sufentanil

Summary

Summary: An opioid analgesic that is used as an adjunct in anesthesia, in balanced anesthesia, and as a primary anesthetic agent.

Top Publications

  1. Casati A, Fanelli G, Albertin A, Deni F, Danelli G, Grifoni F, et al. Small doses of remifentanil or sufentanil for blunting cardiovascular changes induced by tracheal intubation: a double-blind comparison. Eur J Anaesthesiol. 2001;18:108-12 pubmed
    ..the effects on cardiovascular changes induced by tracheal intubation when small doses of either remifentanil or sufentanil are used in the presence of midazolam...
  2. Braga A, Braga F, Potério G, Pereira R, Reis E, Cremonesi E. Sufentanil added to hyperbaric bupivacaine for subarachnoid block in Caesarean section. Eur J Anaesthesiol. 2003;20:631-5 pubmed
    ..We studied the quality of the block and its maternal-fetal repercussions when different doses of sufentanil were combined with hyperbaric bupivacaine using the intrathecal route in pregnant women undergoing Caesarean ..
  3. Coleman L, Carvalho B, Lipman S, Schmiesing C, Riley E. Accidental intrathecal sufentanil overdose during combined spinal-epidural analgesia for labor. Int J Obstet Anesth. 2009;18:78-80 pubmed publisher
    A laboring woman was accidentally given 45 microg of sufentanil intrathecally in the course of combined spinal-epidural analgesia...
  4. Wang L, Chang X, Liu X, Hu X, Tang B. Comparison of bupivacaine, ropivacaine and levobupivacaine with sufentanil for patient-controlled epidural analgesia during labor: a randomized clinical trial. Chin Med J (Engl). 2010;123:178-83 pubmed
    ..1%, 0.125% or 0.15% of either bupivacaine (Group B), ropivacaine (Group R) or levobupivacaine (Group L) with sufentanil 0.5 microg/ml was epidurally administered by patient-controlled analgesia mode...
  5. Zhang C, Ma W, Yang Y, Dong F, Wang H, Wei H. Effect of the intraoperative wake-up test in sevoflurane-sufentanil combined anesthesia during adolescent idiopathic scoliosis surgery: a randomized study. J Clin Anesth. 2013;25:263-7 pubmed publisher
    To investigate the effect of the intraoperative wake-up test on sevoflurane-sufentanil anesthesia for adolescent idiopathic scoliosis (AIS) surgery.
  6. Safavi M, Honarmand A. Attenuation of cardiovascular responses to laryngoscopy and tracheal intubation--intravenous sufentanil vs pethidine. Middle East J Anaesthesiol. 2008;19:1349-59 pubmed
    The study was undertaken to compare the effects of small doses of sufentanil or pethidine on cardiovascular responses induced by tracheal intubation...
  7. Soulard A, Babre F, Bordes M, Meymat Y, Sztark F, Cros A. Optimal dose of sufentanil in children for intubation after sevoflurane induction without neuromuscular block. Br J Anaesth. 2009;102:680-5 pubmed publisher
    We studied 63 ASA I children (age 2-8 yr) to determine the sufentanil dose needed to facilitate intubation under excellent conditions after inhalation induction with various end-tidal concentrations of sevoflurane without neuromuscular ..
  8. Qian X, Chen X, Li D. Low-dose ropivacaine-sufentanil spinal anaesthesia for caesarean delivery: a randomised trial. Int J Obstet Anesth. 2008;17:309-14 pubmed publisher
    ..The aim of this study was to evaluate whether low-dose ropivacaine in combination with sufentanil could produce effective spinal anaesthesia with less maternal hypotension and vomiting than ropivacaine alone...
