three dimensional imaging

Summary

Summary: The process of generating three-dimensional images by electronic, photographic, or other methods. For example, three-dimensional images can be generated by assembling multiple tomographic images with the aid of a computer, while photographic 3-D images (HOLOGRAPHY) can be made by exposing film to the interference pattern created when two laser light sources shine on an object.

Top Publications

  1. ncbi Automated manifold surgery: constructing geometrically accurate and topologically correct models of the human cerebral cortex
    B Fischl
    Nuclear Magnetic Resonance Center, Massachusetts General Hospital, Harvard Medical School, Charlestown 02129, USA
    IEEE Trans Med Imaging 20:70-80. 2001
  2. ncbi Sparse MRI: The application of compressed sensing for rapid MR imaging
    Michael Lustig
    Magnetic Resonance Systems Research Laboratory, Department of Electrical Engineering, Stanford University, Stanford, California 94305 9510, USA
    Magn Reson Med 58:1182-95. 2007
  3. ncbi MicroCT for developmental biology: a versatile tool for high-contrast 3D imaging at histological resolutions
    Brian D Metscher
    Department of Theoretical Biology, University of Vienna, Vienna, Austria
    Dev Dyn 238:632-40. 2009
  4. pmc MicroCT for comparative morphology: simple staining methods allow high-contrast 3D imaging of diverse non-mineralized animal tissues
    Brian D Metscher
    Department of Theoretical Biology, Gerd Müller, University of Vienna, Althanstrasse 14, 1090 Austria
    BMC Physiol 9:11. 2009
  5. ncbi User-guided 3D active contour segmentation of anatomical structures: significantly improved efficiency and reliability
    Paul A Yushkevich
    Penn Image Computing and Science Laboratory, Department of Radiology, University of Pennsylvania, PA 19104 6274, USA
    Neuroimage 31:1116-28. 2006
  6. pmc Aneurysm growth occurs at region of low wall shear stress: patient-specific correlation of hemodynamics and growth in a longitudinal study
    Loic Boussel
    Department of Radiology, VA Medical Center, San Francisco, USA 94121, USA
    Stroke 39:2997-3002. 2008
  7. ncbi Characterizing of tissue microstructure with single-detector polarization-sensitive optical coherence tomography
    Bin Liu
    Department of Orthopedic Surgery, Brigham and Women s Hospital, Massachusetts, USA
    Appl Opt 45:4464-79. 2006
  8. ncbi New techniques for imaging, digitization and analysis of three-dimensional neural morphology on multiple scales
    S L Wearne
    Computational Neurobiology and Imaging Center, Mount Sinai School of Medicine, New York, NY 10029 6574, USA
    Neuroscience 136:661-80. 2005
  9. pmc Discriminating power of localized three-dimensional facial morphology
    Peter Hammond
    Eastman Dental Institute, University College London, London, WC1X 8LD, United Kingdom
    Am J Hum Genet 77:999-1010. 2005
  10. ncbi Effect of endothelial shear stress on the progression of coronary artery disease, vascular remodeling, and in-stent restenosis in humans: in vivo 6-month follow-up study
    Peter H Stone
    Cardiovascular Division, Brigham and Women s Hospital, 75 Francis St, Boston, Mass 02115, USA
    Circulation 108:438-44. 2003

Detail Information

Publications262 found, 100 shown here

  1. ncbi Automated manifold surgery: constructing geometrically accurate and topologically correct models of the human cerebral cortex
    B Fischl
    Nuclear Magnetic Resonance Center, Massachusetts General Hospital, Harvard Medical School, Charlestown 02129, USA
    IEEE Trans Med Imaging 20:70-80. 2001
    ....
  2. ncbi Sparse MRI: The application of compressed sensing for rapid MR imaging
    Michael Lustig
    Magnetic Resonance Systems Research Laboratory, Department of Electrical Engineering, Stanford University, Stanford, California 94305 9510, USA
    Magn Reson Med 58:1182-95. 2007
    ..Examples demonstrate improved spatial resolution and accelerated acquisition for multislice fast spin-echo brain imaging and 3D contrast enhanced angiography...
  3. ncbi MicroCT for developmental biology: a versatile tool for high-contrast 3D imaging at histological resolutions
    Brian D Metscher
    Department of Theoretical Biology, University of Vienna, Vienna, Austria
    Dev Dyn 238:632-40. 2009
    ..These methods establish microCT imaging as a useful tool for comparative developmental studies, embryo phenotyping, and quantitative modeling of development...
  4. pmc MicroCT for comparative morphology: simple staining methods allow high-contrast 3D imaging of diverse non-mineralized animal tissues
    Brian D Metscher
    Department of Theoretical Biology, Gerd Müller, University of Vienna, Althanstrasse 14, 1090 Austria
    BMC Physiol 9:11. 2009
    ..Although osmium staining and a few other techniques have been used for contrast enhancement, generally useful methods for microCT imaging for comparative morphology are still lacking...
  5. ncbi User-guided 3D active contour segmentation of anatomical structures: significantly improved efficiency and reliability
    Paul A Yushkevich
    Penn Image Computing and Science Laboratory, Department of Radiology, University of Pennsylvania, PA 19104 6274, USA
    Neuroimage 31:1116-28. 2006
    ..Analogous results for lateral ventricle segmentation are provided...
  6. pmc Aneurysm growth occurs at region of low wall shear stress: patient-specific correlation of hemodynamics and growth in a longitudinal study
    Loic Boussel
    Department of Radiology, VA Medical Center, San Francisco, USA 94121, USA
    Stroke 39:2997-3002. 2008
    ..Low wall shear stress (WSS) has been reported to have a negative effect on endothelial cells normal physiology and may be an important contributor to local remodeling of the arterial wall and to aneurysm growth and rupture...
  7. ncbi Characterizing of tissue microstructure with single-detector polarization-sensitive optical coherence tomography
    Bin Liu
    Department of Orthopedic Surgery, Brigham and Women s Hospital, Massachusetts, USA
    Appl Opt 45:4464-79. 2006
    ..This study, along with the data in part I, advance the insights gained from PS-OCT images beyond simply determining the presence or absence of birefringence...
  8. ncbi New techniques for imaging, digitization and analysis of three-dimensional neural morphology on multiple scales
    S L Wearne
    Computational Neurobiology and Imaging Center, Mount Sinai School of Medicine, New York, NY 10029 6574, USA
    Neuroscience 136:661-80. 2005
    ....
  9. pmc Discriminating power of localized three-dimensional facial morphology
    Peter Hammond
    Eastman Dental Institute, University College London, London, WC1X 8LD, United Kingdom
    Am J Hum Genet 77:999-1010. 2005
    ....
  10. ncbi Effect of endothelial shear stress on the progression of coronary artery disease, vascular remodeling, and in-stent restenosis in humans: in vivo 6-month follow-up study
    Peter H Stone
    Cardiovascular Division, Brigham and Women s Hospital, 75 Francis St, Boston, Mass 02115, USA
    Circulation 108:438-44. 2003
    ..The endothelium controls local arterial responses by transduction of shear stress. Characterization of endothelial shear stress (ESS) may allow for prediction of progression of atherosclerosis and in-stent restenosis...
  11. ncbi Texture analysis of medical images
    G Castellano
    Neuroimage Laboratory, Faculty of Medical Sciences, State University of Campinas, Brazil
    Clin Radiol 59:1061-9. 2004
    ..In this article we clarify the principles of texture analysis and give examples of its applications, reviewing studies of the technique...
  12. pmc The Mouse Limb Anatomy Atlas: an interactive 3D tool for studying embryonic limb patterning
    April DeLaurier
    Division of Developmental Biology, National Institute for Medical Research, The Ridgeway, Mill Hill, London, UK
    BMC Dev Biol 8:83. 2008
    ..Existing textual references consist of two-dimensional (2D) illustrations of the adult rat or mouse limb that can be difficult to apply when attempting to describe the complex three-dimensional (3D) relationship between tissues...
  13. ncbi Anatomically constrained region deformation for the automated segmentation of the hippocampus and the amygdala: Method and validation on controls and patients with Alzheimer's disease
    Marie Chupin
    Department of Clinical and Experimental Epilepsy, Institute of Neurology, UCL, UK
    Neuroimage 34:996-1019. 2007
    ..The proposed approach provides a new framework for further developments in quantitative analyses of the pathological hippocampus and amygdala in MRI scans...
