plasmacytoma

Summary

Summary: Any discrete, presumably solitary, mass of neoplastic PLASMA CELLS either in BONE MARROW or various extramedullary sites.

Top Publications

  1. Dores G, Landgren O, McGlynn K, Curtis R, Linet M, Devesa S. Plasmacytoma of bone, extramedullary plasmacytoma, and multiple myeloma: incidence and survival in the United States, 1992-2004. Br J Haematol. 2009;144:86-94 pubmed publisher
    Population-based plasmacytoma incidence and survival data are sparse...
  2. Salazar Onfray F, Charo J, Petersson M, Freland S, Noffz G, Qin Z, et al. Down-regulation of the expression and function of the transporter associated with antigen processing in murine tumor cell lines expressing IL-10. J Immunol. 1997;159:3195-202 pubmed
    ..In the J558L plasmacytoma cell line, constitutively expressing high levels of IL-10, increased TAP-dependent translocation of peptides ..
  3. Kanzawa M, Hirai C, Morinaga Y, Kawakami F, Hara S, Matsuoka H, et al. Primary submucosal nodular plasmacytoma of the stomach: a poorly recognized variant of gastric lymphoma. Diagn Pathol. 2013;8:30 pubmed publisher
    Gastric plasmacytoma (GP) is a rare variant of gastric lymphomas. In the exceptional event that a patient presents with GP, the lesion occupies the mucosal layer in the vast majority of cases...
  4. Gupta P, Rice G, Abraham K, Ghole V, Ketkar M. Extramedullary plasmacytoma of the pancreas and jejunum. Clin Imaging. 2009;33:240-3 pubmed publisher
    Plasmacytomas occurring in the gastrointestinal tract are extremely rare. We report one such case of pancreatic and jejunal plasmacytoma in a single patient with known multiple myeloma with emphasis on computed tomographic (CT) findings.
  5. Pasch W, Zhao X, Rezk S. Solitary plasmacytoma of the bone involving young individuals, is there a role for preceding trauma?. Int J Clin Exp Pathol. 2012;5:463-7 pubmed
    Solitary plasmacytoma of the bone (SPB) is a rare plasma cell neoplasm that usually presents as a lytic lesion mainly localized within the axial skeleton...
  6. Schaefer T, Vorhees C, Williams M. Mouse plasmacytoma-expressed transcript 1 knock out induced 5-HT disruption results in a lack of cognitive deficits and an anxiety phenotype complicated by hypoactivity and defensiveness. Neuroscience. 2009;164:1431-43 pubmed publisher
    ..Lack of differences may be the result of compensatory mechanisms in reaction to a constitutive knock out of Pet-1 or 5-HT may not be as important in learning and memory as previously suspected...
  7. Zidar N, Zver S, Jurcić V. Extraosseus plasmacytoma of the pharynx with localized light chain deposition. Case report. Pathol Oncol Res. 2010;16:249-52 pubmed publisher
    ..an isolated form of LCDD, which was limited to the pharyngeal mucosa and was associated with an extraosseus plasmacytoma of the pharynx, expanding the spectrum that has been recognized for LCDD...
  8. Guo S, Zhi Y, Yang H, Yu Y, Wang Y, Zhang J, et al. Bcl-2 expression is associated with poor prognosis of solitary plasmacytoma of bone. Ann Hematol. 2014;93:471-7 pubmed publisher
    Solitary plasmacytoma of bone (SPB) is a rare tumor that represents a minority of patients with plasma cell localized malignancy characterized by a single osteolytic bone lesion...
  9. Atiq M, Ali S, Dang S, Krishna S, Anaisse E, Olden K, et al. Pancreatic plasmacytoma presenting as variceal hemorrhage: life threatening complication of a rare entity. JOP. 2009;10:187-8 pubmed
    Pancreatic plasmacytoma is a rare entity and presents with features of mass lesion of pancreas.

More Information

Publications74

  1. Mimura R, Kamishima T, Kubota K, Nakano F, Yabe I, Sasaki H, et al. Extramedullary plasmacytoma involving perirenal space accompanied by extramedullary hematopoiesis and amyloid deposition. Jpn J Radiol. 2010;28:309-13 pubmed publisher
    ..Pathological diagnosis of the biopsy specimen was extramedullary plasmacytoma accompanied by extramedullary hematopoiesis and amyloid deposition...
