decontamination

Summary

Summary: The removal of contaminating material, such as radioactive materials, biological materials, or CHEMICAL WARFARE AGENTS, from a person or object.

Top Publications

  1. ncbi Decontamination of surgical instruments from prions. II. In vivo findings with a model system for testing the removal of scrapie infectivity from steel surfaces
    Karin Lemmer
    P24, Transmissible Spongiform Encephalopathies, Robert Koch Institut, Nordufer 20, 13353 Berlin, Germany
    J Gen Virol 89:348-58. 2008
  2. pmc Evaluation of a hand-held far-ultraviolet radiation device for decontamination of Clostridium difficile and other healthcare-associated pathogens
    Michelle M Nerandzic
    Research Service, Louis Stokes Cleveland Veterans Affairs Medical Center, Cleveland, OH, USA
    BMC Infect Dis 12:120. 2012
  3. ncbi Room decontamination with UV radiation
    William A Rutala
    Hospital Epidemiology, University of North Carolina Health Care, and the Division of Infectious Diseases, University of North Carolina School of Medicine, Chapel Hill, NC 27599 7030, USA
    Infect Control Hosp Epidemiol 31:1025-9. 2010
  4. ncbi Position paper update: gastric lavage for gastrointestinal decontamination
    B E Benson
    American Academy of Clinical Toxicology, McLean, VA, USA
    Clin Toxicol (Phila) 51:140-6. 2013
  5. ncbi Changing bacterial ecology during a five-year period of selective intestinal decontamination
    W Lingnau
    Department of Anaesthesia and Intensive Care Medicine, Leopold Franzens University of Innsbruck, Austria
    J Hosp Infect 39:195-206. 1998
  6. ncbi Oral decontamination is cost-saving in the prevention of ventilator-associated pneumonia in intensive care units
    Christianne A Van Nieuwenhoven
    Department of Surgery, Atrium Heerlen, The Netherlands
    Crit Care Med 32:126-30. 2004
  7. pmc An efficient strategy for broad-range detection of low abundance bacteria without DNA decontamination of PCR reagents
    Shy Shin Chang
    Graduate Institute of Clinical Medical Sciences, Department of Medicine, College of Medicine, Chang Gung University, Tao Yuan, Taiwan, Republic of China
    PLoS ONE 6:e20303. 2011
  8. pmc Quantitative method to determine sporicidal decontamination of building surfaces by gaseous fumigants, and issues related to laboratory-scale studies
    Vipin K Rastogi
    U S Army Edgewood Chemical Biological Center, Aberdeen Proving Grounds, Maryland 21010, USA
    Appl Environ Microbiol 75:3688-94. 2009
  9. ncbi Environmental decontamination of a hospital isolation room using high-intensity narrow-spectrum light
    M MacLean
    Robertson Trust Laboratory for Electronic Sterilisation Technologies ROLEST, University of Strathclyde, Glasgow, UK
    J Hosp Infect 76:247-51. 2010
  10. ncbi Decontamination of the digestive tract and oropharynx in ICU patients
    A M G A de Smet
    Division of Perioperative and Emergency Care, University Medical Center, Utrecht, The Netherlands
    N Engl J Med 360:20-31. 2009

Detail Information

Publications293 found, 100 shown here

  1. ncbi Decontamination of surgical instruments from prions. II. In vivo findings with a model system for testing the removal of scrapie infectivity from steel surfaces
    Karin Lemmer
    P24, Transmissible Spongiform Encephalopathies, Robert Koch Institut, Nordufer 20, 13353 Berlin, Germany
    J Gen Virol 89:348-58. 2008
    ..causing transmissible spongiform encephalopathies (TSEs) to chemical or thermal inactivation requires special decontamination procedures in order to prevent accidental transmission of these pathogens by surgical instruments...
  2. pmc Evaluation of a hand-held far-ultraviolet radiation device for decontamination of Clostridium difficile and other healthcare-associated pathogens
    Michelle M Nerandzic
    Research Service, Louis Stokes Cleveland Veterans Affairs Medical Center, Cleveland, OH, USA
    BMC Infect Dis 12:120. 2012
    ..The Sterilray™ Disinfection Wand device is a hand-held room decontamination technology that utilizes far-ultraviolet radiation (185-230 nm) to kill pathogens.
  3. ncbi Room decontamination with UV radiation
    William A Rutala
    Hospital Epidemiology, University of North Carolina Health Care, and the Division of Infectious Diseases, University of North Carolina School of Medicine, Chapel Hill, NC 27599 7030, USA
    Infect Control Hosp Epidemiol 31:1025-9. 2010
    ..To determine the effectiveness of a UV-C-emitting device to eliminate clinically important nosocomial pathogens in a contaminated hospital room...
  4. ncbi Position paper update: gastric lavage for gastrointestinal decontamination
    B E Benson
    American Academy of Clinical Toxicology, McLean, VA, USA
    Clin Toxicol (Phila) 51:140-6. 2013
    ..This second update summarizes the 2004 content and reviews new data...
  5. ncbi Changing bacterial ecology during a five-year period of selective intestinal decontamination
    W Lingnau
    Department of Anaesthesia and Intensive Care Medicine, Leopold Franzens University of Innsbruck, Austria
    J Hosp Infect 39:195-206. 1998
    The development of bacterial resistance during selective decontamination of the digestive tract (SDD) is controversial...
  6. ncbi Oral decontamination is cost-saving in the prevention of ventilator-associated pneumonia in intensive care units
    Christianne A Van Nieuwenhoven
    Department of Surgery, Atrium Heerlen, The Netherlands
    Crit Care Med 32:126-30. 2004
    ..increase costs of intensive care unit stay, it is unknown whether prevention of VAP by means of oropharyngeal decontamination is cost-effective...
  7. pmc An efficient strategy for broad-range detection of low abundance bacteria without DNA decontamination of PCR reagents
    Shy Shin Chang
    Graduate Institute of Clinical Medical Sciences, Department of Medicine, College of Medicine, Chang Gung University, Tao Yuan, Taiwan, Republic of China
    PLoS ONE 6:e20303. 2011
    ..Although several DNA decontamination protocols have been reported, they all suffer from compromised PCR efficiency or detection limits...
  8. pmc Quantitative method to determine sporicidal decontamination of building surfaces by gaseous fumigants, and issues related to laboratory-scale studies
    Vipin K Rastogi
    U S Army Edgewood Chemical Biological Center, Aberdeen Proving Grounds, Maryland 21010, USA
    Appl Environ Microbiol 75:3688-94. 2009
    ..In summary, a high-throughput quantitative method was developed for determining the efficacies of fumigants, and the spore recoveries from five porous materials and one nonporous material ranged between 20 and 80%...
  9. ncbi Environmental decontamination of a hospital isolation room using high-intensity narrow-spectrum light
    M MacLean
    Robertson Trust Laboratory for Electronic Sterilisation Technologies ROLEST, University of Strathclyde, Glasgow, UK
    J Hosp Infect 76:247-51. 2010
    The performance of a new decontamination technology, referred to as 'high-intensity narrow-spectrum light environmental decontamination system' (HINS-light EDS) was evaluated by a series of three studies carried out in a hospital ..
  10. ncbi Decontamination of the digestive tract and oropharynx in ICU patients
    A M G A de Smet
    Division of Perioperative and Emergency Care, University Medical Center, Utrecht, The Netherlands
    N Engl J Med 360:20-31. 2009
    Selective digestive tract decontamination (SDD) and selective oropharyngeal decontamination (SOD) are infection-prevention measures used in the treatment of some patients in intensive care, but reported effects on patient outcome are ..
  11. ncbi Cutaneous challenge with chemical warfare agents in the SKH-1 hairless mouse. (I) Development of a model for screening studies in skin decontamination and protection
    F Dorandeu
    Département de toxicologie et risque chimique, Institut de Recherche Biomédicale des Armées, Centre de Recherches du Service de Sante des Armees, La Tronche, France
    Hum Exp Toxicol 30:470-90. 2011
    ..Although efficient means of decontamination are available, most of them lose their efficacy when decontamination is delayed after exposure of the bare ..