  9. Dewandre P, Decurninge V, Bonhomme V, Hans P, Brichant J. Side effects of the addition of clonidine 75 microg or sufentanil 5 microg to 0.2% ropivacaine for labour epidural analgesia. Int J Obstet Anesth. 2010;19:149-54 pubmed publisher
    b>Sufentanil 5 microg and clonidine 75 microg produce a similar reduction in minimum local anaesthetic concentration of ropivacaine. The aim of the present study was to compare the side effects of two equianalgesic solutions by combining 0...

More Information

Publications62

  1. Lili X, Zhiyong H, Jianjun S. Asleep-awake-asleep technique in children during strabismus surgery under sufentanil balanced anesthesia. Paediatr Anaesth. 2012;22:1216-20 pubmed publisher
    ..by means of target-controlled infusions (TCI) of propofol and remifentanil propofol compared with propofol and sufentanil. Forty-six ASA I-II patients undergoing strabismus surgery with intraoperative awakening were randomly assigned ..
  2. Zhang G, Sun L. Peri-intubation hemodynamic changes during low dose fentanyl, remifentanil and sufentanil combined with etomidate for anesthetic induction. Chin Med J (Engl). 2009;122:2330-4 pubmed
    ..randomized, double-blinded study was designed to investigate the effects of low dose remifentanil, fentanyl or sufentanil on etomidate induction with respect to hemodynamics, conscious level changes and drug consumption...
  3. Wandel C, Kim R, Wood M, Wood A. Interaction of morphine, fentanyl, sufentanil, alfentanil, and loperamide with the efflux drug transporter P-glycoprotein. Anesthesiology. 2002;96:913-20 pubmed
    ..In this study, the authors examined whether other opioids of importance to anesthesiologists such as fentanyl, sufentanil, and alfentanil, and also morphine-6-glucuronide and morphine-3-glucuronide, are P-glycoprotein substrates and ..
  4. Minkowitz H, Singla N, Evashenk M, Hwang S, Chiang Y, Hamel L, et al. Pharmacokinetics of sublingual sufentanil tablets and efficacy and safety in the management of postoperative pain. Reg Anesth Pain Med. 2013;38:131-9 pubmed publisher
    A sublingual sufentanil tablet is being developed as a potential alternative to intravenous (IV) opioids for the management of postoperative pain...
  5. Kamphuis E, Kuipers P, van Venrooij G, Kalkman C. The effects of spinal anesthesia with lidocaine and sufentanil on lower urinary tract functions. Anesth Analg. 2008;107:2073-8 pubmed publisher
    ..We studied the effects of spinal anesthesia with a combination of lidocaine and sufentanil on lower urinary tract function...
  6. Lilker S, Rofaeel A, Balki M, Carvalho J. Comparison of fentanyl and sufentanil as adjuncts to bupivacaine for labor epidural analgesia. J Clin Anesth. 2009;21:108-12 pubmed publisher
    To compare the clinical efficacy of theoretically equipotent doses of fentanyl and sufentanil, each in combination with bupivacaine, for patient-controlled epidural analgesia (PCEA) for labor. Single-blinded, randomized study...
  7. Liao X, Yang Q, Xue F, Luo M, Xu Y, Liu Y, et al. Bolus dose remifentanil and sufentanil blunting cardiovascular intubation responses in children: a randomized, double-blind comparison. Eur J Anaesthesiol. 2009;26:73-80 pubmed publisher
    The present randomized controlled study was designed to compare the efficacy of remifentanil 2 microg kg(-1) and sufentanil 0.2 microg kg(-1) by bolus injection on the cardiovascular response to intubation in healthy children...
  8. Korak Leiter M, Likar R, Oher M, Trampitsch E, Ziervogel G, Levy J, et al. Withdrawal following sufentanil/propofol and sufentanil/midazolam. Sedation in surgical ICU patients: correlation with central nervous parameters and endogenous opioids. Intensive Care Med. 2005;31:380-7 pubmed
    ..Following sufentanil/midazolam (group 1; n =14) or sufentanil/propofol (group 2; n =15) sedation, patients were evaluated for changes ..
