pancytopenia

Summary

Summary: Deficiency of all three cell elements of the blood, erythrocytes, leukocytes and platelets.

Top Publications

  1. Tsangaris E, Adams S, Yoon G, Chitayat D, Lansdorp P, Dokal I, et al. Ataxia and pancytopenia caused by a mutation in TINF2. Hum Genet. 2008;124:507-13 pubmed publisher
    The syndrome of ataxia-pancytopenia is an autosomal dominant disorder characterized by cerebellar ataxia, peripheral neuropathies, pancytopenia and a predilection to myelodysplastic syndrome and acute myeloid leukemia...
  2. Assad A, Amann B, Friedrich A, Deeg C. Immunophenotyping and characterization of BNP colostra revealed pathogenic alloantibodies of IgG1 subclass with specifity to platelets, granulocytes and monocytes of all maturation stages. Vet Immunol Immunopathol. 2012;147:25-34 pubmed publisher
    Bovine neonatal pancytopenia (BNP) is mainly characterized by multiple haemorrhages, thrombocytopenia and leukocytopenia as a result of bone marrow depletion...
  3. Foucras G, Corbière F, Tasca C, Pichereaux C, Caubet C, Trumel C, et al. Alloantibodies against MHC class I: a novel mechanism of neonatal pancytopenia linked to vaccination. J Immunol. 2011;187:6564-70 pubmed publisher
    ..Since 2007, a hemorrhagic syndrome due to thrombocytopenia and designated as bovine neonatal pancytopenia (BNP) has been recognized in calves in several European countries...
  4. Pardon B, Steukers L, Dierick J, Ducatelle R, Saey V, Maes S, et al. Haemorrhagic diathesis in neonatal calves: an emerging syndrome in Europe. Transbound Emerg Dis. 2010;57:135-46 pubmed publisher
    ..Early in the disease, the mental state of the animals is uncompromised. The typical haematological finding is pancytopenia, with severe to complete thrombocytopenia being the cause of the increased susceptibility to bleeding...
  5. Gosselin V, Fecteau G, Nichols S. Presumptive bovine neonatal pancytopenia in a Holstein calf in Québec. Can Vet J. 2011;52:788-90 pubmed
    ..The animal was negative by PCR for bovine virus diarrhea virus antigen. The findings supported a diagnosis of bovine neonatal pancytopenia. Treatments included fresh whole blood transfusion and antibiotics. The animal recovered fully.
  6. Witt K, Weber C, Meyer J, Buchheit Renko S, Muller K. Haematological analysis of calves with bovine neonatal pancytopenia. Vet Rec. 2011;169:228 pubmed publisher
    ..from 61 neonatal Holstein calves originating from a farm in Germany with a high incidence of bovine neonatal pancytopenia (BNP)...
  7. Pandey R, Garg R, Darlong V, Punj J, Kumar A. Role of splenic artery partial embolization in a patient with portal hypertension and pancytopenia undergoing hysterectomy under anesthesia. AANA J. 2012;80:96-8 pubmed
    ..A 32-year-old woman was scheduled for total abdominal hysterectomy for multiple fibroids and menorrhagia with pancytopenia. She also had diagnoses of chronic liver disease with cirrhotic changes, portal hypertension, and grade IV ..
  8. Thapa R, Ranjan R, Patra V, Chakrabartty S. Childhood cerebral vivax malaria with pancytopenia. J Pediatr Hematol Oncol. 2009;31:116-7 pubmed publisher
    We report on a 7-year-old girl with cerebral vivax malaria complicated by pancytopenia. The diagnosis of malaria was done by demonstration of trophozoites of Plasmodium vivax in the peripheral blood smear and confirmed by both a species-..
  9. Krappmann K, Weikard R, Gerst S, Wolf C, Kuhn C. A genetic predisposition for bovine neonatal pancytopenia is not due to mutations in coagulation factor XI. Vet J. 2011;190:225-9 pubmed publisher
    Bovine neonatal pancytopenia (BNP) is a newly emerging disease in many European countries that causes haemorrhagic diathesis and mortality in neonatal calves...

More Information

Publications62

  1. Thorogood N, Atwal S, Mills W, Jenner M, Lewis D, Cavenagh J, et al. The risk of antimalarials in patients with renal failure. Postgrad Med J. 2007;83:e8 pubmed
    ..at full dose leading to life threatening toxicity with severe acute megaloblastic anaemia, symptomatic pancytopenia and exfoliative dermatitis...
