griseofulvin

Summary

Summary: An antifungal agent used in the treatment of TINEA infections.

Top Publications

  1. Singh P, Rathinasamy K, Mohan R, Panda D. Microtubule assembly dynamics: an attractive target for anticancer drugs. IUBMB Life. 2008;60:368-75 pubmed publisher
    ..Benomyl, griseofulvin, and sulfonamides have been used as antifungal and antibacterial drugs...
  2. Bennett M, Fleischer A, Loveless J, Feldman S. Oral griseofulvin remains the treatment of choice for tinea capitis in children. Pediatr Dermatol. 2000;17:304-9 pubmed
    Tinea capitis is one of the most common infections of children. The standard treatment is griseofulvin. Itraconazole and terbinafine have in large part replaced griseofulvin in the treatment of onychomycosis and, in addition to ..
  3. Fuller L, Smith C, Cerio R, Marsden R, Midgley G, Beard A, et al. A randomized comparison of 4 weeks of terbinafine vs. 8 weeks of griseofulvin for the treatment of tinea capitis. Br J Dermatol. 2001;144:321-7 pubmed
    ..S.A. The current licensed treatment in children is griseofulvin 10 mg kg(-1) daily, which is usually given for 6--8 weeks.
  4. Zomorodian K, Uthman U, Tarazooie B, Rezaie S. The effect of griseofulvin on the gene regulation of beta-tubulin in the dermatophyte pathogen Trichophyton rubrum. J Infect Chemother. 2007;13:373-9 pubmed
    b>Griseofulvin - a mold metabolite produced by Penicillium griseofulvum - is an antifungal drug whose interaction with tubulin is poorly understood...
  5. Oliveira C, Ribeiro M, Ricardo N, Souza T, Moura C, Chaibundit C, et al. The effect of water-soluble polymers, PEG and PVP, on the solubilisation of griseofulvin in aqueous micellar solutions of Pluronic F127. Int J Pharm. 2011;421:252-7 pubmed publisher
    ..enhancing the solubilisation capacity of micellar solutions of Pluronic F127 for the poorly water-soluble drug griseofulvin by co-formulating with a water-soluble polymer...
  6. Xia X, Li Q, Li J, Shao C, Zhang J, Zhang Y, et al. Two new derivatives of griseofulvin from the mangrove endophytic fungus Nigrospora sp. (strain No.?1403) from Kandelia candel (L.) Druce. Planta Med. 2011;77:1735-8 pubmed publisher
    ..2), together with four known compounds, griseofulvin (3), dechlorogriseofulvin (4), bostrycin (5), and deoxybostrycin (6), were isolated from the marine endophytic ..
  7. Zili Z, Sfar S, Fessi H. Preparation and characterization of poly-epsilon-caprolactone nanoparticles containing griseofulvin. Int J Pharm. 2005;294:261-7 pubmed
    b>Griseofulvin is an antifungal agent with poor solubility and low bioavailability. The aim of this work was to prepare poly-epsilon-caprolactone nanospheres and nanocapsules of griseofulvin by nanoprecipitation and to characterize them...
  8. Develoux M. [Griseofulvin]. Ann Dermatol Venereol. 2001;128:1317-25 pubmed
    b>Griseofulvin is a metabolic product of Penicillium spp. It was the first available oral agent for the treatment of dermatophytoses and has now been used for more than forty years...
  9. Gupta A, Adam P, Dlova N, Lynde C, Hofstader S, Morar N, et al. Therapeutic options for the treatment of tinea capitis caused by Trichophyton species: griseofulvin versus the new oral antifungal agents, terbinafine, itraconazole, and fluconazole. Pediatr Dermatol. 2001;18:433-8 pubmed
    Tinea capitis is a relatively common fungal infection of childhood. Griseofulvin has been the mainstay of management. However, newer oral antifungal agents are being used more frequently...
