clindamycin

Summary

Summary: An antibacterial agent that is a semisynthetic analog of LINCOMYCIN.

Top Publications

  1. Deotale V, Mendiratta D, Raut U, Narang P. Inducible clindamycin resistance in Staphylococcus aureus isolated from clinical samples. Indian J Med Microbiol. 2010;28:124-6 pubmed publisher
    b>Clindamycin is commonly used in the treatment of erythromycin resistant Staphylococcus aureus causing skin and soft tissue infections...
  2. Muller A, Mouton J, Oostvogel P, Dörr P, Voskuyl R, DeJongh J, et al. Pharmacokinetics of clindamycin in pregnant women in the peripartum period. Antimicrob Agents Chemother. 2010;54:2175-81 pubmed publisher
    The study presented here was performed to determine the pharmacokinetics of intravenously administered clindamycin in pregnant women. Seven pregnant women treated with clindamycin were recruited...
  3. Chen B, George R, Walsh L. Root discolouration following short-term application of steroid medicaments containing clindamycin, doxycycline or demeclocycline. Aust Endod J. 2012;38:124-8 pubmed publisher
    ..of 120 root samples were prepared and the canals filled with either Ledermix (demeclocyline), Odontopaste (clindamycin) or DoxyPaste (doxycycline)...
  4. Krausse R, Schubert S. In-vitro activities of tetracyclines, macrolides, fluoroquinolones and clindamycin against Mycoplasma hominis and Ureaplasma ssp. isolated in Germany over 20 years. Clin Microbiol Infect. 2010;16:1649-55 pubmed publisher
    ..5 mg/L) against ureaplasmas. Erythromycin had the lowest activity (MIC?? of 8 mg/L) against ureaplasmas like clindamycin which was the most potent agent against M. hominis...
  5. Imperi M, Gherardi G, Berardi A, Baldassarri L, Pataracchia M, Dicuonzo G, et al. Invasive neonatal GBS infections from an area-based surveillance study in Italy. Clin Microbiol Infect. 2011;17:1834-9 pubmed publisher
    ..Resistance to erythromycin (12%) was associated with a constitutive resistance to clindamycin in five cases (four carrying the erm(B) gene and one both the erm(B) and mef(E) genes) and with an inducible ..
  6. Spigaglia P, Barbanti F, Mastrantonio P. Multidrug resistance in European Clostridium difficile clinical isolates. J Antimicrob Chemother. 2011;66:2227-34 pubmed publisher
    ..In particular, 48% of these isolates were resistant to erythromycin, clindamycin, moxifloxacin and rifampicin...
  7. Kostopoulou O, Papadopoulos G, Kouvela E, Kalpaxis D. Clindamycin binding to ribosomes revisited: foot printing and computational detection of two binding sites within the peptidyl transferase center. Pharmazie. 2013;68:616-21 pubmed
    b>Clindamycin is a semi-synthetic lincosamide, active against most Gram-positive bacteria and some protozoa. It binds to the 50S ribosomal subunit and inhibits early peptide chain elongation...
  8. Saridomichelakis M, Athanasiou L, Salame M, Chatzis M, Katsoudas V, Pappas I. Serum pharmacokinetics of clindamycin hydrochloride in normal dogs when administered at two dosage regimens. Vet Dermatol. 2011;22:429-35 pubmed publisher
    The aim of this cross-over study was to compare clindamycin pharmacokinetics in the serum of clinically normal dogs when administered orally at two dosage regimens (5...
  9. Lemaire S, Van Bambeke F, Pierard D, Appelbaum P, Tulkens P. Activity of fusidic acid against extracellular and intracellular Staphylococcus aureus: influence of pH and comparison with linezolid and clindamycin. Clin Infect Dis. 2011;52 Suppl 7:S493-503 pubmed publisher
    ..inhibitory concentration) in parallel with an increase of drug bacterial accumulation (opposite effects for clindamycin; linezolid remained unaffected). Fusidic acid accumulated in THP-1 cells (about 5...

