incidence

Summary

Summary: The number of new cases of a given disease during a given period in a specified population. It also is used for the rate at which new events occur in a defined population. It is differentiated from PREVALENCE, which refers to all cases, new or old, in the population at a given time.

Top Publications

  1. ncbi Global cancer statistics, 2002
    D Max Parkin
    Unit of Descriptive Epidemiology, International Agency for Research on Cancer, Lyon, France
    CA Cancer J Clin 55:74-108. 2005
  2. pmc Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin
    William C Knowler
    Diabetes Prevention Program Coordinating Center, Biostatistics Center, George Washington University, 6110 Executive Blvd, Suite 750, Rockville, MD 20852, USA
    N Engl J Med 346:393-403. 2002
  3. doi Estimates of cancer incidence and mortality in Europe in 2008
    J Ferlay
    International Agency for Research on Cancer, 150 cours Albert Thomas, 69372 Lyon Cedex 08, France
    Eur J Cancer 46:765-81. 2010
  4. ncbi Epidemiology of severe sepsis in the United States: analysis of incidence, outcome, and associated costs of care
    D C Angus
    Critical Care Medicine Division, Department of Anesthesiology and Critical Care Medicine, and the Center for Research on Health Care, University of Pittsburgh, Pittsburgh, PA, USA
    Crit Care Med 29:1303-10. 2001
  5. ncbi Patterns of cancer incidence, mortality, and prevalence across five continents: defining priorities to reduce cancer disparities in different geographic regions of the world
    Farin Kamangar
    Nutritional Epidemiology and Biostatistics Branches, Division of Cancer Epidemiology and Genetics, National Institutes of Health, Department of Health and Human Services, Rockville, MD 20852 7244, USA
    J Clin Oncol 24:2137-50. 2006
  6. ncbi Incidence of 2009 pandemic influenza A H1N1 infection in England: a cross-sectional serological study
    Elizabeth Miller
    Immunisation, Hepatitis and Blood Safety Department, Health Protection Agency Centre for Infections, London, UK
    Lancet 375:1100-8. 2010
  7. ncbi Prevention of type 2 diabetes mellitus by changes in lifestyle among subjects with impaired glucose tolerance
    J Tuomilehto
    Department of Epidemiology and Health Promotion, National Public Health Institute, Helsinki, Finland
    N Engl J Med 344:1343-50. 2001
  8. pmc Estimated HIV incidence in the United States, 2006-2009
    Joseph Prejean
    Division of HIV AIDS Prevention, National Center for HIV, Viral Hepatitis, STD and TB Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America
    PLoS ONE 6:e17502. 2011
  9. pmc Human papillomavirus and rising oropharyngeal cancer incidence in the United States
    Anil K Chaturvedi
    National Cancer Institute, National Institutes of Health, 6120 Executive Blvd, EPS 7072, Rockville, MD 20852, USA
    J Clin Oncol 29:4294-301. 2011
  10. pmc Dengue and dengue hemorrhagic fever
    D J Gubler
    Division of Vector Borne Infectious Diseases, Centers for Disease Control and Prevention, Fort Collins, Colorado 80522, USA
    Clin Microbiol Rev 11:480-96. 1998

Detail Information

Publications234 found, 100 shown here

  1. ncbi Global cancer statistics, 2002
    D Max Parkin
    Unit of Descriptive Epidemiology, International Agency for Research on Cancer, Lyon, France
    CA Cancer J Clin 55:74-108. 2005
    Estimates of the worldwide incidence, mortality and prevalence of 26 cancers in the year 2002 are now available in the GLOBOCAN series of the International Agency for Research on Cancer...
  2. pmc Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin
    William C Knowler
    Diabetes Prevention Program Coordinating Center, Biostatistics Center, George Washington University, 6110 Executive Blvd, Suite 750, Rockville, MD 20852, USA
    N Engl J Med 346:393-403. 2002
    ..We hypothesized that modifying these factors with a lifestyle-intervention program or the administration of metformin would prevent or delay the development of diabetes...
  3. doi Estimates of cancer incidence and mortality in Europe in 2008
    J Ferlay
    International Agency for Research on Cancer, 150 cours Albert Thomas, 69372 Lyon Cedex 08, France
    Eur J Cancer 46:765-81. 2010
    ..the relevant information for 2008 is not generally available as yet, we used statistical models to estimate incidence and mortality data for 25 cancers in 40 European countries (grouped and individually) in 2008...
  4. ncbi Epidemiology of severe sepsis in the United States: analysis of incidence, outcome, and associated costs of care
    D C Angus
    Critical Care Medicine Division, Department of Anesthesiology and Critical Care Medicine, and the Center for Research on Health Care, University of Pittsburgh, Pittsburgh, PA, USA
    Crit Care Med 29:1303-10. 2001
    To determine the incidence, cost, and outcome of severe sepsis in the United States.
  5. ncbi Patterns of cancer incidence, mortality, and prevalence across five continents: defining priorities to reduce cancer disparities in different geographic regions of the world
    Farin Kamangar
    Nutritional Epidemiology and Biostatistics Branches, Division of Cancer Epidemiology and Genetics, National Institutes of Health, Department of Health and Human Services, Rockville, MD 20852 7244, USA
    J Clin Oncol 24:2137-50. 2006
    Efforts to reduce global cancer disparities begin with an understanding of geographic patterns in cancer incidence, mortality, and prevalence...
  6. ncbi Incidence of 2009 pandemic influenza A H1N1 infection in England: a cross-sectional serological study
    Elizabeth Miller
    Immunisation, Hepatitis and Blood Safety Department, Health Protection Agency Centre for Infections, London, UK
    Lancet 375:1100-8. 2010
    Knowledge of the age-specific prevalence of immunity from, and incidence of infection with, 2009 pandemic influenza A H1N1 virus is essential for modelling the future burden of disease and the effectiveness of interventions such as ..
  7. ncbi Prevention of type 2 diabetes mellitus by changes in lifestyle among subjects with impaired glucose tolerance
    J Tuomilehto
    Department of Epidemiology and Health Promotion, National Public Health Institute, Helsinki, Finland
    N Engl J Med 344:1343-50. 2001
    ..Whether type 2 diabetes can be prevented by interventions that affect the lifestyles of subjects at high risk for the disease is not known...
  8. pmc Estimated HIV incidence in the United States, 2006-2009
    Joseph Prejean
    Division of HIV AIDS Prevention, National Center for HIV, Viral Hepatitis, STD and TB Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America
    PLoS ONE 6:e17502. 2011
    ..Previously, CDC estimated HIV incidence in the United States in 2006 as 56,300 (95% CI: 48,200-64,500)...
  9. pmc Human papillomavirus and rising oropharyngeal cancer incidence in the United States
    Anil K Chaturvedi
    National Cancer Institute, National Institutes of Health, 6120 Executive Blvd, EPS 7072, Rockville, MD 20852, USA
    J Clin Oncol 29:4294-301. 2011
    Recent increases in incidence and survival of oropharyngeal cancers in the United States have been attributed to human papillomavirus (HPV) infection, but empirical evidence is lacking.
  10. pmc Dengue and dengue hemorrhagic fever
    D J Gubler
    Division of Vector Borne Infectious Diseases, Centers for Disease Control and Prevention, Fort Collins, Colorado 80522, USA
    Clin Microbiol Rev 11:480-96. 1998
    ..A major challenge for public health officials in all tropical areas of the world is to develop and implement sustainable prevention and control programs that will reverse the trend of emergent dengue hemorrhagic fever...
  11. ncbi Incidence and outcomes of acute lung injury
    Gordon D Rubenfeld
    Division of Pulmonary and Critical Care Medicine, Harborview Medical Center, Seattle, WA 98104 2499, USA
    N Engl J Med 353:1685-93. 2005
    ..Despite recent advances in our understanding of the mechanism and treatment of acute lung injury, its incidence and outcomes in the United States have been unclear.
  12. ncbi Increasing incidence of thyroid cancer in the United States, 1973-2002
    Louise Davies
    VA Outcomes Group, Department of Veterans Affairs Medical Center, White River Junction, VT 05009, USA
    JAMA 295:2164-7. 2006
    Increasing cancer incidence is typically interpreted as an increase in the true occurrence of disease but may also reflect changing pathological criteria or increased diagnostic scrutiny...