  2. Akoum R, Michel S, Wafic T, Emile B, Marwan M, Khaled H, et al. Myelodysplastic syndrome and pancytopenia responding to treatment of hyperthyroidism: peripheral blood and bone marrow analysis before and after antihormonal treatment. J Cancer Res Ther. 2007;3:43-6 pubmed
    Hematological disorders, especially single lineage abnormalities, have been described in hyperthyroidism. Pancytopenia has been reported, without myelodysplastic syndrome or megaloblastic anemia...
  3. Watanabe N, Narimatsu H, Noh J, Yamaguchi T, Kobayashi K, Kami M, et al. Antithyroid drug-induced hematopoietic damage: a retrospective cohort study of agranulocytosis and pancytopenia involving 50,385 patients with Graves' disease. J Clin Endocrinol Metab. 2012;97:E49-53 pubmed publisher
    ..Incidence and clinical features of ATD-induced agranulocytosis and pancytopenia were evaluated...
  4. Jones B, Sauter Louis C, Henning J, Stoll A, Nielen M, van Schaik G, et al. Calf-level factors associated with bovine neonatal pancytopenia--a multi-country case-control study. PLoS ONE. 2013;8:e80619 pubmed publisher
    Bovine neonatal pancytopenia (BNP), a high fatality condition causing haemorrhages in calves aged less than 4 weeks, was first reported in 2007 in Germany and subsequently observed at low incidence in other European countries and New ..
  5. Ballingall K, Nath M, Holliman A, Laming E, Steele P, Willoughby K. Lack of evidence for an association between MHC diversity and the development of bovine neonatal pancytopenia in Holstein dairy cattle. Vet Immunol Immunopathol. 2011;141:128-32 pubmed publisher
    Bovine neonatal pancytopenia (BNP), a disease of neonatal calves, has been described in a number of European countries since 2006...
  6. Cordiano V, Miserocchi F, Storti M. Bone marrow metastases from anaplastic oligodendroglioma presenting with pancytopenia and hypogammaglobulinemia: a case report. Tumori. 2011;97:808-11 pubmed publisher
    ..of visceral metastases was obtained by bone marrow biopsy, the patient developed diffuse bone pain, pancytopenia, hypercalcemia, and panhypogammaglobulinemia...
  7. Laming E, Melzi E, Scholes S, Connelly M, Bell C, Ballingall K, et al. Demonstration of early functional compromise of bone marrow derived hematopoietic progenitor cells during bovine neonatal pancytopenia through in vitro culture of bone marrow biopsies. BMC Res Notes. 2012;5:599 pubmed publisher
    Bovine neonatal pancytopenia (BNP) is a syndrome characterised by thrombocytopenia associated with marked bone marrow destruction in calves, widely reported since 2007 in several European countries and since 2011 in New Zealand...
  8. Euler K, Hauck S, Ueffing M, Deeg C. Bovine neonatal pancytopenia--comparative proteomic characterization of two BVD vaccines and the producer cell surface proteome (MDBK). BMC Vet Res. 2013;9:18 pubmed publisher
    Bovine neonatal pancytopenia (BNP) is a disease syndrome in newborn calves of up to four weeks of age, first observed in southern Germany in 2006. By now, cases have been reported in several countries around the globe...
  9. Friedrich A, Büttner M, Rademacher G, Klee W, Weber B, Muller M, et al. Ingestion of colostrum from specific cows induces Bovine Neonatal Pancytopenia (BNP) in some calves. BMC Vet Res. 2011;7:10 pubmed publisher
    ..The syndrome, now uniformly called Bovine Neonatal Pancytopenia (BNP), is characterized by multiple (external and internal) haemorrhages, thrombocytopenia, leukocytopenia, and ..
  10. Bridger P, Bauerfeind R, Wenzel L, Bauer N, Menge C, Thiel H, et al. Detection of colostrum-derived alloantibodies in calves with bovine neonatal pancytopenia. Vet Immunol Immunopathol. 2011;141:1-10 pubmed publisher
    Bovine neonatal pancytopenia (BNP) is an emerging calf disease of unknown cause characterized by a pronounced susceptibility to bleeding as a result of a pancytopenia and bone marrow depletion...