Scientific Experts

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Publications62

  1. Athanassiadis M, Jacobsen N, Parashos P. The effect of calcium hydroxide on the steroid component of Ledermix and Odontopaste. Int Endod J. 2011;44:1162-9 pubmed publisher
    ..To investigate the chemical interaction of calcium hydroxide with the corticosteroid triamcinolone acetonide in Ledermix Paste and in Odontopaste, a new steroid/antibiotic paste...
  2. Goreshi R, Samrao A, Ehst B. A double-blind, randomized, bilateral comparison of skin irritancy following application of the combination acne products clindamycin/tretinoin and benzoyl peroxide/adapalene. J Drugs Dermatol. 2012;11:1422-6 pubmed
    ..We sought to compare the tolerability of 2 combination topical acne products, clindamycin 1.2%-tretinoin 0.025% (CLIN/RA) gel and benzoyl peroxide 2.5%-adapalene 0.1% (BPO/ADA) gel...
  3. Chuang C, Hsiao C, Tan H, Ma D, Lin K, Chang C, et al. Staphylococcus aureus ocular infection: methicillin-resistance, clinical features, and antibiotic susceptibilities. PLoS ONE. 2012;8:e42437 pubmed publisher
    ..aureus (MSSA) infections...
  4. Wang L, Liu Y, Yang Y, Huang G, Wang C, Deng L, et al. Multidrug-resistant clones of community-associated meticillin-resistant Staphylococcus aureus isolated from Chinese children and the resistance genes to clindamycin and mupirocin. J Med Microbiol. 2012;61:1240-7 pubmed publisher
    ..CA) meticillin-resistant Staphylococcus aureus (MRSA) to identify the genes responsible for clindamycin and mupirocin resistance in S. aureus isolates from paediatric hospitals in mainland China. A total of 435 S...
  5. Herigon J, Hersh A, Gerber J, Zaoutis T, Newland J. Antibiotic management of Staphylococcus aureus infections in US children's hospitals, 1999-2008. Pediatrics. 2010;125:e1294-300 pubmed publisher
    ..Trends in the use of vancomycin, clindamycin, linezolid, trimethoprim-sulfamethoxazole, cefazolin, and oxacillin/nafcillin were examined for percentage use ..
  6. Nemec A, Pavlica Z, Nemec Svete A, Erzen D, Milutinovic A, Petelin M. Aerosolized clindamycin is superior to aerosolized dexamethasone or clindamycin-dexamethasone combination in the treatment of severe Porphyromonas gingivalis aspiration pneumonia in an experimental murine model. Exp Lung Res. 2012;38:9-18 pubmed publisher
    ..response, mice were intratracheally inoculated with live Porphyromonas gingivalis and treated with either clindamycin (C), dexamethasone (D), C+D combination, or were not treated (Pg)...
  7. Lasave A, Diaz Llopis M, Muccioli C, Belfort R, Arevalo J. Intravitreal clindamycin and dexamethasone for zone 1 toxoplasmic retinochoroiditis at twenty-four months. Ophthalmology. 2010;117:1831-8 pubmed publisher
    To report the anatomic and functional outcomes of intravitreal clindamycin and dexamethasone for the treatment of zone 1 toxoplasmic retinochoroiditis (TRC)...
  8. Khawcharoenporn T, Tice A. Empiric outpatient therapy with trimethoprim-sulfamethoxazole, cephalexin, or clindamycin for cellulitis. Am J Med. 2010;123:942-50 pubmed publisher
    ..Limited data exist on optimal empiric oral antibiotic treatment for outpatients with cellulitis in areas with a high prevalence of community-associated methicillin-resistant Staphylococcus aureus (MRSA) infections...
