Genomes and Genes
three dimensional imaging
Summary: The process of generating three-dimensional images by electronic, photographic, or other methods. For example, three-dimensional images can be generated by assembling multiple tomographic images with the aid of a computer, while photographic 3-D images (HOLOGRAPHY) can be made by exposing film to the interference pattern created when two laser light sources shine on an object.
Publications262 found, 100 shown here
- Automated manifold surgery: constructing geometrically accurate and topologically correct models of the human cerebral cortexB Fischl
Nuclear Magnetic Resonance Center, Massachusetts General Hospital, Harvard Medical School, Charlestown 02129, USA
IEEE Trans Med Imaging 20:70-80. 2001....
- Sparse MRI: The application of compressed sensing for rapid MR imagingMichael Lustig
Magnetic Resonance Systems Research Laboratory, Department of Electrical Engineering, Stanford University, Stanford, California 94305 9510, USA
Magn Reson Med 58:1182-95. 2007..Examples demonstrate improved spatial resolution and accelerated acquisition for multislice fast spin-echo brain imaging and 3D contrast enhanced angiography...
- MicroCT for developmental biology: a versatile tool for high-contrast 3D imaging at histological resolutionsBrian D Metscher
Department of Theoretical Biology, University of Vienna, Vienna, Austria
Dev Dyn 238:632-40. 2009..These methods establish microCT imaging as a useful tool for comparative developmental studies, embryo phenotyping, and quantitative modeling of development...
- MicroCT for comparative morphology: simple staining methods allow high-contrast 3D imaging of diverse non-mineralized animal tissuesBrian D Metscher
Department of Theoretical Biology, Gerd Müller, University of Vienna, Althanstrasse 14, 1090 Austria
BMC Physiol 9:11. 2009..Although osmium staining and a few other techniques have been used for contrast enhancement, generally useful methods for microCT imaging for comparative morphology are still lacking...
- User-guided 3D active contour segmentation of anatomical structures: significantly improved efficiency and reliabilityPaul A Yushkevich
Penn Image Computing and Science Laboratory, Department of Radiology, University of Pennsylvania, PA 19104 6274, USA
Neuroimage 31:1116-28. 2006..Analogous results for lateral ventricle segmentation are provided...
- Aneurysm growth occurs at region of low wall shear stress: patient-specific correlation of hemodynamics and growth in a longitudinal studyLoic Boussel
Department of Radiology, VA Medical Center, San Francisco, USA 94121, USA
Stroke 39:2997-3002. 2008..Low wall shear stress (WSS) has been reported to have a negative effect on endothelial cells normal physiology and may be an important contributor to local remodeling of the arterial wall and to aneurysm growth and rupture...
- Characterizing of tissue microstructure with single-detector polarization-sensitive optical coherence tomographyBin Liu
Department of Orthopedic Surgery, Brigham and Women s Hospital, Massachusetts, USA
Appl Opt 45:4464-79. 2006..This study, along with the data in part I, advance the insights gained from PS-OCT images beyond simply determining the presence or absence of birefringence...
- New techniques for imaging, digitization and analysis of three-dimensional neural morphology on multiple scalesS L Wearne
Computational Neurobiology and Imaging Center, Mount Sinai School of Medicine, New York, NY 10029 6574, USA
Neuroscience 136:661-80. 2005....
- Discriminating power of localized three-dimensional facial morphologyPeter Hammond
Eastman Dental Institute, University College London, London, WC1X 8LD, United Kingdom
Am J Hum Genet 77:999-1010. 2005....
- Effect of endothelial shear stress on the progression of coronary artery disease, vascular remodeling, and in-stent restenosis in humans: in vivo 6-month follow-up studyPeter H Stone
Cardiovascular Division, Brigham and Women s Hospital, 75 Francis St, Boston, Mass 02115, USA
Circulation 108:438-44. 2003..The endothelium controls local arterial responses by transduction of shear stress. Characterization of endothelial shear stress (ESS) may allow for prediction of progression of atherosclerosis and in-stent restenosis...
- Texture analysis of medical imagesG Castellano
Neuroimage Laboratory, Faculty of Medical Sciences, State University of Campinas, Brazil
Clin Radiol 59:1061-9. 2004..In this article we clarify the principles of texture analysis and give examples of its applications, reviewing studies of the technique...
- The Mouse Limb Anatomy Atlas: an interactive 3D tool for studying embryonic limb patterningApril DeLaurier
Division of Developmental Biology, National Institute for Medical Research, The Ridgeway, Mill Hill, London, UK
BMC Dev Biol 8:83. 2008..Existing textual references consist of two-dimensional (2D) illustrations of the adult rat or mouse limb that can be difficult to apply when attempting to describe the complex three-dimensional (3D) relationship between tissues...
- Anatomically constrained region deformation for the automated segmentation of the hippocampus and the amygdala: Method and validation on controls and patients with Alzheimer's diseaseMarie Chupin
Department of Clinical and Experimental Epilepsy, Institute of Neurology, UCL, UK
Neuroimage 34:996-1019. 2007..The proposed approach provides a new framework for further developments in quantitative analyses of the pathological hippocampus and amygdala in MRI scans...
- The molecular architecture of axonemes revealed by cryoelectron tomographyDaniela Nicastro
Laboratory for 3D Electron Microscopy of Cells, Department of Molecular, Cellular, and Developmental Biology, CB 347, University of Colorado, Boulder, CO 80309 0347, USA
Science 313:944-8. 2006..Periodic densities were also observed inside doublet microtubules; these may contribute to doublet stability...
- Accuracy of three-dimensional measurements obtained from cone beam computed tomography surface-rendered images for cephalometric analysis: influence of patient scanning positionBassam Hassan
Department of Oral Radiology, Academic Centre for Dentistry Amsterdam ACTA, The Netherlands
Eur J Orthod 31:129-34. 2009..The findings indicate that measurements based on 3D CBCT surface images are accurate and that small variations in the patient's head position do not influence measurement accuracy...
- High-throughput morphologic phenotyping of the mouse brain with magnetic resonance histologyG Allan Johnson
Center for In Vivo Microscopy, Box 3302, Duke University Medical Center, Durham, NC 27710, USA
Neuroimage 37:82-9. 2007..These collection and acquisition methods are now available to the neuroscience community as a standard web-deliverable service...
- Visualizing and clustering high throughput sub-cellular localization imagingNicholas A Hamilton
ARC Centre of Excellence in Bioinformatics, The University of Queensland, Brisbane, Queensland 4072, Australia
BMC Bioinformatics 9:81. 2008..The result is images that are statistically similar are spatially close in the visualization allowing for easy comparison of images that are similar and distinguishment of dissimilar images into distinct clusters...
- Tumor volume in pharyngolaryngeal squamous cell carcinoma: comparison at CT, MR imaging, and FDG PET and validation with surgical specimenJean François Daisne
Head and Neck Oncology Program, St Luc University Hospital, Universite Catholique de Louvain, 10 Ave Hippocrate, 1200 Brussels, Belgium
Radiology 233:93-100. 2004....
- Multicell simulations of development and disease using the CompuCell3D simulation environmentMaciej H Swat
Biocomplexity Institute and Department of Physics, Indiana University, Bloomington, USA
Methods Mol Biol 500:361-428. 2009..This tutorial introduces Glazier-Graner-Hogeweg (GGH) multicell simulations and CompuCell3D, a simulation framework that allows users to build, test, and run GGH simulations...