  10. Chattopadhyay P, Gupta R. Production of griseofulvin nanoparticles using supercritical CO(2) antisolvent with enhanced mass transfer. Int J Pharm. 2001;228:19-31 pubmed
    b>Griseofulvin (GF) is a poor water soluble, antifungal agent. The bioavailability of the drug and its absorption from the gastrointestinal tract can be greatly improved by particle size reduction...

Detail Information

Publications78

  1. Singh P, Rathinasamy K, Mohan R, Panda D. Microtubule assembly dynamics: an attractive target for anticancer drugs. IUBMB Life. 2008;60:368-75 pubmed publisher
    ..Benomyl, griseofulvin, and sulfonamides have been used as antifungal and antibacterial drugs...
  2. Bennett M, Fleischer A, Loveless J, Feldman S. Oral griseofulvin remains the treatment of choice for tinea capitis in children. Pediatr Dermatol. 2000;17:304-9 pubmed
    Tinea capitis is one of the most common infections of children. The standard treatment is griseofulvin. Itraconazole and terbinafine have in large part replaced griseofulvin in the treatment of onychomycosis and, in addition to ..
  3. Fuller L, Smith C, Cerio R, Marsden R, Midgley G, Beard A, et al. A randomized comparison of 4 weeks of terbinafine vs. 8 weeks of griseofulvin for the treatment of tinea capitis. Br J Dermatol. 2001;144:321-7 pubmed
    ..S.A. The current licensed treatment in children is griseofulvin 10 mg kg(-1) daily, which is usually given for 6--8 weeks.
  4. Zomorodian K, Uthman U, Tarazooie B, Rezaie S. The effect of griseofulvin on the gene regulation of beta-tubulin in the dermatophyte pathogen Trichophyton rubrum. J Infect Chemother. 2007;13:373-9 pubmed
    b>Griseofulvin - a mold metabolite produced by Penicillium griseofulvum - is an antifungal drug whose interaction with tubulin is poorly understood...
  5. Oliveira C, Ribeiro M, Ricardo N, Souza T, Moura C, Chaibundit C, et al. The effect of water-soluble polymers, PEG and PVP, on the solubilisation of griseofulvin in aqueous micellar solutions of Pluronic F127. Int J Pharm. 2011;421:252-7 pubmed publisher
    ..enhancing the solubilisation capacity of micellar solutions of Pluronic F127 for the poorly water-soluble drug griseofulvin by co-formulating with a water-soluble polymer...
  6. Xia X, Li Q, Li J, Shao C, Zhang J, Zhang Y, et al. Two new derivatives of griseofulvin from the mangrove endophytic fungus Nigrospora sp. (strain No.?1403) from Kandelia candel (L.) Druce. Planta Med. 2011;77:1735-8 pubmed publisher
    ..2), together with four known compounds, griseofulvin (3), dechlorogriseofulvin (4), bostrycin (5), and deoxybostrycin (6), were isolated from the marine endophytic ..
  7. Zili Z, Sfar S, Fessi H. Preparation and characterization of poly-epsilon-caprolactone nanoparticles containing griseofulvin. Int J Pharm. 2005;294:261-7 pubmed
    b>Griseofulvin is an antifungal agent with poor solubility and low bioavailability. The aim of this work was to prepare poly-epsilon-caprolactone nanospheres and nanocapsules of griseofulvin by nanoprecipitation and to characterize them...
  8. Develoux M. [Griseofulvin]. Ann Dermatol Venereol. 2001;128:1317-25 pubmed
    b>Griseofulvin is a metabolic product of Penicillium spp. It was the first available oral agent for the treatment of dermatophytoses and has now been used for more than forty years...
  9. Gupta A, Adam P, Dlova N, Lynde C, Hofstader S, Morar N, et al. Therapeutic options for the treatment of tinea capitis caused by Trichophyton species: griseofulvin versus the new oral antifungal agents, terbinafine, itraconazole, and fluconazole. Pediatr Dermatol. 2001;18:433-8 pubmed
    Tinea capitis is a relatively common fungal infection of childhood. Griseofulvin has been the mainstay of management. However, newer oral antifungal agents are being used more frequently...
