decontamination

Summary

Summary: The removal of contaminating material, such as radioactive materials, biological materials, or CHEMICAL WARFARE AGENTS, from a person or object.

Top Publications

  1. ncbi Decontamination of the digestive tract and oropharynx in ICU patients
    A M G A de Smet
    Division of Perioperative and Emergency Care, University Medical Center, Utrecht, The Netherlands
    N Engl J Med 360:20-31. 2009
  2. ncbi Decontamination of surgical instruments from prions. II. In vivo findings with a model system for testing the removal of scrapie infectivity from steel surfaces
    Karin Lemmer
    P24, Transmissible Spongiform Encephalopathies, Robert Koch Institut, Nordufer 20, 13353 Berlin, Germany
    J Gen Virol 89:348-58. 2008
  3. ncbi Changing bacterial ecology during a five-year period of selective intestinal decontamination
    W Lingnau
    Department of Anaesthesia and Intensive Care Medicine, Leopold Franzens University of Innsbruck, Austria
    J Hosp Infect 39:195-206. 1998
  4. ncbi Surface decontamination of surgical instruments: an ongoing dilemma
    H Murdoch
    Centre for Emergency Preparedness and Response (Laboratory A, Health Protection Agency, Porton Down, Salisbury, UK
    J Hosp Infect 63:432-8. 2006
  5. ncbi The role of selective decontamination of the digestive tract in acute stroke
    M Gosney
    The Institute of Health Sciences, Building 22, London Road, Reading RG1 5AQ, UK
    Age Ageing 35:42-7. 2006
  6. ncbi Randomized controlled trial and meta-analysis of oral decontamination with 2% chlorhexidine solution for the prevention of ventilator-associated pneumonia
    Hutsaya Tantipong
    Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand
    Infect Control Hosp Epidemiol 29:131-6. 2008
  7. ncbi Comparison of different decontamination methods for reagents to detect low concentrations of bacterial 16S DNA by real-time-PCR
    Sven Klaschik
    , , Sigmund Freud Strasse 25, D-53105 Bonn, Germany
    Mol Biotechnol 22:231-42. 2002
  8. ncbi Reagent decontamination to eliminate false-positives in Escherichia coli qPCR
    Sarah S Silkie
    Civil and Environmental Engineering Department, University of California, Berkeley, CA 94720 1710, USA
    J Microbiol Methods 72:275-82. 2008
  9. ncbi Comparison of NaOH-N-acetyl cysteine and sulfuric acid decontamination methods for recovery of mycobacteria from clinical specimens
    Patricia C A M Buijtels
    Medical Centre Rijnmond South, Location Clara, Department of Medical Microbiology, Olympiaweg 350, 3078 HT, Rotterdam, The Netherlands
    J Microbiol Methods 62:83-8. 2005
  10. ncbi Impact of digestive and oropharyngeal decontamination on the intestinal microbiota in ICU patients
    Robin F Benus
    Department of Medical Microbiology, University Medical Centre Groningen, University of Groningen, Groningen, The Netherlands
    Intensive Care Med 36:1394-402. 2010

Detail Information

Publications224 found, 100 shown here

  1. ncbi Decontamination of the digestive tract and oropharynx in ICU patients
    A M G A de Smet
    Division of Perioperative and Emergency Care, University Medical Center, Utrecht, The Netherlands
    N Engl J Med 360:20-31. 2009
    Selective digestive tract decontamination (SDD) and selective oropharyngeal decontamination (SOD) are infection-prevention measures used in the treatment of some patients in intensive care, but reported effects on patient outcome are ..
  2. ncbi Decontamination of surgical instruments from prions. II. In vivo findings with a model system for testing the removal of scrapie infectivity from steel surfaces
    Karin Lemmer
    P24, Transmissible Spongiform Encephalopathies, Robert Koch Institut, Nordufer 20, 13353 Berlin, Germany
    J Gen Virol 89:348-58. 2008
    ..causing transmissible spongiform encephalopathies (TSEs) to chemical or thermal inactivation requires special decontamination procedures in order to prevent accidental transmission of these pathogens by surgical instruments...
  3. ncbi Changing bacterial ecology during a five-year period of selective intestinal decontamination
    W Lingnau
    Department of Anaesthesia and Intensive Care Medicine, Leopold Franzens University of Innsbruck, Austria
    J Hosp Infect 39:195-206. 1998
    The development of bacterial resistance during selective decontamination of the digestive tract (SDD) is controversial...
  4. ncbi Surface decontamination of surgical instruments: an ongoing dilemma
    H Murdoch
    Centre for Emergency Preparedness and Response (Laboratory A, Health Protection Agency, Porton Down, Salisbury, UK
    J Hosp Infect 63:432-8. 2006
    ....
  5. ncbi The role of selective decontamination of the digestive tract in acute stroke
    M Gosney
    The Institute of Health Sciences, Building 22, London Road, Reading RG1 5AQ, UK
    Age Ageing 35:42-7. 2006
    ..following a stroke, morbidity and mortality is high, with aspiration pneumonia being a common complication...
  6. ncbi Randomized controlled trial and meta-analysis of oral decontamination with 2% chlorhexidine solution for the prevention of ventilator-associated pneumonia
    Hutsaya Tantipong
    Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand
    Infect Control Hosp Epidemiol 29:131-6. 2008
    To determine the effectiveness of oral decontamination with 2% chlorhexidine solution for the prevention of ventilator-associated pneumonia (VAP).
  7. ncbi Comparison of different decontamination methods for reagents to detect low concentrations of bacterial 16S DNA by real-time-PCR
    Sven Klaschik
    , , Sigmund Freud Strasse 25, D-53105 Bonn, Germany
    Mol Biotechnol 22:231-42. 2002
    ..We have tested four different methods of decontamination of PCR reagents in a project aimed at detecting bacterial DNA at low concentrations: deoxyribonuclease (DNAse)..
  8. ncbi Reagent decontamination to eliminate false-positives in Escherichia coli qPCR
    Sarah S Silkie
    Civil and Environmental Engineering Department, University of California, Berkeley, CA 94720 1710, USA
    J Microbiol Methods 72:275-82. 2008
    ..coli and other bacterial DNA. We optimized a DNase I decontamination method to eliminate false-positives in a qPCR assay targeting the uidA gene in E. coli...
