decontamination

Summary

Summary: The removal of contaminating material, such as radioactive materials, biological materials, or CHEMICAL WARFARE AGENTS, from a person or object.

Top Publications

  1. ncbi Decontamination of surgical instruments from prions. II. In vivo findings with a model system for testing the removal of scrapie infectivity from steel surfaces
    Karin Lemmer
    P24, Transmissible Spongiform Encephalopathies, Robert Koch Institut, Nordufer 20, 13353 Berlin, Germany
    J Gen Virol 89:348-58. 2008
  2. pmc Evaluation of an automated ultraviolet radiation device for decontamination of Clostridium difficile and other healthcare-associated pathogens in hospital rooms
    Michelle M Nerandzic
    Research Service, Louis Stokes Cleveland Veterans Affairs Medical Center, 10701 East Boulevard, Cleveland, Ohio, USA
    BMC Infect Dis 10:197. 2010
  3. ncbi Changing bacterial ecology during a five-year period of selective intestinal decontamination
    W Lingnau
    Department of Anaesthesia and Intensive Care Medicine, Leopold Franzens University of Innsbruck, Austria
    J Hosp Infect 39:195-206. 1998
  4. ncbi Tackling contamination of the hospital environment by methicillin-resistant Staphylococcus aureus (MRSA): a comparison between conventional terminal cleaning and hydrogen peroxide vapour decontamination
    G L French
    Department of Infection, King s College London, North Wing, St Thomas Hospital, UK
    J Hosp Infect 57:31-7. 2004
  5. ncbi Impact of hydrogen peroxide vapor room decontamination on Clostridium difficile environmental contamination and transmission in a healthcare setting
    John M Boyce
    Hospital of St Raphael, Yale University School of Medicine, New Haven, Connecticut 06511, USA
    Infect Control Hosp Epidemiol 29:723-9. 2008
  6. doi Decontamination of the digestive tract and oropharynx in ICU patients
    A M G A de Smet
    Division of Perioperative and Emergency Care, University Medical Center, Utrecht, The Netherlands
    N Engl J Med 360:20-31. 2009
  7. ncbi Selective digestive tract decontamination and selective oropharyngeal decontamination and antibiotic resistance in patients in intensive-care units: an open-label, clustered group-randomised, crossover study
    Anne Marie G A de Smet
    Division of Perioperative and Emergency Care, University Medical Centre Utrecht, Utrecht, The Netherlands
    Lancet Infect Dis 11:372-80. 2011
  8. doi Decontamination of prion protein (BSE301V) using a genetically engineered protease
    J Dickinson
    Health Protection Agency, Porton Down, Salisbury, UK
    J Hosp Infect 72:65-70. 2009
  9. ncbi Decontamination of rooms, medical equipment and ambulances using an aerosol of hydrogen peroxide disinfectant
    B M Andersen
    Department of Hospital Infection, Ulleval University Hospital, Oslo, Norway
    J Hosp Infect 62:149-55. 2006
  10. doi Effect of saliva contamination and decontamination on bovine enamel bond strength of four self-etching adhesives
    Qin Jiang
    No 1 Hospital Aff to Medical College, Zhejiang University, Stomatology, Hangzhou, Zhejiang, China
    Oper Dent 35:194-202. 2010

Detail Information

Publications257 found, 100 shown here

  1. ncbi Decontamination of surgical instruments from prions. II. In vivo findings with a model system for testing the removal of scrapie infectivity from steel surfaces
    Karin Lemmer
    P24, Transmissible Spongiform Encephalopathies, Robert Koch Institut, Nordufer 20, 13353 Berlin, Germany
    J Gen Virol 89:348-58. 2008
    ..causing transmissible spongiform encephalopathies (TSEs) to chemical or thermal inactivation requires special decontamination procedures in order to prevent accidental transmission of these pathogens by surgical instruments...
  2. pmc Evaluation of an automated ultraviolet radiation device for decontamination of Clostridium difficile and other healthcare-associated pathogens in hospital rooms
    Michelle M Nerandzic
    Research Service, Louis Stokes Cleveland Veterans Affairs Medical Center, 10701 East Boulevard, Cleveland, Ohio, USA
    BMC Infect Dis 10:197. 2010
    ..Environmental surfaces play an important role in transmission of healthcare-associated pathogens. There is a need for new disinfection methods that are effective against Clostridium difficile spores, but also safe, rapid, and automated...
  3. ncbi Changing bacterial ecology during a five-year period of selective intestinal decontamination
    W Lingnau
    Department of Anaesthesia and Intensive Care Medicine, Leopold Franzens University of Innsbruck, Austria
    J Hosp Infect 39:195-206. 1998
    The development of bacterial resistance during selective decontamination of the digestive tract (SDD) is controversial...
  4. ncbi Tackling contamination of the hospital environment by methicillin-resistant Staphylococcus aureus (MRSA): a comparison between conventional terminal cleaning and hydrogen peroxide vapour decontamination
    G L French
    Department of Infection, King s College London, North Wing, St Thomas Hospital, UK
    J Hosp Infect 57:31-7. 2004
    ..by MRSA, and compared the effectiveness of standard cleaning with a new method of hydrogen peroxide vapour decontamination. MRSA contamination, measured by surface swabbing was compared before and after terminal cleaning that ..
  5. ncbi Impact of hydrogen peroxide vapor room decontamination on Clostridium difficile environmental contamination and transmission in a healthcare setting
    John M Boyce
    Hospital of St Raphael, Yale University School of Medicine, New Haven, Connecticut 06511, USA
    Infect Control Hosp Epidemiol 29:723-9. 2008
    To determine whether hydrogen peroxide vapor (HPV) decontamination can reduce environmental contamination with and nosocomial transmission of Clostridium difficile.
  6. doi Decontamination of the digestive tract and oropharynx in ICU patients
    A M G A de Smet
    Division of Perioperative and Emergency Care, University Medical Center, Utrecht, The Netherlands
    N Engl J Med 360:20-31. 2009
    Selective digestive tract decontamination (SDD) and selective oropharyngeal decontamination (SOD) are infection-prevention measures used in the treatment of some patients in intensive care, but reported effects on patient outcome are ..
  7. ncbi Selective digestive tract decontamination and selective oropharyngeal decontamination and antibiotic resistance in patients in intensive-care units: an open-label, clustered group-randomised, crossover study
    Anne Marie G A de Smet
    Division of Perioperative and Emergency Care, University Medical Centre Utrecht, Utrecht, The Netherlands
    Lancet Infect Dis 11:372-80. 2011
    Previously, we assessed selective digestive tract decontamination (SDD) and selective oropharyngeal decontamination (SOD) on survival and prevention of bacteraemia in patients in intensive-care units...
  8. doi Decontamination of prion protein (BSE301V) using a genetically engineered protease
    J Dickinson
    Health Protection Agency, Porton Down, Salisbury, UK
    J Hosp Infect 72:65-70. 2009
    ..This study demonstrates the potential for thermostable proteases to be developed as effective inactivation processes for prion agents in healthcare management...
  9. ncbi Decontamination of rooms, medical equipment and ambulances using an aerosol of hydrogen peroxide disinfectant
    B M Andersen
    Department of Hospital Infection, Ulleval University Hospital, Oslo, Norway
    J Hosp Infect 62:149-55. 2006
    ..Gloster Sante Europe) providing a dry fume of 5% hydrogen peroxide (H(2)O(2)) disinfectant was tested for decontamination of rooms, ambulances and different types of medical equipment...
  10. doi Effect of saliva contamination and decontamination on bovine enamel bond strength of four self-etching adhesives
    Qin Jiang
    No 1 Hospital Aff to Medical College, Zhejiang University, Stomatology, Hangzhou, Zhejiang, China
    Oper Dent 35:194-202. 2010
    ..This study evaluated the effect of saliva contamination on the bovine enamel microtensile bond strengths (microTBS) of four self-etching adhesives...
  11. ncbi Effects of decontamination and implant surface characteristics on re-osseointegration following treatment of peri-implantitis
    Ates Parlar
    Department of Periodontology, Faculty of Dentistry, Gazi University, Ankara, Turkey
    Clin Oral Implants Res 20:391-9. 2009
    ..Although considerable bone fill may occur following treatment of peri-implantitis, re-osseointegration appears to be limited and unpredictable...