  10. Chattopadhyay P, Gupta R. Production of griseofulvin nanoparticles using supercritical CO(2) antisolvent with enhanced mass transfer. Int J Pharm. 2001;228:19-31 pubmed
    b>Griseofulvin (GF) is a poor water soluble, antifungal agent. The bioavailability of the drug and its absorption from the gastrointestinal tract can be greatly improved by particle size reduction...
  11. Yang D, Kulkarni R, Behme R, Kotiyan P. Effect of the melt granulation technique on the dissolution characteristics of griseofulvin. Int J Pharm. 2007;329:72-80 pubmed
    ..a melt granulation technique to improve the dissolution characteristics of a poorly water-soluble drug, griseofulvin. Melt granulation technique is a process by which pharmaceutical powders are efficiently agglomerated by a ..
  12. Rebacz B, Larsen T, Clausen M, Rønnest M, Loffler H, Ho A, et al. Identification of griseofulvin as an inhibitor of centrosomal clustering in a phenotype-based screen. Cancer Res. 2007;67:6342-50 pubmed
    ..Screening of this compound library led to the identification of griseofulvin, which induced multipolar spindles by inhibition of centrosome coalescence, mitotic arrest, and subsequent cell ..
  13. Aggarwal N, Goindi S. Preparation and in vivo evaluation of solid lipid nanoparticles of griseofulvin for dermal use. J Biomed Nanotechnol. 2013;9:564-76 pubmed
    b>Griseofulvin-loaded solid lipid nanoparticles (SLNs) were prepared by hot microemulsion technique and optimized for type and concentration of lipid and surfactant...
  14. Pacchierotti F, Bassani B, Marchetti F, Tiveron C. Griseofulvin induces mitotic delay and aneuploidy in bone marrow cells of orally treated mice. Mutagenesis. 2002;17:219-22 pubmed
    b>Griseofulvin (GF) is a fungicide drug well characterized for its aneugenic activity in vitro. In vivo strong evidence of aneuploidy and polyploidy induction has been obtained in germ cells, especially in oocytes...
  15. Arida A, Al Tabakha M, Hamoury H. Improving the high variable bioavailability of griseofulvin by SEDDS. Chem Pharm Bull (Tokyo). 2007;55:1713-9 pubmed
    To enhance the dissolution and oral absorption of poorly water-soluble griseofulvin (GF), self-emulsifying drug delivery system (SEDDS) composed of oil, surfactant and cosurfactant for oral administration of griseofulvin was formulated, ..
  16. Dastghaib L, Azizzadeh M, Jafari P. Therapeutic options for the treatment of tinea capitis: griseofulvin versus fluconazole. J Dermatolog Treat. 2005;16:43-6 pubmed
    Tinea capitis is a relatively common fungal infection of childhood. Griseofulvin has been the mainstay of treatment for many years. However, newer oral antifungal agents are being used more frequently.
  17. Kassem M, Esmat S, Bendas E, El Komy M. Efficacy of topical griseofulvin in treatment of tinea corporis. Mycoses. 2006;49:232-5 pubmed
    Tinea infections are among the most common dermatological conditions throughout the world. Griseofulvin is a classical oral fungistatic antibiotic, active against Epidermophyton floccosum, Trichophyton and Microsporum species, the ..
  18. Chooi Y, Cacho R, Tang Y. Identification of the viridicatumtoxin and griseofulvin gene clusters from Penicillium aethiopicum. Chem Biol. 2010;17:483-94 pubmed publisher
    ..and biologically active polyketides: the tetracycline-like viridicatumtoxin 1 and the classic antifungal agent griseofulvin 2...