  11. Lambton S, Colloff A, Smith R, Caldow G, Scholes S, Willoughby K, et al. Factors associated with bovine neonatal pancytopenia (BNP) in calves: a case-control study. PLoS ONE. 2012;7:e34183 pubmed publisher
    Bovine neonatal pancytopenia (BNP; previously known as idiopathic haemorrhagic diathesis and commonly known as bleeding calf syndrome) is a novel haemorrhagic disease of young calves which has emerged in a number of European countries ..
  12. Gursel O, Altun D, Atay A, Bedir O, Kurekci A. Mycoplasma pneumoniae infection associated with pancytopenia: a case report. J Pediatr Hematol Oncol. 2009;31:760-2 pubmed publisher
    ..pneumoniae associated pneumonia. It is suggested that even though very rare, M. pneumoniae infection should be considered as the underlying disease in a patient presenting with pancytopenia.
  13. Sari I, Altuntas F, Hacioglu S, Kocyigit I, Sevinc A, Sacar S, et al. A multicenter retrospective study defining the clinical and hematological manifestations of brucellosis and pancytopenia in a large series: Hematological malignancies, the unusual cause of pancytopenia in patients with brucellosis. Am J Hematol. 2008;83:334-9 pubmed
    The aim of the study is to review the clinical manifestations and the hematological findings of brucellosis and pancytopenia, with or without hematological malignancies...
  14. Shimada A, Onozato T, Hoshi E, Togashi Y, Matsui M, Miyake Y, et al. Pancytopenia with bleeding tendency associated with bone marrow aplasia in a Holstein calf. J Vet Med Sci. 2007;69:1317-9 pubmed
    ..Severe pancytopenia was observed in the blood examination...
  15. Bautista Quach M, Liao Y, Hsueh C. Pancytopenia associated with clonazepam. J Hematol Oncol. 2010;3:24 pubmed publisher
    ..To our knowledge, this is the first reported case of pancytopenia associated with clonazepam...
  16. Deutskens F, Lamp B, Riedel C, Wentz E, Lochnit G, Doll K, et al. Vaccine-induced antibodies linked to bovine neonatal pancytopenia (BNP) recognize cattle major histocompatibility complex class I (MHC I). Vet Res. 2011;42:97 pubmed publisher
    A mysterious disease affecting calves, named bovine neonatal pancytopenia (BNP), emerged in 2007 in several European countries...
  17. Klimaszyk D, Łukasik Głebocka M. [Pancytopenia in the course of acute valproic acid poisoning--case report]. Przegl Lek. 2011;68:539-42 pubmed
    ..Less common toxicities include neutropenia and anemia. 58 years old female with pancytopenia in the course of acute valproic acid intoxication was described...
  18. Kappe E, Halami M, Schade B, Alex M, Hoffmann D, Gangl A, et al. Bone marrow depletion with haemorrhagic diathesis in calves in Germany: characterization of the disease and preliminary investigations on its aetiology. Berl Munch Tierarztl Wochenschr. 2010;123:31-41 pubmed
    ..Blood analysis of five animals indicated an aplastic pancytopenia. The resulting thrombocytopenia is regarded as major pathomechanism of this Haemorrhagic Disease Syndrome (HDS)...
  19. Jha A, Sayami G, Adhikari R, Panta A, Jha R. Bone marrow examination in cases of pancytopenia. JNMA J Nepal Med Assoc. 2008;47:12-7 pubmed
    This study was carried to identify the causes of pancytopenia and to find out the bone marrow morphology in cases of pancytopenia...
  20. Bastian M, Holsteg M, Hanke Robinson H, Duchow K, Cussler K. Bovine Neonatal Pancytopenia: is this alloimmune syndrome caused by vaccine-induced alloreactive antibodies?. Vaccine. 2011;29:5267-75 pubmed publisher
    Bovine Neonatal Pancytopenia (BNP) is a new emerging disease observed since 2007 in Germany and neighbouring countries. The syndrome affects newborn calves and is characterized by pancytopenia, severe bleeding and high lethality...
  21. Kasonta R, Sauter Louis C, Holsteg M, Duchow K, Cussler K, Bastian M. Effect of the vaccination scheme on PregSure® BVD induced alloreactivity and the incidence of Bovine Neonatal Pancytopenia. Vaccine. 2012;30:6649-55 pubmed publisher
    Bovine Neonatal Pancytopenia (BNP) is a new neonate-maternal incompatibility phenomenon caused by vaccine-induced, maternal alloantibodies...