  12. pmc Biodegradation of ochratoxin a for food and feed decontamination
    Luís Abrunhosa
    IBB, Institute for Biotechnology, Bioengineering, Centro de Engenharia Biólogica, Universidade do Minho, Campus de Gualtar, Braga, Portugal
    Toxins (Basel) 2:1078-99. 2010
    ..A critical discussion about the technical applicability of these strategies is presented...
  13. doi Non-thermal plasma technologies: new tools for bio-decontamination
    M Moreau
    Laboratory of Cold Microbiology, UPRES EA 2123, University of Rouen, Evreux, France
    Biotechnol Adv 26:610-7. 2008
    Bacterial control and decontamination are crucial to industrial safety assessments. However, most recently developed materials are not compatible with standard heat sterilization treatments...
  14. pmc Effects of decontamination, DNA extraction, and amplification procedures on the molecular diagnosis of Mycobacterium ulcerans disease (Buruli ulcer)
    Dissou Affolabi
    Laboratoire de Référence des Mycobactéries, Cotonou, Benin
    J Clin Microbiol 50:1195-8. 2012
    ..All of these procedures were compared before and after decontamination. We observed that, among the procedures tested, real-time PCR after the modified Boom extraction method or a ..
  15. ncbi Surface decontamination of surgical instruments: an ongoing dilemma
    H Murdoch
    Centre for Emergency Preparedness and Response Laboratory A, Health Protection Agency, Porton Down, Salisbury, UK
    J Hosp Infect 63:432-8. 2006
    ....
  16. ncbi Comparison of different decontamination methods for reagents to detect low concentrations of bacterial 16S DNA by real-time-PCR
    Sven Klaschik
    Klinik und Poliklinik fur Anasthesiologie und spezielle Intensivmedizin, Universitat Bonn, Sigmund Freud Strasse 25, D 53105 Bonn, Germany
    Mol Biotechnol 22:231-42. 2002
    ..We have tested four different methods of decontamination of PCR reagents in a project aimed at detecting bacterial DNA at low concentrations: deoxyribonuclease (DNAse)..
  17. doi Randomized controlled trial and meta-analysis of oral decontamination with 2% chlorhexidine solution for the prevention of ventilator-associated pneumonia
    Hutsaya Tantipong
    Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand
    Infect Control Hosp Epidemiol 29:131-6. 2008
    To determine the effectiveness of oral decontamination with 2% chlorhexidine solution for the prevention of ventilator-associated pneumonia (VAP).
  18. ncbi Lethal photosensitization for decontamination of implant surfaces in the treatment of peri-implantitis
    O Dörtbudak
    Department of Oral Surgery, School of Dentistry of the University of Vienna, Vienna, Austria
    Clin Oral Implants Res 12:104-8. 2001
    ..The application of TBO and laser resulted in a significant reduction (P<0.0001) of the initial values in all 3 groups of bacteria. Complete elimination of bacteria was not achieved...
  19. ncbi Reagent decontamination to eliminate false-positives in Escherichia coli qPCR
    Sarah S Silkie
    Civil and Environmental Engineering Department, University of California, Berkeley, CA 94720 1710, USA
    J Microbiol Methods 72:275-82. 2008
    ..coli and other bacterial DNA. We optimized a DNase I decontamination method to eliminate false-positives in a qPCR assay targeting the uidA gene in E. coli...
  20. ncbi Comparison of NaOH-N-acetyl cysteine and sulfuric acid decontamination methods for recovery of mycobacteria from clinical specimens
    Patricia C A M Buijtels
    Medical Centre Rijnmond South, Location Clara, Department of Medical Microbiology, Olympiaweg 350, 3078 HT, Rotterdam, The Netherlands
    J Microbiol Methods 62:83-8. 2005
    We compared the NaOH-N-acetyl cysteine (NaOH-NALC) and the sulfuric acid decontamination procedure in the detection of mycobacteria using the Mycobacteria Growth Indicator Tube (MGIT)...
  21. ncbi Selective digestive decontamination: for everyone, everywhere?
    Jean Louis Vincent
    Department of Intensive Care, Erasme Hospital, Free University of Brussels, 1070, Brussels, Belgium
    Lancet 362:1006-7. 2003
  22. ncbi Organophosphate skin decontamination using immobilized enzymes
    R K Gordon
    Walter Reed Army Institute of Research, Division of Biochemistry, Washington, DC 20307, USA
    Chem Biol Interact 119:463-70. 1999
    ..the applicability of OP scavengers from in vivo protection, to a variety of external detoxification and decontamination schemes...
  23. doi Cutaneous challenge with chemical warfare agents in the SKH-1 hairless mouse. (I) Development of a model for screening studies in skin decontamination and protection
    F Dorandeu
    Département de toxicologie et risque chimique, Institut de Recherche Biomédicale des Armées, Centre de Recherches du Service de Sante des Armees, La Tronche, France
    Hum Exp Toxicol 30:470-90. 2011
    ..Although efficient means of decontamination are available, most of them lose their efficacy when decontamination is delayed after exposure of the bare ..
  24. doi Gaseous and air decontamination technologies for Clostridium difficile in the healthcare environment
    A Davies
    Centre for Emergency Preparedness and Response, Health Protection Agency, Porton Down, Salisbury, Wiltshire, UK
    J Hosp Infect 77:199-203. 2011
    ..Alternative disinfection technologies such as gaseous decontamination are currently being marketed to the healthcare sector as an alternative/supplement to manual disinfection, ..
  25. doi Evaluation of decontamination process of heart valve and artery tissues in European Homograft Bank (EHB): a retrospective study of 1,055 cases
    Ye Dong Fan
    European Homograft Bank EHB, International Association, c o Military Hospital Queen Astrid, Brussels, Belgium
    Cell Tissue Bank 13:297-304. 2012
    To evaluate the efficiency of decontamination practice in European Homograft Bank (EHB), the data of the cardiovascular tissues received during recent 2 years were retrospectively analysed in this study...
  26. doi Prevention of ventilator-associated pneumonia by selective decontamination of the digestive tract
    L Silvestri
    Eur Respir J 32:241-3. 2008
  27. doi Active surveillance testing and decontamination strategies in intensive care units to reduce methicillin-resistant Staphylococcus aureus infections
    Asok Kurup
    Department of Infectious Diseases, Singapore General Hospital, Singapore
    Am J Infect Control 38:361-7. 2010
    Active surveillance testing (AST) and decontamination strategies (DS) using a topical methicillin-resistant Staphylococcus aureus (MRSA) cleansing agent was introduced in July 2007 in a medical intensive care unit (MICU) and a surgical ..
  28. ncbi Assessing the biological efficacy and rate of recontamination following hydrogen peroxide vapour decontamination
    J A Otter
    BIOQUELL UK Ltd, Andover, Hampshire, UK
    J Hosp Infect 67:182-8. 2007
    ..Hydrogen peroxide vapour (HPV) decontamination has proven effective for the eradication of persistent environmental contamination...
  29. doi Immobilization of Russian VX skin depots by localized cooling: implications for decontamination and medical countermeasures
    J Mikler
    Defence Research and Development Canada Suffield, Box 4000, Medicine Hat, Alberta, Canada T1A8K6
    Toxicol Lett 206:47-53. 2011
    ..b>Decontamination with the Reactive Skin Decontaminant Lotion (RSDL) 15 min after VR exposure was completely effective in ..
  30. ncbi [Hygiene and methods of decontamination, disinfection and sterilization in dental offices in Yaounde]
    J Onana
    Service d odonto stomatologie, Hôpital Militaire de Yaoundé, BP 1162 Yaoundé, Cameroun
    Odontostomatol Trop 25:45-51. 2002
    ..The ways of cleaning, decontamination, disinfection or of sterilization of the premises, the dental equipment and instruments, hand-washing, ..
  31. pmc Chemical, physical and biological approaches to prevent ochratoxin induced toxicoses in humans and animals
    Janos Varga
    Department of Microbiology, Faculty of Science and Informatics, University of Szeged, Közép fasor 52, H 6726 Szeged, Hungary
    Toxins (Basel) 2:1718-50. 2010
    ..These strategies can be classified into three main categories: prevention of ochratoxin contamination, decontamination or detoxification of foods contaminated with ochratoxins, and inhibition of the absorption of consumed ..
  32. ncbi Decontamination of pork carcasses during scalding and the prevention of Salmonella cross-contamination
    D J Bolton
    The National Food Centre, Ashtown, Dublin 15, Republic of Ireland
    J Appl Microbiol 94:1036-42. 2003
    ..The objective of this study was to establish critical temperature limits to prevent cross-contamination of pork carcasses during scalding...