  9. ncbi Comparison of NaOH-N-acetyl cysteine and sulfuric acid decontamination methods for recovery of mycobacteria from clinical specimens
    Patricia C A M Buijtels
    Medical Centre Rijnmond South, Location Clara, Department of Medical Microbiology, Olympiaweg 350, 3078 HT, Rotterdam, The Netherlands
    J Microbiol Methods 62:83-8. 2005
    We compared the NaOH-N-acetyl cysteine (NaOH-NALC) and the sulfuric acid decontamination procedure in the detection of mycobacteria using the Mycobacteria Growth Indicator Tube (MGIT)...
  10. ncbi Impact of digestive and oropharyngeal decontamination on the intestinal microbiota in ICU patients
    Robin F Benus
    Department of Medical Microbiology, University Medical Centre Groningen, University of Groningen, Groningen, The Netherlands
    Intensive Care Med 36:1394-402. 2010
    Selective digestive microbial decontamination (SDD) is hypothesized to benefit patients in intensive care (ICU) by suppressing Gram-negative potential pathogens from the colon without affecting the anaerobic intestinal microbiota...
  11. ncbi Application of a novel decontamination process using gaseous ozone
    John Moat
    University of Manchester School of Medicine, Manchester Royal Infirmary, UK
    Can J Microbiol 55:928-33. 2009
    ..Recently, there has been interest in the use of vapor- and gas-based treatments for decontamination of surfaces and rooms...
  12. ncbi Bacterial contamination and decontamination of toothbrushes after use
    Abhishek Mehta
    Department of Community Dentistry, Jaipur Dental College, India
    N Y State Dent J 73:20-2. 2007
    ..Overnight immersion of a toothbrush in chlorhexidine gluconate (0.2%) was found to be highly effective in preventing such microbial contamination...
  13. ncbi Effects of decontamination and implant surface characteristics on re-osseointegration following treatment of peri-implantitis
    Ates Parlar
    Department of Periodontology, Faculty of Dentistry, Gazi University, Ankara, Turkey
    Clin Oral Implants Res 20:391-9. 2009
    ..Objectives: To evaluate the effects of various decontamination techniques and implant surface configurations on re-osseointegration of contaminated dental implants.
  14. ncbi PCNA-expression of cementoblasts and fibroblasts on the root surface after extraoral rinsing for decontamination
    Ulrike Ebensberger
    Department of Oral Surgery, University of Bonn, Bonn, Germany
    Dent Traumatol 18:262-6. 2002
    ..24). Ozonized water, not being isotonic, had no negative effect on periodontal cells remaining on the tooth surface after irrigation for 2 min...
  15. ncbi Selective digestive tract decontamination and selective oropharyngeal decontamination and antibiotic resistance in patients in intensive-care units: an open-label, clustered group-randomised, crossover study
    Anne Marie G A de Smet
    Division of Perioperative and Emergency Care, University Medical Centre Utrecht, Utrecht, The Netherlands
    Lancet Infect Dis 11:372-80. 2011
    Previously, we assessed selective digestive tract decontamination (SDD) and selective oropharyngeal decontamination (SOD) on survival and prevention of bacteraemia in patients in intensive-care units...
  16. ncbi Weapons of mass destruction events with contaminated casualties: effective planning for health care facilities
    A G Macintyre
    Department of Emergency Medicine, George Washington University Medical Center, Washington, DC, USA
    JAMA 283:242-9. 2000
    ..HCF response plan include prompt recognition of the incident, staff and facility protection, patient decontamination and triage, medical therapy, and coordination with external emergency response and public health agencies...
  17. ncbi Hypothermia does not increase the risk of infection: a case control study
    Marlijn Kamps
    Department of Intensive Care, Radboud University Nijmegen Medical Centre PO Box 9101, 6500 HB Nijmegen, The Netherlands
    Crit Care 15:R48. 2011
    ..Prolonged hypothermic treatment may further enhance the risk of infection. Selective decontamination of the digestive tract (SDD) reduces the risk of respiratory tract infections...
  18. ncbi Microbial contamination of toothbrushes and their decontamination
    P Nelson Filho
    Department of Pediatric Dentistry, School of Dentistry of Ribeirao Preto, University of Sao Paulo, Brazil
    Pediatr Dent 22:381-4. 2000
    ....
  19. ncbi Evaluation of five decontamination methods for filtering facepiece respirators
    Dennis J Viscusi
    National Institute for Occupational Safety and Health, National Personal Protective Technology Laboratory, Pittsburgh, PA 15236, USA
    Ann Occup Hyg 53:815-27. 2009
    ..One possible strategy to mitigate a respirator shortage is to reuse FFRs following a biological decontamination process to render infectious material on the FFR inactive...
  20. ncbi Analysis of residual chemicals on filtering facepiece respirators after decontamination
    W B Salter
    Applied Research Associates, Tyndall Air Force Base, Florida 32403, USA
    J Occup Environ Hyg 7:437-45. 2010
    ..be established, many parameters affecting respiratory protection must be measured: biocidal efficacy of the decontamination treatment, filtration performance, pressure drop, fit, and toxicity to the end user post treatment...
  21. ncbi Selective decontamination of digestive tract in intensive care
    Henri A Verbrugh
    Lancet 362:2117-8. 2003
  22. ncbi An improved method for emergent decontamination of ocular and dermal hydrofluoric acid splashes
    Kjell Soderberg
    Medical Service, Avesta Polarit, Torshalla, Sweden
    Vet Hum Toxicol 46:216-8. 2004
    ..This report describes the utilization of Hexafluorine--a hypertonic, amphoteric, chelating decontamination solution--in workplaces where water decontamination followed by calcium gluconate inunction failed to prevent ..
  23. ncbi Probiotics versus antibiotic decontamination of the digestive tract: infection and mortality
    Guy J Oudhuis
    Department of Medical Microbiology, NUTRIM School for Nutrition, Toxicology and Metabolism, Maastricht University Medical Centre, PO Box 5800, 6202 AZ Maastricht, The Netherlands
    Intensive Care Med 37:110-7. 2011
    Selective decontamination of the digestive tract (SDD) has been shown to decrease the infection rate and mortality in intensive care units (ICUs); Lactobacillus plantarum 299/299v plus fibre (LAB) has been used for infection prevention ..