  19. Petit K, Mondeguer F, Roquebert M, Biard J, Pouchus Y. Detection of griseofulvin in a marine strain of Penicillium waksmanii by ion trap mass spectrometry. J Microbiol Methods. 2004;58:59-65 pubmed
    ..of a monocharged ion at m/z 353 containing a chlorine atom, which could be attributed to the antifungal griseofulvin [C17H17ClO6+H]+...
  20. Laftah A, Raja K, Beaumont N, Simpson R, Deacon A, Solanky N, et al. The effects of inhibition of haem biosynthesis by griseofulvin on intestinal iron absorption. Basic Clin Pharmacol Toxicol. 2004;94:161-8 pubmed
    ..intestinal iron absorption in mice was investigated by ascertaining the effect of the haem synthesis inhibitor, griseofulvin, on duodenal iron absorption using both in vivo and in vitro measurements...
  21. Panda D, Rathinasamy K, Santra M, Wilson L. Kinetic suppression of microtubule dynamic instability by griseofulvin: implications for its possible use in the treatment of cancer. Proc Natl Acad Sci U S A. 2005;102:9878-83 pubmed
    The antifungal drug griseofulvin inhibits mitosis strongly in fungal cells and weakly in mammalian cells by affecting mitotic spindle microtubule (MT) function...
  22. Rathinasamy K, Jindal B, Asthana J, Singh P, Balaji P, Panda D. Griseofulvin stabilizes microtubule dynamics, activates p53 and inhibits the proliferation of MCF-7 cells synergistically with vinblastine. BMC Cancer. 2010;10:213 pubmed publisher
    b>Griseofulvin, an antifungal drug, has recently been shown to inhibit proliferation of various types of cancer cells and to inhibit tumor growth in athymic mice...
  23. Pierri E, Avgoustakis K. Poly(lactide)-poly(ethylene glycol) micelles as a carrier for griseofulvin. J Biomed Mater Res A. 2005;75:639-47 pubmed
    In this work, the feasibility to develop micelle carriers of griseofulvin based on PLA-PEG copolymers was investigated...
  24. Czymmek K, Bourett T, Shao Y, DeZwaan T, Sweigard J, Howard R. Live-cell imaging of tubulin in the filamentous fungus Magnaporthe grisea treated with anti-microtubule and anti-microfilament agents. Protoplasma. 2005;225:23-32 pubmed
    ..Treatment with either benomyl or griseofulvin resulted in the appearance of prominent brightly fluorescent aggregates, including a large aggregate near the ..
  25. Saito M, Ugajin T, Nozawa Y, Sadzuka Y, Miyagishima A, Sonobe T. Preparation and dissolution characteristics of griseofulvin solid dispersions with saccharides. Int J Pharm. 2002;249:71-9 pubmed
    To improve the solubility of poorly water-soluble drugs, we studied physical characteristics of griseofulvin (GF) solid dispersions with saccharides as the dispersion carrier using a roll mixing method...
  26. Rønnest M, Rebacz B, Markworth L, Terp A, Larsen T, Krämer A, et al. Synthesis and structure-activity relationship of griseofulvin analogues as inhibitors of centrosomal clustering in cancer cells. J Med Chem. 2009;52:3342-7 pubmed publisher
    b>Griseofulvin was identified as an inhibitor of centrosomal clustering in a recently developed assay...
  27. Ho Y, Duh J, Jeng J, Wang Y, Liang Y, Lin C, et al. Griseofulvin potentiates antitumorigenesis effects of nocodazole through induction of apoptosis and G2/M cell cycle arrest in human colorectal cancer cells. Int J Cancer. 2001;91:393-401 pubmed
    ..that apoptosis and G2/M cell cycle arrest were easily induced by treatment with the oral-antifungal agent, griseofulvin (GF)...
  28. Naseem A, Olliff C, Martini L, Lloyd A. Effects of plasma irradiation on the wettability and dissolution of compacts of griseofulvin. Int J Pharm. 2004;269:443-50 pubmed
    ..was investigated as a possible technique for increasing the dissolution rate of the poorly soluble drug griseofulvin. Plasma is a partially ionised gas consisting of ions, electrons and neutral species...