  33. ncbi Comparative analysis of showering protocols for mass-casualty decontamination
    Richard Amlot
    Health Protection Agency, Salisbury, Wiltshire, UK
    Prehosp Disaster Med 25:435-9. 2010
    A well-established provision for mass-casualty decontamination that incorporates the use of mobile showering units has been developed in the UK...
  34. ncbi In vitro evaluation of different chemical agents for the decontamination of gutta-percha cones
    Rogério Emílio de Souza
    School of Dentistry, University of Ribeirao Preto
    Pesqui Odontol Bras 17:75-7. 2003
    This study evaluated the effectiveness of three disinfectants used in Dentistry for decontamination of gutta-percha cones...
  35. ncbi The challenge of prion decontamination
    Gerald McDonnell
    Steris, Basingstoke, Hampshire, United Kingdom
    Clin Infect Dis 36:1152-4. 2003
  36. doi Evaluation of the decontamination efficacy of new and reprocessed microfiber cleaning cloth compared with other commonly used cleaning cloths in the hospital
    Magda Diab-Elschahawi
    Clinical Institute for Hygiene and Medical Microbiology, Division for Hospital Hygiene, Vienna General Hospital, Medical University of Vienna, Waehringer Guertel 18 20, Vienna, Austria
    Am J Infect Control 38:289-92. 2010
    The aim of this study was to investigate the decontamination capacity of 4 different types of cleaning cloths (microfiber cleaning cloth, cotton cloth, sponge cloth, and disposable paper towels) commonly used in hospital in their ability ..
  37. pmc An efficient strategy for broad-range detection of low abundance bacteria without DNA decontamination of PCR reagents
    Shy Shin Chang
    Graduate Institute of Clinical Medical Sciences, Department of Medicine, College of Medicine, Chang Gung University, Tao Yuan, Taiwan, Republic of China
    PLoS ONE 6:e20303. 2011
    ..Although several DNA decontamination protocols have been reported, they all suffer from compromised PCR efficiency or detection limits...
  38. ncbi Truth hurts--hard lessons from Australia's largest mass casualty exercise with contaminated patients
    Nicholas A Edwards
    Intensive Care Unit, Royal Adelaide Hospital, Adelaide, South Australia, Australia
    Emerg Med Australas 18:185-95. 2006
    ..by the exercise, which we believe have enormous implications for the development of hospital chemical, biological or radiological plans and the likelihood of their success--hospital security, crowd control and decontamination.
  39. ncbi Processing of cardiovascular allografts: effectiveness of European Homograft Bank (EHB) antimicrobial treatment (cool decontamination protocol with low concentration of antibiotics)
    M Tabaku
    European Homograft Bank, International Association, Brussels, Belgium
    Cell Tissue Bank 5:261-6. 2004
    To assess the effectiveness of antimicrobial treatment by using cool decontamination protocol with low concentration of antibiotics during processing of cardiovascular allografts, 948 allografts processed during a 2-year period were ..
  40. doi Influence of decontamination procedures on shear forces after contamination with blood or saliva
    Lorenz Brauchli
    Clinic of Orthodontics and Pedodontics, University of Basel, Basel, Switzerland
    Am J Orthod Dentofacial Orthop 138:435-41. 2010
    ..The aims of this study were to evaluate the influence of contamination on bond strength and to investigate possible decontamination procedures.
  41. ncbi Public experiences of mass casualty decontamination
    Holly Carter
    Emergency Response Department, Health Protection Agency, Salisbury, United Kingdom
    Biosecur Bioterror 10:280-9. 2012
    In this article, we analyze feedback from simulated casualties who took part in field exercises involving mass decontamination, to gain an understanding of how responder communication can affect people's experiences of and compliance ..
  42. ncbi Decontamination of grains and legumes infected with Aspergillus spp. and Penicillum spp. by cold plasma treatment
    Meral Selcuk
    Department of Food Engineering, Suleyman Demirel University, Isparta, Turkey
    Bioresour Technol 99:5104-9. 2008
    ..and Penicillum spp. artificially contaminated on seed surface. The plasma decontamination process was performed by batch process in vacuum chamber, using gas injection followed by plasma discharge ..
  43. ncbi Long-term use of selective decontamination of the digestive tract does not increase antibiotic resistance: a 5-year prospective cohort study
    María E Ochoa-Ardila
    Intensive Care Unit, Fundación Valle del Lilli, Cali, Colombia
    Intensive Care Med 37:1458-65. 2011
    Despite the evidence, the use of selective decontamination of the digestive tract (SDD) remains controversial, largely because of concerns that it may promote the emergence of antibiotic-resistant strains...
  44. doi Response surface methodology-based optimization of decontamination conditions for Escherichia coli O157:H7 and Salmonella Typhimurium on fresh-cut celery using thermoultrasound and calcium propionate
    Tae Yeon Kwak
    Division of Food Bioscience and Technology, Korea University, Seoul, 136 713, South Korea
    Int J Food Microbiol 150:128-35. 2011
    ..coli O157:H7 and S. Typhimurium on fresh-cut celery. Furthermore, this treatment extends fresh storability without physical quality deterioration...
  45. ncbi A laboratory evaluation of the decontamination properties of microfibre cloths
    G Moore
    School of Applied Sciences, University of Wales Institute, Cardiff, UK
    J Hosp Infect 64:379-85. 2006
    ..Different makes of microfibre cloths have different characteristics, and the name 'microfibre' should not imply superior cleaning efficacy...
  46. ncbi Emergence of multidrug-resistant Gram-negative bacteria during selective decontamination of the digestive tract on an intensive care unit
    Nashwan Al Naiemi
    Academic Medical Center, Department of Medical Microbiology Amsterdam, The Netherlands
    J Antimicrob Chemother 58:853-6. 2006
    During treatment with selective decontamination of the digestive tract (SDD), four multidrug-resistant (MDR) strains, three different Escherichia coli and one Klebsiella pneumoniae, were isolated from four patients not known as carriers ..
  47. doi Effect of contamination and decontamination on adhesion of a resin-modified glass-ionomer cement to bovine dentin
    Pitsapaporn Wangpermtam
    Department of Oral Rehabilitation, The University of Hong Kong, Hong Kong
    J Adhes Dent 13:445-53. 2011
    ..To determine the adhesion of resin-modified glass-ionomer cement to bovine dentin under contaminated and decontaminated conditions...
  48. pmc Evaluation of a hand-held far-ultraviolet radiation device for decontamination of Clostridium difficile and other healthcare-associated pathogens
    Michelle M Nerandzic
    Research Service, Louis Stokes Cleveland Veterans Affairs Medical Center, Cleveland, OH, USA
    BMC Infect Dis 12:120. 2012
    ..The Sterilray™ Disinfection Wand device is a hand-held room decontamination technology that utilizes far-ultraviolet radiation (185-230 nm) to kill pathogens.
  49. ncbi Decontamination of deep dentin by means of erbium, chromium:yttrium-scandium-gallium-garnet laser irradiation
    Rene Franzen
    Department for Conservative Dentistry, Periodontology and Preventive Dentistry ZPP, RWTH Aachen University, Aachen, Germany
    Lasers Med Sci 24:75-80. 2009
    ..05). Scanning electron microscopy (SEM) micrographs of the contaminated and irradiated surfaces showed the absence of a smear layer and opened dentinal tubules...
  50. ncbi Room decontamination with UV radiation
    William A Rutala
    Hospital Epidemiology, University of North Carolina Health Care, and the Division of Infectious Diseases, University of North Carolina School of Medicine, Chapel Hill, NC 27599 7030, USA
    Infect Control Hosp Epidemiol 31:1025-9. 2010
    ..To determine the effectiveness of a UV-C-emitting device to eliminate clinically important nosocomial pathogens in a contaminated hospital room...
  51. ncbi Weapons of mass destruction events with contaminated casualties: effective planning for health care facilities
    A G Macintyre
    Department of Emergency Medicine, George Washington University Medical Center, Washington, DC, USA
    JAMA 283:242-9. 2000
    ..HCF response plan include prompt recognition of the incident, staff and facility protection, patient decontamination and triage, medical therapy, and coordination with external emergency response and public health agencies...
  52. ncbi Microbial contamination of toothbrushes and their decontamination
    P Nelson Filho
    Department of Pediatric Dentistry, School of Dentistry of Ribeirao Preto, University of Sao Paulo, Brazil
    Pediatr Dent 22:381-4. 2000
    ....