  2. Mu B, Yang J, Gou L, Yao Y, Zhou Y, Cheng Z, et al. Polyclonal rabbit anti-murine plasmacytoma cell globulins induce myeloma cells apoptosis and inhibit tumour growth in mice. Apoptosis. 2011;16:370-81 pubmed publisher
    ..In this study, we produced polyclonal rabbit anti-murine plasmacytoma cell immunoglobulin (PAb) by immunizing rabbits with the murine plasmacytoma cell line MPC-11...
  3. Morariu I, Burns P, Roche P, Hone S. Triple manifestation of extramedullary plasmacytoma in the upper airway: an unusual clinical entity. J Laryngol Otol. 2011;125:970-2 pubmed publisher
    We report an extremely rare case of extramedullary plasmacytoma.
  4. Santos V, Brito E, Paz B, Leal C. Rib plasmacytoma and IgA multiple myeloma with hyperviscosity syndrome. Arch Iran Med. 2012;15:517-9 pubmed publisher
    Solitary bone plasmacytoma (SPB) can progress to generalized myeloma if not treated early. The elderly population is increasing and delays in diagnosis of plasma cell malignancies are frequent among them...
  5. González Guijarro I, Díez González L, Rodriguez Acevedo N, Pallas Pallas E. [Extramedullary plasmacytoma of the larynx. A case report]. Acta Otorrinolaringol Esp. 2011;62:320-2 pubmed publisher
    Extramedullary plasmacytoma of the larynx and localized laryngeal amyloidosis are two entities that are extremely rare in children...
  6. Ueda K, Matsui H, Watanabe T, Seki J, Ichinohe T, Tsuji Y, et al. Spontaneous rupture of liver plasmacytoma mimicking hepatocellular carcinoma. Intern Med. 2010;49:653-7 pubmed
    Extramedullary plasmacytoma of the liver is rare. Here, we report a case presenting with rupture of extramedullary plasmacytoma of the liver. She had a past history of multiple myeloma with IgA lambda type...
  7. Kilciksiz S, Karakoyun Celik O, Agaoglu F, Haydaroglu A. A review for solitary plasmacytoma of bone and extramedullary plasmacytoma. ScientificWorldJournal. 2012;2012:895765 pubmed publisher
    Solitary plasmacytoma (SP) is characterized by a mass of neoplastic monoclonal plasma cells in either bone (SBP) or soft tissue without evidence of systemic disease attributing to myeloma...
  8. Sakai Y, Ikeya J, Morita I, Sato K. Extramedullary plasmacytoma of the tonsil diagnosed by fine-needle aspiration cytology. Ann Diagn Pathol. 2008;12:41-3 pubmed publisher
    A case of tonsillar extramedullary plasmacytoma in a 53-year-old man with a complaint of lump sensation in the throat is presented. Examination of the oral cavity showed enlargement of the left tonsil...
  9. Suh Y, Suh C, Kim J, Kim S, Pyun H, Cho J. Radiotherapy for solitary plasmacytoma of bone and soft tissue: outcomes and prognostic factors. Ann Hematol. 2012;91:1785-93 pubmed publisher
    We investigated treatment outcomes of radiotherapy for solitary plasmacytoma (SP) and prognostic factors affecting survival...
  10. Liu H, Luo X, Zhou S, Zheng Z. Prognosis and expression of lambda light chains in solitary extramedullary plasmacytoma of the head and neck: two case reports and a literature review. J Int Med Res. 2010;38:282-8 pubmed
    Two cases of extramedullary plasmacytoma (EMP) of the head and neck, an uncommon plasma cell neoplasm, were studied. Both patients had good outcomes and have been followed for 17 and 12 years without recurrence or systemic disease...
  11. Yu S, Chen S, Lu W, Liu T, Lin C. Expression of CD19 and lack of miR-223 distinguish extramedullary plasmacytoma from multiple myeloma. Histopathology. 2011;58:896-905 pubmed publisher
    Extramedullary plasmacytoma (EMP) and multiple myeloma (MM) are both plasma cell (PC) tumours that are usually distinguished by clinical manifestations, but not by histopathological examination alone...