  12. ncbi Decontamination of deep dentin by means of erbium, chromium:yttrium-scandium-gallium-garnet laser irradiation
    Rene Franzen
    Department for Conservative Dentistry, Periodontology and Preventive Dentistry ZPP, RWTH Aachen University, Aachen, Germany
    Lasers Med Sci 24:75-80. 2009
    ..05). Scanning electron microscopy (SEM) micrographs of the contaminated and irradiated surfaces showed the absence of a smear layer and opened dentinal tubules...
  13. ncbi Implant decontamination during surgical peri-implantitis treatment: a randomized, double-blind, placebo-controlled trial
    Yvonne C M de Waal
    Center for Dentistry and Oral Hygiene, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
    J Clin Periodontol 40:186-95. 2013
    The objective of this randomized, double-blind, placebo-controlled trial was to study the effect of implant surface decontamination with chlorhexidine (CHX)/cetylpyridinium chloride (CPC) on microbiological and clinical parameters.
  14. pmc A study of the perceived risks, benefits and barriers to the use of SDD in adult critical care units (the SuDDICU study)
    B H Cuthbertson
    Department of Critical Care Medicine, Sunnybrook Health Sciences Centre, 2075 Bayview Av, Toronto, Ontario, Canada
    Trials 11:117. 2010
    ..Selective decontamination of the digestive tract (SDD) may reduce these infections and improve mortality but it has not been widely ..
  15. ncbi Processing of cardiovascular allografts: effectiveness of European Homograft Bank (EHB) antimicrobial treatment (cool decontamination protocol with low concentration of antibiotics)
    M Tabaku
    European Homograft Bank, International Association, Brussels, Belgium
    Cell Tissue Bank 5:261-6. 2004
    To assess the effectiveness of antimicrobial treatment by using cool decontamination protocol with low concentration of antibiotics during processing of cardiovascular allografts, 948 allografts processed during a 2-year period were ..
  16. ncbi Dealing with the aftermath of Fukushima Daiichi nuclear accident: decontamination of radioactive cesium enriched ash
    Durga Parajuli
    National Institute of Advanced Industrial Science and Technology AIST, 1 1 1 Higashi, Tsukuba, 305 8565, Japan
    Environ Sci Technol 47:3800-6. 2013
    ..Once the Cs in solids is extracted to the solution, it can be loaded to Cs selective adsorbents such as Prussian blue and safely stored in a small volume...
  17. ncbi Tackling contamination of the hospital environment by methicillin-resistant Staphylococcus aureus (MRSA): a comparison between conventional terminal cleaning and hydrogen peroxide vapour decontamination
    G L French
    Department of Infection, King s College London, North Wing, St Thomas Hospital, UK
    J Hosp Infect 57:31-7. 2004
    ..by MRSA, and compared the effectiveness of standard cleaning with a new method of hydrogen peroxide vapour decontamination. MRSA contamination, measured by surface swabbing was compared before and after terminal cleaning that ..
  18. pmc Effects of decontamination, DNA extraction, and amplification procedures on the molecular diagnosis of Mycobacterium ulcerans disease (Buruli ulcer)
    Dissou Affolabi
    Laboratoire de Référence des Mycobactéries, Cotonou, Benin
    J Clin Microbiol 50:1195-8. 2012
    ..All of these procedures were compared before and after decontamination. We observed that, among the procedures tested, real-time PCR after the modified Boom extraction method or a ..
  19. ncbi Non-thermal plasma technologies: new tools for bio-decontamination
    M Moreau
    Laboratory of Cold Microbiology, UPRES EA 2123, University of Rouen, Evreux, France
    Biotechnol Adv 26:610-7. 2008
    Bacterial control and decontamination are crucial to industrial safety assessments. However, most recently developed materials are not compatible with standard heat sterilization treatments...
  20. pmc Biodegradation of ochratoxin a for food and feed decontamination
    Luís Abrunhosa
    IBB, Institute for Biotechnology, Bioengineering, Centro de Engenharia Biólogica, Universidade do Minho, Campus de Gualtar, Braga, Portugal
    Toxins (Basel) 2:1078-99. 2010
    ..A critical discussion about the technical applicability of these strategies is presented...
  21. ncbi Effect of saliva contamination and decontamination on bovine enamel bond strength of four self-etching adhesives
    Qin Jiang
    No 1 Hospital Aff to Medical College, Zhejiang University, Stomatology, Hangzhou, Zhejiang, China
    Oper Dent 35:194-202. 2010
    ..This study evaluated the effect of saliva contamination on the bovine enamel microtensile bond strengths (microTBS) of four self-etching adhesives...
  22. ncbi Surface decontamination of surgical instruments: an ongoing dilemma
    H Murdoch
    Centre for Emergency Preparedness and Response Laboratory A, Health Protection Agency, Porton Down, Salisbury, UK
    J Hosp Infect 63:432-8. 2006
    ....
  23. ncbi Decontamination of prion protein (BSE301V) using a genetically engineered protease
    J Dickinson
    Health Protection Agency, Porton Down, Salisbury, UK
    J Hosp Infect 72:65-70. 2009
    ..This study demonstrates the potential for thermostable proteases to be developed as effective inactivation processes for prion agents in healthcare management...
  24. ncbi Selective digestive tract decontamination and selective oropharyngeal decontamination and antibiotic resistance in patients in intensive-care units: an open-label, clustered group-randomised, crossover study
    Anne Marie G A de Smet
    Division of Perioperative and Emergency Care, University Medical Centre Utrecht, Utrecht, The Netherlands
    Lancet Infect Dis 11:372-80. 2011
    Previously, we assessed selective digestive tract decontamination (SDD) and selective oropharyngeal decontamination (SOD) on survival and prevention of bacteraemia in patients in intensive-care units...
  25. ncbi Comparison of different decontamination methods for reagents to detect low concentrations of bacterial 16S DNA by real-time-PCR
    Sven Klaschik
    Klinik und Poliklinik fur Anasthesiologie und spezielle Intensivmedizin, Universitat Bonn, Sigmund Freud Strasse 25, D 53105 Bonn, Germany
    Mol Biotechnol 22:231-42. 2002
    ..We have tested four different methods of decontamination of PCR reagents in a project aimed at detecting bacterial DNA at low concentrations: deoxyribonuclease (DNAse)..
  26. ncbi Randomized controlled trial and meta-analysis of oral decontamination with 2% chlorhexidine solution for the prevention of ventilator-associated pneumonia
    Hutsaya Tantipong
    Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand
    Infect Control Hosp Epidemiol 29:131-6. 2008
    To determine the effectiveness of oral decontamination with 2% chlorhexidine solution for the prevention of ventilator-associated pneumonia (VAP).
  27. ncbi Impact of hydrogen peroxide vapor room decontamination on Clostridium difficile environmental contamination and transmission in a healthcare setting
    John M Boyce
    Hospital of St Raphael, Yale University School of Medicine, New Haven, Connecticut 06511, USA
    Infect Control Hosp Epidemiol 29:723-9. 2008
    To determine whether hydrogen peroxide vapor (HPV) decontamination can reduce environmental contamination with and nosocomial transmission of Clostridium difficile.
  28. pmc A standardized comparison of commercially available prion decontamination reagents using the Standard Steel-Binding Assay
    Julie Ann Edgeworth
    MRC Prion Unit, Department of Neurodegenerative Disease, UCL Institute of Neurology, Queen Square, London WC1N 3BG, UK
    J Gen Virol 92:718-26. 2011
    ..transfer infectivity to a suitable host, and much research has been performed to achieve effective prion decontamination of metal surfaces...
  29. pmc Antibiotics or probiotics as preventive measures against ventilator-associated pneumonia: a literature review
    Marcus J Schultz
    Department of Intensive Care Medicine, Academic Medical Center, University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands
    Crit Care 15:R18. 2011
    ..Proposed preventive measures against VAP include, but are not restricted to, selective decontamination of the digestive tract (SDD), selective oropharyngeal decontamination (SOD) and the use of probiotics...