  29. Jadon P, Gajbhiye V, Jadon R, Gajbhiye K, Ganesh N. Enhanced oral bioavailability of griseofulvin via niosomes. AAPS PharmSciTech. 2009;10:1186-92 pubmed publisher
    ..was to develop nonionic surfactant vesicles (niosomes) to improve poor and variable oral bioavailability of griseofulvin. Niosomes were prepared by using different nonionic surfactants span 20, span 40, and span 60...
  30. Uen Y, Liu D, Weng M, Ho Y, Lin S. NF-kappaB pathway is involved in griseofulvin-induced G2/M arrest and apoptosis in HL-60 cells. J Cell Biochem. 2007;101:1165-75 pubmed
    b>Griseofulvin (GF), an oral antifungal agent, has been shown to exert antitumorigenesis effect through G2/M cell cycle arrest in colon cancer cells. But the underlying mechanisms remained obscure...
  31. Fleece D, Gaughan J, Aronoff S. Griseofulvin versus terbinafine in the treatment of tinea capitis: a meta-analysis of randomized, clinical trials. Pediatrics. 2004;114:1312-5 pubmed
    ..Although the current treatment of choice is oral griseofulvin, terbinafine has been shown to be variably effective in several comparative, randomized trials...
  32. Reverchon E, Della Porta G, Spada A, Antonacci A. Griseofulvin micronization and dissolution rate improvement by supercritical assisted atomization. J Pharm Pharmacol. 2004;56:1379-87 pubmed
    Supercritical assisted atomization (SAA) was used to micronize griseofulvin (GF), selected as a model compound, to verify the performance of this innovative process...
  33. Ahmed I, Aboul Einien M. In vitro and in vivo evaluation of a fast-disintegrating lyophilized dry emulsion tablet containing griseofulvin. Eur J Pharm Sci. 2007;32:58-68 pubmed
    ..lyophilized dry emulsion (LDE) tablet that enhanced the in vitro dissolution and in vivo absorption of griseofulvin (GF) is presented...
  34. Caceres Rios H, Rueda M, Ballona R, Bustamante B. Comparison of terbinafine and griseofulvin in the treatment of tinea capitis. J Am Acad Dermatol. 2000;42:80-4 pubmed
    b>Griseofulvin has been used for many years in the treatment of tinea capitis. Increase in resistance to this medication has led to a search for new therapeutic alternatives.
  35. Hussain I, Muzaffar F, Rashid T, Ahmad T, Jahangir M, Haroon T. A randomized, comparative trial of treatment of kerion celsi with griseofulvin plus oral prednisolone vs. griseofulvin alone. Med Mycol. 1999;37:97-9 pubmed
    ..In this randomized study, the efficacy of combination therapy with oral griseofulvin and oral prednisolone (n =17) was compared to oral griseofulvin alone (n=13) in the treatment of kerion celsi...
  36. Elewski B, Cáceres H, DeLeon L, El Shimy S, Hunter J, Korotkiy N, et al. Terbinafine hydrochloride oral granules versus oral griseofulvin suspension in children with tinea capitis: results of two randomized, investigator-blinded, multicenter, international, controlled trials. J Am Acad Dermatol. 2008;59:41-54 pubmed publisher
    Although griseofulvin is currently considered the primary antifungal agent used to treat tinea capitis in many countries, increasingly higher doses and longer durations of treatment are becoming necessary to achieve effective treatment...
  37. Gupta A, Cooper E, Bowen J. Meta-analysis: griseofulvin efficacy in the treatment of tinea capitis. J Drugs Dermatol. 2008;7:369-72 pubmed
    Despite its long history in clinical use, reported efficacy rates of griseofulvin remain highly variable. A meta-analysis of clinical trials of griseofulvin use in tinea capitis was performed to determine mean griseofulvin efficacy...