  9. Togni G, Battini V, Bulgheroni A, Mailland F, Caserini M, Mendling W. In vitro activity of nifuratel on vaginal bacteria: could it be a good candidate for the treatment of bacterial vaginosis?. Antimicrob Agents Chemother. 2011;55:2490-2 pubmed publisher
    ..vaginae, and lactobacilli was compared with that of the two currently used antibiotics metronidazole and clindamycin. Results suggest that nifuratel has a better spectrum of activity, being highly active against G...
  10. Kim J, Pai H, Seo M, Kang J. Clinical and microbiologic characteristics of tcdA-negative variant Clostridium difficile infections. BMC Infect Dis. 2012;12:109 pubmed publisher
    ..Previous use of clindamycin and young age were identified as significant risk factors for the acquisition of A-B+ CDI (OR = 4.738, 95% CI 1...
  11. Larsson P, Brandsborg E, Forsum U, Pendharkar S, Andersen K, Nasic S, et al. Extended antimicrobial treatment of bacterial vaginosis combined with human lactobacilli to find the best treatment and minimize the risk of relapses. BMC Infect Dis. 2011;11:223 pubmed publisher
    ..more aggressive treatment of BV than used in normal clinical practice with repeated antibiotic treatment with clindamycin and metronidazole together with vaginal gelatine capsules containing different strains of lactobacilli both ..
  12. Peltola H, Paakkonen M, Kallio P, Kallio M. Clindamycin vs. first-generation cephalosporins for acute osteoarticular infections of childhood--a prospective quasi-randomized controlled trial. Clin Microbiol Infect. 2012;18:582-9 pubmed publisher
    ..We conducted a prospective, multicentre, quasi-randomized trial in Finland, comparing clindamycin with first-generation cephalosporins...
  13. Yamaki J, Synold T, Wong Beringer A. Antivirulence potential of TR-700 and clindamycin on clinical isolates of Staphylococcus aureus producing phenol-soluble modulins. Antimicrob Agents Chemother. 2011;55:4432-5 pubmed publisher
    ..TR-700 (oxazolidinone) and clindamycin strongly inhibited PSM production at one-half the MIC but exhibited weak to modest induction at one-fourth and ..
  14. Al Talla Z, Akrawi S, Emwas A. Solid state NMR and bioequivalence comparison of the pharmacokinetic parameters of two formulations of clindamycin. Int J Clin Pharmacol Ther. 2011;49:469-76 pubmed
    ..was to compare the pharmacokinetic parameters and determine the bioequivalence of a generic formulation of clindamycin that is sold in the local markets in the Middle East (Clindox® 150 mg capsule; test) with a reference ..
  15. Watanabe N, Suzuki T, Kitano E, Kitamura H, Hatanaka M, Sago H. Successful pregnancy in a patient suffering from recurrent mid-trimester miscarriage with C9 deficiency after receiving cervical cerclage followed by clindamycin and progesterone: a case report. J Obstet Gynaecol Res. 2012;38:562-6 pubmed publisher
    ..Her fifth pregnancy was successfully managed by cervical cerclage at 13 weeks' gestation, followed by clindamycin administration (600 mg/day for 7 days) and progesterone injections (250 mg/week)...
  16. Bidoli P, Cortinovis D, Colombo I, Crippa A, Cicchiello F, Villa F, et al. Isotretinoin plus clindamycin seem highly effective against severe erlotinib-induced skin rash in advanced non-small cell lung cancer. J Thorac Oncol. 2010;5:1662-3 pubmed publisher
    ..We carried out a preliminary investigation on isotretinoin and clindamycin. Among 56 advanced lung cancer patients treated with erlotinib, 31 (53%) developed rash...
  17. Shahi S, Singh V, Kumar A, Gupta S, Singh S. Interaction of dihydrofolate reductase and aminoglycoside adenyltransferase enzyme from Klebsiella pneumoniae multidrug resistant strain DF12SA with clindamycin: a molecular modelling and docking study. J Mol Model. 2013;19:973-83 pubmed publisher
    ..augmentin, co-trimoxazole, carbapenems, penicillins and cefoperazone, and was sensitive to clindamycin. Molecular characterization of the multidrug-resistance phenotype revealed the presence of a class 1 integron ..
