miconazole

Summary

Summary: An imidazole antifungal agent that is used topically and by intravenous infusion.

Top Publications

  1. Isham N, Ghannoum M. Antifungal activity of miconazole against recent Candida strains. Mycoses. 2010;53:434-7 pubmed publisher
    b>Miconazole (MICON) has long been used for the topical treatment of mucosal candidiasis...
  2. Cerdeira A, Mazzotti M, Gander B. Formulation and drying of miconazole and itraconazole nanosuspensions. Int J Pharm. 2013;443:209-20 pubmed publisher
    b>Miconazole and itraconazole possess adequate membrane permeability, but only slight water solubility, which limits their bioavailability and antifungal effect...
  3. Repiso Montero T, Lopez S, Rodriguez C, del Rio R, Badell A, Gratacós M. Eberconazole 1% cream is an effective and safe alternative for dermatophytosis treatment: multicenter, randomized, double-blind, comparative trial with miconazole 2% cream. Int J Dermatol. 2006;45:600-4 pubmed
    ..The purpose of this trial was to evaluate the efficacy of eberconazole 1% cream compared with miconazole 2% cream in the treatment of dermatophytoses...
  4. Ozyurt E, Toykuliyeva M, Danilyans I, Morton O, Baktir G. Efficacy of 7-day treatment with metronidazole+miconazole (Neo-Penotran) - a triple-active pessary for the treatment of single and mixed vaginal infections. Int J Gynaecol Obstet. 2001;74:35-43 pubmed
    To evaluate the efficacy of Neo-Penotran pessaries (metronidazole 500 mg + miconazole nitrate 100 mg) in candidal, bacterial and trichomonal vaginitis and in mixed vaginal infections...
  5. Amanlou M, Beitollahi J, Abdollahzadeh S, Tohidast Ekrad Z. Miconazole gel compared with Zataria multiflora Boiss. gel in the treatment of denture stomatitis. Phytother Res. 2006;20:966-9 pubmed
    An open, randomized, controlled study with two parallel treatment groups was done to evaluate the efficacy of a miconazole 2% gel compared with Zataria multiflora 0...
  6. Nava Ortiz C, Burillo G, Concheiro A, Bucio E, Matthijs N, Nelis H, et al. Cyclodextrin-functionalized biomaterials loaded with miconazole prevent Candida albicans biofilm formation in vitro. Acta Biomater. 2010;6:1398-404 pubmed publisher
    ..functionalization with CDs provided PE and PP with the capability to incorporate the anti-fungal drug miconazole (up to 0.27 mg cm(-2)), leading to reduced biofilm formation by C. albicans in an in vitro biofilm model system...
  7. Menon S, Izquierdo A, Rosen M, Hummel A, Barnhart K. The effect of ambulation on vaginal distribution of miconazole nitrate (1200 mg). J Womens Health (Larchmt). 2007;16:703-6 pubmed
    To evaluate the effect activity has on the vaginal distribution of a 1200 mg miconazole nitrate gelatin encapsulated insert, an antifungal agent commonly used to treat vaginal vulvocandidiasis...
  8. Kikuchi K, Nagatomo T, Abe H, Kawakami K, Duff H, Makielski J, et al. Blockade of HERG cardiac K+ current by antifungal drug miconazole. Br J Pharmacol. 2005;144:840-8 pubmed
    1. Miconazole, an imidazole antifungal agent, is associated with acquired long QT syndrome and ventricular arrhythmias...
  9. Bensadoun R, Daoud J, El Gueddari B, Bastit L, Gourmet R, Rosikon A, et al. Comparison of the efficacy and safety of miconazole 50-mg mucoadhesive buccal tablets with miconazole 500-mg gel in the treatment of oropharyngeal candidiasis: a prospective, randomized, single-blind, multicenter, comparative, phase III trial in pati. Cancer. 2008;112:204-11 pubmed
    ..b>Miconazole Lauriad 50-mg mucoadhesive buccal tablet (MBT) Loramyc reportedly delivered rapid and prolonged, effective ..

More Information

Publications62

  1. Kobayashi D, Kondo K, Uehara N, Otokozawa S, Tsuji N, Yagihashi A, et al. Endogenous reactive oxygen species is an important mediator of miconazole antifungal effect. Antimicrob Agents Chemother. 2002;46:3113-7 pubmed
    We investigated the significance of endogenous reactive oxygen species (ROS) produced by fungi treated with miconazole. ROS production in Candida albicans was measured by a real-time fluorogenic assay...