  24. ncbi [Caustic injuries of the eye, skin and the gastrointestinal tract]
    Florian Eyer
    Toxikologische Abteilung der II Medizinischen Klinik, Klinikum rechts der Isar Technische Universität München, Munchen
    Ther Umsch 66:379-86. 2009
    ..All chemical exposures to the eye require immediate decontamination by copious irrigation with an aqueous solution for at least 15-30 minutes up to two hours in single cases of ..
  25. ncbi Development of a test system to evaluate procedures for decontamination of respirators containing viral droplets
    Evanly Vo
    National Institute for Occupational Safety and Health, National Personal Protective Technology Laboratory, Pittsburgh, PA 15236, USA
    Appl Environ Microbiol 75:7303-9. 2009
    The aim of this study was to develop a test system to evaluate the effectiveness of procedures for decontamination of respirators contaminated with viral droplets. MS2 coliphage was used as a surrogate for pathogenic viruses...
  26. ncbi Investigations of a prion infectivity assay to evaluate methods of decontamination
    Guillaume Fichet
    STERIS Laboratory, CEA DSV IMETI SEPIA, Fontenay aux Roses, France
    J Microbiol Methods 70:511-8. 2007
    ..and various industrial surfaces, but there is currently no standard, accepted model to evaluate surface prion decontamination. In this report, a set of both in vitro and in vivo methods were investigated based on the contamination of ..
  27. ncbi Hydrogen peroxide vapour decontamination in an overcrowded tertiary care referral centre: some practical answers
    J A Otter
    J Hosp Infect 62:384-5. 2006
  28. ncbi Oral decontamination with chlorhexidine reduces the incidence of nosocomial pneumonia
    Ilias I Siempos
    Crit Care 11:402; author reply 402. 2007
  29. ncbi Decontamination of polymerase chain reaction reagents using DEAE-cellulose
    S A Glushkov
    Institute of Cytology and Genetics, Siberian Branch of Russian Academy of Sciences, Novosibirsk 630090, Russian Federation
    Anal Biochem 393:135-7. 2009
    ..from contaminating nucleic acid using DEAE-cellulose and present the analysis of this technique for both decontamination efficiency and an effect on the reagent activity...
  30. ncbi Microbial contamination of tooth brushes and their decontamination
    S S Bhat
    Department of Pedodontics and Preventive Dentistry, Yenepoya Dental College, Mangalore, Karnataka
    J Indian Soc Pedod Prev Dent 21:108-12. 2003
    ..Disappearance of growth of microorganisms was seen in Gp I and Gp II and remnants of growth seen in Gp III. It can be concluded that the use of disinfectant is a must for every individual at regular intervals...
  31. ncbi Water decontamination of chemical skin/eye splashes: a critical review
    Alan H Hall
    Toxicology Consulting and Medical Translating Services, Elk Mountain, Wyoming 82324, USA
    Cutan Ocul Toxicol 25:67-83. 2006
    Skin/eye chemical splashes are a significant workplace problem. Initial water decontamination is usually recommended, but there are few well-conducted experimental animal and human studies of efficacy...
  32. ncbi Development of a test system to apply virus-containing particles to filtering facepiece respirators for the evaluation of decontamination procedures
    Edward Fisher
    EG and G Technical Services, Inc, Pittsburgh, Pennsylvania 15236, USA
    Appl Environ Microbiol 75:1500-7. 2009
    ..substrates (coupons) was constructed and validated as part of a method to assess the virucidal efficacy of decontamination procedures for filtering facepiece respirators...
  33. ncbi Bone microbial decontamination agents in osseous grafting: an in vitro study with fresh human explants
    Fernando Verdugo
    VA Hospital, Greater Los Angeles, Healthcare System, Los Angeles, CA, USA
    J Periodontol 82:863-71. 2011
    ..Establishing a safe prophylactic antimicrobial protocol in bone grafting may enhance osseous volume outcomes. The purpose of this in vitro study is to assess human osteoblast response and safety after explant antimicrobial exposure...
  34. ncbi Tuberculosis diagnosis and multidrug resistance testing by direct sputum culture in selective broth without decontamination or centrifugation
    Louis Grandjean
    Departamento de Microbiologia, Facultad de Ciencias, Laboratorios de Investigación y Desarrollo, Universidad Peruana Cayetano Heredia, Lima, Peru
    J Clin Microbiol 46:2339-44. 2008
    Tuberculosis culture usually requires sputum decontamination and centrifugation to prevent cultures from being overgrown by contaminating bacteria and fungi...
  35. ncbi Efficient decontamination of zearalenone, the mycotoxin of cereal pathogen, by transgenic yeasts through the expression of a synthetic lactonohydrolase gene
    Naoko Takahashi-Ando
    Laboratory for Remediation Research, Plant Science Center, RIKEN, 1-7-22 Suehiro, Tsurumi, Yokohama, Kanagawa, 230-0045, Japan
    Appl Microbiol Biotechnol 67:838-44. 2005
    ..The result suggests that incomplete ZEN detoxification attributed to the action of an endogenous yeast beta-reductase can be overcome by simply increasing the expression of the detoxifying gene...
  36. ncbi Alteromonas prolidase for organophosphorus G-agent decontamination
    T C Cheng
    Environmental Technology Team, US Army Edgewood Research, Development and Engineering Center, Aberdeen, MD 21010, USA
    Chem Biol Interact 119:455-62. 1999
    ..sp.JD6.5 with the goal of developing strategies for long-term storage and decontamination have been successfully achieved...
  37. ncbi A standardized comparison of commercially available prion decontamination reagents using the Standard Steel-Binding Assay
    Julie Ann Edgeworth
    MRC Prion Unit, Department of Neurodegenerative Disease, UCL Institute of Neurology, Queen Square, London WC1N 3BG, UK
    J Gen Virol 92:718-26. 2011
    ..transfer infectivity to a suitable host, and much research has been performed to achieve effective prion decontamination of metal surfaces...
  38. ncbi Colonic sterilization for natural orifice translumenal endoscopic surgery (NOTES) procedures: a comparison of two decontamination protocols
    Sharon L Bachman
    Department of Surgery, University of Missouri, One Hospital Drive, Columbia, MO 65212, USA
    Surg Endosc 23:1854-9. 2009
    ..This study aimed to evaluate the effect of two different sterilization protocols on the bacterial counts in the swine colon as preparation for natural orifice translumenal endoscopic surgery (NOTES) surgery...
