occupational exposure

Summary

Summary: The exposure to potentially harmful chemical, physical, or biological agents that occurs as a result of one's occupation.

Top Publications

  1. ncbi Toxic potential of materials at the nanolevel
    Andre Nel
    Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles, CA 90095, USA
    Science 311:622-7. 2006
  2. ncbi Changes in DNA methylation patterns in subjects exposed to low-dose benzene
    Valentina Bollati
    Molecular Epidemiology Laboratory, Department of Environmental and Occupational Health, University of Milan, Via San Barnaba 8, 20122 Milan, Italy
    Cancer Res 67:876-80. 2007
  3. ncbi Occupation and risk of parkinsonism: a multicenter case-control study
    Caroline M Tanner
    Department of Clinical Research, The Parkinson s Institute, Sunnyvale, California 94085, USA
    Arch Neurol 66:1106-13. 2009
  4. ncbi A review of carbon nanotube toxicity and assessment of potential occupational and environmental health risks
    Chiu wing Lam
    JSC Toxicology Group, Space Life Sciences, NASA Johnson Space Center, Wyle Laboratories and Department of Pathology and Laboratory Medicine, University of Texas Medical School, Houston, Texas 77058, USA
    Crit Rev Toxicol 36:189-217. 2006
  5. ncbi Epidemiology of lung cancer: ACCP evidence-based clinical practice guidelines (2nd edition)
    Anthony J Alberg
    Hollings Cancer Center, Medical University of South Carolina, 86 Jonathan Lucas St, PO Box 250955, Charleston, SC 29425, USA
    Chest 132:29S-55S. 2007
  6. ncbi Occupation and cancer - follow-up of 15 million people in five Nordic countries
    Eero Pukkala
    Finnish Cancer Registry, Institute for Statistical and Epidemiological Cancer Research, Pieni Roobertinkatu 9, FI 00130, Helsinki, Finland
    Acta Oncol 48:646-790. 2009
  7. ncbi Cohort mortality study of workers exposed to perfluorooctanoic acid
    Kyle Steenland
    Department of Epidemiology, Rollins School of Public Health, Emory University, 1518 Clifton Road NE, Atlanta, GA 30322, USA
    Am J Epidemiol 176:909-17. 2012
  8. ncbi Occupational exposures to polycyclic aromatic hydrocarbons, and respiratory and urinary tract cancers: a quantitative review to 2005
    C Bosetti
    Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy
    Ann Oncol 18:431-46. 2007
  9. ncbi Occupational exposure assessment in carbon nanotube and nanofiber primary and secondary manufacturers
    Matthew M Dahm
    Industrywide Studies Branch, Division of Surveillance, Hazard Evaluations, and Field Studies, 4676 Columbia Parkway, MS R14, Cincinnati, OH 45226, USA
    Ann Occup Hyg 56:542-56. 2012
  10. pmc Persistence of livestock-associated methicillin-resistant Staphylococcus aureus in field workers after short-term occupational exposure to pigs and veal calves
    Brigitte A G L van Cleef
    Centre for Infectious Disease Control Netherlands, RIVM National Institute for Public Health and the Environment, Bilthoven, The Netherlands
    J Clin Microbiol 49:1030-3. 2011

Detail Information

Publications341 found, 100 shown here

  1. ncbi Toxic potential of materials at the nanolevel
    Andre Nel
    Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles, CA 90095, USA
    Science 311:622-7. 2006
    ..The establishment of principles and test procedures to ensure safe manufacture and use of nanomaterials in the marketplace is urgently required and achievable...
  2. ncbi Changes in DNA methylation patterns in subjects exposed to low-dose benzene
    Valentina Bollati
    Molecular Epidemiology Laboratory, Department of Environmental and Occupational Health, University of Milan, Via San Barnaba 8, 20122 Milan, Italy
    Cancer Res 67:876-80. 2007
    ..20). This is the first human study to link altered DNA methylation, reproducing the aberrant epigenetic patterns found in malignant cells, to low-level carcinogen exposure...
  3. ncbi Occupation and risk of parkinsonism: a multicenter case-control study
    Caroline M Tanner
    Department of Clinical Research, The Parkinson s Institute, Sunnyvale, California 94085, USA
    Arch Neurol 66:1106-13. 2009
    ..We examined risk of parkinsonism in occupations (agriculture, education, health care, welding, and mining) and toxicant exposures (solvents and pesticides) putatively associated with parkinsonism...
  4. ncbi A review of carbon nanotube toxicity and assessment of potential occupational and environmental health risks
    Chiu wing Lam
    JSC Toxicology Group, Space Life Sciences, NASA Johnson Space Center, Wyle Laboratories and Department of Pathology and Laboratory Medicine, University of Texas Medical School, Houston, Texas 77058, USA
    Crit Rev Toxicol 36:189-217. 2006
    ..The toxicological hazard assessment of potential human exposures to airborne CNTs and occupational exposure limits for these novel compounds are discussed in detail...
  5. ncbi Epidemiology of lung cancer: ACCP evidence-based clinical practice guidelines (2nd edition)
    Anthony J Alberg
    Hollings Cancer Center, Medical University of South Carolina, 86 Jonathan Lucas St, PO Box 250955, Charleston, SC 29425, USA
    Chest 132:29S-55S. 2007
    ..The objective of this study was to summarize the published literature concerning the epidemiology of lung cancer...
  6. ncbi Occupation and cancer - follow-up of 15 million people in five Nordic countries
    Eero Pukkala
    Finnish Cancer Registry, Institute for Statistical and Epidemiological Cancer Research, Pieni Roobertinkatu 9, FI 00130, Helsinki, Finland
    Acta Oncol 48:646-790. 2009
    ..The third essential component is methodological development related to analysis and interpretation of results based on averaged information of exposures and co-factors in the occupational categories...
  7. ncbi Cohort mortality study of workers exposed to perfluorooctanoic acid
    Kyle Steenland
    Department of Epidemiology, Rollins School of Public Health, Emory University, 1518 Clifton Road NE, Atlanta, GA 30322, USA
    Am J Epidemiol 176:909-17. 2012
    ..These results were limited by small numbers and restriction to mortality data, which are of limited relevance for several nonfatal outcomes of a priori interest...
  8. ncbi Occupational exposures to polycyclic aromatic hydrocarbons, and respiratory and urinary tract cancers: a quantitative review to 2005
    C Bosetti
    Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy
    Ann Oncol 18:431-46. 2007
    ....
  9. ncbi Occupational exposure assessment in carbon nanotube and nanofiber primary and secondary manufacturers
    Matthew M Dahm
    Industrywide Studies Branch, Division of Surveillance, Hazard Evaluations, and Field Studies, 4676 Columbia Parkway, MS R14, Cincinnati, OH 45226, USA
    Ann Occup Hyg 56:542-56. 2012
    ..To address this gap, exposure assessments were conducted at six representative sites identified as CNT/CNF primary or secondary manufacturers...
  10. pmc Persistence of livestock-associated methicillin-resistant Staphylococcus aureus in field workers after short-term occupational exposure to pigs and veal calves
    Brigitte A G L van Cleef
    Centre for Infectious Disease Control Netherlands, RIVM National Institute for Public Health and the Environment, Bilthoven, The Netherlands
    J Clin Microbiol 49:1030-3. 2011
    ..However, no information is available about MRSA carriage in humans after short-term occupational exposure to pigs or veal calves...
  11. pmc Occupation and cancer in Britain
    L Rushton
    Department of Epidemiology and Biostatistics, Faculty of Medicine, Imperial College London, St Mary s Campus, Norfolk Place, London W2 1PG, UK
    Br J Cancer 102:1428-37. 2010
    ..We estimated the current burden of cancer in Britain attributable to past occupational exposures for International Agency for Research on Cancer (IARC) group 1 (established) and 2A (probable) carcinogens...
  12. pmc Hematotoxicity in workers exposed to low levels of benzene
    Qing Lan
    Division of Cancer Epidemiology and Genetics, National Cancer Institute NCI, National Institutes of Health NIH, Department of Health and Human Services DHHS, Bethesda, MD 20892, USA
    Science 306:1774-6. 2004
    ..Thus, hematotoxicity from exposure to benzene occurred at air levels of 1 ppm or less and may be particularly evident among genetically susceptible subpopulations...