  14. ncbi The molecular architecture of axonemes revealed by cryoelectron tomography
    Daniela Nicastro
    Laboratory for 3D Electron Microscopy of Cells, Department of Molecular, Cellular, and Developmental Biology, CB 347, University of Colorado, Boulder, CO 80309 0347, USA
    Science 313:944-8. 2006
    ..Periodic densities were also observed inside doublet microtubules; these may contribute to doublet stability...
  15. doi Accuracy of three-dimensional measurements obtained from cone beam computed tomography surface-rendered images for cephalometric analysis: influence of patient scanning position
    Bassam Hassan
    Department of Oral Radiology, Academic Centre for Dentistry Amsterdam ACTA, The Netherlands
    Eur J Orthod 31:129-34. 2009
    ..The findings indicate that measurements based on 3D CBCT surface images are accurate and that small variations in the patient's head position do not influence measurement accuracy...
  16. pmc High-throughput morphologic phenotyping of the mouse brain with magnetic resonance histology
    G Allan Johnson
    Center for In Vivo Microscopy, Box 3302, Duke University Medical Center, Durham, NC 27710, USA
    Neuroimage 37:82-9. 2007
    ..These collection and acquisition methods are now available to the neuroscience community as a standard web-deliverable service...
  17. pmc Visualizing and clustering high throughput sub-cellular localization imaging
    Nicholas A Hamilton
    ARC Centre of Excellence in Bioinformatics, The University of Queensland, Brisbane, Queensland 4072, Australia
    BMC Bioinformatics 9:81. 2008
    ..The result is images that are statistically similar are spatially close in the visualization allowing for easy comparison of images that are similar and distinguishment of dissimilar images into distinct clusters...
  18. ncbi Tumor volume in pharyngolaryngeal squamous cell carcinoma: comparison at CT, MR imaging, and FDG PET and validation with surgical specimen
    Jean François Daisne
    Head and Neck Oncology Program, St Luc University Hospital, Universite Catholique de Louvain, 10 Ave Hippocrate, 1200 Brussels, Belgium
    Radiology 233:93-100. 2004
    ....
  19. pmc Multicell simulations of development and disease using the CompuCell3D simulation environment
    Maciej H Swat
    Biocomplexity Institute and Department of Physics, Indiana University, Bloomington, USA
    Methods Mol Biol 500:361-428. 2009
    ..This tutorial introduces Glazier-Graner-Hogeweg (GGH) multicell simulations and CompuCell3D, a simulation framework that allows users to build, test, and run GGH simulations...
  20. ncbi Tomographic molecular imaging and 3D quantification within adult mouse organs
    Tomas Alanentalo
    Umeå Center for Molecular Medicine, Umea University, S 901 87, Umea, Sweden
    Nat Methods 4:31-3. 2007
    ..Using the nonobese diabetic (NOD) mouse model, we demonstrate a correlation between total islet beta-cell volume and the onset of type-1 diabetes...
  21. pmc Direct three-dimensional myocardial strain tensor quantification and tracking using zHARP
    Khaled Z Abd-Elmoniem
    Department of Radiology and Radiological Sciences, School of Medicine, Johns Hopkins University, Baltimore, MD 21287, USA
    Med Image Anal 12:778-86. 2008
    ..The performance and accuracy of the method is demonstrated in vitro on a phantom and in vivo in four healthy adult human subjects...
  22. ncbi Ultrahigh-resolution full-field optical coherence tomography
    Arnaud Dubois
    Laboratoire d Optique Physique, Ecole Superieure de Physique et Chimie Industrielles, Centre National de la Recherche Scientifique, Unité Propre de Recherche A0005, 10 rue Vauquelin, F 75231 Paris Cedex 5, France
    Appl Opt 43:2874-83. 2004
    ..A shot-noise-limited detection sensitivity of 90 dB is obtained in an acquisition time per image of 4 s. Subcellular-level images of plant, animal, and human tissues are presented...
  23. ncbi Rigid registration of 3-D ultrasound with MR images: a new approach combining intensity and gradient information
    A Roche
    INRIA Projet Epidaure, Sophia Antipolis, France
    IEEE Trans Med Imaging 20:1038-49. 2001
    ..A cross-validation study has been carried out using a number of phantom and clinical data. This indicates that the method is quite robust and that the worst registration errors are of the order of the MR image resolution...
  24. pmc Nodavirus coat protein imposes dodecahedral RNA structure independent of nucleotide sequence and length
    Mariana Tihova
    Department of Cell Biology, The Scripps Research Institute, Scripps Clinic, La Jolla, California 92037, USA
    J Virol 78:2897-905. 2004
    ..We propose that the capsid protein is able to exploit the plasticity of the RNA secondary structures, capturing those that are compatible with the geometry of the dodecahedral cage...
  25. ncbi Regional deficits in brain volume in schizophrenia: a meta-analysis of voxel-based morphometry studies
    Robyn Honea
    Prince of Wales International Centre for SANE Research, Department of Psychiatry, University of Oxford, Warneford Hospital, Headington, Oxford, UK OX3 7JX
    Am J Psychiatry 162:2233-45. 2005
    ....
  26. ncbi New magnetic resonance imaging-based method for defining the extent of left atrial wall injury after the ablation of atrial fibrillation
    Christopher J McGann
    Radiology Department, University of Utah School of Medicine, University of Utah, Salt Lake City, Utah, USA
    J Am Coll Cardiol 52:1263-71. 2008
    ..Using a 3-dimensional (3D) delayed-enhancement magnetic resonance imaging (MRI) sequence and novel processing methods, LA wall scarring is visualized at high resolution after radiofrequency ablation (RFA)...
  27. ncbi Recommendations from Gynaecological (GYN) GEC-ESTRO Working Group (I): concepts and terms in 3D image based 3D treatment planning in cervix cancer brachytherapy with emphasis on MRI assessment of GTV and CTV
    Christine Haie-Meder
    Department of Radiotherapy, Brachytherapy Unit, Institut Gustave Roussy, 39 rue Camille Desmoulins, 94805 Villejuif, France
    Radiother Oncol 74:235-45. 2005
    ..When introducing a 3D image based approach for GTV and CTV assessment, there is a need for a common language to describe the concepts and to define the terms which are to be used...
  28. ncbi Measurement of myocardial mechanics in mice before and after infarction using multislice displacement-encoded MRI with 3D motion encoding
    Wesley D Gilson
    Department of Biomedical Engineering, University of Virginia, Charlottesville, Virginia 22908, USA
    Am J Physiol Heart Circ Physiol 288:H1491-7. 2005
    ..07 +/- 0.54 degrees /mm (R = 0.96, P < 0.05). DENSE MRI can assess the 3D myocardial mechanics of the murine heart in <1 h of scan time at 4.7 T and may be applied to studies of myocardial mechanics in genetically engineered mice...
  29. ncbi Magnitude and role of wall shear stress on cerebral aneurysm: computational fluid dynamic study of 20 middle cerebral artery aneurysms
    Masaaki Shojima
    Department of Neurosurgery, Faculty of Medicine, University of Tokyo, Japan
    Stroke 35:2500-5. 2004
    ..The magnitude and distribution of the WSS in and around human middle cerebral artery (MCA) aneurysms were analyzed using the method of computed fluid dynamics (CFD)...
  30. ncbi Image-based computational fluid dynamics modeling in realistic arterial geometries
    David A Steinman
    Imaging Research Laboratories, The John P Robarts Research Institute, The University of Western Ontario, London, Canada
    Ann Biomed Eng 30:483-97. 2002
    ..Issues related to accuracy, precision, and modeling assumptions are also discussed...
  31. ncbi False discovery rate revisited: FDR and topological inference using Gaussian random fields
    Justin R Chumbley
    Wellcome Trust Centre for Neuroimaging, University College London, London, UK
    Neuroimage 44:62-70. 2009
    ..We describe the nature of the problem, illustrate it with some examples and suggest a simple solution based on controlling the false discovery rate of connected excursion sets within an SPM, characterised by their volume...
  32. pmc Detection and quantification of left atrial structural remodeling with delayed-enhancement magnetic resonance imaging in patients with atrial fibrillation
    Robert S Oakes
    Atrial Fibrillation Program, University of Utah School of Medicine, Salt Lake City, UT 84132 2400, USA
    Circulation 119:1758-67. 2009
    ..In this study, we report the utility of delayed-enhancement magnetic resonance imaging (DE-MRI) in detecting abnormal atrial tissue before radiofrequency ablation and in predicting procedural outcome...