  53. ncbi Bacterial contamination and decontamination of toothbrushes after use
    Abhishek Mehta
    Department of Community Dentistry, Jaipur Dental College, India
    N Y State Dent J 73:20-2. 2007
    ..Overnight immersion of a toothbrush in chlorhexidine gluconate (0.2%) was found to be highly effective in preventing such microbial contamination...
  54. pmc Hypothermia does not increase the risk of infection: a case control study
    Marlijn Kamps
    Department of Intensive Care, Radboud University Nijmegen Medical Centre PO Box 9101, 6500 HB Nijmegen, The Netherlands
    Crit Care 15:R48. 2011
    ..Prolonged hypothermic treatment may further enhance the risk of infection. Selective decontamination of the digestive tract (SDD) reduces the risk of respiratory tract infections...
  55. doi Application of a novel decontamination process using gaseous ozone
    John Moat
    University of Manchester School of Medicine, Manchester Royal Infirmary, UK
    Can J Microbiol 55:928-33. 2009
    ..Recently, there has been interest in the use of vapor- and gas-based treatments for decontamination of surfaces and rooms...
  56. pmc Impact of digestive and oropharyngeal decontamination on the intestinal microbiota in ICU patients
    Robin F Benus
    Department of Medical Microbiology, University Medical Centre Groningen, University of Groningen, Groningen, The Netherlands
    Intensive Care Med 36:1394-402. 2010
    Selective digestive microbial decontamination (SDD) is hypothesized to benefit patients in intensive care (ICU) by suppressing Gram-negative potential pathogens from the colon without affecting the anaerobic intestinal microbiota...
  57. ncbi PCNA-expression of cementoblasts and fibroblasts on the root surface after extraoral rinsing for decontamination
    Ulrike Ebensberger
    Department of Oral Surgery, University of Bonn, Bonn, Germany
    Dent Traumatol 18:262-6. 2002
    ..24). Ozonized water, not being isotonic, had no negative effect on periodontal cells remaining on the tooth surface after irrigation for 2 min...
  58. ncbi Analysis of hydrofluoric acid penetration and decontamination of the eye by means of time-resolved optical coherence tomography
    Felix Spöler
    Institute of Semiconductor Electronics, RWTH Aachen University, Sommerfeldstrasse 24, 52074 Aachen, Germany
    Burns 34:549-55. 2008
    So far the study of chemical burns has lacked techniques to define penetration kinetics and the effects of decontamination within biological structures...
  59. ncbi An improved method for emergent decontamination of ocular and dermal hydrofluoric acid splashes
    Kjell Soderberg
    Medical Service, Avesta Polarit, Torshalla, Sweden
    Vet Hum Toxicol 46:216-8. 2004
    ..This report describes the utilization of Hexafluorine--a hypertonic, amphoteric, chelating decontamination solution--in workplaces where water decontamination followed by calcium gluconate inunction failed to prevent ..
  60. ncbi Hydrogen peroxide vapour decontamination in an overcrowded tertiary care referral centre: some practical answers
    J A Otter
    J Hosp Infect 62:384-5. 2006
  61. pmc Improved laboratory safety by decontamination of unstained sputum smears for acid-fast microscopy
    Luiz Roberto Bigão Giacomelli
    Departamento de Analises Clinicas, Universidade Estadual de Maringa, PR, Brazil
    J Clin Microbiol 43:4245-8. 2005
    ..7% for 1 min (tube technique) or for 10 min (slide technique) were effective in decontaminating sputum smears and preserved cell morphology and quantitative acid-fast microscopy results...
  62. ncbi Cleanability of dental instruments--implications of residual protein and risks from Creutzfeldt-Jakob disease
    J T Walker
    HPA Centre for Emergency Preparedness and Response, Porton Down, Salisbury, SP4 0JG
    Br Dent J 203:395-401. 2007
    ....
  63. ncbi Pulsed-light system as a novel food decontamination technology: a review
    N Elmnasser
    Laboratoire d Analyse, de Traitement et de Valorisation des Polluants de l Environnement et de Produits Faculte de Pharmacie de Monastir, Rue Avicenne, 5000 Monastir, Tunisie
    Can J Microbiol 53:813-21. 2007
    ..It appears to constitute a good alternative or a complement to conventional thermal or chemical decontamination processes...
  64. ncbi Point-of-care controls for nosocomial legionellosis combined with chlorine dioxide potable water decontamination: a two-year survey at a Welsh teaching hospital
    I K Hosein
    Infection Prevention and Control Department, Cardiff and Vale NHS Trust, University Hospital of Wales, Heath Park, Cardiff CF14 4XW, Wales, UK
    J Hosp Infect 61:100-6. 2005
    ....
  65. pmc Oral decontamination with chlorhexidine reduces the incidence of nosocomial pneumonia
    Ilias I Siempos
    Crit Care 11:402; author reply 402. 2007
  66. ncbi Investigations of a prion infectivity assay to evaluate methods of decontamination
    Guillaume Fichet
    STERIS Laboratory, CEA DSV IMETI SEPIA, Fontenay aux Roses, France
    J Microbiol Methods 70:511-8. 2007
    ..and various industrial surfaces, but there is currently no standard, accepted model to evaluate surface prion decontamination. In this report, a set of both in vitro and in vivo methods were investigated based on the contamination of ..
  67. ncbi Microbial contamination of tooth brushes and their decontamination
    S S Bhat
    Department of Pedodontics and Preventive Dentistry, Yenepoya Dental College, Mangalore, Karnataka
    J Indian Soc Pedod Prev Dent 21:108-12. 2003
    ..Disappearance of growth of microorganisms was seen in Gp I and Gp II and remnants of growth seen in Gp III. It can be concluded that the use of disinfectant is a must for every individual at regular intervals...
  68. ncbi Selective decontamination of digestive tract in intensive care
    Henri A Verbrugh
    Lancet 362:2117-8. 2003
  69. doi Bone microbial decontamination agents in osseous grafting: an in vitro study with fresh human explants
    Fernando Verdugo
    VA Hospital, Greater Los Angeles, Healthcare System, Los Angeles, CA, USA
    J Periodontol 82:863-71. 2011
    ..Establishing a safe prophylactic antimicrobial protocol in bone grafting may enhance osseous volume outcomes. The purpose of this in vitro study is to assess human osteoblast response and safety after explant antimicrobial exposure...
  70. pmc Development of a test system to evaluate procedures for decontamination of respirators containing viral droplets
    Evanly Vo
    National Institute for Occupational Safety and Health, National Personal Protective Technology Laboratory, Pittsburgh, PA 15236, USA
    Appl Environ Microbiol 75:7303-9. 2009
    The aim of this study was to develop a test system to evaluate the effectiveness of procedures for decontamination of respirators contaminated with viral droplets. MS2 coliphage was used as a surrogate for pathogenic viruses...
  71. pmc A standardized comparison of commercially available prion decontamination reagents using the Standard Steel-Binding Assay
    Julie Ann Edgeworth
    MRC Prion Unit, Department of Neurodegenerative Disease, UCL Institute of Neurology, Queen Square, London WC1N 3BG, UK
    J Gen Virol 92:718-26. 2011
    ..transfer infectivity to a suitable host, and much research has been performed to achieve effective prion decontamination of metal surfaces...
  72. doi [Caustic injuries of the eye, skin and the gastrointestinal tract]
    Florian Eyer
    Toxikologische Abteilung der II Medizinischen Klinik, Klinikum rechts der Isar Technische Universität München, Munchen
    Ther Umsch 66:379-86. 2009
    ..All chemical exposures to the eye require immediate decontamination by copious irrigation with an aqueous solution for at least 15-30 minutes up to two hours in single cases of ..
  73. pmc Evaluation of five decontamination methods for filtering facepiece respirators
    Dennis J Viscusi
    National Institute for Occupational Safety and Health, National Personal Protective Technology Laboratory, Pittsburgh, PA 15236, USA
    Ann Occup Hyg 53:815-27. 2009
    ..One possible strategy to mitigate a respirator shortage is to reuse FFRs following a biological decontamination process to render infectious material on the FFR inactive...
  74. ncbi Efficient decontamination of zearalenone, the mycotoxin of cereal pathogen, by transgenic yeasts through the expression of a synthetic lactonohydrolase gene
    Naoko Takahashi-Ando
    Laboratory for Remediation Research, Plant Science Center, RIKEN, 1 7 22 Suehiro, Tsurumi, Yokohama, Kanagawa, 230 0045, Japan
    Appl Microbiol Biotechnol 67:838-44. 2005
    ..The result suggests that incomplete ZEN detoxification attributed to the action of an endogenous yeast beta-reductase can be overcome by simply increasing the expression of the detoxifying gene...