  2. Barillaro V, Bertholet P, Henry de Hassonville S, Ziemon E, Evrard B, Delattre L, et al. Effect of acidic ternary compounds on the formation of miconazole/cyclodextrin inclusion complexes by means of supercritical carbon dioxide. J Pharm Pharm Sci. 2004;7:378-88 pubmed
    The aim of the study is to evaluate the effect of different acidic compounds on the inclusion of miconazole (MICO) in several cyclodextrins (CDs) using supercritical carbon dioxide (SCCO(2) ) processing...
  3. Fukuda T, Hasegawa Y, Sakabe Y, Tomoda H, Omura S. Citrinamides, new potentiators of antifungal miconazole activity, produced by Penicillium sp. FKI-1938. J Antibiot (Tokyo). 2008;61:550-5 pubmed publisher
    ..Their structures were elucidated by spectroscopic analysis, including NMR and amino acid analysis. Citrinamides A and B showed moderate potentiation of miconazole activity against Candida albicans.
  4. Gonçalves A, Viana J, Pires E, Boia M, Coura J, Silva E. The use of the antifungal agent miconazole as an inhibitor of Blastocystis hominis growth in Entamoeba histolytica/E. dispar cultures. Rev Inst Med Trop Sao Paulo. 2007;49:201-2 pubmed
    ..The present study reports on the excellent efficacy (100%) of the antifungal agent miconazole in eliminating B. hominis from cultures of E. histolytica/E...
  5. Aboul Enein H, Ali I. Comparison of the chiral resolution of econazole, miconazole, and sulconazole by HPLC using normal-phase amylose CSPs. Fresenius J Anal Chem. 2001;370:951-5 pubmed
    Resolution of the enantiomers of (+/-)-econazole, (+/-)-miconazole, and (+/-)-sulconazole has been achieved on different normal-phase chiral amylose columns, Chi-ralpak AD, AS, and AR...
  6. Pietschmann S, Hoffmann K, Voget M, Pison U. Synergistic effects of miconazole and polymyxin B on microbial pathogens. Vet Res Commun. 2009;33:489-505 pubmed publisher
    ..To assess the value of an antibiotic combination of polymyxin B and miconazole this study examined the in vitro synergistic potential of the two drugs on Gram-negative and Gram-positive ..
  7. Urban V, Seo R, Giannini M, Arrais C. Superficial distribution and identification of antifungal/antimicrobial agents on a modified tissue conditioner by SEM-EDS microanalysis: a preliminary study. J Prosthodont. 2009;18:603-10 pubmed publisher
    ..Skokie, IL) powder were 500,000 U (G1) and 1,000,000 U (G2). The addition of miconazole was at 125 mg (G3) and 250 mg (G4), and ketoconazole was at 100 mg (G5) and 200 mg (G6)...
  8. Vazquez J, Patton L, Epstein J, Ramlachan P, Mitha I, Noveljic Z, et al. Randomized, comparative, double-blind, double-dummy, multicenter trial of miconazole buccal tablet and clotrimazole troches for the treatment of oropharyngeal candidiasis: study of miconazole Lauriad® efficacy and safety (SMiLES). HIV Clin Trials. 2010;11:186-96 pubmed publisher
    ..Once-daily miconazole 50 mg buccal tablet (MBT) is a novel delivery system using an extended-spectrum azole with potent in vitro ..
  9. Bink A, Vandenbosch D, Coenye T, Nelis H, Cammue B, Thevissen K. Superoxide dismutases are involved in Candida albicans biofilm persistence against miconazole. Antimicrob Agents Chemother. 2011;55:4033-7 pubmed publisher
    We investigated the cellular mechanisms responsible for the occurrence of miconazole-tolerant persisters in Candida albicans biofilms. Miconazole induced about 30% killing of sessile C. albicans cells at 75 ?M...
  10. Concannon P, Gisoldi E, Phillips S, Grossman R. Diaper dermatitis: a therapeutic dilemma. Results of a double-blind placebo controlled trial of miconazole nitrate 0.25%. Pediatr Dermatol. 2001;18:149-55 pubmed
    ..This placebo-controlled, randomized, double-blind, parallel-group trial compared the efficacy and safety of miconazole nitrate 0...
