oral Investig. 2013;17:595-600 pubmed publisher
    ..The aim of the study was to evaluate the impact of flow velocity under laminar flow conditions of different acidic solutions on enamel erosion...
  41. Malihan L, Nisola G, Chung W. Brown algae hydrolysis in 1-n-butyl-3-methylimidazolium chloride with mineral acid catalyst system. Bioresour Technol. 2012;118:545-52 pubmed publisher
    ..Overall results show the potential of brown algae as renewable energy resources for the production of valuable chemicals and biofuels...
  42. Gualtieri A, Viani A, Sgarbi G, Lusvardi G. In vitro biodurability of the product of thermal transformation of cement-asbestos. J Hazard Mater. 2012;205-206:63-71 pubmed publisher
    ..298 days, respectively). This proves a low potential toxicity of this secondary raw material...
  43. Chen S, Liu G, Zhang R, Qin B, Luo Y. Development of the microbial electrolysis desalination and chemical-production cell for desalination as well as acid and alkali productions. Environ Sci Technol. 2012;46:2467-72 pubmed publisher
    ..68 and 12.9, respectively. With the MEDCC, the problem with large pH changes in the anode chamber was resolved, and products of the acid and alkali were obtained...
  44. Bansal D, Ambegaonkar R, Radhika P, Sharma M. ARDS following inhalation of hydrochloric acid. J Assoc Physicians India. 2011;59:115-7 pubmed
    ..We herewith present a patient who is a goldsmith by occupation and his work consists of dissolving gold in Hydrochloric acid. He had accidentally inhaled fumes of Hydrochloric acid and presented with cough and breathlessness, later ..
  45. Zheng F, Pan C, Lai Z, Xia J, Liang Z, Liu X. [Study on germination characteristic of seed of Dendranthema indicum]. Zhong Yao Cai. 2012;35:351-4 pubmed
    ..To find out the optimum condition for the germination of seed of Dendranthema indicum by studying the effects of pretreatment,phytohormone and temperature on it, and offer the basis for its standardized culture...
  46. Cheema Dhadli S, Chong C, Kamel K, Halperin M. An acute infusion of lactic acid lowers the concentration of potassium in arterial plasma by inducing a shift of potassium into cells of the liver in fed rats. Nephron Physiol. 2012;120:p7-15 pubmed publisher
    ..Potassium (K(+)) input occurs after meals or during ischemic exercise and is accompanied by a high concentration of L-lactate in plasma (P(L-lactate))...
  47. Liu C, Gao G, Zhang Y, Wang L, Wang J, Song Y. The naked-eye detection of NH(3) -HCl by polyaniline-infiltrated TiO(2) inverse opal photonic crystals. Macromol Rapid Commun. 2012;33:380-5 pubmed publisher
    ..The naked-eye detection of NH(3) and HCl vapors can be realized by the reversible color change of the PC film, which is of importance for chemical and biological sensors...
  48. Lefler J, Ivey M. Ion chromatography detection of fluoride in calcium carbonate. J Chromatogr Sci. 2011;49:582-8 pubmed
    ..Solid samples are dissolved in hydrochloric acid, pretreated to remove the majority of the chloride ions, and then analyzed using IC...
  49. Miftodei A, Stefanache A, Spac A, Dorneanu V. Spectrometric determination of total antioxidant activity in chlorpromazine radical cation - ascorbic acid system. Rev Med Chir Soc Med Nat Iasi. 2013;117:806-11 pubmed
    ..Through univalent oxidation chlorpromazine forms a colored and relatively stable radical cation with maximum absorbance at 525 nm, considered a redox mediator in a number of b iochemical reactions...
  50. Yalinca Z, Mohammed D, Hadi J, Yilmaz E. Effect of CaCO₃/HCl pretreatment on the surface modification of chitin gel beads via graft copolymerization of 2-hydroxy ethyl methacrylate and 4-vinylpyridine. Int J Biol Macromol. 2016;82:208-16 pubmed publisher
    ..Significant improvement on the swelling capacities of chitin based gel beads in aqueous acidic, basic and neutral media was obtained. An account of the pros and cons of the system has been presented. ..
  51. Jin S, Zhang G, Zhang P, Li F, Fan S, Li J. Thermo-chemical pretreatment and enzymatic hydrolysis for enhancing saccharification of catalpa sawdust. Bioresour Technol. 2016;205:34-9 pubmed publisher
    ..7% comparing to the control. This study indicates that the thermo-Ca(OH)2 pretreatment is ideal for the saccharification of catalpa sawdust and that catalpa sawdust is a promising raw material for biofuel. ..
  52. Bai C, Zhu L, Shen F, Qi X. Black liquor-derived carbonaceous solid acid catalyst for the hydrolysis of pretreated rice straw in ionic liquid. Bioresour Technol. 2016;220:656-660 pubmed publisher
    ..6% TRS yield). Overall, this study provides a renewable strategy for the utilization of all components of lignocellulosic biomass. ..
  53. Varadwaj P, Varadwaj A, Peslherbe G. An electronic structure theory investigation of the physical chemistry of the intermolecular complexes of cyclopropenylidene with hydrogen halides. J Comput Chem. 2012;33:2073-82 pubmed publisher
    ..The present results reveal that the c-C(3)H(2) carbene divalent carbon can act as a proton acceptor and is responsible for the formation of hydrogen bonds in the complexes investigated...