  30. pmc Evaluation of an automated ultraviolet radiation device for decontamination of Clostridium difficile and other healthcare-associated pathogens in hospital rooms
    Michelle M Nerandzic
    Research Service, Louis Stokes Cleveland Veterans Affairs Medical Center, 10701 East Boulevard, Cleveland, Ohio, USA
    BMC Infect Dis 10:197. 2010
    ..Environmental surfaces play an important role in transmission of healthcare-associated pathogens. There is a need for new disinfection methods that are effective against Clostridium difficile spores, but also safe, rapid, and automated...
  31. ncbi Lethal photosensitization for decontamination of implant surfaces in the treatment of peri-implantitis
    O Dörtbudak
    Department of Oral Surgery, School of Dentistry of the University of Vienna, Vienna, Austria
    Clin Oral Implants Res 12:104-8. 2001
    ..The application of TBO and laser resulted in a significant reduction (P<0.0001) of the initial values in all 3 groups of bacteria. Complete elimination of bacteria was not achieved...
  32. ncbi Reagent decontamination to eliminate false-positives in Escherichia coli qPCR
    Sarah S Silkie
    Civil and Environmental Engineering Department, University of California, Berkeley, CA 94720 1710, USA
    J Microbiol Methods 72:275-82. 2008
    ..coli and other bacterial DNA. We optimized a DNase I decontamination method to eliminate false-positives in a qPCR assay targeting the uidA gene in E. coli...
  33. ncbi Comparison of NaOH-N-acetyl cysteine and sulfuric acid decontamination methods for recovery of mycobacteria from clinical specimens
    Patricia C A M Buijtels
    Medical Centre Rijnmond South, Location Clara, Department of Medical Microbiology, Olympiaweg 350, 3078 HT, Rotterdam, The Netherlands
    J Microbiol Methods 62:83-8. 2005
    We compared the NaOH-N-acetyl cysteine (NaOH-NALC) and the sulfuric acid decontamination procedure in the detection of mycobacteria using the Mycobacteria Growth Indicator Tube (MGIT)...
  34. ncbi Selective decontamination of digestive tract in intensive care
    Mohit Sahni
    Lancet 362:2119; author reply 2119-20. 2003
  35. ncbi [Study of the metal precipitation from decontamination leachates of municipal wastes fly ash incinerators]
    B Levasseur
    Institut national de la Recherche Scientifique Centre Eau, Terre et Environnement, Universite du Quebec, 490 rue de la Couronne, Quebec, QC, Canada, G1K 9A9
    Environ Technol 26:421-31. 2005
    This research work focuses on the development of a new process for the decontamination of municipal wastes incinerators fly ashes...
  36. ncbi Influence of severity of illness, medication and selective decontamination on defecation
    Johan I van der Spoel
    Onze Lieve Vrouwe Gasthuis, Department of Intensive Care, Oosterpark 9, 1091 AC Amsterdam, The Netherlands
    Intensive Care Med 32:875-80. 2006
    To describe the pattern of defecation in critically ill ventilated patients and the influence of selective decontamination (SDD) and other medication.
  37. ncbi Effects of decontamination and implant surface characteristics on re-osseointegration following treatment of peri-implantitis
    Ates Parlar
    Department of Periodontology, Faculty of Dentistry, Gazi University, Ankara, Turkey
    Clin Oral Implants Res 20:391-9. 2009
    ..Although considerable bone fill may occur following treatment of peri-implantitis, re-osseointegration appears to be limited and unpredictable...
  38. ncbi Relevant factors affecting microbial surface decontamination by pulsed light
    Caroline Levy
    Claranor S A, Chemin de la Rollande, Agroparc, BP 21 531, F 84916 Avignon cedex 9, France
    Int J Food Microbiol 152:168-74. 2012
    Pulsed Light (PL) uses intense flashes of white light rich in ultraviolet (UV) light for decontamination. A log-reduction higher than 5 was obtained in one flash and at fluences lower than 1...
  39. pmc Single-drug therapy or selective decontamination of the digestive tract as antifungal prophylaxis in critically ill patients: a systematic review
    Jw Olivier van Till
    Department of Surgery, Academic Medical Center, PO Box 22660, 1100 DD Amsterdam, The Netherlands
    Crit Care 11:R126. 2007
    ..The objective of this study was to determine and compare the effectiveness of different prophylactic antifungal therapies in critically ill patients on the incidence of yeast colonisation, infection, candidemia, and hospital mortality...
  40. ncbi Decontamination of rooms, medical equipment and ambulances using an aerosol of hydrogen peroxide disinfectant
    B M Andersen
    Department of Hospital Infection, Ulleval University Hospital, Oslo, Norway
    J Hosp Infect 62:149-55. 2006
    ..Gloster Sante Europe) providing a dry fume of 5% hydrogen peroxide (H(2)O(2)) disinfectant was tested for decontamination of rooms, ambulances and different types of medical equipment...
  41. pmc Systematic evaluation of the efficacy of chlorine dioxide in decontamination of building interior surfaces contaminated with anthrax spores
    Vipin K Rastogi
    Research and Technology Directorate, U S Army, Edgewood Chemical Biological Center, Aberdeen Proving Ground, MD 21010, USA
    Appl Environ Microbiol 76:3343-51. 2010
    ..5 and 12 h) were used to evaluate the relative role of fumigant exposure period and total dose in the decontamination of building surfaces...
  42. ncbi Antibiotic resistance may affect alkali decontamination of specimens containing mycobacteria
    Hasan Yesilkaya
    Department of Infection, Immunity, and Inflammation, Leicester Medical School, University of Leicester, United Kingdom
    Diagn Microbiol Infect Dis 50:153-5. 2004
    The influence of genetic modification on the decontamination process of mycobacteria was investigated using a wild type Mycobacterium bovis BCG Pasteur and its isogenic mutant strain...
  43. ncbi Effects on instruments of the World Health Organization--recommended protocols for decontamination after possible exposure to transmissible spongiform encephalopathy-contaminated tissue
    Stanley A Brown
    United States Food and Drug Administration, Center of Devices and Radiological Health, Office of Science and Technology, Rockville, MD 20850, USA
    J Biomed Mater Res B Appl Biomater 72:186-90. 2005
    ..by the World Health Organization (WHO) and Centers for Disease Control and Prevention (CDC) that rigorous decontamination protocols be used on surgical instruments that have been exposed to tissue possibly contaminated with ..
  44. ncbi A novel copper-hydrogen peroxide formulation for prion decontamination
    Jerome Solassol
    Institut de Genetique Humaine du Centre National de la Recherche Scientifique, UPR1142, 34396 Montpellier, France
    J Infect Dis 194:865-9. 2006
    ..the detection of infectious prions in the peripheral organs of persons with sporadic CJD, the development of decontamination methods that are compatible with medical equipment has become a major issue...
  45. ncbi Efficacy of high-intensity pulsed light for the microbiological decontamination of chicken, associated packaging, and contact surfaces
    Pippa N Haughton
    Institute of Food and Health, School of Agriculture, Food Science, and Veterinary Medicine, University College Dublin, Dublin, Ireland
    Foodborne Pathog Dis 8:109-17. 2011
    ..light pulse (HILP) technology (3 Hz, maximum of 505 J/pulse, and a pulse duration of 360 μs) for the decontamination of raw chicken and associated packaging and surface materials was investigated...
  46. ncbi Decontamination of the environment
    Adam P Fraise
    Hospital Infection Research Laboratory, City Hospital, Birmingham, UK
    J Hosp Infect 65:58-9. 2007
  47. pmc The effect of decontamination procedures on the pharmacodynamics of venlafaxine in overdose
    Venkata V Pavan Kumar
    School of Pharmacy, University of Otago, Dunedin, New Zealand
    Br J Clin Pharmacol 72:125-32. 2011
    To investigate the relationship between decontamination procedures and seizure events caused by venlafaxine overdose and to estimate the time at which 90% of patients would have had their first seizure in the presence and absence of ..
  48. ncbi Decontamination of vegetables sprayed with organophosphate pesticides by organophosphorus hydrolase and carboxylesterase (B1)
    Y Z Zheng
    State Key Laboratory of Integrated Management of Pest Insects and Rodents, Institute of Zoology, Chinese Academy of Sciences, Beijing 100080, China
    Appl Biochem Biotechnol 136:233-41. 2007
    ..Additionally, the products of pesticide hydrolysis generated by treatment with the enzyme extract were determined to be virtually nontoxic...