- Tomographic molecular imaging and 3D quantification within adult mouse organsTomas Alanentalo
Umeå Center for Molecular Medicine, Umea University, S 901 87, Umea, Sweden
Nat Methods 4:31-3. 2007..Using the nonobese diabetic (NOD) mouse model, we demonstrate a correlation between total islet beta-cell volume and the onset of type-1 diabetes...
- Direct three-dimensional myocardial strain tensor quantification and tracking using zHARPKhaled Z Abd-Elmoniem
Department of Radiology and Radiological Sciences, School of Medicine, Johns Hopkins University, Baltimore, MD 21287, USA
Med Image Anal 12:778-86. 2008..The performance and accuracy of the method is demonstrated in vitro on a phantom and in vivo in four healthy adult human subjects...
- Ultrahigh-resolution full-field optical coherence tomographyArnaud Dubois
Laboratoire d Optique Physique, Ecole Superieure de Physique et Chimie Industrielles, Centre National de la Recherche Scientifique, Unité Propre de Recherche A0005, 10 rue Vauquelin, F 75231 Paris Cedex 5, France
Appl Opt 43:2874-83. 2004..A shot-noise-limited detection sensitivity of 90 dB is obtained in an acquisition time per image of 4 s. Subcellular-level images of plant, animal, and human tissues are presented...
- Rigid registration of 3-D ultrasound with MR images: a new approach combining intensity and gradient informationA Roche
INRIA Projet Epidaure, Sophia Antipolis, France
IEEE Trans Med Imaging 20:1038-49. 2001..A cross-validation study has been carried out using a number of phantom and clinical data. This indicates that the method is quite robust and that the worst registration errors are of the order of the MR image resolution...
- Nodavirus coat protein imposes dodecahedral RNA structure independent of nucleotide sequence and lengthMariana Tihova
Department of Cell Biology, The Scripps Research Institute, Scripps Clinic, La Jolla, California 92037, USA
J Virol 78:2897-905. 2004..We propose that the capsid protein is able to exploit the plasticity of the RNA secondary structures, capturing those that are compatible with the geometry of the dodecahedral cage...
- Regional deficits in brain volume in schizophrenia: a meta-analysis of voxel-based morphometry studiesRobyn Honea
Prince of Wales International Centre for SANE Research, Department of Psychiatry, University of Oxford, Warneford Hospital, Headington, Oxford, UK OX3 7JX
Am J Psychiatry 162:2233-45. 2005....
- New magnetic resonance imaging-based method for defining the extent of left atrial wall injury after the ablation of atrial fibrillationChristopher J McGann
Radiology Department, University of Utah School of Medicine, University of Utah, Salt Lake City, Utah, USA
J Am Coll Cardiol 52:1263-71. 2008..Using a 3-dimensional (3D) delayed-enhancement magnetic resonance imaging (MRI) sequence and novel processing methods, LA wall scarring is visualized at high resolution after radiofrequency ablation (RFA)...
- Recommendations from Gynaecological (GYN) GEC-ESTRO Working Group (I): concepts and terms in 3D image based 3D treatment planning in cervix cancer brachytherapy with emphasis on MRI assessment of GTV and CTVChristine Haie-Meder
Department of Radiotherapy, Brachytherapy Unit, Institut Gustave Roussy, 39 rue Camille Desmoulins, 94805 Villejuif, France
Radiother Oncol 74:235-45. 2005..When introducing a 3D image based approach for GTV and CTV assessment, there is a need for a common language to describe the concepts and to define the terms which are to be used...
- Measurement of myocardial mechanics in mice before and after infarction using multislice displacement-encoded MRI with 3D motion encodingWesley D Gilson
Department of Biomedical Engineering, University of Virginia, Charlottesville, Virginia 22908, USA
Am J Physiol Heart Circ Physiol 288:H1491-7. 2005..07 +/- 0.54 degrees /mm (R = 0.96, P < 0.05). DENSE MRI can assess the 3D myocardial mechanics of the murine heart in <1 h of scan time at 4.7 T and may be applied to studies of myocardial mechanics in genetically engineered mice...
- Magnitude and role of wall shear stress on cerebral aneurysm: computational fluid dynamic study of 20 middle cerebral artery aneurysmsMasaaki Shojima
Department of Neurosurgery, Faculty of Medicine, University of Tokyo, Japan
Stroke 35:2500-5. 2004..The magnitude and distribution of the WSS in and around human middle cerebral artery (MCA) aneurysms were analyzed using the method of computed fluid dynamics (CFD)...
- Image-based computational fluid dynamics modeling in realistic arterial geometriesDavid A Steinman
Imaging Research Laboratories, The John P Robarts Research Institute, The University of Western Ontario, London, Canada
Ann Biomed Eng 30:483-97. 2002..Issues related to accuracy, precision, and modeling assumptions are also discussed...
- False discovery rate revisited: FDR and topological inference using Gaussian random fieldsJustin R Chumbley
Wellcome Trust Centre for Neuroimaging, University College London, London, UK
Neuroimage 44:62-70. 2009..We describe the nature of the problem, illustrate it with some examples and suggest a simple solution based on controlling the false discovery rate of connected excursion sets within an SPM, characterised by their volume...
- Detection and quantification of left atrial structural remodeling with delayed-enhancement magnetic resonance imaging in patients with atrial fibrillationRobert S Oakes
Atrial Fibrillation Program, University of Utah School of Medicine, Salt Lake City, UT 84132 2400, USA
Circulation 119:1758-67. 2009..In this study, we report the utility of delayed-enhancement magnetic resonance imaging (DE-MRI) in detecting abnormal atrial tissue before radiofrequency ablation and in predicting procedural outcome...
- Global brain atrophy and corticospinal tract alterations in ALS, as investigated by voxel-based morphometry of 3-D MRIJan Kassubek
Department of Neurology, University of Ulm, Germany
Amyotroph Lateral Scler Other Motor Neuron Disord 6:213-20. 2005..VBM might be a potential tool to visualize disease progression in future longitudinal studies...
- Time-resolved contrast-enhanced three-dimensional magnetic resonance angiography of the chest: combination of parallel imaging with view sharing (TREAT)Christian Fink
Abteilung Radiologie, Deutsches Krebsforschungszentrum DKFZ, Innovative Krebsdiagnostik und Therapie, Heidelberg, Germany
Invest Radiol 40:40-8. 2005....
- Validity and reliability of craniofacial anthropometric measurement of 3D digital photogrammetric imagesJulielynn Y Wong
Craniofacial Centre, Division of Plastic Surgery, Children s Hospital, Harvard Medical School, Boston, MA, USA
Cleft Palate Craniofac J 45:232-9. 2008..Before morphometry using digital photogrammetry can be applied in clinical and research practice, it must be assessed against direct anthropometry...
- What is cone-beam CT and how does it work?William C Scarfe
Department of Surgical Hospital Dentistry, University of Louisville School of Dentistry, 501 South Preston Street, Louisville, KY 40292, USA
Dent Clin North Am 52:707-30, v. 2008..Future enhancements most likely will be directed toward reducing scan time; providing multimodal imaging; improving image fidelity, including soft tissue contrast; and incorporating task-specific protocols to minimize patient dose...