  13. ncbi Global and gene-specific promoter methylation changes are related to anti-B[a]PDE-DNA adduct levels and influence micronuclei levels in polycyclic aromatic hydrocarbon-exposed individuals
    Sofia Pavanello
    Occupational Health Section, Department of Environmental Medicine and Public Health, University of Padova, Padova, Italy
    Int J Cancer 125:1692-7. 2009
    ..We also evaluated whether PAH-induced DNA methylation states were in turn associated with micronuclei in PBLs, an indicator of chromosomal instability...
  14. ncbi Prevalence and characteristics of hearing problems in a working and non-working Swedish population
    D Hasson
    Department of Physiology and Pharmacology, Karolinska Institutet, 171 77 Stockholm, Sweden
    J Epidemiol Community Health 64:453-60. 2010
    ..How prevalence is affected by SES has not been previously established...
  15. pmc Frequent simian foamy virus infection in persons occupationally exposed to nonhuman primates
    William M Switzer
    HIV and Retrovirology Branch, Division of AIDS, STD, and TB Laboratory Research, National Center for HIV, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
    J Virol 78:2780-9. 2004
    ..Our data highlight the importance of studies to better define the public health implications of zoonotic SFV infections...
  16. ncbi Association between chronic obstructive pulmonary disease and employment by industry and occupation in the US population: a study of data from the Third National Health and Nutrition Examination Survey
    Eva Hnizdo
    Division of Respiratory Disease Studies, National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, Morgantown, WV 26505, USA
    Am J Epidemiol 156:738-46. 2002
    ..The fraction of COPD attributable to work was estimated as 19.2% overall and 31.1% among never smokers...
  17. ncbi An increased micronucleus frequency in peripheral blood lymphocytes predicts the risk of cancer in humans
    Stefano Bonassi
    Unit of Molecular Epidemiology, National Cancer Research Institute, Genoa, Italy
    Carcinogenesis 28:625-31. 2007
    ..The current wide-spread use of the MN assay provides a valuable opportunity to apply this assay in the planning and validation of cancer surveillance and prevention programs...
  18. pmc Organophosphate pesticide exposure and neurodevelopment in young Mexican-American children
    Brenda Eskenazi
    Center for Children s Environmental Health Research, School of Public Health, University of California, Berkeley, California 94720 7380, USA
    Environ Health Perspect 115:792-8. 2007
    ..Organophosphate (OP) pesticides are widely used in agriculture and homes. Animal studies suggest that even moderate doses are neurodevelopmental toxicants, but there are few studies in humans...
  19. pmc Environmental and occupational causes of cancer: new evidence 2005-2007
    Richard W Clapp
    Boston University School of Public Health, Boston, MA 02118, USA
    Rev Environ Health 23:1-37. 2008
    ..The current state of knowledge is sufficient to compel us to act on what we know. We repeat the call of ecologist Sandra Steingraber: "From the right to know and the duty to inquire flows the obligation to act."..
  20. pmc Occupational, domestic and environmental mesothelioma risks in the British population: a case-control study
    C Rake
    Institute of Cancer Research, Sutton, Surrey, UK
    Br J Cancer 100:1175-83. 2009
    ..Approximately half of the male cases were construction workers, and only four had worked for more than 5 years in asbestos product manufacture...
  21. ncbi Exposure to manufactured nanoparticles in different workplaces
    Derk Brouwer
    TNO Quality of Life, Food and Chemical Safety Analysis, P O Box 360, Utrechtseweg, 3700 AJ Zeist, The Netherlands
    Toxicology 269:120-7. 2010
    ..It is recommended that future workplace exposure studies will be conducted according to a more harmonized approach for analyzing and reporting of the results...
  22. pmc Maternal occupational exposure to organic solvents during early pregnancy and risks of neural tube defects and orofacial clefts
    Tania A Desrosiers
    Department of Epidemiology, Campus Box 7435, University of North Carolina, Chapel Hill, NC 27599, USA
    Occup Environ Med 69:493-9. 2012
    ..National Birth Defects Prevention Study, the authors examined the relation between maternal occupational exposure to aromatic solvents, chlorinated solvents and Stoddard solvent during early pregnancy and neural tube ..
  23. ncbi Retrospective exposure assessment of perfluorooctanoic acid serum concentrations at a fluoropolymer manufacturing plant
    Susan R Woskie
    Department of Work Environment, University of Massachusetts Lowell, One University Avenue, Lowell, MA 01854, USA
    Ann Occup Hyg 56:1025-37. 2012
    ..8 for internal data comparisons and 0.6 for external data comparisons). These annualized PFOA serum estimates will be used in a series of morbidity and mortality studies of this worker cohort...
  24. ncbi Exposure to substances in the workplace and new-onset asthma: an international prospective population-based study (ECRHS-II)
    Manolis Kogevinas
    Centre for Research in Environmental Epidemiology, Municipal Institute of Medical Research, Barcelona, Spain
    Lancet 370:336-41. 2007
    ..We therefore aimed to estimate the relative and attributable risks of new-onset asthma in relation to occupations, work-related exposures, and inhalation accidents...
  25. ncbi Safety assessment for nanotechnology and nanomedicine: concepts of nanotoxicology
    G Oberdorster
    Department of Environmental Medicine, University of Rochester, 601 Elmwood Avenue, Medical Center, Rochester, NY 14642, USA
    J Intern Med 267:89-105. 2010
    ....
  26. pmc The diesel exhaust in miners study: I. Overview of the exposure assessment process
    Patricia A Stewart
    Division of Cancer Epidemiology and Genetics, US National Cancer Institute, Bethesda, MD 20892, USA
    Ann Occup Hyg 54:728-46. 2010
    ..Method evaluations indicated that the final estimates were consistent with those from alternative time trend models and demonstrated moderate to high agreement with external data...
  27. ncbi The occupational burden of chronic obstructive pulmonary disease
    L Trupin
    Division of Rheumatology, University of California, San Francisco, CA 94143 0920, USA
    Eur Respir J 22:462-9. 2003
    ..b>Occupational exposure during the longest-held job was determined by self-reported exposure to vapours, gas, dust or fumes and ..
  28. pmc Occupational factors and risk of Parkinson's disease: A population-based case-control study
    Jordan A Firestone
    Department of Neurology, University of Washington, Seattle, USA
    Am J Ind Med 53:217-23. 2010
    ..Parkinson's disease (PD) has been associated with various workplace factors, but the evidence is inconsistent...
  29. ncbi Hematological changes among Chinese workers with a broad range of benzene exposures
    Qingshan Qu
    Nelson Institute of Environmental Medicine, New York University School of Medicine, Tuxedo, New York 10987, USA
    Am J Ind Med 42:275-85. 2002
    ..We examine hematological findings and their possible relations with exposure markers validated in a recent biomarker project conducted in Tianjin, China...
  30. ncbi Bioaerosol health effects and exposure assessment: progress and prospects
    J Douwes
    Institute for Risk Assessment Sciences IRAS, Division of Environmental and Occupational Health, Utrecht University, The Netherlands
    Ann Occup Hyg 47:187-200. 2003
    ....
  31. ncbi Ammonium perfluorooctanoate production and occupational mortality
    Jessica I Lundin
    Division of Environmental Health Sciences, University of Minnesota, School of Public Health, Minneapolis, MN 55455, USA
    Epidemiology 20:921-8. 2009
    ..Perfluorooctanoate (PFOA) is a synthetic chemical widely detectable in blood of nonoccupationally exposed persons. Its human health effects are not well-characterized...
  32. pmc The expected burden of mesothelioma mortality in Great Britain from 2002 to 2050
    J T Hodgson
    Epidemiology and Medical Statistics Unit, Health and Safety Executive, Magdalen House, Trinity Road, Bootle, Merseyside L20 3QZ, UK
    Br J Cancer 92:587-93. 2005
    ..Between 1968 and 2050, there will have been approximately 90,000 deaths from mesothelioma in Great Britain, 65,000 of which will occur after 2001...
  33. pmc Vapor, dust, and smoke exposure in relation to adult-onset asthma and chronic respiratory symptoms: the Singapore Chinese Health Study
    Tricia D LeVan
    Arizona Respiratory Center, University of Arizona, Tucson, AZ, USA
    Am J Epidemiol 163:1118-28. 2006
    ..These data support the role of occupational exposures in the etiology of respiratory illness in a population-based cohort in Singapore with a low prevalence of atopic illness...
