three dimensional imaging

Summary

Summary: The process of generating three-dimensional images by electronic, photographic, or other methods. For example, three-dimensional images can be generated by assembling multiple tomographic images with the aid of a computer, while photographic 3-D images (HOLOGRAPHY) can be made by exposing film to the interference pattern created when two laser light sources shine on an object.

Top Publications

  1. ncbi Automated manifold surgery: constructing geometrically accurate and topologically correct models of the human cerebral cortex
    B Fischl
    Nuclear Magnetic Resonance Center, Massachusetts General Hospital, Harvard Medical School, Charlestown 02129, USA
    IEEE Trans Med Imaging 20:70-80. 2001
  2. ncbi User-guided 3D active contour segmentation of anatomical structures: significantly improved efficiency and reliability
    Paul A Yushkevich
    Penn Image Computing and Science Laboratory, Department of Radiology, University of Pennsylvania, PA 19104 6274, USA
    Neuroimage 31:1116-28. 2006
  3. ncbi Tomographic molecular imaging and 3D quantification within adult mouse organs
    Tomas Alanentalo
    Umeå Center for Molecular Medicine, Umea University, S 901 87, Umea, Sweden
    Nat Methods 4:31-3. 2007
  4. ncbi A study of diffusion tensor imaging by tissue-specific, smoothing-compensated voxel-based analysis
    Jee Eun Lee
    Waisman Laboratory for Brain Imaging and Behavior, Waisman Center, Madison, WI 53705, USA
    Neuroimage 44:870-83. 2009
  5. ncbi New techniques for imaging, digitization and analysis of three-dimensional neural morphology on multiple scales
    S L Wearne
    Computational Neurobiology and Imaging Center, Mount Sinai School of Medicine, New York, NY 10029 6574, USA
    Neuroscience 136:661-80. 2005
  6. ncbi Multicell simulations of development and disease using the CompuCell3D simulation environment
    Maciej H Swat
    Biocomplexity Institute and Department of Physics, Indiana University, Bloomington, USA
    Methods Mol Biol 500:361-428. 2009
  7. ncbi Anatomically constrained region deformation for the automated segmentation of the hippocampus and the amygdala: Method and validation on controls and patients with Alzheimer's disease
    Marie Chupin
    Department of Clinical and Experimental Epilepsy, Institute of Neurology, UCL, UK
    Neuroimage 34:996-1019. 2007
  8. ncbi Image-based computational fluid dynamics modeling in realistic arterial geometries
    David A Steinman
    Imaging Research Laboratories, The John P Robarts Research Institute, The University of Western Ontario, London, Canada
    Ann Biomed Eng 30:483-97. 2002
  9. ncbi Magnitude and role of wall shear stress on cerebral aneurysm: computational fluid dynamic study of 20 middle cerebral artery aneurysms
    Masaaki Shojima
    Department of Neurosurgery, Faculty of Medicine, University of Tokyo, Japan
    Stroke 35:2500-5. 2004
  10. ncbi Aneurysm growth occurs at region of low wall shear stress: patient-specific correlation of hemodynamics and growth in a longitudinal study
    Loic Boussel
    Department of Radiology, VA Medical Center, San Francisco, USA 94121, USA
    Stroke 39:2997-3002. 2008

Research Grants

  1. MICROSCOPY & IMAGE ANALYSIS OF UNSTAINED MACROMOLECULES
    Timothy Baker; Fiscal Year: 1993
  2. A New Integrated Endoscope System
    LIH LIN; Fiscal Year: 2009
  3. A New Integrated Endoscope System
    Lih Y Lin; Fiscal Year: 2010
  4. Three-Dimensional Imaging of Whole Cells by Using X-ray Diffraction Microscopy
    Jianwei Miao; Fiscal Year: 2010
  5. Three-Dimensional Imaging of Whole Cells by Using X-ray Diffraction Microscopy
    Jianwei Miao; Fiscal Year: 2009
  6. Posterior glenohumeral capsule influence on shoulder impingement
    JOHN BORSTAD; Fiscal Year: 2007
  7. DEVELOPING VIRTUAL COLONOSCOPY FOR CANCER SCREENING
    JEROME LIANG; Fiscal Year: 2007
  8. Focal Structure-Function Relationships in Macular Layers from 3D Spectral OCT
    Milan Sonka; Fiscal Year: 2009
  9. Focal Structure-Function Relationships in Macular Layers from 3D Spectral OCT
    MILAN contact SONKA; Fiscal Year: 2010
  10. 3-D Imaging Technique for Applications in Anthropome
    PEISEN HUANG; Fiscal Year: 2002

Detail Information

Publications220 found, 100 shown here

  1. ncbi Automated manifold surgery: constructing geometrically accurate and topologically correct models of the human cerebral cortex
    B Fischl
    Nuclear Magnetic Resonance Center, Massachusetts General Hospital, Harvard Medical School, Charlestown 02129, USA
    IEEE Trans Med Imaging 20:70-80. 2001
    ....
  2. ncbi User-guided 3D active contour segmentation of anatomical structures: significantly improved efficiency and reliability
    Paul A Yushkevich
    Penn Image Computing and Science Laboratory, Department of Radiology, University of Pennsylvania, PA 19104 6274, USA
    Neuroimage 31:1116-28. 2006
    ..Analogous results for lateral ventricle segmentation are provided...
  3. ncbi Tomographic molecular imaging and 3D quantification within adult mouse organs
    Tomas Alanentalo
    Umeå Center for Molecular Medicine, Umea University, S 901 87, Umea, Sweden
    Nat Methods 4:31-3. 2007
    ..Using the nonobese diabetic (NOD) mouse model, we demonstrate a correlation between total islet beta-cell volume and the onset of type-1 diabetes...
  4. ncbi A study of diffusion tensor imaging by tissue-specific, smoothing-compensated voxel-based analysis
    Jee Eun Lee
    Waisman Laboratory for Brain Imaging and Behavior, Waisman Center, Madison, WI 53705, USA
    Neuroimage 44:870-83. 2009
    ..The T-SPOON method may be also applicable to other quantitative imaging maps such as T1 or T2 relaxometry, magnetization transfer, or PET tracer maps...
  5. ncbi New techniques for imaging, digitization and analysis of three-dimensional neural morphology on multiple scales
    S L Wearne
    Computational Neurobiology and Imaging Center, Mount Sinai School of Medicine, New York, NY 10029 6574, USA
    Neuroscience 136:661-80. 2005
    ....
