- Mapping and sequencing information: the social context for the genomics revolution
Centre for the History of Science, Imperial College, London, United Kingdom
Endeavour 31:18-23. 2007
..The application of computing to DNA during the first half of the 1980s was crucial for this integration, fostering the emergence of genomics and ultimately the Human Genome Project.
- The sequence of the human genome
J C Venter
Celera Genomics, 45 West Gude Drive, Rockville, MD 20850, USA
Science 291:1304-51. 2001
..Less than 1% of all SNPs resulted in variation in proteins, but the task of determining which SNPs have functional consequences remains an open challenge...
- Segmental duplications: organization and impact within the current human genome project assembly
J A Bailey
Department of Genetics and Center for Human Genetics, Case Western Reserve School of Medicine and University Hospitals of Cleveland, Cleveland, Ohio 44106, USA
Genome Res 11:1005-17. 2001
..The identification and characterization of these highly duplicated regions represents an important step in the complete sequencing of a human reference genome...
- Sequencing and analysis of an Irish human genome
Conway Institute, University College Dublin, Belfield, Dublin 4, Ireland
Genome Biol 11:R91. 2010
- Human genome. A low number wins the GeneSweep Pool
Science 300:1484. 2003
- On the immortality of television sets: "function" in the human genome according to the evolution-free gospel of ENCODE
Department of Biology and Biochemistry, University of Houston, TX, USA
Genome Biol Evol 5:578-90. 2013
..The ENCODE results were predicted by one of its authors to necessitate the rewriting of textbooks. We agree, many textbooks dealing with marketing, mass-media hype, and public relations may well have to be rewritten...
- A vision for the future of genomics research
Francis S Collins
National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland 20892, USA
Nature 422:835-47. 2003
- Human genome sequencing using unchained base reads on self-assembling DNA nanoarrays
Complete Genomics, Inc, 2071 Stierlin Court, Mountain View, CA 94043, USA
Science 327:78-81. 2010
..The high accuracy, affordable cost of $4400 for sequencing consumables, and scalability of this platform enable complete human genome sequencing for the detection of rare variants in large-scale genetic studies...
- The DNA sequence of human chromosome 22
Sanger Centre, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK
Nature 402:489-95. 1999
..4 megabases, contains at least 545 genes and 134 pseudogenes, and provides the first view of the complex chromosomal landscapes that will be found in the rest of the genome...
- The diploid genome sequence of an individual human
J Craig Venter Institute, Rockville, Maryland, USA
PLoS Biol 5:e254. 2007
..These data depict a definitive molecular portrait of a diploid human genome that provides a starting point for future genome comparisons and enables an era of individualized genomic information...
- A sample selection strategy for next-generation sequencing
Chul Joo Kang
Department of Preventive Medicine, Keck School of Medicine, USC, Los Angeles, California, USA
Genet Epidemiol 36:696-709. 2012
..We then describe a variation on our algorithm that is more focused on detecting rarer variants. We demonstrate the performance of our algorithm using simulated data and data from the 1000 Genomes Project...
- The Human Genome Diversity Project: past, present and future
L Luca Cavalli-Sforza
L Luca Cavalli Sforza is at the Genetics Department, Stanford Medical School, Stanford, California 94305, USA
Nat Rev Genet 6:333-40. 2005
The Human Genome Project, in accomplishing its goal of sequencing one human genome, heralded a new era of research, a component of which is the systematic study of human genetic variation...
- "What are they going to do with the information?" Latino/Latina and African American perspectives on the Human Genome Project
Department of Health Behavior and Health Education, University of Michigan School of Public Health, Ann Arbor 48109 2029, USA
Health Educ Behav 30:151-69. 2003
..In addition, they present strategies for achieving a more equitable distribution of risks and benefits from genetic research and technology suggested by participants in these focus groups...
- Human evolution and its relevance for genetic epidemiology
Luigi Luca Cavalli-Sforza
Genetics Department, Stanford University Medical School, Stanford, California 94305 5120, USA
Annu Rev Genomics Hum Genet 8:1-15. 2007
..I have made no attempt to give a general bibliography, not even of results from the HGDP, since most authors' conclusions are still unpublished. Citations are limited to very few general concepts and articles discussed in this preface...