  33. ncbi Global brain atrophy and corticospinal tract alterations in ALS, as investigated by voxel-based morphometry of 3-D MRI
    Jan Kassubek
    Department of Neurology, University of Ulm, Germany
    Amyotroph Lateral Scler Other Motor Neuron Disord 6:213-20. 2005
    ..VBM might be a potential tool to visualize disease progression in future longitudinal studies...
  34. ncbi Time-resolved contrast-enhanced three-dimensional magnetic resonance angiography of the chest: combination of parallel imaging with view sharing (TREAT)
    Christian Fink
    Abteilung Radiologie, Deutsches Krebsforschungszentrum DKFZ, Innovative Krebsdiagnostik und Therapie, Heidelberg, Germany
    Invest Radiol 40:40-8. 2005
    ....
  35. ncbi Validity and reliability of craniofacial anthropometric measurement of 3D digital photogrammetric images
    Julielynn Y Wong
    Craniofacial Centre, Division of Plastic Surgery, Children s Hospital, Harvard Medical School, Boston, MA, USA
    Cleft Palate Craniofac J 45:232-9. 2008
    ..Before morphometry using digital photogrammetry can be applied in clinical and research practice, it must be assessed against direct anthropometry...
  36. doi What is cone-beam CT and how does it work?
    William C Scarfe
    Department of Surgical Hospital Dentistry, University of Louisville School of Dentistry, 501 South Preston Street, Louisville, KY 40292, USA
    Dent Clin North Am 52:707-30, v. 2008
    ..Future enhancements most likely will be directed toward reducing scan time; providing multimodal imaging; improving image fidelity, including soft tissue contrast; and incorporating task-specific protocols to minimize patient dose...
  37. ncbi Evaluation of lung volumetry using dynamic three-dimensional magnetic resonance imaging
    Christian Plathow
    Department of Radiology, German Cancer Research Center, Heidelberg, Germany
    Invest Radiol 40:173-9. 2005
    ..We sought to investigate lung volume and surface measurements during the breathing cycle using dynamic three-dimensional magnetic resonance imaging (3D MRI)...
  38. ncbi 3D analysis of facial morphology
    Peter Hammond
    Eastman Dental Institute, UCL, London, United Kingdom
    Am J Med Genet A 126:339-48. 2004
    ..This article contains supplementary material, which may be viewed at the American Journal of Medical Genetics website at http://www.interscience.wiley.com/jpages/0148-7299/suppmat/index.html...
  39. ncbi Quantitative comparison of algorithms for inter-subject registration of 3D volumetric brain MRI scans
    Babak A Ardekani
    Center for Advanced Brain Imaging, Nathan Kline Institute for Psychiatric Research, 140 Old Orangeburg Road, Orangeburg, NY 10962, USA
    J Neurosci Methods 142:67-76. 2005
    ..The spatial dispersion measure was found to be more sensitive when the landmarks were placed after image registration. The standard deviation measure was found sensitive to intensity normalization or the method of image interpolation...
  40. ncbi A new technique for the creation of a computerized composite skull model
    Jaime Gateno
    Department of Oral and Maxillofacial Surgery, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA
    J Oral Maxillofac Surg 61:222-7. 2003
    ..The computerized composite skull model is the combination of a 3-dimensional (3D) computed tomography (CT) bone model with digital dental models...
  41. ncbi Accelerating molecular modeling applications with graphics processors
    JOHN E STONE
    Beckman Institute, University of Illinois at Urbana Champaign, Urbana, IL 61801, USA
    J Comput Chem 28:2618-40. 2007
    ..In light of the performance obtained for this set of calculations, future applications of graphics processors to molecular dynamics simulations are discussed...
  42. ncbi Atlas renormalization for improved brain MR image segmentation across scanner platforms
    Xiao Han
    Athinoula A Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA
    IEEE Trans Med Imaging 26:479-86. 2007
    ....
  43. ncbi Fluid-structure interaction within realistic three-dimensional models of the aneurysmatic aorta as a guidance to assess the risk of rupture of the aneurysm
    E S Di Martino
    Department of Bioengineering, Politecnico of Milano, Milan, Italy
    Med Eng Phys 23:647-55. 2001
    ..A proven clinical efficacy may promote the method as a tool to determine factual aneurysm risk of rupture and aid the surgeon to refer elective surgery patients...
  44. ncbi The use of a new 3D splint and double CT scan procedure to obtain an accurate anatomic virtual augmented model of the skull
    G R J Swennen
    Division of Maxillo Facial Surgery, Department of Surgery, General Hospital St Jan Bruges, Rudershove 10, 8000 Bruges, Belgium
    Int J Oral Maxillofac Surg 36:146-52. 2007
    ..0491-0.0622). The combination of the newly designed 3D splint with the double CT scan procedure allowed accurate registration and the set-up of an accurate anatomic 3D virtual augmented model of the skull with detailed dental surface...
  45. pmc Sources and effects of electrode impedance during deep brain stimulation
    Christopher R Butson
    Department of Biomedical Engineering, Cleveland Clinic Foundation, 9500 Euclid Ave ND 20, Cleveland, OH 44195, USA
    Clin Neurophysiol 117:447-54. 2006
    ....
  46. pmc Second-harmonic imaging microscopy of normal human and keratoconus cornea
    Naoyuki Morishige
    The Eye Institute, School of Medicine, University of California Irvine Medical Center, Orange, California
    Invest Ophthalmol Vis Sci 48:1087-94. 2007
    ..The purpose of this study was to evaluate the ability of second-harmonic imaging to identify differences in corneal stromal collagen organization between normal human and keratoconus corneas...
  47. ncbi 3D MRI-based multicomponent FSI models for atherosclerotic plaques
    Dalin Tang
    Mathematical Sciences Department, Worcester Polytechnic Institute, Worcester, MA 01609, USA
    Ann Biomed Eng 32:947-60. 2004
    ..Large-scale patient studies are needed to validate the computational findings for possible plaque vulnerability assessment and rupture predictions...
  48. ncbi Automatic segmentation of cortical and trabecular compartments based on a dual threshold technique for in vivo micro-CT bone analysis
    Helen R Buie
    Department of Mechanical and Manufacturing Engineering, Schulich School of Engineering, University of Calgary, 2500 University Drive N W, Calgary, Alberta, Canada T2N 1N4
    Bone 41:505-15. 2007
    ..Using the same input thresholds for similar datasets assures maximal consistency while alleviating time consuming semi-automated contouring...
  49. ncbi A layer-specific three-dimensional model for the simulation of balloon angioplasty using magnetic resonance imaging and mechanical testing
    Gerhard A Holzapfel
    Institute for Structural Analysis Computational Biomechanics, Graz University of Technology, Austria
    Ann Biomed Eng 30:753-67. 2002
    ....
  50. pmc Globally optimal stitching of tiled 3D microscopic image acquisitions
    Stephan Preibisch
    Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany
    Bioinformatics 25:1463-5. 2009
    ..The physical coordinates provided by the microscope stage are not precise enough to allow direct reconstruction (Stitching) of the whole image from individual image stacks...
  51. ncbi Whole-heart steady-state free precession coronary artery magnetic resonance angiography
    Oliver M Weber
    Department of Radiology, University of California San Francisco, San Francisco, California 94143, USA
    Magn Reson Med 50:1223-8. 2003
    ..It is concluded that the whole-heart coronary MRA technique improves visible vessel length and facilitates high-quality coronary MRA of the complete coronary artery tree in a single measurement...
  52. ncbi Hippocampal head size associated with verbal memory performance in nondemented elderly
    V H Hackert
    Department of Epidemiology and Biostatistics, Erasmus Medical Center, Rotterdam, The Netherlands
    Neuroimage 17:1365-72. 2002
    ..06, 0.59)). Our data suggest selective involvement of the hippocampal head in verbal memory, and add to recent findings of functional segregation along the longitudinal axis of the hippocampus...
  53. ncbi Estimating linear cortical magnification in human primary visual cortex via dynamic programming
    Anqi Qiu
    Center for Imaging Science, Johns Hopkins University, Baltimore, MD 21218, USA
    Neuroimage 31:125-38. 2006
    ..The reliability of these estimates was assessed by comparing results based on data from one quadrant to those based on data from the full hemifield along with a split-half reliability analysis...