  9. Mendola C, Ferrante D, Oldani E, Cammarota G, Cecci G, Vaschetto R, et al. Thoracic epidural analgesia in post-thoracotomy patients: comparison of three different concentrations of levobupivacaine and sufentanil. Br J Anaesth. 2009;102:418-23 pubmed publisher
    ..in patients admitted for thoracic surgery during continuous thoracic epidural infusion using levobupivacaine and sufentanil mixture in three different volumes...
  10. Höcker J, Weber B, Tonner P, Scholz J, Brand P, Ohnesorge H, et al. Meperidine, remifentanil and tramadol but not sufentanil interact with alpha(2)-adrenoceptors in alpha(2A)-, alpha(2B)- and alpha(2C)-adrenoceptor knock out mice brain. Eur J Pharmacol. 2008;582:70-7 pubmed publisher
    ..The authors therefore studied the ability of four different opioids (meperidine, remifentanil, sufentanil and tramadol) to interact with different alpha(2)-adrenoceptor subtypes in mice lacking individual alpha(2A)-, ..
  11. Glenski J, Friesen R, Hassanein R, Henry D. Comparison of the hemodynamic and echocardiographic effects of sufentanil, fentanyl, isoflurane, and halothane for pediatric cardiovascular surgery. J Cardiothorac Anesth. 1988;2:147-55 pubmed
    b>Sufentanil, fentanyl, halothane, and isoflurane were compared as sole anesthetic agents in 48 infants and children aged 6 months to 9 years, undergoing repair of congenital heart defects...
  12. Roelants F, Lavand homme P. Epidural neostigmine combined with sufentanil provides balanced and selective analgesia in early labor. Anesthesiology. 2004;101:439-44 pubmed
    This study evaluated the efficacy of an epidural single dose of neostigmine combined with sufentanil to provide selective and balanced analgesia at the beginning of labor.
  13. Boselli E, Debon R, Cimino Y, Rimmelé T, Allaouchiche B, Chassard D. Background infusion is not beneficial during labor patient-controlled analgesia with 0.1% ropivacaine plus 0.5 microg/ml sufentanil. Anesthesiology. 2004;100:968-72 pubmed
    ..1% ropivacaine plus 0.5 microg/ml sufentanil were randomly assigned to four groups, according to the rate of background infusion used (0, 3, 6, and 9 ml/h)...
  14. Roelants F, Rizzo M, Lavand homme P. The effect of epidural neostigmine combined with ropivacaine and sufentanil on neuraxial analgesia during labor. Anesth Analg. 2003;96:1161-6, table of contents pubmed
    ..1%, with and without sufentanil 10 microg, to initiate analgesia...
  15. Kim S, Cho J, Hong J, Koo B, Kim J, Kil H. Comparison of intrathecal fentanyl and sufentanil in low-dose dilute bupivacaine spinal anaesthesia for transurethral prostatectomy. Br J Anaesth. 2009;103:750-4 pubmed publisher
    ..We aimed at comparing the efficacy of intrathecal fentanyl and sufentanil with low-dose diluted bupivacaine for transurethral prostatectomy (TURP) in elderly patients...
  16. Lilot M, Meuret P, Bouvet L, Caruso L, Dabouz R, Deléat Besson R, et al. Hypobaric spinal anesthesia with ropivacaine plus sufentanil for traumatic femoral neck surgery in the elderly: a dose-response study. Anesth Analg. 2013;117:259-64 pubmed publisher
    In this randomized, prospective trial, we sought to determine the effective dose of hypobaric ropivacaine with sufentanil providing 95% success (ED95) in spinal anesthesia for traumatic femoral neck surgery in the elderly...
  17. Bachmann Mennenga B, Veit G, Steinicke B, Biscoping J, Heesen M. Efficacy of sufentanil addition to ropivacaine epidural anaesthesia for Caesarean section. Acta Anaesthesiol Scand. 2005;49:532-7 pubmed
    This prospective double-blind trial evaluated the effect of sufentanil addition to epidural ropivacaine for elective Caesarean section...