  38. Kim Y, Alpmann P, Blaum Feder S, Kramer S, Endo T, Lu D, et al. In vivo efficacy of griseofulvin against multiple myeloma. Leuk Res. 2011;35:1070-3 pubmed publisher
    We recently confirmed that ciclopirox olamine inhibits Wnt/beta catenin signalling in myeloma. Griseofulvin (GF) has similar chemical features as compared to ciclopirox olamine. In this study the anti-tumor effect of GF was investigated...
  39. Inafuku K, Takamiyagi A, Oshiro M, Kinjo T, Nakashima Y, Nonaka S. Alteration of mRNA levels of delta-aminolevulinic acid synthase, ferrochelatase and heme oxygenase-1 in griseofulvin induced protoporphyria mice. J Dermatol Sci. 1999;19:189-98 pubmed
    ..inherited disorder of porphyrin metabolism and its experimental murine model can be produced by treatment with griseofulvin (GF)...
  40. Gupta A, Gregurek Novak T. Efficacy of itraconazole, terbinafine, fluconazole, griseofulvin and ketoconazole in the treatment of Scopulariopsis brevicaulis causing onychomycosis of the toes. Dermatology. 2001;202:235-8 pubmed
    ..To evaluate the efficacy and safety of the oral antifungal agents griseofulvin, ketoconazole, itraconazole, fluconazole and terbinafine in the treatment of S. brevicaulis...
  41. Lipozencic J, Skerlev M, Orofino Costa R, Zaitz V, Horvath A, Chouela E, et al. A randomized, double-blind, parallel-group, duration-finding study of oral terbinafine and open-label, high-dose griseofulvin in children with tinea capitis due to Microsporum species. Br J Dermatol. 2002;146:816-23 pubmed
    ..However, the optimal treatment duration for its use in the treatment of tinea capitis caused by Microsporum species has not yet been determined...
  42. Noel C, Gerbod D, Delgado Viscogliosi P, Fast N, Younes A, Chose O, et al. Morphogenesis during division and griseofulvin-induced changes of the microtubular cytoskeleton in the parasitic protist, Trichomonas vaginalis. Parasitol Res. 2003;89:487-94 pubmed
    ..Observation of griseofulvin-treated T...
  43. Fortier A, Riopel K, Desaulniers M, Cadrin M. Novel insights into changes in biochemical properties of keratins 8 and 18 in griseofulvin-induced toxic liver injury. Exp Mol Pathol. 2010;89:117-25 pubmed publisher
    ..Treatment of mice with a diet containing griseofulvin induces the formation of Mallory-Denk bodies in hepatocytes...
  44. Trotta M, Gallarate M, Carlotti M, Morel S. Preparation of griseofulvin nanoparticles from water-dilutable microemulsions. Int J Pharm. 2003;254:235-42 pubmed
    Nanoparticles of griseofulvin, a model drug with poor solubility and low bioavailability, were prepared from water dilutable microemulsions by the solvent diffusion technique...
  45. Martinez M, Afonso S, Meiss R, Buzaleh A, Batlle A. Hepatic damage and oxidative stress induced by Griseofulvin in mice. Cell Mol Biol (Noisy-le-grand). 2009;55:127-39 pubmed
    ..In some cases, a severe hepatic failure and cholestasis was observed. Griseofulvin (Gris) develops an experimental EPP with hepatic manifestations in animals...
  46. Singal A, Rawat S, Bhattacharya S, Mohanty S, Baruah M. Clinico-myocological profile of tinea capitis in North India and response to griseofulvin. J Dermatol. 2001;28:22-6 pubmed
    There is a paucity of literature on tinea capitis from North India. The response to griseofulvin has not been studied as well...
  47. Berasain C, Sampedro A, Mauleon I, Goni S, Latasa M, Matscheko N, et al. Epidermal growth factor receptor ligands in murine models for erythropoietic protoporphyria: potential novel players in the progression of liver injury. Cell Mol Biol (Noisy-le-grand). 2009;55:29-37 pubmed
    ..Similarly, chronic administration of griseofulvin to mice induces pathological changes similar to those found in patients with EPP-associated liver injury...