  34. ncbi Color vision: a sensitive indicator of exposure to neurotoxins
    F Gobba
    Dipartimento di Scienze Igienistiche, Microbiologiche e Biostatistiche, Universita di Modena e Reggio Emilia, Modena, Italy
    Neurotoxicology 21:857-62. 2000
    ....
  35. ncbi Occupational exposure to magnetic fields in case-referent studies of neurodegenerative diseases
    Curtis W Noonan
    Department of Environmental Health, Colorado State University, United States
    Scand J Work Environ Health 28:42-8. 2002
    ..disease were conducted to explore the relationship between these neurodegenerative diseases and occupational exposure to magnetic fields...
  36. pmc Prostate cancer risk from occupational exposure to polycyclic aromatic hydrocarbons interacting with the GSTP1 Ile105Val polymorphism
    Benjamin A Rybicki
    Department of Biostatistics and Research Epidemiology, Henry Ford Health System, Detroit, MI 48202, USA
    Cancer Detect Prev 30:412-22. 2006
    ..An Ile/Val polymorphism in codon 105 of GSTP1 affects its enzymatic activity toward PAH detoxification, a possible mechanism in prostate carcinogenesis...
  37. ncbi Respiratory symptoms and ventilatory function in workers exposed to portland cement dust
    Anne Kristin Møller Fell
    Occupational Health Service, Norcem AS, Brevik, Norway
    J Occup Environ Med 45:1008-14. 2003
    ..3% in the exposed group and 14.0% among the controls. These findings do not support the hypothesis that cement dust exposure has a negative impact on lung function or gives an increase in respiratory symptoms...
  38. pmc Occupational exposure assessment in case-control studies: opportunities for improvement
    K Teschke
    Department of Health Care and Epidemiology, University of British Columbia, Vancouver, BC, V6T 1Z3, Canada
    Occup Environ Med 59:575-93; discussion 594. 2002
    ....
  39. ncbi Demand, control and social climate as predictors of emotional exhaustion symptoms in working Swedish men and women
    Linda L Magnusson Hanson
    Stress Research Institute, Stockholm University, SE 106 91 Stockholm, Sweden
    Scand J Public Health 36:737-43. 2008
    ....
  40. ncbi Retrospective cohort mortality study of workers in a polymer production plant including a reference population of regional workers
    Robin C Leonard
    DuPont Epidemiology Program, DuPont Haskell Laboratory for Health and Environmental Sciences, Newark, DE 19714, USA
    Ann Epidemiol 18:15-22. 2008
    ..S. polymer manufacturing facility, the study objective was to investigate ischemic heart disease (IHD) mortality as well as a broad range of mortality causes for an occupational cohort at the facility...
  41. pmc Mortality and cancer incidence following occupational radiation exposure: third analysis of the National Registry for Radiation Workers
    C R Muirhead
    Health Protection Agency, Centre for Radiation, Chemical and Environmental Hazards, Chilton, Didcot, Oxon OX11 0RQ, UK
    Br J Cancer 100:206-12. 2009
    ..The cancer risk estimates are consistent with values used to set radiation protection standards...
  42. ncbi The effects of work-related maternal risk factors on time to pregnancy, preterm birth and birth weight: the Generation R Study
    A Burdorf
    Department of Public Health, Erasmus MC, University Medical Center Rotterdam, PO Box 2040, 3000 CA Rotterdam, The Netherlands
    Occup Environ Med 68:197-204. 2011
    ..To investigate the influence of maternal working conditions on fertility and pregnancy outcomes...
  43. ncbi Diabetes and cancer in veterans of Operation Ranch Hand after adjustment for calendar period, days of spraying, and time spent in Southeast Asia
    Joel E Michalek
    Department of Epidemiology and Biostatistics, University of Texas Health Science Center at San Antonio, Texas 78229, USA
    J Occup Environ Med 50:330-40. 2008
    ..The Air Force Health Study was launched in 1980 as part of a Federal effort to resolve the Agent Orange issue...
  44. pmc Prevalence of antibodies against avian influenza A (H5N1) virus among Cullers and poultry workers in Ho Chi Minh City, 2005
    Constance Schultsz
    Oxford University Clinical Research Unit, Hospital for Tropical Diseases, Ho Chi Minh City, Vietnam
    PLoS ONE 4:e7948. 2009
    ..We studied the prevalence of antibodies against H5N1 in poultry workers and cullers who were active in the program in Ho Chi Minh City in 2004 and 2005...
  45. ncbi Occupational asthma
    Cristina E Mapp
    Section of Hygiene and Occupational Medicine, Department of Clinical and Experimental Medicine, University of Ferrara, Italy
    Am J Respir Crit Care Med 172:280-305. 2005
    ..Removal of the worker from exposure to the causal agent and treatment with inhaled glucocorticoids lead to a better outcome. Finally, strategies for preventing OA should be implemented and their cost-effectiveness examined...
  46. pmc Clonal comparison of Staphylococcus aureus isolates from healthy pig farmers, human controls, and pigs
    Laurence Armand-Lefevre
    Bacteriology Laboratory, Groupe Hospitalier Bichat Claude Bernard, Paris, France
    Emerg Infect Dis 11:711-4. 2005
    ..This finding suggests a high rate of strain exchange between pigs and farmers...
  47. ncbi The 15-Country Collaborative Study of Cancer Risk among Radiation Workers in the Nuclear Industry: estimates of radiation-related cancer risks
    E Cardis
    International Agency for Research on Cancer, Lyon, France
    Radiat Res 167:396-416. 2007
    ..Further studies will be important to better assess the role of tobacco and other occupational exposures in our risk estimates...
  48. ncbi A practical guide to dose-response analyses and risk assessment in occupational epidemiology
    Kyle Steenland
    Rollins School of Public Health, Emory University, Atlanta, Georgia 30322, USA
    Epidemiology 15:63-70. 2004
    ..Points are illustrated using data from a study of dioxin and cancer...
  49. ncbi Africa's growing cancer burden: environmental and occupational contributions
    Valerie A McCormack
    International Agency for Research on Cancer, Section of Environment and Radiation, 150 cours Albert Thomas, 69372 Lyon Cedex 08, France
    Cancer Epidemiol 36:1-7. 2012
    ..Control of cancer-causing infections and lifestyle-related carcinogens will play a significant role in prevention, but less often addressed are environmental and occupational contributions...
  50. ncbi Occupational exposure to bisphenol-A (BPA) and the risk of self-reported male sexual dysfunction
    D Li
    Division of Research, Kaiser Foundation Research Institute, Kaiser Permanente Northern California, 2000 Broadway, Oakland, CA 94612, USA
    Hum Reprod 25:519-27. 2010
    ..Animal studies have suggested that bisphenol-A (BPA) is a potential human endocrine disrupter; but evidence from human studies is needed...
  51. ncbi Hexavalent chromium and lung cancer in the chromate industry: a quantitative risk assessment
    Robert M Park
    US Department of Health and Human Services, Public Health Service, Centers for Disease Control and Prevention, National Institute for Occupational Safety and Health, 4676 Columbia Parkway, MS C 15, Cincinnati, OH 45226 1998, USA
    Risk Anal 24:1099-108. 2004
    The purpose of this investigation was to estimate excess lifetime risk of lung cancer death resulting from occupational exposure to hexavalent-chromium-containing dusts and mists...
  52. ncbi Occupational exposure to formaldehyde: genotoxic risk evaluation by comet assay and micronucleus test using human peripheral lymphocytes
    Solange Costa
    National Institute of Health, Environmental Health Department, Porto, Portugal
    J Toxicol Environ Health A 74:1040-51. 2011
    ..In order to assess the genotoxic effects of chronic occupational exposure to FA, a group of pathology/anatomy workers was assessed using a micronucleus (MN) test and comet assay...
  53. ncbi Gender differences in occupational exposure patterns
    Amanda Eng
    Centre for Public Health Research, Massey University Wellington Campus, P O Box 756, Wellington, New Zealand
    Occup Environ Med 68:888-94. 2011
    The authors conducted a population-based survey to examine gender differences in occupational exposure patterns and to investigate whether any observed differences are due to: (a) gender differences in occupational distribution; and/or (..
  54. ncbi Manganese accumulation in the CNS and associated pathologies
    Susana Rivera-Mancía
    Neurochemistry Department, National Institute of Neurology and Neurosurgery Manuel Velasco Suarez, Insurgentes Sur 3877, La Fama, Tlalpan, Mexico City 14269, Mexico
    Biometals 24:811-25. 2011
    ..In the case of patients with chronic liver failure it would be worthwhile to test a low-Mn diet in order to ameliorate symptoms of hepatic encephalopathy possibly related to Mn accumulation...