  12. He M, Zhu M, Zhang Y, Fu Q, Wu L. [Solitary plasmacytoma of spine: a clinical, radiologic and pathologic study of 13 cases]. Zhonghua Bing Li Xue Za Zhi. 2009;38:307-11 pubmed
    To study the clinical, radiologic and pathologic features of solitary plasmacytoma of spine.
  13. Creach K, Foote R, Neben Wittich M, Kyle R. Radiotherapy for extramedullary plasmacytoma of the head and neck. Int J Radiat Oncol Biol Phys. 2009;73:789-94 pubmed publisher
    To define the effectiveness of radiotherapy in the treatment of patients with extramedullary plasmacytoma of the head and neck (EMPHN).
  14. Turk H, Komurcu S, Ozet A, Kuzhan O, Gunhan O. An unusual presentation of extramedullary plasmacytoma in testis and review of the literature. Med Oncol. 2010;27:1378-80 pubmed publisher
    Extramedullary plasmacytoma is a rare plasma cell neoplasm, and it is extremely uncommon in the testicles. We report a 73-year-old man with multiple myeloma presented with testicular plasmacytoma...
  15. Iseri M, Ozturk M, Ulubil S. Synchronous presentation of extramedullary plasmacytoma in the nasopharynx and the larynx. Ear Nose Throat J. 2009;88:E9-12 pubmed
    Simultaneous extramedullary plasmacytoma of the nasopharynx and larynx is exceedingly rare; to the best of our knowledge, only 1 other case has been previously reported. We report a new case, which occurred in a 46-year-old woman...
  16. Richendollar B, Hsi E, Cook J. Extramedullary plasmacytoma-like posttransplantation lymphoproliferative disorders: clinical and pathologic features. Am J Clin Pathol. 2009;132:581-8 pubmed publisher
    ..This report describes the clinical, histologic, phenotypic, and genotypic findings in 4 cases of plasmacytoma-like PTLD (2 nodal, 1 adenoidal, and 1 cutaneous) and compares the findings with extramedullary involvement by ..
  17. Kotani Y, Ito M, Abumi K, Yasui K, Minami A. Neurological recovery from pentaplegia after resection for sacral plasmacytoma presenting with POEMS syndrome. J Neurosurg Spine. 2009;10:324-8 pubmed publisher
    ..developed with neurological respiratory failure due to POEMS syndrome associated with a solitary sacral plasmacytoma. Resection was finally performed after her condition proved resistant to radiation and chemotherapy...
  18. Dimopoulos M, Terpos E, Comenzo R, Tosi P, Beksac M, Sezer O, et al. International myeloma working group consensus statement and guidelines regarding the current role of imaging techniques in the diagnosis and monitoring of multiple Myeloma. Leukemia. 2009;23:1545-56 pubmed publisher
    ..recommended in MM patients with normal conventional radiography and in all patients with an apparently solitary plasmacytoma of bone...
  19. Kilciksiz S, Celik O, Pak Y, Demiral A, Pehlivan M, Orhan O, et al. Clinical and prognostic features of plasmacytomas: a multicenter study of Turkish Oncology Group-Sarcoma Working Party. Am J Hematol. 2008;83:702-7 pubmed publisher
    To identify the outcomes of prognostic factors of solitary plasmacytoma mainly treated with local radiotherapy (RT). The data were collected from 80 patients with solitary plasmacytoma (SP). Forty patients (50...
  20. Pan S, Wan Hitam W, Mohd Noor R, Bhavaraju V. Recurrence of multiple myeloma with soft tissue plasmacytoma presenting as unilateral proptosis. Orbit. 2011;30:105-7 pubmed publisher
    To describe a rare case of soft tissue plasmacytoma of the orbit presenting with proptosis.
  21. Shao H, Xi L, Raffeld M, Pittaluga S, Dunleavy K, Wilson W, et al. Nodal and extranodal plasmacytomas expressing immunoglobulin a: an indolent lymphoproliferative disorder with a low risk of clinical progression. Am J Surg Pathol. 2010;34:1425-35 pubmed publisher
    ..In this study, 9 cases of IgA-positive plasmacytoma presenting in lymph node and 3 in extranodal sites were analyzed by morphology, immunohistochemistry, and ..