  18. Memis D, Turan A, Karamanlioglu B, Oguzhan N, Pamukcu Z. Comparison of sufentanil with sufentanil plus magnesium sulphate for sedation in the intensive care unit using bispectral index. Crit Care. 2003;7:R123-8 pubmed
    ..using bispectral index (BIS) monitoring, whether the addition of magnesium sulphate infusion could decrease the sufentanil infusion required to maintain sedation...
  19. Wappler F, Scholz J, Prause A, Möllenberg O, Bause H, Schulte Am Esch J. [Level concept of analgesic dosing in intensive care medicine with sufentanil]. Anasthesiol Intensivmed Notfallmed Schmerzther. 1998;33:8-26 pubmed
    ..Level 1 consisted of continuous administration of sufentanil, in level 2 continuous administration of midazolam and level 3 continuous administration of midazolam and ..
  20. Benson G, Thurmon J, Tranquilli W, Corbin J. Intravenous administration of lenperone and glycopyrrolate followed by continuous infusion of sufentanil in dogs: cardiovascular effects. Am J Vet Res. 1987;48:1372-5 pubmed
    ..11 mg/kg) were determined in 6 healthy adult (2 to 5 years) Pointers during controlled ventilation with oxygen. Sufentanil was then administered as a loading dose (5 micrograms/kg, IV) and continually infused (0...
  21. Putensen C, Zech S, Wrigge H, Zinserling J, Stuber F, von Spiegel T, et al. Long-term effects of spontaneous breathing during ventilatory support in patients with acute lung injury. Am J Respir Crit Care Med. 2001;164:43-9 pubmed
    ..Patients maintained spontaneous breathing during APRV with continuous infusion of sufentanil and midazolam (Ramsay sedation score [RSS] of 3)...
  22. Prause A, Wappler F, Scholz J, Bause H, Schulte Am Esch J. Respiratory depression under long-term sedation with sufentanil, midazolam and clonidine has no clinical significance. Intensive Care Med. 2000;26:1454-61 pubmed
    Assessment of respiratory depression caused by long-term sedation with sufentanil, midazolam and clonidine. Retrospective assessment using data from a patient data management system. University hospital anaesthesiological ICU...
  23. Standl T, Horn E, Luckmann M, Burmeister M, Wilhelm S, Schulte Am Esch J. Subarachnoid sufentanil for early postoperative pain management in orthopedic patients: a placebo-controlled, double-blind study using spinal microcatheters. Anesthesiology. 2001;94:230-8 pubmed
    ..Eighty patients randomly received a subarachnoid injection of 10 microg sufentanil, 5 mg bupivacaine, 2.5 microg sufentanil plus 2...
  24. Lysakowski C, Dumont L, Pellegrini M, Clergue F, Tassonyi E. Effects of fentanyl, alfentanil, remifentanil and sufentanil on loss of consciousness and bispectral index during propofol induction of anaesthesia. Br J Anaesth. 2001;86:523-7 pubmed
    ..used to determine and compare the effect of propofol in the presence of fentanyl, alfentanil, remifentanil and sufentanil. Seventy-five non-premedicated patients were assigned randomly into five groups (15 in each) to receive fentanyl,..
  25. D Angelo R, Dean L, Meister G, Nelson K. Neostigmine combined with bupivacaine, clonidine, and sufentanil for spinal labor analgesia. Anesth Analg. 2001;93:1560-4, table of contents pubmed
    We previously found that spinal clonidine prolongs labor analgesia when combined with spinal bupivacaine and sufentanil. We sought to determine whether the addition of spinal neostigmine to these drugs would further enhance labor ..
