human body

Summary

Summary: The human being as a non-anatomical and non-zoological entity. The emphasis is on the philosophical or artistic treatment of the human being, and includes lay and social attitudes toward the body in history. (From J. Cassedy, NLM History of Medicine Division)

Top Publications

  1. pmc Dynamics and associations of microbial community types across the human body
    Tao Ding
    Department of Microbiology and Immunology, 1500 W Medical Center, University of Michigan, Ann Arbor, Michigan 48109, USA
    Nature 509:357-60. 2014
  2. pmc Estimating three-dimensional orientation of human body parts by inertial/magnetic sensing
    Angelo Maria Sabatini
    The BioRobotics Institute, Scuola Superiore Sant Anna, Piazza Martiri della Libertà 33, 56124 Pisa, Italy
    Sensors (Basel) 11:1489-525. 2011
  3. pmc Touching a rubber hand: feeling of body ownership is associated with activity in multisensory brain areas
    H Henrik Ehrsson
    Wellcome Department of Cognitive Neurology, Institute of Neurology, London WC1N 3BG, United Kingdom
    J Neurosci 25:10564-73. 2005
  4. ncbi A cortical area selective for visual processing of the human body
    P E Downing
    School of Psychology, Centre for Cognitive Neuroscience, University of Wales, Bangor LL57 2AS, UK
    Science 293:2470-3. 2001
  5. doi Interaction of MRI field gradients with the human body
    P M Glover
    The Sir Peter Mansfield Magnetic Resonance Centre, School of Physics and Astronomy, University of Nottingham, Nottingham, UK
    Phys Med Biol 54:R99-R115. 2009
  6. doi A comprehensive survey of Wireless Body Area Networks : on PHY, MAC, and Network layers solutions
    Sana Ullah
    UWB ITRC Research Center, Inha University, Nam gu Incheon, South Korea
    J Med Syst 36:1065-94. 2012
  7. pmc From preferred to actual mate characteristics: the case of human body shape
    Alexandre Courtiol
    CNRS Institut des Sciences de l Evolution, Universite Montpellier 2, Montpellier, France
    PLoS ONE 5:e13010. 2010
  8. doi Methods of human body odor sampling: the effect of freezing
    Pavlina Lenochova
    Department of Anthropology, Faculty of Humanities, Charles University, Husnikova 2075, 158 00 Prague 13, Czech Republic
    Chem Senses 34:127-38. 2009
  9. doi Children's human figure drawings do not measure intellectual ability
    Emma Willcock
    Department of Psychology, University of Otago, Dunedin 9054, New Zealand
    J Exp Child Psychol 110:444-52. 2011
  10. doi Emotional modulation of visual and motor areas by dynamic body expressions of anger
    Swann Pichon
    LPPA, CNRS College de France, Paris, France
    Soc Neurosci 3:199-212. 2008

Detail Information

Publications276 found, 100 shown here

  1. pmc Dynamics and associations of microbial community types across the human body
    Tao Ding
    Department of Microbiology and Immunology, 1500 W Medical Center, University of Michigan, Ann Arbor, Michigan 48109, USA
    Nature 509:357-60. 2014
    ..HMP) was to provide a reference collection of 16S ribosomal RNA gene sequences collected from sites across the human body that would allow microbiologists to better associate changes in the microbiome with changes in health...
  2. pmc Estimating three-dimensional orientation of human body parts by inertial/magnetic sensing
    Angelo Maria Sabatini
    The BioRobotics Institute, Scuola Superiore Sant Anna, Piazza Martiri della Libertà 33, 56124 Pisa, Italy
    Sensors (Basel) 11:1489-525. 2011
    ..robotics, virtual reality, where they can also be applied for real-time tracking of the orientation of human body parts in the three-dimensional (3D) space...
  3. pmc Touching a rubber hand: feeling of body ownership is associated with activity in multisensory brain areas
    H Henrik Ehrsson
    Wellcome Department of Cognitive Neurology, Institute of Neurology, London WC1N 3BG, United Kingdom
    J Neurosci 25:10564-73. 2005
    ..We propose that this could be the mechanism for the feeling of body ownership...
  4. ncbi A cortical area selective for visual processing of the human body
    P E Downing
    School of Psychology, Centre for Cognitive Neuroscience, University of Wales, Bangor LL57 2AS, UK
    Science 293:2470-3. 2001
    ..to faces, few studies have considered the cortical representation of the appearance of the rest of the human body. We present a series of functional magnetic resonance imaging (fMRI) studies revealing substantial evidence for ..
  5. doi Interaction of MRI field gradients with the human body
    P M Glover
    The Sir Peter Mansfield Magnetic Resonance Centre, School of Physics and Astronomy, University of Nottingham, Nottingham, UK
    Phys Med Biol 54:R99-R115. 2009
    ..The experimental measurements, and analytic and computational modelling work in this area are reviewed. The review concludes with a discussion of current regulation in this area and current practice as both are applied to MRI...
  6. doi A comprehensive survey of Wireless Body Area Networks : on PHY, MAC, and Network layers solutions
    Sana Ullah
    UWB ITRC Research Center, Inha University, Nam gu Incheon, South Korea
    J Med Syst 36:1065-94. 2012
    ..collection of low-power, miniaturized, invasive/non-invasive lightweight wireless sensor nodes that monitor the human body functions and the surrounding environment...
  7. pmc From preferred to actual mate characteristics: the case of human body shape
    Alexandre Courtiol
    CNRS Institut des Sciences de l Evolution, Universite Montpellier 2, Montpellier, France
    PLoS ONE 5:e13010. 2010
    ....
  8. doi Methods of human body odor sampling: the effect of freezing
    Pavlina Lenochova
    Department of Anthropology, Faculty of Humanities, Charles University, Husnikova 2075, 158 00 Prague 13, Czech Republic
    Chem Senses 34:127-38. 2009
    ..Again no differences in subjective ratings were observed. These results suggest that freezing has no significant effect on perceived odor hedonicity and that samples can be reliably used after storage for relatively long periods...
  9. doi Children's human figure drawings do not measure intellectual ability
    Emma Willcock
    Department of Psychology, University of Otago, Dunedin 9054, New Zealand
    J Exp Child Psychol 110:444-52. 2011
    ..We conclude that the DAP:QSS is not a valid measure of intellectual ability and should not be used as a screening tool...
  10. doi Emotional modulation of visual and motor areas by dynamic body expressions of anger
    Swann Pichon
    LPPA, CNRS College de France, Paris, France
    Soc Neurosci 3:199-212. 2008
    ....
  11. doi Statistical multi-path exposure method for assessing the whole-body SAR in a heterogeneous human body model in a realistic environment
    Günter Vermeeren
    Department of Information Technology, Ghent University Interdisciplinary Institute for Broadband Technology IBBT, Ghent, Belgium
    Bioelectromagnetics 34:240-51. 2013
    ..This article describes the development of a statistical multi-path exposure method for heterogeneous realistic human body models...
  12. ncbi Selectivity for the human body in the fusiform gyrus
    Marius V Peelen
    School of Psychology, Centre for Cognitive Neuroscience, University of Wales, Bangor, United Kingdom LL57 2AS
    J Neurophysiol 93:603-8. 2005
    ..These results challenge accounts of the mid-fusiform gyrus that focus solely on faces and suggest that this region contains multiple distinct category-selective neural representations...