  13. pmc Epidemiology and etiology of childhood pneumonia
    Igor Rudan
    Croatian Centre for Global Health, University of Split Medical School, Split, Croatia
    Bull World Health Organ 86:408-16. 2008
    Childhood pneumonia is the leading single cause of mortality in children aged less than 5 years. The incidence in this age group is estimated to be 0.29 episodes per child-year in developing and 0...
  14. ncbi Male circumcision for HIV prevention in men in Rakai, Uganda: a randomised trial
    Ronald H Gray
    Johns Hopkins University, Bloomberg School of Public Health, Baltimore, MD 21215, USA
    Lancet 369:657-66. 2007
    Ecological and observational studies suggest that male circumcision reduces the risk of HIV acquisition in men. Our aim was to investigate the effect of male circumcision on HIV incidence in men.
  15. ncbi The epidemiology of sepsis in the United States from 1979 through 2000
    Greg S Martin
    Division of Pulmonary, Allergy, and Critical Care, Department of Medicine, Emory University School of Medicine, Atlanta, USA
    N Engl J Med 348:1546-54. 2003
    ..there is limited epidemiologic information about the demography of sepsis or about the temporal changes in its incidence and outcome...
  16. pmc Annual report to the nation on the status of cancer, 1975-2006, featuring colorectal cancer trends and impact of interventions (risk factors, screening, and treatment) to reduce future rates
    Brenda K Edwards
    Surveillance Research Program, Division of Cancer Control and Population Sciences, National Cancer Institute, Bethesda, Maryland 20892 8315, USA
    Cancer 116:544-73. 2010
    ..This year's report includes trends in colorectal cancer (CRC) incidence and death rates and highlights the use of microsimulation modeling as a tool for interpreting past trends and ..
  17. ncbi An estimate of the worldwide prevalence and disability associated with osteoporotic fractures
    O Johnell
    Department of Orthopaedics, Malmo University Hospital, Malmo, Sweden
    Osteoporos Int 17:1726-33. 2006
    ..The aim of this study was to quantify the global burden of osteoporotic fracture worldwide...
  18. ncbi Global epidemiology of oral and oropharyngeal cancer
    Saman Warnakulasuriya
    Department of Oral Medicine and Experimental Oral Pathology, King s College Dental Institute, Bessemer Road, London SE5 9RS, UK
    Oral Oncol 45:309-16. 2009
    This review presents data on incidence, mortality, survival and trends in cancers of the lip, oral cavity and oropharynx using available recent data sources around the world...
  19. doi Incidence trends for childhood type 1 diabetes in Europe during 1989-2003 and predicted new cases 2005-20: a multicentre prospective registration study
    Christopher C Patterson
    Epidemiology Research Group, Centre for Public Health, Queen s University Belfast, Belfast, UK
    Lancet 373:2027-33. 2009
    The incidence of type 1 diabetes in children younger than 15 years is increasing. Prediction of future incidence of this disease will enable adequate fund allocation for delivery of care to be planned...
  20. doi Global patterns of cancer incidence and mortality rates and trends
    Ahmedin Jemal
    Surveillance and Health Policy Research Department, American Cancer Society, 250 Williams Street Northwest, Atlanta, GA 30303 1002, USA
    Cancer Epidemiol Biomarkers Prev 19:1893-907. 2010
    While incidence and mortality rates for most cancers (including lung, colorectum, female breast, and prostate) are decreasing in the United States and many other western countries, they are increasing in several less developed and ..
  21. doi Global epidemiology of meningococcal disease
    Lee H Harrison
    Infectious Diseases Epidemiology Research Unit, University of Pittsburgh School of Medicine and Graduate School of Public Health, 521 Parran Hall, 130 DeSoto Street, Pittsburgh, PA 15261, United States
    Vaccine 27:B51-63. 2009
    ..By far the highest incidence of meningococcal disease occurs in the meningitis belt of sub-Saharan Africa...
  22. pmc The worldwide incidence of preterm birth: a systematic review of maternal mortality and morbidity
    Stacy Beck
    Department of Obstetrics and Gynecology, University of Michigan, Ann Arbor, USA
    Bull World Health Organ 88:31-8. 2010
    To analyse preterm birth rates worldwide to assess the incidence of this public health problem, map the regional distribution of preterm births and gain insight into existing assessment strategies.
  23. ncbi The growing burden of tuberculosis: global trends and interactions with the HIV epidemic
    Elizabeth L Corbett
    Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, England, UK
    Arch Intern Med 163:1009-21. 2003
    ..The increasing global burden of tuberculosis (TB) is linked to human immunodeficiency virus (HIV) infection...
  24. ncbi Permutation tests for joinpoint regression with applications to cancer rates
    H J Kim
    Syracuse University, Department of Mathematics, 215 Carnegie Building, Syracuse University, Syracuse, NY 13244 1150, USA
    Stat Med 19:335-51. 2000
    The identification of changes in the recent trend is an important issue in the analysis of cancer mortality and incidence data...
  25. pmc The incidence of co-morbidities related to obesity and overweight: a systematic review and meta-analysis
    Daphne P Guh
    Centre for Health Evaluation and Outcome Sciences, St Paul s Hospital, BC, Canada
    BMC Public Health 9:88. 2009
    ..The primary objective of this study is to provide an estimate of the incidence of each co-morbidity related to obesity and overweight using a meta-analysis.
  26. ncbi Clinical epidemiology of inflammatory bowel disease: Incidence, prevalence, and environmental influences
    Edward V Loftus
    Inflammatory Bowel Disease Clinic, Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota 55905, USA
    Gastroenterology 126:1504-17. 2004
    Although the incidence and prevalence of ulcerative colitis and Crohn's disease are beginning to stabilize in high-incidence areas such as northern Europe and North America, they continue to rise in low-incidence areas such as southern ..
  27. pmc Diabetes and cancer: a consensus report
    Edward Giovannucci
    Department of Nutrition, Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, USA
    Diabetes Care 33:1674-85. 2010
    Epidemiologic evidence suggests that cancer incidence is associated with diabetes as well as certain diabetes risk factors and diabetes treatments...
  28. pmc Cancer statistics in Korea: incidence, mortality and survival in 2006-2007
    Kyu Won Jung
    The Korea Central Cancer Registry, National Cancer Center, Goyang, Korea
    J Korean Med Sci 25:1113-21. 2010
    Cancer has been the leading cause of death in Korea. Korea is facing a very rapid change and increase in cancer incidence, which draws much attention in public health...
  29. ncbi Gestational diabetes and the incidence of type 2 diabetes: a systematic review
    Catherine Kim
    Division of General Internal Medicine, University of Michigan, Ann Arbor, Michigan 48109, USA
    Diabetes Care 25:1862-8. 2002
    ..To examine factors associated with variation in the risk for type 2 diabetes in women with prior gestational diabetes mellitus (GDM)...
  30. pmc The global burden of typhoid fever
    John A Crump
    Foodborne and Diarrheal Diseases Branch, Division of Bacterial and Mycotic Diseases, National Center for Infectious Diseases, MS A 38, Centers for Disease Control and Prevention, 1600 Clifton Road, Atlanta, GA 30333, USA
    Bull World Health Organ 82:346-53. 2004
    ..To use new data to make a revised estimate of the global burden of typhoid fever, an accurate understanding of which is necessary to guide public health decisions for disease control and prevention efforts...
  31. ncbi Primary liver cancer: worldwide incidence and trends
    F Xavier Bosch
    Epidemiology and Cancer Registration Unit, IDIBELL Institut Català d Oncologia, Avda Gran Via s n, Km 2 7 08907 L Hospitalet de Llobregat, Barcelona, Spain
    Gastroenterology 127:S5-S16. 2004
    ..Rates of liver cancer in men are typically 2 to 4 times higher than in women. The incidence of primary liver cancer is increasing in several developed countries, including the United States, and the ..
  32. doi Incidence estimate of nonmelanoma skin cancer in the United States, 2006
    Howard W Rogers
    Advanced Dermatology, 111 Salem Turnpike, Norwich, CT 06360, USA
    Arch Dermatol 146:283-7. 2010
    To estimate the incidence of nonmelanoma skin cancer (NMSC) in the US population in 2006 and secondarily to indicate trends in numbers of procedures for skin cancer treatment.
  33. ncbi A predominantly clonal multi-institutional outbreak of Clostridium difficile-associated diarrhea with high morbidity and mortality
    Vivian G Loo
    Department of Microbiology, McGill University Health Center, Montreal, Que, Canada
    N Engl J Med 353:2442-9. 2005
    In March 2003, several hospitals in Quebec, Canada, noted a marked increase in the incidence of Clostridium difficile-associated diarrhea.