- The Human Genome Project and the future of diagnostics, treatment and prevention
G J B van Ommen
Department of Human and Clinical Genetics, Leiden University Medical Center, The Netherlands
J Inherit Metab Dis 25:183-8. 2002
The Human Genome Project, the mapping of our 30,000-50,000 genes and the sequencing of all of our DNA, will have major impact on biomedical research and the whole of therapeutic and preventive health care...
- What does our genome encode?
John A Stamatoyannopoulos
Departments of Genome Sciences and Medicine, University of Washington School of Medicine, Seattle, Washington 98195, USA
Genome Res 22:1602-11. 2012
..Finally, I consider prospects for the future, including maximizing the accuracy, completeness, and utility of ENCODE data for the community...
- The thousand-dollar genome. Genetic brinkmanship or personalized medicine?
EMBO Rep 8:900-3. 2007
- Inferring human colonization history using a copying model
Department of Statistics, University of Oxford, Oxford, United Kingdom
PLoS Genet 4:e1000078. 2008
..A detailed depiction of the peopling of the world is available in animated form...
- The Human Genome Project: lessons from large-scale biology
Francis S Collins
National Human Genome Research Institute, National Institutes of Health, Building 31, Room 4B09, 9000 Rockville Pike, Bethesda, MD 20892, USA
Science 300:286-90. 2003
- Ethical aspects of genome diversity research: genome research into cultural diversity or cultural diversity in genome research?
Institute for History, Philosophy and Ethics of Medicine, Johannes Gutenberg University, Mainz, Germany
Med Health Care Philos 12:25-34. 2009
- Prominent use of distal 5' transcription start sites and discovery of a large number of additional exons in ENCODE regions
Grup de Recerca en Informàtica Biomèdica, Institut Municipal d Investigació Mèdica Universitat Pompeu Fabra, 08003 Barcelona, Catalonia, Spain
Genome Res 17:746-59. 2007
- Genomics sizes up
Nature 451:234. 2008
- Sickle cell screening policies as portent: how will the human genome project affect public sector genetic services?
D D Phoenix
Department of Health Sciences, College of Nursing, Clemson University, South Carolina, USA
J Natl Med Assoc 87:807-12. 1995
The Human Genome Project holds much promise for providing dramatic improvements in our understanding of and means to diagnose and treat many diseases...
- [The Human Genome Project, genetic viability and genetic epidemiology]
Semmelweis Egyetem, Általános Orvostudományi Kar, II Belgyógyászati Klinika, Budapest
Orv Hetil 146:2575-80. 2005
The goal of the Human Genome Project to elucidate the complete sequence of the human genome has been achieved...
- What is a gene, post-ENCODE? History and updated definition
Mark B Gerstein
Program in Computational Biology and Bioinformatics, Yale University, New Haven, Connecticut 06511, USA
Genome Res 17:669-81. 2007
..It also manifests how integral the concept of biological function is in defining genes...
- Human monogenic disorders - a source of novel drug targets
Ryan R Brinkman
British Columbia Cancer Research Centre, University of British Columbia, Vancouver, British Columbia V5Z 1C3, Canada
Nat Rev Genet 7:249-60. 2006
..A large fraction of the human gene repertoire remains phenotypically uncharacterized, and is likely to encode many unanticipated and novel phenotypes that will be of interest to pharmaceutical and biotechnological drug developers...
- Scoliosis and the human genome project
Martha C Hawes
Department of Plant Sciences, Division of Plant Pathology and Microbiology, Bio5 Institute of Life Sciences, University of Arizona, Tucson, AZ 85721, USA
Stud Health Technol Inform 135:97-111. 2008
..These data can be used to identify children at high risk for developing spinal deformities and to design strategies for prevention...
- Human genome diversity: what about the other human genome project?
H T Greely
Stanford Law School, Stanford, California 94305 8610, USA
Nat Rev Genet 2:222-7. 2001
Although the Human Genome Project has been successful, the Human Genome Diversity Project, proposed in 1991, has so far failed to thrive...
- A robust approach to identifying tissue-specific gene expression regulatory variants using personalized human induced pluripotent stem cells
Je Hyuk Lee
Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America
PLoS Genet 5:e1000718. 2009
..We show that our approach to mapping cis-regulatory variants reduces in vitro experimental noise and reveals additional tissue-specific variants using skin-derived human iPS cells...
- Family physicians' perspectives on genetics and the human genome project
M D Fetters
Department of Family Medicine, University of Michigan Medical Center, University of Michigan, Ann Arbor 48109 0708, USA
Clin Genet 56:28-34. 1999
..the study was to determine family physicians' attitudes and beliefs about human genetics research and the human genome project (HGP). The design of the study involved qualitative, semi-structured interviews...