  54. ncbi A novel method for the 3-dimensional simulation of orthognathic surgery by using a multimodal image-fusion technique
    Jun Uechi
    Department of Orthodontics, School of Dentistry, Health Sciences University of Hokkaido, Ishikari Tobetsu, Japan
    Am J Orthod Dentofacial Orthop 130:786-98. 2006
    ..The aim of this study was to establish a novel method for simulating orthognathic surgery in 3-dimensional (3D) space...
  55. ncbi Methods of assessment of cleft-related facial deformity: a review
    I Al-Omari
    University of Jordan Dental School, Amman, Jordan
    Cleft Palate Craniofac J 42:145-56. 2005
    ..To review the stimulus media, measurements and scoring system, rater's characteristics, and facial region used in assessment of the appearance of cleft-related deformity...
  56. doi Completing the 3-dimensional picture
    Christopher Lane
    Am J Orthod Dentofacial Orthop 133:612-20. 2008
    ..These 3D systems enable extraoral imaging protocols to be equally precise in providing highly accurate 3D facial surface images for diagnosis, analysis, treatment monitoring, simulation, and outcome evaluation...
  57. ncbi Sex-based differences in the anthropometric characteristics of the anterior cruciate ligament and its relation to intercondylar notch geometry: a cadaveric study
    Naveen Chandrashekar
    Mechanical Engineering Department, Texas Tech University, Lubbock, TX 79409, USA
    Am J Sports Med 33:1492-8. 2005
    ..Reasons for this disparity are not well understood; however, sex-based differences in the geometry of the anterior cruciate ligament, its morphologic characteristics, and the intercondylar notch size have been cited as possible factors...
  58. ncbi Fast high-resolution T1 mapping of the human brain
    Ralf Deichmann
    Wellcome Department of Imaging Neuroscience, Institute of Neurology, London, UK
    Magn Reson Med 54:20-7. 2005
    ..In addition, an improved fitting algorithm based on smoothed flip angle maps is presented and tested successfully...
  59. pmc Myocardial 3D strain calculation by combining cine displacement encoding with stimulated echoes (DENSE) and cine strain encoding (SENC) imaging
    Aaron T Hess
    Department of Human Biology, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa
    Magn Reson Med 62:77-84. 2009
    ..42 +/-0.11, -0.10 +/-0.03, and -0.21 +/-0.02, respectively. These results show that this technique is capable of reliably quantifying 3D cardiac strain...
  60. pmc 3D structure of eukaryotic flagella in a quiescent state revealed by cryo-electron tomography
    Daniela Nicastro
    Abteilung Molekulare Strukturbiologie, Max Planck Institut fur Biochemie, 82152 Martinsried, Germany
    Proc Natl Acad Sci U S A 102:15889-94. 2005
    ..Cryo-electron tomography has proven to be a powerful technique for helping us understand the relationships between flagellar structure and function and the design of macromolecular machines in situ...
  61. ncbi Assessment of bone segmentation quality of cone-beam CT versus multislice spiral CT: a pilot study
    Miet Loubele
    Medical Image Computing ESAT Radiology, Faculties of Engineering and Medicine, K U Leuven, Leuven, Belgium
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 102:225-34. 2006
    ..The objective of this study was to quantitatively assess the quality of jawbone models generated from cone beam computed tomography (CBCT) by comparison with similar models obtained from multislice spiral computed tomography (MSCT)...
  62. ncbi Rapid automated three-dimensional tracing of neurons from confocal image stacks
    Khalid A Al-Kofahi
    Electrical, Computer, and Systems Engineering Department, Rensselaer Polytechnic Institute, Troy, NY 12180 3590, USA
    IEEE Trans Inf Technol Biomed 6:171-87. 2002
    ..These properties make it attractive for large-scale automated tissue studies that require rapid on-line image analysis, such as high-throughput neurobiology/angiogenesis assays, and initiatives such as the Human Brain Project...
  63. ncbi Accuracy of CT-based thickness measurement of thin structures: modeling of limited spatial resolution in all three dimensions
    Sven Prevrhal
    Osteoporosis and Arthritis Research Group, Department of Radiology, University of California San Francisco, San Francisco, California 94117, USA
    Med Phys 30:1-8. 2003
    ....
  64. pmc 3D micro-CT imaging of the postmortem brain
    Alex de Crespigny
    Athinoula A Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, MA 02129, USA
    J Neurosci Methods 171:207-13. 2008
    ..For simple measurements, such as tumor volume and non-destructive postmortem brain screening, microCT may prove to be a valuable alternative to standard histopathology or microMRI...
  65. doi Inter- and intraobserver variation in HR-CTV contouring: intercomparison of transverse and paratransverse image orientation in 3D-MRI assisted cervix cancer brachytherapy
    Primoz Petric
    Department of Radiotherapy and Radiobiology, Medical University of Vienna, Vienna, Austria
    Radiother Oncol 89:164-71. 2008
    ..To analyze agreement between target volumes, delineated by two observers on transverse (T) and paratransverse (perpendicular to the long cervical axis - PT) MR images for cervix cancer brachytherapy...
  66. ncbi Evaluation of reproducibility and reliability of 3D soft tissue analysis using 3D stereophotogrammetry
    J M Plooij
    3D Facial Imaging Research Group Nijmegen Bruges 3D FIRG, Department of Oral and Maxillofacial Surgery, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Int J Oral Maxillofac Surg 38:267-73. 2009
    ..This shows that hard tissue data are not needed to perform accurate soft tissue analysis...
  67. ncbi An Eulerian PDE approach for computing tissue thickness
    Anthony J Yezzi
    School of Electrical and Computer Engineering, Georgia Institute of Technology, Atlanta, GA 30322, USA
    IEEE Trans Med Imaging 22:1332-9. 2003
    ..These experiments reveal very good performance and show strong potential for application in tissue thickness visualization and quantification...
  68. ncbi Morphogenesis and oncogenesis of MCF-10A mammary epithelial acini grown in three-dimensional basement membrane cultures
    Jayanta Debnath
    Department of Cell Biology, Harvard Medical School, 240 Longwood Avenue, Boston, MA 02115, USA
    Methods 30:256-68. 2003
    ....
  69. doi Wall shear stress on ruptured and unruptured intracranial aneurysms at the internal carotid artery
    L D Jou
    Department of Radiology, Baylor College of Medicine, Houston, TX 77030, USA
    AJNR Am J Neuroradiol 29:1761-7. 2008
    ..Flow impingement, greater pressure, and abnormal wall shear stress are all indications for aneurysm rupture. Characterizing wall shear stress for intracranial aneurysms at similar anatomic locations may help in understanding its role...
  70. ncbi Usefulness of three-dimensional, multidetector row CT (virtual gastroscopy and multiplanar reconstruction) in the evaluation of gastric cancer: a comparison with conventional endoscopy, EUS, and histopathology
    Suryaprakash Bhandari
    Institute for Digestive Research and Department of Radiology, Soon Chun Hyang University College of Medicine, Seoul, South Korea
    Gastrointest Endosc 59:619-26. 2004
    ..The aim of this study was to assess the role of three-dimensional multidetector row CT for detection, precise localization, and staging of gastric cancer by comparison with conventional endoscopy, EUS, and histopathology...
  71. ncbi Three-dimensional coronary MR angiography performed with subject-specific cardiac acquisition windows and motion-adapted respiratory gating
    Sven Plein
    British Heart Foundation Cardiac MRI Unit, Rm 170, D Fl, Jubilee Building, Leeds General Infirmary, Great George Street, Leeds LS1 3EX, United Kingdom
    AJR Am J Roentgenol 180:505-12. 2003
    ..We hypothesized that a more flexible and subject-specific approach to cardiac and respiratory gating may shorten scanning times while maintaining image quality...
  72. ncbi Two-photon 3-D mapping of ex vivo human skin endogenous fluorescence species based on fluorescence emission spectra
    Lily H Laiho
    Massachusetts Institute of Technology, Department of Mechanical Engineering, 77 Massachusetts Avenue, NE47 276, Cambridge, Massachusetts 02139, USA
    J Biomed Opt 10:024016. 2005
    ..Luminescence species identified include tryptophan, NAD(P)H, melanin, and elastin, which are autofluorescent, and collagen that contributes to a second harmonic signal...