  11. Carbone M, Conrotto D, Carrozzo M, Broccoletti R, Gandolfo S, Scully C. Topical corticosteroids in association with miconazole and chlorhexidine in the long-term management of atrophic-erosive oral lichen planus: a placebo-controlled and comparative study between clobetasol and fluocinonide. Oral Dis. 1999;5:44-9 pubmed
    ..in an adhesive medium (4% hydroxyethyl cellulose gel) plus in each case antimycotic treatment consisting of miconazole gel and 0.12% chlorhexidine mouthwashes...
  12. Cerdeira A, Mazzotti M, Gander B. Miconazole nanosuspensions: Influence of formulation variables on particle size reduction and physical stability. Int J Pharm. 2010;396:210-8 pubmed publisher
    ..In this study, the practically water-insoluble miconazole was nanoground, and a variety of surface active and polymeric excipients were tested for their stabilizing ..
  13. Wei G, Xu X, Wu C. In vitro synergism between berberine and miconazole against planktonic and biofilm Candida cultures. Arch Oral Biol. 2011;56:565-72 pubmed publisher
    ..The minimum inhibitory concentrations (MICs) of BBR, miconazole (MCZ), and fluconazole (FLC) towards Candida albicans, Candida glabrata, Candida kefyr, Candida krusei, Candida ..
  14. Kovac M, Mitic G, Kovac Z. Miconazole and nystatin used as topical antifungal drugs interact equally strongly with warfarin. J Clin Pharm Ther. 2012;37:45-8 pubmed publisher
    Medline search disclosed 10 case reports of interactions between oral anticoagulants and miconazole oral gel, but none so far between nystatin solution and anticoagulants...
  15. Lubet R, Steele V, Eto I, Juliana M, Kelloff G, Grubbs C. Chemopreventive efficacy of anethole trithione, N-acetyl-L-cysteine, miconazole and phenethylisothiocyanate in the DMBA-induced rat mammary cancer model. Int J Cancer. 1997;72:95-101 pubmed
    The chemopreventive efficacy of N-acetyl-L-cysteine (NAC), anethole trithione, miconazole and phenethylisothiocyanate (PEITC), each of which would be expected to alter carcinogen metabolism, was examined in the dimethylbenzanthracene (..
  16. Vandenbosch D, De Canck E, Dhondt I, Rigole P, Nelis H, Coenye T. Genomewide screening for genes involved in biofilm formation and miconazole susceptibility in Saccharomyces cerevisiae. FEMS Yeast Res. 2013;13:720-30 pubmed publisher
    ..Previous research has shown that 1-10% of sessile Candida cells survive treatment with high doses of miconazole (a fungicidal imidazole)...
  17. Lorente L, Lecuona M, Ramos M, Jimenez A, Mora M, Sierra A. The use of rifampicin-miconazole-impregnated catheters reduces the incidence of femoral and jugular catheter-related bacteremia. Clin Infect Dis. 2008;47:1171-5 pubmed publisher
    ..study was to determine the incidence of central venous catheter-related bacteremia associated with rifampicin-miconazole-impregnated catheters and standard catheters in patients with femoral and central jugular venous accesses...
  18. Sharma A, Saple D, Surjushe A, Rao G, Kura M, Ghosh S, et al. Efficacy and tolerability of sertaconazole nitrate 2% cream vs. miconazole in patients with cutaneous dermatophytosis. Mycoses. 2011;54:217-22 pubmed publisher
    Sertaconazole is a new antifungal agent. To compare the efficacy and tolerability of sertaconazole and miconazole cream in cutaneous dermatophytosis, this prospective, randomized, multicentric comparative, phase 4 study was undertaken in ..
  19. Peixoto F, Camargos A, Duarte G, Linhares I, Bahamondes L, Petracco A. Efficacy and tolerance of metronidazole and miconazole nitrate in treatment of vaginitis. Int J Gynaecol Obstet. 2008;102:287-92 pubmed publisher
    To evaluate the efficacy and tolerability of a vaginal pessary containing 750 mg of metronidazole and 200 mg of miconazole nitrate used daily for 7 days in the treatment of vaginitis.
  20. Boyen F, Verstappen K, De Bock M, Duim B, Weese J, Schwarz S, et al. In vitro antimicrobial activity of miconazole and polymyxin B against canine meticillin-resistant Staphylococcus aureus and meticillin-resistant Staphylococcus pseudintermedius isolates. Vet Dermatol. 2012;23:381-5, e70 pubmed publisher
    ..Meticillin-resistant Staphylococcus aureus (MRSA) and meticillin-resistant Staphylococcus pseudintermedius (MRSP) infections are increasingly reported in dogs, and these bacteria may be isolated from ear infections...