  55. ncbi Breast cancer risk by occupation and industry: analysis of the CECILE study, a population-based case-control study in France
    Sara Villeneuve
    National Institute of Health and Medical Research, Center for Research in Epidemiology and Population Health, Environmental Epidemiology of Cancer, Villejuif, France
    Am J Ind Med 54:499-509. 2011
    ..It has been suggested that certain occupational exposures may play a role in breast cancer etiology. The recognition of high-risk occupations may give clues about potential mammary carcinogens in the work place...
  56. ncbi A 37-year observation of mortality in Chinese chrysotile asbestos workers
    Xiaorong Wang
    Division of Occupational and Environmental Health, School of Public Health and Primary Care, The Chinese University of Hong Kong, Hong Kong, China
    Thorax 67:106-10. 2012
    ..This 37-year prospective cohort study was undertaken to provide additional evidence for mortality risks associated with exposure to chrysotile asbestos...
  57. ncbi Temporal patterns of occupational asbestos exposure and risk of pleural mesothelioma
    Aude Lacourt
    Université Bordeaux Segalen, ISPED, Centre de Recherche INSERM U897, Epidémiologie et Biostatistique, Equipe Associee en Sante Travail, Essat, InVS DST LSTE EA3672, Bordeaux, France
    Eur Respir J 39:1304-12. 2012
    ..These results, based on a large population-based case-control study, underline the need to take into account the temporal pattern of exposure on risk assessment...
  58. pmc The threshold level of urinary cadmium associated with increased urinary excretion of retinol-binding protein and beta 2-microglobulin: a re-assessment in a large cohort of nickel-cadmium battery workers
    Agnès Chaumont
    Unit of Toxicology and Applied Pharmacology, Catholic University of Louvain, Avenue E Mounier 53 02, Brussels B 1200, Belgium
    Occup Environ Med 68:257-64. 2011
    ..On the basis of associations undistorted by smoking and adjusted for covariates, the BMDL5 of CdU for low-molecular-weight proteinuria induced by occupational exposure to Cd can be reliably estimated between 5.5 and 6.6 μg/g creatinine.
  59. ncbi The impact of workplace risk factors on long-term musculoskeletal sickness absence: a registry-based 5-year follow-up from the Oslo health study
    Line Foss
    National Institute of Occupational Health, Oslo, Norway
    J Occup Environ Med 53:1478-82. 2011
    ..To determine the influence of work-related risk factors by gender on long-term sickness absence with musculoskeletal diagnoses (LSM)...
  60. pmc Airborne particulate matter and mitochondrial damage: a cross-sectional study
    Lifang Hou
    Department of Preventive Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA
    Environ Health 9:48. 2010
    ..Although mitochondria are both the major intracellular source and target of oxidative stress, the effect of PM on mitochondria has never been evaluated in exposed individuals...
  61. ncbi Occupational exposures and cancer of the larynx-systematic review and meta-analysis
    Sophie Paget-Bailly
    INSERM, Center for Research in Epidemiology and Population Health, UMRS 1018, Occupational and Environmental Determinants of Health and Versailles Saint Quentin University, UMRS 1018, Villejuif, France
    J Occup Environ Med 54:71-84. 2012
    ..To review epidemiologic data on occupational exposures and laryngeal cancer...
  62. ncbi Occupational exposure to chemical substances and time to pregnancy: a systematic review
    Claudia A Snijder
    Department of Public Health, Erasmus Medical Centre, 3000 CA Rotterdam, The Netherlands
    Hum Reprod Update 18:284-300. 2012
    ..The objective of this review was to systematically summarize the available evidence concerning the influence of occupational exposure to chemicals on time to pregnancy (TTP).
  63. ncbi Harmonization of measurement strategies for exposure to manufactured nano-objects; report of a workshop
    Derk Brouwer
    TNO, The Netherlands Organization for Applied Scientific Research, Research Group Quality and Safety, PO Box 360, 3700 AJ, Zeist, Netherlands
    Ann Occup Hyg 56:1-9. 2012
    ..To make progress in the process of harmonization, it was concluded that achieving agreement among researchers on the preliminary recommendations of the workshop is urgent...
  64. ncbi From cross-tabulations to multipurpose exposure information systems: a new job-exposure matrix
    T Kauppinen
    Finnish Institute of Occupational Health FIOH, Helsinki, Finland
    Am J Ind Med 33:409-17. 1998
    ..The user may also define the final criteria of exposure, and thereby influence the magnitude of misclassification...
  65. ncbi Welding and lung cancer in Central and Eastern Europe and the United Kingdom
    Andrea 't Mannetje
    Centre for Public Health Research, Massey University, Wellington Campus, Wellington, New Zealand
    Am J Epidemiol 175:706-14. 2012
    ..In this population, occupational exposure to welding fumes accounted for approximately 4% of lung cancer cases, to which both stainless and mild ..
  66. pmc Occupational exposure to pesticides increases the risk of incident AD: the Cache County study
    K M Hayden
    Duke University Medical Center, Durham, NC, USA
    Neurology 74:1524-30. 2010
    ..We sought to examine the association of occupational pesticide exposure and the risk of incident dementia and AD in later life...
  67. ncbi The risk of adverse reproductive and developmental disorders due to occupational pesticide exposure: an overview of current epidemiological evidence
    Wojciech Hanke
    Department of Environmental Epidemiology, Nofer Institute of Occupational Medicine, Lodz, Poland
    Int J Occup Med Environ Health 17:223-43. 2004
    ..The data on the effect of occupational exposure to pesticides on birthweight are inconsistent...
  68. pmc Occupational exposure to formaldehyde and alterations in lymphocyte subsets
    H Dean Hosgood
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland 20892 7240, USA
    Am J Ind Med 56:252-7. 2013
    ..Formaldehyde is used in many occupational settings, most notably in manufacturing, health care, and embalming. Formaldehyde has been classified as a human carcinogen, but its mechanism of action remains uncertain...
  69. ncbi Combined analysis of chromosomal aberrations and glutathione S-transferase M1 and T1 polymorphisms in pathologists occupationally exposed to formaldehyde
    Alfredo Santovito
    Department of Animal and Human Biology, University of Torino, Via Accademia Albertina n 13, 10123, Turin, Italy
    Arch Toxicol 85:1295-302. 2011
    ..Our results demonstrate that air FA induces CAs even consequently to low levels of daily exposure, indicating an increased risk of genetic damage for workers exposed to this air pollutant...
  70. pmc Exposure to multiple pesticides and risk of non-Hodgkin lymphoma in men from six Canadian provinces
    Karin Hohenadel
    Occupational Cancer Research Centre, 505 University Avenue, 14th Floor, Toronto, Ontario M5G 1X3, Canada
    Int J Environ Res Public Health 8:2320-30. 2011
    ..These analyses support and extend previous findings that the risk of NHL increases with the number of pesticides used and some pesticide combinations...
  71. ncbi Genotoxicity biomarkers in occupational exposure to formaldehyde--the case of histopathology laboratories
    Carina Ladeira
    Escola Superior de Tecnologia da Saúde de Lisboa, Instituto Politécnico de Lisboa, Portugal
    Mutat Res 721:15-20. 2011
    ..011), with drinkers showing higher mean values. These results provide evidence of the association between occupational exposure to formaldehyde and the presence of genotoxicity biomarkers.
  72. ncbi Comparison of biomechanical loading during use of conventional stud welding equipment and an alternate system
    Nathan B Fethke
    University of Iowa, Occupational and Environmental Health, UI Research Park, Iowa City, IA 52242, USA
    Appl Ergon 42:725-34. 2011
    ..The alternate system appears to be effective in reducing exposure to extreme trunk flexion among stud welders. Continued development of the system should explore features designed to reduce shoulder forces and improve productivity...
  73. ncbi Clinical and immunologic findings of methylene diphenyl diisocyanate-induced occupational asthma in a car upholstery factory
    G Y Hur
    Department of Allergy and Rheumatology, Ajou University School of Medicine, Suwon, Korea
    Clin Exp Allergy 38:586-93. 2008
    ..Although methylene diphenyl diisocyanate (MDI) is widely used in many industries, there have been few immunological studies of MDI-induced occupational asthma...