  73. ncbi Gastric cancer: preoperative local staging with 3D multi-detector row CT--correlation with surgical and histopathologic results
    Chiao Yun Chen
    Department of Medical Imaging, Kaohsiung Medical University, Chung Ho Memorial Hospital, 100 Tz You 1st Road, Kaohsiung, Taiwan
    Radiology 242:472-82. 2007
    ..To prospectively evaluate accuracy of multi-detector row computed tomographic (CT) images for preoperative staging of gastric cancer by using surgical and histopathologic results as reference standards...
  74. pmc The three-dimensional micro- and nanostructure of the aortic medial lamellar unit measured using 3D confocal and electron microscopy imaging
    Mary K O'Connell
    Department of Mechanical Engineering, Stanford University, Stanford, CA, USA
    Matrix Biol 27:171-81. 2008
    ..This high resolution three-dimensional view of the aortic media reveals MLU microstructure details that suggest a highly complex and integrated mural organization that correlates with aortic mechanical properties...
  75. pmc Three-dimensional cone-beam computed tomography for assessment of mandibular changes after orthognathic surgery
    Lucia H S Cevidanes
    Department of Orthodontics, School of Dentistry, University of North Carolina, Chapel Hill, NC 27599 7450, USA
    Am J Orthod Dentofacial Orthop 131:44-50. 2007
    ..The purpose of this study was to assess alterations in the 3-dimensional (3D) position of the mandibular rami and condyles in patients receiving either maxillary advancement and mandibular setback or maxillary surgery only...
  76. ncbi New methods of MR image intensity standardization via generalized scale
    Anant Madabhushi
    Department of Biomedical Engineering, Rutgers The State University of New Jersey, 617 Bowser Road, Room 101, Piscataway, New Jersey 08854, USA
    Med Phys 33:3426-34. 2006
    ..The new scale-based methods were found to be better than the existing methods, with a significant improvement observed for severely diseased and abnormal patient studies...
  77. ncbi Analysis of barley (Hordeum vulgare) grain development using three-dimensional digital models
    Sabine Gubatz
    Leibniz Institute of Plant Genetics and Crop Plant Research IPK, Corrensstr 3, D 06466, Gatersleben, Germany
    Plant J 52:779-90. 2007
    ..At anthesis, mRNA of the protease nucellin was visualized in a distinct zone of the nucellus near the antipodal cells...
  78. ncbi Airflow limitation and airway dimensions in chronic obstructive pulmonary disease
    Masaru Hasegawa
    First Department of Medicine, Hokkaido University School of Medicine, N 15 W 7 Kita ku, Sapporo 060 8638, Japan
    Am J Respir Crit Care Med 173:1309-15. 2006
    ..Computed tomography has been widely used to assess emphysema severity, but less attention has been paid to the assessment of airway disease using computed tomography...
  79. ncbi Polyp detection with CT colonography: primary 3D endoluminal analysis versus primary 2D transverse analysis with computer-assisted reader software
    Stuart A Taylor
    Department of Intestinal Imaging, St Mark s Hospital, Northwick Park, Harrow, United Kingdom
    Radiology 239:759-67. 2006
    ....
  80. ncbi Detecting molecular interactions that stabilize native bovine rhodopsin
    K Tanuj Sapra
    Center for Biotechnology, University of Technology, 01307 Dresden, Germany
    J Mol Biol 358:255-69. 2006
    ..These changes highlight the structural importance of this disulfide bond and may form the basis of dysfunctions associated with its absence...
  81. pmc Three-dimensional endomicroscopy of the human colon using optical coherence tomography
    Desmond C Adler
    Department of Electrical Engineering and Computer Science, and Research Laboratory of Electronics, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA
    Opt Express 17:784-96. 2009
    ..This clinical pilot study demonstrates the potential of 3D-OCT for distinguishing normal from pathologic colorectal tissue, assessing endoscopic therapies and healing progression...
  82. ncbi Fast isotropic volumetric coronary MR angiography using free-breathing 3D radial balanced FFE acquisition
    C Stehning
    Institute of Biomedical Engineering IBT, Karlsruhe, Germany
    Magn Reson Med 52:197-203. 2004
    ..The scan time ranged from 10 to 14 min during free breathing at a heart rate of 60 bpm, which is comparable to that of a thin-slab protocol comprising multiple scans for each coronary artery...
  83. ncbi The interobserver reliability and validity of volume calculation from three-dimensional ultrasound datasets in the in vitro setting
    N J Raine-Fenning
    School of Human Development, Academic Division of Reproductive Medicine, Queens Medical Centre, Nottingham, UK
    Ultrasound Obstet Gynecol 21:283-91. 2003
    ....
  84. ncbi Can PET provide the 3D extent of tumor motion for individualized internal target volumes? A phantom study of the limitations of CT and the promise of PET
    Curtis B Caldwell
    Sunnybrook and Women s College Health Sciences Centre, Toronto, Ontario, Canada
    Int J Radiat Oncol Biol Phys 55:1381-93. 2003
    ....
  85. ncbi Multiplanar and three-dimensional multi-detector row CT of thoracic vessels and airways in the pediatric population
    Marilyn J Siegel
    Edward Mallinckrodt Institute of Radiology, Washington University School of Medicine, 510 S Kingshighway Blvd, St Louis, MO 63110, USA
    Radiology 229:641-50. 2003
    ....
  86. pmc A study of diffusion tensor imaging by tissue-specific, smoothing-compensated voxel-based analysis
    Jee Eun Lee
    Waisman Laboratory for Brain Imaging and Behavior, Waisman Center, Madison, WI 53705, USA
    Neuroimage 44:870-83. 2009
    ..The T-SPOON method may be also applicable to other quantitative imaging maps such as T1 or T2 relaxometry, magnetization transfer, or PET tracer maps...
  87. ncbi Serial registration of intraoperative MR images of the brain
    Matthieu Ferrant
    Communications and Remote Sensing Laboratory, Universite Catholique de Louvain, B 1348, Louvain la Neuve, Belgium
    Med Image Anal 6:337-59. 2002
    ..7+/-0.6 mm (mean+/-S.D.) for boundary surface landmarks, of 0.9+/-0.6 mm for landmarks inside the boundary surfaces, and 1.6+/-0.9 mm for landmarks in the vicinity of the tumor...
  88. ncbi eF-site and PDBjViewer: database and viewer for protein functional sites
    Kengo Kinoshita
    Graduate School of Integrated Science, Yokohama City University, 1 7 29 Suehiro cho, Tsurumi ku, Yokohama, 230 0045, Japan
    Bioinformatics 20:1329-30. 2004
    ..To enable browsing of each molecular surface along with the atomic model, we have developed a new three-dimensional interactive viewer, PDBjViewer, that can be used both as an applet and as a stand-alone program...
  89. ncbi Registration of 3-D intraoperative MR images of the brain using a finite-element biomechanical model
    M Ferrant
    Communications and Remote Sensing Laboratory, Universite Catholique de Louvain, Louvain la Neuve, Belgium
    IEEE Trans Med Imaging 20:1384-97. 2001
    ..Cortical surface shifts of up to 10 mm and subsurface shifts of up to 6 mm were recovered with an accuracy of 1 mm or less and 3 mm or less respectively...
  90. ncbi Mutual-information-based registration of medical images: a survey
    Josien P W Pluim
    University Medical Center Utrecht, Image Sciences Institute, Room E01 335, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands
    IEEE Trans Med Imaging 22:986-1004. 2003
    ..Comparison studies including mutual information are also considered. The paper starts with a description of entropy and mutual information and it closes with a discussion on past achievements and some future challenges...
  91. ncbi Visualization of flow patterns distal to aortic valve prostheses in humans using a fast approach for cine 3D velocity mapping
    S Kozerke
    Institute of Biomedical Engineering, University of Zurich and Swiss Federal Institute of Technology, Switzerland
    J Magn Reson Imaging 13:690-8. 2001
    ..It is concluded that MR velocity mapping is a potential tool for studying 3D flow patterns evolving around heart valve prostheses in humans. J. Magn. Reson. Imaging 2001;13:690-698...