  6. ncbi Multicell simulations of development and disease using the CompuCell3D simulation environment
    Maciej H Swat
    Biocomplexity Institute and Department of Physics, Indiana University, Bloomington, USA
    Methods Mol Biol 500:361-428. 2009
    ..This tutorial introduces Glazier-Graner-Hogeweg (GGH) multicell simulations and CompuCell3D, a simulation framework that allows users to build, test, and run GGH simulations...
  7. ncbi Anatomically constrained region deformation for the automated segmentation of the hippocampus and the amygdala: Method and validation on controls and patients with Alzheimer's disease
    Marie Chupin
    Department of Clinical and Experimental Epilepsy, Institute of Neurology, UCL, UK
    Neuroimage 34:996-1019. 2007
    ..The proposed approach provides a new framework for further developments in quantitative analyses of the pathological hippocampus and amygdala in MRI scans...
  8. ncbi Image-based computational fluid dynamics modeling in realistic arterial geometries
    David A Steinman
    Imaging Research Laboratories, The John P Robarts Research Institute, The University of Western Ontario, London, Canada
    Ann Biomed Eng 30:483-97. 2002
    ..Issues related to accuracy, precision, and modeling assumptions are also discussed...
  9. ncbi Magnitude and role of wall shear stress on cerebral aneurysm: computational fluid dynamic study of 20 middle cerebral artery aneurysms
    Masaaki Shojima
    Department of Neurosurgery, Faculty of Medicine, University of Tokyo, Japan
    Stroke 35:2500-5. 2004
    ..The magnitude and distribution of the WSS in and around human middle cerebral artery (MCA) aneurysms were analyzed using the method of computed fluid dynamics (CFD)...
  10. ncbi Aneurysm growth occurs at region of low wall shear stress: patient-specific correlation of hemodynamics and growth in a longitudinal study
    Loic Boussel
    Department of Radiology, VA Medical Center, San Francisco, USA 94121, USA
    Stroke 39:2997-3002. 2008
    ..Low wall shear stress (WSS) has been reported to have a negative effect on endothelial cells normal physiology and may be an important contributor to local remodeling of the arterial wall and to aneurysm growth and rupture...
  11. ncbi Effect of endothelial shear stress on the progression of coronary artery disease, vascular remodeling, and in-stent restenosis in humans: in vivo 6-month follow-up study
    Peter H Stone
    Cardiovascular Division, Brigham and Women s Hospital, 75 Francis St, Boston, Mass 02115, USA
    Circulation 108:438-44. 2003
    ..The endothelium controls local arterial responses by transduction of shear stress. Characterization of endothelial shear stress (ESS) may allow for prediction of progression of atherosclerosis and in-stent restenosis...
  12. ncbi Measurement of myocardial mechanics in mice before and after infarction using multislice displacement-encoded MRI with 3D motion encoding
    Wesley D Gilson
    Department of Biomedical Engineering, University of Virginia, Charlottesville, Virginia 22908, USA
    Am J Physiol Heart Circ Physiol 288:H1491-7. 2005
    ..07 +/- 0.54 degrees /mm (R = 0.96, P < 0.05). DENSE MRI can assess the 3D myocardial mechanics of the murine heart in <1 h of scan time at 4.7 T and may be applied to studies of myocardial mechanics in genetically engineered mice...
  13. ncbi Recommendations from Gynaecological (GYN) GEC-ESTRO Working Group (I): concepts and terms in 3D image based 3D treatment planning in cervix cancer brachytherapy with emphasis on MRI assessment of GTV and CTV
    Christine Haie-Meder
    Department of Radiotherapy, Brachytherapy Unit, Institut Gustave Roussy, 39 rue Camille Desmoulins, 94805 Villejuif, France
    Radiother Oncol 74:235-45. 2005
    ..Furthermore, CTV for BT is defined related to risk for recurrence: high risk CTV and intermediate risk CTV. Beside verbal descriptions detailed examples are given, partly in form of schematic drawings...
  14. ncbi Second-harmonic imaging microscopy of normal human and keratoconus cornea
    Naoyuki Morishige
    The Eye Institute, School of Medicine, University of California Irvine Medical Center, Orange, California
    Invest Ophthalmol Vis Sci 48:1087-94. 2007
    ..The purpose of this study was to evaluate the ability of second-harmonic imaging to identify differences in corneal stromal collagen organization between normal human and keratoconus corneas...
  15. ncbi Accelerating molecular modeling applications with graphics processors
    JOHN E STONE
    Beckman Institute, University of Illinois at Urbana Champaign, Urbana, IL 61801, USA
    J Comput Chem 28:2618-40. 2007
    ..In light of the performance obtained for this set of calculations, future applications of graphics processors to molecular dynamics simulations are discussed...
  16. ncbi False discovery rate revisited: FDR and topological inference using Gaussian random fields
    Justin R Chumbley
    Wellcome Trust Centre for Neuroimaging, University College London, London, UK
    Neuroimage 44:62-70. 2009
    ..We describe the nature of the problem, illustrate it with some examples and suggest a simple solution based on controlling the false discovery rate of connected excursion sets within an SPM, characterised by their volume...
  17. ncbi Detection and quantification of left atrial structural remodeling with delayed-enhancement magnetic resonance imaging in patients with atrial fibrillation
    Robert S Oakes
    Atrial Fibrillation Program, University of Utah School of Medicine, Salt Lake City, UT 84132 2400, USA
    Circulation 119:1758-67. 2009
    ..In this study, we report the utility of delayed-enhancement magnetic resonance imaging (DE-MRI) in detecting abnormal atrial tissue before radiofrequency ablation and in predicting procedural outcome...
  18. ncbi A layer-specific three-dimensional model for the simulation of balloon angioplasty using magnetic resonance imaging and mechanical testing
    Gerhard A Holzapfel
    Institute for Structural Analysis Computational Biomechanics, Graz University of Technology, Austria
    Ann Biomed Eng 30:753-67. 2002
    ....
  19. ncbi Automatic segmentation of cortical and trabecular compartments based on a dual threshold technique for in vivo micro-CT bone analysis
    Helen R Buie
    Department of Mechanical and Manufacturing Engineering, Schulich School of Engineering, University of Calgary, 2500 University Drive N W, Calgary, Alberta, Canada T2N 1N4
    Bone 41:505-15. 2007
    ..Using the same input thresholds for similar datasets assures maximal consistency while alleviating time consuming semi-automated contouring...