  39. ncbi A method to determine the available UV-C dose for the decontamination of filtering facepiece respirators
    E M Fisher
    National Institute for Occupational Safety and Health, National Personal Protective, Technology Laboratory, Pittsburgh, PA 15236, USA
    J Appl Microbiol 110:287-95. 2011
    To develop a method to assess model-specific parameters for ultraviolet-C (UV-C, 254 nm) decontamination of filtering facepiece respirators (FFRs).
  40. ncbi Decontamination of prion protein (BSE301V) using a genetically engineered protease
    J Dickinson
    Health Protection Agency, Porton Down, Salisbury, UK
    J Hosp Infect 72:65-70. 2009
    ..This study demonstrates the potential for thermostable proteases to be developed as effective inactivation processes for prion agents in healthcare management...
  41. ncbi Analysis of hydrofluoric acid penetration and decontamination of the eye by means of time-resolved optical coherence tomography
    Felix Spöler
    Institute of Semiconductor Electronics, RWTH Aachen University, Sommerfeldstrasse 24, 52074 Aachen, Germany
    Burns 34:549-55. 2008
    So far the study of chemical burns has lacked techniques to define penetration kinetics and the effects of decontamination within biological structures...
  42. ncbi Pulsed-light system as a novel food decontamination technology: a review
    N Elmnasser
    Laboratoire d Analyse, de Traitement et de Valorisation des Polluants de l Environnement et de Produits Faculte de Pharmacie de Monastir, Rue Avicenne, 5000 Monastir, Tunisie
    Can J Microbiol 53:813-21. 2007
    ..It appears to constitute a good alternative or a complement to conventional thermal or chemical decontamination processes...
  43. ncbi Cleanability of dental instruments--implications of residual protein and risks from Creutzfeldt-Jakob disease
    J T Walker
    HPA Centre for Emergency Preparedness and Response, Porton Down, Salisbury, SP4 0JG
    Br Dent J 203:395-401. 2007
    ....
  44. ncbi Improved laboratory safety by decontamination of unstained sputum smears for acid-fast microscopy
    Luiz Roberto Bigão Giacomelli
    Departamento de Analises Clinicas, Universidade Estadual de Maringa, PR, Brazil
    J Clin Microbiol 43:4245-8. 2005
    ..7% for 1 min (tube technique) or for 10 min (slide technique) were effective in decontaminating sputum smears and preserved cell morphology and quantitative acid-fast microscopy results...
  45. ncbi Comparison of two concentrations of NALC-NaOH for decontamination of sputum for mycobacterial culture
    R L Peres
    Nucleo de Doencas Infecciosas, Universidade Federal do Espirito Santo, Vitoria, Espirito Santo, Brazil
    Int J Tuberc Lung Dis 13:1572-5. 2009
    ..of sodium hydroxide (NaOH) in the N-acetyl-L-cysteine-sodium hydroxide (NALC-NaOH) method for sputum decontamination on smear and culture positivity and the proportion of contaminated cultures: 14% of cultures were ..
  46. ncbi Point-of-care controls for nosocomial legionellosis combined with chlorine dioxide potable water decontamination: a two-year survey at a Welsh teaching hospital
    I K Hosein
    Infection Prevention and Control Department, Cardiff and Vale NHS Trust, University Hospital of Wales, Heath Park, Cardiff CF14 4XW, Wales, UK
    J Hosp Infect 61:100-6. 2005
    ....
  47. ncbi A pandemic influenza preparedness study: use of energetic methods to decontaminate filtering facepiece respirators contaminated with H1N1 aerosols and droplets
    Brian K Heimbuch
    Applied Research Associates, Tyndall Air Force Base, 104 Research Road, Panama City, FL 32403, USA
    Am J Infect Control 39:e1-9. 2011
    ..The focus of this research effort was on evaluating the ability of microwave-generated steam, warm moist heat, and ultraviolet germicidal irradiation at 254 nm to decontaminate H1N1 influenza virus...
  48. ncbi Infectivity of prion protein bound to stainless steel wires: a model for testing decontamination procedures for transmissible spongiform encephalopathies
    Zheng-Xin Yan
    SMP GmbH Pruefen Validieren Forschen, Tubingen, Germany
    Infect Control Hosp Epidemiol 25:280-3. 2004
    ..wires contaminated with infectious brain materials as transfer vehicles, and, based on this model, to test decontamination procedures against the infectious prion proteins on the steel wires as a near real situation bioassay...
  49. ncbi Selective decontamination of digestive tract in intensive care
    Mohit Sahni
    Lancet 362:2119; author reply 2119-20. 2003
  50. ncbi Intralaboratory reproducibility of the German test method of prEN ISO 15883-1 for determination of the cleaning efficacy of washer-disinfectors for flexible endoscopes
    B Zühlsdorf
    Technische Hygiene, Charite Universitatsmedizin Berlin, Campus Benjamin Franklin, Hindenburgdamm 27, 12203 Berlin, Germany
    J Hosp Infect 59:286-91. 2005
    ..2 (range: 1.6-3.2) and excellent visible cleanliness of the test pieces. We found that the prEN ISO 15883-1 German test method leads to reproducible and valid results, and is suitable for determining the cleaning efficacy in WDs...
  51. ncbi Decontamination of chemical and biological warfare agents with a single multi-functional material
    Gabi Amitai
    McGowan Institute for Regenerative Medicine, University of Pittsburgh, 450 Technology Drive, Pittsburgh, PA 15219, USA
    Biomaterials 31:4417-25. 2010
    ..dimethylacrylamide-methacrylate (DMAA-MA) co-polymer backbone that support both chemical and biological agent decontamination. Polyurethanes containing the redox enzymes glucose oxidase and horseradish peroxidase can convert halide ..
  52. ncbi Comparisons of protocols for decontamination of environmental ice samples for biological and molecular examinations
    S O Rogers
    Department of Biological Sciences, Bowling Green State University, Bowling Green, Ohio 43403, USA
    Appl Environ Microbiol 70:2540-4. 2004
    ..We report herein a systematic comparative study of several decontamination protocols...