  49. ncbi Availability of decontamination, elimination enhancement, and stabilization resources for the management of acute toxic exposures and poisonings in emergency departments in Malaysia
    Rahmat Awang
    WHO Collaborating Centre for Drug Information, Clinical Toxicology Program, National Poison Centre, Universiti Sains Malaysia USM, 11800 Penang, Malaysia
    Intern Emerg Med 6:441-8. 2011
    ..be saved if the patient is diagnosed properly and receives the appropriate treatment such as gastrointestinal decontamination techniques and resources to increase poison elimination according to clinical guidelines at a reasonable time...
  50. ncbi [Comparison of BBL Mycoprep and 2%NaOH decontamination procedures for MGIT]
    Motohisa Tomita
    Department of Clinical Laboratory, National Hospital Organization Kinki chuo Chest Medical Center, Japan
    Kekkaku 83:471-3. 2008
    We compared the BBL Mycoprep (Becton Dickinson Japan) and home-made 2%NaOH decontamination procedures by using an equal amount of expectorated sputum in the aerosol-free 30 ml KT centrifuge tube with the rugged inner surface.
  51. pmc Cost and effectiveness of decontamination strategies in radiation contaminated areas in Fukushima in regard to external radiation dose
    Tetsuo Yasutaka
    National Institute of Advanced Industrial Science and Technology AIST, Institute for Geo Resources and Environment GREEN, Higashi, Tsukuba, Japan
    PLoS ONE 8:e75308. 2013
    The objective of the present study is to evaluate the cost and effectiveness of decontamination strategies in the special decontamination areas in Fukushima in regard to external radiation dose...
  52. pmc Decontamination of targeted pathogens from patient rooms using an automated ultraviolet-C-emitting device
    Deverick J Anderson
    Division of Infectious Diseases, Department of Medicine, Duke University Medical Center, Durham, North Carolina, USA
    Infect Control Hosp Epidemiol 34:466-71. 2013
    ..Reductions similarly occurred in direct and indirect line of sight. CONCLUSIONS. Our data confirm that automated UV-C-emitting devices can decrease the bioburden of important pathogens in real-world settings such as hospital rooms...
  53. ncbi Novel hypertonic saline-sodium hydroxide (HS-SH) method for decontamination and concentration of sputum samples for Mycobacterium tuberculosis microscopy and culture
    Christian A Ganoza
    Laboratorio de Microbiologia Clinica, Instituto de Medicina Tropical Alexander von Humboldt, Universidad Peruana Cayetano Heredia, and Programa Nacional para el Control de la Tuberculosis, Hospital Nacional Cayetano Heredia, Lima, Peru
    J Med Microbiol 57:1094-8. 2008
    This study evaluated a new decontamination and concentration (DC) method for sputum microscopy and culture...
  54. ncbi Comparison of decontamination methods for primary isolation of Mycobacterium bovis in paucibacillary bovine tissues
    L Medeiros
    Universidade Federal Fluminense, Laboratório de Bacteriologia Veterinária, Rua Hernani Mello, Niteroi RJ, Brazil
    Lett Appl Microbiol 54:182-6. 2012
    To compare three decontamination methods applied to paucibacillary samples for primary isolation of Mycobacterium bovis from suspect lesions. Tuberculosis caused by Myco...
  55. ncbi A GIS-based evaluation of the effect of decontamination on effective doses due to long-term external exposures in Fukushima
    Tetsuo Yasutaka
    National Institute of Advanced Industrial Science and Technology, 1 1 1, Higashi, Tsukuba, Ibaraki 305 8567, Japan Electronic address
    Chemosphere 93:1222-9. 2013
    Despite the enormous cost of radiation decontamination, there has been almost no quantitative discussion on how much it would reduce the long-term external radiation exposure in the Evacuation Zone and Planned Evacuation Zone (restricted ..
  56. ncbi Effect of selective decontamination on antimicrobial resistance in intensive care units: a systematic review and meta-analysis
    Nick Daneman
    Trauma, Emergency, and Critical Care Program, Sunnybrook Health Sciences Centre, University of Toronto, ON, Canada
    Lancet Infect Dis 13:328-41. 2013
    ..have shown reductions in infection rates and mortality associated with the use of selective digestive decontamination (SDD) or selective oropharyngeal decontamination (SOD) in intensive care units (ICUs)...
  57. ncbi Investigations into the application of a combination of bioventing and biotrickling filter technologies for soil decontamination processes--a transition regime between bioventing and soil vapour extraction
    S M C Magalhães
    CBQF Escola Superior de Biotecnologia, Universidade Catolica Portuguesa, Rua Dr Antonio Bernardino de Almeida, 4200 072 Porto, Portugal
    J Hazard Mater 170:711-5. 2009
    ..86%. The proposed combination of biotechnologies proved to be an efficient solution for the decontamination process, when an excessive air flow rate was applied, reducing both the soil contamination and the outlet gas ..
  58. ncbi Nanoindentation of orthodontic archwires: The effect of decontamination and clinical use on hardness, elastic modulus and surface roughness
    Joseph P Alcock
    Division of Child Dental Health, Bristol Dental School, University of Bristol, Bristol, UK
    Dent Mater 25:1039-43. 2009
    The purpose of this research was to investigate the effects of decontamination and clinical exposure on the elastic moduli, hardness and surface roughness of two frequently used orthodontic archwires, namely 0.020in.x0.020in...
  59. ncbi For whom should we use selective decontamination of the digestive tract?
    Anne Marie G A de Smet
    Department of Critical Care, University Medical Center Groningen, The University of Groningen, The Netherlands
    Curr Opin Infect Dis 25:211-7. 2012
    This review discusses the relevant studies on selective decontamination of the digestive tract (SDD) published between 2009 and mid-2011.
  60. pmc Decontamination efficiencies of pot-type water purifiers for ¹³¹I, ¹³⁴Cs and ¹³⁷Cs in rainwater contaminated during Fukushima Daiichi nuclear disaster
    Shogo Higaki
    Radioisotope Center, The University of Tokyo, Tokyo, Japan
    PLoS ONE 7:e37184. 2012
    ..In the present study, the decontamination efficiency of two easily obtainable commercial water purifiers were examined for rainwater contaminated with ..
  61. ncbi Combined surgical therapy of peri-implantitis evaluating two methods of surface debridement and decontamination. A two-year clinical follow up report
    Frank Schwarz
    Department of Oral Surgery, Heinrich Heine University, Dusseldorf, Germany
    J Clin Periodontol 39:789-97. 2012
    The study aimed at evaluating the 2-year results obtained following combined surgical resective and regenerative treatment of advanced peri-implantitis defects comparing two methods of surface debridement/decontamination (DD).
  62. pmc Effects of relative humidity and spraying medium on UV decontamination of filters loaded with viral aerosols
    Myung Heui Woo
    Department of Environmental Engineering Sciences, University of Florida, Gainesville, Florida, USA
    Appl Environ Microbiol 78:5781-7. 2012
    ..The objective of this study was to determine the effects of transmission mode and environmental conditions on decontamination efficiency by UV...
  63. ncbi Susceptibility of Campylobacter to high intensity near ultraviolet/visible 395±5nm light and its effectiveness for the decontamination of raw chicken and contact surfaces
    Pippa N Haughton
    School of Veterinary Medicine, Physiotherapy and Population Science, University College Dublin, Belfield, Dublin 4, Ireland
    Int J Food Microbiol 159:267-73. 2012
    ..near ultraviolet/visible (NUV-vis) 395±5nm light and to examine its potential for the microbiological decontamination of raw chicken and contact surfaces...
  64. ncbi Bioremediation of trace cobalt from simulated spent decontamination solutions of nuclear power reactors using E. coli expressing NiCoT genes
    G Raghu
    Department of Biochemistry, Osmania University, Hyderabad, 500 007, India
    Appl Microbiol Biotechnol 81:571-8. 2008
    ..presence of large excess (10(6)-fold) of corrosion product ions of complexed Fe, Cr, and Ni in spent chemical decontamination formulations (simulated effluent) of nuclear reactors is currently done by using synthetic organic ion ..