  34. ncbi Breast and ovarian cancer risks due to inherited mutations in BRCA1 and BRCA2
    Mary Claire King
    Departments of Medicine and Genome Sciences, University of Washington, Seattle, WA 98195, USA
    Science 302:643-6. 2003
    ..Lifetime risks of ovarian cancer were 54% for BRCA1 and 23% for BRCA2 mutation carriers. Physical exercise and lack of obesity in adolescence were associated with significantly delayed breast cancer onset...
  35. pmc The relationship between anti-merozoite antibodies and incidence of Plasmodium falciparum malaria: A systematic review and meta-analysis
    Freya J I Fowkes
    The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia
    PLoS Med 7:e1000218. 2010
    ..However, published evidence of the protective effect of these antibodies is conflicting...
  36. ncbi Strategies for mitigating an influenza pandemic
    Neil M Ferguson
    Department of Infectious Disease Epidemiology, Faculty of Medicine, Imperial College London, St Mary s Campus, Norfolk Place, London W2 1PG, UK
    Nature 442:448-52. 2006
    ..Estimates of policy effectiveness will change if the characteristics of a future pandemic strain differ substantially from those seen in past pandemics...
  37. ncbi The Indian Diabetes Prevention Programme shows that lifestyle modification and metformin prevent type 2 diabetes in Asian Indian subjects with impaired glucose tolerance (IDPP-1)
    A Ramachandran
    Diabetes Research Centre, M V Hospital for Diabetes, WHO Collaborating Centre for Research, Education and Training in Diabetes, Royapuram, Chennai, India
    Diabetologia 49:289-97. 2006
    ..In a prospective community-based study, we tested whether the progression to diabetes could be influenced by interventions in native Asian Indians with IGT who were younger, leaner and more insulin resistant than the above populations...
  38. pmc Efficacy of quadrivalent HPV vaccine against HPV Infection and disease in males
    Anna R Giuliano
    Risk Assessment, Detection, and Intervention Program, H Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA
    N Engl J Med 364:401-11. 2011
    ..We report on the safety of a quadrivalent vaccine (active against HPV types 6, 11, 16, and 18) and on its efficacy in preventing the development of external genital lesions and anogenital HPV infection in boys and men...
  39. ncbi Lifetime risk for development of atrial fibrillation: the Framingham Heart Study
    Donald M Lloyd-Jones
    Department of Preventive Medicine, Feinberg School of Medicine, Northwestern University Feinberg School of Medicine, 680 N Lake Shore Drive, Suite 1102, Chicago, IL, 60611, USA
    Circulation 110:1042-6. 2004
    ..Atrial fibrillation (AF) is the most common cardiac dysrhythmia and a source of considerable morbidity and mortality, but lifetime risk for AF has not been estimated...
  40. pmc Hepatocellular carcinoma incidence, mortality, and survival trends in the United States from 1975 to 2005
    Sean F Altekruse
    Division of Cancer Control and Population Sciences, and the Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD 20892 8316, USA
    J Clin Oncol 27:1485-91. 2009
    Hepatocellular carcinoma (HCC) is the third leading cause of cancer mortality worldwide. Incidence rates are increasing in the United States...
  41. pmc Antidiabetic therapies affect risk of pancreatic cancer
    Donghui Li
    Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA
    Gastroenterology 137:482-8. 2009
    ..We investigated the effect of antidiabetic therapies on the risk of pancreatic cancer...
  42. ncbi The diabetes risk score: a practical tool to predict type 2 diabetes risk
    Jaana Lindström
    Department of Epidemiology and Health Promotion, National Public Health Institute, Helsinki, Finland
    Diabetes Care 26:725-31. 2003
    ..Interventions to prevent type 2 diabetes should be directed toward individuals at increased risk for the disease. To identify such individuals without laboratory tests, we developed the Diabetes Risk Score...
  43. pmc Secular trends in the incidence of hip and other osteoporotic fractures
    C Cooper
    The MRC Lifecourse Epidemiology Unit, Southampton General Hospital, University of Southampton, Southampton SO16 6YD, UK
    Osteoporos Int 22:1277-88. 2011
    ..Substantial geographic variation has been noted in the incidence of hip fracture throughout the world, and estimates of recent incidence trends have varied widely...
  44. doi Induced abortion: incidence and trends worldwide from 1995 to 2008
    Gilda Sedgh
    Guttmacher Institute, New York, NY, USA
    Lancet 379:625-32. 2012
    Data of abortion incidence and trends are needed to monitor progress toward improvement of maternal health and access to family planning. To date, estimates of safe and unsafe abortion worldwide have only been made for 1995 and 2003.
  45. ncbi Secular trends in incidence of atrial fibrillation in Olmsted County, Minnesota, 1980 to 2000, and implications on the projections for future prevalence
    Yoko Miyasaka
    Division of Cardiovascular Disease and Internal Medicine, Mayo Clinic, Rochester, Minnesota, USA
    Circulation 114:119-25. 2006
    Limited data exist on trends in incidence of atrial fibrillation (AF). We assessed the community-based trends in AF incidence for 1980 to 2000 and provided prevalence projections to 2050.
  46. ncbi Estimates of the cancer incidence and mortality in Europe in 2006
    J Ferlay
    International Agency for Research on Cancer, 150 cours Albert Thomas, 69372 Lyon Cedex 08, France
    Ann Oncol 18:581-92. 2007
    Monitoring the evolution of the cancer burden in Europe is of great value. Estimates of the cancer burden in Europe have been published for 2004 and estimates are now being presented for cancer incidence and mortality in Europe for 2006.
  47. pmc Longitudinal study of infectious intestinal disease in the UK (IID2 study): incidence in the community and presenting to general practice
    Clarence C Tam
    Department of Infectious Disease Epidemiology, Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London WC1E 7HT, UK
    Gut 61:69-77. 2012
    To estimate, overall and by organism, the incidence of infectious intestinal disease (IID) in the community, presenting to general practice (GP) and reported to national surveillance.
  48. ncbi The incidence of congenital heart disease
    Julien I E Hoffman
    Department of Pediatrics and the Cardiovascular Research Institute, University of California, San Francisco, California 94143, USA
    J Am Coll Cardiol 39:1890-900. 2002
    This study was designed to determine the reasons for the variability of the incidence of congenital heart disease (CHD), estimate its true value and provide data about the incidence of specific major forms of CHD...
  49. pmc Quantifying the burden of disease: the technical basis for disability-adjusted life years
    C J Murray
    Harvard Center for Population and Development Studies, Cambridge, MA 02138
    Bull World Health Organ 72:429-45. 1994
    ..Assigned to each class is a severity weight between 0 and 1. Finally, a three percent discount rate is used in the calculation of DALYs. The formula for calculating DALYs based on these assumptions is provided...
  50. doi Assessment of baseline age-specific antibody prevalence and incidence of infection to novel influenza A/H1N1 2009
    P Hardelid
    Centre for Infections, Health Protection Agency, London, UK
    Health Technol Assess 14:115-92. 2010
    ..in the population of England prior to arrival of the pandemic strain virus in the UK and (2) the age-specific incidence of infection by month as the pandemic progressed by measuring increases in the proportion of individuals with ..
  51. ncbi Decline in the AIDS and death rates in the EuroSIDA study: an observational study
    A Mocroft
    Royal Free Centre for HIV Medicine and Department of Primary Care and Population Sciences, Royal Free and University College Medical School, London, UK
    Lancet 362:22-9. 2003
    ..Since the introduction of highly active antiretroviral therapy (HAART), little is known about whether changes in HIV-1 mortality and morbidity rates have been sustained. We aimed to assess possible changes in these rates across Europe...
  52. pmc Cancer incidence and mortality in relation to body mass index in the Million Women Study: cohort study
    Gillian K Reeves
    Cancer Epidemiology Unit, University of Oxford, Oxford OX3 7LF
    BMJ 335:1134. 2007
    To examine the relation between body mass index (kg/m2) and cancer incidence and mortality.
  53. pmc Global estimate of the incidence of clinical pneumonia among children under five years of age
    Igor Rudan
    Department of Medical Stastistics, Epidemiology and Medical Infomatics, School of Public Health Andrija Stampar, Zagreb, Croatia
    Bull World Health Organ 82:895-903. 2004
    ..In this paper we aim to estimate the worldwide incidence of clinical pneumonia in young children.