  21. Fothergill A. Miconazole: a historical perspective. Expert Rev Anti Infect Ther. 2006;4:171-5 pubmed
    b>Miconazole is an imidazole that has been successfully used for over 30 years for the treatment of superficial and cutaneous disease. This agent is distinguished from other azoles by possessing two mechanisms of action...
  22. Warshaw E, St Clair K. Prevention of onychomycosis reinfection for patients with complete cure of all 10 toenails: results of a double-blind, placebo-controlled, pilot study of prophylactic miconazole powder 2%. J Am Acad Dermatol. 2005;53:717-20 pubmed
    ..double-blind, placebo-controlled, randomized trial involving 48 participants was to determine if biweekly miconazole powder prevents onychomycosis recurrence...
  23. Nafee N, Ismail F, Boraie N, Mortada L. Mucoadhesive buccal patches of miconazole nitrate: in vitro/in vivo performance and effect of ageing. Int J Pharm. 2003;264:1-14 pubmed
    Mucoadhesive patches containing 10mg miconazole nitrate were evaluated...
  24. Jernerén F, Oliw E. The fatty acid 8,11-diol synthase of Aspergillus fumigatus is inhibited by imidazole derivatives and unrelated to PpoB. Lipids. 2012;47:707-17 pubmed publisher
    ..The 8,11-diol synthase was soluble and had a larger molecular size (>100 kDa) than most P450. Miconazole, ketoconazole, and 1-benzylimidazole, classical inhibitors of P450, reduced the biosynthesis of 8,11-DiHODE from ..
  25. Huang A, Sun D, Wu Z, Yan C, Carroll M, Jiang H, et al. Estrogen elicits cytochrome P450--mediated flow-induced dilation of arterioles in NO deficiency: role of PI3K-Akt phosphorylation in genomic regulation. Circ Res. 2004;94:245-52 pubmed
    ..Dilations of these vessels, however, were eliminated by PPOH and miconazole, inhibitors of CYP/epoxygenase...
  26. Landowski C, Bolanz K, Suzuki Y, Hediger M. Chemical inhibitors of the calcium entry channel TRPV6. Pharm Res. 2011;28:322-30 pubmed publisher
    ..4 ?M). These results suggest that compound #03 is a relatively selective and potent inhibitor for TRPV6 and that it is an interesting lead compound for the treatment of prostate cancer and other cancers of epithelial origin. ..
  27. Paolo W, Dadachova E, Mandal P, Casadevall A, Szaniszlo P, Nosanchuk J. Effects of disrupting the polyketide synthase gene WdPKS1 in Wangiella [Exophiala] dermatitidis on melanin production and resistance to killing by antifungal compounds, enzymatic degradation, and extremes in temperature. BMC Microbiol. 2006;6:55 pubmed
    ..The biological role of the WdPKS-independent melanin remains unclear. ..
  28. Simonetti G, Baffa S, Simonetti N. Contact imidazole activity against resistant bacteria and fungi. Int J Antimicrob Agents. 2001;17:389-93 pubmed
    The activities of miconazole and miconazole sulphosalicylate were evaluated by a contact test using strains of Enterococcus faecalis and Escherichia coli and Candida spp selected for their resistance...
  29. De la Torre J, Ortiz Samperio M, Marcos Arias C, Marichalar Mendia X, Eraso E, Echebarría Goicouría M, et al. In Vitro Antifungal Susceptibility of Oral Candida Isolates from Patients Suffering from Caries and Chronic Periodontitis. Mycopathologia. 2017;182:471-485 pubmed publisher
    ..In vitro activities of amphotericin B, fluconazole, itraconazole, miconazole, nystatin, posaconazole and voriconazole against 126 oral Candida isolates (75 Candida albicans, 18 Candida ..
  30. Falk S, Noah J, Weisblum B. Screen for inducers of autolysis in Bacillus subtilis. Antimicrob Agents Chemother. 2010;54:3723-9 pubmed publisher
    ..quot; Thus, the screen independently identified the potential antibacterial properties of the antifungal drug miconazole and of the antileishmaniasis drug miltefosine...
  31. Heeres J, Meerpoel L, Lewi P. Conazoles. Molecules. 2010;15:4129-88 pubmed publisher
    This review provides a historical overview of the analog based drug discovery of miconazole and its congeners, and is focused on marketed azole antifungals bearing the generic suffix "conazole"...