  65. ncbi Comparison of the microbiological efficacy of hydrogen peroxide vapor and ultraviolet light processes for room decontamination
    Nancy L Havill
    Hospital of Saint Raphael, New Haven, Connecticut 06511, USA
    Infect Control Hosp Epidemiol 33:507-12. 2012
    To compare the microbiological efficacy of hydrogen peroxide vapor (HPV) and ultraviolet radiation (UVC) for room decontamination.
  66. ncbi Oral topical decontamination for preventing ventilator-associated pneumonia: a systematic review and meta-analysis of randomized controlled trials
    J Li
    Department of Geriatrics, West China Hospital, Sichuan University, Chengdu, Sichuan Province, China
    J Hosp Infect 84:283-93. 2013
    Oral decontamination is proposed to be an effective prevention of ventilator-associated pneumonia (VAP).
  67. ncbi Selective digestive decontamination: for everyone, everywhere?
    Jean Louis Vincent
    Department of Intensive Care, Erasme Hospital, Free University of Brussels, 1070, Brussels, Belgium
    Lancet 362:1006-7. 2003
  68. ncbi Organophosphate skin decontamination using immobilized enzymes
    R K Gordon
    Walter Reed Army Institute of Research, Division of Biochemistry, Washington, DC 20307, USA
    Chem Biol Interact 119:463-70. 1999
    ..the applicability of OP scavengers from in vivo protection, to a variety of external detoxification and decontamination schemes...
  69. ncbi Gaseous and air decontamination technologies for Clostridium difficile in the healthcare environment
    A Davies
    Centre for Emergency Preparedness and Response, Health Protection Agency, Porton Down, Salisbury, Wiltshire, UK
    J Hosp Infect 77:199-203. 2011
    ..Alternative disinfection technologies such as gaseous decontamination are currently being marketed to the healthcare sector as an alternative/supplement to manual disinfection, ..
  70. ncbi Evaluation of decontamination process of heart valve and artery tissues in European Homograft Bank (EHB): a retrospective study of 1,055 cases
    Ye Dong Fan
    European Homograft Bank EHB, International Association, c o Military Hospital Queen Astrid, Brussels, Belgium
    Cell Tissue Bank 13:297-304. 2012
    To evaluate the efficiency of decontamination practice in European Homograft Bank (EHB), the data of the cardiovascular tissues received during recent 2 years were retrospectively analysed in this study...
  71. doi Prevention of ventilator-associated pneumonia by selective decontamination of the digestive tract
    L Silvestri
    Eur Respir J 32:241-3. 2008
  72. ncbi Active surveillance testing and decontamination strategies in intensive care units to reduce methicillin-resistant Staphylococcus aureus infections
    Asok Kurup
    Department of Infectious Diseases, Singapore General Hospital, Singapore
    Am J Infect Control 38:361-7. 2010
    Active surveillance testing (AST) and decontamination strategies (DS) using a topical methicillin-resistant Staphylococcus aureus (MRSA) cleansing agent was introduced in July 2007 in a medical intensive care unit (MICU) and a surgical ..
  73. ncbi Assessing the biological efficacy and rate of recontamination following hydrogen peroxide vapour decontamination
    J A Otter
    BIOQUELL UK Ltd, Andover, Hampshire, UK
    J Hosp Infect 67:182-8. 2007
    ..Hydrogen peroxide vapour (HPV) decontamination has proven effective for the eradication of persistent environmental contamination...
  74. ncbi Immobilization of Russian VX skin depots by localized cooling: implications for decontamination and medical countermeasures
    J Mikler
    Defence Research and Development Canada Suffield, Box 4000, Medicine Hat, Alberta, Canada T1A8K6
    Toxicol Lett 206:47-53. 2011
    ..b>Decontamination with the Reactive Skin Decontaminant Lotion (RSDL) 15 min after VR exposure was completely effective in ..
  75. ncbi Comparative analysis of showering protocols for mass-casualty decontamination
    Richard Amlot
    Health Protection Agency, Salisbury, Wiltshire, UK
    Prehosp Disaster Med 25:435-9. 2010
    A well-established provision for mass-casualty decontamination that incorporates the use of mobile showering units has been developed in the UK...
  76. ncbi [Hygiene and methods of decontamination, disinfection and sterilization in dental offices in Yaounde]
    J Onana
    Service d odonto stomatologie, Hôpital Militaire de Yaoundé, BP 1162 Yaoundé, Cameroun
    Odontostomatol Trop 25:45-51. 2002
    ..The ways of cleaning, decontamination, disinfection or of sterilization of the premises, the dental equipment and instruments, hand-washing, ..
  77. pmc Chemical, physical and biological approaches to prevent ochratoxin induced toxicoses in humans and animals
    Janos Varga
    Department of Microbiology, Faculty of Science and Informatics, University of Szeged, Közép fasor 52, H 6726 Szeged, Hungary
    Toxins (Basel) 2:1718-50. 2010
    ..These strategies can be classified into three main categories: prevention of ochratoxin contamination, decontamination or detoxification of foods contaminated with ochratoxins, and inhibition of the absorption of consumed ..
  78. ncbi Decontamination of pork carcasses during scalding and the prevention of Salmonella cross-contamination
    D J Bolton
    The National Food Centre, Ashtown, Dublin 15, Republic of Ireland
    J Appl Microbiol 94:1036-42. 2003
    ..The objective of this study was to establish critical temperature limits to prevent cross-contamination of pork carcasses during scalding...
  79. ncbi The challenge of prion decontamination
    Gerald McDonnell
    Steris, Basingstoke, Hampshire, United Kingdom
    Clin Infect Dis 36:1152-4. 2003
  80. ncbi Influence of decontamination procedures on shear forces after contamination with blood or saliva
    Lorenz Brauchli
    Clinic of Orthodontics and Pedodontics, University of Basel, Basel, Switzerland
    Am J Orthod Dentofacial Orthop 138:435-41. 2010
    ..The aims of this study were to evaluate the influence of contamination on bond strength and to investigate possible decontamination procedures.
  81. ncbi Evaluation of the decontamination efficacy of new and reprocessed microfiber cleaning cloth compared with other commonly used cleaning cloths in the hospital
    Magda Diab-Elschahawi
    Clinical Institute for Hygiene and Medical Microbiology, Division for Hospital Hygiene, Vienna General Hospital, Medical University of Vienna, Waehringer Guertel 18 20, Vienna, Austria
    Am J Infect Control 38:289-92. 2010
    The aim of this study was to investigate the decontamination capacity of 4 different types of cleaning cloths (microfiber cleaning cloth, cotton cloth, sponge cloth, and disposable paper towels) commonly used in hospital in their ability ..
  82. ncbi Truth hurts--hard lessons from Australia's largest mass casualty exercise with contaminated patients
    Nicholas A Edwards
    Intensive Care Unit, Royal Adelaide Hospital, Adelaide, South Australia, Australia
    Emerg Med Australas 18:185-95. 2006
    ..by the exercise, which we believe have enormous implications for the development of hospital chemical, biological or radiological plans and the likelihood of their success--hospital security, crowd control and decontamination.
  83. ncbi Decontamination of grains and legumes infected with Aspergillus spp. and Penicillum spp. by cold plasma treatment
    Meral Selcuk
    Department of Food Engineering, Suleyman Demirel University, Isparta, Turkey
    Bioresour Technol 99:5104-9. 2008
    ..and Penicillum spp. artificially contaminated on seed surface. The plasma decontamination process was performed by batch process in vacuum chamber, using gas injection followed by plasma discharge ..
  84. ncbi Public experiences of mass casualty decontamination
    Holly Carter
    Emergency Response Department, Health Protection Agency, Salisbury, United Kingdom
    Biosecur Bioterror 10:280-9. 2012
    In this article, we analyze feedback from simulated casualties who took part in field exercises involving mass decontamination, to gain an understanding of how responder communication can affect people's experiences of and compliance ..
  85. ncbi In vitro evaluation of different chemical agents for the decontamination of gutta-percha cones
    Rogério Emílio de Souza
    School of Dentistry, University of Ribeirao Preto
    Pesqui Odontol Bras 17:75-7. 2003
    This study evaluated the effectiveness of three disinfectants used in Dentistry for decontamination of gutta-percha cones...