  74. ncbi Unknown fever and back pain caused by Bartonella henselae in a veterinarian after a needle puncture: a case report and literature review
    Jen Wei Lin
    Department of Veterinary Medicine, College of Veterinary Medicine, National Chung Hsing University, Taichung, Taiwan
    Vector Borne Zoonotic Dis 11:589-91. 2011
    ..Through serological testing and molecular identifications, this clinical case was confirmed to be caused by B. henselae...
  75. pmc Mortality from lymphohematopoietic malignancies and brain cancer among embalmers exposed to formaldehyde
    Michael Hauptmann
    Department of Bioinformatics and Statistics, Netherlands Cancer Institute, Amsterdam, The Netherlands
    J Natl Cancer Inst 101:1696-708. 2009
    ..We investigated the relation of mortality to work practices and formaldehyde exposure levels among these professionals to address cancer risk in the funeral industry...
  76. ncbi Occupational exposure to blood and body fluids among health care workers in a general hospital, China
    Min Zhang
    National Institute for Occupational Health and Poison Control, China CDC, Beijing, China
    Am J Ind Med 52:89-98. 2009
    To understand current status of occupational exposure to blood and body fluids (BBF), and awareness of knowledge about occupational bloodborne pathogen exposures and universal precaution among hospital-based health care workers (HCWs).
  77. ncbi Exposure to thoracic dust, airway symptoms and lung function in cement production workers
    K C Nordby
    National Institute of Occupational Health, PO Box 8149 Dep, NO 0033 Oslo, Norway
    Eur Respir J 38:1278-86. 2011
    ..The results support the hypothesis that exposure to dust in cement production may lead to respiratory symptoms and airway obstruction...
  78. ncbi Comparison of exposure assessment methods for occupational carcinogens in a multi-centre lung cancer case-control study
    Susan Peters
    Institute for Risk Assessment Sciences, Environmental Epidemiology Division, Utrecht University, Utrecht, The Netherlands
    Occup Environ Med 68:148-53. 2011
    ..Different methods have been developed, including case-by-case expert assessment and job-exposure matrices (JEM). The present analyses compare exposure prevalence and risk estimates derived by different exposure assessment methods...
  79. ncbi Formaldehyde and tobacco smoke as alkylating agents: the formation of N-methylenvaline in pathologists and in plastic laminate workers
    Roberto Bono
    Department of Public Health and Microbiology, University of Torino, Torino, Italy
    Sci Total Environ 414:701-7. 2012
    ..All subjects recruited in this study were also tested on their smoking habits...
  80. ncbi Associations of polychlorinated biphenyl exposure and endogenous hormones with diabetes in post-menopausal women previously employed at a capacitor manufacturing plant
    Victoria Persky
    University of Illinois School of Public Health, 1603 West Taylor St, Chicago, IL 60612, USA
    Environ Res 111:817-24. 2011
    ..Possible biologic mechanisms are discussed. This study confirms previous reports relating PCB exposure to diabetes and suggests possible hormonal pathways deserving further exploration...
  81. ncbi Occupational exposure to diesel and gasoline emissions and lung cancer in Canadian men
    Paul J Villeneuve
    Population Studies Division, Health Canada, Ottawa, Ontario, Canada
    Environ Res 111:727-35. 2011
    ..Our objective was to investigate associations between occupational exposure to diesel and gasoline engine emissions and lung cancer...
  82. pmc Occupational exposure to noise and the attributable burden of hearing difficulties in Great Britain
    K T Palmer
    MRC Environmental Epidemiology Unit, Community Clinical Sciences, Southhampton General Hospital, University of Southampton, SO16 6YD, UK
    Occup Environ Med 59:634-9. 2002
    ..the prevalence of self reported hearing difficulties and tinnitus in working aged people from the general population, and to estimate the risks from occupational exposure to noise and the number of attributable cases nationally.
  83. pmc The Diesel Exhaust in Miners Study: II. Exposure monitoring surveys and development of exposure groups
    Joseph B Coble
    Division of Cancer Epidemiology and Genetics, US National Cancer Institute, Bethesda, MD 20892, USA
    Ann Occup Hyg 54:747-61. 2010
    ....
  84. pmc Cancer incidence of 2,4-D production workers
    Carol Burns
    The Dow Chemical Company, Epidemiology, 1803 Building, Midland, MI 48674, USA
    Int J Environ Res Public Health 8:3579-90. 2011
    ..57-0.94), and "other respiratory" cancers (SIR = 3.79, 95% CI 1.22-8.84; 4 of 5 cases were mesotheliomas). Overall, we observed fewer cancer cases than expected, and a non statistically significant increase in the number of NHL cases...
  85. pmc Cardiac autonomic dysfunction from occupational exposure to polycyclic aromatic hydrocarbons
    Mi Sun Lee
    Environmental and Occupational Medicine and Epidemiology Program, Department of Environmental Health, Harvard School of Public Health, Boston, MA 02115, USA
    Occup Environ Med 68:474-8. 2011
    ..This study investigated the association between a biological marker of PAH exposure, assessed by urinary 1-hydroxypyrene (1-OHP), and heart-rate variability in an occupational cohort of boilermakers...
  86. pmc Chronic occupational exposure to hexavalent chromium causes DNA damage in electroplating workers
    Xu Hui Zhang
    Hangzhou Center for Disease Control and Prevention, Hangzhou 310021, PR China
    BMC Public Health 11:224. 2011
    b>Occupational exposure to chromium compounds may result in adverse health effects. This study aims to investigate whether low-level hexavalent chromium (Cr(VI)) exposure can cause DNA damage in electroplating workers.
  87. ncbi Self-assessed and directly measured occupational physical activities--influence of musculoskeletal complaints, age and gender
    I Balogh
    Department of Occupational and Environmental Medicine, University Hospital, Lund SE 221 85, Sweden
    Appl Ergon 35:49-56. 2004
    ..Rate of perceived exertion showed low correlation with heart rate ratio within the two occupational groups, but high, 0.64 when the two groups were combined. Age and complaints explained 31% of the variance for the cleaners...
  88. pmc Inhalable metal-rich air particles and histone H3K4 dimethylation and H3K9 acetylation in a cross-sectional study of steel workers
    Laura Cantone
    Department of Environmental and Occupational Health, Università di Milano and Istituto Di Ricovero e Cura a Carattere Scientifico, and Maggiore Hospital, Mangiagalli and Regina Elena Foundation, Milan, Italy
    Environ Health Perspect 119:964-9. 2011
    ..Whether inhalation of metal components of PM induces histone modifications in human subjects is undetermined...
  89. ncbi Fungal spores: a critical review of the toxicological and epidemiological evidence as a basis for occupational exposure limit setting
    Wijnand Eduard
    National Institute of Occupational Health, Oslo, Norway
    Crit Rev Toxicol 39:799-864. 2009
    ..Mycotoxin-producing and pathogenic species have to be detected specifically, however, because of their higher toxicity...
  90. ncbi Occupation and bladder cancer among men in Western Europe
    Manolis Kogevinas
    Respiratory and Environmental Health Research Unit, IMIM, Barcelona, Spain
    Cancer Causes Control 14:907-14. 2003
    ..We examined which occupations and industries are currently at high risk for bladder cancer in men...
  91. ncbi Theoretical and empirical efficiency of sampling strategies for estimating upper arm elevation
    Per Liv
    Department of Occupational and Public Health Sciences, Centre for Musculoskeletal Research, University of Gavle, Gavle, Sweden
    Ann Occup Hyg 55:436-49. 2011
    ..The study was also designed to compare standard theoretical predictions of sampling efficiency, which rely on several assumptions about the data structure, with 'true' efficiency as determined by bootstrap simulations...
  92. ncbi Upper arm postures and movements in female hairdressers across four full working days
    Jens Wahlström
    Department of Occupational and Environmental Medicine, Umea University Hospital, SE 901 85 Umea, Sweden
    Ann Occup Hyg 54:584-94. 2010
    ....
  93. ncbi Toward risk reduction: predicting the future burden of occupational cancer
    Sally Hutchings
    MRC HPA Centre for Environment and Health, Department of Epidemiology and Biostatistics, Imperial College London, London, United Kingdom
    Am J Epidemiol 173:1069-77. 2011
    ..The authors illustrate the methods by using a range of scenarios for reducing lung cancer due to occupational exposure to respirable crystalline silica...