  18. Dharia N, Plouffe D, Bopp S, González Páez G, Lucas C, Salas C, et al. Genome scanning of Amazonian Plasmodium falciparum shows subtelomeric instability and clindamycin-resistant parasites. Genome Res. 2010;20:1534-44 pubmed publisher
    ..isolates we discovered point mutations in the apicoplast genome that are close to known mutations that confer clindamycin resistance in other species, but which were hitherto unknown in malaria parasites...
  19. Obonyo C, Juma E. Clindamycin plus quinine for treating uncomplicated falciparum malaria: a systematic review and meta-analysis. Malar J. 2012;11:2 pubmed publisher
    ..b>Clindamycin plus quinine is an alternative non-artemisinin-based combination recommended by World Health Organization...
  20. Soheilian M, Ramezani A, Azimzadeh A, Sadoughi M, Dehghan M, Shahghadami R, et al. Randomized trial of intravitreal clindamycin and dexamethasone versus pyrimethamine, sulfadiazine, and prednisolone in treatment of ocular toxoplasmosis. Ophthalmology. 2011;118:134-41 pubmed publisher
    To compare the efficacy of intravitreal injection of clindamycin and dexamethasone with classic treatment for ocular toxoplasmosis. Prospective, randomized single-masked clinical trial...
  21. Seidler E, Kimball A. Meta-analysis comparing efficacy of benzoyl peroxide, clindamycin, benzoyl peroxide with salicylic acid, and combination benzoyl peroxide/clindamycin in acne. J Am Acad Dermatol. 2010;63:52-62 pubmed publisher
    Comparative efficacy of the multiple treatments containing benzoyl peroxide (BPO) and clindamycin (CL) is not established. We compared the efficacy of topical 5% BPO, 1% to 1...
  22. Lamont R, Nhan Chang C, Sobel J, Workowski K, Conde Agudelo A, Romero R. Treatment of abnormal vaginal flora in early pregnancy with clindamycin for the prevention of spontaneous preterm birth: a systematic review and metaanalysis. Am J Obstet Gynecol. 2011;205:177-90 pubmed publisher
    The purpose of this study was to determine whether the administration of clindamycin to women with abnormal vaginal flora at <22 weeks of gestation reduces the risk of preterm birth and late miscarriage...
  23. Grinwis M, Sibley C, Parkins M, Eshaghurshan C, Rabin H, Surette M. Macrolide and clindamycin resistance in Streptococcus milleri group isolates from the airways of cystic fibrosis patients. Antimicrob Agents Chemother. 2010;54:2823-9 pubmed publisher
    ..However, more than half of the CF isolates were not susceptible to azithromycin, erythromycin, and clindamycin, compared to 11%, 13%, and 6.5% of invasive isolates, respectively...
  24. Buffie C, Jarchum I, Equinda M, Lipuma L, Gobourne A, Viale A, et al. Profound alterations of intestinal microbiota following a single dose of clindamycin results in sustained susceptibility to Clostridium difficile-induced colitis. Infect Immun. 2012;80:62-73 pubmed publisher
    ..b>Clindamycin predisposes patients to C. difficile colitis...
  25. Bradshaw C, Pirotta M, De Guingand D, Hocking J, Morton A, Garland S, et al. Efficacy of oral metronidazole with vaginal clindamycin or vaginal probiotic for bacterial vaginosis: randomised placebo-controlled double-blind trial. PLoS ONE. 2012;7:e34540 pubmed publisher
    To determine if oral metronidazole (MTZ-400 mg bid) with 2% vaginal clindamycin-cream (Clind) or a Lactobacillus acidophilus vaginal-probiotic containing oestriol (Prob) reduces 6-month bacterial vaginosis (BV) recurrence...