  86. ncbi Emergence of multidrug-resistant Gram-negative bacteria during selective decontamination of the digestive tract on an intensive care unit
    Nashwan Al Naiemi
    Academic Medical Center, Department of Medical Microbiology Amsterdam, The Netherlands
    J Antimicrob Chemother 58:853-6. 2006
    During treatment with selective decontamination of the digestive tract (SDD), four multidrug-resistant (MDR) strains, three different Escherichia coli and one Klebsiella pneumoniae, were isolated from four patients not known as carriers ..
  87. ncbi Effect of contamination and decontamination on adhesion of a resin-modified glass-ionomer cement to bovine dentin
    Pitsapaporn Wangpermtam
    Department of Oral Rehabilitation, The University of Hong Kong, Hong Kong
    J Adhes Dent 13:445-53. 2011
    ..To determine the adhesion of resin-modified glass-ionomer cement to bovine dentin under contaminated and decontaminated conditions...
  88. ncbi A laboratory evaluation of the decontamination properties of microfibre cloths
    G Moore
    School of Applied Sciences, University of Wales Institute, Cardiff, UK
    J Hosp Infect 64:379-85. 2006
    ..Different makes of microfibre cloths have different characteristics, and the name 'microfibre' should not imply superior cleaning efficacy...
  89. ncbi Response surface methodology-based optimization of decontamination conditions for Escherichia coli O157:H7 and Salmonella Typhimurium on fresh-cut celery using thermoultrasound and calcium propionate
    Tae Yeon Kwak
    Division of Food Bioscience and Technology, Korea University, Seoul, 136 713, South Korea
    Int J Food Microbiol 150:128-35. 2011
    ..coli O157:H7 and S. Typhimurium on fresh-cut celery. Furthermore, this treatment extends fresh storability without physical quality deterioration...
  90. ncbi Long-term use of selective decontamination of the digestive tract does not increase antibiotic resistance: a 5-year prospective cohort study
    María E Ochoa-Ardila
    Intensive Care Unit, Fundación Valle del Lilli, Cali, Colombia
    Intensive Care Med 37:1458-65. 2011
    Despite the evidence, the use of selective decontamination of the digestive tract (SDD) remains controversial, largely because of concerns that it may promote the emergence of antibiotic-resistant strains...
  91. ncbi Microbial contamination of toothbrushes and their decontamination
    P Nelson Filho
    Department of Pediatric Dentistry, School of Dentistry of Ribeirao Preto, University of Sao Paulo, Brazil
    Pediatr Dent 22:381-4. 2000
    ....
  92. ncbi Weapons of mass destruction events with contaminated casualties: effective planning for health care facilities
    A G Macintyre
    Department of Emergency Medicine, George Washington University Medical Center, Washington, DC, USA
    JAMA 283:242-9. 2000
    ..HCF response plan include prompt recognition of the incident, staff and facility protection, patient decontamination and triage, medical therapy, and coordination with external emergency response and public health agencies...
  93. pmc Hypothermia does not increase the risk of infection: a case control study
    Marlijn Kamps
    Department of Intensive Care, Radboud University Nijmegen Medical Centre PO Box 9101, 6500 HB Nijmegen, The Netherlands
    Crit Care 15:R48. 2011
    ..Prolonged hypothermic treatment may further enhance the risk of infection. Selective decontamination of the digestive tract (SDD) reduces the risk of respiratory tract infections...
  94. pmc Impact of digestive and oropharyngeal decontamination on the intestinal microbiota in ICU patients
    Robin F Benus
    Department of Medical Microbiology, University Medical Centre Groningen, University of Groningen, Groningen, The Netherlands
    Intensive Care Med 36:1394-402. 2010
    Selective digestive microbial decontamination (SDD) is hypothesized to benefit patients in intensive care (ICU) by suppressing Gram-negative potential pathogens from the colon without affecting the anaerobic intestinal microbiota...
  95. ncbi Application of a novel decontamination process using gaseous ozone
    John Moat
    University of Manchester School of Medicine, Manchester Royal Infirmary, UK
    Can J Microbiol 55:928-33. 2009
    ..Recently, there has been interest in the use of vapor- and gas-based treatments for decontamination of surfaces and rooms...
  96. ncbi Bacterial contamination and decontamination of toothbrushes after use
    Abhishek Mehta
    Department of Community Dentistry, Jaipur Dental College, India
    N Y State Dent J 73:20-2. 2007
    ..Overnight immersion of a toothbrush in chlorhexidine gluconate (0.2%) was found to be highly effective in preventing such microbial contamination...
  97. ncbi PCNA-expression of cementoblasts and fibroblasts on the root surface after extraoral rinsing for decontamination
    Ulrike Ebensberger
    Department of Oral Surgery, University of Bonn, Bonn, Germany
    Dent Traumatol 18:262-6. 2002
    ..24). Ozonized water, not being isotonic, had no negative effect on periodontal cells remaining on the tooth surface after irrigation for 2 min...
  98. ncbi Cleanability of dental instruments--implications of residual protein and risks from Creutzfeldt-Jakob disease
    J T Walker
    HPA Centre for Emergency Preparedness and Response, Porton Down, Salisbury, SP4 0JG
    Br Dent J 203:395-401. 2007
    ....
  99. ncbi Pulsed-light system as a novel food decontamination technology: a review
    N Elmnasser
    Laboratoire d Analyse, de Traitement et de Valorisation des Polluants de l Environnement et de Produits Faculte de Pharmacie de Monastir, Rue Avicenne, 5000 Monastir, Tunisie
    Can J Microbiol 53:813-21. 2007
    ..It appears to constitute a good alternative or a complement to conventional thermal or chemical decontamination processes...
  100. pmc Improved laboratory safety by decontamination of unstained sputum smears for acid-fast microscopy
    Luiz Roberto Bigão Giacomelli
    Departamento de Analises Clinicas, Universidade Estadual de Maringa, PR, Brazil
    J Clin Microbiol 43:4245-8. 2005
    ..7% for 1 min (tube technique) or for 10 min (slide technique) were effective in decontaminating sputum smears and preserved cell morphology and quantitative acid-fast microscopy results...
  101. ncbi Bone microbial decontamination agents in osseous grafting: an in vitro study with fresh human explants
    Fernando Verdugo
    VA Hospital, Greater Los Angeles, Healthcare System, Los Angeles, CA, USA
    J Periodontol 82:863-71. 2011
    ..Establishing a safe prophylactic antimicrobial protocol in bone grafting may enhance osseous volume outcomes. The purpose of this in vitro study is to assess human osteoblast response and safety after explant antimicrobial exposure...

Research Grants62

  1. Processing of Materials for Improved Biocompatibility
    Michael Matthews; Fiscal Year: 2004
    ..used in biomedical devices such as prostheses and implants by providing a higher level of cleanliness and decontamination, while simultaneously providing sterilization...
  2. Durable Visible Light-activated Antivral Coatings for Fabrics Used for Personal P
    JOSEF STEPHAN SCHNEIDER; Fiscal Year: 2011
    ..Thus, opportunities exist for simple, efficacious decontamination methods that reduce the risk of infection through handling a contaminated respirator and that do not ..
  3. Mucosal Immunity and Microbiota in Intestinal Graft-versus-Host Disease
    Marcel R m van den Brink; Fiscal Year: 2013
    ..intestinal microbial flora and his/her propensity for GVHD, but the translation to the clinic (gut decontamination and/or laminar airflow protective environment) remains controversial...
  4. Nonheme Diiron Centers and the Biological Oxidation of Hydrocarbons
    Stephen J Lippard; Fiscal Year: 2013
    ..The ability of these hydrocarbon-consuming "superbugs" to degrade chlorinated hydrocarbons has led to their application in the bioremediation of industrial wastewater, decontamination of seawater, and removal of soil pollutants.
  5. CFI Inactivation of Human Plasma
    TREVOR CASTOR; Fiscal Year: 2009
    ..inactivation utilizing hydrolyzable compounds such as 2- proprionolactone and ozone;and photochemical decontamination using synthetic psoralens...