  75. ncbi Alteromonas prolidase for organophosphorus G-agent decontamination
    T C Cheng
    Environmental Technology Team, US Army Edgewood Research, Development and Engineering Center, Aberdeen, MD 21010, USA
    Chem Biol Interact 119:455-62. 1999
    ..sp.JD6.5 with the goal of developing strategies for long-term storage and decontamination have been successfully achieved...
  76. ncbi Comparison of two concentrations of NALC-NaOH for decontamination of sputum for mycobacterial culture
    R L Peres
    Nucleo de Doencas Infecciosas, Universidade Federal do Espirito Santo, Vitoria, Espirito Santo, Brazil
    Int J Tuberc Lung Dis 13:1572-5. 2009
    ..of sodium hydroxide (NaOH) in the N-acetyl-L-cysteine-sodium hydroxide (NALC-NaOH) method for sputum decontamination on smear and culture positivity and the proportion of contaminated cultures: 14% of cultures were ..
  77. doi Colonic sterilization for natural orifice translumenal endoscopic surgery (NOTES) procedures: a comparison of two decontamination protocols
    Sharon L Bachman
    Department of Surgery, University of Missouri, One Hospital Drive, Columbia, MO 65212, USA
    Surg Endosc 23:1854-9. 2009
    ..This study aimed to evaluate the effect of two different sterilization protocols on the bacterial counts in the swine colon as preparation for natural orifice translumenal endoscopic surgery (NOTES) surgery...
  78. doi A method to determine the available UV-C dose for the decontamination of filtering facepiece respirators
    E M Fisher
    National Institute for Occupational Safety and Health, National Personal Protective, Technology Laboratory, Pittsburgh, PA 15236, USA
    J Appl Microbiol 110:287-95. 2011
    To develop a method to assess model-specific parameters for ultraviolet-C (UV-C, 254 nm) decontamination of filtering facepiece respirators (FFRs).
  79. ncbi Decontamination of polymerase chain reaction reagents using DEAE-cellulose
    S A Glushkov
    Institute of Cytology and Genetics, Siberian Branch of Russian Academy of Sciences, Novosibirsk 630090, Russian Federation
    Anal Biochem 393:135-7. 2009
    ..from contaminating nucleic acid using DEAE-cellulose and present the analysis of this technique for both decontamination efficiency and an effect on the reagent activity...
  80. ncbi Infectivity of prion protein bound to stainless steel wires: a model for testing decontamination procedures for transmissible spongiform encephalopathies
    Zheng Xin Yan
    SMP GmbH Pruefen Validieren Forschen, Tubingen, Germany
    Infect Control Hosp Epidemiol 25:280-3. 2004
    ..and steel wires contaminated with infectious brain materials as transfer vehicles, and, based on this model, to test decontamination procedures against the infectious prion proteins on the steel wires as a near real situation bioassay.
  81. ncbi The role of selective decontamination of the digestive tract in acute stroke
    M Gosney
    The Institute of Health Sciences, Building 22, London Road, Reading RG1 5AQ, UK
    Age Ageing 35:42-7. 2006
    ..following a stroke, morbidity and mortality is high, with aspiration pneumonia being a common complication...
  82. doi A pandemic influenza preparedness study: use of energetic methods to decontaminate filtering facepiece respirators contaminated with H1N1 aerosols and droplets
    Brian K Heimbuch
    Applied Research Associates, Tyndall Air Force Base, 104 Research Road, Panama City, FL 32403, USA
    Am J Infect Control 39:e1-9. 2011
    ..The focus of this research effort was on evaluating the ability of microwave-generated steam, warm moist heat, and ultraviolet germicidal irradiation at 254 nm to decontaminate H1N1 influenza virus...
  83. ncbi Water decontamination of chemical skin/eye splashes: a critical review
    Alan H Hall
    Toxicology Consulting and Medical Translating Services, Elk Mountain, Wyoming 82324, USA
    Cutan Ocul Toxicol 25:67-83. 2006
    Skin/eye chemical splashes are a significant workplace problem. Initial water decontamination is usually recommended, but there are few well-conducted experimental animal and human studies of efficacy...
  84. pmc Development of a test system to apply virus-containing particles to filtering facepiece respirators for the evaluation of decontamination procedures
    Edward Fisher
    EG and G Technical Services, Inc, Pittsburgh, Pennsylvania 15236, USA
    Appl Environ Microbiol 75:1500-7. 2009
    ..substrates (coupons) was constructed and validated as part of a method to assess the virucidal efficacy of decontamination procedures for filtering facepiece respirators...
  85. pmc Probiotics versus antibiotic decontamination of the digestive tract: infection and mortality
    Guy J Oudhuis
    Department of Medical Microbiology, NUTRIM School for Nutrition, Toxicology and Metabolism, Maastricht University Medical Centre, PO Box 5800, 6202 AZ Maastricht, The Netherlands
    Intensive Care Med 37:110-7. 2011
    Selective decontamination of the digestive tract (SDD) has been shown to decrease the infection rate and mortality in intensive care units (ICUs); Lactobacillus plantarum 299/299v plus fibre (LAB) has been used for infection prevention ..
  86. pmc Tuberculosis diagnosis and multidrug resistance testing by direct sputum culture in selective broth without decontamination or centrifugation
    Louis Grandjean
    Departamento de Microbiologia, Facultad de Ciencias, Laboratorios de Investigación y Desarrollo, Universidad Peruana Cayetano Heredia, Lima, Peru
    J Clin Microbiol 46:2339-44. 2008
    Tuberculosis culture usually requires sputum decontamination and centrifugation to prevent cultures from being overgrown by contaminating bacteria and fungi...
  87. ncbi Analysis of residual chemicals on filtering facepiece respirators after decontamination
    W B Salter
    Applied Research Associates, Tyndall Air Force Base, Florida 32403, USA
    J Occup Environ Hyg 7:437-45. 2010
    ..be established, many parameters affecting respiratory protection must be measured: biocidal efficacy of the decontamination treatment, filtration performance, pressure drop, fit, and toxicity to the end user post treatment...
  88. ncbi Intralaboratory reproducibility of the German test method of prEN ISO 15883-1 for determination of the cleaning efficacy of washer-disinfectors for flexible endoscopes
    B Zühlsdorf
    Technische Hygiene, Charite Universitatsmedizin Berlin, Campus Benjamin Franklin, Hindenburgdamm 27, 12203 Berlin, Germany
    J Hosp Infect 59:286-91. 2005
    ..2 (range: 1.6-3.2) and excellent visible cleanliness of the test pieces. We found that the prEN ISO 15883-1 German test method leads to reproducible and valid results, and is suitable for determining the cleaning efficacy in WDs...
  89. ncbi Biodegradation of ochratoxin A by Aspergillus section Nigri species isolated from French grapes: a potential means of ochratoxin A decontamination in grape juices and musts
    Hend Bejaoui
    Laboratoire de Génie Chimique UMR5503 CNRS INPT UPS, Département Bioprocédés et Systèmes Microbiens ENSAT INPT 1, Auzeville Tolozane, Castanet Tolosan, France
    FEMS Microbiol Lett 255:203-8. 2006
    ..After 9 days of incubation, OTalpha had decreased, whereas an unknown compound appeared. A. niger could be the first interesting species for OTA detoxification processes, followed by A. japonicus...
  90. ncbi Decontamination of multiple casualties who are chemically contaminated: a challenge for acute hospitals
    Simon F J Clarke
    Emergency Department, Frimley Park NHS Foundation Trust, Portsmouth Road, Frimley, Camberley, Surrey GU16 7UJ, UK
    Prehosp Disaster Med 23:175-81. 2008
    ..The risks and potential consequences of this gap in resilience are discussed and a number of possible practical solutions are proposed...
  91. ncbi The effect of multiple cycles of contamination, detergent washing, and disinfection on the development of biofilm in endoscope tubing
    Karen Vickery
    Department of Plastic and Reconstructive Surgery, Liverpool Hospital and Surgical Infection Research Group, South Western Clinical School, University of New South Wales, Sydney, Australia
    Am J Infect Control 37:470-5. 2009
    ..Biofilm bacteria are firmly attached to one another and to the substrate by exopolysaccharide, making them difficult to remove. We analyzed the effect of 20 wash/contamination cycles on biofilm formation...