- Evaluation of lung volumetry using dynamic three-dimensional magnetic resonance imagingChristian Plathow
Department of Radiology, German Cancer Research Center, Heidelberg, Germany
Invest Radiol 40:173-9. 2005..We sought to investigate lung volume and surface measurements during the breathing cycle using dynamic three-dimensional magnetic resonance imaging (3D MRI)...
- 3D analysis of facial morphologyPeter Hammond
Eastman Dental Institute, UCL, London, United Kingdom
Am J Med Genet A 126:339-48. 2004..This article contains supplementary material, which may be viewed at the American Journal of Medical Genetics website at http://www.interscience.wiley.com/jpages/0148-7299/suppmat/index.html...
- Quantitative comparison of algorithms for inter-subject registration of 3D volumetric brain MRI scansBabak A Ardekani
Center for Advanced Brain Imaging, Nathan Kline Institute for Psychiatric Research, 140 Old Orangeburg Road, Orangeburg, NY 10962, USA
J Neurosci Methods 142:67-76. 2005..The spatial dispersion measure was found to be more sensitive when the landmarks were placed after image registration. The standard deviation measure was found sensitive to intensity normalization or the method of image interpolation...
- A new technique for the creation of a computerized composite skull modelJaime Gateno
Department of Oral and Maxillofacial Surgery, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA
J Oral Maxillofac Surg 61:222-7. 2003..The computerized composite skull model is the combination of a 3-dimensional (3D) computed tomography (CT) bone model with digital dental models...
- Accelerating molecular modeling applications with graphics processorsJOHN E STONE
Beckman Institute, University of Illinois at Urbana Champaign, Urbana, IL 61801, USA
J Comput Chem 28:2618-40. 2007..In light of the performance obtained for this set of calculations, future applications of graphics processors to molecular dynamics simulations are discussed...
- Atlas renormalization for improved brain MR image segmentation across scanner platformsXiao Han
Athinoula A Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA
IEEE Trans Med Imaging 26:479-86. 2007....
- Fluid-structure interaction within realistic three-dimensional models of the aneurysmatic aorta as a guidance to assess the risk of rupture of the aneurysmE S Di Martino
Department of Bioengineering, Politecnico of Milano, Milan, Italy
Med Eng Phys 23:647-55. 2001..A proven clinical efficacy may promote the method as a tool to determine factual aneurysm risk of rupture and aid the surgeon to refer elective surgery patients...
- The use of a new 3D splint and double CT scan procedure to obtain an accurate anatomic virtual augmented model of the skullG R J Swennen
Division of Maxillo Facial Surgery, Department of Surgery, General Hospital St Jan Bruges, Rudershove 10, 8000 Bruges, Belgium
Int J Oral Maxillofac Surg 36:146-52. 2007..0491-0.0622). The combination of the newly designed 3D splint with the double CT scan procedure allowed accurate registration and the set-up of an accurate anatomic 3D virtual augmented model of the skull with detailed dental surface...
- Sources and effects of electrode impedance during deep brain stimulationChristopher R Butson
Department of Biomedical Engineering, Cleveland Clinic Foundation, 9500 Euclid Ave ND 20, Cleveland, OH 44195, USA
Clin Neurophysiol 117:447-54. 2006....
- Second-harmonic imaging microscopy of normal human and keratoconus corneaNaoyuki Morishige
The Eye Institute, School of Medicine, University of California Irvine Medical Center, Orange, California
Invest Ophthalmol Vis Sci 48:1087-94. 2007..The purpose of this study was to evaluate the ability of second-harmonic imaging to identify differences in corneal stromal collagen organization between normal human and keratoconus corneas...
- 3D MRI-based multicomponent FSI models for atherosclerotic plaquesDalin Tang
Mathematical Sciences Department, Worcester Polytechnic Institute, Worcester, MA 01609, USA
Ann Biomed Eng 32:947-60. 2004..Large-scale patient studies are needed to validate the computational findings for possible plaque vulnerability assessment and rupture predictions...
- Automatic segmentation of cortical and trabecular compartments based on a dual threshold technique for in vivo micro-CT bone analysisHelen R Buie
Department of Mechanical and Manufacturing Engineering, Schulich School of Engineering, University of Calgary, 2500 University Drive N W, Calgary, Alberta, Canada T2N 1N4
Bone 41:505-15. 2007..Using the same input thresholds for similar datasets assures maximal consistency while alleviating time consuming semi-automated contouring...
- A layer-specific three-dimensional model for the simulation of balloon angioplasty using magnetic resonance imaging and mechanical testingGerhard A Holzapfel
Institute for Structural Analysis Computational Biomechanics, Graz University of Technology, Austria
Ann Biomed Eng 30:753-67. 2002....
- Globally optimal stitching of tiled 3D microscopic image acquisitionsStephan Preibisch
Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany
Bioinformatics 25:1463-5. 2009..The physical coordinates provided by the microscope stage are not precise enough to allow direct reconstruction (Stitching) of the whole image from individual image stacks...
- Whole-heart steady-state free precession coronary artery magnetic resonance angiographyOliver M Weber
Department of Radiology, University of California San Francisco, San Francisco, California 94143, USA
Magn Reson Med 50:1223-8. 2003..It is concluded that the whole-heart coronary MRA technique improves visible vessel length and facilitates high-quality coronary MRA of the complete coronary artery tree in a single measurement...
- Hippocampal head size associated with verbal memory performance in nondemented elderlyV H Hackert
Department of Epidemiology and Biostatistics, Erasmus Medical Center, Rotterdam, The Netherlands
Neuroimage 17:1365-72. 2002..06, 0.59)). Our data suggest selective involvement of the hippocampal head in verbal memory, and add to recent findings of functional segregation along the longitudinal axis of the hippocampus...
- Estimating linear cortical magnification in human primary visual cortex via dynamic programmingAnqi Qiu
Center for Imaging Science, Johns Hopkins University, Baltimore, MD 21218, USA
Neuroimage 31:125-38. 2006..The reliability of these estimates was assessed by comparing results based on data from one quadrant to those based on data from the full hemifield along with a split-half reliability analysis...
- A novel method for the 3-dimensional simulation of orthognathic surgery by using a multimodal image-fusion techniqueJun Uechi
Department of Orthodontics, School of Dentistry, Health Sciences University of Hokkaido, Ishikari Tobetsu, Japan
Am J Orthod Dentofacial Orthop 130:786-98. 2006..The aim of this study was to establish a novel method for simulating orthognathic surgery in 3-dimensional (3D) space...
- Methods of assessment of cleft-related facial deformity: a reviewI Al-Omari
University of Jordan Dental School, Amman, Jordan
Cleft Palate Craniofac J 42:145-56. 2005..To review the stimulus media, measurements and scoring system, rater's characteristics, and facial region used in assessment of the appearance of cleft-related deformity...
- Completing the 3-dimensional pictureChristopher Lane
Am J Orthod Dentofacial Orthop 133:612-20. 2008..These 3D systems enable extraoral imaging protocols to be equally precise in providing highly accurate 3D facial surface images for diagnosis, analysis, treatment monitoring, simulation, and outcome evaluation...