  26. Lecomte P, Ouattara A, Le Manach Y, Landi M, Coriat P, Riou B. The coronary and myocardial effects of remifentanil and sufentanil in the erythrocyte-perfused isolated rabbit heart. Anesth Analg. 2006;103:9-14, table of contents pubmed
    ..rabbit model and compared these effects with those provoked by similar intracoronary concentrations of sufentanil. Under general anesthesia, hearts from New Zealand rabbits were rapidly excised and mounted on an erythrocyte-..
  27. Boselli E, Allaouchiche B, Chassard D. Comparison of continuous background infusion plus demand dose and demand-only parturient-controlled epidural analgesia (PCEA) using ropivacaine combined with sufentanil for labor and delivery. Int J Obstet Anesth. 2006;15:86; author reply 87 pubmed
  28. Schmidt B, Adelmann C, Stutzer H, Welzing L, Hünseler C, Kribs A, et al. Comparison of sufentanil versus fentanyl in ventilated term neonates. Klin Padiatr. 2010;222:62-6 pubmed publisher
    ..In a double-blind randomized trial 20 newborns received a continuous intravenous infusion of fentanyl (n=10) or sufentanil (n=10) in an assumed equipotent dose of 7:1...
  29. Hutchins J, Leiman D, Minkowitz H, Jove M, Didonato K, Palmer P. An Open-Label Study of Sufentanil Sublingual Tablet 30?Mcg in Patients with Postoperative Pain. Pain Med. 2017;: pubmed publisher
    To evaluate sufentanil sublingual tablet 30?mcg (SST 30?mcg) for postoperative pain in an older patient population with comorbidities.
  30. Flier S, Post J, Concepcion A, Kappen T, Kalkman C, Buhre W. Influence of propofol-opioid vs isoflurane-opioid anaesthesia on postoperative troponin release in patients undergoing coronary artery bypass grafting. Br J Anaesth. 2010;105:122-30 pubmed publisher
    ..We therefore compared isoflurane-sufentanil vs propofol-sufentanil anaesthesia in patients undergoing coronary artery bypass grafting...
  31. De Baerdemaeker L, Jacobs S, Pattyn P, Mortier E, Struys M. Influence of intraoperative opioid on postoperative pain and pulmonary function after laparoscopic gastric banding: remifentanil TCI vs sufentanil TCI in morbid obesity. Br J Anaesth. 2007;99:404-11 pubmed
    ..The aim of this study was to compare the effects of target-controlled infusions (TCIs) of remifentanil or sufentanil on postoperative analgesia, recovery, and pulmonary function after laparoscopic gastric banding...
  32. Zhang H, Yang Y, Guo Q. [Comparison of clinical effect of sufentanil and fentanyl during heart value replacement surgery]. Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2005;30:238-40 pubmed
  33. Eilers K, Schenk M, Putzier M, Volk T, Kox W, Zippel H. [Use of peridural catheters in the treatment of postoperative pain after spinal instrumentated fusion--an experience report]. Z Orthop Ihre Grenzgeb. 2002;140:621-5 pubmed
    ..For epidural catheter analgesia a mixture of the local anesthetic ropivacaine and the opioid sufentanil was used with an initial bolus, followed by a continuous infusion and the possibility of patient-controlled ..
  34. Grosso P, D Urso L, Collura D, Citro R, Grassano M, Macchiarulo R, et al. Transrectal-HIFU as primary minimally-invasive option for localized prostate cancer. Is spinal anaesthesia cost-effective? A single centre experience in over 100 patients. Arch Ital Urol Androl. 2009;81:13-6 pubmed
    ..5% normobaric racemic bupivacaine (15 to 17.5 mg) and sufentanil 5 microg...
  35. Madi Jebara S, Adaimé C, Yazigi A, Haddad F, Hayek G, Sleilaty G, et al. [Thoracic epidural and intrathecal analgesia have similar effects on pain relief and respiratory function after thoracic surgery]. Can J Anaesth. 2005;52:710-6 pubmed
    ..the effects of thoracic epidural infusions of fentanyl (F) and bupivacaine (B) to intrathecal morphine (M) and sufentanil (S) on analgesia and respiratory function following thoracotomy...