  26. Qin X, Poon B, Kwong J, Niles D, Schmidt B, Rajagopal L, et al. Two paediatric cases of skin and soft-tissue infections due to clindamycin-resistant Staphylococcus aureus carrying a plasmid-encoded vga(A) allelic variant for a putative efflux pump. Int J Antimicrob Agents. 2011;38:81-3 pubmed publisher
    ..e. erythromycin-susceptible but clindamycin-resistant...
  27. Chen A, Carroll K, Diener West M, Ross T, Ordun J, Goldstein M, et al. Randomized controlled trial of cephalexin versus clindamycin for uncomplicated pediatric skin infections. Pediatrics. 2011;127:e573-80 pubmed publisher
    To compare clindamycin and cephalexin for treatment of uncomplicated skin and soft tissue infections (SSTIs) caused predominantly by community-associated (CA) methicillin-resistant Staphylococcus aureus (MRSA)...
  28. Katopodis G, Grivea I, Tsantsaridou A, Pournaras S, Petinaki E, Syrogiannopoulos G. Fusidic acid and clindamycin resistance in community-associated, methicillin-resistant Staphylococcus aureus infections in children of Central Greece. BMC Infect Dis. 2010;10:351 pubmed publisher
    In Greece, fusidic acid and clindamycin are commonly used for the empiric therapy of suspected staphylococcal infections...
  29. Lavallée C, Rouleau D, Gaudreau C, Roger M, Tsimiklis C, Locas M, et al. Performance of an agar dilution method and a Vitek 2 card for detection of inducible clindamycin resistance in Staphylococcus spp. J Clin Microbiol. 2010;48:1354-7 pubmed publisher
    The D-zone test detects inducible clindamycin resistance in Staphylococcus spp...
  30. Seitz C, Brocker E, Trautmann A. Allergy diagnostic testing in clindamycin-induced skin reactions. Int Arch Allergy Immunol. 2009;149:246-50 pubmed publisher
    In clinical practice, clindamycin is increasingly used because of its good tolerability and high efficacy with excellent tissue penetration...
  31. Ruangweerayut R, Looareesuwan S, Hutchinson D, Chauemung A, Banmairuroi V, Na Bangchang K. Assessment of the pharmacokinetics and dynamics of two combination regimens of fosmidomycin-clindamycin in patients with acute uncomplicated falciparum malaria. Malar J. 2008;7:225 pubmed publisher
    This study investigated the pharmacokinetics of fosmidomycin when given in combination with clindamycin at two dosage regimens in patients with acute uncomplicated falciparum malaria...
  32. Singh K, Murray B. Differences in the Enterococcus faecalis lsa locus that influence susceptibility to quinupristin-dalfopristin and clindamycin. Antimicrob Agents Chemother. 2005;49:32-9 pubmed
    ..lsa gene, encoding the putative ABC protein Lsa, influences resistance to quinupristin-dalfopristin (Q-D) and clindamycin (CLI). We have now found that, while cloned lsa from E...
  33. Gadepalli R, Dhawan B, Mohanty S, Kapil A, Das B, Chaudhry R. Inducible clindamycin resistance in clinical isolates of Staphylococcus aureus. Indian J Med Res. 2006;123:571-3 pubmed
  34. Han L, McDougal L, Gorwitz R, Mayer K, Patel J, Sennott J, et al. High frequencies of clindamycin and tetracycline resistance in methicillin-resistant Staphylococcus aureus pulsed-field type USA300 isolates collected at a Boston ambulatory health center. J Clin Microbiol. 2007;45:1350-2 pubmed
    Individual or multiple resistance to clindamycin, tetracycline, erythromycin, levofloxacin, or mupirocin was detected in a large proportion of methicillin-resistant Staphylococcus aureus pulsed-field type USA300 isolates collected at an ..