  32. Imagawa K, Fang Y, Sugiura R, Zhou X, Ma Y, Kuno T. Isolation of a fission yeast mutant cell affected in MAP kinase signaling and sterol biosynthesis. Kobe J Med Sci. 2009;55:E30-5 pubmed
    ..Consistently, the vic6 mutant cells exhibited hypersensitivity to miconazole, an inhibitor of ergosterol biosynthesis and showed aberrant intracellular localization of filipin, suggesting ..
  33. El Ahmed H, Cañadas De la Fuente G, Fernández Castillo R, González Jiménez E, Cantero Hinojosa J, Lardón Fernández M. [Generalized cutaneous candidiasis in newborn at term]. Biomedica. 2012;32:170-3 pubmed publisher
    ..Blood culture was positive for Staphylococcus aureus. Cutaneous biopsy confirmed the cutaneous candidiasis. The early diagnosis is essential to prevent complications derived by the Candida albicans in newborns. ..
  34. Zagorac D, Jakovcevic D, Gebremedhin D, Harder D. Antiangiogenic effect of inhibitors of cytochrome P450 on rats with glioblastoma multiforme. J Cereb Blood Flow Metab. 2008;28:1431-9 pubmed publisher
    ..Two mechanistically different inhibitors of CYP epoxygenase, 17-octadecynoic acid (17-ODYA) and miconazole, significantly reduced capillary formation and tumor size in glial tumors formed by injection of rat glioma 2 (..
  35. Baird J, Santiago Quinonez D, Rinaldi C, Taylor L. Role of viscosity in influencing the glass-forming ability of organic molecules from the undercooled melt state. Pharm Res. 2012;29:271-84 pubmed publisher
    ..The objective of this study was to investigate potential links between viscosity and crystallization tendency for organic compounds from the undercooled melt state...
  36. Thevissen K, Ayscough K, Aerts A, Du W, De Brucker K, Meert E, et al. Miconazole induces changes in actin cytoskeleton prior to reactive oxygen species induction in yeast. J Biol Chem. 2007;282:21592-7 pubmed
    The antifungal compound miconazole inhibits ergosterol biosynthesis and induces reactive oxygen species (ROS) in susceptible yeast species...
  37. Francois I, Bink A, Vandercappellen J, Ayscough K, Toulmay A, Schneiter R, et al. Membrane rafts are involved in intracellular miconazole accumulation in yeast cells. J Biol Chem. 2009;284:32680-5 pubmed publisher
    ..We demonstrated previously that miconazole induces actin cytoskeleton stabilization in Saccharomyces cerevisiae prior to induction of reactive oxygen ..
  38. Nagata M. [Malassezia and its presumed association with skin diseases in dogs]. Med Mycol J. 2013;54:45-7 pubmed
    ..The clinical features suggest that it corresponds to seborrheic dermatitis in humans. Hence, it might be possible to identify essential pathogenesis of the disease by clarifying its differences in humans and animals as a shared disease. ..
  39. Ben Slama L, Hasni W. [Miconazole in gingival muco-adhesive tablet (Loramyc 50mg)]. Rev Stomatol Chir Maxillofac. 2008;109:197-200 pubmed publisher
  40. Barasch A, Griffin A. Miconazole revisited: new evidence of antifungal efficacy from laboratory and clinical trials. Future Microbiol. 2008;3:265-9 pubmed publisher
    ..However, the discovery of an additional fungicidal mode of action for miconazole has drawn renewed attention to this compound...
  41. Grönlund J, Saari T, Hagelberg N, Neuvonen P, Olkkola K, Laine K. Miconazole oral gel increases exposure to oral oxycodone by inhibition of CYP2D6 and CYP3A4. Antimicrob Agents Chemother. 2011;55:1063-7 pubmed publisher
    Our aim was to assess the effect of miconazole oral gel on the pharmacokinetics of oral oxycodone...
  42. Vandenbosch D, Bink A, Govaert G, Cammue B, Nelis H, Thevissen K, et al. Phytosphingosine-1-phosphate is a signaling molecule involved in miconazole resistance in sessile Candida albicans cells. Antimicrob Agents Chemother. 2012;56:2290-4 pubmed publisher
    Previous research has shown that 1% to 10% of sessile Candida albicans cells survive treatment with high doses of miconazole (a fungicidal imidazole)...
  43. Alcântara C, Macêdo A, Gurgel B, Jorge J, Neppelenbroek K, Urban V. Peel bond strength of resilient liner modified by the addition of antimicrobial agents to denture base acrylic resin. J Appl Oral Sci. 2012;20:607-12 pubmed
    ..The drug powder concentrations (nystatin 500,000 U--G2; nystatin 1,000,000 U--G3; miconazole 125 mg--G4; miconazole 250 mg--G5; ketoconazole 100 mg - G6; ketoconazole 200 mg--G7; chlorhexidine diacetate 5%-..