  94. pmc Vermiculite, respiratory disease, and asbestos exposure in Libby, Montana: update of a cohort mortality study
    Patricia A Sullivan
    Field Studies Branch, Division of Respiratory Disease Studies, National Institute for Occupational Safety and Health, 1095 Willowdale Road, Morgantown, WV 26505, USA
    Environ Health Perspect 115:579-85. 2007
    ..Asbestos-contaminated Libby vermiculite was used in loose-fill attic insulation that remains in millions of homes in the United States, Canada, and other countries...
  95. pmc Neurologic function among termiticide applicators exposed to chlorpyrifos
    K Steenland
    National Institute for Occupational Safety and Health, Cincinnati, OH 45226, USA
    Environ Health Perspect 108:293-300. 2000
    ..Although this was a relatively large study based on a well-defined target population, the workers we studied may not be representative of all exposed workers, and caution should be exercised in generalizing our results...
  96. pmc A framework for integrated environmental health impact assessment of systemic risks
    David J Briggs
    Department of Environmental Epidemiology and Public Health, Imperial College London, Norfolk Place, London, W2 1PG, UK
    Environ Health 7:61. 2008
    ....
  97. ncbi Occupational exposure to solvents and risk of lymphoma subtypes: results from the Epilymph case-control study
    P Cocco
    Department of Public Health, Occupational Health Section, University of Cagliari, Asse Didattico Policlinico Universitario, SS 554, Km 4, 500, 09042 Monserrato Cagliari, Italy
    Occup Environ Med 67:341-7. 2010
    Several studies have suggested an association between occupational exposure to solvents and lymphoma risk. However, findings are inconsistent and the role of specific chemicals is not known...
  98. ncbi Lung cancer risk associated with occupational exposure to nickel, chromium VI, and cadmium in two population-based case-control studies in Montreal
    Rachelle Beveridge
    Departement de Medecine sociale et preventive, Universite de Montreal, Montreal, QC, Canada
    Am J Ind Med 53:476-85. 2010
    ..The purpose of this study was to examine the etiological link between lung cancer and these metals in occupations, that usually entail lower levels of exposure than those seen in historical cohorts...
  99. pmc Antigenic changes in human albumin caused by reactivity with the occupational allergen diphenylmethane diisocyanate
    Adam V Wisnewski
    Department of Internal Medicine, Yale School of Medicine, New Haven, CT 06520, USA
    Anal Biochem 400:251-8. 2010
    ..The study also describes new applications of contemporary proteomic methodology for characterizing and standardizing MDI-albumin conjugates destined for use in clinical research...
  100. ncbi Nanoparticle Emission Assessment Technique (NEAT) for the identification and measurement of potential inhalation exposure to engineered nanomaterials--Part B: Results from 12 field studies
    M Methner
    National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, Cincinnati, Ohio, USA
    J Occup Environ Hyg 7:163-76. 2010
    ..The results demonstrated that the NEAT was useful in evaluating emissions and that readily available engineering controls can be applied to minimize nanomaterial emissions...
  101. pmc Exposure to metal-rich particulate matter modifies the expression of candidate microRNAs in peripheral blood leukocytes
    Valentina Bollati
    Department of Environmental and Occupational Health, Università degli Studi di Milano and IRCCS Fondazione Ca Granda Ospedale Maggiore Policlinico, Center of Molecular and Genetic Epidemiology, Milan, Italy
    Environ Health Perspect 118:763-8. 2010
    ..MicroRNAs (miRNAs) are highly conserved, noncoding small RNAs that regulate the expression of broad gene networks at the posttranscriptional level...

Research Grants82

  1. OCCUPATIONAL ASTHMA ASOCIATED WITH SEAFOOD PROCESSING
    Thomas Robins; Fiscal Year: 2001
    This study proposes to explore the associations between occupational exposure to lobster and saltwater bony fish (pilchard, Cape anchovy, mackerel, light fish, redeye, Cape horse mackerel, lantern fish) and health outcomes expected to be ..
  2. Mustard Gas Exposure and Carcinogenesis of the Lung
    Charles Giardina; Fiscal Year: 2007
    ..Mustard gas is a known mutagen and chronic, occupational exposure is carcinogenic in humans. However, it is not dear whether an acute exposure to mustard agent (e.g...
  3. THE AGRICULTURAL HEALTH STUDY - FIELD STATIONS
    Charles Lynch; Fiscal Year: 2010
    ..In yet another study, results suggest that maternal occupational exposure to agricultural chemicals may increase the risk of giving birth to a child with limb defects...
  4. NIEHS SUPPORT OF THE AHS COHORT STUDY AT NCI
    Charles Knott; Fiscal Year: 2010
    ..In yet another study, results suggest that maternal occupational exposure to agricultural chemicals may increase the risk of giving birth to a child with limb defects...
  5. Analyzer for Monitoring Personal Environmental Exposure to Fluids and Materials
    MATTHEW CUSACK; Fiscal Year: 2010
    ..Other applications for this technology are expected to be part of the GEI, the National Children's Study (NCS), in workplace assessments of occupational exposure, hospitals, or other medical or research settings.
  6. MOLECULAR MECHANISMS OF COMPLEX MIXTURE TOXICITY
    Alvaro Puga; Fiscal Year: 2013
    ..RELEVANCE: Environmental exposure to hexavalent chromium in drinking water and cigarette smoking and occupational exposure in the workplace are often compounded with concomitant exposures to aromatic hydrocarbon procarcinogens, ..
  7. Expanding Vietnamese Community and Academic Infrastructure for Health Research
    Bang H Nguyen; Fiscal Year: 2010
    ..and community health forums;2) research topics - to include diet, smoking cessation, hepatitis B, occupational exposure reduction, comparative- and cost-effectiveness of mobile mammography, and breast, cervical, and colorectal ..
  8. Dietary Lipids and Silica-Accelerated Autoimmunity
    James J Pestka; Fiscal Year: 2013
    ..300,000 Americans and often associated with glomerulonephritis and kidney failure, is increased by occupational exposure (e.g. mining, construction, custodial and manufacturing industries) to silica...
  9. Investigation of Occupational Exposure to and Infection by MRSA in Rural Iowa
    Tara Smith; Fiscal Year: 2012
    ..upon this research and examine the epidemiology of Staphylococcus aureus more broadly in individuals with occupational exposure to livestock and poultry. Our primary objectives are to determine the prevalence of S...
  10. DNA methylation alterations in response to pesticides exposure
    Lifang Hou; Fiscal Year: 2010
    ..In the US, exposure to pesticides is ubiquitous, and over one million people are subjected to high occupational exposure. Pesticides and their residues are pervasive in our environment and our dependence upon pesticides is ..
  11. ABSORPTION, DISTRIBUTION, METABOLISM, AND EXCRETION (ADME) IN MAMMALS
    Jacob McDonald; Fiscal Year: 2013
    ..activities targeted toward the prevention of diseases or adverse effects caused by environmental and occupational exposure to chemical or physical agents...
  12. Mdig gene and histone demethylation in lung cancer
    Fei Chen; Fiscal Year: 2013
    ..The main cause of lung cancer is the environmental and occupational exposure to carcinogens, including tobacco smoking and occupational dust...
  13. ABSORPTION, DISTRIBUTION, METABOLISM, AND EXCRETION (ADME) IN MAMMALS
    Jacob McDonald; Fiscal Year: 2012
    ..activities targeted toward the prevention of diseases or adverse effects caused by environmental and occupational exposure to chemical or physical agents...
  14. GENETIC & ENVIRONMENTAL RISK FACTORS FOR BLADDER CANCER
    Malcolm Pike; Fiscal Year: 2009
    DESCRIPTION (provided by applicant): Occupational exposure to arylamines used in the manufacturing of industrial dyes was the first known cause of human bladder cancer...
  15. BISPHENOL A EFFECTS ON THE PERIPHERAL MECHANISMS OF PENILE ERECTION
    Nestor F Gonzalez-Cadavid; Fiscal Year: 2011
    ..ED affects seriously the quality of life of patients and public health care, and BPA may increase it by occupational exposure. 2. A proof of concept at low doses of BPA may justify future developmental studies. 3...
  16. New Personal Sampling Methods that Conform to an Aerosol Deposition Convention
    DARRAH KAYE SLEETH; Fiscal Year: 2013
    ..become a well qualified, extramurally funded independent researcher that will have an impact in reducing occupational exposure to respiratory hazards...