  13. ncbi The neural correlates of perceiving human bodies: an ERP study on the body-inversion effect
    Jeroen J Stekelenburg
    Psychonomics Laboratory, Tilburg University, P O Box 90153, 5000 LE Tilburg, The Netherlands
    Neuroreport 15:777-80. 2004
    ..Our results indicate that, like faces, bodies are processed configurally, and that within each category qualitative differences are observed for emotional as opposed to neutral images...
  14. ncbi Structural encoding of body and face in human infants and adults
    Teodora Gliga
    CNRS, Unité INSERM 562, Service Hospitalier Frederic Joliot, CEA DRM DSV, Orsay, France
    J Cogn Neurosci 17:1328-40. 2005
    ..This could either be related to an innate knowledge of this particular type of biological object, or to fast learning through intense exposure during the first months of life...
  15. pmc The naked truth: the face and body sensitive N170 response is enhanced for nude bodies
    Jari K Hietanen
    Human Information Processing Laboratory, School of Social Sciences and Humanities, University of Tampere, Tampere, Finland
    PLoS ONE 6:e24408. 2011
    ..Such facilitated visual processing of other people's nude bodies is possibly beneficial in identifying potential mating partners and competitors, and for triggering sexual behavior...
  16. ncbi Functional MRI analysis of body and body part representations in the extrastriate and fusiform body areas
    John C Taylor
    School of Psychology, Adeilad Brigantia, Penrallt Road, Bangor, UK LL57 2AS
    J Neurophysiol 98:1626-33. 2007
    ..Specifically, we hypothesize that the EBA analyzes bodies at the level of parts (as has been proposed for faces in the OFA), whereas FBA (by analogy to FFA) may have a role in processing the configuration of body parts into wholes...
  17. ncbi An event-related potential component sensitive to images of the human body
    Guillaume Thierry
    School of Psychology, University of Wales, Bangor, Gwynedd LL57 2AS, UK
    Neuroimage 32:871-9. 2006
    ..In Experiment 1, a comparison of ERPs elicited by faces, bodies, objects and places showed that pictures of the human body (without the head) elicit a negative component peaking at 190 ms (an N190)...
  18. ncbi Magnetic stimulation of extrastriate body area impairs visual processing of nonfacial body parts
    Cosimo Urgesi
    Dipartimento di Scienze Neurologiche e della Visione, Sezione di Fisiologia, Universita degli Studi di Verona, Strada Le Grazie 8, I 37134 Verona, Italy
    Curr Biol 14:2130-4. 2004
    Functional magnetic resonance imaging indicates that observation of the human body induces a selective activation of a lateral occipitotemporal cortical area called extrastriate body area (EBA)...
  19. ncbi Separate face and body selectivity on the fusiform gyrus
    Rebecca F Schwarzlose
    Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA
    J Neurosci 25:11055-9. 2005
    ..These results demonstrate strong selectivities in distinct but adjacent regions in the fusiform gyrus for only faces in one region (the FFA*) and only bodies in the other (the FBA*)...
  20. ncbi Representation of body identity and body actions in extrastriate body area and ventral premotor cortex
    Cosimo Urgesi
    Istituto di Ricovero e Cura a Carattere Scientifico E Medea, Polo Regionale Friuli Venezia Giulia, I 33078, San Vito al Tagliamento, Pordenone, Italy
    Nat Neurosci 10:30-1. 2007
    ..This double dissociation suggests that whereas extrastriate body area mainly processes actors' body identity, premotor cortex is crucial for visual discriminations of actions...
  21. ncbi Perceptual adaptation affects attractiveness of female bodies
    Christopher Winkler
    School of Psychology, University of Western Australia, Australia
    Br J Psychol 96:141-54. 2005
    ..Substantial changes in what looked normal were accompanied by congruent changes in what looked attractive, suggesting that a normal or average body shape may function as a reference point against which body attractiveness is judged...
  22. pmc Why the way we consider the body matters - reflections on four bioethical perspectives on the human body
    Silke Schicktanz
    University of Gottingen, Dept of Medical Ethics and History of Medicine, Humboldtallee 36, 37073 Gottingen, Germany
    Philos Ethics Humanit Med 2:30. 2007
    Within the context of applied bioethical reasoning, various conceptions of the human body are focused upon by the author in relation to normative notions of autonomy.
  23. ncbi Evidence for multiple, distinct representations of the human body
    John Schwoebel
    Cabrini College, Radnor, PA, USA
    J Cogn Neurosci 17:543-53. 2005
    ..studies have suggested distinctions among structural, conceptual, and online sensorimotor representations of the human body. We developed a battery of tasks to further examine the prevalence and anatomic substrates of these body ..
  24. pmc Psychologically induced cooling of a specific body part caused by the illusory ownership of an artificial counterpart
    G Lorimer Moseley
    Department of Physiology, Anatomy and Genetics, Oxford University, Oxford OX1 3QX, United Kingdom
    Proc Natl Acad Sci U S A 105:13169-73. 2008
    ....
  25. ncbi Human body scents: conscious perceptions and biological effects
    Martha K McClintock
    Department of Psychology, University of Chicago, 5730 Woodlawn Ave, Chicago, IL 60637, USA
    Chem Senses 30:i135-7. 2005
  26. doi Public moralities concerning donation and disposition of organs: results from a cross-European study
    Mark Schweda
    Department of Medical Ethics and History of Medicine at the University of Göttingen, Gottingen, Germany
    Camb Q Healthc Ethics 17:308-17. 2008
  27. pmc An alternative to the cosmic and mechanic metaphors for the human body? The house illustration in Ma'aseh Tuviyah (1708)
    Etienne Lepicard
    Sackler School of Medicine, Tel Aviv University, Israel
    Med Hist 52:93-105. 2008
  28. ncbi Investigating the validity of the Draw-A-Person: Screening Procedure for Emotional Disturbance: a measurement validation study with high-risk youth
    Holly C Matto
    School of Social Work, Virginia Commonwealth University, 3330 Washington Boulevard, Suite 400, Arlington, Virginia 22201, USA
    Psychol Assess 14:221-5. 2002
    ..Findings lend preliminary support to the DAP:SPED's validity in providing assessment information about child behavioral functioning. Continued validation investigation along these lines is recommended...
  29. ncbi What does it mean to use someone as "a means only": rereading Kant
    R M Green
    Ethics Institute, Dartmouth College, Hanover, NH
    Kennedy Inst Ethics J 11:247-61. 2001
    ..Only the third of these interpretations, I conclude, offers a reasonable and coherent approach to moral judgment about the limits of commodification...
  30. pmc Signal transmission in a human body medium-based body sensor network using a Mach-Zehnder electro-optical sensor
    Yong Song
    School of Opto electronic, Beijing Institute of Technology, Beijing 100081, China
    Sensors (Basel) 12:16557-70. 2012
    The signal transmission technology based on the human body medium offers significant advantages in Body Sensor Networks (BSNs) used for healthcare and the other related fields...
  31. doi Neural correlates of human body perception
    Rosanne Aleong
    Montreal Neurological Institute, McGill University
    J Cogn Neurosci 22:482-95. 2010
    ..novel in that they address potential sex differences in the lateralization of EBA and FBA responses to human body images...
  32. ncbi The role of human body movements in mate selection
    Nadine Hugill
    Department of Sociobiology Anthropology, Institute of Zoology and Anthropology, University of Gottingen, Gottingen, Germany
    Evol Psychol 8:66-89. 2010
    ....