  20. ncbi Myocardial 3D strain calculation by combining cine displacement encoding with stimulated echoes (DENSE) and cine strain encoding (SENC) imaging
    Aaron T Hess
    Department of Human Biology, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa
    Magn Reson Med 62:77-84. 2009
    ..42 +/-0.11, -0.10 +/-0.03, and -0.21 +/-0.02, respectively. These results show that this technique is capable of reliably quantifying 3D cardiac strain...
  21. ncbi 3D MRI-based multicomponent FSI models for atherosclerotic plaques
    Dalin Tang
    Mathematical Sciences Department, Worcester Polytechnic Institute, Worcester, MA 01609, USA
    Ann Biomed Eng 32:947-60. 2004
    ..Large-scale patient studies are needed to validate the computational findings for possible plaque vulnerability assessment and rupture predictions...
  22. ncbi Globally optimal stitching of tiled 3D microscopic image acquisitions
    Stephan Preibisch
    Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany
    Bioinformatics 25:1463-5. 2009
    ..The physical coordinates provided by the microscope stage are not precise enough to allow direct reconstruction (Stitching) of the whole image from individual image stacks...
  23. ncbi Whole-heart steady-state free precession coronary artery magnetic resonance angiography
    Oliver M Weber
    Department of Radiology, University of California San Francisco, San Francisco, California 94143, USA
    Magn Reson Med 50:1223-8. 2003
    ..It is concluded that the whole-heart coronary MRA technique improves visible vessel length and facilitates high-quality coronary MRA of the complete coronary artery tree in a single measurement...
  24. ncbi Texture analysis of medical images
    G Castellano
    Neuroimage Laboratory, Faculty of Medical Sciences, State University of Campinas, Brazil
    Clin Radiol 59:1061-9. 2004
    ..In this article we clarify the principles of texture analysis and give examples of its applications, reviewing studies of the technique...
  25. ncbi Hippocampal head size associated with verbal memory performance in nondemented elderly
    V H Hackert
    Department of Epidemiology and Biostatistics, Erasmus Medical Center, Rotterdam, The Netherlands
    Neuroimage 17:1365-72. 2002
    ..06, 0.59)). Our data suggest selective involvement of the hippocampal head in verbal memory, and add to recent findings of functional segregation along the longitudinal axis of the hippocampus...
  26. ncbi Estimating linear cortical magnification in human primary visual cortex via dynamic programming
    Anqi Qiu
    Center for Imaging Science, Johns Hopkins University, Baltimore, MD 21218, USA
    Neuroimage 31:125-38. 2006
    ..The reliability of these estimates was assessed by comparing results based on data from one quadrant to those based on data from the full hemifield along with a split-half reliability analysis...
  27. ncbi Inter- and intraobserver variation in HR-CTV contouring: intercomparison of transverse and paratransverse image orientation in 3D-MRI assisted cervix cancer brachytherapy
    Primoz Petric
    Department of Radiotherapy and Radiobiology, Medical University of Vienna, Vienna, Austria
    Radiother Oncol 89:164-71. 2008
    ..To analyze agreement between target volumes, delineated by two observers on transverse (T) and paratransverse (perpendicular to the long cervical axis - PT) MR images for cervix cancer brachytherapy...
  28. ncbi Evaluation of reproducibility and reliability of 3D soft tissue analysis using 3D stereophotogrammetry
    J M Plooij
    3D Facial Imaging Research Group Nijmegen Bruges 3D FIRG, Department of Oral and Maxillofacial Surgery, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Int J Oral Maxillofac Surg 38:267-73. 2009
    ..This shows that hard tissue data are not needed to perform accurate soft tissue analysis...
  29. ncbi Direct three-dimensional myocardial strain tensor quantification and tracking using zHARP
    Khaled Z Abd-Elmoniem
    Department of Radiology and Radiological Sciences, School of Medicine, Johns Hopkins University, Baltimore, MD 21287, USA
    Med Image Anal 12:778-86. 2008
    ..The performance and accuracy of the method is demonstrated in vitro on a phantom and in vivo in four healthy adult human subjects...
  30. ncbi 3D micro-CT imaging of the postmortem brain
    Alex de Crespigny
    Athinoula A Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, MA 02129, USA
    J Neurosci Methods 171:207-13. 2008
    ..For simple measurements, such as tumor volume and non-destructive postmortem brain screening, microCT may prove to be a valuable alternative to standard histopathology or microMRI...
  31. ncbi Discriminating power of localized three-dimensional facial morphology
    Peter Hammond
    Eastman Dental Institute, University College London, London, WC1X 8LD, United Kingdom
    Am J Hum Genet 77:999-1010. 2005
    ....
  32. ncbi Analysis of barley (Hordeum vulgare) grain development using three-dimensional digital models
    Sabine Gubatz
    Leibniz Institute of Plant Genetics and Crop Plant Research IPK, Corrensstr 3, D 06466, Gatersleben, Germany
    Plant J 52:779-90. 2007
    ..At anthesis, mRNA of the protease nucellin was visualized in a distinct zone of the nucellus near the antipodal cells...
  33. ncbi An Eulerian PDE approach for computing tissue thickness
    Anthony J Yezzi
    School of Electrical and Computer Engineering, Georgia Institute of Technology, Atlanta, GA 30322, USA
    IEEE Trans Med Imaging 22:1332-9. 2003
    ..These experiments reveal very good performance and show strong potential for application in tissue thickness visualization and quantification...
  34. ncbi Morphogenesis and oncogenesis of MCF-10A mammary epithelial acini grown in three-dimensional basement membrane cultures
    Jayanta Debnath
    Department of Cell Biology, Harvard Medical School, 240 Longwood Avenue, Boston, MA 02115, USA
    Methods 30:256-68. 2003
    ....
  35. ncbi The three-dimensional micro- and nanostructure of the aortic medial lamellar unit measured using 3D confocal and electron microscopy imaging
    Mary K O'Connell
    Department of Mechanical Engineering, Stanford University, Stanford, CA, USA
    Matrix Biol 27:171-81. 2008
    ..This high resolution three-dimensional view of the aortic media reveals MLU microstructure details that suggest a highly complex and integrated mural organization that correlates with aortic mechanical properties...
  36. ncbi Wall shear stress on ruptured and unruptured intracranial aneurysms at the internal carotid artery
    L D Jou
    Department of Radiology, Baylor College of Medicine, Houston, TX 77030, USA
    AJNR Am J Neuroradiol 29:1761-7. 2008
    ..Flow impingement, greater pressure, and abnormal wall shear stress are all indications for aneurysm rupture. Characterizing wall shear stress for intracranial aneurysms at similar anatomic locations may help in understanding its role...