  92. doi Survival benefit of the full selective digestive decontamination regimen
    Luciano Silvestri
    Unit of Anesthesia and Intensive Care, Department of Emergency, Presidio Ospedaliero di Gorizia, 34170 Gorizia, Italy
    J Crit Care 24:474.e7-14. 2009
    We assessed the impact of the full protocol of selective decontamination of the digestive tract (SDD) using parenteral and enteral antimicrobials on mortality.
  93. ncbi Effect of prion decontamination protocols on nickel-titanium rotary surfaces
    David Sonntag
    Department of Operative Dentistry, Philipps Universitat Marburg, Georg Voigt Strasse 3, 35033 Marburg, Germany
    J Endod 33:442-6. 2007
    b>Decontamination of instruments is a prerequisite for their potential reuse but may affect surface integrity. Hence, the effect of prion removal protocols on 7 brands of nickel-titanium files was investigated...
  94. ncbi Decontamination of orthodontic bands following size determination and cleaning
    P E Benson
    Department of Oral Health and Development, Institution School of Clinical Dentistry, Claremont Crescent, Sheffield, S10 2TA, UK
    J Orthod 34:18-24. 2007
    ..To measure the effectiveness of ultrasonic cleaning for decontaminating orthodontic molar bands following size determination using a quantitative antibody capture assay technique...
  95. ncbi Selective decontamination of the digestive tract reduces bacterial bloodstream infection and mortality in critically ill patients. Systematic review of randomized, controlled trials
    L Silvestri
    Department of Anaesthesia and Intensive Care, Presidio Ospedaliero, Gorizia, Italy
    J Hosp Infect 65:187-203. 2007
    A systematic review and meta-analysis of randomized controlled trials (RCTs) of selective decontamination of the digestive tract (SDD) was undertaken to evaluate the impact of this procedure on bacterial bloodstream infection and ..
  96. doi Gastrointestinal decontamination of the poisoned patient
    Spencer Greene
    Department of Emergency Medicine, Wright State University Boonshoft School of Medicine, Dayton, OH 45429, USA
    Pediatr Emerg Care 24:176-86; quiz 187-9. 2008
    Gastrointestinal decontamination has been a historically accepted modality in the emergency management of oral intoxicants...
  97. doi Decontamination of chemical and biological warfare agents with a single multi-functional material
    Gabi Amitai
    McGowan Institute for Regenerative Medicine, University of Pittsburgh, 450 Technology Drive, Pittsburgh, PA 15219, USA
    Biomaterials 31:4417-25. 2010
    ..dimethylacrylamide-methacrylate (DMAA-MA) co-polymer backbone that support both chemical and biological agent decontamination. Polyurethanes containing the redox enzymes glucose oxidase and horseradish peroxidase can convert halide ..
  98. ncbi Selective decontamination of the digestive tract: cumulating evidence, at last?
    Marc J M Bonten
    Department of Internal Medicine, Division of General Medicine, Infectious Diseases and Geriatrics, Eijkman Winkler Institute for Microbiology, Inflammation and Infectious Diseases, University Medical Centre Utrecht, The Netherlands
    Semin Respir Crit Care Med 27:18-22. 2006
    Selective decontamination of the digestive tract (SDD), an infection-control strategy designed to prevent nosocomial pneumonia in mechanically ventilated patients, has been implemented in numerous studies for more than 2 decades, but its ..
  99. ncbi Chemical and biological weapons. Implications for anaesthesia and intensive care
    S M White
    Department of Anaesthesia, Guy s and St Thomas Hospital Trust, St Thomas Street, London SE1 9RT, UK
    Br J Anaesth 89:306-24. 2002
    ..The specific roles of the anaesthetist and intensivist in treatment are highlighted...
  100. ncbi Potential agents of chemical warfare. Worst-case scenario protection and decontamination methods
    Angeline A Lazarus
    Department of Internal Medicine, National Naval Medical Center, 8901 Wisconsin Ave, Bethesda, MD 20889 5600, USA
    Postgrad Med 112:133-40. 2002
  101. ncbi Relationship between methodological trial quality and the effects of selective digestive decontamination on pneumonia and mortality in critically ill patients
    C A van Nieuwenhoven
    Department of Internal Medicine, Division of Infectious Diseases and AIDS, University Hospital, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands
    JAMA 286:335-40. 2001
    Although meta-analyses of randomized trials have shown that selective digestive decontamination (SDD) prevents nosocomial pneumonia in critically ill patients, the influence of trial quality on the effectiveness of SDD has not been ..

Research Grants76

  1. Processing of Materials for Improved Biocompatibility
    Michael Matthews; Fiscal Year: 2004
    ..used in biomedical devices such as prostheses and implants by providing a higher level of cleanliness and decontamination, while simultaneously providing sterilization...
  2. CFI Inactivation of Human Plasma
    TREVOR CASTOR; Fiscal Year: 2009
    ..inactivation utilizing hydrolyzable compounds such as 2- proprionolactone and ozone;and photochemical decontamination using synthetic psoralens...
  3. Nonheme Diiron Centers/Biological Oxidation Hydrocarbons
    STEPHEN LIPPARD; Fiscal Year: 2006
    ..of the molecular mechanisms of O2 activation and substrate hydroxylation provided by this research will advance novel strategies for environmental decontamination and the development of catalysts to convert methane to methanol.
  4. Nonheme Diiron Centers and the Biological Oxidation of Hydrocarbons
    STEPHEN LIPPARD; Fiscal Year: 2007
    ..of the molecular mechanisms of O2 activation and substrate hydroxylation provided by this research will advance novel strategies for environmental decontamination and the development of catalysts to convert methane to methanol.
  5. Nonheme Diiron Centers and the Biological Oxidation of Hydrocarbons
    STEPHEN LIPPARD; Fiscal Year: 2009
    ..of the molecular mechanisms of O2 activation and substrate hydroxylation provided by this research will advance novel strategies for environmental decontamination and the development of catalysts to convert methane to methanol.
  6. Nonheme Diiron Centers and the Biological Oxidation of Hydrocarbons
    STEPHEN LIPPARD; Fiscal Year: 2009
    ..of the molecular mechanisms of O2 activation and substrate hydroxylation provided by this research will advance novel strategies for environmental decontamination and the development of catalysts to convert methane to methanol.
  7. Durable Visible Light-activated Antivral Coatings for Fabrics Used for Personal P
    JOSEF STEPHAN SCHNEIDER; Fiscal Year: 2010
    ..Thus, opportunities exist for simple, efficacious decontamination methods that reduce the risk of infection through handling a contaminated respirator and that do not ..
  8. A New Point of Use Decontamination Method for Fresh Produce
    ADRIAN J DENVIR; Fiscal Year: 2010
    ..Higher microbial reductions on fresh produce could be achieved by using a gaseous decontamination that uses a sanitizing agent of greater lethality to contact and kill microorganisms that survive the ..
  9. Nonheme Diiron Centers and the Biological Oxidation of Hydrocarbons
    STEPHEN LIPPARD; Fiscal Year: 2007
    ..molecular mechanisms of 62 activation and substrate hydroxylation provided by this research will advance novel strategies for environmental decontamination and the development of catalysts to convert methane to methanol.
  10. Novel Organophosphorous Hydrolases for Decontamination
    Andrew Mesecar; Fiscal Year: 2006
    ..the focus of intense research efforts aimed at developing these enzymes into products for enzyme- based decontamination. Unfortunately, the enzymes currently in development lack many of the desired properties such as solution ..
  11. Novel Organophosphorous Hydrolases for Decontamination
    Andrew Mesecar; Fiscal Year: 2007
    ..the focus of intense research efforts aimed at developing these enzymes into products for enzyme- based decontamination. Unfortunately, the enzymes currently in development lack many of the desired properties such as solution ..
  12. Testing Interventions to Human-Generated Occupational Airborne Infections
    Edward Nardell; Fiscal Year: 2009
    ..We will test both a conventional HEPA filter unit and novel low-maintenance electrostatic air decontamination technology developed for use in outer space...
  13. Testing Interventions to Human-Generated Occupational Airborne Infections
    Edward A Nardell; Fiscal Year: 2010
    ..We will test both a conventional HEPA filter unit and novel low-maintenance electrostatic air decontamination technology developed for use in outer space...
  14. Testing Interventions to Human-Generated Occupational Airborne Infections
    Edward Nardell; Fiscal Year: 2007
    ..We will test both a conventional HEPA filter unit and novel low-maintenance electrostatic air decontamination technology developed for use in outer space...