  33. pmc Dynamic propagation channel characterization and modeling for human body communication
    Zedong Nie
    Shenzhen Institutes of Advanced Technology, Chinese Academy of Science, Shenzhen 518055, China
    Sensors (Basel) 12:17569-87. 2012
    This paper presents the first characterization and modeling of dynamic propagation channels for human body communication (HBC). In-situ experiments were performed using customized transceivers in an anechoic chamber...
  34. doi Losing your head: behavioral and electrophysiological effects of body inversion
    Denise A Minnebusch
    Ruhr University of Bochum, Germany
    J Cogn Neurosci 21:865-74. 2009
    The present study aimed to further explore the mechanisms underlying the perception of human body shapes...
  35. ncbi Bodily systems and the spatial-functional structure of the human body
    Barry Smith
    Institute for Formal Ontology and Medical Information Science, Faculty of Medicine, University of Leipzig, Leipzig, Germany
    Stud Health Technol Inform 102:39-63. 2004
    The human body is a system made of systems...
  36. ncbi Bare hands and attention: evidence for a tactile representation of the human body
    H Branch Coslett
    Department of Neurology and Center for Cognitive Neuroscience, University of Pennsylvania, 3400 Spruce St, Philadelphia, PA 19104, USA
    Neuropsychologia 42:1865-76. 2004
    ..These data demonstrate that the hand may serve as a conduit for attention and provide strong evidence for a distinct representation of the body surface that is at least in part independent of spatial representations...
  37. pmc The Human Tissue Act (2004), anatomical examination and the importance of body donation in Northern Ireland
    Samantha J Taylor
    Division of Basic Medical Sciences Anatomy, School of Medicine and Dentistry, The Queen s University of Belfast, Whitla Medical Building, 97 Lisburn Road, Belfast BT9 7BL, United Kingdom
    Ulster Med J 76:124-6. 2007
  38. doi Height and body mass influence on human body outlines: a quantitative approach using an elliptic Fourier analysis
    Alexandre Courtiol
    Universite Montpellier 2, CNRS, Institut des Sciences de l Evolution, Equipe Génétique de l Adaptation, C C 065, 34095 Montpellier Cedex 05, France
    Am J Phys Anthropol 142:22-9. 2010
    Many studies use representations of human body outlines to study how individual characteristics, such as height and body mass, affect perception of body shape. These typically involve reality-based stimuli (e.g...
  39. ncbi Commodification arguments for the legal prohibition of organ sale
    S Wilkinson
    Department of Philosophy, Keele University, Staffordshire, UK
    Health Care Anal 8:189-201. 2000
    ..Secondly, in the light of this analysis, the claim that organ sale involves commodifying the human body is examined...
  40. ncbi HealthCyberMap: a semantic visual browser of medical Internet resources based on clinical codes and the human body metaphor
    Maged N Kamel Boulos
    Centre for Measurement and Information in Medicine, School of Informatics, City University, London, UK
    Health Info Libr J 19:189-200. 2002
    ....
  41. ncbi The commodification of the body and its parts
    L A Sharp
    Department of Anthropology, Barnard College, New York, NY 10027, USA
    Annu Rev Anthropol 29:287-328. 2000
    The human body--and its parts--has long been a target for commodification within myriad cultural settings...
  42. ncbi Dystopian anxieties versus utopian ideals: medicine from Frankenstein to The Visible Human Project and Body Worlds
    Megan Stern
    SALS, London Metropolitan University, 166 220 Holloway Road, London N7, UK
    Sci Cult (Lond) 15:61-84. 2006
  43. ncbi [Biomedical research practice and therapeutic practice: to whom does the human body belong?]
    Marie Gaille-Nikodimov
    CERSES, IRESCO, 59 61, rue Pouchet, 75849 Paris Cedex 17, France
    Med Sci (Paris) 22:214-7. 2006
    Who owns the human body? This issue has been formerly raised about the status of the slave. Today, it has become a prominent stake for when reflecting on biomedical research and healthcare practices...
  44. ncbi The social life of genes: privacy, property and the new genetics
    Margaret Everett
    Department of Anthropology, Portland State University, Portland, OR 97207 0751, USA
    Soc Sci Med 56:53-65. 2003
    ..The anthropological critique of the commodification of the body, and the concept of 'embodiment' are useful in analyzing the debate over DNA as property...
  45. ncbi Biotechnology and the spirit of capitalism
    Eric Cohen
    Bioethics and American Democracy program, Ethics and Public Policy Center, Washington, DC, USA
    New Atlantis 12:9-23. 2006
  46. ncbi Normative aspects of the human body
    Ludwig Siep
    Philosophisches Seminar, Westfalische Wilhelms Universitat, Munster, Germany
    J Med Philos 28:171-85. 2003
    In cultural history the human body has been the object of a great variety of opposing valuations, ranging from "imago dei" to "the devil's tool"...
  47. ncbi A functional magnetic resonance imaging study of the body schema using full human line-drawing figures in an on-line verbal naming and localization task of single body part words
    Simon M McCrea
    Department of Biomedical Engineering, Faculty of Medicine, University of Alberta, Edmonton, Alberta, Canada T6G 2V2
    Behav Brain Res 180:235-40. 2007
    ....
  48. ncbi My body or yours? The effect of visual perspective on cortical body representations
    Rebecca Saxe
    Psychology Department, Harvard University, Cambridge, MA 02139, USA
    Cereb Cortex 16:178-82. 2006
    A human body part, such as a foot, may be observed from an egocentric perspective (consistent with looking at one's own body, e.g...
  49. ncbi Is it right or is it useful? Patenting of the human gene, Lockean property rights, and the erosion of the imago Dei
    Paige Comstock Cunningham
    Americans United for Life, USA
    Ethics Med 19:85-98. 2003
  50. ncbi An introduction to legal thought: four approaches to law and to the allocation of body parts
    Guido Calabresi
    United States Court of Appeals, USA
    Stanford Law Rev 55:2113-51. 2003
  51. ncbi Parental consent and the use of dead children's bodies
    T M Wilkinson
    Department of Political Studies, University of Auckland, New Zealand
    Kennedy Inst Ethics J 11:337-58. 2001
    ..The only direct reason to get parental consent is to avoid distressing the parents, which carries implications for the consent process, secret harvesting of body parts, and the weight to be given to parental feelings...
  52. ncbi Body identification, biometrics and medicine: ethical and social considerations
    Emilio Mordini
    Centro per la Scienza, la Società e la Cittadinanza, Via Sistina 37, 00187 Rome, Italy
    Ann Ist Super Sanita 43:51-60. 2007
    ..The human body lies at the heart of all strategies for identity management...
  53. ncbi Genetics, biometrics and the informatization of the body
    Irma Van Der Ploeg
    Zuyd University, Heerlen, The Netherlands
    Ann Ist Super Sanita 43:44-50. 2007
    ..The final section will discuss some of these meta-problems...
  54. ncbi Similar facial electromyographic responses to faces, voices, and body expressions
    Maurice J C M Magnée
    Department of Child and Adolescent Psychiatry, Rudolf Magnus Institute of Neuroscience, University Medical Center, Utrecht, The Netherlands
    Neuroreport 18:369-72. 2007
    ..We suggest that seeing a facial expression, an emotional body expression or hearing an emotional tone of voice all activate the affect program corresponding to the emotion displayed...