  37. ncbi Usefulness of three-dimensional, multidetector row CT (virtual gastroscopy and multiplanar reconstruction) in the evaluation of gastric cancer: a comparison with conventional endoscopy, EUS, and histopathology
    Suryaprakash Bhandari
    Institute for Digestive Research and Department of Radiology, Soon Chun Hyang University College of Medicine, Seoul, South Korea
    Gastrointest Endosc 59:619-26. 2004
    ..1%, 57%, and 89.5%; and 75%, 57.4%, and 89.3%. CONCLUSIONS: Three-dimensional multidetector row CT, along with virtual gastroscopy is a promising method for pre-operative evaluation of gastric cancer...
  38. ncbi Two-photon 3-D mapping of ex vivo human skin endogenous fluorescence species based on fluorescence emission spectra
    Lily H Laiho
    Massachusetts Institute of Technology, Department of Mechanical Engineering, 77 Massachusetts Avenue, NE47 276, Cambridge, Massachusetts 02139, USA
    J Biomed Opt 10:024016. 2005
    ..Luminescence species identified include tryptophan, NAD(P)H, melanin, and elastin, which are autofluorescent, and collagen that contributes to a second harmonic signal...
  39. ncbi Gastric cancer: preoperative local staging with 3D multi-detector row CT--correlation with surgical and histopathologic results
    Chiao Yun Chen
    Department of Medical Imaging, Kaohsiung Medical University, Chung Ho Memorial Hospital, 100 Tz You 1st Road, Kaohsiung, Taiwan
    Radiology 242:472-82. 2007
    ..To prospectively evaluate accuracy of multi-detector row computed tomographic (CT) images for preoperative staging of gastric cancer by using surgical and histopathologic results as reference standards...
  40. ncbi Three-dimensional coronary MR angiography performed with subject-specific cardiac acquisition windows and motion-adapted respiratory gating
    Sven Plein
    British Heart Foundation-Cardiac MRI Unit, Rm. 170, D Fl, Jubilee Building, Leeds General Infirmary, Great George Street, Leeds LS1 3EX, United Kingdom
    AJR Am J Roentgenol 180:505-12. 2003
    ....
  41. ncbi Rapid automated three-dimensional tracing of neurons from confocal image stacks
    Khalid A Al-Kofahi
    Electrical, Computer, and Systems Engineering Department, Rensselaer Polytechnic Institute, Troy, NY 12180 3590, USA
    IEEE Trans Inf Technol Biomed 6:171-87. 2002
    ..These properties make it attractive for large-scale automated tissue studies that require rapid on-line image analysis, such as high-throughput neurobiology/angiogenesis assays, and initiatives such as the Human Brain Project...
  42. ncbi Registration of 3-D intraoperative MR images of the brain using a finite-element biomechanical model
    M Ferrant
    Communications and Remote Sensing Laboratory, Universite Catholique de Louvain, Louvain la Neuve, Belgium
    IEEE Trans Med Imaging 20:1384-97. 2001
    ..Cortical surface shifts of up to 10 mm and subsurface shifts of up to 6 mm were recovered with an accuracy of 1 mm or less and 3 mm or less respectively...
  43. ncbi Mutual-information-based registration of medical images: a survey
    Josien P W Pluim
    University Medical Center Utrecht, Image Sciences Institute, Room E01 335, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands
    IEEE Trans Med Imaging 22:986-1004. 2003
    ..Comparison studies including mutual information are also considered. The paper starts with a description of entropy and mutual information and it closes with a discussion on past achievements and some future challenges...
  44. ncbi Rigid registration of 3-D ultrasound with MR images: a new approach combining intensity and gradient information
    A Roche
    INRIA Projet Epidaure, Sophia Antipolis, France
    IEEE Trans Med Imaging 20:1038-49. 2001
    ..A cross-validation study has been carried out using a number of phantom and clinical data. This indicates that the method is quite robust and that the worst registration errors are of the order of the MR image resolution...
  45. ncbi Serial registration of intraoperative MR images of the brain
    Matthieu Ferrant
    Communications and Remote Sensing Laboratory, , B-1348, Louvain-la-Neuve, Belgium
    Med Image Anal 6:337-59. 2002
    ..7+/-0.6 mm (mean+/-S.D.) for boundary surface landmarks, of 0.9+/-0.6 mm for landmarks inside the boundary surfaces, and 1.6+/-0.9 mm for landmarks in the vicinity of the tumor...
  46. ncbi Visualization of flow patterns distal to aortic valve prostheses in humans using a fast approach for cine 3D velocity mapping
    S Kozerke
    Institute of Biomedical Engineering, University of Zurich and Swiss Federal Institute of Technology, Switzerland
    J Magn Reson Imaging 13:690-8. 2001
    ..It is concluded that MR velocity mapping is a potential tool for studying 3D flow patterns evolving around heart valve prostheses in humans. J. Magn. Reson. Imaging 2001;13:690-698...
  47. ncbi eF-site and PDBjViewer: database and viewer for protein functional sites
    Kengo Kinoshita
    Graduate School of Integrated Science, Yokohama City University, 1-7-29 Suehiro-cho, Tsurumi-ku, Yokohama, 230-0045, Japan
    Bioinformatics 20:1329-30. 2004
    ..AVAILABILITY: The eF-site database and PDBjViewer are freely available from http://www.pdbj.org/eF-site/..
  48. ncbi Three-dimensional adaptive filtering in magnetic resonance angiography
    C F Westin
    Surgical Planning Laboratory, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA
    J Magn Reson Imaging 14:63-71. 2001
    ..9 dB) were observed. 3D adaptive filtering may provide an alternative to prolonging the scan time or using contrast agents in MRA when the CNR is low...
  49. ncbi Navigator-gated coronary magnetic resonance angiography using steady-state-free-precession: comparison to standard T2-prepared gradient-echo and spiral imaging
    Elmar Spuentrup
    Department of Diagnostic Radiology, Technical University of Aachen, Aachen, Germany
    Invest Radiol 38:263-8. 2003
    ..The purpose of this study was a systematic comparison of SSFP cMRA with standard T2-prepared gradient-echo and spiral cMRA...