  92. ncbi The impact of contouring uncertainty on rectal 3D dose-volume data: results of a dummy run in a multicenter trial (AIROPROS01-02)
    Franca Foppiano
    Department of Medical Physics, National Cancer Research Institute, Genova, Italy
    Int J Radiat Oncol Biol Phys 57:573-9. 2003
    ..To estimate the impact of the uncertainty in contouring the rectum on rectal dose-volume parameters and normal tissue complication probability (NTCP) in a prospective (AIROPROS01-02) investigation about rectal toxicity...
  93. ncbi Value of three-dimensional US for optimizing guidance for ablating focal liver tumors
    S C Rose
    Department of Radiology, University of California Medical Center, 200 West Arbor Drive, San Diego, CA 92103, USA
    J Vasc Interv Radiol 12:507-15. 2001
    ....
  94. ncbi Nonrigid registration of 3D tensor medical data
    J Ruiz-Alzola
    Medical Technology Center, University of Las Palmas de Gran Canaria and Gran Canaria Dr Negrín Hospital, Spain
    Med Image Anal 6:143-61. 2002
    ..The feasibility of the approach is illustrated by results on synthetic and clinical data...
  95. ncbi Navigator-gated coronary magnetic resonance angiography using steady-state-free-precession: comparison to standard T2-prepared gradient-echo and spiral imaging
    Elmar Spuentrup
    Department of Diagnostic Radiology, Technical University of Aachen, Aachen, Germany
    Invest Radiol 38:263-8. 2003
    ..The purpose of this study was a systematic comparison of SSFP cMRA with standard T2-prepared gradient-echo and spiral cMRA...
  96. ncbi Three-dimensional adaptive filtering in magnetic resonance angiography
    C F Westin
    Surgical Planning Laboratory, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA
    J Magn Reson Imaging 14:63-71. 2001
    ..9 dB) were observed. 3D adaptive filtering may provide an alternative to prolonging the scan time or using contrast agents in MRA when the CNR is low...
  97. ncbi Navigator-gated free-breathing three-dimensional balanced fast field echo (TrueFISP) coronary magnetic resonance angiography
    Elmar Spuentrup
    Department of Medicine Cardiovascular Division, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts, USA
    Invest Radiol 37:637-42. 2002
    ..It is hypothesized that Balanced-FFE may be valuable for contrast enhancement in 3D free-breathing coronary MRA...
  98. ncbi Improved visualization of coronary arteries using a new three-dimensional submillimeter MR coronary angiography sequence with balanced gradients
    Benedetta Giorgi
    Department of Radiology, Gasthuisberg University Hospital, Catholic University of Leuven, Herestraat 49, B 3000 Leuven, Belgium
    AJR Am J Roentgenol 179:901-10. 2002
    ..The goal of our study was to evaluate a new three-dimensional real-time navigator MR coronary angiography sequence to noninvasively visualize the coronary arteries...
  99. ncbi Effects of noise, image resolution, and ROI definition on the accuracy of standard uptake values: a simulation study
    Ronald Boellaard
    PET Center, VU University Medical Center, Amsterdam, The Netherlands
    J Nucl Med 45:1519-27. 2004
    ..Therefore, an experimental and simulation study was performed to determine the effects of noise, image resolution, and region-of-interest (ROI) definition on the accuracy of SUVs...
  100. ncbi Biphasic tissue Doppler waveforms during isovolumic phases are associated with asynchronous deformation of subendocardial and subepicardial layers
    Partho P Sengupta
    Division of Cardiovascular Diseases, Mayo Clinic Rochester, 200 First St SW, Rochester, MN 55905, USA
    J Appl Physiol 99:1104-11. 2005
    ..The results support an association between asynchronous deformation of subendocardial and subepicardial muscle fibers and the biphasic isovolumic movements observed with high-resolution tissue Doppler imaging...
  101. ncbi Accuracy of finite element model-based multi-organ deformable image registration
    K K Brock
    Radiation Medicine Program, Princess Margaret Hospital, University Health Network, 610 University Avenue, Toronto, Ontario, Canada M5G 2M9
    Med Phys 32:1647-59. 2005
    ....

Research Grants83

  1. Office based Real-time high Speed 3-D OCT system for Diagnosis of EarlyLaryngeal
    TIRUNELVELI RAMALINGAM; Fiscal Year: 2010
    ..Out technology which was developed in the laboratory is now being transferred to market place through OCTMI. Hence this proposal in ideal for PA-08-114 program. Public Health Relevance Statement Page 7 ..
  2. Characterization of Exudative Macular Degeneration and Diabetic Retinopathy Using
    Scott E Fraser; Fiscal Year: 2010
    ..The proposed research plan improves the capabilities of PC-OCT and then does a head-to-head comparison with fluorescein angiography in evaluation of patients with wet macular degeneration and diabetic retinopathy. ..
  3. MICROSCOPY & IMAGE ANALYSIS OF UNSTAINED MACROMOLECULES
    Timothy Baker; Fiscal Year: 1992
    ..g. by correcting for phase contrast transfer effects or by averaging very large numbers of particle images), and vii) to phase x-ray crystallographic data with models derived from density maps reconstructed from micrographs...
  4. MICROSCOPY & IMAGE ANALYSIS OF UNSTAINED MACROMOLECULES
    Timothy Baker; Fiscal Year: 1993
    ..g. by correcting for phase contrast transfer effects or by averaging very large numbers of particle images), and vii) to phase x-ray crystallographic data with models derived from density maps reconstructed from micrographs...
  5. MOLECULAR STRUCTURE OF THE 900 KD BOTULINUM NEUROTOXIN COMPLEX
    RAYMOND STEVENS; Fiscal Year: 2002
    ..We will crystallize the 900 kDa complex in the presence of scFv antibody molecules that have a high affinity for exposed regions of the neurotoxin when bound to the 900 kDn complex. ..
  6. MOLECULAR STRUCTURE OF THE 900 KD BOTULINUM NEUROTOXIN COMPLEX
    RAYMOND STEVENS; Fiscal Year: 1999
    ..We will crystallize the 900 kDa complex in the presence of scFv antibody molecules that have a high affinity for exposed regions of the neurotoxin when bound to the 900 kDn complex. ..
  7. MOLECULAR STRUCTURE OF THE 900 KD BOTULINUM NEUROTOXIN COMPLEX
    RAYMOND STEVENS; Fiscal Year: 2000
    ..We will crystallize the 900 kDa complex in the presence of scFv antibody molecules that have a high affinity for exposed regions of the neurotoxin when bound to the 900 kDn complex. ..
  8. MOLECULAR STRUCTURE OF THE 900 KD BOTULINUM NEUROTOXIN COMPLEX
    RAYMOND STEVENS; Fiscal Year: 2001
    ..We will crystallize the 900 kDa complex in the presence of scFv antibody molecules that have a high affinity for exposed regions of the neurotoxin when bound to the 900 kDn complex. ..
  9. MOLECULAR STRUCTURE OF THE 900 KD BOTULINUM NEUROTOXIN COMPLEX
    RAYMOND STEVENS; Fiscal Year: 2001
    ..We will crystallize the 900 kDa complex in the presence of scFv antibody molecules that have a high affinity for exposed regions of the neurotoxin when bound to the 900 kDn complex. ..
  10. MOLECULAR STRUCTURE OF THE 900 KD BOTULINUM NEUROTOXIN COMPLEX
    RAYMOND STEVENS; Fiscal Year: 2002
    ..We will crystallize the 900 kDa complex in the presence of scFv antibody molecules that have a high affinity for exposed regions of the neurotoxin when bound to the 900 kDn complex. ..
  11. MOLECULAR STRUCTURE OF THE 900 KD BOTULINUM NEUROTOXIN COMPLEX
    RAYMOND STEVENS; Fiscal Year: 1999
    ..We will crystallize the 900 kDa complex in the presence of scFv antibody molecules that have a high affinity for exposed regions of the neurotoxin when bound to the 900 kDn complex. ..
  12. Ear Canal Optical Coherent Tomography System
    PAUL SHNITSER; Fiscal Year: 2010
    ..The ECOCT technology will reduce the hearing aid cost (by decreasing the rework to get a better fit), and improve the sound quality, convenience, and comfort of hearing aid use. ..
  13. FULLY THREE-DIMENSIONAL TOMOGRAPHY MEETING
    GRANT GULLBERG; Fiscal Year: 1993
    ....
  14. A New Integrated Endoscope System
    Lih Y Lin; Fiscal Year: 2010
    ..PHS 398/2590 (Rev. 09/04, Reissued 4/2006) Page 1 Continuation Format Page ..