  22. Bink K, Haralambieva E, Kremer M, Ott G, Beham Schmid C, de Leval L, et al. Primary extramedullary plasmacytoma: similarities with and differences from multiple myeloma revealed by interphase cytogenetics. Haematologica. 2008;93:623-6 pubmed publisher
    Primary extramedullary plasmacytoma is an indolent neoplasm that infrequently converts to multiple myeloma...
  23. Kawasaki N, Nakada K, Kawasaki Y, Suzuki Y, Masuda K, Miyazawa Y, et al. Primary gastric plasmacytoma refractory to Helicobacter pylori eradication therapy. Dig Endosc. 2009;21:37-9 pubmed publisher
    ..Immunohistochemically, plasma cells were positive for lambda-chain. Primary gastric plasmacytoma was diagnosed. Total gastrectomy was carried out with splenectomy and regional lymph node dissection...
  24. Qing X, Sun N, Chang E, French S, Ji P, Yue C. Plasmablastic lymphoma may occur as a high-grade transformation from plasmacytoma. Exp Mol Pathol. 2011;90:85-90 pubmed publisher
    ..chain restriction, but without EBER expression, raising the possibility of a preexisting or concurrent plasmacytoma and that the PBL may be a high-grade transformation from a preexisting plasma cell neoplasm following Epstein-..
  25. Shin D, Shaffer D, Wang H, Roopenian D, Morse H. NOTCH is part of the transcriptional network regulating cell growth and survival in mouse plasmacytomas. Cancer Res. 2008;68:9202-11 pubmed publisher
  26. Yang Y, Groshong J, Matta H, Gopalakrishnan R, Yi H, Chaudhary P. Constitutive NF-kappaB activation confers interleukin 6 (IL6) independence and resistance to dexamethasone and Janus kinase inhibitor INCB018424 in murine plasmacytoma cells. J Biol Chem. 2011;286:27988-97 pubmed publisher
    ..virus 1-encoded Tax protein, which resembles K13 in inducing constitutive NF-?B activation, similarly protected plasmacytoma cells against IL6 withdrawal-induced apoptosis...
  27. Bachar G, Goldstein D, Brown D, Tsang R, Lockwood G, Perez Ordonez B, et al. Solitary extramedullary plasmacytoma of the head and neck--long-term outcome analysis of 68 cases. Head Neck. 2008;30:1012-9 pubmed publisher
    ..Head and neck solitary extramedullary plasmacytomas are rare plasma cell neoplasms. Literature review reveals only small numbers of reports. The objective was to review our experience with treating patients with this neoplasm...
  28. Kumar S. Solitary plasmacytoma: is radiation therapy sufficient?. Am J Hematol. 2008;83:695-6 pubmed publisher
  29. Sia D, Cannon P, Selva D. Extramedullary plasmacytoma arising from the lacrimal gland. Clin Exp Ophthalmol. 2010;38:895-8 pubmed publisher
    ..The lesion was excised and histology confirmed an orbital plasmacytoma. Multiple myeloma screening was negative and a solitary extramedullary plasmacytoma arising from the lacrimal ..
  30. D Costa K, Emslie D, Metcalf D, Smyth G, Karnowski A, Kallies A, et al. Blimp1 is limiting for transformation in a mouse plasmacytoma model. Blood. 2009;113:5911-9 pubmed publisher
    ..Thus, the role of PRDM1/BLIMP1 in transformation of mature B cells is unclear. We have used a plasmacytoma-prone transgenic mouse model to study the effect of Blimp1 loss on plasmacytoma prevalence, latency, and ..
  31. Qi C, Shin D, Li Z, Wang H, Feng J, Hartley J, et al. Anaplastic plasmacytomas: relationships to normal memory B cells and plasma cell neoplasms of immunodeficient and autoimmune mice. J Pathol. 2010;221:106-16 pubmed publisher
    ..Published in 2010 by John Wiley & Sons, Ltd. ..
  32. Chua S, O Connor S, Wong W, Ganatra R. Case report: Solitary plasmacytoma of bone with oncogenic osteomalacia: recurrence of tumour confirmed by PET/CT. A case report with a review of the radiological literature. Br J Radiol. 2008;81:e110-4 pubmed publisher
    We describe a case of oncogenic osteomalacia secondary to solitary plasmacytoma of the vertebral body of T3. The patient presented with symptoms of hypophosphataemia...