  50. ncbi Biphasic tissue Doppler waveforms during isovolumic phases are associated with asynchronous deformation of subendocardial and subepicardial layers
    Partho P Sengupta
    Division of Cardiovascular Diseases, Mayo Clinic Rochester, 200 First St. SW, Rochester, MN 55905, USA
    J Appl Physiol 99:1104-11. 2005
    ..The results support an association between asynchronous deformation of subendocardial and subepicardial muscle fibers and the biphasic isovolumic movements observed with high-resolution tissue Doppler imaging...
  51. ncbi Value of three-dimensional US for optimizing guidance for ablating focal liver tumors
    S C Rose
    Department of Radiology, University of California Medical Center, 200 West Arbor Drive, San Diego, CA 92103, USA
    J Vasc Interv Radiol 12:507-15. 2001
    ....
  52. ncbi Improved visualization of coronary arteries using a new three-dimensional submillimeter MR coronary angiography sequence with balanced gradients
    Benedetta Giorgi
    Department of Radiology, Gasthuisberg University Hospital, Catholic University of Leuven, Herestraat 49, B-3000 Leuven, Belgium
    AJR Am J Roentgenol 179:901-10. 2002
    ....
  53. ncbi Navigator-gated free-breathing three-dimensional balanced fast field echo (TrueFISP) coronary magnetic resonance angiography
    Elmar Spuentrup
    Department of Medicine Cardiovascular Division, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts, USA
    Invest Radiol 37:637-42. 2002
    ..It is hypothesized that Balanced-FFE may be valuable for contrast enhancement in 3D free-breathing coronary MRA...
  54. ncbi Effects of noise, image resolution, and ROI definition on the accuracy of standard uptake values: a simulation study
    Ronald Boellaard
    PET Center, VU University Medical Center, Amsterdam, The Netherlands
    J Nucl Med 45:1519-27. 2004
    ..Therefore, an experimental and simulation study was performed to determine the effects of noise, image resolution, and region-of-interest (ROI) definition on the accuracy of SUVs...
  55. ncbi Nonrigid registration of 3D tensor medical data
    J Ruiz-Alzola
    Medical Technology Center, University of Las Palmas de Gran Canaria and Gran Canaria Dr Negrín Hospital, Spain
    Med Image Anal 6:143-61. 2002
    ..The feasibility of the approach is illustrated by results on synthetic and clinical data...
  56. ncbi The impact of contouring uncertainty on rectal 3D dose-volume data: results of a dummy run in a multicenter trial (AIROPROS01-02)
    Franca Foppiano
    Department of Medical Physics, National Cancer Research Institute, Genova, Italy
    Int J Radiat Oncol Biol Phys 57:573-9. 2003
    ..To estimate the impact of the uncertainty in contouring the rectum on rectal dose-volume parameters and normal tissue complication probability (NTCP) in a prospective (AIROPROS01-02) investigation about rectal toxicity...
  57. ncbi Accuracy of finite element model-based multi-organ deformable image registration
    K K Brock
    Radiation Medicine Program, Princess Margaret Hospital, University Health Network, 610 University Avenue, Toronto, Ontario, Canada M5G 2M9
    Med Phys 32:1647-59. 2005
    ....
  58. ncbi Tomographic fluorescence mapping of tumor targets
    Xavier Montet
    Center for Molecular Imaging Research, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA
    Cancer Res 65:6330-6. 2005
    ..FMT measurements can be done serially, with short imaging times and within the same live animal. The described method should be valuable for rapidly profiling biological phenomena in vivo...
  59. ncbi Design and quantitative resolution measurements of an optical virtual sectioning three-dimensional imaging technique for biomedical specimens, featuring two-micrometer slicing resolution
    Jan A N Buytaert
    University of Antwerp, Laboratory of Biomedical Physics, Department of Physics, Groenenborgerlaan 171, B 2020 Wilrijk Antwerpen, Belgium
    J Biomed Opt 12:014039. 2007
    ..We present quantitative measurements of resolution. A 3-D model reconstructed from our HROPFOS data is compared to SEM results, and the technique is demonstrated with section images and 3-D reconstructions of middle ear specimens...
  60. ncbi Three-dimensional organization of higher-plant chloroplast thylakoid membranes revealed by electron tomography
    Eyal Shimoni
    Electron Microscopy Unit, Weizman Institute of Science, Rehovot 76100, Israel
    Plant Cell 17:2580-6. 2005
    ..This highly connected morphology has important consequences for the formation and function of the thylakoid membranes as well as for their stacking/unstacking response to variations in light conditions...
  61. ncbi Drosophila brain development: closing the gap between a macroarchitectural and microarchitectural approach
    A Cardona
    Department of Molecular, Cell, and Developmental Biology, University of California at Los Angeles, Los Angeles, CA 90095, USA
    Cold Spring Harb Symp Quant Biol 74:235-48. 2009
    ..In this chapter, we introduce our efforts to reconstruct the small Drosophila larval brain and discuss our results in light of the published data on neuropile ultrastructure in other animal taxa...
  62. ncbi Fast tracking of cardiac motion using 3D-HARP
    Li Pan
    Department of Biomedical Engineering, Johns Hopkins School of Medicine, 601 N Caroline St JHOC 4240, Baltimore, MD 21287, USA
    IEEE Trans Biomed Eng 52:1425-35. 2005
    ..8605 and r2 = 0.8645, respectively. The total time required for tracking 3-D cardiac motion is approximately 10 min in a 9 timeframe tagged MRI dataset and has the potential to be much faster...
  63. ncbi State of the art of fusion of computed tomography data and optical 3D images
    E Nkenke
    Department of Oral and Maxillofacial Surgery, University of Erlangen Nuremberg, Germany
    Int J Comput Dent 10:11-24. 2007
    ..When streak artefacts are present, image fusion makes it possible to increase the quality of the data to the level of the original resolution of computed tomography without artefacts...
  64. ncbi Automated electron microscope tomography using robust prediction of specimen movements
    David N Mastronarde
    Boulder Laboratory for Three Dimensional Electron Microscopy of Cells, Department of Molecular, Cellular, and Developmental Biology, University of Colorado, Boulder, CO 80309, USA
    J Struct Biol 152:36-51. 2005
    ..It also includes tools for navigating between specimen positions and finding regions of interest...
  65. ncbi Validation and reproducibility of a high-resolution three-dimensional facial imaging system
    B Khambay
    Glasgow Dental Hospital and School, 378 Sauchiehall Street, Glasgow, G2 3JZ, UK
    Br J Oral Maxillofac Surg 46:27-32. 2008
    ..To assess the accuracy and reproducibility of a high-resolution three-dimensional imaging system (Di3D)...