  54. ncbi Worldwide stroke incidence and early case fatality reported in 56 population-based studies: a systematic review
    Valery L Feigin
    National Research Centre for Stroke, Applied Neurosciences and Neurorehabilitation, School of Rehabilitation and Occupation Studies, AUT University, North Shore Campus, AA254, Northcote 0627, Auckland 1142, New Zealand
    Lancet Neurol 8:355-69. 2009
    This systematic review of population-based studies of the incidence and early (21 days to 1 month) case fatality of stroke is based on studies published from 1970 to 2008...
  55. ncbi Perinatal depression: a systematic review of prevalence and incidence
    Norma I Gavin
    RTI International, 3040 Cornwallis Road, PO Box 12194, Research Triangle Park, NC 27709 2194, USA
    Obstet Gynecol 106:1071-83. 2005
    We systematically review evidence on the prevalence and incidence of perinatal depression and compare these rates with those of depression in women at non-childbearing times.
  56. doi Future of cancer incidence in the United States: burdens upon an aging, changing nation
    Benjamin D Smith
    Radiation Oncology Flight, Wilford Hall Medical Center, Lackland Air Force Base, 2200 Bergquist Dr, Ste 1, TX 78236, USA
    J Clin Oncol 27:2758-65. 2009
    ..Although cancer incidence varies by age and race, the impact of demographic changes on cancer incidence has not been fully characterized...
  57. pmc Malaria in Brazil: an overview
    Joseli Oliveira-Ferreira
    Laboratório de Pesquisa em Malária, Instituto Oswaldo Cruz, FIOCRUZ, Pavilhão Leônidas Deane 5 degrees andar, Av Brasil 4365, Manguinhos, Rio de Janeiro, RJ CEP 21 045 900, RJ Brazil
    Malar J 9:115. 2010
    ..Although the main mosquito vector (Anopheles darlingi) is present in about 80% of the country, currently the incidence of malaria in Brazil is almost exclusively (99,8% of the cases) restricted to the region of the Amazon Basin, ..
  58. ncbi Selected major risk factors and global and regional burden of disease
    Majid Ezzati
    Risk, Resources and Environmental Management Division, Resources for the Future, Washington, DC, USA
    Lancet 360:1347-60. 2002
    ..Our aim was to estimate the contributions of selected major risk factors to global and regional burden of disease in a unified framework...
  59. doi Identification of hot spots of malaria transmission for targeted malaria control
    Teun Bousema
    Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, Keppel Street, London, United Kingdom
    J Infect Dis 201:1764-74. 2010
    ..This heterogeneity creates opportunities for targeted interventions but only if hot spots of malaria transmission can be easily identified...
  60. doi Increasing incidence and prevalence of the inflammatory bowel diseases with time, based on systematic review
    Natalie A Molodecky
    Department of Medicine, University of Calgary, Calgary, Alberta, Canada
    Gastroenterology 142:46-54.e42; quiz e30. 2012
    We conducted a systematic review to determine changes in the worldwide incidence and prevalence of ulcerative colitis (UC) and Crohn's disease (CD) in different regions and with time.
  61. doi Prostate cancer incidence and mortality trends in 37 European countries: an overview
    F Bray
    Cancer Information Section, International Agency for Research on Cancer, Lyon, France
    Eur J Cancer 46:3040-52. 2010
    Prostate cancer has emerged as the most frequent cancer amongst men in Europe, with incidence increasing rapidly over the past two decades...
  62. ncbi Fasting serum glucose level and cancer risk in Korean men and women
    Sun Ha Jee
    Department of Epidemiology and Health Promotion, Graduate School of Public Health, Yonsei University, Seoul, Korea
    JAMA 293:194-202. 2005
    ..Diabetes is a serious and costly disease that is becoming increasingly common in many countries. The role of diabetes as a cancer risk factor remains unclear...
  63. ncbi Rising incidence of hepatocellular carcinoma in the United States
    H B El-Serag
    Veterans Affairs Medical Center and the University of New Mexico, Albuquerque 87108, USA
    N Engl J Med 340:745-50. 1999
    ..data from the Surveillance, Epidemiology, and End Results (SEER) data base to determine the age-adjusted incidence of hepatocellular carcinoma from 1976 to 1995, data from the U.S...
  64. ncbi Rates of HIV-1 transmission per coital act, by stage of HIV-1 infection, in Rakai, Uganda
    Maria J Wawer
    Heilbrun Department of Population and Family Health, Columbia University Mailman School of Public Health, New York, New York 10032, USA
    J Infect Dis 191:1403-9. 2005
    ..We estimated rates of human immunodeficiency virus (HIV)-1 transmission per coital act in HIV-discordant couples by stage of infection in the index partner...
  65. ncbi The incidence and severity of adverse events affecting patients after discharge from the hospital
    Alan J Forster
    University of Ottawa, F654 1053 Carling Avenue, Ottawa, Ontario K1Y 4E9, Canada
    Ann Intern Med 138:161-7. 2003
    ..Studies of hospitalized patients identify safety as a significant problem, but few data are available regarding injuries occurring after discharge. Patients may be vulnerable during this transition period...
  66. ncbi Incidence and prevalence of idiopathic pulmonary fibrosis
    Ganesh Raghu
    University of Washington Medical Center, Seattle, WA 98195 6522, USA
    Am J Respir Crit Care Med 174:810-6. 2006
    ..Idiopathic pulmonary fibrosis is a chronic interstitial lung disease of unknown etiology; its epidemiology in the United States has not been well characterized...
  67. pmc Trends in tuberculosis incidence and their determinants in 134 countries
    C Dye
    Stop TB Department, World Health Organization, Geneva, Switzerland
    Bull World Health Organ 87:683-91. 2009
    To determine whether differences in national trends in tuberculosis incidence are attributable to the variable success of control programmes or to biological, social and economic factors.
  68. pmc Impact of intermittent preventive treatment with sulphadoxine-pyrimethamine targeting the transmission season on the incidence of clinical malaria in children in Mali
    Alassane Dicko
    Malaria Research and Training Center, Departments of Epidemiology of Parasitic Diseases, Faculty of Medicine Pharmacy and Dentistry, University of Bamako, P O Box 1805, Bamako, Mali
    Malar J 7:123. 2008
    ..that intermittent preventive malaria treatment (IPT) in infants in areas of stable malaria transmission reduces malaria and severe anaemia incidence. However in most areas malaria morbidity and mortality remain high in older children.
  69. ncbi Population-based studies on incidence, survival rates, and genetic alterations in astrocytic and oligodendroglial gliomas
    Hiroko Ohgaki
    Pathology Group, International Agency for Research on Cancer HO, F 69372, Lyon, France
    J Neuropathol Exp Neurol 64:479-89. 2005
    ..This review summarizes data on incidence rates, survival, and genetic alterations from population-based studies of astrocytic and oligodendrogliomas that ..
  70. ncbi Herpes simplex virus 2 infection increases HIV acquisition in men and women: systematic review and meta-analysis of longitudinal studies
    Esther E Freeman
    Infectious Disease Epidemiology Unit, London School of Hygiene and Tropical Medicine, UK
    AIDS 20:73-83. 2006
    ..To estimate the sex-specific effect of herpes simplex virus type 2 (HSV-2) on the acquisition of HIV infection...
  71. ncbi Hepatocellular carcinoma in cirrhosis: incidence and risk factors
    Giovanna Fattovich
    Department of Gastroenterology, University of Verona, Verona, Italy
    Gastroenterology 127:S35-50. 2004
    ..Hepatitis C virus (HCV) infection is associated with the highest HCC incidence in persons with cirrhosis, occurring twice as commonly in Japan than in the West (5-year cumulative incidence, ..
  72. ncbi New testing strategy to detect early HIV-1 infection for use in incidence estimates and for clinical and prevention purposes
    R S Janssen
    Division of HIV AIDS Prevention, National Center for HIV, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    JAMA 280:42-8. 1998
    Differentiating individuals with early human immunodeficiency virus 1 (HIV-1) infection from those infected for longer periods is difficult but important for estimating HIV incidence and for purposes of clinical care and prevention.
  73. ncbi Nosocomial bloodstream infections in US hospitals: analysis of 24,179 cases from a prospective nationwide surveillance study
    Hilmar Wisplinghoff
    Department of Internal Medicine, Medical College of Virginia Campus, Virginia Commonwealth University, Richmond, USA
    Clin Infect Dis 39:309-17. 2004
    ..Nosocomial bloodstream infections (BSIs) are important causes of morbidity and mortality in the United States...