- Personal genomes in progress: from the human genome project to the personal genome project
Jeantine E Lunshof
European Centre for Public Health Genomics, FHML, Maastricht University, Maastricht, The Netherlands
Dialogues Clin Neurosci 12:47-60. 2010
..This article examines the Personal Genome Project's effort to develop a GET database as a public genomics resource broadly accessible to both researchers and research participants, while pursuing the highest standards in research ethics...
- Principal component analysis of genetic data
Nat Genet 40:491-2. 2008
- Assembly of the working draft of the human genome with GigAssembler
W J Kent
Department of Biology, University of California at Santa Cruz, Santa Cruz, California 95064, USA
Genome Res 11:1541-8. 2001
..7 billion base pairs and covering an estimated 88% of the genome that has been used for several recent studies of the genome. Here we describe the algorithm used by GigAssembler...
- Genetics. Was the Human Genome Project worth the effort?
Stephen P Daiger
Human Genetics Center, University of Texas Health Sciences Center, Houston, TX 77030, USA
Science 308:362-4. 2005
- Genomes for all
George M Church
Harvard Medical School, USA
Sci Am 294:46-54. 2006
- The human genome project is complete. How do we develop a handle for the pump?
Am J Epidemiol 157:667-73. 2003
- The Human Genome Project. Revealing the shared inheritance of all humankind
F S Collins
National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland 20892 2152, USA
Cancer 91:221-5. 2001
The information derived from the Human Genome Project, an international effort to decode the information embedded in the human genome, will revolutionize the practice of medicine in the 21st century by providing the tools to determine the ..
- Whole-genome shotgun assembly and comparison of human genome assemblies
Applied Biosystems, 45 West Gude Drive, Rockville, MD 20850, USA
Proc Natl Acad Sci U S A 101:1916-21. 2004
..The Celera results provide more order and orientation, and the consortium sequence provides better coverage of exact and nearly exact repeats...
- Toward the 1,000 dollars human genome
Simon T Bennett
Solexa Limited, Chesterford Research Park, Little Chesterford, Essex CB10 1XL, UK
Pharmacogenomics 6:373-82. 2005
..A new sequencing paradigm based on single molecules will be faster, cheaper and more sensitive, and will permit routine analysis at the whole-genome level...
- Initial sequencing and analysis of the human genome
E S Lander
Whitehead Institute for Biomedical Research, Center for Genome Research, Cambridge, Massachusetts 02142, USA
Nature 409:860-921. 2001
..We also present an initial analysis of the data, describing some of the insights that can be gleaned from the sequence...
- Implications of the Human Genome Project for medical science
F S Collins
National Human Genome Research Institute, National Institutes of Health, 31 Center Dr, MSC 2152, Bldg 31 Room 4B09, Bethesda, MD 20892 2152, USA
JAMA 285:540-4. 2001
..Genomic medicine holds the ultimate promise of revolutionizing the diagnosis and treatment of many illnesses...
- Structural genomics: beyond the human genome project
S K Burley
Howard Hughes Medical Institute, 1230 York Avenue, New York, New York 10021, USA
Nat Genet 23:151-7. 1999
With access to whole genome sequences for various organisms and imminent completion of the Human Genome Project, the entire process of discovery in molecular and cellular biology is poised to change...
- Genetic studies of human diversity in East Asia
Institute of Genetics, School of Life Sciences, Fudan University, Shanghai 200433, People s Republic of China
Philos Trans R Soc Lond B Biol Sci 362:987-95. 2007
..e. Central Asia, the Sub-continent, America and the Pacific Islands), the origin of Sino-Tibetan populations and expansion of the Chinese...
- Origins of the human genome project: why sequence the human genome when 96% of it is junk?
Stanford University Medical Center, Stanford, CA 94305, USA
Am J Hum Genet 79:603-5. 2006
- New goals for the U.S. Human Genome Project: 1998-2003
F S Collins
National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892, USA
Science 282:682-9. 1998
The Human Genome Project has successfully completed all the major goals in its current 5-year plan, covering the period 1993-98. A new plan, for 1998-2003, is presented, in which human DNA sequencing will be the major emphasis...