- Sex-based differences in the anthropometric characteristics of the anterior cruciate ligament and its relation to intercondylar notch geometry: a cadaveric studyNaveen Chandrashekar
Mechanical Engineering Department, Texas Tech University, Lubbock, TX 79409, USA
Am J Sports Med 33:1492-8. 2005..Reasons for this disparity are not well understood; however, sex-based differences in the geometry of the anterior cruciate ligament, its morphologic characteristics, and the intercondylar notch size have been cited as possible factors...
- Fast high-resolution T1 mapping of the human brainRalf Deichmann
Wellcome Department of Imaging Neuroscience, Institute of Neurology, London, UK
Magn Reson Med 54:20-7. 2005..In addition, an improved fitting algorithm based on smoothed flip angle maps is presented and tested successfully...
- Myocardial 3D strain calculation by combining cine displacement encoding with stimulated echoes (DENSE) and cine strain encoding (SENC) imagingAaron T Hess
Department of Human Biology, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa
Magn Reson Med 62:77-84. 2009..42 +/-0.11, -0.10 +/-0.03, and -0.21 +/-0.02, respectively. These results show that this technique is capable of reliably quantifying 3D cardiac strain...
- 3D structure of eukaryotic flagella in a quiescent state revealed by cryo-electron tomographyDaniela Nicastro
Abteilung Molekulare Strukturbiologie, Max Planck Institut fur Biochemie, 82152 Martinsried, Germany
Proc Natl Acad Sci U S A 102:15889-94. 2005..Cryo-electron tomography has proven to be a powerful technique for helping us understand the relationships between flagellar structure and function and the design of macromolecular machines in situ...
- Assessment of bone segmentation quality of cone-beam CT versus multislice spiral CT: a pilot studyMiet Loubele
Medical Image Computing ESAT Radiology, Faculties of Engineering and Medicine, K U Leuven, Leuven, Belgium
Oral Surg Oral Med Oral Pathol Oral Radiol Endod 102:225-34. 2006..The objective of this study was to quantitatively assess the quality of jawbone models generated from cone beam computed tomography (CBCT) by comparison with similar models obtained from multislice spiral computed tomography (MSCT)...
- Rapid automated three-dimensional tracing of neurons from confocal image stacksKhalid A Al-Kofahi
Electrical, Computer, and Systems Engineering Department, Rensselaer Polytechnic Institute, Troy, NY 12180 3590, USA
IEEE Trans Inf Technol Biomed 6:171-87. 2002..These properties make it attractive for large-scale automated tissue studies that require rapid on-line image analysis, such as high-throughput neurobiology/angiogenesis assays, and initiatives such as the Human Brain Project...
- Accuracy of CT-based thickness measurement of thin structures: modeling of limited spatial resolution in all three dimensionsSven Prevrhal
Osteoporosis and Arthritis Research Group, Department of Radiology, University of California San Francisco, San Francisco, California 94117, USA
Med Phys 30:1-8. 2003....
- 3D micro-CT imaging of the postmortem brainAlex de Crespigny
Athinoula A Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, MA 02129, USA
J Neurosci Methods 171:207-13. 2008..For simple measurements, such as tumor volume and non-destructive postmortem brain screening, microCT may prove to be a valuable alternative to standard histopathology or microMRI...
- Inter- and intraobserver variation in HR-CTV contouring: intercomparison of transverse and paratransverse image orientation in 3D-MRI assisted cervix cancer brachytherapyPrimoz Petric
Department of Radiotherapy and Radiobiology, Medical University of Vienna, Vienna, Austria
Radiother Oncol 89:164-71. 2008..To analyze agreement between target volumes, delineated by two observers on transverse (T) and paratransverse (perpendicular to the long cervical axis - PT) MR images for cervix cancer brachytherapy...
- Evaluation of reproducibility and reliability of 3D soft tissue analysis using 3D stereophotogrammetryJ M Plooij
3D Facial Imaging Research Group Nijmegen Bruges 3D FIRG, Department of Oral and Maxillofacial Surgery, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
Int J Oral Maxillofac Surg 38:267-73. 2009..This shows that hard tissue data are not needed to perform accurate soft tissue analysis...
- An Eulerian PDE approach for computing tissue thicknessAnthony J Yezzi
School of Electrical and Computer Engineering, Georgia Institute of Technology, Atlanta, GA 30322, USA
IEEE Trans Med Imaging 22:1332-9. 2003..These experiments reveal very good performance and show strong potential for application in tissue thickness visualization and quantification...
- Morphogenesis and oncogenesis of MCF-10A mammary epithelial acini grown in three-dimensional basement membrane culturesJayanta Debnath
Department of Cell Biology, Harvard Medical School, 240 Longwood Avenue, Boston, MA 02115, USA
Methods 30:256-68. 2003....
- Wall shear stress on ruptured and unruptured intracranial aneurysms at the internal carotid arteryL D Jou
Department of Radiology, Baylor College of Medicine, Houston, TX 77030, USA
AJNR Am J Neuroradiol 29:1761-7. 2008..Flow impingement, greater pressure, and abnormal wall shear stress are all indications for aneurysm rupture. Characterizing wall shear stress for intracranial aneurysms at similar anatomic locations may help in understanding its role...
- Usefulness of three-dimensional, multidetector row CT (virtual gastroscopy and multiplanar reconstruction) in the evaluation of gastric cancer: a comparison with conventional endoscopy, EUS, and histopathologySuryaprakash Bhandari
Institute for Digestive Research and Department of Radiology, Soon Chun Hyang University College of Medicine, Seoul, South Korea
Gastrointest Endosc 59:619-26. 2004..The aim of this study was to assess the role of three-dimensional multidetector row CT for detection, precise localization, and staging of gastric cancer by comparison with conventional endoscopy, EUS, and histopathology...
- Three-dimensional coronary MR angiography performed with subject-specific cardiac acquisition windows and motion-adapted respiratory gatingSven Plein
British Heart Foundation Cardiac MRI Unit, Rm 170, D Fl, Jubilee Building, Leeds General Infirmary, Great George Street, Leeds LS1 3EX, United Kingdom
AJR Am J Roentgenol 180:505-12. 2003..We hypothesized that a more flexible and subject-specific approach to cardiac and respiratory gating may shorten scanning times while maintaining image quality...
- Two-photon 3-D mapping of ex vivo human skin endogenous fluorescence species based on fluorescence emission spectraLily H Laiho
Massachusetts Institute of Technology, Department of Mechanical Engineering, 77 Massachusetts Avenue, NE47 276, Cambridge, Massachusetts 02139, USA
J Biomed Opt 10:024016. 2005..Luminescence species identified include tryptophan, NAD(P)H, melanin, and elastin, which are autofluorescent, and collagen that contributes to a second harmonic signal...
- Gastric cancer: preoperative local staging with 3D multi-detector row CT--correlation with surgical and histopathologic resultsChiao Yun Chen
Department of Medical Imaging, Kaohsiung Medical University, Chung Ho Memorial Hospital, 100 Tz You 1st Road, Kaohsiung, Taiwan
Radiology 242:472-82. 2007..To prospectively evaluate accuracy of multi-detector row computed tomographic (CT) images for preoperative staging of gastric cancer by using surgical and histopathologic results as reference standards...