  55. ncbi Cerebral processes in mental transformations of body parts: recognition prior to rotation
    Leila S Overney
    Macquarie Centre for Cognitive Science, Macquarie University, Sydney NSW 2109, Australia
    Brain Res Cogn Brain Res 25:722-34. 2005
    There is growing evidence that the visual processing of human body stimuli is particular and distinct from that of other objects. This is due to implicit knowledge of anatomical and biomechanical constraints of the human body...
  56. ncbi Patterns of fMRI activity dissociate overlapping functional brain areas that respond to biological motion
    Marius V Peelen
    School of Psychology, University of Wales, Bangor, Gwynedd LL57 2AS, United Kingdom
    Neuron 49:815-22. 2006
    ....
  57. ncbi An interest in human dignity as the basis for genomic torts
    Roger Brownsword
    University of Sheffield, England
    Washburn Law J 42:413-81. 2003
  58. ncbi The new French resistance: commodification rejected?
    Donna Dickenson
    Birkbeck College, University of London, UK
    Med Law Int 7:41-63. 2005
  59. doi Is it mine? Hemispheric asymmetries in corporeal self-recognition
    Francesca Frassinetti
    Department of Psychology, University of Bologna, Italy
    J Cogn Neurosci 20:1507-16. 2008
    ..These findings suggest that the right hemisphere may be involved in the recognition of self body parts, through a fronto-parietal network...
  60. ncbi Biotechnology and the new right: neoconservatism's red menace
    Jonathan D Moreno
    Center for American Progress, Washington, DC 20005, USA
    Am J Bioeth 7:7-13. 2007
    ..By not acknowledging and embracing their intellectual roots, neoconservatives are left with a deeply ambivalent and often confused view of biotechnology and the society that gives rise to it...
  61. ncbi Consent, commodification and benefit-sharing in genetic research
    Donna Dickenson
    Dev World Bioeth 4:109-24. 2004
    ..However, they also highlight the continued tension about what is really wrong with commodifying human tissue or the human genome. Where's the injustice, and can it be solved by a more sophisticated consent procedure?..
  62. ncbi Bodyworlds and the ethics of using human remains: a preliminary discussion
    Y Michael Barilan
    Dep Medicine B, Meir Hospital, Kfar Saba, Israel
    Bioethics 20:233-47. 2006
    ..In the case of live donations, Bodyworlds has a duty to participate in the medical care of needy donors. However, secrecy with regard to the source of cadavers seems to be the most troublesome aspect of Bodyworlds...
  63. ncbi Contested bodies: property models and the commodification of human biological artefacts
    Bronwyn Parry
    Department of Geography, Queen Mary University of London, Mile End Road, London E1 4NS, UK
    Sci Cult (Lond) 15:139-58. 2006
  64. ncbi Toward a just model of alienability of human tissue
    Brian Budds
    University of San Francisco Law School, USA
    Univ San Francisco Law Rev 37:757-82. 2003
  65. ncbi Human property: threat or saviour?
    Richard Taylor
    Newcastle University Faculty of Law
    E Law 9:E4. 2002
  66. ncbi Ownership rights and the body
    Gideon Calder
    University of Wales, Newport, United Kingdom
    Camb Q Healthc Ethics 15:89-100. 2006
  67. ncbi My body, your body, our bodies
    Jonathan Herring
    Med Law Rev 15:34-61. 2007
  68. pmc Bodily rights and property rights
    B Bjorkman
    Philosophy Unit, Royal Institute of Technology, Teknikringen 78, 100 44, Stockholm, Sweden
    J Med Ethics 32:209-14. 2006
    ..We suggest five principles of bodily rights and show how they can be applied to the construction of ethically appropriate bundles of rights to biological material...
  69. ncbi Genes and spleens: property, contract, or privacy rights in the human body?
    Radhika Rao
    University of California, Hastings School of Law, USA
    J Law Med Ethics 35:371-82. 2007
    This article compares three frameworks for legal regulation of the human body. Property law systematically favors those who use the body to create commercial products...
  70. ncbi Biospecimen "ownership": point
    Roberta B Ness
    University of Pittsburg, Graduate School of Public Health, Room A548 Crabtree Hall, 130 DeSoto Street, Pittsburg, PA 15261, USA
    Cancer Epidemiol Biomarkers Prev 16:188-9. 2007
  71. ncbi The neural basis of imitation is body part specific
    Georg Goldenberg
    Neuropsychological Department, Bogenhausen Hospital, D 81925 Munich, Germany
    J Neurosci 26:6282-7. 2006
    ..Rather, they argue for an intermediate step of processing interpolated between perception and execution of gestures as has been suggested by the mirror neuron and the body part coding hypotheses...
  72. ncbi Last rights: the ethics of research on the dead
    T M Wilkinson
    Department of Political Studies, University of Auckland Private Bag 92019, Auckland, New Zealand
    J Appl Philos 19:31-41. 2002
    ..The arguments have important implications for the ethics of (amongst others) biomedical, archaeological, anthropological, historical, and sociological research...
  73. ncbi Perceptions of science. The anatomical mission to Burma
    Michael Sappol
    History of Medicine Division, National Library of Medicine, Bethesda, MD 20894, USA
    Science 302:232-3. 2003
    ..Today, as anatomical images abound in the arts and the media, we still believe that anatomical images show us our inner reality...
  74. ncbi The body as interactive display: examining bodies in a public exhibition
    Dirk vom Lehn
    Work, Interaction and Technology Research Group, King s College London, UK
    Sociol Health Illn 28:223-51. 2006
    ..The paper concludes with a discussion of how the observations and findings from the analysis bear upon debates on Body Worlds and in the sociology of health and illness...
  75. ncbi Body inversion effect without body sense: insights from deafferentation
    Simone Bosbach
    Department of Psychology, Cognition and Action, Max Planck Institute for Human Cognitive and Brain Sciences, Munich, Germany
    Neuropsychologia 44:2950-8. 2006
    ..Because people see their own body and others' bodies frequently, humans are experts in the visual processing of human body postures...
  76. ncbi The effect of viewpoint on body representation in the extrastriate body area
    Annie W Y Chan
    School of Psychology, Centre for Cognitive Neuroscience, University of Wales, Bangor LL57 2AS, UK
    Neuroreport 15:2407-10. 2004
    ..More recent evidence points to a lateral temporal region that responds to the visual appearance of the human body (extrastriate body area or EBA)...
  77. ncbi Role of gravity-based information on the orientation and localization of the perceived body midline
    Hadrien Ceyte
    Centre de Recherches du Service de Sante des Armees, BP 87, 38702, La Tronche Cedex, France
    Exp Brain Res 176:504-9. 2007
    ..It can be suggested that the horizontal component of the vestibulo-ocular reflex (VOR) contributed to the perceived localization of the body midline, whereas its orientation was mainly influenced by tactile information...
  78. doi Drive for thinness and attention toward specific body parts in a nonclinical sample
    Johannes Hewig
    Department of Biological and Clinical Psychology, Friedrich Schiller University Jena, Am Steiger 3, Haus 1, D 07743 Jena, Germany
    Psychosom Med 70:729-36. 2008
    ..We hypothesized that participants scoring high on the drive for thinness subscale would show increased attention to body regions, which are important in the assessment of body weight and thinness like the waist, hips, legs, and arms...