  35. Yilmaz G, Aydin K, Iskender S, Caylan R, Koksal I. Detection and prevalence of inducible clindamycin resistance in staphylococci. J Med Microbiol. 2007;56:342-5 pubmed
    ..The resistance to antimicrobial agents among staphylococci is an increasing problem. Clindamycin (CL) is considered to be one of the alternative agents in these infections...
  36. Deluyker H, Van Oye S, Boucher J. Factors affecting cure and somatic cell count after pirlimycin treatment of subclinical mastitis in lactating cows. J Dairy Sci. 2005;88:604-14 pubmed
    ..Posttreatment SCC was associated with treatment regimen, other risk factors, and interactions among the other risk factors; but these other risk factors did not vary significantly with treatment regimen. ..
  37. Gold M, Rao J, Goldman M, Bridges T, Bradshaw V, Boring M, et al. A multicenter clinical evaluation of the treatment of mild to moderate inflammatory acne vulgaris of the face with visible blue light in comparison to topical 1% clindamycin antibiotic solution. J Drugs Dermatol. 2005;4:64-70 pubmed
    ..blue light source in the treatment of mild to moderate inflammatory acne vulgaris in comparison to topical 1% clindamycin solution...
  38. Nyirjesy P, McIntosh M, Steinmetz J, Schumacher R, Joffrion J. The effects of intravaginal clindamycin and metronidazole therapy on vaginal mobiluncus morphotypes in patients with bacterial vaginosis. Sex Transm Dis. 2007;34:197-202 pubmed
    ..The objective of this study was to compare the effects of treatments for bacterial vaginosis (BV) on vaginal Mobiluncus morphotypes...
  39. Pattavilakom A, Xenos C, Bradfield O, Danks R. Reduction in shunt infection using antibiotic impregnated CSF shunt catheters: an Australian prospective study. J Clin Neurosci. 2007;14:526-31 pubmed
    ..We present our prospective evaluation of the efficacy of antibiotic (rifampicin and clindamycin) impregnated cerebrospinal fluid (CSF) shunt catheters (AIC) in a mixed paediatric and adult Australian ..
  40. Ugwumadu A, Reid F, Hay P, Manyonda I. Natural history of bacterial vaginosis and intermediate flora in pregnancy and effect of oral clindamycin. Obstet Gynecol. 2004;104:114-9 pubmed
    ..sought to describe the natural history of abnormal vaginal flora in pregnancy and estimate the efficacy of oral clindamycin in eradicating it and preventing relapse...
  41. Nyberg S, Osterblad M, Hakanen A, Lofmark S, Edlund C, Huovinen P, et al. Long-term antimicrobial resistance in Escherichia coli from human intestinal microbiota after administration of clindamycin. Scand J Infect Dis. 2007;39:514-20 pubmed
    ..Four subjects had received 150 mg clindamycin perorally for 7 d, while 4 non-exposed subjects served as a control group...
  42. Aygun C, Kocaman O, Gurbuz Y, Senturk O, Hulagu S. Clindamycin-induced acute cholestatic hepatitis. World J Gastroenterol. 2007;13:5408-10 pubmed
    We report a case of acute hepatotoxicity in a 42-year-old woman after administration of clindamycin for a dental infection. After 6 d of treatment, she had fatigue, nausea, vomiting, anorexia, pruritus and jaundice...
  43. Guay D. Topical clindamycin in the management of acne vulgaris. Expert Opin Pharmacother. 2007;8:2625-64 pubmed
    ..These include oral tetracycline, doxycycline, minocycline and topical clindamycin and erythromycin...
  44. Eymann R, Steudel W, Kiefer M. Infection rate with application of an antibiotic-impregnated catheter for shunt implantation in children - a retrospective analysis. Klin Padiatr. 2009;221:69-73 pubmed publisher
    ..Apparently, AIS can reduce the incidence of shunt infections in children. Further prospective trials with a larger cohort are necessary for a statistically significant prove. ..