- The three-dimensional micro- and nanostructure of the aortic medial lamellar unit measured using 3D confocal and electron microscopy imagingMary K O'Connell
Department of Mechanical Engineering, Stanford University, Stanford, CA, USA
Matrix Biol 27:171-81. 2008..This high resolution three-dimensional view of the aortic media reveals MLU microstructure details that suggest a highly complex and integrated mural organization that correlates with aortic mechanical properties...
- Three-dimensional cone-beam computed tomography for assessment of mandibular changes after orthognathic surgeryLucia H S Cevidanes
Department of Orthodontics, School of Dentistry, University of North Carolina, Chapel Hill, NC 27599 7450, USA
Am J Orthod Dentofacial Orthop 131:44-50. 2007..The purpose of this study was to assess alterations in the 3-dimensional (3D) position of the mandibular rami and condyles in patients receiving either maxillary advancement and mandibular setback or maxillary surgery only...
- New methods of MR image intensity standardization via generalized scaleAnant Madabhushi
Department of Biomedical Engineering, Rutgers The State University of New Jersey, 617 Bowser Road, Room 101, Piscataway, New Jersey 08854, USA
Med Phys 33:3426-34. 2006..The new scale-based methods were found to be better than the existing methods, with a significant improvement observed for severely diseased and abnormal patient studies...
- Analysis of barley (Hordeum vulgare) grain development using three-dimensional digital modelsSabine Gubatz
Leibniz Institute of Plant Genetics and Crop Plant Research IPK, Corrensstr 3, D 06466, Gatersleben, Germany
Plant J 52:779-90. 2007..At anthesis, mRNA of the protease nucellin was visualized in a distinct zone of the nucellus near the antipodal cells...
- Airflow limitation and airway dimensions in chronic obstructive pulmonary diseaseMasaru Hasegawa
First Department of Medicine, Hokkaido University School of Medicine, N 15 W 7 Kita ku, Sapporo 060 8638, Japan
Am J Respir Crit Care Med 173:1309-15. 2006..Computed tomography has been widely used to assess emphysema severity, but less attention has been paid to the assessment of airway disease using computed tomography...
- Polyp detection with CT colonography: primary 3D endoluminal analysis versus primary 2D transverse analysis with computer-assisted reader softwareStuart A Taylor
Department of Intestinal Imaging, St Mark s Hospital, Northwick Park, Harrow, United Kingdom
Radiology 239:759-67. 2006....
- Detecting molecular interactions that stabilize native bovine rhodopsinK Tanuj Sapra
Center for Biotechnology, University of Technology, 01307 Dresden, Germany
J Mol Biol 358:255-69. 2006..These changes highlight the structural importance of this disulfide bond and may form the basis of dysfunctions associated with its absence...
- Three-dimensional endomicroscopy of the human colon using optical coherence tomographyDesmond C Adler
Department of Electrical Engineering and Computer Science, and Research Laboratory of Electronics, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA
Opt Express 17:784-96. 2009..This clinical pilot study demonstrates the potential of 3D-OCT for distinguishing normal from pathologic colorectal tissue, assessing endoscopic therapies and healing progression...
- Fast isotropic volumetric coronary MR angiography using free-breathing 3D radial balanced FFE acquisitionC Stehning
Institute of Biomedical Engineering IBT, Karlsruhe, Germany
Magn Reson Med 52:197-203. 2004..The scan time ranged from 10 to 14 min during free breathing at a heart rate of 60 bpm, which is comparable to that of a thin-slab protocol comprising multiple scans for each coronary artery...
- The interobserver reliability and validity of volume calculation from three-dimensional ultrasound datasets in the in vitro settingN J Raine-Fenning
School of Human Development, Academic Division of Reproductive Medicine, Queens Medical Centre, Nottingham, UK
Ultrasound Obstet Gynecol 21:283-91. 2003....
- Can PET provide the 3D extent of tumor motion for individualized internal target volumes? A phantom study of the limitations of CT and the promise of PETCurtis B Caldwell
Sunnybrook and Women s College Health Sciences Centre, Toronto, Ontario, Canada
Int J Radiat Oncol Biol Phys 55:1381-93. 2003....
- Multiplanar and three-dimensional multi-detector row CT of thoracic vessels and airways in the pediatric populationMarilyn J Siegel
Edward Mallinckrodt Institute of Radiology, Washington University School of Medicine, 510 S Kingshighway Blvd, St Louis, MO 63110, USA
Radiology 229:641-50. 2003....
- A study of diffusion tensor imaging by tissue-specific, smoothing-compensated voxel-based analysisJee Eun Lee
Waisman Laboratory for Brain Imaging and Behavior, Waisman Center, Madison, WI 53705, USA
Neuroimage 44:870-83. 2009..The T-SPOON method may be also applicable to other quantitative imaging maps such as T1 or T2 relaxometry, magnetization transfer, or PET tracer maps...
- Serial registration of intraoperative MR images of the brainMatthieu Ferrant
Communications and Remote Sensing Laboratory, Universite Catholique de Louvain, B 1348, Louvain la Neuve, Belgium
Med Image Anal 6:337-59. 2002..7+/-0.6 mm (mean+/-S.D.) for boundary surface landmarks, of 0.9+/-0.6 mm for landmarks inside the boundary surfaces, and 1.6+/-0.9 mm for landmarks in the vicinity of the tumor...
- eF-site and PDBjViewer: database and viewer for protein functional sitesKengo Kinoshita
Graduate School of Integrated Science, Yokohama City University, 1 7 29 Suehiro cho, Tsurumi ku, Yokohama, 230 0045, Japan
Bioinformatics 20:1329-30. 2004..To enable browsing of each molecular surface along with the atomic model, we have developed a new three-dimensional interactive viewer, PDBjViewer, that can be used both as an applet and as a stand-alone program...
- Registration of 3-D intraoperative MR images of the brain using a finite-element biomechanical modelM Ferrant
Communications and Remote Sensing Laboratory, Universite Catholique de Louvain, Louvain la Neuve, Belgium
IEEE Trans Med Imaging 20:1384-97. 2001..Cortical surface shifts of up to 10 mm and subsurface shifts of up to 6 mm were recovered with an accuracy of 1 mm or less and 3 mm or less respectively...
- Mutual-information-based registration of medical images: a surveyJosien P W Pluim
University Medical Center Utrecht, Image Sciences Institute, Room E01 335, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands
IEEE Trans Med Imaging 22:986-1004. 2003..Comparison studies including mutual information are also considered. The paper starts with a description of entropy and mutual information and it closes with a discussion on past achievements and some future challenges...
- Visualization of flow patterns distal to aortic valve prostheses in humans using a fast approach for cine 3D velocity mappingS Kozerke
Institute of Biomedical Engineering, University of Zurich and Swiss Federal Institute of Technology, Switzerland
J Magn Reson Imaging 13:690-8. 2001..It is concluded that MR velocity mapping is a potential tool for studying 3D flow patterns evolving around heart valve prostheses in humans. J. Magn. Reson. Imaging 2001;13:690-698...
- The impact of contouring uncertainty on rectal 3D dose-volume data: results of a dummy run in a multicenter trial (AIROPROS01-02)Franca Foppiano
Department of Medical Physics, National Cancer Research Institute, Genova, Italy
Int J Radiat Oncol Biol Phys 57:573-9. 2003..To estimate the impact of the uncertainty in contouring the rectum on rectal dose-volume parameters and normal tissue complication probability (NTCP) in a prospective (AIROPROS01-02) investigation about rectal toxicity...