- The human genome project and its impact on psychiatry
W Maxwell Cowan
National Institute of Mental Health, Bethesda, Maryland 20892, USA
Annu Rev Neurosci 25:1-50. 2002
- Technology-specific error signatures in the 1000 Genomes Project data
Institute of Medical Informatics and Statistics, Christian Albrechts University, Brunswiker Str 10, 24105 Kiel, Germany
Hum Genet 130:505-16. 2011
..Our study thus highlights that different NGS platforms suit different practical applications differently well, and that NGS-based studies require stringent data quality control for their results to be valid...
- Comparative genomics: the key to understanding the Human Genome Project
M S Clark
Fugu Landmark Mapping Project, HGMP Resource Centre, Hinxton, Cambridge, UK
Bioessays 21:121-30. 1999
..Comparative genomics (with model organisms), once the poor relation of the human genome project, is starting to provide the key to unlock the DNA code.
- The human genome project and novel aspects of cytochrome P450 research
Division of Molecular Toxicology, IMM, Karolinska Institutet, SE 171 77 Stockholm, Sweden
Toxicol Appl Pharmacol 207:52-6. 2005
..Among the genes discovered by initiatives in the human genome project are CYP2R1, CYP2W1, CYP2S1, CYP2U1 and CYP3A43, the latter apparently encoding a pseudoenzyme...
- To reveal the genomes
Robert L Sinsheimer
Department of Molecular, Cellular, and Developmental Biology, University of California Santa Barbara, Santa Barbara, CA 93106 9610, USA
Am J Hum Genet 79:194-6. 2006
- What would you do if you could sequence everything?
Helicos BioSciences, One Kendall Square, Cambridge, Massachusetts 02139, USA
Nat Biotechnol 26:1125-33. 2008
It could be argued that the greatest transformative aspect of the Human Genome Project has been not the sequencing of the genome itself, but the resultant development of new technologies...
- Impact of human genome project on medical practice
G R Sridhar
Endocrine and Diabetes Centre, Visakhapatnam
J Assoc Physicians India 49:995-8. 2001
..Nearly 3.1 billion nucleotide bases were sequenced using the clone based approach of Human Genome Project Consortium and the shotgun approach of Celera...
- A new dimension for the human genome project: towards comprehensive expression maps
Department of Human Genetics, University of Newcastle upon Tyne, UK
Nat Genet 16:126-32. 1997
The current Human Genome Project is largely devoted to structural characterisation of our genome...
- Cancer and genomics
P A Futreal
Cancer Genome Project, Sanger Centre, Cambridge, UK
Nature 409:850-2. 2001
..Our experiment underscores the limited amount and variable quality of DNA sequence from cancer cells that is currently available...
- The Human Genome Project, genetics and health
Department of Medical Genetics, University of British Columbia, 222 6174 University Blvd, Vancouver, BC, V6T 1Z3 Canada
Community Genet 4:77-80. 2001
- Future potential of the Human Epigenome Project
Epigenomics AG, Kleine Präsidentenstrasse 1, 10178 Berlin, Germany
Expert Rev Mol Diagn 4:609-18. 2004
..Like single nucleotide polymorphisms, methylation variable positions will greatly advance our ability to elucidate and diagnose the molecular basis of human diseases...
- Sequencing the genome from nematode to human: changing methods, changing science
Rachel A Ankeny
Unit for History and Philosophy of Science, Carslaw F07, University of Sydney 2006, NSW, Australia
Endeavour 27:87-92. 2003
..The sequencing of the human genome is no exception. As a crucial part of the Human Genome Project, the history of genomic sequencing is typically presented as a direct result of the discoveries of the ..
- Functional genomics and its implications for molecular medicine
Department of Medicine, Medical College of Wisconsin, and Department of Pediatrics, Children s Hospital of Wisconsin, 9000 W Wisconsin Avenue, Milwaukee, WI 53226, USA
Pediatr Clin North Am 53:807-16, vii. 2006
..Ultimately how the unique genetic signature of an individual influences the risk and prognosis of disease will be the basis for individualized medicine in the years to come...
- Profile: meet exhibit I
Erika Check Hayden
Nature 451:763-5. 2008
- How the role of computing is driving new genetics' public policy
Centre for Leadership Studies, School of Business and Economics, University of Exeter, Streatham Court, Reenes Drive, Exeter EX 4 4PU, UK
Ethics Inf Technol 6:43-53. 2004
..Regarding (2), recent developments in the Human Genome Project (HGP) have shown that computers shape the practices of molecular genetics; an important example is the ..