  66. ncbi Picture perfect? Reliability of craniofacial anthropometry using three-dimensional digital stereophotogrammetry
    Carrie L Heike
    Department of Pediatrics, Division of Craniofacial Medicine, University of Washington and Seattle Children s Hospital, Seattle, Wash 98105 5371, USA
    Plast Reconstr Surg 124:1261-72. 2009
    ..Three-dimensional surface imaging systems offer a quick and practical method for quantifying craniofacial variation and appear to be highly reliable. However, some sources of measurement error have not yet been thoroughly evaluated...
  67. ncbi Three-dimensional imaging of Drosophila melanogaster
    Leeanne McGurk
    Medical Research Council Human Genetics Unit, Edinburgh, United Kingdom
    PLoS ONE 2:e834. 2007
    ..The data is displayed as 2D optical sections and also in 3D to provide detail on the shape and structure of the adult anatomy...
  68. ncbi Three-dimensional textural analysis of brain images reveals distributed grey-matter abnormalities in schizophrenia
    Balaji Ganeshan
    Clinical Imaging Sciences Centre, Brighton and Sussex Medical School, University of Sussex, Falmer, Brighton, UK
    Eur Radiol 20:941-8. 2010
    ....
  69. ncbi Key parameters of face shape variation in 3D in a large sample
    Martin Evison
    Forensic Science Program, University of Toronto Mississauga, Mississauga, ON, Canada
    J Forensic Sci 55:159-62. 2010
    ..We anticipate this approach will lend itself to the development of methods for analysis of variation within subject groups and the establishment of the relative uniqueness or abundance of facial measurements within them...
  70. ncbi Airflow limitation and airway dimensions in chronic obstructive pulmonary disease
    Masaru Hasegawa
    First Department of Medicine, Hokkaido University School of Medicine, N-15 W-7 Kita-ku, Sapporo 060-8638, Japan
    Am J Respir Crit Care Med 173:1309-15. 2006
    ..73 for B8). CONCLUSIONS: We are the first to use three-dimensional computed tomography to demonstrate that airflow limitation in COPD is more closely related to the dimensions of the distal (small) airways than proximal (large) airways...
  71. ncbi An efficient virtual dissection tool to create generic models for anatomical atlases
    Mei Xiao
    Department of Biochemistry and Molecular Biology, University of Calgary, Calgary, Canada
    Stud Health Technol Inform 142:426-8. 2009
    ..The technique optimizes the functionalities of existing toolkits and the resulting software package will allow biologists to build their atlases more quickly and accurately...
  72. ncbi Time-resolved 3-dimensional velocity mapping in the thoracic aorta: visualization of 3-directional blood flow patterns in healthy volunteers and patients
    Michael Markl
    Department of Radiology, Stanford University, Stanford, CA 94304, USA
    J Comput Assist Tomogr 28:459-68. 2004
    ..Various visualization tools were used to analyze blood flow patterns within a single 3-component velocity volumetric acquisition of the entire thoracic aorta..
  73. ncbi Multislice CT angiography of fenestrated endovascular stent grafting for treating abdominal aortic aneurysms: a pictorial review of the 2D/3D visualizations
    Zhonghua Sun
    Discipline of Medical Imaging, Department of Imaging and Applied Physics, Curtin University of Technology, Perth, Western Australia, Australia
    Korean J Radiol 10:285-93. 2009
    ..The potential applications of each visualization technique were explored and compared with the 2D axial images...
  74. ncbi MicroCT for comparative morphology: simple staining methods allow high-contrast 3D imaging of diverse non-mineralized animal tissues
    Brian D Metscher
    Department of Theoretical Biology, Gerd Müller, University of Vienna, Althanstrasse 14, 1090 Austria
    BMC Physiol 9:11. 2009
    ..Although osmium staining and a few other techniques have been used for contrast enhancement, generally useful methods for microCT imaging for comparative morphology are still lacking...
  75. ncbi 3D myocardial tissue tracking with slice followed cine DENSE MRI
    Bruce S Spottiswoode
    UCT MRC Medical Imaging Research Unit, University of Cape Town, South Africa
    J Magn Reson Imaging 27:1019-27. 2008
    ..To track three-dimensional (3D) myocardial tissue motion using slice followed cine displacement encoded imaging with stimulated echoes (DENSE)...
  76. ncbi Update in three-dimensional imaging in facial plastic surgery
    Carlo P Honrado
    Larrabee Center for Facial Plastic Surgery, 600 Broadway, Suite 280, Seattle, WA 98122, USA
    Curr Opin Otolaryngol Head Neck Surg 12:327-31. 2004
    ..Recent advances in technology have made three-dimensional imaging and analysis possible...
  77. ncbi Three-dimensional reconstruction allows accurate quantification and length measurements of coronary artery stenoses
    Harald Rittger
    Medizinische Klinik II, Klinikum Coburg, Coburg, Germany
    EuroIntervention 5:127-32. 2009
    ..Israel) as compared to a validated quantitative coronary angiography (QCA) system (Siemens Quantcor, Siemens Medical Solutions)...
  78. ncbi MR diagnosis of a pulmonary embolism: comparison of P792 and Gd-DOTA for first-pass perfusion MRI and contrast-enhanced 3D MRA in a rabbit model
    Shella D Keilholz
    Department of Biomedical Engineering, Emory University, Atlanta, GA, USA
    Korean J Radiol 10:447-54. 2009
    ....
  79. ncbi Fast interactive integration of cross-sectional image datasets and surface data for morphometric analysis
    Oscar Meruvia-Pastor
    Department of Biochemistry and Molecular Biology, University of Calgary, Canada
    Stud Health Technol Inform 142:183-8. 2009
    ..Our system is interactive, fully scalable and can be applied to any photographic sliced dataset, regardless of subject and reduces significantly the processing time for stack alignment...
  80. ncbi Coronary CT angiography: automatic cardiac-phase selection for image reconstruction
    Balazs Ruzsics
    Department of Radiology and Radiological Science, Medical University of South Carolina, Ashley River Tower, 25 Courtenay Dr, Charleston, SC 29401, USA
    Eur Radiol 19:1906-13. 2009
    ..The use of automatic phase finding may therefore facilitate the performance of cardiac CT and reduce human error...
  81. ncbi CATMAID: collaborative annotation toolkit for massive amounts of image data
    Stephan Saalfeld
    Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany
    Bioinformatics 25:1984-6. 2009
    ..The CATMAID interface enables synchronized navigation through multiple registered datasets even at vastly different scales such as in comparisons between optical and electron microscopy. AVAILABILITY: http://fly.mpi-cbg.de/catmaid...