  33. Agool A, Slart R, Dierckx R, Kluin P, Visser L, Jager P, et al. Somatostatin receptor scintigraphy might be useful for detecting skeleton abnormalities in patients with multiple myeloma and plasmacytoma. Eur J Nucl Med Mol Imaging. 2010;37:124-30 pubmed publisher
    ..Somatostatin receptor expression has been demonstrated on a number of plasma cell lines. Therefore, we questioned whether somatostatin receptor scintigraphy (SRS) can be used to demonstrate in vivo multiple myeloma (MM) activity...
  34. Bal A, Kumar Y, Das A, Bhatia A. Signet ring cell plasmacytoma: a rare morphological variant. Pathology. 2008;40:545-6 pubmed publisher
  35. Avila A, Villalpando A, Montoya G, Luna M. Clinical features and differential diagnoses of solitary extramedullary plasmacytoma of the thyroid: a case report. Ann Diagn Pathol. 2009;13:119-23 pubmed publisher
    ..The tumor fulfilled the criteria of primary solitary extramedullary plasmacytoma (SEP), including cellular expression of the CD138 and lambda light chain antibodies...
  36. Terada T. Solitary plasmacytoma of the thoracic vertebra presenting with sudden paraplegia and back pain: a pathologic case report. Pathol Oncol Res. 2011;17:167-9 pubmed publisher
    Solitary plasmacytoma (SPC) accounts for 5% of plasma cell neoplasm. SPC of the spine is relatively rare, and SPC presenting with sudden paraplegia is very rare...
  37. Wei J, Tong H, Zhu W, Liu H, Zhang F, Yu W, et al. Bortezomib in treatment of extramedullary plasmacytoma of the pancreas. Hepatobiliary Pancreat Dis Int. 2009;8:329-31 pubmed
    Extramedullary pancreatic plasmacytoma treated with bortezomib is rarely reported.
  38. Zhang K, Kagan D, DuBois W, Robinson R, Bliskovsky V, Vass W, et al. Mndal, a new interferon-inducible family member, is highly polymorphic, suppresses cell growth, and may modify plasmacytoma susceptibility. Blood. 2009;114:2952-60 pubmed publisher
    ..Mndal is highly polymorphic among inbred mouse strains, because it is absent in 10 of 24 strains. This polymorphism may have implications for other disease modifiers mapping to the same region...
  39. Soutar R, Lucraft H, Jackson G, Reece A, Bird J, Low E, et al. Guidelines on the diagnosis and management of solitary plasmacytoma of bone and solitary extramedullary plasmacytoma. Br J Haematol. 2004;124:717-26 pubmed
  40. Tsang R, Gospodarowicz M, Pintilie M, Bezjak A, Wells W, Hodgson D, et al. Solitary plasmacytoma treated with radiotherapy: impact of tumor size on outcome. Int J Radiat Oncol Biol Phys. 2001;50:113-20 pubmed
    Solitary plasmacytoma (SP) is a rare presentation of plasma cell neoplasms...
  41. Lamy O, von Bremen K, Burckhardt P. Breast plasmacytoma. Leuk Lymphoma. 2000;37:611-5 pubmed
    An unusual case of breast plasmacytoma associated with a multiple myeloma is reported. Breast plasmacytoma is exceedingly rare...
  42. Pattengale P. Role of interleukin-6 in the pathogenesis of murine plasmacytoma and human multiple myeloma. Am J Pathol. 1997;151:647-9 pubmed
  43. Cozen W, Gebregziabher M, Conti D, Van Den Berg D, Coetzee G, Wang S, et al. Interleukin-6-related genotypes, body mass index, and risk of multiple myeloma and plasmacytoma. Cancer Epidemiol Biomarkers Prev. 2006;15:2285-91 pubmed
    ..We evaluated IL-6 genotypes and body mass index (BMI) in a case-control study of multiple myeloma and plasmacytoma. DNA samples and questionnaires were obtained from incident cases of multiple myeloma (n = 134) and ..