  53. ncbi Resistance of transmissible spongiform encephalopathy agents to decontamination
    D M Taylor
    SEDECON 2000, Edinburgh, UK
    Contrib Microbiol 11:136-45. 2004
  54. ncbi Effects on instruments of the World Health Organization--recommended protocols for decontamination after possible exposure to transmissible spongiform encephalopathy-contaminated tissue
    Stanley A Brown
    United States Food and Drug Administration, Center of Devices and Radiological Health, Office of Science and Technology, Rockville, MD 20850, USA
    J Biomed Mater Res B Appl Biomater 72:186-90. 2005
    ..by the World Health Organization (WHO) and Centers for Disease Control and Prevention (CDC) that rigorous decontamination protocols be used on surgical instruments that have been exposed to tissue possibly contaminated with ..
  55. ncbi Tackling contamination of the hospital environment by methicillin-resistant Staphylococcus aureus (MRSA): a comparison between conventional terminal cleaning and hydrogen peroxide vapour decontamination
    G L French
    Department of Infection, King s College London, North Wing, St Thomas Hospital, UK
    J Hosp Infect 57:31-7. 2004
    ..by MRSA, and compared the effectiveness of standard cleaning with a new method of hydrogen peroxide vapour decontamination. MRSA contamination, measured by surface swabbing was compared before and after terminal cleaning that ..
  56. ncbi Detection of prion after decontamination procedures: comparative study of standard Western blot, filter retention and scrapie-cell assay
    J Solassol
    , UPR 1142 du CNRS, 141 rue de la Cardonille, 34396 Montpellier Cedex 05, France
    J Hosp Infect 57:156-61. 2004
    ..problem because the infectious agent exhibits an unusual resistance to conventional chemical and physical decontamination methods...
  57. ncbi The role of selective digestive decontamination for reducing infection in patients undergoing liver transplantation: a systematic review and meta-analysis
    Nasia Safdar
    Section of Infectious Diseases, Department of Internal Medicine, University of Wisconsin Medical School, Madison, WI, USA
    Liver Transpl 10:817-27. 2004
    Selective digestive decontamination (SDD) refers to the use of antimicrobials to reduce the burden of aerobic gram-negative bacteria and/or yeast in the intestinal tract to prevent infections caused by these organisms...
  58. ncbi Biodegradation of ochratoxin A by Aspergillus section Nigri species isolated from French grapes: a potential means of ochratoxin A decontamination in grape juices and musts
    Hend Bejaoui
    , , Auzeville-Tolozane, Castanet-Tolosan, France
    FEMS Microbiol Lett 255:203-8. 2006
    ..After 9 days of incubation, OTalpha had decreased, whereas an unknown compound appeared. A. niger could be the first interesting species for OTA detoxification processes, followed by A. japonicus...
  59. ncbi Chemical and biological weapons. Implications for anaesthesia and intensive care
    S M White
    Department of Anaesthesia, Guy's and St Thomas' Hospital Trust, St Thomas' Street, London SE1 9RT, UK
    Br J Anaesth 89:306-24. 2002
    ..The specific roles of the anaesthetist and intensivist in treatment are highlighted...
  60. ncbi Influence on outcome of ventilator-associated pneumonia in multiple trauma patients with head trauma treated with selected digestive decontamination
    Marc Leone
    Intensive Care Unit and Trauma Center, Nord Hospital, Marseilles University Hospital System, Marseilles School of Medicine, Marseilles, France
    Crit Care Med 30:1741-6. 2002
    ..In multiple trauma, the use of selective digestive decontamination has been reported to decrease morbidity and mortality associated with pneumonia...
  61. ncbi Gastrointestinal decontamination of the poisoned patient
    Spencer Greene
    Department of Emergency Medicine, Wright State University Boonshoft School of Medicine, Dayton, OH 45429, USA
    Pediatr Emerg Care 24:176-86; quiz 187-9. 2008
    Gastrointestinal decontamination has been a historically accepted modality in the emergency management of oral intoxicants...
  62. ncbi The effect of multiple cycles of contamination, detergent washing, and disinfection on the development of biofilm in endoscope tubing
    Karen Vickery
    Department of Plastic and Reconstructive Surgery, Liverpool Hospital and Surgical Infection Research Group, South Western Clinical School, University of New South Wales, Sydney, Australia
    Am J Infect Control 37:470-5. 2009
    ..Biofilm bacteria are firmly attached to one another and to the substrate by exopolysaccharide, making them difficult to remove. We analyzed the effect of 20 wash/contamination cycles on biofilm formation...
  63. ncbi Limiting the use of gastrointestinal decontamination does not worsen the outcome from deliberate self-poisoning
    M Ardagh
    Emergency Department, Christchurch Hospital
    N Z Med J 114:423-5. 2001
    ..To review the current epidemiology of patients with deliberate self-poisoning presenting to Christchurch Emergency Department, and to compare this with 1996, 1992, and 1989 data...
  64. ncbi Relationship between methodological trial quality and the effects of selective digestive decontamination on pneumonia and mortality in critically ill patients
    C A van Nieuwenhoven
    Department of Internal Medicine, Division of Infectious Diseases and AIDS, University Hospital, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands
    JAMA 286:335-40. 2001
    Although meta-analyses of randomized trials have shown that selective digestive decontamination (SDD) prevents nosocomial pneumonia in critically ill patients, the influence of trial quality on the effectiveness of SDD has not been ..
  65. ncbi Survival benefit of the full selective digestive decontamination regimen
    Luciano Silvestri
    Unit of Anesthesia and Intensive Care, Department of Emergency, Presidio Ospedaliero di Gorizia, 34170 Gorizia, Italy
    J Crit Care 24:474.e7-14. 2009
    We assessed the impact of the full protocol of selective decontamination of the digestive tract (SDD) using parenteral and enteral antimicrobials on mortality.
  66. ncbi Decontamination of multiple casualties who are chemically contaminated: a challenge for acute hospitals
    Simon F J Clarke
    Emergency Department, Frimley Park NHS Foundation Trust, Portsmouth Road, Frimley, Camberley, Surrey GU16 7UJ, UK
    Prehosp Disaster Med 23:175-81. 2008
    ..The risks and potential consequences of this gap in resilience are discussed and a number of possible practical solutions are proposed...
  67. ncbi In situ decontamination of medical wastes using oxidative agents: a 16-month study in a polyvalent intensive care unit
    B Coronel
    Intensive Care Unit, Edouard Herriot Hospital, Lyon, Cedex, France
    J Hosp Infect 50:207-12. 2002
    ..Aero-contamination of the ward was unchanged. Computer control allowed all events to be tracked. On-site medical waste treatment appears to be an efficient alternative to the usual centralized collection and treatment...