  17. Occupational exposure to manganese and noise potentiate hearing loss
    Richard J Salvi; Fiscal Year: 2013
    ..We will correlate the degree of hearing impairment and cochlear histopathologies for each treatment paradigm with the Mn concentration in the cochlea. ..
  18. Absorption, distribution, metabolism, excretion (ADME) of chemicals in mammals
    Rochelle W Tyl; Fiscal Year: 2009
    ..activities targeted toward the prevention of diseases or adverse effects caused by environmental and occupational exposure to chemical or physical agents...
  19. Healthy Worker Effect, Occupational Exposure to PM and Cardiopulmonary Mortality
    ELLEN AURA EISEN; Fiscal Year: 2013
    ..5) of traffic-related air pollution, a well established cardiovascular hazard. Moreover, occupational exposure to MWF occurs at high concentrations - orders of magnitude higher than ambient air pollution - providing ..
  20. Prevalance of Community-Acquired MRSA in Live Pigs and thier Human Handlers
    LYNDA UJU ODOFIN; Fiscal Year: 2010
    ..enable public health professionals to set priorities for prevention and control especially with regards to occupational exposure. Also it will reveal the public health implications of MRSA in pigs since pig farmers or handlers maybe a ..
  21. Effect of Manganese Exposure on GABA and Glutamate in Human Brains by MRS
    Ulrike Dydak; Fiscal Year: 2010
    ..PUBLIC HEALTH RELEVANCE: Excessive occupational exposure to manganese in the alloying and steel industry is known to cause Parkinson-like symptoms, which progress ..
  22. A Miniaturized GC with MEMS-Enabled Selective Preconcentration for Monitoring Exp
    Masoud Agah; Fiscal Year: 2013
    ..Development of effective strategies for reducing occupational exposure to HAPs requires accurate, time-resolved measurement of exposure, but doing so is restricted by the ..
  23. Air Pollution Particle Effects on Human Antimycobacterial Immunity
    Stephan K Schwander; Fiscal Year: 2013
    ..epidemiological studies have shown associations of increased incidence of TB with cigarette smoking, occupational exposure to silica, or indoor air pollution, no studies to our knowledge have examined the role of urban air ..
  24. Molecular Genetics of Pathogen Recognition Receptors in COPD
    Tricia D LeVan; Fiscal Year: 2013
    ..b>Occupational exposure to dusts is a significant risk factor for COPD and as much as 15% of COPD cases may be attributable to ..
  25. Studies to Evaluate the Toxic Carcinogenic Potential of Test Agents
    JEFFERY DILL; Fiscal Year: 2009
    ..ABAs have been linked to occupational exposure and human health effects including bronchiolitis obliterans...
  26. New Optics for Trace Level Detection of Toxins in Environmental and Biological Sa
    ZEWU CHEN; Fiscal Year: 2010
    ..The proposed new optics for Cd and Sb will be incredibly valuable to epidemiological studies, occupational exposure monitoring, and medical treatment teams, as well as manufacturers by using the optics in an XRF instrument ..
  27. Plk3 in lung cancer
    Dazhong Xu; Fiscal Year: 2012
    ..and progression are heavily influenced by environmental factors such as smoking and environmental/occupational exposure. Metal elements such as nickel promote lung cancers...
  28. Metal inhibition of the base excision repair enzymes
    Anton Guliaev; Fiscal Year: 2013
    ..The general population is exposed to toxic metals through occupational exposure, food, water, air and a variety of consumer products...
  29. Studies to Evaluate the Toxic Carcinogenic Potential of Test Agents
    JEFFERY DILL; Fiscal Year: 2010
    ..ABAs have been linked to occupational exposure and human health effects including bronchiolitis obliterans...
  30. Studies to Evaluate the Toxic Carcinogenic Potential of Test Agents
    JEFFERY DILL; Fiscal Year: 2011
    ..ABAs have been linked to occupational exposure and human health effects including bronchiolitis obliterans...
  31. Allergic asthma and chromium exposure
    Steven R Patierno; Fiscal Year: 2010
    ..Health has mandated that allergic asthma should be listed as a significant adverse effect associated with occupational exposure to Cr(VI) compounds...
  32. Influence of Endocrine Disruptors on Reproductive Neuroendocrine Function
    JOSEPH RAYMOND KURIAN; Fiscal Year: 2013
    ..As evidence, men with occupational exposure to BPA suffer with reduced sperm counts and exposure to women is associated with repeated miscarriage...
  33. Mechanisms of particulate chromium lung carcinogenesis
    SUSAN M CERYAK; Fiscal Year: 2011
    ..established atmospheric pollutants and human respiratory toxins and carcinogens, while environmental and occupational exposure to chromate continues to loom large as a major public health issue...
  34. Prophylactic Use of Vitamin E for Prevention of Occupational PAH-Induced Damage
    Debbie Mustacich; Fiscal Year: 2009
    ..efficacy of prophylactic high dose vitamin E supplementation for prevention of DNA-adduct formation during occupational exposure to PAHs...
  35. GWAS in Fibrosing Interstitial Lung Disease
    DAVID ALBERT SCHWARTZ; Fiscal Year: 2013
    ..IPF is also associated with exposure to metal or wood dust. Occupational exposure to asbestos can cause fILD that is indistinguishable from the histology of IPF (usual interstitial ..
  36. Soft Tissue Compression Risk in Rotator Cuff Disease Development
    PAULA MARIE LUDEWIG; Fiscal Year: 2013
    ..up to 50% prevalence rates across several populations including persons with spinal cord injury, stroke, occupational exposure to repetitive overhead work, and athletes with repetitive overhead motion exposure...
  37. Air Pollution and Parkinson's in the Danish PASIDA Study
    Beate R Ritz; Fiscal Year: 2013
    ..population controls for whom we have available genotyping information, livelong behavioral risk factor and occupational exposure data from interviews, and additionally data extracted from National Danish hospital and outpatient clinic ..
  38. Targeted liposomal radiotherapy of malignant mesothelioma
    Jiang He; Fiscal Year: 2011
    Mesothelioma, a malignancy associated with occupational exposure to asbestos is a devastating disease without attractive therapies...
  39. Innovative Device to Improve Safety of Preparing and Administering Chemotherapy
    Prasad Sunkara; Fiscal Year: 2013
    ..Long-term occupational exposure to these highly toxic drugs presents serious health risks (e.g...
  40. Polycyclic Aromatic Hydrocarbons And Male Reproductive Health
    HUEIWANG ANNA COOK JENG; Fiscal Year: 2010
    ..The long term goals of the project are: i) to develop field data collection methods to monitor human occupational exposure to PAHs;ii) to evaluate the reproductive altering potential of the exposure;iii) to evaluate the influence ..
  41. Transmission dynamics and spillover of avian influenza under changing agricultura
    Xiangming Xiao; Fiscal Year: 2013
    ..quantify the spillover risk of avian influenzaat the human - poultry - wild bird interface, and evaluate occupational exposure risk of workers in poultry and pig farms;and (3) to assess the effectiveness of various scenarios and ..
  42. Epidemiology of rural MRSA: is livestock contact a risk factor?
    Margaret L Chorazy; Fiscal Year: 2012
    ..Our central hypothesis is that individuals working with livestock will be at risk of occupational exposure to MRSA, and that livestock-associated strains will also be causing symptomatic infections...
  43. Occupational Exposure to PM2.5 and Cardiovascular Disease(CVD)
    MARK RICHARD CULLEN; Fiscal Year: 2013
    ....
  44. A 3D mini-testis model for reproductive toxicity testing
    Xiaozhong Yu; Fiscal Year: 2013
    A 3D mini-testis model for reproductive toxicity testing Project Summary Occupational exposure to reproductive toxicants occurs via inhalation, skin absorption, or ingestion...
  45. PROTECTION AGAINST ORGANOPHOSPHATE NEUROTOXINS BY TOBACCO CEMBRANOIDS
    P A Ferchmin; Fiscal Year: 2010
    ..The risk of OPs exposure is not restricted to war scenario or terrorist attacks but includes industrial leaks of insecticides, accidental poisonings and chronic occupational exposure.
  46. Identification of Functional Targets for Asbestos Induced Autoantibodies
    JEAN COOPER PFAU; Fiscal Year: 2012
    ..is unique in exploring a specific set of autoantibodies that are induced by a toxic environmental and occupational exposure: asbestos...