  15. A New Integrated Endoscope System
    LIH LIN; Fiscal Year: 2009
    ..PHS 398/2590 (Rev. 09/04, Reissued 4/2006) Page 1 Continuation Format Page ..
  16. Three-Dimensional Imaging of Whole Cells by Using X-ray Diffraction Microscopy
    Jianwei Miao; Fiscal Year: 2010
    ..This novel imaging technique will be applied to the localization of multiprotein complexes inside whole cells. ..
  17. Three-Dimensional Imaging of Whole Cells by Using X-ray Diffraction Microscopy
    Jianwei Miao; Fiscal Year: 2009
    ..This novel imaging technique will be applied to the localization of multiprotein complexes inside whole cells. ..
  18. Multiphoton Fluorescence Lifetime Imaging of Solid Tumors Invivo
    V Krishnan Ramanujan; Fiscal Year: 2009
    ..These findings will pave a way for monitoring the real-time effects of pharmacological intervention on reducing tumor burden in vivo. ..
  19. Multiphoton Fluorescence Lifetime Imaging of Solid Tumors Invivo
    V Krishnan Ramanujan; Fiscal Year: 2010
    ..These findings will pave a way for monitoring the real-time effects of pharmacological intervention on reducing tumor burden in vivo. ..
  20. High Resolution 3D Optics Coherence Phase Microscopy
    Johannes F de Boer; Fiscal Year: 2010
    ..OCPM will serve as a powerful imaging tool for processes in cell biology and will enhance the understanding of the structure, function, and the behavior of living cells. ..
  21. High Resolution 3D Optics Coherence Phase Microscopy
    Johannes De Boer; Fiscal Year: 2009
    ..OCPM will serve as a powerful imaging tool for processes in cell biology and will enhance the understanding of the structure, function, and the behavior of living cells. ..
  22. Posterior glenohumeral capsule influence on shoulder impingement
    JOHN BORSTAD; Fiscal Year: 2009
    ..The findings of this research are likely to improve shoulder rehabilitation, decrease patient impairment and disability, prevent impingement, and lower health care costs. ..
  23. Posterior glenohumeral capsule influence on shoulder impingement
    JOHN DAVID BORSTAD; Fiscal Year: 2010
    ..The findings of this research are likely to improve shoulder rehabilitation, decrease patient impairment and disability, prevent impingement, and lower health care costs. ..
  24. Posterior glenohumeral capsule influence on shoulder impingement
    JOHN BORSTAD; Fiscal Year: 2007
    ..The findings of this research are likely to improve shoulder rehabilitation, decrease patient impairment and disability, prevent impingement, and lower health care costs. ..
  25. EM STUDIES ON MUSCLE
    KENNETH ALLEN TAYLOR; Fiscal Year: 2011
    ..The molecular basis of stretch activation is unknown. Stretch activation is critical to flight by certain genera of insects making them an excellent model system with which to investigate this phenomenon. ..
  26. THREE DIMENSIONAL STRUCTURE OF ALPHA ACTININ
    Kenneth Taylor; Fiscal Year: 2000
    ..5) Determine conditions that will both produce crystals of one or more alpha-actinin isoforms of a size suitable for an atomic structure analysis and preserve their crystalline order in the electron microscope. ..
  27. THREE DIMENSIONAL STRUCTURE OF ALPHA ACTININ
    Kenneth Taylor; Fiscal Year: 1999
    ..5) Determine conditions that will both produce crystals of one or more alpha-actinin isoforms of a size suitable for an atomic structure analysis and preserve their crystalline order in the electron microscope. ..
  28. DEVELOPING VIRTUAL COLONOSCOPY FOR CANCER SCREENING
    JEROME LIANG; Fiscal Year: 2006
    ..unreadable] [unreadable]..
  29. DEVELOPING VIRTUAL COLONOSCOPY FOR CANCER SCREENING
    JEROME LIANG; Fiscal Year: 2005
    ....
  30. DEVELOPING VIRTUAL COLONOSCOPY FOR CANCER SCREENING
    JEROME LIANG; Fiscal Year: 2007
    ..unreadable] [unreadable]..
  31. STRUCTURAL STUDIES OF BACTERIAL FLAGELLA
    David Derosier; Fiscal Year: 1990
    ..It has been suggested that this structure is an important element of the motor. Freeze-fracture, deep-etch, shadowed replicas of Aquaspirillum serpens and Salmonella typhimurium will be used to visualize the structure...
  32. STRUCTURAL STUDIES OF BACTERIAL FLAGELLA
    David Derosier; Fiscal Year: 1999
    ..It has been suggested that this structure is an important element of the motor. Freeze-fracture, deep-etch, shadowed replicas of Aquaspirillum serpens and Salmonella typhimurium will be used to visualize the structure. ..
  33. Structural Studies of Alphavirus Membrane Fusion In Situ
    Wei Zhang; Fiscal Year: 2009
    ..Knowledge gained from such studies provides potential targets for anti-viral reagents. ..
  34. Structural Studies of Alphavirus Membrane Fusion In Situ
    Wei Zhang; Fiscal Year: 2010
    ..Knowledge gained from such studies provides potential targets for anti-viral reagents. ..
  35. 3-D Imaging Technique for Applications in Anthropome
    PEISEN HUANG; Fiscal Year: 2001
    ..The effectiveness of lung volume reduction surgery (LVRS) will be evaluated. The technique developed in this research should have numerous other medical as well as engineering applications. ..
  36. A MULTI-SCALE APPROACH TO CELL STRUCTURE & FUNCTION
    Andreas Hoenger; Fiscal Year: 2009
    ..The data we will obtain will constitute an essential understanding of cellular processes that may lead to new cures and treatments of many diseases. ..
  37. Optimized whole-lung mapping of the oxygen concentration in human lungs, using Hy
    IULIAN CONSTANTIN RUSET; Fiscal Year: 2010
    ....
  38. Focal Structure-Function Relationships in Macular Layers from 3D Spectral OCT
    MILAN contact SONKA; Fiscal Year: 2010
    ..This study has potentially important consequences for glaucoma, anterior ischemic neural neuropathy, and other retinal disease diagnosis and treatment. ..
  39. 3-D Imaging Technique for Applications in Anthropome
    PEISEN HUANG; Fiscal Year: 2002
    ..The effectiveness of lung volume reduction surgery (LVRS) will be evaluated. The technique developed in this research should have numerous other medical as well as engineering applications. ..
  40. A MULTI-SCALE APPROACH TO CELL STRUCTURE & FUNCTION
    Andreas Hoenger; Fiscal Year: 2010
    ..The data we will obtain will constitute an essential understanding of cellular processes that may lead to new cures and treatments of many diseases. ..
  41. Focal Structure-Function Relationships in Macular Layers from 3D Spectral OCT
    Milan Sonka; Fiscal Year: 2009
    ..This study has potentially important consequences for glaucoma, anterior ischemic neural neuropathy, and other retinal disease diagnosis and treatment. ..
  42. A MULTI-SCALE APPROACH TO CELL STRUCTURE & FUNCTION
    Andreas Hoenger; Fiscal Year: 2010
    ..The data we will obtain will constitute an essential understanding of cellular processes that may lead to new cures and treatments of many diseases. ..
  43. High Resolution Multiplexed Fluorescence Tomography
    MARK JONATHAN NIEDRE; Fiscal Year: 2010
    ..We anticipate that the scanner will have many applications in biomedical research including studying disease development and response to novel therapeutics in vivo. ..
  44. High-Content Image Analysis of Global DNA Methylation Patterns for Drug Screening
    Arkadiusz Gertych; Fiscal Year: 2010
    ..Automatic analysis and quantification of global DNA methylation patterns in individual cells allows the evaluation of drug response and treatment effects. ..
  45. BENIGN PROSTATIC HYPERPLASIA AND PROSTATITIS
    THOMAS PRETLOW; Fiscal Year: 1992
    ..We shall investigate these and other markers to define differences that distinguish these entities from each other and to better understand the biological potentials of these entities...
  46. A SonoKnife for Advanced Cancers
    Eduardo Moros; Fiscal Year: 2009
    ..We called this new technology the SonoKnife, a scanned, line-focused ultrasound thermal therapy system specifically designed for non-invasive thermal ablation. ..