  68. ncbi Potential agents of chemical warfare. Worst-case scenario protection and decontamination methods
    Angeline A Lazarus
    Department of Internal Medicine, National Naval Medical Center, 8901 Wisconsin Ave, Bethesda, MD 20889-5600, USA
    Postgrad Med 112:133-40. 2002
  69. ncbi Selective decontamination of the digestive tract reduces mortality in critically ill patients
    Marcus J Schultz
    Department of Intensive Care Medicine, Academic Medical Center, University of Amsterdam, The Netherlands
    Crit Care 7:107-10. 2003
  70. ncbi Selective decontamination of the digestive tract: cumulating evidence, at last?
    Marc J M Bonten
    Department of Internal Medicine, Division of General Medicine, Infectious Diseases and Geriatrics, Eijkman Winkler Institute for Microbiology, Inflammation and Infectious Diseases, University Medical Centre Utrecht, The Netherlands
    Semin Respir Crit Care Med 27:18-22. 2006
    Selective decontamination of the digestive tract (SDD), an infection-control strategy designed to prevent nosocomial pneumonia in mechanically ventilated patients, has been implemented in numerous studies for more than 2 decades, but its ..
  71. ncbi Effect of prion decontamination protocols on nickel-titanium rotary surfaces
    David Sonntag
    Department of Operative Dentistry, Philipps Universitat Marburg, Georg Voigt Strasse 3, 35033 Marburg, Germany
    J Endod 33:442-6. 2007
    b>Decontamination of instruments is a prerequisite for their potential reuse but may affect surface integrity. Hence, the effect of prion removal protocols on 7 brands of nickel-titanium files was investigated...
  72. ncbi Selective decontamination of the digestive tract reduces bacterial bloodstream infection and mortality in critically ill patients. Systematic review of randomized, controlled trials
    L Silvestri
    Department of Anaesthesia and Intensive Care, Presidio Ospedaliero, Gorizia, Italy
    J Hosp Infect 65:187-203. 2007
    A systematic review and meta-analysis of randomized controlled trials (RCTs) of selective decontamination of the digestive tract (SDD) was undertaken to evaluate the impact of this procedure on bacterial bloodstream infection and ..
  73. ncbi Decontamination of orthodontic bands following size determination and cleaning
    P E Benson
    Department of Oral Health and Development, Institution School of Clinical Dentistry, Claremont Crescent, Sheffield, S10 2TA, UK
    J Orthod 34:18-24. 2007
    ..To measure the effectiveness of ultrasonic cleaning for decontaminating orthodontic molar bands following size determination using a quantitative antibody capture assay technique...
  74. ncbi Alfalfa seed decontamination in a Salmonella outbreak
    Christopher J Gill
    Oregon Department of Human Services, Portland, Oregon, USA
    Emerg Infect Dis 9:474-9. 2003
    ..However, little is known about the effectiveness of decontamination at preventing human disease...
  75. ncbi [Nerve gas--guidelines for care of victims of terrorism]
    Pål Aas
    Forsvarets forskningsinstitutt, 2027 Kjeller
    Tidsskr Nor Laegeforen 125:731-5. 2005
    ..This involves decontamination of patients, establishment of routines to avoid contamination of hospitals, and the ability to determine if ..
  76. ncbi Risks posed by mystery illness
    Emma Wilkinson
    Nurs Times 102:23-4. 2006
    ..Nurses must be aware of the protocols to follow to ensure their own safety and that of other patients. This article discusses the national advice in dealing with incidents or outbreaks of unusual illness...
  77. ncbi Manual methods are suboptimal compared with automated methods for cleaning of single-use biopsy forceps
    M J Alfa
    Department of Medical Microbiology and Infectious Diseases, St Boniface Research Centre, St Boniface General Hospital, Winnipeg, Manitoba, Canada
    Infect Control Hosp Epidemiol 27:841-6. 2006
    ..The objective of this study was to determine the cleaning efficacy of automated narrow-lumen sonic irrigation cleaning, sonication-only cleaning, and manual cleaning for biopsy forceps...
  78. ncbi Chemical or biological terrorist attacks: an analysis of the preparedness of hospitals for managing victims affected by chemical or biological weapons of mass destruction
    Russell L Bennett
    Department of Health Policy and Management, School of Public Health, College of Public Service, Jackson State University, Jackson Medical Mall, 350 W Woodrow Wilson Ave, Suite 2301 A, Jackson, Mississippi, USA
    Int J Environ Res Public Health 3:67-75. 2006
    ..survey, the availability of functional preparedness plans, specific preparedness education/training, decontamination facilities, surge capacity, pharmaceutical supplies, and laboratory diagnostic capabilities of hospitals were ..
  79. ncbi Truth hurts--hard lessons from Australia's largest mass casualty exercise with contaminated patients
    Nicholas A Edwards
    Intensive Care Unit, Royal Adelaide Hospital, Adelaide, South Australia, Australia
    Emerg Med Australas 18:185-95. 2006
    ..by the exercise, which we believe have enormous implications for the development of hospital chemical, biological or radiological plans and the likelihood of their success--hospital security, crowd control and decontamination.
  80. ncbi A laboratory evaluation of the decontamination properties of microfibre cloths
    G Moore
    School of Applied Sciences, University of Wales Institute, Cardiff, UK
    J Hosp Infect 64:379-85. 2006
    ..Different makes of microfibre cloths have different characteristics, and the name 'microfibre' should not imply superior cleaning efficacy...
  81. ncbi Safety evaluation of single-use medical devices after submission to simulated reutilization cycles
    Mônica Valero Da Silva
    Fundacao Universidade de Brasilia, Faculdade de Ciencias da Saude, Departamento de Farmacia, Campus Universitário Asa Norte, CEP 70910 900, Brazilia, DF, Brazil
    J AOAC Int 88:823-9. 2005
    ..Microbial counts as high as 10(3) CFU were evident even after the 10th reprocessing cycle, besides scratched and damaged surfaces observed by SEM. Risk-benefit viewpoints are discussed...
  82. ncbi Medical resources and requirements for responding to radiological terrorism
    Fred A Mettler
    Department of Radiology, New Mexico Federal Regional Medical Center, 1501 San Pedro Blvd, Albuquerque, NM 87108, USA
    Health Phys 89:488-93. 2005
    ..Although the requirements for medical management are clear, the available resources have not been applied in a manner that results in adequate preparedness for radiological events...