  74. ncbi Carotid-artery intima and media thickness as a risk factor for myocardial infarction and stroke in older adults. Cardiovascular Health Study Collaborative Research Group
    D H O'Leary
    Department of Radiology, Tufts New England Medical Center, Boston, MA, USA
    N Engl J Med 340:14-22. 1999
    ..We studied the associations between the thickness of the carotid-artery intima and media and the incidence of new myocardial infarction or stroke in persons without clinical cardiovascular disease.
  75. ncbi Incidence and mortality of venous thrombosis: a population-based study
    I A Naess
    Department of Cancer Research and Molecular Medicine, Faculty of Medicine, Norwegian University of Science and Technology NTNU, Trondheim, Norway
    J Thromb Haemost 5:692-9. 2007
    Estimates of the incidence of venous thrombosis (VT) vary, and data on mortality are limited.
  76. ncbi Travelling waves in the occurrence of dengue haemorrhagic fever in Thailand
    Derek A T Cummings
    Department of Geography and Environmental Engineering, Johns Hopkins University, Baltimore, Maryland 21218, USA
    Nature 427:344-7. 2004
    ..An understanding of the spatial-temporal pattern of DHF incidence would aid the allocation of resources to combat these epidemics...
  77. pmc Age-specific incidence of A/H1N1 2009 influenza infection in England from sequential antibody prevalence data using likelihood-based estimation
    Marc Baguelin
    Immunisation, Hepatitis and Blood Safety Department, Health Protection Agency, London, United Kingdom
    PLoS ONE 6:e17074. 2011
    Estimating the age-specific incidence of an emerging pathogen is essential for understanding its severity and transmission dynamics...
  78. doi Effect of human rotavirus vaccine on severe diarrhea in African infants
    Shabir A Madhi
    Department of Science and Technology National Research Foundation Vaccine Preventable Diseases, University of the Witwatersrand, Johannesburg, South Africa
    N Engl J Med 362:289-98. 2010
    ..Rotavirus is the most common cause of severe gastroenteritis among young children worldwide. Data are needed to assess the efficacy of the rotavirus vaccine in African children...
  79. ncbi The case for expanding access to highly active antiretroviral therapy to curb the growth of the HIV epidemic
    Julio S G Montaner
    British Columbia Centre for Excellence in HIV AIDS, Providence Health Care, University of British Columbia, Vancouver, Canada
    Lancet 368:531-6. 2006
  80. pmc Effect of herpes simplex suppression on incidence of HIV among women in Tanzania
    Deborah Watson-Jones
    London School of Hygiene and Tropical Medicine, London
    N Engl J Med 358:1560-71. 2008
    ..This study tested the hypothesis that HSV-2 suppressive therapy reduces the risk of HIV acquisition...
  81. ncbi Quantitative detection of increasing HIV type 1 antibodies after seroconversion: a simple assay for detecting recent HIV infection and estimating incidence
    Bharat S Parekh
    Division of AIDS, STD, TB Laboratory Research, and Division of HIV AIDS Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
    AIDS Res Hum Retroviruses 18:295-307. 2002
    ..The assay was further validated in African specimens (subtypes A, C, and D) where the observed incidence was within 10% of the expected incidence...
  82. ncbi Five-year risk of progression of primary angle closure to primary angle closure glaucoma: a population-based study
    Ravi Thomas
    LV Prasad Eye Institute, LV Prasad Marg, Banjara Hills, Hyderabad, Andhra Pradesh 500 034, India
    Acta Ophthalmol Scand 81:480-5. 2003
    ..To report the 5-year progression to primary angle closure glaucoma (PACG) in a population-based cohort of primary angle closure (PAC) subjects...
  83. pmc Determination of the Plasmodium vivax relapse pattern in Camopi, French Guiana
    Matthieu Hanf
    Centre d Investigation Clinique Epidémiologie Clinique Antilles Guyane CIC EC Inserm 802, Centre Hospitalier de Cayenne, Guyane Francaise
    Malar J 8:278. 2009
    ..As in others endemic areas, it is important to specify the pattern of vivax malaria relapses and to try to discriminate efficiently re-infections from relapses...
  84. ncbi Buenos Aires cohort of men who have sex with men: prevalence, incidence, risk factors, and molecular genotyping of HIV type 1
    Marcela Segura
    Centro Nacional de Referencia para el SIDA, Departamento de Microbiologia, Parasitologia e Inmunologia, Facultad de Medicina, Universidad de Buenos Aires, Buenos Aires, Argentina
    AIDS Res Hum Retroviruses 23:1322-9. 2007
    The prevalence, incidence, risk factors, and molecular genotyping of HIV-1 infection among men who have sex with men (MSM) were assessed through a prospective cohort study...
  85. ncbi Modelling of malaria temporal variations in Iran
    Ali Akbar Haghdoost
    Physiology Research Centre, Kerman University of Medical Science, Kerman, Iran
    Trop Med Int Health 13:1501-8. 2008
    ..To model the temporal variations in malaria episodes in a hypo-endemic area of Iran and to assess the feasibility of an epidemic early warning system...
  86. pmc Prediction model for prevalence and incidence of advanced age-related macular degeneration based on genetic, demographic, and environmental variables
    Johanna M Seddon
    Ophthalmic Epidemiology and Genetics Service, Tufts University School of Medicine and Tufts Medical Center, Boston, Massachusetts 02111, USA
    Invest Ophthalmol Vis Sci 50:2044-53. 2009
    The joint effects of genetic, ocular, and environmental variables were evaluated and predictive models for prevalence and incidence of AMD were assessed.
  87. ncbi The incidence and risk factors of hepatocellular carcinoma in patients with nonalcoholic steatohepatitis
    Mustafa S Ascha
    Department of Gastroenterology and Hepatology, The Cleveland Clinic, Cleveland, OH 44195, USA
    Hepatology 51:1972-8. 2010
    ..The aims of this study were to (1) estimate the incidence of HCC in patients with NASH-related cirrhosis, (2) compare incidence in NASH-related cirrhosis with hepatitis C ..
  88. pmc Incidence of hospital admissions and severe outcomes during the first and second waves of pandemic (H1N1) 2009
    Melissa Helferty
    Centre for Immunization and Respiratory Infectious Diseases, Public Health Agency of Canada, Ottawa, Ont, Canada
    CMAJ 182:1981-7. 2010
    ..We compared the incidence of hospital admissions and severe outcomes (admission to intensive care unit [ICU] and death) during the two ..
  89. ncbi Therapy-related leukemia and myelodysplasia: susceptibility and incidence
    Giuseppe Leone
    Istituto di Ematologia, Universita Cattolica S Cuore, L go A Gemelli, 1, 00168 Rome, Italy
    Haematologica 92:1389-98. 2007
    ..In all cases the risk of t-MDS/AML drops sharply by 10 years after treatment...
  90. pmc Association of glycaemia with macrovascular and microvascular complications of type 2 diabetes (UKPDS 35): prospective observational study
    I M Stratton
    Diabetes Trials Unit, Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Radcliffe Infirmary, Oxford OX2 6HE
    BMJ 321:405-12. 2000
    ..To determine the relation between exposure to glycaemia over time and the risk of macrovascular or microvascular complications in patients with type 2 diabetes...
  91. ncbi Diabetes in Ontario: determination of prevalence and incidence using a validated administrative data algorithm
    Janet E Hux
    Institute for Clinical Evaluative Sciences, Toronto, Canada
    Diabetes Care 25:512-6. 2002
    ..We linked physician service claims (PSCs) and hospital discharge abstracts (HDAs) to determine diabetes prevalence and incidence.
  92. doi Increasing incidence of differentiated thyroid cancer in the United States, 1988-2005
    Amy Y Chen
    Emory University, Atlanta, GA, USA
    Cancer 115:3801-7. 2009
    Studies have reported an increasing incidence of thyroid cancer since 1980. One possible explanation for this trend is increased detection through more widespread and aggressive use of ultrasound and image-guided biopsy...
  93. ncbi Incidence, predictors at admission, and impact of worsening renal function among patients hospitalized with heart failure
    Daniel E Forman
    Section of Cardiology, Boston Medical Center, Boston, Massachusetts 02188, USA
    J Am Coll Cardiol 43:61-7. 2004
    ..The goal of this study was to determine the prevalence of worsening renal function (WRF) among hospitalized heart failure (HF) patients, clinical predictors of WRF, and hospital outcomes associated with WRF...