  47. Biomechanics of Spine Fracture
    TONY KEAVENY; Fiscal Year: 2007
    ..abstract_text> ..
  48. Biomechanics of Spine Fracture
    TONY KEAVENY; Fiscal Year: 2005
    ..abstract_text> ..
  49. Biomechanics of Spine Fracture
    TONY KEAVENY; Fiscal Year: 2004
    ..abstract_text> ..
  50. Biomechanics of Spine Fracture
    TONY KEAVENY; Fiscal Year: 2006
    ..abstract_text> ..
  51. Image mapped spectroscopy for snapshot 3-D biomedical imaging
    Mark Pierce; Fiscal Year: 2011
    ..We anticipate that this capability will improve the yield of biopsy collection in screening situations, and provide diagnostic information at locations where tissue could not otherwise be removed. ..
  52. Image Reconstruction Algorithms for Optical Tomography
    JOHN SCHOTLAND; Fiscal Year: 2009
    ..We will utilize the parallel plate imaging geometry which is often employed in optical mammography. The results of this research are expected to impact the design of clinically useful instruments for noncontact optical tomography. ..
  53. Image Reconstruction Algorithms for Optical Tomography
    JOHN SCHOTLAND; Fiscal Year: 2007
    ..We will utilize the parallel plate imaging geometry which is often employed in optical mammography. The results of this research are expected to impact the design of clinically useful instruments for noncontact optical tomography. ..
  54. 3-D ANALYSIS OF LEFT VENTRIULAR REGIONAL WALL MOTION
    R Clark; Fiscal Year: 1990
    ....
  55. HERPESVIRAL ONCOGENESIS, LATENCY AND REACTIVATION
    Nancy Raab Traub; Fiscal Year: 1999
    ..Overall, the program project will continue to dissect the viral/cellular molecular interactions that occur during viral infection and determine how specific molecular events underlie herpes virus pathogenesis. ..
  56. HERPESVIRAL ONCOGENESIS, LATENCY AND REACTIVATION
    Nancy Raab Traub; Fiscal Year: 2003
    ..Overall, the program project will continue to dissect the viral/cellular molecular interactions that occur during viral infection and determine how specific molecular events underlie herpes virus pathogenesis. ..
  57. HERPESVIRAL ONCOGENESIS, LATENCY AND REACTIVATION
    Nancy Raab Traub; Fiscal Year: 2000
    ..Overall, the program project will continue to dissect the viral/cellular molecular interactions that occur during viral infection and determine how specific molecular events underlie herpes virus pathogenesis. ..
  58. HERPESVIRAL ONCOGENESIS, LATENCY AND REACTIVATION
    Nancy Raab Traub; Fiscal Year: 2004
    ..Overall, the program project will continue to dissect the viral/cellular molecular interactions that occur during viral infection and determine how specific molecular events underlie herpes virus pathogenesis. ..
  59. HERPESVIRAL ONCOGENESIS, LATENCY AND REACTIVATION
    Nancy Raab Traub; Fiscal Year: 2001
    ..Overall, the program project will continue to dissect the viral/cellular molecular interactions that occur during viral infection and determine how specific molecular events underlie herpes virus pathogenesis. ..
  60. HERPESVIRAL ONCOGENESIS, LATENCY AND REACTIVATION
    Nancy Raab Traub; Fiscal Year: 2002
    ..Overall, the program project will continue to dissect the viral/cellular molecular interactions that occur during viral infection and determine how specific molecular events underlie herpes virus pathogenesis. ..
  61. BIO-RAD CONFOCAL MICROSCOPE & 3-D ANALYSIS WORK STATION
    Theresa Harrison; Fiscal Year: 1991
    ..Thomas Rosenquist, who is conducting research at a confocal facility at Univ. of South Carolina, will provide expertise and assistance to the other users and technical support in setting up the facility...
  62. C-Arm CT for Guidence of Cardiac Interventions
    Rebecca Fahrig; Fiscal Year: 2009
    ..Access to such images, during an interventional procedure, could also enable new, directed treatments for myocardial infarction by allowing accurate guidance of therapy (cell, drug etc.) directly to the affected tissue. ..
  63. 3D Imaging of electrical activity in myocardial tissue
    Arkady Pertsov; Fiscal Year: 2004
    ..Successful completion of this project will break ground for a new technology, the 3D imaging of electrical activation in the heart. ..
  64. 3D Imaging of electrical activity in myocardial tissue
    Arkady Pertsov; Fiscal Year: 2005
    ..Successful completion of this project will break ground for a new technology, the 3D imaging of electrical activation in the heart. ..
  65. 3D Imaging of electrical activity in myocardial tissue
    Arkady Pertsov; Fiscal Year: 2003
    ..Successful completion of this project will break ground for a new technology, the 3D imaging of electrical activation in the heart. ..
  66. 3D Imaging of electrical activity in myocardial tissue
    Arkady Pertsov; Fiscal Year: 2006
    ..Successful completion of this project will break ground for a new technology, the 3D imaging of electrical activation in the heart. ..
  67. VIRUS ASSEMBLY AND PROTEIN ADAPTABILITY
    DONALD CASPAR; Fiscal Year: 1999
    ....
  68. VIRUS ASSEMBLY AND PROTEIN ADAPTABILITY
    DONALD CASPAR; Fiscal Year: 2000
    ....
  69. MEDICAL IMAGE SEGMENTATION USING KNOWLEDGE OF ANATOMY
    James Brinkley; Fiscal Year: 1992
    ..Because of the fundamental roles that anatomy and structural biology play within the medical sciences, such a knowledge base will have wide applicability in clinical medicine, teaching and basic research...
  70. An Electron Microscope for the study of Complex Biological Assemblies
    MICHAEL ROSSMANN; Fiscal Year: 2006
    ..The instrument would also allow us to perform tomographic studies at about 50 A resolution on pleomorphic viruses and cell organelles that lack structural homogeneity. [unreadable] [unreadable] [unreadable]..
  71. Ophthalmic Imaging Using Adaptive Optics and OCT
    John Werner; Fiscal Year: 2003
    The purpose of this BRP is to develop and evaluate new instrumentation that will permit unprecedented three dimensional imaging of single cells in the human retina, specifically rod and cone photoreceptors and ganglion cells...
  72. LOW-MOLECULAR WEIGHT LIGANDS FOR PROSTATE CANCER
    JOHN FRANGIONI; Fiscal Year: 2002
    ..We believe that prostate- specific, low-molecular weight ligands will someday be clinically useful reagents for improved prostate cancer detection and guided therapy. ..
  73. LOW-MOLECULAR WEIGHT LIGANDS FOR PROSTATE CANCER
    JOHN FRANGIONI; Fiscal Year: 2003
    ..We believe that prostate- specific, low-molecular weight ligands will someday be clinically useful reagents for improved prostate cancer detection and guided therapy. ..
  74. Ophthalmic Imaging Using Adaptive Optics and OCT
    John Werner; Fiscal Year: 2004
    The purpose of this BRP is to develop and evaluate new instrumentation that will permit unprecedented three dimensional imaging of single cells in the human retina, specifically rod and cone photoreceptors and ganglion cells...
  75. LOW-MOLECULAR WEIGHT LIGANDS FOR PROSTATE CANCER
    JOHN FRANGIONI; Fiscal Year: 2000
    ..We believe that prostate- specific, low-molecular weight ligands will someday be clinically useful reagents for improved prostate cancer detection and guided therapy. ..
  76. Ophthalmic Imaging Using Adaptive Optics and OCT
    John Werner; Fiscal Year: 2006
    The purpose of this BRP is to develop and evaluate new instrumentation that will permit unprecedented three dimensional imaging of single cells in the human retina, specifically rod and cone photoreceptors and ganglion cells...
  77. Ophthalmic Imaging Using Adaptive Optics and OCT
    John Werner; Fiscal Year: 2007
    The purpose of this BRP is to develop and evaluate new instrumentation that will permit unprecedented three dimensional imaging of single cells in the human retina, specifically rod and cone photoreceptors and ganglion cells...
  78. Intra-operative specimen tomosynthesis for margin assessment in breast surgery
    EMRE TOKER; Fiscal Year: 2009
    ..system could also serve as a realistic test bed for assessing the clinical efficacy of tomosynthesis in three dimensional imaging of breast tissue, in anticipation of full-breast screening tomosynthesis systems currently under ..