  79. ncbi Considering chimeras: the confluence of genetic engineering and ethics
    Marilyn E Coors
    Natl Cathol Bioeth Q 6:75-87. 2006
  80. ncbi German intellectual history and American romanticism: spirit, nature philosophy, and the occult
    Patrick Labriola
    Yearb Ger Am Stud 37:79-90. 2002
  81. ncbi "To what purpose does it think?": dreams, sick bodies and confused minds in the Age of Reason
    Lucia Dacome
    The Wellcome Trust Centre for the History of Medicine at UCL Email
    Hist Psychiatry 15:395-416. 2004
    ..It does so by drawing attention to the body as one of the crucial sites in which changing attitudes towards dreaming were discussed and negotiated...
  82. ncbi Human nature: an oxymoron?
    David Heyd
    Department of Philosophy, The Hebrew University of Jerusalem, Israel
    J Med Philos 28:151-69. 2003
    ....
  83. ncbi [Platonic conception of a man as an element of the universe on the base of dialogue "Timajos"]
    Jacek Ziaja
    Katedra i Klinika Chirurgii Ogolnej, Katowice, Francuska
    Arch Hist Filoz Med 65:423-42. 2002
    ..In the whole lecture an attention is brought to disclosure the effect of mind in the universe and purposefulness of creator activity...
  84. ncbi [Euripides and Heraclitus on the attitude towards the corpse--an unrecognized fragment of Heraclitus in Electra, v. 289]
    Ferdinand Peter Moog
    Institut fur Geschichte und Ethik der Medizin, Universitat zu Koln
    Wurzbg Medizinhist Mitt 26:335-49. 2007
    ..Perhaps Plato's notion of the human body as the tomb of the soul is foreshadowed here. This notion may have helped demythologize the corpse...
  85. ncbi [Christian concepts related to the body, sexuality, and contraceptive practices: implications for educational work]
    Maria da Anunciação Silva
    Faculdade de Enfermagem da Universidade Federal do Mato Grosso, Brasil
    Rev Gaucha Enferm 28:459-64. 2007
    ....
  86. ncbi Japanese discussions on the concept of "person" and its function in bioethics
    Christian Steineck
    Bonn University, Institute for Research on Modern Japan, Germany
    J Int Bioethique 16:29-40, 190. 2005
    ..attempt to critically reconstruct the notion of person, integrating aspects of modern philosophy of the human body. The critical evaluation of the theories explored makes a strong case for integrating the Japanese bioethical ..
  87. ncbi Should we prevent non-therapeutic mutilation and extreme body modification?
    Thomas Schramme
    University of Wales Swansea School of Health Science, Centre for Philosophy, Humanities and Law in Health Care, UK
    Bioethics 22:8-15. 2008
    ..I find the common pathologisation of body modifications, Kant's argument of duties to oneself and the objection from irrationality all wanting. In conclusion, I see no convincing support for prohibition of voluntary mutilations...
  88. doi Ensouled bodies: the continuity of the theme of 'the body as instrument'
    Nancy van Deusen
    Claremont Graduate University, Claremont, CA, USA
    J Physiol Paris 101:280-91. 2007
    ..Further, that alternative modes of knowledge transmission exist, for example, the allegorical mode...
  89. ncbi [The discovery of the body]
    C Hipólito-Reis
    Serviço de Bioquímica, Faculdade de Medicina da Universidade do Porto, Porto
    Acta Med Port 14:497-505. 2001
    This paper initially recognises that the human body tends to implicate itself in the current triad in which it gains evidence (body, soul and spirit). Its discovery is, therefore, a difficult cognitive process...
  90. ncbi [New Croatian legislation on tissue banking]
    Mirela Busić
    Ministarstvo zdravstva i socijalne skrbi RH, Zagreb, Hrvatska
    Acta Med Croatica 61:445-7. 2007
    ..field of tissue and cell transplants is regulated by the Act of Conditions for Removal and Transplantation of Human Body Parts for Therapeutic Purposes (Official Gazette 177/04) and other decrees, which help regulating quality and ..
  91. ncbi Final report on the safety assessment of Benzyl Alcohol, Benzoic Acid, and Sodium Benzoate
    B Nair
    Cosmetic Ingredient Review Expert Panel, Washington, DC 20036, USA
    Int J Toxicol 20:23-50. 2001
    ..Benzyl Alcohol is metabolized to Benzoic Acid, which reacts with glycine and excreted as hippuric acid in the human body. Acceptable daily intakes were established by the World Health Organization at 5 mg/kg for Benzyl Alcohol, ..
  92. ncbi Mitochondria, metabolic disturbances, oxidative stress and the kynurenine system, with focus on neurodegenerative disorders
    Katalin Sas
    Department of Neurology, University of Szeged, POB 427, H 6701 Szeged, Hungary
    J Neurol Sci 257:221-39. 2007
    ..Both failure and exaggeration of apoptosis in a human body can lead to disease...
  93. ncbi [Not Available]
    A Carlino
    Istituto Universitario Europeo, Firenze
    Physis Riv Int Stor Sci 31:731-69. 1994
    ..These sheets contain a figure representing the human body (male and female) and a text describing in a concise and quite rough way the elements of the illustration...
  94. ncbi [Activity of alanine aminopeptidase in blood and in urine of smoking and non-smoking smelters]
    Anna Bizoń
    Zakład Biomedycznych Analiz Srodowiskowych, Wydział Farmaceutyczny, Akademia Medyczna, Wrocław
    Przegl Lek 67:906-9. 2010
    The human body is constantly exposed to xenobiotics. This will include exogenous substances from environmental pollution such as heavy metals and lifestyle such as smoking, which may lead to impaired functioning of many organs...
  95. doi Chromosomal aberrations and DNA damage in human populations exposed to the processing of electronics waste
    Qiang Liu
    Institute of Radiation Medicine, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin Key Laboratory of Molecular Nuclear Medicine, 238, Baidi Road, 300192, Tianjin, People s Republic of China
    Environ Sci Pollut Res Int 16:329-38. 2009
    ..not only produces enormous environmental pollution but also can bring about toxic or genotoxic effects on the human body, threatening the health of both current residents and future generations living in the local environment...
  96. doi Religious aspects of organ transplantation
    P Bruzzone
    Divisione Trapianti d Organo, Dipartimento Paride Stefanini, Universita di Roma La Sapienza, Rome, Italy
    Transplant Proc 40:1064-7. 2008
    ..Muslim ulemas (scholars) and muftis (jurists) oppose donation from human living and deceased donors because the human body is an "amanat" (trusteeship) from God and must not be desecrated following death, but they encourage ..
  97. ncbi Commensal bacteria (normal microflora), mucosal immunity and chronic inflammatory and autoimmune diseases
    Helena Tlaskalova-Hogenova
    Department of Immunology and Gnotobiology, Institute of Microbiology, Academy of Sciences of the Czech Republic, Videnska 1083, 142 20 Prague 4, Czech Republic
    Immunol Lett 93:97-108. 2004
    ..The number of bacteria colonising mucosal and skin surfaces exceeds the number of cells forming human body. Commensal bacteria co-evolved with their hosts, however, under specific conditions they are able to overcome ..
  98. ncbi The Mid-Canada Radar Line and First Nations' people of the James Bay region, Canada: an evaluation using log-linear contingency modelling to analyze organochlorine frequency data
    Leonard J S Tsuji
    Department of Environment and Resource Studies, University of Waterloo, Waterloo, Ontario, Canada N2L 3G1
    J Environ Monit 7:888-98. 2005
    ..Few data exist with respect to human body burden of organochlorines (OCs) in residents of communities located in close proximity to these radar line sites...