  6. A New Low Power Low Cost Ozone Sterilizer for Medical Equipment
    Joseph R Stetter; Fiscal Year: 2012
    ..is significant since the instrument will serve as a miniature, low power and low cost platform capable of decontamination of viral pathogens such as HIV, Hepatitis B and Hepatitis C (HBV, HCV)...
  7. College of Medicine Phoenix Campus Vivarium Phase I Construction
    William M Crist; Fiscal Year: 2010
    ..Specialized suites are included for behavioral analyses, ABSL2 containment and decontamination, and small animal imaging and irradiation...
  8. A fully integrated assay and platform for detecting Clostridium difficile
    BRUCE D IRVINE; Fiscal Year: 2010
    ..Most cases of remission are due to re-infection. Decontamination is very difficult and currently not supported by a reliable and sensitive method of verification...
  9. A New Point of Use Decontamination Method for Fresh Produce
    ADRIAN J DENVIR; Fiscal Year: 2010
    ..Higher microbial reductions on fresh produce could be achieved by using a gaseous decontamination that uses a sanitizing agent of greater lethality to contact and kill microorganisms that survive the ..
  10. Chlorite dismutase: a novel heme enzyme and its implications for human health
    Jennifer L Dubois; Fiscal Year: 2013
    ..g., for wound healing or water decontamination)...
  11. Epicenters III: Translational Research to Prevent Healthcare Associated Infection
    Richard Platt; Fiscal Year: 2013
    ..with complications of ventilator care: 3) We will explore the potential utility of chlorhexidine for gastric decontamination to reduce the incidence of ventilator-associated pneumonia and other nosocomial infections without selecting ..
  12. A Randomized Clinical Trial to Prevent Recurrent CA-MRASA Infection
    Loren Miller; Fiscal Year: 2009
    ..Others suggest environmental decontamination to help control recurrences and transmission within households...
  13. Evaluation of a Pulsed-Xenon Ultraviolet Room Disinfection Device
    John Zeber; Fiscal Year: 2013
    ..VA facilities, this implementation study will determine the clinical and economic benefits of a powerful new decontamination technology, since hand cleaning of discharged patient rooms requires substantial time, labor and supply costs...
  14. Compact Hydrogen Peroxide Sensor for Sterilization Cycle Monitoring
    Krishnan Parameswaran; Fiscal Year: 2013
    ..instrument with a large dynamic range and high sensitivity for monitoring VPHP during barrier isolator decontamination would be invaluable to manufacturers to improve product sterility assurance and quality...
  15. An environmental disinfection intervention to control Clostridium difficile
    CURTIS DONSKEY; Fiscal Year: 2013
    ..e., high-touch surfaces only cleaned if soiled) of CDI rooms versus standard cleaning plus daily decontamination of high-touch surfaces. The primary outcome measure will be healthcare worker hand contamination. and 3)...
  16. E-Learning Assisted HAZWOPER Training for Medicolegal Death Investigators
    JAMES PATRICK O'BRIEN; Fiscal Year: 2013
    ..training using training manikins, personal protective equipment, hazardous materials monitoring devices and decontamination equipment typical of a hazardous materials response...
  17. RUTGERS-UMDNJ BIOTECHNOLOGY TRAINING PROGRAM
    Martin L Yarmush; Fiscal Year: 2013
    ..use and industrial enzymes that cut chemical waste and energy consumption in manufacturing;as well as therapeutics, diagnostics, rapid response systems and decontamination enzymes aimed at neutralizing the agents of biological warfare.
  18. Novel Organophosphorous Hydrolases for Decontamination
    Andrew Mesecar; Fiscal Year: 2007
    ..the focus of intense research efforts aimed at developing these enzymes into products for enzyme- based decontamination. Unfortunately, the enzymes currently in development lack many of the desired properties such as solution ..
  19. Wound Decontamination for the Prevention and Treatment of Multi-drug Resistant Ba
    SHENDA BAKER; Fiscal Year: 2010
    ..Our aims focus on the characterization and development of a non-toxic, efficacious wound decontamination rinse for prevention and treatment of multi-drug resistant wound infections...
  20. Movable Equipment for DDB Animal Facility
    MARVIN MICHAEL SWINDLE; Fiscal Year: 2010
    ..Maintaining an SPF environment and remaining in compliance with current and future standards of laboratory animal care and use demand the highest achievable standards of disinfection, decontamination and occupational safety.
  21. Data Mining Assisted Discovery of Novel Organophosphorou
    Robert Turner; Fiscal Year: 2005
    ..become the focus of intense research efforts aimed at developing these enzymes into products for enzyme-based decontamination. However, currently available enzymes lack many of the desired properties such as solution solubility, ..
  22. Novel Organophosphorous Hydrolases for Decontamination
    Andrew Mesecar; Fiscal Year: 2004
    ..become the focus of intense research efforts aimed at developing these enzymes into products for enzyme-based decontamination. However, these enzymes lack many of the desired properties such as solution solubility, thermal and pH ..
  23. Develop and Test an Online Biohazard Simulator to Train Skilled Support Personnel
    MARGARET ANDREWS RUSH; Fiscal Year: 2011
    ..and applicable diseases, engineering and work practice controls, personal protective equipment and barriers, decontamination and disposal procedures, and post-exposure protocols...
  24. SURGERY AND IV NUTRITION MODULATE MACROPHAGE FUNCTION
    W Helton; Fiscal Year: 1999
    ..several mechanisms of TPN-induced stress a d macrophage dysfunction and include: oral antibiotic gut decontamination, intravenous polymixin B, partial duodenal nutrition, ingestion of a non digestible non-nutritious meal, ..
  25. ERADICATING BIOFILMS WITH AN ATMOSPHERIC GLOW PLASMA
    Kimberly Kelly Wintenberg; Fiscal Year: 2000
    ..PROPOSED COMMERCIAL APPLICATION: The OAUGDP technology is a new sterilization/decontamination process...
  26. PHOTOCHEMICAL DECONTAMINATION OF PLATELET CONCENTRATES
    Laurence Corash; Fiscal Year: 1993
    ..A photochemical decontamination(PCD) technique has been developed utilizing 8-methoxypsoralen (8-MOP) and long wavelength ultraviolet ..
  27. UMass BSL-3 Renovation
    JOHN LEWIS SULLIVAN; Fiscal Year: 2010
    ..system renovations to the 6th and 8th floors and roof level will accommodate a new Biokill kill tank effluent decontamination system, mechanical controls, and a prefabricated mechanical unit, dedicated to serving the new BSL-3 ..
  28. STERILIZING MEDICAL DEVICES WITH ATMOSPHERIC PLASMA
    Kimberly Kelly Wintenberg; Fiscal Year: 2001
    ..PROPOSED COMMERCIAL APPLICATION: The OAUGDP technology is a new sterilization/decontamination process...
  29. Nisin as a decontaminant for B. anthracis spores on human skin
    Kenneth Alibek; Fiscal Year: 2007
    ..Many of the decontamination regimens under investigation are too harsh for use on skin...
  30. HAZMAT Training at DOE Nuclear Weapons Complex
    JOHN J LECONCHE; Fiscal Year: 2013
    ..engaged in activities related to hazardous materials and waste generation, removal (including demolition and decontamination projects), containment, and emergency response within DOE facilities...
  31. High Throughput Bioengineering of Detoxification Enzymes
    Margaret Bradley; Fiscal Year: 2003
    ..optimal conditions of assay and other substrates (by us or by collaborators), and iii) finally adding adaptors and modifications to these enzymes for use as biosensors or as a detoxification and/or decontamination tools.
  32. Low Temp Decontamination/Sterilize/Dental Handpieces
    Mohamed Labib; Fiscal Year: 2005
    ..This development is expected to reduce DH costs for the dental practice, standardize DH cleaning and lubrication steps, and decrease exposure of dental workers to microbial contamination compared to the current practice. ..
  33. Point Source Ozonation to Minimize Antibiotic Resistance
    SCOTT OSBORN; Fiscal Year: 2009
    ..Phase II objectives are: " Objective 1: Compare cost and efficacy of the HYDOZ to standard disinfection/decontamination technology (BlueInGreen)...