  48. Puza C, Cardones A. Concepts and controversies in the treatment of cutaneous lichen planus. G Ital Dermatol Venereol. 2017;152:607-614 pubmed publisher
    ..Other treatments that have been investigated include sulfasalazine, low molecular weight heparin, griseofulvin, hydroxychloroquine, metronidazole and dapsone.
  49. Karad S, Purohit V, Thakor P, Thakkar V, Raval D. Novel morpholinoquinoline nucleus clubbed with pyrazoline scaffolds: Synthesis, antibacterial, antitubercular and antimalarial activities. Eur J Med Chem. 2016;112:270-279 pubmed publisher
    ..against Candida albicans, compounds 6c, 7c, 8a, 8b, 8c and 9b showed significant activity as compared to griseofulvin (1147 μM). Compounds 8b, 6b, 9d, 6a, 9b, 7b and 8a displayed brilliant activity against P...
  50. Rayala B, Morrell D. Common Skin Conditions in Children: Skin Infections. FP Essent. 2017;453:26-32 pubmed
    ..Management consists of topical and systemic antifungals, including nystatin, triazoles, terbinafine, griseofulvin, and imidazoles...
  51. Davies R, Schuurman A, Barker C, Clothier B, Chernova T, Higginson F, et al. Hepatic gene expression in protoporphyic Fech mice is associated with cholestatic injury but not a marked depletion of the heme regulatory pool. Am J Pathol. 2005;166:1041-53 pubmed
    ..In contrast, in BALB/c mice exhibiting griseofulvin-induced hepatic protoporphyria with induction and destruction of cytochrome P450, both Alas1 and Hmox1 genes ..
  52. Kamiya S, Kurita T, Miyagishima A, Arakawa M. Preparation of griseofulvin nanoparticle suspension by high-pressure homogenization and preservation of the suspension with saccharides and sugar alcohols. Drug Dev Ind Pharm. 2009;35:1022-8 pubmed publisher
    ..b>Griseofulvin (GF)-lipid nanoparticle suspension is prepared using GF and a lipid by high-pressure homogenization...
  53. Mourtas S, Fotopoulou S, Duraj S, Sfika V, Tsakiroglou C, Antimisiaris S. Liposomal drugs dispersed in hydrogels. Effect of liposome, drug and gel properties on drug release kinetics. Colloids Surf B Biointerfaces. 2007;55:212-21 pubmed
    Release of calcein and griseofulvin (GRF) from control (gels in which solutes are dissolved in) and liposomal gels was studied using agarose-assisted immobilization as a technique to separate gels from drug-receptor compartments...
  54. Shibata Y, Fujii M, Kokudai M, Noda S, Okada H, Kondoh M, et al. Effect of characteristics of compounds on maintenance of an amorphous state in solid dispersion with crospovidone. J Pharm Sci. 2007;96:1537-47 pubmed
    ..It was suggested that the presence of a hydrogen-bond-donor functional group in a compound is an important factor affecting the stable formation of SD with CrosPVP, which contains a hydrogen-bond acceptor. ..
  55. Di Landro A, Marchesi L, Passera M, Arosio M. Tinea capitis due to Trichophyton soudanense with a papular IDE reaction in Northern Italy. G Ital Dermatol Venereol. 2008;143:421-4 pubmed
  56. Li L, Li G, Huang W. [Preparation of drug-loaded polylactic acid nanospheres and drug-releasing performance evaluation]. Di Yi Jun Yi Da Xue Xue Bao. 2004;24:352-4 pubmed
    The polylactic acid (PLA) nanospheres containing griseofulvin were prepared by a water-in-oil solvent evaporation method adopting an uniformly designed experiment, and the drug-releasing rates were compared between the microsphere and ..