  99. pmc The architecture of the connective tissue in the musculoskeletal system-an often overlooked functional parameter as to proprioception in the locomotor apparatus
    Jaap van der Wal
    University Maastricht, Faculty of Health, Medicine and Life Sciences, Department of Anatomy and Embryology, Maastricht, Netherlands
    Int J Ther Massage Bodywork 2:9-23. 2009
    ..Both are instrumental in the coding of proprioceptive information to the central nervous system...
  100. ncbi Noncholesterol sterols
    Marek Vecka
    Charles University in Prague, First Faculty of Medicine, Clinical Department of Gastroenterology and Hepatology, Prague
    Acta Univ Carol Med Monogr 154:5-101. 2008
    ..The last decades changed our view to the sterol molecules on almost at all levels of their appearance in human body. In the gut, the absorption of sterols was proven to be protein dependent and the quest for the transporter was ..
  101. ncbi [Biology of essential fatty acids (EFA)]
    Jacek Dobryniewski
    Oddział III Ogólnopsychiatryczny z Pododdziałem Psychogeriatrii SPPZOZ w Choroszczy
    Przegl Lek 64:91-9. 2007
    ..EFA), are unsaturated fatty acids not produced by human being, but essential for proper functioning of the human body. To EFA-s belongs: linoleic acid (LA) (18:2,cis detla(9,12), omega6)--precursor o f gamma-linolenic acid (GLA), ..

Research Grants72

  1. STATISITICAL DESIGN, MONITORING &COORD. OF VISION CLINICAL TRIALS &EPIDEMIOLOGY
    Keri Hammel; Fiscal Year: 2013
    ..may induce oral tolerance, in which the immune system is taught to recognize and not attack normal parts of the human body. Objectives: - To evaluate the safety and effectiveness of B27PD (Optiquel(Trademark)) as a treatment for ..
  2. STATISITICAL DESIGN, MONITORING &COORD. OF VISION CLINICAL TRIALS &EPIDEMIOLOGY
    Keri Hammel; Fiscal Year: 2012
    ..may induce oral tolerance, in which the immune system is taught to recognize and not attack normal parts of the human body. Objectives: - To evaluate the safety and effectiveness of B27PD (Optiquel(Trademark)) as a treatment for ..
  3. Role of NGF in inflammatory and proliferative cascades of psoriatic disease
    Siba P Raychaudhuri; Fiscal Year: 2012
    ..NGF is a chemical mainly helps in to grow nerves in the embryo. NGF also irritates skin and other human body parts;in scientific language this is called inflammation...
  4. Vitamin D3, Interference with Androgen Signal and Inhibition of Prostate Cancer
    Bandana Chatterjee; Fiscal Year: 2013
    ..Indeed, research in recent years revealed that high vitamin D levels protect human body from many cancers, such as cancer of the colon, breast and prostate...
  5. Analysis of gene regulation of Vibrio cholerae during infection
    Jun Zhu; Fiscal Year: 2013
    ..But how, specifically, do bacterial pathogens "know" that they are in the infectious setting? The inside of the human body is a different niche world around it: in the case of the gastrointestinal tract, the oxygen tension is lower, ..
  6. Biochemistry and Function of a Novel Bacterial Photosensory Two-Component System
    MELISSA MARKS; Fiscal Year: 2010
    ..that these and other disease-causing microbes can thrive both in natural aquatic reservoirs and inside the human body. Bacterial survival across such varied environments requires robust sensory systems that can rapidly modulate ..
  7. Mucosal Memory T Cells at the Vanguard of Human Host Defense
    Donna L Farber; Fiscal Year: 2010
    The human body encounters most pathogens through mucosal sites. Two main portals are the lung and gut, where pathogens are encountered through the aerodigestive tract mucosa and oral ingestion, respectively...
  8. A new ultra-low field in-vivo EPR technology for biomedical applications
    Inseob Hahn; Fiscal Year: 2011
    ..There are several key factors, which make in vivo EPR methods of human body at high frequencies extremely difficult, the principal ones being limits on the size and shape of the systems ..
  9. A new ultra-low field in-vivo EPR technology for biomedical applications
    Inseob Hahn; Fiscal Year: 2012
    ..There are several key factors, which make in vivo EPR methods of human body at high frequencies extremely difficult, the principal ones being limits on the size and shape of the systems ..
  10. DNA Methylation Control Hematopoietic Stem Cell Lineage Differentiation
    GRANT ANTHONY CHALLEN; Fiscal Year: 2013
    ..of Medicine (BCM) is a premier research institute that is committed to research, unraveling the mysteries of the human body, and finding new ways to cure disease and improve health...
  11. Molecular regulation of GM-CSF expression in alveolar epithelial cells
    Robert Paine; Fiscal Year: 2013
    ..provided by applicant): The pulmonary alveolar epithelium forms the largest surface of interaction of the human body with the external environment...
  12. Regulation of Odorant Receptor Gene Expression
    Paul Feinstein; Fiscal Year: 2013
    ..PUBLIC HEALTH RELEVANCE: Gene expression is necessary for cells to function properly in the human body. The sense of smell is critically dependent on olfactory neurons that translate the chemical world to the brain...
  13. Development of an effective therapy against post-exposure Anthrax
    Maurizio Pellecchia; Fiscal Year: 2010
    ..Dependent upon the entry route into the human body, Anthrax can be highly lethal...
  14. The Role of RNA Splicing Factors in Retinal Degeneration
    Michael Farkas; Fiscal Year: 2012
    ..RNA splicing is an essential function that occurs in every cell of the human body where the spliceosome processes pre-mRNA transcripts by removing introns (non-coding regions) and splicing the ..
  15. Haemophilus influenzae iron/heme regulon
    Terrence L Stull; Fiscal Year: 2012
    ..H. influenzae has an absolute growth requirement for heme and the human body is its sole niche. We have characterized several of the heme and iron acquisition systems of H...
  16. Regulation of Bacteroides fragilis multidrug efflux pumps
    Hannah Wexler; Fiscal Year: 2013
    ..fragilis is an important component of the gut microbiome (which has been called a separate "organ" within the human body) that is recognized as having its own impressive metabolic profile and profoundly affects almost every aspect of ..
  17. Quantitation of Tocopherol Metabolism in Humans
    ANDREW JOSEPH CLIFFORD; Fiscal Year: 2010
    ..single oral administration of tracer amounts of the RRR- (natural form) of vitamin E to learn more about how the human body utilizes this vitamin. Particular attention will be directed to the absorption phase...
  18. Regenerating Human Oral Mucosa by Bone Marrow-derived Mesenchymal Stem Cells
    RUBIE ANN RAKIAN; Fiscal Year: 2013
    ..MSC) to regenerate the oral mucosa epithelium by mimicking an environment in vitro similar to that seen in the human body. Bone marrow- derived mesenchymal stem cells (MSC) are capable of self-renewal, differentiation into cell ..
  19. Functional Selection of Novel Ligands from the Neuroendocrine Secretome
    David Larocca; Fiscal Year: 2010
    ..Nowhere in the human body is this leap in complexity from genome to proteome more evident than in the brain...
  20. HIV/NeuroAIDS Patient Derived Induced Pluripotent Stem (iPS) Cells
    Rodney J Nash; Fiscal Year: 2012
    ..stem cells (hESCs), iPS cells can self-renew indefinitely and can be differentiated into most cells of the human body, including the CNS...