  34. Hazmat Training at DOE Nuclear Weapons Complex Cooperative Agreement
    BARBARA ANN MCCABE; Fiscal Year: 2013
    ..community;empowering them to work safely conducting hazardous waste operations, facility decommissioning and decontamination, environmental restoration of contaminated facilities and chemical/radiological emergency response at the DOE ..
  35. HAIR ANALYSIS TO MONITOR DRUG ABUSE TREATMENTS
    Diana Wilkins; Fiscal Year: 2001
    ..Also, specific and selective decontamination procedures will be developed to minimize the potential bias of environmental contamination of hair for drugs ..
  36. DECONTAMINATION /STERILIZATION OF DENTAL HANDPIECES
    Mohamed Labib; Fiscal Year: 2000
    ..2. Application of technology to DUWL's and other dental tools. 3. Extrapolation of technology to other cleaning processes used in medical and industrial areas. ..
  37. CONTAINMENT FACILITIES FOR ANIMAL HOUSING AND RESEARCH
    MICHAEL DINGERSON; Fiscal Year: 1992
    ..b) a Class II biohazard containment hood for research procedures in rodents; and c) two autoclaves for decontamination of bedding, caging, and other housing materials, and for sterilization/decontamination of animal procedure ..
  38. DECONTAMINATION AND TREATMENT OF RED BAG WASTE
    Craig Andrews; Fiscal Year: 2000
    ..In the Phase I project, a pilot scale on-site treatment unit with a capacity to treat several hundred pounds of medical waste per day will be developed and evaluated. PROPOSED COMMERCIAL APPLICATION: NOT AVAILABLE ..
  39. HAZMAT Training at DOE Nuclear Weapons Complex
    ERICH J STAFFORD; Fiscal Year: 2013
    ..in this proposed training consortium, perform a vast array in hazardous waste operations, decommissioning and decontamination, transportation, restoration and emergency response activities...
  40. Field use of biocatalytic polymers for pesticide decon
    KEITH LEJEUNE; Fiscal Year: 2003
    ..The products envisioned to address the market needs consist of decontamination sponges and flow through devices...
  41. COMBINED EFFECT OF RADIATION & ASBESTOS IN PRODUCING PUL
    TIMOTHY TAKARO; Fiscal Year: 2001
    ..Workers may encounter asbestos fibers during building decontamination and demolition and be concomitantly exposed to radiation...
  42. Mobile Training of Skilled Support Personnel
    CESAR BANDERA; Fiscal Year: 2006
    ..learning modules on their cell phones about the hazardous agent(s) involved, the PPE needed and general decontamination procedures for the hazardous agent(s)...
  43. Novel Polymer Coatings for Prevention of Biofilms in Dental Unit Waterlines
    Jeffrey Dalsin; Fiscal Year: 2009
    ..approaches to Dental waterline antifouling that would significantly reduce or eliminate the need for routine decontamination maintenance are of great interest to the Dental healthcare community...
  44. Improving Institutional Animal Resources at MUSC
    MARVIN SWINDLE; Fiscal Year: 2006
    ..The hydrogen peroxide vapor biodecontamination unit is a high-level replacement for chemical decontamination with such agents as a paracetic acid; it is an upgrade in technology designed to ensure a uniformly effective ..
  45. Communicore Animal Facility (CAF) Renovation Phase III Part II
    AUGUST BATTLES; Fiscal Year: 2007
    ..will be reconfigured to provide an exit for potentially infectious caging and materials and their efficient decontamination. Additionally, the route of sterile caging into the ABSL3 from the new CAF Annex cage wash will be shortened ..
  46. Biotech Center Barrier Improvement Project
    Joseph Newsome; Fiscal Year: 2009
    ..Install a new vaporized hydrogen peroxide misting tunnel for decontamination of material to be moved into the barrier facility;and 3...
  47. EVALUATION OF SAFETY DATA REPORTING IN RANDOMIZED TRIALS
    Joseph Lau; Fiscal Year: 1999
    ..sinusitis, non-steroidal agents for rheumatoid arthritis, treatment for Helicobacter pylori, and selective decontamination of the gastrointestinal tract in the intensive care setting...
  48. Fixed Equipment for DDB Animal Resource
    MARVIN SWINDLE; Fiscal Year: 2009
    ..future standards of laboratory animal care and use demand the highest achievable standards of disinfection, decontamination and occupational safety...
  49. Photodynamic Blood Product Decontamination
    J Wharton; Fiscal Year: 2005
    ..system will be evaluated in a series of in vitro experiments to determine the optimal blood product decontamination applications of the new system...
  50. Polymer Coatings for Prevention of Bacterial Contamination of Dental Waterlines
    Jeffrey Dalsin; Fiscal Year: 2006
    ..approaches to dental waterline antifouling that would significantly reduce or eliminate the need for routine decontamination maintenance are of great interest to the dental healthcare community...
  51. PATHOPHYSIOLOGICAL BIOCHEMICAL CHANGES OF THERMAL INJURY
    Fiemu Nwariaku; Fiscal Year: 2009
    ..providing one proximal signal that triggers postburn innate host response;effects of selective decontamination of the digestive tract on postburn responses to subsequent sepsis (IT Streptococcus or Klebsiella pneumoniae) ..
  52. VIRUS INACTIVATION OF HUMAN RED CELLS FOR TRANSFUSION
    CLARK EDSON; Fiscal Year: 1999
    ..An effective virus decontamination procedure would address an enormous unmet need and represent a significant market opportunity...
  53. VALIDATION TEST FOR PATHOGEN INACTIVATION USING THE PCR
    Lily Lin; Fiscal Year: 1993
    The long-term goal is to develop photochemical decontamination (PCD) methods for the inactivation of infectious pathogens in blood products...
  54. VIRALLY INACTIVATED HUMAN RED CELLS FOR TRANSFUSION
    Andrei Purmal; Fiscal Year: 2004
    ..Thus, an effective virus decontamination procedure would address a significant unmet health need...
  55. Integrated Immunoassay/PCR Test for Bioterrorism Agents
    Cha Mei Tang; Fiscal Year: 2004
    ..Because it confirms organism viability, the test will enable real time monitoring of decontamination efforts, such as that recently performed at Washington DC postal facilities and government offices.
  56. Nanoparticle Coating System for Biomedical Applications
    Wenping Jiang; Fiscal Year: 2007
    ..In addition, the system has potential for coatings for drug delivery, environmental decontamination, and protective clothing. [unreadable] [unreadable] [unreadable]
  57. Point Source Ozonation to Minimize Antibiotic Resistance
    CLAY THOMPSON; Fiscal Year: 2005
    ..coli) in a model hospital wastewater effluent pipe when compared to existing decontamination technology (chlorination and macro-bubble ozonation)...
  58. SPORE PEPTIDOGLYCAN DEGRADATION IN BACILLUS ANTHRACIS
    DAVID POPHAM; Fiscal Year: 2005
    ..or treatments that activate cortex lysis, resulting in germination and rendering the spores susceptible to standard bactericidal agents, will allow easier decontamination of spore-contaminated sites and prevention of human exposure.
  59. Assay and Instrument Development for Diagnosis of Prion Disease
    Peixuan Zhu; Fiscal Year: 2007
    ..PrPSc are extraordinarily resistant to classic medical decontamination procedures...
  60. VALIDATION TEST FOR PATHOGEN INACTIVATION USING THE PCR
    Lily Lin; Fiscal Year: 1991
    ..A photochemical decontamination (PCD) procedure has been described which utilizes 8-methoxypsoralen (8-MOP) and long wavelength ultraviolet (..
  61. BIOCIDAL POLYMERS FOR DENTAL WATER CONTAMINATION CONTROL
    Jeffrey Williams; Fiscal Year: 1999
    ..Application to the control of air quality is also possible, depending on the configuration of the decontamination pathway devised to incorporate the antimicrobial polymers.
  62. A NEW APPROACH TO MICROBIAL DECONTAMINATION OF FOOD
    Thomas Rogers; Fiscal Year: 2001
    ..The project will conclude with manufacture and in-plant demonstration of a pilot scale germicidal rinse on chilled beef during full-scale production operations. PROPOSED COMMERCIAL APPLICATION: NOT AVAILABLE ..