  94. doi Insulin glargine use and short-term incidence of malignancies-a population-based follow-up study in Sweden
    J M Jonasson
    Division of Clinical Cancer Epidemiology, Department of Oncology, Onkologiskt centrum, Sahlgrenska Academy, 41345, Gothenburg, Sweden
    Diabetologia 52:1745-54. 2009
    ..In the light of a report suggesting that insulin glargine may increase cancer occurrence, the EASD asked us to perform this study...
  95. pmc Estimation of HIV incidence in the United States
    H Irene Hall
    Division of HIV AIDS Prevention, Centers for Disease Control and Prevention, 1600 Clifton Rd NE, Atlanta, GA 30333, USA
    JAMA 300:520-9. 2008
    b>Incidence of human immunodeficiency virus (HIV) in the United States has not been directly measured. New assays that differentiate recent vs long-standing HIV infections allow improved estimation of HIV incidence.
  96. ncbi The epidemiology of genital human papillomavirus infection
    Helen Trottier
    Department of Oncology, McGill University, Montreal, Canada
    Vaccine 24:S1-15. 2006
    ..This shift in research focus coincides with a shift in cancer prevention techniques towards immunization with HPV vaccines and HPV testing of precancerous lesions...
  97. doi Incidence trends for human papillomavirus-related and -unrelated oral squamous cell carcinomas in the United States
    Anil K Chaturvedi
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA
    J Clin Oncol 26:612-9. 2008
    ..HPV) on the epidemiology of oral squamous cell carcinomas (OSCCs) in the United States, we assessed differences in patient characteristics, incidence, and survival between potentially HPV-related and HPV-unrelated OSCC sites.
  98. pmc Effect of a fall in malaria transmission on morbidity and mortality in Kilifi, Kenya
    Wendy P O'Meara
    Kenya Medical Research Institute, Centre for Geographic Medicine Research Wellcome Trust Collaborative Program, Kilifi, Kenya Fogarty International Center, National Institutes of Health, Bethesda, MD, USA
    Lancet 372:1555-62. 2008
    ..We aimed to assess the epidemiological characteristics of malaria in Kilifi, Kenya, during a period of decreasing transmission intensity...
  99. doi Decrease of the incidence of human and canine visceral leishmaniasis after dog vaccination with Leishmune in Brazilian endemic areas
    Clarisa B Palatnik-de-Sousa
    Department of General Microbiology, Institute of Microbiology Prof Paulo de Góes, Federal University of Rio de Janeiro UFRJ, Rio de Janeiro, RJ, Brazil
    Vaccine 27:3505-12. 2009
    ..We also analyzed the possible additive effect of Leishmune vaccination over dog culling, on the decrease of the incidence of CVL and VL in two Brazilian endemic areas, from 2004 to 2006...
  100. doi Estrogen plus progestin and breast cancer incidence and mortality in postmenopausal women
    Rowan T Chlebowski
    Los Angeles Biomedical Research Institute at Harbor UCLA Medical Center, 1124 W Carson St, Torrance, CA 90502, USA
    JAMA 304:1684-92. 2010
    ..6 (SD, 1.3) years (range, 3.7-8.6 years) and a mean follow-up of 7.9 (SD, 1.4) years, breast cancer incidence was increased among women who received combined hormone therapy...
  101. ncbi Time series analysis of dengue incidence in Rio de Janeiro, Brazil
    Paula M Luz
    Department of Epidemiology and Public Health, Yale University, New Haven, Connecticut 06511, USA
    Am J Trop Med Hyg 79:933-9. 2008
    We use the Box-Jenkins approach to fit an autoregressive integrated moving average (ARIMA) model to dengue incidence in Rio de Janeiro, Brazil, from 1997 to 2004...

Research Grants149 found, 100 shown here

  1. Bioengineering Core for Cellular and Tissue Models
    Andrew McCulloch; Fiscal Year: 2009
    ..The arrhythmia vulnerability of transgenic hearts can be assessed by the incidence of ventricular tachycardias during this protocol (Lerner et al., 2000)...
  2. Impact of Antibiotics and Vaccines on the in vivo Evolution of S. pneumoniae
    Garth Ehrlich; Fiscal Year: 2009
    ..reducing the incidence of those types, unfortunately other nonvaccine types have arisen introduction a few years ago of a vaccine ..
  3. Novel TIRF microscopy analyzing trafficking & signaling at the cell cortex
    Derek Toomre; Fiscal Year: 2009
    ..Consistent with the recovery act's goal, this funding will provide full-time summer employment for 4 undergraduate students and accelerate scientific achievement of the parent DP2 award...
  4. Understanding the Cognitive Impact of Early Life Epilepsy
    Frances Jensen; Fiscal Year: 2009
    ..abstract_text> ..
  5. Social Determinants of the Autism Epidemic
    Peter Bearman; Fiscal Year: 2009
    ..New analysis models for intercalating spatial and social network data are developed. These models where appropriate are extended to a wide range of developmental disorders that have increased rapidly in prevalence. ..
  6. PROGRAM DEVELOPMENT CORE
    PERRY SINGLETON; Fiscal Year: 2009
    ..First, the difference between the expected and realized values of marriage increases as the ex ante incidence of disability onset declines;intuitively, the likelihood of divorce is greater if the disability onset is ..
  7. Pancreas Cancer Specialized Program of Research Excelle*
    Anton Wellstein; Fiscal Year: 2006
    ..Both men and women will be included in numbers proportionate to the incidence of the disease and there are adequate plans for the inclusion of minority populations...
  8. Chymase-Mediated MMP Activation in Ishemia Reperfusion Injury
    LOUIS JOSEPH DELL'ITALIA; Fiscal Year: 2013
    ..response to the onset of chest pain coupled with the widespread use of statins and other drugs have reversed the incidence of ST elevation/nonST elevation MI from 70%/30% in the early 1990's to 30%/70% today...
  9. Chymase-Mediated MMP Activation in Ishemia Reperfusion Injury
    LOUIS DELL ITALIA; Fiscal Year: 2009
    ..response to the onset of chest pain coupled with the widespread use of statins and other drugs have reversed the incidence of ST elevation/nonST elevation MI from 70%/30% in the early 1990's to 30%/70% today...
  10. Sutureless Laparoscopic Partial Nephrectomy Using Laser Tissue Welding: Preclinic
    Yasmin Wadia; Fiscal Year: 2013
    ..3% localized or 181493 patients. Although the overall incidence of RCC has been steadily increasing for the past two decades, in large part due to the increased application of ..
  11. SEER RRSS #4: Cancer in Arab American Estimating Rates and Fostering Research
    Ann Schwartz; Fiscal Year: 2009
    ..in metropolitan Detroit by developing and validating a name database and algorithm to calculate proportional incidence ratios comparing Arab Americans and non-Arab Whites. Furthermore, Drs...
  12. Pacific Southwest RCE for Biodefense & Emerging Infectious Diseases Research
    Alan G Barbour; Fiscal Year: 2010
    ..Dengue is increasing in incidence and distribution in both Asia and Latin America, and autochthonous transmission within the continental U.S...
  13. NIEHS SUPPORT OF THE AHS COHORT STUDY AT NCI
    Charles Knott; Fiscal Year: 2010
    ..Analyses on cancer incidence and other chronic diseases is continuing and a number of manuscripts focusing on cancer incidence overall, ..
  14. NCCU-LCCC Partnership in Cancer Research (2 of 2)
    HENRY SHELTON EARP; Fiscal Year: 2010
    ..abstract_text> ..
  15. NCCU-LCCC Partrnership in Cancer Research (1 of 2)
    Micheler Ricardo Richardson; Fiscal Year: 2010
    ..will be used to develop a community-based intervention (managing and triage) that will reduce disparities in ICC incidence and mortality. * Findings from this study will influence attrition rates in the parent study...
  16. MOLECULAR REGULATION IN REPRODUCTION
    Frank S French; Fiscal Year: 2010
    ..A high incidence of infertility persists among women with PCOS despite successful ovulation induction...
  17. MOLECULAR REGULATION IN REPRODUCTION
    FRANK FRENCH; Fiscal Year: 2009
    ..A high incidence of infertility persists among women with PCOS despite successful ovulation induction...