  21. Effect of Polybrominated Diphenal Ether Flame Retardant Exposure on Osteogenesis
    Deena J Small; Fiscal Year: 2010
    ..PBDEs are lipid soluble and as such, accumulate within fatty tissues within the human body. These compounds are endocrine disrupting chemicals with a structure very similar to thyroid hormones, although ..
  22. Discovery of Novel Anti-Inflammatory Phytochemicals on Human Cell Platforms
    ERIK MILLS SCHWIEBERT; Fiscal Year: 2010
    ..cells to determine which plant-derived materials are safe and anti-inflammatory and which may be toxic to the human body. This DBM-led partnership seeks to lead a new renaissance in complementary and alternative medicine (CAM) ..
  23. Selectivity and Permeation in the Human Voltage-gated Proton Channel, hHv1
    Susan M E Smith; Fiscal Year: 2013
    ..provided by applicant): The voltage gated proton channel (hHV1) plays crucial roles in many cells in the human body. It enables rapid activity of the enzyme NADPH oxidase that produces reactive oxygen species (ROS)...
  24. Transport ATPases: From Molecules to Maladies
    Rajini Rao; Fiscal Year: 2010
    ..work as nanomotors or metabolic engines, producing virtually all the ATP used to fuel active processes in the human body. Other members control acid-base balance, salt and water movements within, outside and across cell membranes...
  25. Advanced Glycation End-Products and Risk of Pancreatic Cancer
    Li Jiao; Fiscal Year: 2013
    ..All these factors contribute to the formation of Advanced Glycation End products (AGEs) in the human body. AGEs are a heterogeneous group of compounds formed via the nonenzymatic glycation of lipids and proteins...
  26. Diesel Exhaust Particle Effects on Human Immunity to Mycobacterium tuberculosis
    Stephan K Schwander; Fiscal Year: 2010
    ..We will investigate how the combination of diesel exhaust particles and tuberculosis on the human body affect human immune response thus increasing vulnerability to tuberculosis infection and TB disease which may ..
  27. Developing and Improving the UAB Gnotobiotic Facility.
    SAMUEL CORBIN CARTNER; Fiscal Year: 2013
    ..The microbial cells that populate the human body (the microbiota) outnumber the cells of the body itself by an order of magnitude, and the number of genes in ..
  28. ROLE OF B.FRAGILIS OXYGEN STRESS RESPONSE IN INFECTION
    Charles J Smith; Fiscal Year: 2013
    ..PUBLIC HEALTH RELEVANCE: Every mucosal surface of the human body is inhabited by bacteria that have developed a commensal relationship with their host...
  29. Protein inhibitor of galectin-3 to limit fibrosis after myocardial infarction
    MATTHEW LAWRENCE SPRINGER; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): The wound-healing response of the human body to injuries involves induction of fibrosis, which is a dynamic scarring process...
  30. The role of a novel AIF-associated nuclease PAAN1 in neuronal injury
    Yingfei Wang; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): Adult neurons are crucial and precious cell types controlling human body functions. Neuron injury following stroke and other neurologic diseases causes a significant loss of function...
  31. Short-term responses to temperature changes in Escherichia coli
    Christine A White Ziegler; Fiscal Year: 2010
    ..Identification of the bacterial genes more highly expressed at human body temperature (37[unreadable]C) could yield valuable anti-infective targets for chemotherapeutic drugs or vaccines ..
  32. A 3D biomimetic liver sinusoid construct for predicting physiology and toxicity
    Martin L Yarmush; Fiscal Year: 2013
    ..The liver plays a centra role in the human body, contributing to homeostasis and important functions such as biotransformation and metabolism of drugs...
  33. Predicting cell deformation from body level mechanical loads
    Ahmet Erdemir; Fiscal Year: 2012
    ..The goal of this research proposal is to portray that prediction of cell deformations from loads acting on the human body, therefore a clear depiction of the mechanical pathway, is possible, if a multiscale simulation approach is used...
  34. Regulation of Aldosterone Production in the Adrenal
    Wendy B Bollag; Fiscal Year: 2013
    ..is the main mineralocorticoid hormone involved in maintaining fluid and electrolyte (sodium) balance in the human body. However, abnormalities in aldosterone production and secretion from the adrenal gland result in and/or ..
  35. Mechanism of heme regulation of a P. aeruginosa non-coding RNA
    AMANDA GAIL OGLESBY-SHERROUSE; Fiscal Year: 2013
    ..aeruginosa physiology and virulence. Heme is an abundant source of iron in the human body, and its acquisition by P. aeruginosa is hypothesized to play a significant role in infection...
  36. Functional Characterization of CXCL14, CXCL17, and CCL28; three mucosal chemokine
    Albert Zlotnik; Fiscal Year: 2010
    ..would indicate that these chemokines may be major players in maintaining the balance between the mucosa of human body cavities and normal or pathogenic flora present in these sites...
  37. Yeast Based Assays for Chemical Screens Against SARS-CoV Targets
    DANIEL A contact ENGEL; Fiscal Year: 2010
    ..that can reverse the effects of SARS-CoV proteins in yeast will also be able to reverse their effects in the human body during a SARS infection...
  38. Identifying novel anti-infectives by high through-put screening in whole animals
    Frederick M Ausubel; Fiscal Year: 2013
    ..Rather than simply preventing bacteria from growing, these new sophisticated drugs will prevent disease by interfering with a microbe's ability to interact with the human body.
  39. Quantitation of In Vivo Human Lutein Metabolism
    ANDREW JOSEPH CLIFFORD; Fiscal Year: 2010
    ..Therefore, the purpose of this study is to determine how the human body uses lutein and other related compounds.
  40. PROCESSED ANTIGEN CHARACTERIZATION BY MASS SPECTROMETRY
    Donald F Hunt; Fiscal Year: 2012
    DESCRIPTION (provided by applicant): Cells in the human body communicate their health status to the immune system by degrading cellular proteins and presenting fragments of each on the cell surface in association class I MHC proteins...
  41. SODIUM ENTRY INTO AMILORIDE-SENSITIVE EPITHELIA
    Catherine M Fuller; Fiscal Year: 2013
    ..sodium channel (ENaC) proteins and acid-sensing ion channel (ASIC) proteins are distributed all over the human body, are responsible for maintaining the body's salt and water balance, and play a role in hypertension, cancer,..
  42. Role of BH3-domain proteins in the effector phase of RA
    HARRIS R PERLMAN; Fiscal Year: 2012
    ..The regulation of cell death and growth is vital for maintaining a balance in the human body. However, during the initiation and/or progression of the autoimmune disease, rheumatoid arthritis (RA), this ..
  43. Pharmacogenomics of Human P450 Oxidoreductase
    Walter L Miller; Fiscal Year: 2012
    DESCRIPTION (provided by applicant): Most drugs, xenobiotics and environmental pollutants that enter the human body are metabolized by P450 enzymes in the endoplasmic reticulum of liver cells...
  44. STRUCTURAL STUDIES ON PROKARYOTIC POTASSIUM CHANNELS
    Adrian Gross; Fiscal Year: 2013
    ..They are the molecular hardware that generates all electrical signals in the human body. These signals are used to coordinate the beating of the heart and underlie the complex function of the central ..
  45. Structure and Function of Integral Membrane Enzyme Human Aromatase
    Debashis Ghosh; Fiscal Year: 2012
    ..PUBLIC HEALTH RELEVANCE: Aromatase is a unique enzyme that makes all estrogens in the human body. We propose a research plan to unravel the molecular details of how aromatase works and how aromatase inhibitors ..