  57. Sehgal V, Sharma S, Khandpur S. Twenty-nail dystrophy originating from lichen planus. Skinmed. 2005;4:58-9 pubmed
  58. Gottsch J, Bynoe L, Harlan J, Rencs E, Green W. Light-induced deposits in Bruch's membrane of protoporphyric mice. Arch Ophthalmol. 1993;111:126-9 pubmed
  59. Colton R, Amir J, Mimouni M, Zeharia A. Serum sickness-like reaction associated with griseofulvin. Ann Pharmacother. 2004;38:609-11 pubmed
    To describe a serum sickness-like reaction associated with griseofulvin in a child being treated for tinea capitis...
  60. Sehgal A, Osgood C, Zimmering S. Aneuploidy in Drosophila. III: Aneuploidogens inhibit in vitro assembly of taxol-purified Drosophila microtubules. Environ Mol Mutagen. 1990;16:217-24 pubmed
    ..Colchicine, acetonitrile, propionitrile, acrylonitrile, dimethylsulfoxide (DMSO), griseofulvin, and cadmium chloride inhibit microtubule assembly, whereas methoxyethyl acetate (MEA) does not...
  61. Jimenez Puya R, Vazquez Bayo C, Rodríguez Bujaldon A, Gomez Garcia F, Moreno Giménez J. Extensive tinea in a patient with severe combined immunodeficiency. Pediatr Dermatol. 2009;26:213-4 pubmed publisher
    ..While SCID may present with many nosocomial infections, dermatophyte infections are not common. We reported a case of SCID which was associated with a widespread skin infection with Trichophyton mentagrophytes. ..
  62. Feng T, Pinal R, Carvajal M. Process induced disorder in crystalline materials: differentiating defective crystals from the amorphous form of griseofulvin. J Pharm Sci. 2008;97:3207-21 pubmed
    This research investigates milling induced disorder in crystalline griseofulvin. Griseofulvin was subjected to cryogenic milling for various lengths of time...
  63. Sievens Figueroa L, Pandya N, Bhakay A, Keyvan G, Michniak Kohn B, Bilgili E, et al. Using USP I and USP IV for discriminating dissolution rates of nano- and microparticle-loaded pharmaceutical strip-films. AAPS PharmSciTech. 2012;13:1473-82 pubmed publisher
    ..In this work, we consider the dissolution testing of griseofulvin (GF) particles, a poorly water-soluble compound, incorporated into a strip-film dosage form...
  64. von Heimendahl A, England G, Sheldon I. Influence of Griseofulvin treatment on semen quality in the dog. Anim Reprod Sci. 2004;80:175-81 pubmed
    b>Griseofulvin is used to treat dermatomycosis in many species and causes oligospermia in supra-pharmacological doses...
  65. Lateur N. [How to cope with tinea capitis?]. Rev Med Brux. 2004;25:148-52 pubmed
    ..This explains why, in 2001-2002, we had some epidemics in schools and creches. Griseofulvin, the gold treatment, was withdrawn from the Belgian market in 1997...
  66. Calafato N, Picó G. Griseofulvin and ketoconazole solubilization by bile salts studied using fluorescence spectroscopy. Colloids Surf B Biointerfaces. 2006;47:198-204 pubmed
    ..hiocholate, quenodeoxicholate and taurocholate were assayed on two low aqueous soluble antimicotic agents: griseofulvin and ketoconazole...
  67. Knöös P, Topgaard D, Wahlgren M, Ulvenlund S, Piculell L. Using NMR chemical shift imaging to monitor swelling and molecular transport in drug-loaded tablets of hydrophobically modified poly(acrylic acid): methodology and effects of polymer (in)solubility. Langmuir. 2013;29:13898-908 pubmed publisher
    ..The studied tablets contained hydrophobically modified poly(acrylic acid) (HMPAA) as the polymer component and griseofulvin and ethanol as hydrophobic and hydrophilic, respectively, low-molecular weight model compounds...