  15. Testing Interventions to Human-Generated Occupational Airborne Infections
    Edward A Nardell; Fiscal Year: 2010
    ..We will test both a conventional HEPA filter unit and novel low-maintenance electrostatic air decontamination technology developed for use in outer space...
  16. Testing Interventions to Human-Generated Occupational Airborne Infections
    Edward Nardell; Fiscal Year: 2006
    ..We will test both a conventional HEPA filter unit and novel low-maintenance electrostatic air decontamination technology developed for use in outer space...
  17. Processing of Materials for Improved Biocompatibility
    Michael Matthews; Fiscal Year: 2004
    ..used in biomedical devices such as prostheses and implants by providing a higher level of cleanliness and decontamination, while simultaneously providing sterilization...
  18. Processing of Materials for Improved Biocompatibility
    Michael Matthews; Fiscal Year: 2002
    ..used in biomedical devices such as prostheses and implants by providing a higher level of cleanliness and decontamination, while simultaneously providing sterilization...
  19. Processing of Materials for Improved Biocompatibility
    Michael Matthews; Fiscal Year: 2003
    ..used in biomedical devices such as prostheses and implants by providing a higher level of cleanliness and decontamination, while simultaneously providing sterilization...
  20. An environmental disinfection intervention to control Clostridium difficile
    CURTIS DONSKEY; Fiscal Year: 2011
    ..e., high-touch surfaces only cleaned if soiled) of CDI rooms versus standard cleaning plus daily decontamination of high-touch surfaces. The primary outcome measure will be healthcare worker hand contamination. and 3)...
  21. A New Low Power Low Cost Ozone Sterilizer for Medical Equipment
    Joseph R Stetter; Fiscal Year: 2012
    ..is significant since the instrument will serve as a miniature, low power and low cost platform capable of decontamination of viral pathogens such as HIV, Hepatitis B and Hepatitis C (HBV, HCV)...
  22. Nonheme Diiron Centers and the Biological Oxidation of Hydrocarbons
    Stephen J Lippard; Fiscal Year: 2010
    ..The ability of these hydrocarbon-consuming "superbugs" to degrade chlorinated hydrocarbons has led to their application in the bioremediation of industrial wastewater, decontamination of seawater, and removal of soil pollutants.
  23. Data Mining Assisted Discovery of Novel Organophosphorou
    Robert Turner; Fiscal Year: 2005
    ..become the focus of intense research efforts aimed at developing these enzymes into products for enzyme-based decontamination. However, currently available enzymes lack many of the desired properties such as solution solubility, ..
  24. Novel Organophosphorous Hydrolases for Decontamination
    Andrew Mesecar; Fiscal Year: 2004
    ..become the focus of intense research efforts aimed at developing these enzymes into products for enzyme-based decontamination. However, these enzymes lack many of the desired properties such as solution solubility, thermal and pH ..
  25. SURGERY AND IV NUTRITION MODULATE MACROPHAGE FUNCTION
    W Helton; Fiscal Year: 1999
    ..several mechanisms of TPN-induced stress a d macrophage dysfunction and include: oral antibiotic gut decontamination, intravenous polymixin B, partial duodenal nutrition, ingestion of a non digestible non-nutritious meal, ..
  26. College of Medicine Phoenix Campus Vivarium Phase I Construction
    William M Crist; Fiscal Year: 2010
    ..Specialized suites are included for behavioral analyses, ABSL2 containment and decontamination, and small animal imaging and irradiation...
  27. A fully integrated assay and platform for detecting Clostridium difficile
    BRUCE D IRVINE; Fiscal Year: 2010
    ..Most cases of remission are due to re-infection. Decontamination is very difficult and currently not supported by a reliable and sensitive method of verification...
  28. A fully integrated assay and platform for detecting Clostridium difficile
    Bruce Irvine; Fiscal Year: 2009
    ..Most cases of remission are due to re-infection. Decontamination is very difficult and currently not supported by a reliable and sensitive method of verification...
  29. ERADICATING BIOFILMS WITH AN ATMOSPHERIC GLOW PLASMA
    Kimberly Kelly Wintenberg; Fiscal Year: 2000
    ..PROPOSED COMMERCIAL APPLICATION: The OAUGDP technology is a new sterilization/decontamination process...
  30. ORAL CARE INTERVENTION IN MECHANICALLY VENTILATED ADULTS
    Cindy L Munro; Fiscal Year: 2010
    ..Pre-intubation oral decontamination could reduce risk of VAP and its associated morbidity and mortality...
  31. ORAL CARE INTERVENTION IN MECHANICALLY VENTILATED ADULTS
    Cindy Munro; Fiscal Year: 2009
    ..Pre-intubation oral decontamination could reduce risk of VAP and its associated morbidity and mortality...
  32. Proteomic Analyses of Clostridium difficile Spore Germination Apparatus
    DAVID L contact POPHAM; Fiscal Year: 2010
    ..These "superdormant" spores are resistant to decontamination and are a potential cause of infection at later dates...
  33. PHOTOCHEMICAL DECONTAMINATION OF PLATELET CONCENTRATES
    Laurence Corash; Fiscal Year: 1993
    ..A photochemical decontamination(PCD) technique has been developed utilizing 8-methoxypsoralen (8-MOP) and long wavelength ultraviolet ..
  34. PHOTOCHEMICAL DECONTAMINATION OF PLATELET CONCENTRATES
    Laurence Corash; Fiscal Year: 1991
    ..A photochemical decontamination(PCD) technique has been developed utilizing 8-methoxypsoralen (8-MOP) and long wavelength ultraviolet ..
  35. A Novel Approach to Assessing Cognitive State During Real-World Tasks
    Robin Johnson; Fiscal Year: 2011
    ..We propose to advance the portable, wireless EEG system, the B-Alert(R) X10 to accommodate these limitations, by adaptation of both the artifact decontamination and cognitive state (engagement and workload) algorithms.
  36. Novel antioxidant therapeutics for sulfur mustard toxicity (U54)
    Carl White; Fiscal Year: 2006
    ..There are no specific treatments or antidotes for HD nor preventive medications to minimize its effects. Decontamination and supportive care are the only interventions recommended by current medical guidelines and more of these ..
  37. Novel antioxidant therapeutics for sulfur mustard toxicity (U54)
    Carl White; Fiscal Year: 2009
    ..There are no specific treatments or antidotes for HD nor preventive medications to minimize its effects. Decontamination and supportive care are the only interventions recommended by current medical guidelines and more of these ..
  38. Novel antioxidant therapeutics for sulfur mustard toxicity (U54)
    Carl White; Fiscal Year: 2009
    ..There are no specific treatments or antidotes for HD nor preventive medications to minimize its effects. Decontamination and supportive care are the only interventions recommended by current medical guidelines and more of these ..
  39. Novel antioxidant therapeutics for sulfur mustard toxicity (U54)
    Carl White; Fiscal Year: 2007
    ..There are no specific treatments or antidotes for HD nor preventive medications to minimize its effects. Decontamination and supportive care are the only interventions recommended by current medical guidelines and more of these ..
  40. BACTERIAL MEDIATION OF GUT FUNCTION IN POSTINJURY ILEUS
    FRANK MOODY; Fiscal Year: 1999
    ..Therapeutic strategies to include bacterial decontamination, enteral nutrition, carboxypeptidase perfusion, and pro-kinetic motor stimulation will be evaluated in the ..
  41. STERILIZING MEDICAL DEVICES WITH ATMOSPHERIC PLASMA
    Kimberly Kelly Wintenberg; Fiscal Year: 2001
    ..PROPOSED COMMERCIAL APPLICATION: The OAUGDP technology is a new sterilization/decontamination process...
  42. Emergency Preparedness for Special Populations
    David Markenson; Fiscal Year: 2004
    ..health emergency preparedness, children with special healthcare needs and technologically assisted children, decontamination of children, biological terrorism prophylaxis and treatment of emerging agents, and family-centered ..
  43. Emergency Preparedness for Special Populations
    David Markenson; Fiscal Year: 2005
    ..health emergency preparedness, children with special healthcare needs and technologically assisted children, decontamination of children, biological terrorism prophylaxis and treatment of emerging agents, and family-centered ..
  44. Nisin as a decontaminant for B. anthracis spores on human skin
    Kenneth Alibek; Fiscal Year: 2006
    ..Many of the decontamination regimens under investigation are too harsh for use on skin...