  36. Walter U, Brüderlein U, Gloger M, Mann S, Walther U. [Brain death diagnosis after sedation with propofol or sufentanil. Recommendations for the usage of toxicological analytics]. Med Klin Intensivmed Notfmed. 2015;110:145-9 pubmed publisher
    ..For propofol and sufentanil there are no uniform recommendations for the usage of toxicology test results...
  37. Liu N, Gintzler A. Spinal endomorphin 2 antinociception and the mechanisms that produce it are both sex- and stage of estrus cycle-dependent in rats. J Pain. 2013;14:1522-30 pubmed publisher
    ..for neither spinal EM2 antinociception in males nor the antinociception elicited in proestrus females by spinal sufentanil or [d-Ala(2),N-methyl-Phe(4),Gly-ol(5)]-enkephalin, which are prototypic MOR-selective nonpeptide and peptide ..
  38. Evron S, Ezri T. Options for systemic labor analgesia. Curr Opin Anaesthesiol. 2007;20:181-5 pubmed
    ..Recently, their efficacy has been questioned. Patient-controlled intravenous analgesia with fentanyl or sufentanil is currently the method of choice for achieving analgesia during early labor, when epidural analgesia is not ..
  39. Sui J, Liu X, Deng X, Tang G, Wei L, Yang D, et al. [Application of conscious sedation with midazolam, propofol and sufentanil for patients in plastic surgery]. Zhonghua Zheng Xing Wai Ke Za Zhi. 2012;28:278-81 pubmed
    To observe the effectiveness of conscious sedation with midazolam, propofol and sufentanil for patients in plastic surgery. 81 patients, scheduled for plastic surgery, were randomly selected to receive conscious sedation with midazolam 0...
  40. Manola M, De Luca E, Moscillo L, Mastella A. Using remifentanil and sufentanil in functional endoscopic sinus surgery to improve surgical conditions. ORL J Otorhinolaryngol Relat Spec. 2005;67:83-6 pubmed
    ..The patients were divided into three groups according to the type of anesthesia they had: group A (sufentanil/sevoflurane), group B (remifentanil/propofol), and group C (fentanyl/isoflurane)...
  41. Tuncer S, Bariskaner H, Yosunkaya A, Kilic M, Dogan N, Otelcioglu S. [The effects of sufentanil and remifentanil in the isolated perfused rat kidney]. Agri. 2004;16:56-61 pubmed
    ..NO synthetase inhibitor) and naloxane (nonselective opioid receptor antagonists) on the responses induced by sufentanil and remifentanil were investigated in the isolated perfused rat kidney. Renal arter was cannulated...
  42. Li J, Huang Z, Zhang X, Luo K, Zhang Z, Mao Y, et al. Sufentanil reduces emergence agitation in children receiving sevoflurane anesthesia for adenotonsillectomy compared with fentanyl. Chin Med J (Engl). 2011;124:3682-5 pubmed
    ..The purpose of this study was to investigate the effect of sufentanil to reduce emergence agitation after sevoflurane anesthesia in children undergoing adenotonsillectomy compared ..
  43. Chaveron D, Silva S, Sanchez Verlaan P, Conil J, Sommet A, Geeraerts T, et al. The 90% effective dose of a sufentanil bolus for the management of painful positioning in intubated patients in the ICU. Eur J Anaesthesiol. 2012;29:280-5 pubmed publisher
    ..by bolus administration could permit lower background infusion rates, but the lowest effective bolus dose of sufentanil to achieve this is unknown...
  44. Yuan R, Zhang X, Deng Q, Wu Y, Xiang G. Impact of CYP3A4*1G polymorphism on metabolism of fentanyl in Chinese patients undergoing lower abdominal surgery. Clin Chim Acta. 2011;412:755-60 pubmed publisher
    ..The specific CYP3A4*1G polymorphism may predict the individual requirement of fentanyl. ..