  22. Fu R, Chen J, Wang H, Wang J, Li L, Liu H, et al. [Quantity and function of regulatory T cells in hemocytopenic patients with positive BMMNC-Coombs test]. Zhonghua Yi Xue Za Zhi. 2010;90:2989-93 pubmed
    To investigate the quantity and function of regulatory T cells in immune related pancytopenia (IRP) and explore the significance of Treg cells in the pathogenesis of IRP. Sixty-six IRP patients and 24 healthy donors were enrolled...
  23. Chen J, Fu R, Li L, Liu H, Wang Y, Wang H, et al. [Variation in complement level and its significance in cytopenia patients with positive BMMNC-Coombs]. Zhonghua Xue Ye Xue Za Zhi. 2009;30:454-7 pubmed
    ..230, P=0.032) of CBCPC patients were positively correlated with their CH50 level. The hematocytopenia of CBCPC patients might be related to the hematopoietic cells destruction caused by auto-antibody activated complements. ..
  24. Mawad R, Hsieh A, Damon L. Graft-versus-host disease presenting with pancytopenia after en bloc multiorgan transplantation: case report and literature review. Transplant Proc. 2009;41:4431-3 pubmed publisher
    ..She developed isolated pancytopenia approximately 4 months after receiving an en bloc transplant involving the liver, kidney, small bowel, and ..
  25. Rahman I, Narasimhan K, Aziz S, Owens W. Gasoline ingestion: a rare cause of pancytopenia. Am J Med Sci. 2009;338:433-4 pubmed publisher
    ..We are reporting a rare case of pancytopenia along with aspiration pneumonia and multisystem organ failure in a 58-year-old male after prolonged intentional ..
  26. Halfdanarson T, Walker J, Litzow M, Hanson C. Severe vitamin B12 deficiency resulting in pancytopenia, splenomegaly and leukoerythroblastosis. Eur J Haematol. 2008;80:448-51 pubmed publisher
    Deficiency of vitamin B12 is a well known cause of megaloblastic anemia and pancytopenia. Splenomegaly and leukoerythroblastosis are much less well known manifestations of B12 deficiency...
  27. Wang Y, Fu R, Shao Z, Wang H, Xing L, Liu H, et al. [Study on quantity and function of bone marrow macrophages in patients with BMMNC-Coombs Test(+) pancytopenia]. Zhonghua Xue Ye Xue Za Zhi. 2009;30:538-42 pubmed
    To explore the quantity and function of bone marrow (BM) macrophages in patients with BMMNC-Coombs Test(+) pancytopenia (BCTP)...
  28. Pardon B, Stuyven E, Stuyvaert S, Hostens M, Dewulf J, Goddeeris B, et al. Sera from dams of calves with bovine neonatal pancytopenia contain alloimmune antibodies directed against calf leukocytes. Vet Immunol Immunopathol. 2011;141:293-300 pubmed publisher
    Bovine neonatal pancytopenia (BNP) is a bleeding and pancytopenic syndrome in neonatal calves, which recently emerged all over Europe...
  29. Bell C, Rocchi M, Dagleish M, Melzi E, Ballingall K, Connelly M, et al. Reproduction of bovine neonatal pancytopenia (BNP) by feeding pooled colostrum reveals variable alloantibody damage to different haematopoietic lineages. Vet Immunol Immunopathol. 2013;151:303-14 pubmed publisher
    Bovine neonatal pancytopenia (BNP) is a recently described haemorrhagic disease of calves characterised by thrombocytopenia, leucopenia and bone marrow depletion...
  30. Black L, Soltau T, Kelly D, Berkow R. Shwachman-Diamond syndrome presenting in a premature infant as pancytopenia. Pediatr Blood Cancer. 2008;51:123-4 pubmed publisher
    ..We report a premature infant born at 33 weeks gestation who was small for gestational age and displayed persistent cytopenias requiring transfusion. Genetic testing confirmed a diagnosis of Shwachman-Diamond syndrome (SDS). ..
  31. Hegazi M, Kumar R, Bitar Z, Ibrahim E. Pancytopenia related to Graves' disease. Ann Saudi Med. 2008;28:48-9 pubmed
  32. Kobashi Y, Fukuda M, Yoshida K, Oka M. An indeterminate QuantiFERON TB-2G response for miliary tuberculosis, due to severe pancytopenia. J Infect Chemother. 2007;13:414-7 pubmed
    ..response to the QuantiFERON (QFT) TB-2G (Cellestis; South Melbourne, Australia) test was indeterminate due to pancytopenia (lymphocytopenia)...