  82. ncbi Segmenting and tracking the left ventricle by learning the dynamics in cardiac images
    W Sun
    Laboratory for Information and Decision Systems, Massachusetts Institute of Technology, Cambridge, MA, USA
    Inf Process Med Imaging 19:553-65. 2005
    ..We observe that our approach provides more accurate segmentations than those from static image segmentation techniques, especially when the observed data are of limited quality...
  83. ncbi A statistical parts-based model of anatomical variability
    Matthew Toews
    Centre for Intelligent Machines, McGill University, Montreal, QC H3A 2A7, Canada
    IEEE Trans Med Imaging 26:497-508. 2007
    ..Additionally, it is shown that unlike global models such as the AAM, PBM fitting is stable in the presence of unexpected, local perturbation...
  84. ncbi A deformable registration method for automated morphometry of MRI brain images in neuropsychiatric research
    Daniel Schwarz
    Masaryk University, Institute of Biostatistics and Analyses, 625 00 Brno, Czech Republic
    IEEE Trans Med Imaging 26:452-61. 2007
    ..Results of application of the method in automated spatial detection of anatomical abnormalities in first-episode schizophrenia are presented...
  85. ncbi Probabilistic brain atlas encoding using Bayesian inference
    Koen Van Leemput
    Helsinki Medical Imaging Center, Helsinki University Central Hospital, Finland
    Med Image Comput Comput Assist Interv Int Conf Med Image Comput Comput Assist Interv 9:704-11. 2006
    ..We believe extracting optimal prior probability distributions from training data is crucial in light of the central role priors play in many automated brain MRI analysis techniques...
  86. ncbi A statistical parts-based appearance model of inter-subject variability
    Matthew Toews
    Centre for Intelligent Machines, McGili University, Montreal, Canada
    Med Image Comput Comput Assist Interv 9:232-40. 2006
    ..Preliminary results indicate that the model can be used to automatically identify distinctive features for inter-subject image registration despite large changes in appearance...
  87. ncbi Morphometric analysis for pathological abnormality detection in the skull vaults of adolescent idiopathic scoliosis girls
    Lin Shi
    Department of Computer Science and Engineering, The Chinese University of Hong Kong, Shatin, N T, Hong Kong, China
    Med Image Comput Comput Assist Interv 9:175-82. 2006
    ..The results of this study specify the skull vault surface changes and shed light on building the evidence of bone formation abnormality in AIS girls...
  88. ncbi Nonrigid image registration using conditional mutual information
    Dirk Loeckx
    Medical Image Computing, Faculties of Medicine and Engineering, Katholieke Universiteit Leuven, University Hospital Gasthuisberg, Herestraat 49 bus 7003, B 3000 Leuven, Belgium
    Inf Process Med Imaging 20:725-37. 2007
    ..Moreover, cMI is compared to global MI for the registration of three patient CT/MR datasets, using overlap and centroid distance as validation measure. The best results are obtained using cMI...
  89. ncbi Active shape models for a fully automated 3D segmentation of the liver--an evaluation on clinical data
    Tobias Heimann
    Medical and Biological Informatics, German Cancer Research Center, Heidelberg
    Med Image Comput Comput Assist Interv 9:41-8. 2006
    ..The deformable model search achieves the best results, followed by the ASM search with 30 modes. Overall, statistical shape modeling delivers very promising results for a fully automated segmentation of the liver...
  90. ncbi A unified information-theoretic approach to groupwise non-rigid registration and model building
    Carole J Twining
    Imaging Science and Biomedical Engineering (ISBE, Stopford Building, University of Manchester, Manchester, UK
    Inf Process Med Imaging 19:1-14. 2005
    ....
  91. ncbi Multimodality image registration using an extensible information metric and high dimensional histogramming
    Jie Zhang
    Dept of Computer and Information Science and Engineering, University of Florida, Gainesville, FL 32611 6120, USA
    Inf Process Med Imaging 19:725-37. 2005
    ..Our results demonstrate the efficacy of the metrics and high-dimensional histogramming in affine, multimodality image registration...
  92. ncbi Multiclassifier fusion in human brain MR segmentation: modelling convergence
    Rolf A Heckemann
    Imaging Sciences Department, MRC Clinical Sciences Centre, Imperial College at Hammersmith Hospital Campus, London, UK
    Med Image Comput Comput Assist Interv Int Conf Med Image Comput Comput Assist Interv 9:815-22. 2006
    ..Fit parameters of this model are potential indicators of the quality of a given label propagation method or the consistency of the input segmentations used...
  93. ncbi Genetic algorithms for finite mixture model based voxel classification in neuroimaging
    Jussi Tohka
    Laboratory of Neuro Imaging, Department of Neurology, UCLA School of Medicine, University of California, Los Angeles, CA 90095, USA
    IEEE Trans Med Imaging 26:696-711. 2007
    ..The tissue classification results by our method are shown to be consistently more reliable and accurate than with the competing parameter estimation methods...
  94. ncbi Multiple abdominal organ segmentation: an atlas-based fuzzy connectedness approach
    Yongxin Zhou
    Department of Biomedical Engineering, Tsinghua University, Beijing 100084, China
    IEEE Trans Inf Technol Biomed 11:348-52. 2007
    ..This atlas-based segmentation method has been tested on some abdominal CT and MRI images from Chinese patients. Experimental results indicate the validity of this segmentation method for various image modalities...
  95. ncbi Probabilistic streamline q-ball tractography using the residual bootstrap
    Jeffrey I Berman
    UCSF Department of Radiology, University of California San Francisco, 185 Berry St, Suite 350, San Francisco, CA 94107, USA
    Neuroimage 39:215-22. 2008
    ..This fiber tracking algorithm is an improvement upon prior diffusion tensor methods and the q-ball data can be acquired in a clinically feasible time frame...
  96. ncbi Live-wire-based 3D segmentation method
    Wojciech Wiecławek
    Division of Biomedical Electronics, Institute of Electronics, Faculty of Automatic Control, Electronics and Computer Science, Silesian University of Technology, ul Akademicka 16, 44 100 Gliwice, Poland
    Conf Proc IEEE Eng Med Biol Soc 2007:5646-9. 2007
    ..It does not require users interaction. The method has been employed to Magnetic Resonance Imaging (MRI) and X-Ray Computed Tomography (CT) studies. Additionally, noise resistance of the 3D approach has been measured...
