rhodamine 123

Summary

Summary: A fluorescent probe with low toxicity which is a potent substrate for ATP-BINDING CASSETTE, SUB-FAMILY B, MEMBER 1 and the bacterial multidrug efflux transporter. It is used to assess mitochondrial bioenergetics in living cells and to measure the efflux activity of ATP-BINDING CASSETTE, SUB-FAMILY B, MEMBER 1 in both normal and malignant cells. (Leukemia 1997;11(7):1124-30)