  46. Somatic hypermutation and class switching in autoimmunity
    Paolo Casali; Fiscal Year: 2013
    ..dysregulation, these studies will help understand how specific pathogenic autoantibodies, as those occurring in patients with SLE, are generated in the human body, eventually leading to the development of better therapeutic approaches.
  47. Bartonella: dissecting niche-specific adaptation in a human pathogen
    Jane E Koehler; Fiscal Year: 2013
    ..of this proposal are: 1) to determine the in vivo role of RpoE-directed transcription in colonization of the human body louse by BQ;and 2) to define the BQ RpoE regulon response to louse stressors in vitro, and identify RpoE-..
  48. A Novel Neuroprotective Protein, Thorase
    Valina L Dawson; Fiscal Year: 2012
    ..Preconditioning amplifies the human body's natural host defense system to provide profound and broad protection...
  49. Optimization of Protein Therapeutics Formulations
    Lawrence J Delucas; Fiscal Year: 2012
    ..drugs such as insulin, vaccines and antibody therapies interact with natural biomolecular processes in the human body to prevent and treat disease...
  50. POLLEN GRAINS AS TROJAN HORSES FOR ORAL VACCINATION
    Harvinder Singh Gill; Fiscal Year: 2012
    ..host-regulated defense at the mucosal surfaces that can neutralize pathogens while they are still outside the human body, before they can cause infection...
  51. Repressing HIF-1: targets and mechanisms
    Nianli Sang; Fiscal Year: 2012
    ....
  52. Structural and Functional Studies of the Novel DBD Domain of MKP5
    Amjad Farooq; Fiscal Year: 2012
    ..MKP5 is a key player in the human body that keeps the activity of a number of proteins involved in causing cancer under control...
  53. A Novel Testicular Germ Cell Maturation Model for Fertility Preservation in Pre-p
    Kirk C Lo; Fiscal Year: 2012
    ..If successful, this will be the first report of human germ cell maturation outside the human body. The major strength of this project is our established human fetal testis xenotransplantation model...
  54. 2013 Apoptotic Cell Recognition &Clearance Gordon Research Conference and Gordon
    NATHALIE CLAUDINE FRANC; Fiscal Year: 2013
    ..by applicant): About 50-200 billion of our cells die daily by apoptosis or programmed cell death in the human body. The mechanisms of apoptosis have been extensively studied, but those of the elimination of apoptotic cells are ..
  55. Long-acting VIP formulations for the treatment of chronic inflammatory diseases
    Sandra Reichstetter; Fiscal Year: 2010
    ..PUBLIC HEALTH RELEVANCE: Vasoactive intestinal peptide (VIP) is a hormone in the human body that can be used for the treatment of autoimmune diseases in animal models...
  56. Role and Regulation of Sodium, Potasium ATPase in Lung
    Jacob I Sznajder; Fiscal Year: 2013
    ..normally as it impairs the transfer of oxygen from the room through the lungs and into all the organs of the human body. For the patient with ARDS to survive the fluid from the lungs needs to be cleared...
  57. Small Regulatory RNA Functions in the Nucleus
    Scott G Kennedy; Fiscal Year: 2012
    ..could theoretically be used to down- regulate any RNA molecule, either foreign or endogenous, present within the human body. Prior to the rational use of siRNAs in the treatment of human disease, however, it is essential that we ..
  58. SIMLAB: Using Patient Simulation for Student Exploration of Community Health Issu
    PATRICIA LEAH WARD; Fiscal Year: 2013
    ..and secondary students', and the general public's awareness, understanding and appreciation of the human body, mind and health...
  59. Lipid Signaling in Chemotaxis
    Miho Iijima; Fiscal Year: 2013
    ..Chemotaxis is highly relevant to development and maintenance of healthy human body as well as the pathogenesis of many diseases such as cancer, asthma, arthritis and atherosclerosis...
  60. Synthesis and properties of a bacterial bioadhesive
    Yves V Brun; Fiscal Year: 2013
    ..Such a property is critical for medical applications in the human body. The general goal of this research is to use a multidisciplinary approach ranging from genetics to biophysics to ..
  61. Biochemical and Functional Analysis of Trypanin
    Kent L Hill; Fiscal Year: 2013
    ..Flagella are required for motility of several human pathogens and are present on most tissues of the human body. They perform motility, transport and sensory functions...
  62. Regulation of Pseudomonas aeruginosa type III secretion
    Timothy L Yahr; Fiscal Year: 2012
    ..medically important bacteria use a so-called type III secretion system to inject toxins into cells found in the human body during infections...
  63. From Nanoparticles to Novel Protective Garments
    Shyamala Rajagopalan; Fiscal Year: 2009
    ..Non-breathable materials retard the human body's process of heat dissipation normally achieved through the evaporation of perspiration...
  64. Assesment of Meridian Theory in the Vascular System
    DAVID DAEKYUNG KIM; Fiscal Year: 2010
    ..The meridian theory deals with physiologic regulation and pathologic changes in the human body, and it guides the diagnosis and treatment of oriental medicine in many aspects, especially in relation to ..
  65. Delayed Hydrogel Tissue Expander
    Yourong Fu; Fiscal Year: 2007
    ..Given the wide range of tissue shapes and sizes encountered in the human body, the ability to reshape the expander by the surgeon with scissors and scalpels is desirable...
  66. Optimized Hydride Generation Systems for Arsenic Specia*
    Miroslav Styblo; Fiscal Year: 2006
    ..The liver is likely the major site for methylation of iAs in human body. The methylated trivalent arsenicals, unlike their pentavalent counterparts, are more potent than iAs as ..
  67. Proline uptake in staphylococcus aureus pathogenesis
    WILLIAM SCHWAN; Fiscal Year: 2002
    ..aureus. Almost every tissue and organ within the human body is susceptible to infections by this species...
  68. CATABOLISM OF POLYSACCHARIDES BY COLONIC BACTEROIDES
    Abigail Salyers; Fiscal Year: 2003
    The normal human colon contains a dense bacterial population, which undoubtedly has many effects on the human body. One important activity of the colonic bacteria is the fermentation of dietary and host-derived polysaccharides...
  69. Validation of Fumonisin and Microcystin Biomarkers
    Jia Sheng Wang; Fiscal Year: 2003
    ..To date, methods are still lack for simultaneously detection of these toxins in environmental samples and human body fluids, which are critical for assessment of human cancer risks, because co-exposure to these biotoxins in high-..
  70. Identifying and Characterizing Histamine Transporters
    ANN STUART; Fiscal Year: 2003
    Histamine is a vitally important messenger in the human body: In the periphery, it regulates vascular permeability, vasoconstriction, inflammation, and acid secretion by the stomach; in the brain it is a neurotransmitter employed by ..
  71. Integrated Microfluidic Platelet Activation Assay
    Lawrence Leung; Fiscal Year: 2009
    DESCRIPTION (provided by applicant): Blood platelets are a key component of the human body's response to injury, whether from external trauma or internal ailments, including diseases from heart disease to cancer...
  72. ROLES OF PILIN GLYCAN IN PATHOGENESIS OF N. GONORRHOEAE
    Asesh Banerjee; Fiscal Year: 2005
    ..that are frequently turned on and off to presumably provide GC with selective advantage in different niches of human body. However, in uncomplicated gonorrheal isolates, this poly- G is generally not present in pgtA...