  45. Ritz R, Roser F, Morgalla M, Dietz K, Tatagiba M, Will B. Do antibiotic-impregnated shunts in hydrocephalus therapy reduce the risk of infection? An observational study in 258 patients. BMC Infect Dis. 2007;7:38 pubmed
    ..In 86 patients AIS systems were implanted. Shunt catheters were commercially impregnated with clindamycin and rifampicin...
  46. Sobrin L, Kump L, Foster C. Intravitreal clindamycin for toxoplasmic retinochoroiditis. Retina. 2007;27:952-7 pubmed
    To report outcomes of off-label use of intravitreal clindamycin in the treatment of toxoplasmic retinochoroiditis...
  47. Diz Dios P, Tomás Carmona I, Limeres Posse J, Medina Henriquez J, Fernandez Feijoo J, Alvarez Fernandez M. Comparative efficacies of amoxicillin, clindamycin, and moxifloxacin in prevention of bacteremia following dental extractions. Antimicrob Agents Chemother. 2006;50:2996-3002 pubmed
    We evaluated the efficacies of oral prophylactic treatment with amoxicillin (AMX), clindamycin (CLI), and moxifloxacin (MXF) in the prevention of bacteremia following dental extractions (BDE)...
  48. LaPlante K, Leonard S, Andes D, Craig W, Rybak M. Activities of clindamycin, daptomycin, doxycycline, linezolid, trimethoprim-sulfamethoxazole, and vancomycin against community-associated methicillin-resistant Staphylococcus aureus with inducible clindamycin resistance in murine thigh infection and . Antimicrob Agents Chemother. 2008;52:2156-62 pubmed publisher
    ..Staphylococcus aureus (CA-MRSA) and about the ability of these strains to develop inducible resistance to clindamycin during therapy...
  49. Delialioglu N, Aslan G, Ozturk C, Baki V, Sen S, Emekdas G. Inducible clindamycin resistance in staphylococci isolated from clinical samples. Jpn J Infect Dis. 2005;58:104-6 pubmed
    ..The double-disc test was applied by placing erythromycin and clindamycin discs on these isolates to investigate the inducible and constitutive MLS(B) resistance phenotypes and MS ..
  50. Tanghetti E, Kircik L, Wilson D, Dhawan S. Solubilized benzoyl peroxide versus benzoyl peroxide/clindamycin in the treatment of moderate acne. J Drugs Dermatol. 2008;7:534-8 pubmed
    ..acne vulgaris were randomly assigned to receive solubilized BPO 5% gel on one side of the face and a BPO 5%/clindamycin 1% combination product on the contralateral side, twice daily for 4 weeks...
  51. Kim J, Choi J, Park J, Kim J, Jin S, Chang S, et al. Development of clindamycin-loaded wound dressing with polyvinyl alcohol and sodium alginate. Biol Pharm Bull. 2008;31:2277-82 pubmed
    To develop a clindamycin-loaded wound dressing, cross-linked hydrogel films were prepared using freeze-thawing method with various mixtures of polyvinyl alcohol (PVA) and sodium alginate (SA)...
  52. Desjardins M, Delgaty K, Ramotar K, Seetaram C, Toye B. Prevalence and mechanisms of erythromycin resistance in group A and group B Streptococcus: implications for reporting susceptibility results. J Clin Microbiol. 2004;42:5620-3 pubmed
    ..Cross-resistance to clindamycin may be present, depending on the mechanism of resistance...
  53. Acikgoz Z, Almayanlar E, Gamberzade S, Gocer S. Macrolide resistance determinants of invasive and noninvasive group B streptococci in a Turkish hospital. Antimicrob Agents Chemother. 2004;48:1410-2 pubmed
    ..The genes responsible were erm(B), erm(A) subclass erm(TR), and erm(B) plus erm(TR) in 62.9, 2.9, and 8.6% of isolates, respectively. Nine isolates (25.7%) harbored neither mef nor detectable erm genes. ..