- Value of three-dimensional US for optimizing guidance for ablating focal liver tumorsS C Rose
Department of Radiology, University of California Medical Center, 200 West Arbor Drive, San Diego, CA 92103, USA
J Vasc Interv Radiol 12:507-15. 2001....
- Nonrigid registration of 3D tensor medical dataJ Ruiz-Alzola
Medical Technology Center, University of Las Palmas de Gran Canaria and Gran Canaria Dr Negrín Hospital, Spain
Med Image Anal 6:143-61. 2002..The feasibility of the approach is illustrated by results on synthetic and clinical data...
- Navigator-gated coronary magnetic resonance angiography using steady-state-free-precession: comparison to standard T2-prepared gradient-echo and spiral imagingElmar Spuentrup
Department of Diagnostic Radiology, Technical University of Aachen, Aachen, Germany
Invest Radiol 38:263-8. 2003..The purpose of this study was a systematic comparison of SSFP cMRA with standard T2-prepared gradient-echo and spiral cMRA...
- Three-dimensional adaptive filtering in magnetic resonance angiographyC F Westin
Surgical Planning Laboratory, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA
J Magn Reson Imaging 14:63-71. 2001..9 dB) were observed. 3D adaptive filtering may provide an alternative to prolonging the scan time or using contrast agents in MRA when the CNR is low...
- Navigator-gated free-breathing three-dimensional balanced fast field echo (TrueFISP) coronary magnetic resonance angiographyElmar Spuentrup
Department of Medicine Cardiovascular Division, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts, USA
Invest Radiol 37:637-42. 2002..It is hypothesized that Balanced-FFE may be valuable for contrast enhancement in 3D free-breathing coronary MRA...
- Improved visualization of coronary arteries using a new three-dimensional submillimeter MR coronary angiography sequence with balanced gradientsBenedetta Giorgi
Department of Radiology, Gasthuisberg University Hospital, Catholic University of Leuven, Herestraat 49, B 3000 Leuven, Belgium
AJR Am J Roentgenol 179:901-10. 2002..The goal of our study was to evaluate a new three-dimensional real-time navigator MR coronary angiography sequence to noninvasively visualize the coronary arteries...
- Effects of noise, image resolution, and ROI definition on the accuracy of standard uptake values: a simulation studyRonald Boellaard
PET Center, VU University Medical Center, Amsterdam, The Netherlands
J Nucl Med 45:1519-27. 2004..Therefore, an experimental and simulation study was performed to determine the effects of noise, image resolution, and region-of-interest (ROI) definition on the accuracy of SUVs...
- Biphasic tissue Doppler waveforms during isovolumic phases are associated with asynchronous deformation of subendocardial and subepicardial layersPartho P Sengupta
Division of Cardiovascular Diseases, Mayo Clinic Rochester, 200 First St SW, Rochester, MN 55905, USA
J Appl Physiol 99:1104-11. 2005..The results support an association between asynchronous deformation of subendocardial and subepicardial muscle fibers and the biphasic isovolumic movements observed with high-resolution tissue Doppler imaging...
- Accuracy of finite element model-based multi-organ deformable image registrationK K Brock
Radiation Medicine Program, Princess Margaret Hospital, University Health Network, 610 University Avenue, Toronto, Ontario, Canada M5G 2M9
Med Phys 32:1647-59. 2005....
- Office based Real-time high Speed 3-D OCT system for Diagnosis of EarlyLaryngealTIRUNELVELI RAMALINGAM; Fiscal Year: 2010..Out technology which was developed in the laboratory is now being transferred to market place through OCTMI. Hence this proposal in ideal for PA-08-114 program. Public Health Relevance Statement Page 7 ..
- Characterization of Exudative Macular Degeneration and Diabetic Retinopathy UsingScott E Fraser; Fiscal Year: 2010..The proposed research plan improves the capabilities of PC-OCT and then does a head-to-head comparison with fluorescein angiography in evaluation of patients with wet macular degeneration and diabetic retinopathy. ..
- MICROSCOPY & IMAGE ANALYSIS OF UNSTAINED MACROMOLECULESTimothy Baker; Fiscal Year: 1992..g. by correcting for phase contrast transfer effects or by averaging very large numbers of particle images), and vii) to phase x-ray crystallographic data with models derived from density maps reconstructed from micrographs...
- MICROSCOPY & IMAGE ANALYSIS OF UNSTAINED MACROMOLECULESTimothy Baker; Fiscal Year: 1993..g. by correcting for phase contrast transfer effects or by averaging very large numbers of particle images), and vii) to phase x-ray crystallographic data with models derived from density maps reconstructed from micrographs...
- MOLECULAR STRUCTURE OF THE 900 KD BOTULINUM NEUROTOXIN COMPLEXRAYMOND STEVENS; Fiscal Year: 2002..We will crystallize the 900 kDa complex in the presence of scFv antibody molecules that have a high affinity for exposed regions of the neurotoxin when bound to the 900 kDn complex. ..
- MOLECULAR STRUCTURE OF THE 900 KD BOTULINUM NEUROTOXIN COMPLEXRAYMOND STEVENS; Fiscal Year: 1999..We will crystallize the 900 kDa complex in the presence of scFv antibody molecules that have a high affinity for exposed regions of the neurotoxin when bound to the 900 kDn complex. ..
- MOLECULAR STRUCTURE OF THE 900 KD BOTULINUM NEUROTOXIN COMPLEXRAYMOND STEVENS; Fiscal Year: 2000..We will crystallize the 900 kDa complex in the presence of scFv antibody molecules that have a high affinity for exposed regions of the neurotoxin when bound to the 900 kDn complex. ..
- MOLECULAR STRUCTURE OF THE 900 KD BOTULINUM NEUROTOXIN COMPLEXRAYMOND STEVENS; Fiscal Year: 2001
- MOLECULAR STRUCTURE OF THE 900 KD BOTULINUM NEUROTOXIN COMPLEXRAYMOND STEVENS; Fiscal Year: 2001
- MOLECULAR STRUCTURE OF THE 900 KD BOTULINUM NEUROTOXIN COMPLEXRAYMOND STEVENS; Fiscal Year: 2002
- MOLECULAR STRUCTURE OF THE 900 KD BOTULINUM NEUROTOXIN COMPLEXRAYMOND STEVENS; Fiscal Year: 1999
- Ear Canal Optical Coherent Tomography SystemPAUL SHNITSER; Fiscal Year: 2010..The ECOCT technology will reduce the hearing aid cost (by decreasing the rework to get a better fit), and improve the sound quality, convenience, and comfort of hearing aid use. ..
- FULLY THREE-DIMENSIONAL TOMOGRAPHY MEETINGGRANT GULLBERG; Fiscal Year: 1993....
- A New Integrated Endoscope SystemLih Y Lin; Fiscal Year: 2010..PHS 398/2590 (Rev. 09/04, Reissued 4/2006) Page 1 Continuation Format Page ..
- A New Integrated Endoscope SystemLIH LIN; Fiscal Year: 2009..PHS 398/2590 (Rev. 09/04, Reissued 4/2006) Page 1 Continuation Format Page ..