  33. Schröter P, Kuiper H, Holsteg M, Puff C, Haas L, Baumgartner W, et al. [Reproducibility of bovine neonatal pancytopenia (BNP) via the application of colostrum]. Berl Munch Tierarztl Wochenschr. 2011;124:390-400 pubmed
    A haemorrhagic diathesis has been observed in young calves since 2007 which is described as bovine neonatal pancytopenia (BNP) and presents a completely new disease...
  34. Fukunaka M, Toyoda Y, Kobayashi Y, Furuoka H, Inokuma H. Bone marrow aplasia with pancytopenia and hemorrhage in a Japanese Black calf. J Vet Med Sci. 2010;72:1655-6 pubmed
    ..Necropsy findings revealed subcutaneous petechial hemorrhage and severe bone marrow aplasia. This is the first confirmed case of pancytopenia and hemorrhage associated with bone marrow aplasia in a Japanese Black calf.
  35. Laway B, Bhat J, Mir S, Khan R, Lone M, Zargar A. Sheehan's syndrome with pancytopenia--complete recovery after hormone replacement (case series with review). Ann Hematol. 2010;89:305-8 pubmed publisher
    Reports of pancytopenia in patients with Sheehan's syndrome are rare, because the disorder is not commonly seen in western countries. A case series of pancytopenia in three patients of Sheehan's syndrome is presented...
  36. Sauter Louis C, Carlin A, Friedrich A, Assad A, Reichmann F, Rademacher G, et al. Case control study to investigate risk factors for bovine neonatal pancytopenia (BNP) in young calves in southern Germany. Prev Vet Med. 2012;105:49-58 pubmed publisher
    ..factors associated with the observed increase in numbers of calves showing clinical signs of Bovine Neonatal Pancytopenia (BNP) since 2006 in southern Germany. Interviews were conducted between August 2008 and June 2010...
  37. Luppi M, Barozzi P, Rasini V, Riva G, Re A, Rossi G, et al. Severe pancytopenia and hemophagocytosis after HHV-8 primary infection in a renal transplant patient successfully treated with foscarnet. Transplantation. 2002;74:131-2 pubmed
    ..Severe peripheral cytopenia may be a posttransplant complication after HHV-8 infection, for which treatment with foscarnet seems appropriate...
  38. Yokota K, Hirano M, Akiba H, Adachi D, Takeishi M, Akiyama Y, et al. [A case of Behçet's disease with esophageal ulcers complicated with systemic sclerosis, chronic hepatitis C, and pancytopenia]. Nihon Rinsho Meneki Gakkai Kaishi. 2004;27:164-70 pubmed
    ..Asymptomatic mild pancytopenia was also found...
  39. Deng J, Tovar J. Pancytopenia with levofloxacin therapy for pelvic inflammatory disease in an otherwise healthy young patient. Ann Pharmacother. 2006;40:1692-3 pubmed
  40. Aalfs C, van den Berg H, Barth P, Hennekam R. The Hoyeraal-Hreidarsson syndrome: the fourth case of a separate entity with prenatal growth retardation, progressive pancytopenia and cerebellar hypoplasia. Eur J Pediatr. 1995;154:304-8 pubmed
    We report on a boy with prenatal growth retardation, progressive pancytopenia, cerebellar hypoplasia, microcephaly and developmental delay...
  41. Bilello S, Bao F, Veillon D, Muldoon R, Cotelingam J. Pathology case of the month. Elderly man with pancytopenia. Bone marrow granulomas secondary to amiodarone. J La State Med Soc. 2006;158:10-2 pubmed
  42. Khunger J, Arulselvi S, Sharma U, Ranga S, Talib V. Pancytopenia--a clinico haematological study of 200 cases. Indian J Pathol Microbiol. 2002;45:375-9 pubmed
    The present study was designed to ascertain the percentage of occurrence and causes of pancytopenia. All the cases of pancytopenia from July 2001 to June 2002 (one year) were examined in the Department of haematology, Safdarjung Hospital, ..