  97. ncbi Simulation and fully automatic multimodal registration of medical ultrasound
    Wolfgang Wein
    Imaging and Visualization Department, Siemens Corporate Research, Princeton, NJ, USA
    Med Image Comput Comput Assist Interv 10:136-43. 2007
    ..We also present the used initialization, global and local parameter optimization schemes, and validation on abdominal CTA and ultrasound imaging of 10 patients...
  98. ncbi Groupwise combined segmentation and registration for atlas construction
    Kanwal K Bhatia
    Visual Information Processing, Department of Computing, Imperial College London
    Med Image Comput Comput Assist Interv 10:532-40. 2007
    ..These have been used to quantify the growth of tissues occurring between these ages...
  99. ncbi Thoracic CT-PET registration using a 3D breathing model
    Antonio Moreno
    Ecole Nationale Supérieure des Télécommunications GET Télécom Paris, CNRS UMR 5141 LTCI Signal and Image Processing Department, Paris, France
    Med Image Comput Comput Assist Interv 10:626-33. 2007
    ..Initial results demonstrate the interest of this method to significantly improve the accuracy of multimodal volume registration for diagnosis and radiotherapy applications...
  100. ncbi Surface modeling--uncertainty estimation and visualization
    Pawel Drapikowski
    Poznan University of Technology, Institute of Control and Information Engineering, ul Piotrowo 3a, 60 965 Poznan, Poland
    Comput Med Imaging Graph 32:134-9. 2008
    ..A quality visualisation of the errors in the geometric model has been presented in the form of a colour scale, and a quantity visualisation in the form of a ribbon, whose width is proportional to the uncertainty model...
  101. ncbi Joint segmentation-registration of organs using geometric models
    Alper Ayvaci
    Department of Computer Science, Rensselaer Polytechnic Institute, 110 8th Street, Troy, NY 12180, USA
    Conf Proc IEEE Eng Med Biol Soc 2007:5251-4. 2007
    ..Furthermore, to reduce the computational cost, the algorithm is designed to run on watershed regions instead of voxels. The accuracy of the algorithm is shown on the medical examples...

Research Grants79

  1. MICROSCOPY & IMAGE ANALYSIS OF UNSTAINED MACROMOLECULES
    Timothy Baker; Fiscal Year: 1993
    ..g. by correcting for phase contrast transfer effects or by averaging very large numbers of particle images), and vii) to phase x-ray crystallographic data with models derived from density maps reconstructed from micrographs...
  2. A New Integrated Endoscope System
    LIH LIN; Fiscal Year: 2009
    ..PHS 398/2590 (Rev. 09/04, Reissued 4/2006) Page 1 Continuation Format Page ..
  3. A New Integrated Endoscope System
    Lih Y Lin; Fiscal Year: 2010
    ..PHS 398/2590 (Rev. 09/04, Reissued 4/2006) Page 1 Continuation Format Page ..
  4. Three-Dimensional Imaging of Whole Cells by Using X-ray Diffraction Microscopy
    Jianwei Miao; Fiscal Year: 2010
    ..This novel imaging technique will be applied to the localization of multiprotein complexes inside whole cells. ..
  5. Three-Dimensional Imaging of Whole Cells by Using X-ray Diffraction Microscopy
    Jianwei Miao; Fiscal Year: 2009
    ..This novel imaging technique will be applied to the localization of multiprotein complexes inside whole cells. ..
  6. Posterior glenohumeral capsule influence on shoulder impingement
    JOHN BORSTAD; Fiscal Year: 2007
    ..The findings of this research are likely to improve shoulder rehabilitation, decrease patient impairment and disability, prevent impingement, and lower health care costs. ..
  7. DEVELOPING VIRTUAL COLONOSCOPY FOR CANCER SCREENING
    JEROME LIANG; Fiscal Year: 2007
    ....
  8. Focal Structure-Function Relationships in Macular Layers from 3D Spectral OCT
    Milan Sonka; Fiscal Year: 2009
    ..This study has potentially important consequences for glaucoma, anterior ischemic neural neuropathy, and other retinal disease diagnosis and treatment. ..
  9. Focal Structure-Function Relationships in Macular Layers from 3D Spectral OCT
    MILAN contact SONKA; Fiscal Year: 2010
    ..This study has potentially important consequences for glaucoma, anterior ischemic neural neuropathy, and other retinal disease diagnosis and treatment. ..
  10. 3-D Imaging Technique for Applications in Anthropome
    PEISEN HUANG; Fiscal Year: 2002
    ..The effectiveness of lung volume reduction surgery (LVRS) will be evaluated. The technique developed in this research should have numerous other medical as well as engineering applications. ..
  11. High Resolution Multiplexed Fluorescence Tomography
    MARK JONATHAN NIEDRE; Fiscal Year: 2010
    ..We anticipate that the scanner will have many applications in biomedical research including studying disease development and response to novel therapeutics in vivo. ..
  12. Biomechanics of Spine Fracture
    TONY KEAVENY; Fiscal Year: 2007
    ..abstract_text> ..
  13. Image Reconstruction Algorithms for Optical Tomography
    JOHN SCHOTLAND; Fiscal Year: 2009
    ..We will utilize the parallel plate imaging geometry which is often employed in optical mammography. The results of this research are expected to impact the design of clinically useful instruments for noncontact optical tomography. ..
  14. Image Reconstruction Algorithms for Optical Tomography
    JOHN SCHOTLAND; Fiscal Year: 2007
    ..We will utilize the parallel plate imaging geometry which is often employed in optical mammography. The results of this research are expected to impact the design of clinically useful instruments for noncontact optical tomography. ..
  15. An Electron Microscope for the study of Complex Biological Assemblies
    MICHAEL ROSSMANN; Fiscal Year: 2006
    ..The instrument would also allow us to perform tomographic studies at about 50 A resolution on pleomorphic viruses and cell organelles that lack structural homogeneity. ..
  16. LOW-MOLECULAR WEIGHT LIGANDS FOR PROSTATE CANCER
    JOHN FRANGIONI; Fiscal Year: 2003
    ..We believe that prostate- specific, low-molecular weight ligands will someday be clinically useful reagents for improved prostate cancer detection and guided therapy. ..
  17. Ophthalmic Imaging Using Adaptive Optics and OCT
    John Werner; Fiscal Year: 2007
    The purpose of this BRP is to develop and evaluate new instrumentation that will permit unprecedented three dimensional imaging of single cells in the human retina, specifically rod and cone photoreceptors and ganglion cells...