- Three-Dimensional Imaging of Whole Cells by Using X-ray Diffraction MicroscopyJianwei Miao; Fiscal Year: 2010..This novel imaging technique will be applied to the localization of multiprotein complexes inside whole cells. ..
- Three-Dimensional Imaging of Whole Cells by Using X-ray Diffraction MicroscopyJianwei Miao; Fiscal Year: 2009..This novel imaging technique will be applied to the localization of multiprotein complexes inside whole cells. ..
- Multiphoton Fluorescence Lifetime Imaging of Solid Tumors InvivoV Krishnan Ramanujan; Fiscal Year: 2009..These findings will pave a way for monitoring the real-time effects of pharmacological intervention on reducing tumor burden in vivo. ..
- Multiphoton Fluorescence Lifetime Imaging of Solid Tumors InvivoV Krishnan Ramanujan; Fiscal Year: 2010..These findings will pave a way for monitoring the real-time effects of pharmacological intervention on reducing tumor burden in vivo. ..
- High Resolution 3D Optics Coherence Phase MicroscopyJohannes F de Boer; Fiscal Year: 2010..OCPM will serve as a powerful imaging tool for processes in cell biology and will enhance the understanding of the structure, function, and the behavior of living cells. ..
- High Resolution 3D Optics Coherence Phase MicroscopyJohannes De Boer; Fiscal Year: 2009..OCPM will serve as a powerful imaging tool for processes in cell biology and will enhance the understanding of the structure, function, and the behavior of living cells. ..
- Posterior glenohumeral capsule influence on shoulder impingementJOHN BORSTAD; Fiscal Year: 2009..The findings of this research are likely to improve shoulder rehabilitation, decrease patient impairment and disability, prevent impingement, and lower health care costs. ..
- Posterior glenohumeral capsule influence on shoulder impingementJOHN DAVID BORSTAD; Fiscal Year: 2010..The findings of this research are likely to improve shoulder rehabilitation, decrease patient impairment and disability, prevent impingement, and lower health care costs. ..
- Posterior glenohumeral capsule influence on shoulder impingementJOHN BORSTAD; Fiscal Year: 2007..The findings of this research are likely to improve shoulder rehabilitation, decrease patient impairment and disability, prevent impingement, and lower health care costs. ..
- EM STUDIES ON MUSCLEKENNETH ALLEN TAYLOR; Fiscal Year: 2011..The molecular basis of stretch activation is unknown. Stretch activation is critical to flight by certain genera of insects making them an excellent model system with which to investigate this phenomenon. ..
- THREE DIMENSIONAL STRUCTURE OF ALPHA ACTININKenneth Taylor; Fiscal Year: 2000..5) Determine conditions that will both produce crystals of one or more alpha-actinin isoforms of a size suitable for an atomic structure analysis and preserve their crystalline order in the electron microscope. ..
- THREE DIMENSIONAL STRUCTURE OF ALPHA ACTININKenneth Taylor; Fiscal Year: 1999..5) Determine conditions that will both produce crystals of one or more alpha-actinin isoforms of a size suitable for an atomic structure analysis and preserve their crystalline order in the electron microscope. ..
- DEVELOPING VIRTUAL COLONOSCOPY FOR CANCER SCREENINGJEROME LIANG; Fiscal Year: 2006..unreadable] [unreadable]..
- DEVELOPING VIRTUAL COLONOSCOPY FOR CANCER SCREENINGJEROME LIANG; Fiscal Year: 2005....
- DEVELOPING VIRTUAL COLONOSCOPY FOR CANCER SCREENINGJEROME LIANG; Fiscal Year: 2007..unreadable] [unreadable]..
- STRUCTURAL STUDIES OF BACTERIAL FLAGELLADavid Derosier; Fiscal Year: 1990..It has been suggested that this structure is an important element of the motor. Freeze-fracture, deep-etch, shadowed replicas of Aquaspirillum serpens and Salmonella typhimurium will be used to visualize the structure...
- STRUCTURAL STUDIES OF BACTERIAL FLAGELLADavid Derosier; Fiscal Year: 1999..It has been suggested that this structure is an important element of the motor. Freeze-fracture, deep-etch, shadowed replicas of Aquaspirillum serpens and Salmonella typhimurium will be used to visualize the structure. ..
- Structural Studies of Alphavirus Membrane Fusion In SituWei Zhang; Fiscal Year: 2009..Knowledge gained from such studies provides potential targets for anti-viral reagents. ..
- Structural Studies of Alphavirus Membrane Fusion In SituWei Zhang; Fiscal Year: 2010..Knowledge gained from such studies provides potential targets for anti-viral reagents. ..
- 3-D Imaging Technique for Applications in AnthropomePEISEN HUANG; Fiscal Year: 2001..The effectiveness of lung volume reduction surgery (LVRS) will be evaluated. The technique developed in this research should have numerous other medical as well as engineering applications. ..
- A MULTI-SCALE APPROACH TO CELL STRUCTURE & FUNCTIONAndreas Hoenger; Fiscal Year: 2009..The data we will obtain will constitute an essential understanding of cellular processes that may lead to new cures and treatments of many diseases. ..
- Optimized whole-lung mapping of the oxygen concentration in human lungs, using HyIULIAN CONSTANTIN RUSET; Fiscal Year: 2010....
- Focal Structure-Function Relationships in Macular Layers from 3D Spectral OCTMILAN contact SONKA; Fiscal Year: 2010..This study has potentially important consequences for glaucoma, anterior ischemic neural neuropathy, and other retinal disease diagnosis and treatment. ..
- 3-D Imaging Technique for Applications in AnthropomePEISEN HUANG; Fiscal Year: 2002..The effectiveness of lung volume reduction surgery (LVRS) will be evaluated. The technique developed in this research should have numerous other medical as well as engineering applications. ..
- A MULTI-SCALE APPROACH TO CELL STRUCTURE & FUNCTIONAndreas Hoenger; Fiscal Year: 2010..The data we will obtain will constitute an essential understanding of cellular processes that may lead to new cures and treatments of many diseases. ..
- Focal Structure-Function Relationships in Macular Layers from 3D Spectral OCTMilan Sonka; Fiscal Year: 2009..This study has potentially important consequences for glaucoma, anterior ischemic neural neuropathy, and other retinal disease diagnosis and treatment. ..
- A MULTI-SCALE APPROACH TO CELL STRUCTURE & FUNCTIONAndreas Hoenger; Fiscal Year: 2010..The data we will obtain will constitute an essential understanding of cellular processes that may lead to new cures and treatments of many diseases. ..
- High Resolution Multiplexed Fluorescence TomographyMARK JONATHAN NIEDRE; Fiscal Year: 2010..We anticipate that the scanner will have many applications in biomedical research including studying disease development and response to novel therapeutics in vivo. ..
- High-Content Image Analysis of Global DNA Methylation Patterns for Drug ScreeningArkadiusz Gertych; Fiscal Year: 2010..Automatic analysis and quantification of global DNA methylation patterns in individual cells allows the evaluation of drug response and treatment effects. ..
- BENIGN PROSTATIC HYPERPLASIA AND PROSTATITISTHOMAS PRETLOW; Fiscal Year: 1992..We shall investigate these and other markers to define differences that distinguish these entities from each other and to better understand the biological potentials of these entities...