- Bioethics, the genome, and the Jewish body
Paul Root Wolpe
Center of Bioethics, University of Pennsylvania, USA
Conserv Jud 54:14-25. 2002
- Property rights in genetic information
Richard A Spinello
Department of Operations and Strategic Management, Carroll School of Management, Boston College, Chestnut Hill, MA 02467, USA
Ethics Inf Technol 6:29-42. 2004
..This issue has new salience thanks to the Human Genome Project and "bio-prospecting" initiatives based on the aggregation of genetic information, such as the one being ..
- Human genome. Reaching their goal early, sequencing labs celebrate
Science 300:409. 2003
- [Genome network project: a national project in post-sequence era]
Tanpakushitsu Kakusan Koso 49:2986-92. 2004
- [Approach to the research of human functional genomics in China]
Da long Ma
Zhonghua Yi Xue Za Zhi 84:1497-8. 2004
- Understanding proteomics
Janet D Pierce
School of Nursing, University of Kansas Medical Center, Kansas City, KS 66160 7504, USA
Nurs Health Sci 9:54-60. 2007
..This review includes the recent discoveries regarding proteomics and its importance in the detection and treatment of disease...
- Transcriptome study in China
Ze Guang Han
Chinese National Human Genome Center at Shanghai, 250 Bi Bo Road, Zhanjiang High Tech Park, Pudong, Shanghai 201203, China
C R Biol 326:949-57. 2003
..In addition, EST sequencing for model organisms, including rat, zebrafish, Schistosoma japonicum and rice was performed, aiming at identifying genes associated with physiological and/or pathological characteristics...
- Atherosclerosis: the path from genomics to therapeutics
David T Miller
Division of Hematology, Brigham and Women s Hospital, Boston, Massachusetts 02115, USA
J Am Coll Cardiol 49:1589-99. 2007
..Resources including the Human Genome Project and the International HapMap project, major technological advances in high-throughput genotyping and ..
- Human epigenome project--up and running
PLoS Biol 1:E82. 2003
- Meetings that changed the world: Santa Fe 1986: Human genome baby-steps
Boston University, USA
Nature 455:876-7. 2008
- HapMap tagSNP transferability in multiple populations: general guidelines
Department of Human Genetics, Eccles Institute of Human Genetics, University of Utah, Salt Lake City, UT 84112, USA
Genomics 92:41-51. 2008
..In addition to our findings, we reviewed over 25 recent studies of tagSNP transferability and propose a general guideline for selecting tagSNPs from HapMap populations...
- Human genetics: Dr Watson's base pairs
Maynard V Olson
Nature 452:819-20. 2008
- Genomic databases as global public goods?
ESRC Centre for the Economic and Social Aspects of Genomics CESAGen A Lancaster Cardiff Collaboration, Lancaster University, Furness College, Lancaster, LA1 4YG, UK
Res Publica 10:123-34. 2004
..We shall argue that social and political arrangements are relevant and that recognising this opens the door to construing the use of global public goods language as a strategic one...
- Genome research: the next generation
F S Collins
National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland 20892, USA
Cold Spring Harb Symp Quant Biol 68:49-54. 2003
- The human genome sequence: impact on health care
M D Bashyam
Centre for DNA Fingerprinting and Diagnostics, Nacharam, Hyderabad, India
Indian J Med Res 117:43-65. 2003
..This review discusses all these aspects and dwells on the possible impact of the human genome sequence on human health, medicine and also health care delivery system...
- GeneLoc: exon-based integration of human genome maps
Weizmann Institute of Science, Rehovot, Israel
Bioinformatics 19:i222-4. 2003
..Despite the numerous available whole-genome mapping resources, no comprehensive, integrated map of the human genome yet exists...
- [The road toward molecular comprehension of diseases]
Ma Teresa Tusie Luna
Unidad de Biología Molecular y Medicina Genómica, Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran, Instituto de Investigaciones Biomédicas de la UNAM
Rev Invest Clin 55:143-7. 2003
- Genomic research and data-mining technology: implications for personal privacy and informed consent
Herman T Tavani
Department of Philosophy, Rivier College, Nashua, NH 03060, USA
Ethics Inf Technol 6:15-28. 2004
..social implications (ELSI) program requirements that were established to guide researchers working on the Human Genome Project (HGP)...