  44. Holland J, Trenkner D, Wasserman T, Fineberg B. Plasmacytoma. Treatment results and conversion to myeloma. Cancer. 1992;69:1513-7 pubmed
    Forty-six cases of solitary plasmacytoma were reviewed for response to radiation and progression to multiple myeloma. Cases were classified as solitary plasmacytomas of bone (SPB) (32 cases) or extramedullary plasmacytomas (EP) (14 cases)...
  45. Bernard O, Gough N, Adams J. Plasmacytomas with more than one immunoglobulin kappa mRNA: implications for allelic exclusion. Proc Natl Acad Sci U S A. 1981;78:5812-6 pubmed
    ..These observations are compatible with a stochastic model for allelic exclusion in which productive and nonproductive V--J recombination events occur at a certain frequency for each allele. ..
  46. Kadokura M, Tanio N, Nonaka M, Yamamoto S, Kataoka D, Kushima M, et al. A surgical case of solitary plasmacytoma of rib origin with biclonal gammopathy. Jpn J Clin Oncol. 2000;30:191-5 pubmed
    Localized solitary plasmacytoma of the bone (SPB) is a rare disease and is characterized by only one or two isolated bone lesions with no evidence of disease dissemination...
  47. Wang Y, Sugiyama H, Axelson H, Panda C, Babonits M, Ma A, et al. Functional homology between N-myc and c-myc in murine plasmacytomagenesis: plasmacytoma development in N-myc transgenic mice. Oncogene. 1992;7:1241-7 pubmed
    ..All plasmacytomas expressed the N-myc transgene, while none of them expressed either c-myc or endogenous N-myc. None of the tumors carried the usual plasmacytoma-associated translocations.
  48. Kovalchuk A, Kim J, Park S, Coleman A, Ward J, Morse H, et al. IL-6 transgenic mouse model for extraosseous plasmacytoma. Proc Natl Acad Sci U S A. 2002;99:1509-14 pubmed
    ..comprise plasma cell myeloma, otherwise known as multiple myeloma, Ig deposition and heavy chain diseases, and plasmacytoma (PCT)...
  49. Petrucci M, Tirindelli M, De Muro M, Martini V, Levi A, Mandelli F. Extramedullary liver plasmacytoma a rare presentation. Leuk Lymphoma. 2003;44:1075-6 pubmed
    Liver plasmacytoma is a very rare form of solitary plasmacytoma, in fact the presence of plasma cells in the liver is generally associated with a more aggressive form of multiple myeloma...
  50. Avet Loiseau H, Gerson F, Magrangeas F, Minvielle S, Harousseau J, Bataille R. Rearrangements of the c-myc oncogene are present in 15% of primary human multiple myeloma tumors. Blood. 2001;98:3082-6 pubmed
  51. Guilloux Y, Bai X, Liu X, Zheng P, Liu Y. Optimal induction of effector but not memory antitumor cytotoxic T lymphocytes involves direct antigen presentation by the tumor cells. Cancer Res. 2001;61:1107-12 pubmed
    ..Our results demonstrate that optimal induction of effector CTLs, but not memory CTLs, requires direct antigen presentation by the tumor cells...
  52. Susnerwala S, Shanks J, Banerjee S, Scarffe J, Farrington W, Slevin N. Extramedullary plasmacytoma of the head and neck region: clinicopathological correlation in 25 cases. Br J Cancer. 1997;75:921-7 pubmed
    ..0019) but not for overall survival (P= 0.12). The median survival and 5-year overall survival is 68 months and 58.9% respectively. We recommend consideration of adjuvant chemotherapy in patients with higher grade disease...
  53. Mai S, Wiener F. The impact of p53 loss on murine plasmacytoma development. Chromosome Res. 2002;10:239-51 pubmed
    ..The 42.2% incidence in N3p53-/- mice is similar to the percentages recorded in groups of conventional BALB/cAn mice. The possible mechanisms underlying the accelerated tumorigenesis and the shift in translocation patterns are discussed...
  54. Fujikata S, Tanji N, Aoki K, Ohoka H, Hojo N, Yokoyama M. Extramedullary plasmacytoma arising from an adrenal gland. Urology. 2002;60:514 pubmed
    Extramedullary plasmacytoma is a rare malignant neoplasm typically arising outside the bone marrow of patients who show no clinical evidence of multiple myeloma...