- A SonoKnife for Advanced CancersEduardo Moros; Fiscal Year: 2009..We called this new technology the SonoKnife, a scanned, line-focused ultrasound thermal therapy system specifically designed for non-invasive thermal ablation. ..
- Biomechanics of Spine FractureTONY KEAVENY; Fiscal Year: 2007..abstract_text> ..
- Biomechanics of Spine FractureTONY KEAVENY; Fiscal Year: 2005..abstract_text> ..
- Biomechanics of Spine FractureTONY KEAVENY; Fiscal Year: 2004..abstract_text> ..
- Biomechanics of Spine FractureTONY KEAVENY; Fiscal Year: 2006..abstract_text> ..
- Image mapped spectroscopy for snapshot 3-D biomedical imagingMark Pierce; Fiscal Year: 2011..We anticipate that this capability will improve the yield of biopsy collection in screening situations, and provide diagnostic information at locations where tissue could not otherwise be removed. ..
- Image Reconstruction Algorithms for Optical TomographyJOHN SCHOTLAND; Fiscal Year: 2009..We will utilize the parallel plate imaging geometry which is often employed in optical mammography. The results of this research are expected to impact the design of clinically useful instruments for noncontact optical tomography. ..
- Image Reconstruction Algorithms for Optical TomographyJOHN SCHOTLAND; Fiscal Year: 2007..We will utilize the parallel plate imaging geometry which is often employed in optical mammography. The results of this research are expected to impact the design of clinically useful instruments for noncontact optical tomography. ..
- 3-D ANALYSIS OF LEFT VENTRIULAR REGIONAL WALL MOTIONR Clark; Fiscal Year: 1990....
- HERPESVIRAL ONCOGENESIS, LATENCY AND REACTIVATIONNancy Raab Traub; Fiscal Year: 1999..Overall, the program project will continue to dissect the viral/cellular molecular interactions that occur during viral infection and determine how specific molecular events underlie herpes virus pathogenesis. ..
- HERPESVIRAL ONCOGENESIS, LATENCY AND REACTIVATIONNancy Raab Traub; Fiscal Year: 2003..Overall, the program project will continue to dissect the viral/cellular molecular interactions that occur during viral infection and determine how specific molecular events underlie herpes virus pathogenesis. ..
- HERPESVIRAL ONCOGENESIS, LATENCY AND REACTIVATIONNancy Raab Traub; Fiscal Year: 2000..Overall, the program project will continue to dissect the viral/cellular molecular interactions that occur during viral infection and determine how specific molecular events underlie herpes virus pathogenesis. ..
- HERPESVIRAL ONCOGENESIS, LATENCY AND REACTIVATIONNancy Raab Traub; Fiscal Year: 2004
- HERPESVIRAL ONCOGENESIS, LATENCY AND REACTIVATIONNancy Raab Traub; Fiscal Year: 2001
- HERPESVIRAL ONCOGENESIS, LATENCY AND REACTIVATIONNancy Raab Traub; Fiscal Year: 2002
- BIO-RAD CONFOCAL MICROSCOPE & 3-D ANALYSIS WORK STATIONTheresa Harrison; Fiscal Year: 1991..Thomas Rosenquist, who is conducting research at a confocal facility at Univ. of South Carolina, will provide expertise and assistance to the other users and technical support in setting up the facility...
- C-Arm CT for Guidence of Cardiac InterventionsRebecca Fahrig; Fiscal Year: 2009..Access to such images, during an interventional procedure, could also enable new, directed treatments for myocardial infarction by allowing accurate guidance of therapy (cell, drug etc.) directly to the affected tissue. ..
- 3D Imaging of electrical activity in myocardial tissueArkady Pertsov; Fiscal Year: 2004..Successful completion of this project will break ground for a new technology, the 3D imaging of electrical activation in the heart. ..
- 3D Imaging of electrical activity in myocardial tissueArkady Pertsov; Fiscal Year: 2005..Successful completion of this project will break ground for a new technology, the 3D imaging of electrical activation in the heart. ..
- 3D Imaging of electrical activity in myocardial tissueArkady Pertsov; Fiscal Year: 2003..Successful completion of this project will break ground for a new technology, the 3D imaging of electrical activation in the heart. ..
- 3D Imaging of electrical activity in myocardial tissueArkady Pertsov; Fiscal Year: 2006
- VIRUS ASSEMBLY AND PROTEIN ADAPTABILITYDONALD CASPAR; Fiscal Year: 1999....
- VIRUS ASSEMBLY AND PROTEIN ADAPTABILITYDONALD CASPAR; Fiscal Year: 2000....
- MEDICAL IMAGE SEGMENTATION USING KNOWLEDGE OF ANATOMYJames Brinkley; Fiscal Year: 1992..Because of the fundamental roles that anatomy and structural biology play within the medical sciences, such a knowledge base will have wide applicability in clinical medicine, teaching and basic research...
- An Electron Microscope for the study of Complex Biological AssembliesMICHAEL ROSSMANN; Fiscal Year: 2006..The instrument would also allow us to perform tomographic studies at about 50 A resolution on pleomorphic viruses and cell organelles that lack structural homogeneity. [unreadable] [unreadable] [unreadable]..
- Ophthalmic Imaging Using Adaptive Optics and OCTJohn Werner; Fiscal Year: 2003The purpose of this BRP is to develop and evaluate new instrumentation that will permit unprecedented three dimensional imaging of single cells in the human retina, specifically rod and cone photoreceptors and ganglion cells...
- LOW-MOLECULAR WEIGHT LIGANDS FOR PROSTATE CANCERJOHN FRANGIONI; Fiscal Year: 2002..We believe that prostate- specific, low-molecular weight ligands will someday be clinically useful reagents for improved prostate cancer detection and guided therapy. ..
- LOW-MOLECULAR WEIGHT LIGANDS FOR PROSTATE CANCERJOHN FRANGIONI; Fiscal Year: 2003..We believe that prostate- specific, low-molecular weight ligands will someday be clinically useful reagents for improved prostate cancer detection and guided therapy. ..
- Ophthalmic Imaging Using Adaptive Optics and OCTJohn Werner; Fiscal Year: 2004The purpose of this BRP is to develop and evaluate new instrumentation that will permit unprecedented three dimensional imaging of single cells in the human retina, specifically rod and cone photoreceptors and ganglion cells...
- LOW-MOLECULAR WEIGHT LIGANDS FOR PROSTATE CANCERJOHN FRANGIONI; Fiscal Year: 2000..We believe that prostate- specific, low-molecular weight ligands will someday be clinically useful reagents for improved prostate cancer detection and guided therapy. ..
- Ophthalmic Imaging Using Adaptive Optics and OCTJohn Werner; Fiscal Year: 2006The purpose of this BRP is to develop and evaluate new instrumentation that will permit unprecedented three dimensional imaging of single cells in the human retina, specifically rod and cone photoreceptors and ganglion cells...
- Ophthalmic Imaging Using Adaptive Optics and OCTJohn Werner; Fiscal Year: 2007
- Intra-operative specimen tomosynthesis for margin assessment in breast surgeryEMRE TOKER; Fiscal Year: 2009..system could also serve as a realistic test bed for assessing the clinical efficacy of tomosynthesis in three dimensional imaging of breast tissue, in anticipation of full-breast screening tomosynthesis systems currently under ..