  45. Nisin as a decontaminant for B. anthracis spores on human skin
    Kenneth Alibek; Fiscal Year: 2007
    ..Many of the decontamination regimens under investigation are too harsh for use on skin...
  46. Compact Hydrogen Peroxide Sensor for Sterilization Cycle Monitoring
    Krishnan Parameswaran; Fiscal Year: 2012
    ..instrument with a large dynamic range and high sensitivity for monitoring VPHP during barrier isolator decontamination would be invaluable to manufacturers to improve product sterility assurance and quality...
  47. Public Health Prevention Fund (PPHF) Ventilator Associated Pneumonia ACA
    MICHAEL contact KLOMPAS; Fiscal Year: 2011
    ..with complications of ventilator care: 3) We will explore the potential utility of chlorhexidine for gastric decontamination to reduce the incidence of ventilator-associated pneumonia and other nosocomial infections without selecting ..
  48. Novel diagnostics and therapeutics for caliciviruses
    MARY ESTES; Fiscal Year: 2007
    ..contaminated, eradication of infectious virus is difficult and expensive, and effective methods of evaluating decontamination remain unclear due in part to the inability to propagate the virus in cultured cells or animal models...
  49. SPORE PEPTIDOGLYCAN SYNTHESIS IN BACILLUS SUBTILIS
    DAVID POPHAM; Fiscal Year: 2002
    ..Knowledge of principles of endospore resistance properties, dormancy,and longevity may contribute to better decontamination methods and methods for storage and transport of drugs and vaccines...
  50. SPORE PEPTIDOGLYCAN SYNTHESIS IN BACILLUS SUBTILIS
    DAVID POPHAM; Fiscal Year: 2000
    ..Knowledge of principles of endospore resistance properties, dormancy,and longevity may contribute to better decontamination methods and methods for storage and transport of drugs and vaccines...
  51. SPORE PEPTIDOGLYCAN SYNTHESIS IN BACILLUS SUBTILIS
    DAVID POPHAM; Fiscal Year: 1999
    ..Knowledge of principles of endospore resistance properties, dormancy,and longevity may contribute to better decontamination methods and methods for storage and transport of drugs and vaccines...
  52. High Throughput Bioengineering of Detoxification Enzymes
    Margaret Bradley; Fiscal Year: 2003
    ..optimal conditions of assay and other substrates (by us or by collaborators), and iii) finally adding adaptors and modifications to these enzymes for use as biosensors or as a detoxification and/or decontamination tools.
  53. Point Source Ozonation to Minimize Antibiotic Resistance
    SCOTT OSBORN; Fiscal Year: 2009
    ..Phase II objectives are: " Objective 1: Compare cost and efficacy of the HYDOZ to standard disinfection/decontamination technology (BlueInGreen)...
  54. Novel diagnostics and therapeutics for caliciviruses
    MARY ESTES; Fiscal Year: 2004
    ..contaminated, eradication of infectious virus is difficult and expensive, and effective methods of evaluating decontamination remain unclear due in part to the inability to propagate the virus in cultured cells or animal models...
  55. Novel diagnostics and therapeutics for caliciviruses
    MARY ESTES; Fiscal Year: 2006
    ..contaminated, eradication of infectious virus is difficult and expensive, and effective methods of evaluating decontamination remain unclear due in part to the inability to propagate the virus in cultured cells or animal models...
  56. Novel diagnostics and therapeutics for caliciviruses
    MARY ESTES; Fiscal Year: 2005
    ..contaminated, eradication of infectious virus is difficult and expensive, and effective methods of evaluating decontamination remain unclear due in part to the inability to propagate the virus in cultured cells or animal models...
  57. SPORE PEPTIDOGLYCAN SYNTHESIS IN BACILLUS SUBTILIS
    DAVID POPHAM; Fiscal Year: 2001
    ..Knowledge of principles of endospore resistance properties, dormancy,and longevity may contribute to better decontamination methods and methods for storage and transport of drugs and vaccines...
  58. MECHANISMS OF SUCCESSFUL ADOPTIVE IMMUNOTHERAPY
    ROBERT TRUITT; Fiscal Year: 1980
    ..The unique feature of the treatment model is the use of intestinal decontamination and isolation in a protective environment to prevent secondary disease...
  59. Biofilm Formation by Listeria monocytogenes
    KATHERINE LEMON; Fiscal Year: 2006
    ..This makes decontamination of biofilm-coated surfaces particularly difficult...
  60. Low Temp Decontamination/Sterilize/Dental Handpieces
    Mohamed Labib; Fiscal Year: 2005
    ..This development is expected to reduce DH costs for the dental practice, standardize DH cleaning and lubrication steps, and decrease exposure of dental workers to microbial contamination compared to the current practice. ..
  61. Low Temp Decontamination/Sterilize/Dental Handpieces
    Mohamed Labib; Fiscal Year: 2004
    ..This development is expected to reduce DH costs for the dental practice, standardize DH cleaning and lubrication steps, and decrease exposure of dental workers to microbial contamination compared to the current practice. ..
  62. Biofilm Formation by Listeria monocytogenes
    KATHERINE LEMON; Fiscal Year: 2007
    ..This makes decontamination of biofilm-coated surfaces particularly difficult...
  63. A Randomized Clinical Trial to Prevent Recurrent CA-MRASA Infection
    Loren Miller; Fiscal Year: 2006
    ..Others suggest environmental decontamination to help control recurrences and transmission within households...
  64. A Randomized Clinical Trial to Prevent Recurrent CA-MRASA Infection
    Loren Miller; Fiscal Year: 2009
    ..Others suggest environmental decontamination to help control recurrences and transmission within households...
  65. A Randomized Clinical Trial to Prevent Recurrent CA-MRASA Infection
    Loren Miller; Fiscal Year: 2007
    ..Others suggest environmental decontamination to help control recurrences and transmission within households...
  66. Communicore Animal Facility (CAF) Renovation Phase III Part II
    AUGUST BATTLES; Fiscal Year: 2007
    ..will be reconfigured to provide an exit for potentially infectious caging and materials and their efficient decontamination. Additionally, the route of sterile caging into the ABSL3 from the new CAF Annex cage wash will be shortened ..
  67. CONTAINMENT FACILITIES FOR ANIMAL HOUSING AND RESEARCH
    MICHAEL DINGERSON; Fiscal Year: 1992
    ..b) a Class II biohazard containment hood for research procedures in rodents; and c) two autoclaves for decontamination of bedding, caging, and other housing materials, and for sterilization/decontamination of animal procedure ..
  68. HAIR ANALYSIS TO MONITOR DRUG ABUSE TREATMENTS
    Diana Wilkins; Fiscal Year: 2000
    ..Also, specific and selective decontamination procedures will be developed to minimize the potential bias of environmental contamination of hair for drugs ..
  69. Alcohol Intoxication and Postburn Intestinal Immunity
    Mashkoor Choudhry; Fiscal Year: 2009
    ..In Specific Aim 2 studies using approaches of selective decontamination of intestine with antibiotics prior to EtOH intoxication and burn injury will determine whether intestinal ..
  70. HAIR ANALYSIS TO MONITOR DRUG ABUSE TREATMENTS
    Diana Wilkins; Fiscal Year: 1999
    ..Also, specific and selective decontamination procedures will be developed to minimize the potential bias of environmental contamination of hair for drugs ..
  71. Alcohol Intoxication and Postburn Intestinal Immunity
    Mashkoor Choudhry; Fiscal Year: 2009
    ..In Specific Aim 2 studies using approaches of selective decontamination of intestine with antibiotics prior to EtOH intoxication and burn injury will determine whether intestinal ..
  72. Alcohol Intoxication and Postburn Intestinal Immunity
    Mashkoor Choudhry; Fiscal Year: 2007
    ..In Specific Aim 2 studies using approaches of selective decontamination of intestine with antibiotics prior to EtOH intoxication and burn injury will determine whether intestinal ..
  73. HAIR ANALYSIS TO MONITOR DRUG ABUSE TREATMENTS
    Diana Wilkins; Fiscal Year: 2001
    ..Also, specific and selective decontamination procedures will be developed to minimize the potential bias of environmental contamination of hair for drugs ..
  74. Novel Polymer Coatings for Prevention of Biofilms in Dental Unit Waterlines
    Jeffrey Dalsin; Fiscal Year: 2009
    ..approaches to Dental waterline antifouling that would significantly reduce or eliminate the need for routine decontamination maintenance are of great interest to the Dental healthcare community...