  83. ncbi [In-hospital management of victims of chemical weapons of mass destruction]
    Alessandro Barelli
    Centro Antiveleni, Servizio di Tossicologia Clinica, Istituto di Anestesiologia e Rianimazione, Universita Cattolica del Sacro Cuore, Largo A Gemelli 8, 00161 Rome, Italy
    Ann Ist Super Sanita 41:93-101. 2005
    ..This review is designed to familiarize readers with the concepts, terminology and key operational considerations that affect the in-hospital management of incidents by chemical weapons...
  84. ncbi Clinical care in the "Hot Zone"
    M Byers
    Academic Department of Military Emergency Medicine, Royal Centre for Defence Medicine, Selly Oak Hospital, Birmingham, UK
    Emerg Med J 25:108-12. 2008
    ..This article discusses the background to the current threat and suggests that, where survivors are present in the "Hot Zone", medical care should be started there to minimise delay and maximise the chances of survival...
  85. ncbi Toxicological aspects of preparedness and aftercare for chemical-incidents
    Michael Schwenk
    Landesgesundheitsamt, Wiederholdstr, 15, 70174 Stuttgart, Germany
    Toxicology 214:232-48. 2005
    ..consult public health services with regard to toxicosurveillance and advice hospitals regarding antidotes, decontamination procedures and shelters...
  86. ncbi Unmasking procedures following a chemical attack: a critical review with recommendations
    David B Rosenberg
    Battalion Surgeon, 5th Battalion, 10th Marines, 2nd Marine Division Camp, Lejeune, NC 28542, USA
    Mil Med 170:599-601. 2005
    ..Easy to implement recommendations are made, both to prevent lethal exposures and to better treat toxicity should prevention fail...
  87. ncbi Rapid recontamination with MRSA of the environment of an intensive care unit after decontamination with hydrogen peroxide vapour
    K J Hardy
    West Midlands Public Health Laboratory, Health Protection Agency, Heartlands Hospital, Bordesley Green East, Birmingham, UK
    J Hosp Infect 66:360-8. 2007
    ..level of environmental contamination with MRSA, assess the effectiveness of hydrogen peroxide vapour (HPV) decontamination and determine the rate of environmental recontamination. MRSA was isolated from 11...
  88. ncbi Civilian exposure to toxic agents: emergency medical response
    David Baker
    , , 75574 Paris 15, France
    Prehospital Disaster Med 19:174-8. 2004
    ..Within an organized and protected perimeter, triage and decontamination (if the agent is persistent) can proceed while emergency medical care is provided at the same time...
  89. ncbi Mass casualty management for radiological and nuclear incidents
    S A Bland
    Defence Medical Services, Royal London Hospital, London E1 1BB
    J R Army Med Corps 150:27-34. 2004
    ..From these findings, appropriate management based upon the needs and available resources can be planned. This includes triage for surgery and the use of the expectant (T4) triage category...
  90. ncbi [Preventive strategies for nosocomial pneumonia]
    Kazui Soma
    Department of Emergency and Critical Care Medicine, Kitasato Univerisity, School of Medicine, Kanagawa, Japan
    Nippon Geka Gakkai Zasshi 105:716-9. 2004
    ..Useful preventative strategies include subglottic suctioning of pooled secretions just above the endotracheal tube cuff and oral care because of the pathogenesis of VAP...
  91. ncbi How would you respond to a chemical release?
    Carolin M Reilly
    Central Maine Medical Center, Lewiston, USA
    Nursing 33:36-42; quiz 43. 2003
    ..Whether an industrial accident or an act of terrorism, a chemical release can spell disaster. Here you'll learn to respond appropriately, depending on the type and form of chemical involved...
  92. ncbi Amazing terrorism tool: new foam could revolutionize decon
    Jeff Lindsey
    Estero (Fla.) Fire Rescue, USA
    JEMS 28:84, 86. 2003
  93. ncbi The Army chemical/biological SMART (SMART-CB) team: the nurse's role
    Kenny Barajas
    Walter Reed Army Medical Center, Walter Reed Station, Washington, DC 20012, USA
    Crit Care Nurs Clin North Am 15:257-64. 2003
    ..Early recognition, reporting, decontamination, self-protection, prophylaxis, and treatment are imperative...
  94. ncbi In vitro modeling of dental water line contamination and decontamination
    D A Spratt
    Division of Microbial Diseases, Eastman Dental Institute for Oral Health Care Sciences, UCL, London, UK
    FEMS Microbiol Lett 235:363-7. 2004
    ..The aim of this study was to use an in vitro DUWL to model microbial contamination and evaluate the decontamination efficacy of tetraacetylethylenediamine (TAED) solutions...
  95. ncbi Rapid inactivation of vaccinia virus in suspension and dried on surfaces
    A Ferrier
    , , Grenoble, France
    J Hosp Infect 57:73-9. 2004
    ..Safe decontamination procedures will have to be in place in order to limit the spread of the disease...
  96. ncbi The problem of secondary contamination following chemical agent release
    David Baker
    SAMU 75, Hopital Necker - Enfants Malades, Paris, France
    Crit Care 9:323-4. 2005
  97. ncbi Chemical weapon functional exercise--Cincinnati: observations and lessons learned from a "typical medium-sized" city's response to simulated terrorism utilizing Weapons of Mass Destruction
    Denis J FitzGerald
    Department of Emergency Medicine, University Hospital, Cincinnati, OH 45267 0769, USA
    Public Health Rep 118:205-14. 2003
    ..day that have widespread applicability to health care delivery systems nationwide, especially in the areas of decontamination, triage, on-scene medical care, and victim transportation...
  98. ncbi Operation Castle Cascade: managing multiple casualties from a simulated chemical weapons attack
    David Siegel
    Department of Emergency Medicine, Madigan Army Medical Center, Tacoma, WA 98431, USA
    Mil Med 168:351-4. 2003
    ..Issues relating to on-site chemical identification, triage, decontamination, treatment, casualty collection, and transportation of casualties are addressed in this article.
  99. ncbi Inadequacy of manual cleaning for reprocessing single-use, triple-lumen sphinctertomes: simulated-use testing comparing manual with automated cleaning methods
    Michelle J Alfa
    Department of Clinical Laboratory Science, Wayne State University, Detroit, Michigan, USA
    Am J Infect Control 31:193-207. 2003
    ..Our data validate the efficacy of reprocessing sphinctertomes once with SI-Auto retro-flush cleaning followed by 2 hours of ethylene oxide sterilization...