  45. Volobuef C, Moraes C, Nunes L, Cereda C, Yokaichiya F, Franco M, et al. Sufentanil-2-hydroxypropyl-?-cyclodextrin inclusion complex for pain treatment: physicochemical, cytotoxicity, and pharmacological evaluation. J Pharm Sci. 2012;101:3698-707 pubmed publisher
    b>Sufentanil (SUF) is a synthetic analgesic opioid widely used for the management of acute and chronic pain...
  46. Jung S, Yang C, Oh J, Cho C, Kang P, Lim Y, et al. Predicted effect-site concentration of propofol and sufentanil for gynecological laparoscopic surgery. Acta Anaesthesiol Scand. 2011;55:110-7 pubmed publisher
    ..0, 2.5, 3.0, 3.5 and 4.0 microg/ml during TCI with propofol and sufentanil. The dose-response relationship of propofol for the maintenance of adequate anesthesia based on BIS, movement ..
  47. Kim J, Lee S, Koo B, Noh S, Kil H, Kim H, et al. The effect of epidural sufentanil in ropivacaine on urinary retention in patients undergoing gastrectomy. Br J Anaesth. 2006;97:414-8 pubmed
    ..This study was designed to compare side-effects of epidural sufentanil in ropivacaine with that of morphine in ropivacaine focusing on lower urinary tract function after major ..
  48. Lele A, Ziai W. Target-controlled infusion for sedation of traumatic brain-injured patients: role uncertain. Crit Care Med. 2005;33:1172-4 pubmed
  49. De Monte V, Staffieri F, Caivano D, Bufalari A. Anaesthetic management for balloon dilation of cor triatriatum dexter in a dog. Acta Vet Scand. 2015;57:29 pubmed publisher
    ..The dog was premedicated with 0.5 μg/kg sufentanil and 0.2 mg/kg midazolam administered intravenously...
  50. Zhang Y, Zhang L, Gu E, Zhu B, Zhao X, Chen J. Long-term insulin treatment restores cardioprotection induced by sufentanil postconditioning in diabetic rat heart. Exp Biol Med (Maywood). 2016;241:650-7 pubmed publisher
    b>Sufentanil, a commonly used opioid analgesic, could mimic ischemia postconditioning to attenuate ischemia reperfusion injury, but this effect might be hindered in diabetic animals by inhibition of glycogen synthase kinase-3β ..
  51. Necib S, Tubach F, Peuch C, Lebihan E, Samain E, Mantz J, et al. Recovery from anesthesia after craniotomy for supratentorial tumors: comparison of propofol-remifentanil and sevoflurane-sufentanil (the PROMIFLUNIL trial). J Neurosurg Anesthesiol. 2014;26:37-44 pubmed publisher
    ..The aim of this study was to compare the recovery of 2 Bispectral index (BIS)-guided anesthesia protocols combining sevoflurane-sufentanil (SS) or propofol-remifentanil (PR) administered during craniotomy for STT.
  52. Akural E, Salomäki T, Tekay A, Bloigu A, Alahuhta S. Pre-emptive effect of epidural sufentanil in abdominal hysterectomy. Br J Anaesth. 2002;88:803-8 pubmed
    ..patients undergoing abdominal hysterectomy were allocated randomly in a double-blind fashion to receive sufentanil 50 micrograms via a lumbar epidural catheter before or at the end of surgery...
  53. Neuhäuser C, Muller M, Welters I, Scholz S, Kwapisz M. Effect of isoflurane on echocardiographic left-ventricular relaxation indices in patients with diastolic dysfunction due to concentric hypertrophy and ischemic heart disease. J Cardiothorac Vasc Anesth. 2006;20:509-14 pubmed
    ..After approval of the local ethics committee and informed consent, patients randomly received sufentanil/midazolam anesthesia plus either 0.5 to 1...