  43. Kim D, Kim J, Park Y, Jung K, Chung H, Shin S, et al. Case of complete recovery of pancytopenia after treatment of hypopituitarism. Ann Hematol. 2004;83:309-12 pubmed
    We describe a 55-year-old woman who presented with pancytopenia with a normocytic and normochromic anemia which was progressive despite conventional treatments such as folic acid, vitamin B6, and oxymetholone...
  44. McEwen J, Purcell P, Hill R, Calcino L, Riley C. The incidence of pancytopenia in patients taking leflunomide alone or with methotrexate. Pharmacoepidemiol Drug Saf. 2007;16:65-73 pubmed
    To estimate the incidence of pancytopenia in patients taking leflunomide with or without methotrexate in Australia...
  45. Niitsu N, Kohri M, Togano T, Nakamine H, Nakamura S, Iwabuchi K, et al. Development of hepatosplenic gammadelta T-cell lymphoma with pancytopenia during early pregnancy: a case report and review of the literature. Eur J Haematol. 2004;73:367-71 pubmed
    ..The patient was a 31-yr-old female who was referred to our hospital because of pancytopenia and splenomegaly at the time of the14th week of her gestation...
  46. Sun C, Lin H, Chen Y, Tsai C, Wu M. Leukemoid reaction after methotrexate-induced pancytopenia in a patient undergoing continuous ambulatory peritoneal dialysis. Chang Gung Med J. 2006;29:513-7 pubmed
    ..woman with systemic lupus erythematosus undergoing chronic peritoneal dialysis developed severe mucositis and pancytopenia after low-dose methotrexate treatment for arthritis...
  47. Zheng L, Dai H, Qiu J, Huang Q, Shen B. Disruption of the FEN-1/PCNA interaction results in DNA replication defects, pulmonary hypoplasia, pancytopenia, and newborn lethality in mice. Mol Cell Biol. 2007;27:3176-86 pubmed
    ..All newborn FFAA mutant pups died at birth, likely due to pulmonary hypoplasia and pancytopenia. Collectively, our data demonstrate the importance of the FEN-1/PCNA complex in DNA replication and in the ..
  48. Arunkumar P, Crook T, Ballard J. Disseminated histoplasmosis presenting as pancytopenia in a methotrexate-treated patient. Am J Hematol. 2004;77:86-7 pubmed
  49. Trizzino A, Farruggia P, Russo D, D Angelo P, Tropia S, Benigno V, et al. Congenital hepatic fibrosis: a very uncommon cause of pancytopenia in children. J Pediatr Hematol Oncol. 2005;27:567-8 pubmed
    ..The authors report an unusual case of ARPKD presenting with hepatosplenomegaly and cytopenia mimicking acute leukemia...
  50. Heegaard E, Madsen H, Schmiegelow K. Transient pancytopenia preceding acute lymphoblastic leukaemia (pre-ALL) precipitated by parvovirus B19. Br J Haematol. 2001;114:810-3 pubmed
    A preleukaemic phase, typified by pancytopenia and bone marrow (BM) hypoplasia, is an uncommon but well-documented prelude to acute lymphoblastic leukaemia (pre-ALL) in children...
  51. Takagi M, Unno A, Maruyama T, Kaneko K, Obinata K. Human herpesvirus-6 (HHV-6)-associated hemophagocytic syndrome. Pediatr Hematol Oncol. 1996;13:451-6 pubmed
    ..In this study, we describe a 23-month-old girl who exhibited typical manifestations of VAHS associated with HHV-6 infection. To the best of our knowledge, this case is the fifth reported case in the English literature. ..
  52. Cokca F, Yilmaz Bozkurt G, Azap A, Memikoglu O, Tekeli E. Meningoencephalitis, pancytopenia, pulmonary insufficiency and splenic abscess in a patient with brucellosis. Saudi Med J. 2006;27:539-41 pubmed
    ..In this article, we report a case of disseminated brucellosis who was initially diagnosed as myelodysplastic syndrome MDS and meningoencephalitis, pulmonary symptoms, and splenic abscess formation occurred thereafter. ..
  53. Fu R, Shao Z, He H, Liu H, Jia H, Sun J, et al. [Quantity and apoptosis-related protein level of B lymphocyte in patients with immunorelated pancytopenia]. Zhonghua Xue Ye Xue Za Zhi. 2002;23:236-8 pubmed
    To examine the quantity and apoptosis-related protein level of B lymphocyte in the patients with immunorelated pancytopenia (IRP) and explore the role of B lymphocyte in the pathogenetic mechanism of IRP...