  44. Carradori S, Bizzarri B, D Ascenzio M, De Monte C, Grande R, Rivanera D, et al. Synthesis, biological evaluation and quantitative structure-active relationships of 1,3-thiazolidin-4-one derivatives. A promising chemical scaffold endowed with high antifungal potency and low cytotoxicity. Eur J Med Chem. 2017;140:274-292 pubmed publisher
    ..e. clotrimazole, fluconazole, ketoconazole, miconazole, tioconazole, amphotericin B)...
  45. Baptista G, Eiden C, Monguillot P, Philibert C, Jeandel C. Serotonin syndrome during treatment with low dose of escitalopram associated with miconazole mucoadhesive tablet: a suspected drug interaction. Int Psychogeriatr. 2012;24:845-7 pubmed publisher
    ..The onset of this episode could have been induced by a drug-drug interaction with an acute treatment by miconazole gingival adhesive tablets...
  46. Ashikawa Y, Nishimura Y, Okabe S, Sasagawa S, Murakami S, Yuge M, et al. Activation of Sterol Regulatory Element Binding Factors by Fenofibrate and Gemfibrozil Stimulates Myelination in Zebrafish. Front Pharmacol. 2016;7:206 pubmed publisher
    ..In this study, we performed comparative transcriptome analysis to identify pharmacodynamic effects common to miconazole and clobetasol, which have been shown to stimulate myelination by mouse oligodendrocyte progenitor cells (OPCs)...
  47. Barillaro V, Dive G, Ziemons E, Bertholet P, Evrard B, Delattre L, et al. Theoretical and experimental vibrational study of miconazole and its dimers with organic acids: application to the IR characterization of its inclusion complexes with cyclodextrins. Int J Pharm. 2008;350:155-65 pubmed
    The geometry, frequency and intensity of the vibrational bands of miconazole were derived from the density functional theory (DFT) calculations with the hybrid functional B3LYP and the 6-31G(d) basis set...
  48. Bull J, Balskus E, Horan R, Langner M, Ley S. Stereocontrolled total synthesis of bengazole a: a marine bisoxazole natural product displaying potent antifungal properties. Angew Chem Int Ed Engl. 2006;45:6714-8 pubmed
  49. LaFleur M, Sun L, Lister I, Keating J, Nantel A, Long L, et al. Potentiation of azole antifungals by 2-adamantanamine. Antimicrob Agents Chemother. 2013;57:3585-92 pubmed publisher
    ..2-Adamantanamine (AC17) was identified in a screen for compounds potentiating the action of miconazole against biofilms of Candida albicans...
  50. Gerova M, Kittova M. Systemic blood pressure response to the inhibition of two hyperpolarizing pathways: a comparison to NO-synthase inhibition. Physiol Res. 2006;55:603-10 pubmed
    ..blood pressure, after inhibitory intervention in arachidonic acid metabolism cytochrome P-450 inhibition by miconazole 0.5 mg/100 g b.w. , one of the hyperpolarizing pathways, did not change...
  51. Miller K, Al Rayyan N, Ivanova M, Mattingly K, Ripp S, Klinge C, et al. DHEA metabolites activate estrogen receptors alpha and beta. Steroids. 2013;78:15-25 pubmed publisher
    ..ER antagonists ICI 182,780 (fulvestrant) and 4-hydroxytamoxifen, general P450 inhibitor miconazole, and aromatase inhibitor exemestane inhibited activation by DHEA or metabolites in transfected cells...
  52. Lepelley M, Logerot S, Fonrose X, Villier C. [Pharmacokinetic drug interaction between miconazole mucoadhesive tablet and tacrolimus: About 3 case-reports in transplant patients]. Therapie. 2017;72:475-482 pubmed publisher
    Loramyc® is a mucoadhesive tablet of miconazole, indicated for the treatment of oropharyngeal candidiasis in immunocompromised patients...
  53. How K, Tang M, Kaur R, Johar A. Contact sensitisation in adults: a 5-year retrospective review in hospital Kuala Lumpur. Med J Malaysia. 2017;72:113-118 pubmed
    ..9%), stannous chloride (18/85, 21.2%), miconazole (7/44, 15.9%), gold(I)sodium thiosulfate (16/105, 15.2%) and thimerosal (29/202, 14.4%)...