  18. Androgen Modulation of Neurodegeneration in Dopamine Neurons
    Rebecca L Cunningham; Fiscal Year: 2009
    ..Current research suggests that gender plays a role in this condition, since males have a greater incidence of PD...
  19. Etiological Studies of Gastric Carcinoma
    Pelayo Correa; Fiscal Year: 2003
    ..This neoplastic disease is second only to lung cancer in incidence and mortality worldwide. In the United States gastric cancer rates have decreased considerably...
  20. Etiological Studies of Gastric Carcinoma
    Pelayo Correa; Fiscal Year: 2005
    ..This neoplastic disease is second only to lung cancer in incidence and mortality worldwide. In the United States gastric cancer rates have decreased considerably...
  21. Development of VN/14-1 and Related Analogs for Breast Cancer Therapy
    VINCENT COLLINS OFUKA NJAR; Fiscal Year: 2010
    ..highlights the influence of vitamin A (retinol) and its active metabolite, all-trans retinoic acid (ATRA) on the incidence of breast and prostate cancers in humans...
  22. The gastric X/A-like (ghrelin) cell: A peripheral regulator of food intake
    Nils Lambrecht; Fiscal Year: 2009
    ..type in the USA, and that the 158 medical facilities include over 5 million patients, strategies to reduce the incidence of obesity and cachexia related morbidity and mortality are likely to have a beneficial impact not only on ..
  23. Autonomic, Endothelial, and Inflammatory Correlates of Sleep Duration
    MERCEDES RENEE CARNETHON; Fiscal Year: 2010
    Short sleep duration (<6 hours/night) is associated with a higher prevalence and incidence of hypertension, diabetes, and overweight/obesity, all of which can contribute to coronary heart disease...
  24. Angiotensin Adrenergic Interactions in the Kidney
    Roland Blantz; Fiscal Year: 2009
    ..requiring artificial kidney treatments or kidney transplantation, but also contributes greatly to the very high incidence of heart and circulatory disease...
  25. Angiotensin Adrenergic Interactions in the Kidney
    Roland C Blantz; Fiscal Year: 2013
    ..requiring artificial kidney treatments or kidney transplantation, but also contributes greatly to the very high incidence of heart and circulatory disease...
  26. Targeting Galectin-3 with novel drugs for treatment of eczema
    Fu Tong Liu; Fiscal Year: 2010
    ..has increased two- to three-fold during the past three decades in industrialized countries, where the current incidence in children is estimated to be 15-20%...
  27. Retinoid and Carotenoid Depletion in Patients at High-Risk for Liver Cancer
    Peter H Gann; Fiscal Year: 2010
    ..Due to the epidemic of hepatitis C in the 1960's-70's, incidence has increased;approximately 3...
  28. Prostate, Lung, Colorectal and Ovarian (PLCO) Screening Trial
    BARBARA O'BRIEN; Fiscal Year: 2013
    ..Participants will be contacted annually to determine current health status. Follow up includes ascertainment of adverse medical outcomes, cancer incidence, cause of death, and mortality impact.
  29. Prostate, Lung, Colorectal and Ovarian (PLCO) Screening Trial
    Mona Fouad; Fiscal Year: 2013
    ..Participants will be contacted annually to determine current health status. Follow up includes ascertainment of adverse medical outcomes, cancer incidence, cause of death, and mortality impact.
  30. Natural History and Prevention of Viral Hepatitis Among Alaska Natives
    BRIAN JAMES MCMAHON; Fiscal Year: 2013
    ..B immunization strategies for infants, children, adolescents and adults have significantly decreased the incidence and prevalence of acute and chronic hepatitis B infection...
  31. Intracavitary Hemostatic Agent for Non-compressible Hemorrhage
    Maja Nowakowski; Fiscal Year: 2010
    ..PUBLIC HEALTH RELEVANCE: In an age of speed, civil violence and armed conflicts, the incidence of penetrating and blunt injuries to the abdomen has been on the increase. On average, 41...
  32. Intracavitary Hemostatic Agent for Non-compressible Hemorrhage
    Maja Nowakowski; Fiscal Year: 2010
    ..PUBLIC HEALTH RELEVANCE: In an age of speed, civil violence and armed conflicts, the incidence of penetrating and blunt injuries to the abdomen has been on the increase. On average, 41...
  33. Reactive (AA)Amyloidosis
    Merrill D Benson; Fiscal Year: 2013
    ..Veterans with paraplegia often have chronic infections such as osteomyelitis and, therefore, have an increased incidence of AA amyloidosis...
  34. Development of VN/14-1 and Related Analogs for Breast Cancer Therapy
    VINCENT COLLINS OFUKA NJAR; Fiscal Year: 2013
    ..highlights the influence of vitamin A (retinol) and its active metabolite, all-trans retinoic acid (ATRA) on the incidence of breast and prostate cancers in humans...
  35. Prospective studies of cancer etiology and prevention in Shanghai and Singapore
    Jian Min Yuan; Fiscal Year: 2013
    ..The findings of the proposed study will have great impact on reducing incidence and mortality of lung and liver cancers in humans.
  36. Impact of the P479L Variant in CPT1A on Infant Mortality in Alaska
    David M Koeller; Fiscal Year: 2010
    ..newborn screening by tandem mass spectrometry (MS/MS), which led to the identification of an unexpectedly high incidence of carnitine palmitoyltransferase 1A (CPT1A) deficiency, a rare disorder of fatty acid oxidation...
  37. Prospective studies of cancer etiology and prevention in Shanghai and Singapore
    Jian Min Yuan; Fiscal Year: 2010
    ..The findings of the proposed study will have great impact on reducing incidence and mortality of lung and liver cancers in humans.
  38. Metabolic Engineering of Bacteria for Cancer Immunotherapy by Gamma Delta T Cells
    Craig T Morita; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): In the United States and throughout the world, cancer incidence and mortality has increased dramatically in both developed and developing nations. Cancer causes ~13% of human deaths with 7...
  39. The Role of Cul4A in Genome Stability and Cancer Development
    Liang You; Fiscal Year: 2010
    ..Approximately 3,000 patients are diagnosed with mesothelioma in the United States annually and the incidence of this tumor is predicted to increase over the next decade in both Europe and developing nations...
  40. Targeting aberrant epigenetics by nanomedicine
    Shujun Liu; Fiscal Year: 2010
    ..In the United States, the incidence of this disease is rising with the aging of general population, and previous studies demonstrated that ..
  41. NF Center: from animal models to therapeutics
    Luis F Parada; Fiscal Year: 2010
    ..PUBLIC HEALTH RELEVANCE: Neurofibromatosis type 1 is an incurable disease with an incidence of 1 in 3,500 live births...
  42. Triazole hypersensitivity in Candida albicans
    Neeraj Chauhan; Fiscal Year: 2009
    There has been a steady increase in the incidence of fungal infections over the past few decades, primarily due to the AIDS pandemic...
  43. Chemoprophylaxis for HIV Prevention in Men
    Robert Grant; Fiscal Year: 2009
    ..Recruitment will be derived from 3 cities in Peru that had the highest incidence of HIV-1 infection in two recent surveys, have the required infrastructure to support a closely monitored ..
  44. Safety and PK Study in Hepatic Impairment Patients
    Weizhong Cai; Fiscal Year: 2009
    ..are expected to triple over the next decade as a result of the hepatitis C epidemic and the growing incidence of liver disease associated with non-alcoholic steatohepatitis...
  45. Safety and PK Study in Hepatic Impairment Patients
    Weizhong Cai; Fiscal Year: 2010
    ..are expected to triple over the next decade as a result of the hepatitis C epidemic and the growing incidence of liver disease associated with non-alcoholic steatohepatitis...
  46. Effect of diet & commensal bacteria on diabetes outcome in NOD mouse
    Li Wen; Fiscal Year: 2009
    ..by environmental factors as a) there is a significant discordance in T1D outcome in identical twins and b) the incidence of T1D is much higher in the Western world...
  47. Effect of diet & commensal bacteria on diabetes outcome in NOD mouse
    Li Wen; Fiscal Year: 2010
    ..by environmental factors as a) there is a significant discordance in T1D outcome in identical twins and b) the incidence of T1D is much higher in the Western world...
  48. Partnering with Community Health Centers to Prevent ECC
    Nancy R Kressin; Fiscal Year: 2011
    ..Recent research has documented two efficacious strategies for reducing ECC incidence. First, there is compelling evidence from several randomized controlled trials that fluoride varnish (FV) ..