  100. ncbi An unusual incident: breached 22Na sealed source
    L E Porter
    Washington State University, Pullman, WA 99164, USA
    Health Phys 86:S38-41. 2004
    ..Safety Office were severely taxed during both the immediate reaction and the subsequent several months of decontamination prior to release of the laboratory for unrestricted use of radioactive materials once again...
  101. ncbi Chemical and biological terrorism preparedness for staff development specialists
    Tener Goodwin Veenema
    University of Rochester School of Nursing, NY, USA
    J Nurses Staff Dev 19:218-25; quiz 226-7. 2003
    ....

Research Grants74

  1. Processing of Materials for Improved Biocompatibility
    Michael Matthews; Fiscal Year: 2004
    ..used in biomedical devices such as prostheses and implants by providing a higher level of cleanliness and decontamination, while simultaneously providing sterilization...
  2. Nonheme Diiron Centers and the Biological Oxidation of Hydrocarbons
    STEPHEN LIPPARD; Fiscal Year: 2009
    ..of the molecular mechanisms of O2 activation and substrate hydroxylation provided by this research will advance novel strategies for environmental decontamination and the development of catalysts to convert methane to methanol.
  3. Nonheme Diiron Centers and the Biological Oxidation of Hydrocarbons
    STEPHEN LIPPARD; Fiscal Year: 2009
    ..of the molecular mechanisms of O2 activation and substrate hydroxylation provided by this research will advance novel strategies for environmental decontamination and the development of catalysts to convert methane to methanol.
  4. Nonheme Diiron Centers and the Biological Oxidation of Hydrocarbons
    STEPHEN LIPPARD; Fiscal Year: 2007
    ..molecular mechanisms of 62 activation and substrate hydroxylation provided by this research will advance novel strategies for environmental decontamination and the development of catalysts to convert methane to methanol.
  5. Novel Organophosphorous Hydrolases for Decontamination
    Andrew Mesecar; Fiscal Year: 2007
    ..the focus of intense research efforts aimed at developing these enzymes into products for enzyme- based decontamination. Unfortunately, the enzymes currently in development lack many of the desired properties such as solution ..
  6. Testing Interventions to Human-Generated Occupational Airborne Infections
    Edward A Nardell; Fiscal Year: 2010
    ..We will test both a conventional HEPA filter unit and novel low-maintenance electrostatic air decontamination technology developed for use in outer space...
  7. Testing Interventions to Human-Generated Occupational Airborne Infections
    Edward A Nardell; Fiscal Year: 2010
    ..We will test both a conventional HEPA filter unit and novel low-maintenance electrostatic air decontamination technology developed for use in outer space...
  8. Nonheme Diiron Centers and the Biological Oxidation of Hydrocarbons
    Stephen J Lippard; Fiscal Year: 2010
    ..The ability of these hydrocarbon-consuming "superbugs" to degrade chlorinated hydrocarbons has led to their application in the bioremediation of industrial wastewater, decontamination of seawater, and removal of soil pollutants.
  9. Data Mining Assisted Discovery of Novel Organophosphorou
    Robert Turner; Fiscal Year: 2005
    ..become the focus of intense research efforts aimed at developing these enzymes into products for enzyme-based decontamination. However, currently available enzymes lack many of the desired properties such as solution solubility, ..
  10. ORAL CARE INTERVENTION IN MECHANICALLY VENTILATED ADULTS
    Cindy L Munro; Fiscal Year: 2010
    ..Pre-intubation oral decontamination could reduce risk of VAP and its associated morbidity and mortality...
  11. Nisin as a decontaminant for B. anthracis spores on human skin
    Kenneth Alibek; Fiscal Year: 2007
    ..Many of the decontamination regimens under investigation are too harsh for use on skin...
  12. SPORE PEPTIDOGLYCAN SYNTHESIS IN BACILLUS SUBTILIS
    DAVID POPHAM; Fiscal Year: 2002
    ..Knowledge of principles of endospore resistance properties, dormancy,and longevity may contribute to better decontamination methods and methods for storage and transport of drugs and vaccines...
  13. High Throughput Bioengineering of Detoxification Enzymes
    Margaret Bradley; Fiscal Year: 2003
    ..optimal conditions of assay and other substrates (by us or by collaborators), and iii) finally adding adaptors and modifications to these enzymes for use as biosensors or as a detoxification and/or decontamination tools.
  14. Biofilm Formation by Listeria monocytogenes
    KATHERINE LEMON; Fiscal Year: 2007
    ..This makes decontamination of biofilm-coated surfaces particularly difficult...
  15. Low Temp Decontamination/Sterilize/Dental Handpieces
    Mohamed Labib; Fiscal Year: 2005
    ..This development is expected to reduce DH costs for the dental practice, standardize DH cleaning and lubrication steps, and decrease exposure of dental workers to microbial contamination compared to the current practice. ..
  16. A Randomized Clinical Trial to Prevent Recurrent CA-MRASA Infection
    Loren Miller; Fiscal Year: 2007
    ..Others suggest environmental decontamination to help control recurrences and transmission within households...
  17. Communicore Animal Facility (CAF) Renovation Phase III Part II
    AUGUST BATTLES; Fiscal Year: 2007
    ..will be reconfigured to provide an exit for potentially infectious caging and materials and their efficient decontamination. Additionally, the route of sterile caging into the ABSL3 from the new CAF Annex cage wash will be shortened ..
  18. Alcohol Intoxication and Postburn Intestinal Immunity
    Mashkoor Choudhry; Fiscal Year: 2009
    ..In Specific Aim 2 studies using approaches of selective decontamination of intestine with antibiotics prior to EtOH intoxication and burn injury will determine whether intestinal ..
  19. Alcohol Intoxication and Postburn Intestinal Immunity
    Mashkoor Choudhry; Fiscal Year: 2007
    ..In Specific Aim 2 studies using approaches of selective decontamination of intestine with antibiotics prior to EtOH intoxication and burn injury will determine whether intestinal ..
  20. Alcohol Intoxication and Postburn Intestinal Immunity
    Mashkoor Choudhry; Fiscal Year: 2009
    ..In Specific Aim 2 studies using approaches of selective decontamination of intestine with antibiotics prior to EtOH intoxication and burn injury will determine whether intestinal ..