  55. Cangiarella J, Waisman J, Cohen J, Chhieng D, Symmans W, Goldenberg A. Plasmacytoma of the breast. A report of two cases diagnosed by aspiration biopsy. Acta Cytol. 2000;44:91-4 pubmed
    Extramedullary plasmacytoma of the breast is an uncommon neoplasm, occurring either as a solitary tumor or as evidence of disseminated multiple myeloma.
  56. Gado K, Silva S, Paloczi K, Domjan G, Falus A. Mouse plasmacytoma: an experimental model of human multiple myeloma. Haematologica. 2001;86:227-36 pubmed
    ..There is no ideal animal model for human multiple myeloma (MM). All the models resemble the human disease in some respect, but none of them fulfils all the criteria of a perfect animal model...
  57. Axelson H, Wang Y, Silva S, Mattei M, Klein G. Juxtaposition of N-myc and Ig kappa through a reciprocal t(6;12) translocation in a mouse plasmacytoma. Genes Chromosomes Cancer. 1994;11:85-90 pubmed
    ..Its tumorigenic influence would become manifest only at the time when the cell would normally be programmed to leave the cycling compartment, in connection with its terminal differentiation...
  58. Yavas O, Altundag K, Sungur A. Extramedullary plasmacytoma of nasopharynx and larynx: synchronous presentation. Am J Hematol. 2004;75:264-5 pubmed
  59. Park S, Shaffer A, Kim J, DuBois W, Potter M, Staudt L, et al. Insertion of Myc into Igh accelerates peritoneal plasmacytomas in mice. Cancer Res. 2005;65:7644-52 pubmed
    ..These findings indicated that the iMyc(Emu) transgene accelerates plasmacytoma development by collaborating with tumor susceptibility alleles of strain C and circumventing the requirement ..
  60. Ganesh M, Sankar N, Jagannathan R. Extramedullary plasmacytoma presenting as upper back pain. J R Soc Promot Health. 2000;120:262-5 pubmed
    Extramedullary plasmacytoma (EMP) is a rare soft tissue plasma cell tumour, usually presenting as a mass within the upper respiratory tract. It is most unusual for it to present in the posterior mediastinum as a primary solitary lesion...
  61. Avcu F, Ural A, Yilmaz M, Ozcan A, Ide T, Kurt B, et al. The bisphosphonate zoledronic acid inhibits the development of plasmacytoma induced in BALB/c mice by intraperitoneal injection of pristane. Eur J Haematol. 2005;74:496-500 pubmed
    ..We have investigated the effect of the potent bisphosphonate, zoledronic acid (ZOL), on the development of pristane (2,6,10,14-tetramethylpentadecane)-induced plasmacytoma (PCT) in six-week-old BALB/c mice.
  62. Jyothirmayi R, Gangadharan V, Nair M, Rajan B. Radiotherapy in the treatment of solitary plasmacytoma. Br J Radiol. 1997;70:511-6 pubmed
    Solitary plasmacytoma of bone (SPB) and extramedullary plasmacytoma (EMP) are rare. High local control rates are reported with radiotherapy, although the optimal dose and extent of radiotherapy portals remains controversial...
  63. Durie B, Waxman A, D Agnolo A, Williams C. Whole-body (18)F-FDG PET identifies high-risk myeloma. J Nucl Med. 2002;43:1457-63 pubmed
    ..The purpose of this study was to evaluate the clinical utility of whole-body PET with (18)F-FDG in patients with multiple myeloma and related monoclonal diseases...
  64. Niitsu N, Kohri M, Hayama M, Nakamine H, Nakamura N, Bessho M, et al. Primary pulmonary plasmacytoma involving bilateral lungs and marked hypergammaglobulinemia: differentiation from extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue. Leuk Res. 2005;29:1361-4 pubmed
    ..in addition to the absence of reactive lymph follicles and fibrosis, the patient was diagnosed as having plasmacytoma. There was no proliferation of plasma cells in the bone marrow...
  65. Nakashima T, Matsuda K, Haruta A. Extramedullary plasmacytoma of the larynx. Auris Nasus Larynx. 2006;33:219-22 pubmed
    Extramedullary plasmacytoma (EMP) is a rare plasma cell neoplasm that occurs in the soft tissues, especially in the upper airways...