- Use of genome browsers to locate your favorite genes
Department of Chemistry, Purdue University, West Lafayette, IN, USA
Methods Mol Biol 338:1-7. 2006
..The example describes mapping, in the human genome, the promoter region of the NF-IL6 gene. The procedure is applicable to creating maps of the desired regions in genomes of other species available at the genome browser at UCSC...
- A haplotype map of the human genome
Physiol Genomics 13:3-9. 2003
- [Human cDNA and protein expression]
Tanpakushitsu Kakusan Koso 47:997-1002. 2002
- Practical genomics. Out of the lab, into practice
Hosp Health Netw 81:36-41, 2. 2007
..Some hospitals are pushing forward on the genomics front despite daunting obstacles, including cost, fear of misuse of data by insurers, and an inability to share data...
- Mexico launches bold genome project
Veronica Guerrero Mothelet
Nat Biotechnol 23:1030. 2005
- A navigator for human genome epidemiology
Nat Genet 40:124-5. 2008
- Genomics. Taking aim at Celera's shotgun
Science 295:1817. 2002
- On the sequencing of the human genome
Robert H Waterston
Genome Sequencing Center, Washington University, Saint Louis, MO 63108, USA
Proc Natl Acad Sci U S A 99:3712-6. 2002
Two recent papers using different approaches reported draft sequences of the human genome. The international Human Genome Project (HGP) used the hierarchical shotgun approach, whereas Celera Genomics adopted the whole-genome shotgun (WGS) ..
- International genome project launched
Erika Check Hayden
Nature 451:378-9. 2008
- The Harvard case of Xu Xiping: exploitation of the people, scientific advance, or genetic theft?
Amsterdam School of Social Science Research, University of Amsterdam, The Netherlands
New Genet Soc 24:57-78. 2005
- Plasmodium, human and Anopheles genomics and malaria
Stephen L Hoffman
Celera Genomics, 45 West Gude Drive, Rockville, Maryland 20850, USA
Nature 415:702-9. 2002
- [Gene therapy and tissue engineering in nephrology and renal transplantation]
Department of Internal Medicine and Therapeutics, Osaka University Graduate School of Medicine
Nippon Rinsho 59:65-71. 2001
b>Human genome project will be completed in 2003 and we will soon obtain the information of the whole DNA sequence of the human genome...
- [Perspectives on postgenome medicine: Gene therapy for brain tumors]
Department of Molecular Neurosurgery, Nagoya University, Graduate School of Medicine
Nippon Rinsho 59:76-80. 2001
..We have developed a cytokine gene therapy for malignant glioma since about 10 years ago. Here, we introduce both suicide gene therapies and immune gene therapies including our case(IFN-beta gene therapy)...
- [Perspectives on postgenome medicine: Gene therapy for lung cancer]
Respiratory Medicine and Translational Research Clinic, Tohoku University Hospital
Nippon Rinsho 59:81-4. 2001
..In this article, by reviewing the possible approach, an ideal combination of the future remedies is discussed...
- Owning the stuff of life
Sci Am 294:76-83. 2006
- Genomics. Genome centers push for polished draft
Science 296:1600-1. 2002
- The times they are a-changin'
Office of Biological and Environmental Research, Office of Science, US Department of Energy, 19901 Germantown Road, Germantown, Maryland 20874 1290, USA
Nature 417:589-90. 2002
- The Human Genome Project: a player's perspective
Maynard V Olson
Department of Medicine, UW Genome Center, University of Washington, Box 352145, Seattle, WA 98195, USA
J Mol Biol 319:931-42. 2002
- Planning the genome institute's future
Wendy R Uhlmann
Science 299:1515; author reply 1515. 2003
- Genomics, genetic epidemiology, and genomic medicine
Konstantinos N Lazaridis
Division of Gastroenterology and Hepatology, Center for Basic Research in Digestive Diseases, Mayo Clinic College of Medicine, 200 First Street SW, Rochester, MN 55905, USA
Clin Gastroenterol Hepatol 3:320-8. 2005
..This opportunity is the result of the recent completion of the Human Genome Project. It is anticipated that genomics will bring to physicians a powerful means to discover hereditary elements ..
- Genes, genomes and identity. Projections on matter
ESRC Centre for Genomics in Society, University of Exeter, Amory Building, Rennes Drive, Exeter EX4 4RJ, UK
New Genet Soc 23:285-99. 2004
..My analysis will show how this trend is a reactionary response to modern understandings of identities as social products and that it ignores new biomedical understandings of human bodies...
- Free genome databases finally defeat Celera
Nature 435:6. 2005