  49. Biomarkers of Metabolic and Vascular Risk in Obesity
    VASAN S RAMACHANDRAN; Fiscal Year: 2010
    ..and vascular dysfunction, will distinguish obesity subphenotypes cross-sectionally, and prospectively predict incidence of diabetes, dyslipidemia, hypertension (HTN) and cardiovascular disease (CVD)...
  50. Biomarkers of Metabolic and Vascular Risk in Obesity
    Vasan Ramachandran; Fiscal Year: 2009
    ..and vascular dysfunction, will distinguish obesity subphenotypes cross-sectionally, and prospectively predict incidence of diabetes, dyslipidemia, hypertension (HTN) and cardiovascular disease (CVD)...
  51. PRIMARY HIV PREVENTION IN PREGNANT AND LACTATING UGANDAN WOMEN:A RANDOMIZED TRIAL
    Jaco Homsy; Fiscal Year: 2011
    ..shows that these women are at continuous risk of HIV acquisition during pregnancy and breastfeeding with HIV incidence rates ranging between 2 and 17 infections per 100 person years...
  52. The Effect of Aflatoxin Regulation on Global Liver Cancer Risk
    Felicia Wu; Fiscal Year: 2010
    ..provide decision- makers information on how to set foodborne aflatoxin standards that reduce global liver cancer incidence. Liver cancer (hepatocellular carcinoma) is the 3rd-leading cause of cancer deaths worldwide, with an increasing ..
  53. Epidemiology and Etiology of Hospitalized Pneumonia in Children
    Krow Ampofo; Fiscal Year: 2010
    ..Although the burden of pneumonia in children is well appreciated, recent data on the incidence and etiology of pneumonia in children are few...
  54. Epidemiology and Etiology of Hospitalized Pneumonia in Children
    Krow Ampofo; Fiscal Year: 2009
    ..Although the burden of pneumonia in children is well appreciated, recent data on the incidence and etiology of pneumonia in children are few...
  55. Epidemiology and Etiology of Hospitalized Pneumonia in Children
    Krow Ampofo; Fiscal Year: 2010
    ..Although the burden of pneumonia in children is well appreciated, recent data on the incidence and etiology of pneumonia in children are few...
  56. Combined raman spectroscopy-optical tomagraphy for complete diagnosis of skin can
    Anita Mahadevan Jansen; Fiscal Year: 2009
    The incidence of skin cancer has been on the rise in recent years and as in most cancers, early diagnosis and thorough treatment (i.e., complete resection) are the keys to gain a favorable prognosis...
  57. SEER RRSS #5 - Constructing Geographic Areas in GIS for Cancer Data Analysis
    Vivien Chen; Fiscal Year: 2009
    ..The analysis of cancer incidence often suffers from the small population problem manifested in unreliable rate estimates, sensitivity to missing ..
  58. GENERAL MORTALITY & CANCER INCIDENCE IN FL PESTICIDE APP
    Lora Fleming; Fiscal Year: 1993
    ..The proposed study will be retrospective cohort analyses of the cancer incidence and general mortality, with a nested (synthetic) case control study of cancer incidence, among a cohort of the ..
  59. NAFLD in T2DM: Prevalence in Hispanics and Role of Treatment
    Kenneth Cusi; Fiscal Year: 2009
    ..Lifespan is not only shortened by liver-related morbidity, but also by a higher incidence of cardiovascular disease (Targher et al, 2007)...
  60. Lactoferrin Enhances Growth and Reduces Nosocomial Infection in Preterm Infants
    Karel Petrak; Fiscal Year: 2009
    ..The overall incidence of prospectively studied NIs in hospitalized neonates has been reported to be 10.8 NI/100 patients...
  61. Attenuating the retinal and CNS adverse effects of vigabatrin with NKCC1 inhibito
    Frances Jensen; Fiscal Year: 2009
    ..Infantile spasms is a subgroup of epilepsy and has an incidence of approximately 1 per 2000 live births, with seizures being refractory and if untreated leads to greater than a ..
  62. Attenuating the retinal and CNS adverse effects of vigabatrin with NKCC1 inhibito
    Frances E Jensen; Fiscal Year: 2010
    ..Infantile spasms is a subgroup of epilepsy and has an incidence of approximately 1 per 2000 live births, with seizures being refractory and if untreated leads to greater than a ..
  63. Preventing Maternal and Neonatal Bacterial Infections in Developing Settings
    Shabir Madhi; Fiscal Year: 2007
    ..autoclaved tap- water inetnmittent vaginal washes) to detect at least a 40% reduction in the incidence of neonatal sepsis, with 80% power and 95% confidence...
  64. RRSS Evaluate Completeness Liver Cancer Reporting Under New Clinical Guidelines
    Dee West; Fiscal Year: 2011
    ..It is the third leading cause of cancer-related mortality worldwide and the incidence of HCC has been rising in the United States and Europe over the past decades. In the U.S...
  65. Rapid Response Surveillance Study #09-5 - Constructing Geographic Areas in GIS fo
    Sally L Glaser; Fiscal Year: 2009
    ..The analysis of cancer incidence often suffers from the small population problem manifested in unreliable rate estimates, sensitivity to missing ..
  66. Dietary supplement use, physical activity, body mass index, and pancreatic cancer
    Ka He; Fiscal Year: 2010
    ..Aims The goal of this study is to examine associations of various dietary supplements with pancreatic cancer incidence, using previously collected data from a large cohort study with a high proportion of supplement users...
  67. Dietary supplement use, physical activity, body mass index, and pancreatic cancer
    Jessie Satia; Fiscal Year: 2009
    ..Aims The goal of this study is to examine associations of various dietary supplements with pancreatic cancer incidence, using previously collected data from a large cohort study with a high proportion of supplement users...
  68. Chicago Community-Acquired Pneumonia Consortium
    Richard G Wunderink; Fiscal Year: 2010
    ..An accurate determination of the population-based incidence is critical to determine the opportunities for prevention, such as expansion of serotypes included in the ..
  69. Chicago Community-Acquired Pneumonia Consortium
    Richard Wunderink; Fiscal Year: 2009
    ..An accurate determination of the population-based incidence is critical to determine the opportunities for prevention, such as expansion of serotypes included in the ..
  70. Chicago Community-Acquired Pneumonia Consortium
    Richard G Wunderink; Fiscal Year: 2010
    ..An accurate determination of the population-based incidence is critical to determine the opportunities for prevention, such as expansion of serotypes included in the ..
  71. VITAMIN D AND IMMUNOMODULATION IN CORONARY ARTERY DISEASE
    Devendra K Agrawal; Fiscal Year: 2012
    ..Low levels of vitamin D have increased risks of heart disease, stroke, hypertension, and diabetes. The incidence of angiographic restenoses following balloon angioplasty/stent implantation correlates well with the incidence ..
  72. USING CLAIMS DATA FOR CANCER SURVEILLANCE
    Lynne Penberthy; Fiscal Year: 2000
    ..Because of its high incidence, devastating impact, and potential preventability, monitoring cancer epidemiology is essential...
  73. Reasons for Racial Disparities in Venous Thromboembolism
    NEIL ADRIAN ZAKAI; Fiscal Year: 2010
    ..The greatest difficulty in studying the reasons for this disparity in incidence is due in great part to a paucity of African-Americans in research studies of VTE to date, especially where risk ..
  74. USING CLAIMS DATA FOR CANCER SURVEILLANCE
    Lynne Penberthy; Fiscal Year: 1999
    ..Because of its high incidence, devastating impact, and potential preventability, monitoring cancer epidemiology is essential...
  75. Mutational Cloning in Familial Dementia and Alzheimers Disease
    Wendy Raskind; Fiscal Year: 2009
    ..Topic 08-AG-106 Cross-disease research to identify commonly targeted pathways or mechanisms between low incidence, neurogenetic disorders with high incidence, population-based disease...
  76. Mutational Cloning in Familial Dementia and Alzheimers Disease
    Wendy H Raskind; Fiscal Year: 2010
    ..Topic 08-AG-106 Cross-disease research to identify commonly targeted pathways or mechanisms between low incidence, neurogenetic disorders with high incidence, population-based disease...
  77. Diet and Gastrointestinal Cancer Risk in African Americans and Rural Africans
    STEPHEN JD O apos KEEFE; Fiscal Year: 2010
    Geographical variations in cancer incidence can be attributed to environmental causes in general, and to diet, in particular...