  47. Pesticides and Parkinson's Disease
    Zhengui Xia; Fiscal Year: 2012
    ..not been defined, epidemiological studies have indicated a correlation between increased risk for PD and occupational exposure to pesticides including paraquat, a widely used herbicide...
  48. DJ-1 in Astrocyte-Mediated Neuroprotection Against Complex I Inhibitors
    J Timothy Greenamyre; Fiscal Year: 2013
    ..One recent study implicated occupational exposure to rotenone...
  49. DNA methylation differences between identical twins
    Thomas Mack; Fiscal Year: 2009
    ..sets of identical twins least likely to have been exposed to environmental toxins, based on residence, occupational exposure, and diet, in order to measure the age-specific levels of DNA methylation, and the degree to which those ..
  50. Community Structure and the Epidemiology of Hantavirus in Southern Chile
    Claudia Munoz-Zanzi; Fiscal Year: 2013
    ..As a rodent-borne infection, transmission has been associated with occupational exposure, visiting rural areas, and domestic activities...
  51. Dietary and Environmental Exposure to Cadmium and the Risk of Endometrial Cancer
    Rudolph P Rull; Fiscal Year: 2012
    ..Major sources of non-occupational exposure to Cd include cigarette smoke, diet, and inhalation of ambient air contaminated by industrial processes ..
  52. Exposure To Polycyclic Aromatic Hydrocarbons And Male Sperm Quality
    HUEIWANG ANNA COOK JENG; Fiscal Year: 2010
    ..PUBLIC HEALTH RELEVANCE: The longitudinal study aims to assess alteration of male sperm quality and DNA oxidative effects caused by occupational exposure to PAHs.
  53. Target Organ DNA Damage in Coke Oven Workers
    Glenn Talaska; Fiscal Year: 2010
    ..These data will be useful to establish and occupational exposure guidance value that will protect the health of these and other workers.
  54. Assessing Workplace Phthalate Exposures Among Massage Therapy Students
    VICTORIA PAK; Fiscal Year: 2010
    ..The specific aims for the proposed study are:1) To determine the extent of occupational exposure of massage therapist students to phthalates in the work setting;2)To determine the levels of the urinary ..
  55. A Pooled Longitudinal Analysis of Workplace Carpal Tunnel Syndrome
    David M Rempel; Fiscal Year: 2012
    ..proposed study will pool the data from these prospective studies to create a large database (N = 3573) of occupational exposure, demographic, covariate and outcome measures across a range of occupations and industries...
  56. Compact, wearable monitor for continuous detection of nitrogen dioxide in mines
    TIMOTHY GEORGE BURLAND; Fiscal Year: 2013
    ..applicant): Over 139 million people, across a broad spectrum of industries in the US, work under threat of occupational exposure to hazardous chemicals...
  57. Community/Worker Exposures to Pathogens from Industrial Food Animal Production
    Ellen K Silbergeld; Fiscal Year: 2012
    ..in workers and communities in IFAP areas, (b) what are the workplace factors associated with risks of occupational exposure;(c) what are the pathways by which occupational exposures affect community health, including social ..
  58. Occupational exposure and the developmental-basis of AD
    NASSER HUSSEIN ZAWIA; Fiscal Year: 2012
    ..We further would like to examine the mechanisms associated with sensitization of animals to disease by early life exposure and how such processes respond in the event of re-exposure during adulthood. ..
  59. North Carolina Occupational Safety and Health Education and Research Center
    BONNIE M ROGERS; Fiscal Year: 2013
    ..In addition, specialized training in Occupational Epidemiology is available. An allied program in Occupational Exposure Science, replacing the former Industrial Hygiene program is proposed...
  60. Cohort analysis methods for occupational cancer studies
    David B Richardson; Fiscal Year: 2012
    ..develop a readily-implementable approach for fitting structural nested models that provide estimates of occupational exposure-cancer associations that are not biased by the healthy worker survivor effect...
  61. Genome-Wide Association Analysis of Bladder Cancer
    Xifeng Wu; Fiscal Year: 2012
    ..PUBLIC HEALTH RELEVANCE Bladder cancer (BC) is a disease mainly caused by smoking and occupational exposure. However, only a small percentage of exposed individuals develop BC...
  62. Characterization of manganese exposure biomarkers among welder apprentices
    Noah S Seixas; Fiscal Year: 2012
    ..PUBLIC HEALTH RELEVANCE: Although there is evidence that occupational exposure to inhaled manganese results in adverse health effects, biomarkers of exposure to manganese are poorly ..
  63. Risk Factors for Crashes in a Retrospective Cohort Study of Commercial Truck Driv
    MATTHEW STEVEN THIESE; Fiscal Year: 2013
    ..data sets, the Federal Motor Carrier Safety Administration (FMCSA) crash data set, JB Hunt Transport occupational exposure data, and the Road Ready data set of 119,670 Commercial Driver Medical Exams (CDME)...
  64. Lung disease due to chronic endotoxin exposure in mouse and human models
    PEGGY SUE LAI; Fiscal Year: 2013
    ..Endotoxin is a ubiquitous and poorly recognized environmental and occupational exposure that may cause non-tobacco related COPD...
  65. SUPERFUND TOXIC SUBSTANCES--EXPOSURE AND DISEASE
    Karl Kelsey; Fiscal Year: 2006
    ..biphenyls (PCBs) and related compounds; cardio-respiratory health is being evaluated in relation to occupational exposure to fuel oil ash, which contains a high level of vanadium and other metals; the occurrence of cancer and ..
  66. CARCINOGENICITY OF 2-NITROPROPANE--A PROBABLE MECHANISM
    Emerich Fiala; Fiscal Year: 2000
    ..The World Health Organization estimates that approximately 4000 U.S. workers may have had significant occupational exposure to this chemical...
  67. Antibiofilm tubing to reduce occupational exposure to biohazards in dentistry
    Yuyu Sun; Fiscal Year: 2009
    ..rechargeable antibiofilm tubing to control the formation of dental unit waterline biofilms so as to reduce occupational exposure of DHCP to the biohazards...
  68. MENSTRUAL FUNCTION AND PHYSICAL AND MENTAL JOB STRESS
    Maureen Hatch; Fiscal Year: 1993
    ..Stress i s pervasive occupational exposure and one that potentially can be prevented or reduced...
  69. Innovations to Inform Occupational Disease Etiology Using Biomonitoring Methods
    JO ANNA SHIMEK; Fiscal Year: 2009
    ..By comparing our list to the National Occupational Exposure Survey (NOES) completed by the National Institute for Occupational Safety and Health (NIOSH) we have ..
  70. Mechanism and Treatment of Manganese Toxicity
    JEROME ALLAN ROTH; Fiscal Year: 2010
    Manganese (Mn) intoxication, a syndrome known as manganism, is most often associated with prolonged occupational exposure, although individuals with cirrhosis of the liver and related hepatic dysfunction display many of the behavioral ..
  71. Biomarkers of Formaldehyde Exposure and Toxicity
    Luoping Zhang; Fiscal Year: 2010
    ..concluded that there is "strong but not sufficient evidence for a causal association between leukemia and occupational exposure to formaldehyde"...
  72. DDT, Endocrine Disruption and Reproductive Outcomes
    Xiaobin Wang; Fiscal Year: 2003
    ..use of medications, sexual intercourse, contraceptive use, active and passive smoking, alcohol use, and occupational exposure; (3) clinical data on reproductive outcomes, including menstrual disturbances, time to conception, SAB, ..
  73. RESPIRATOR EFFICACY VERSUS TUBERCULOSIS AEROSOLS
    John Koerner; Fiscal Year: 2000
    The ultimate goal of this research is to protect health-care and corrections workers from occupational exposure to Mycobacterium tuberculosis by defining the performance of respiratory protection with respect to mycobacterium aerosols...
  74. HEMATOLYMPHOPOIETIC MALIGNANCIES IN ITALY
    Paolo Vineis; Fiscal Year: 1993
    ..exposure to herbicides (including phenoxyacids) in agricultural areas; b) there is also considerable extra-occupational exposure to solvents and pesticides; c) competent groups of hematologists exist in several towns, using advanced ..
  75. QUANTIFICATION OF SKIN ACRYLATE ADDUCTS
    Leena Nylander French; Fiscal Year: 2000
    ..determine chemical specific skin deposition and the dose required to induce adverse dermal effects under occupational exposure conditions...
  76. DENTAL AMALGAMS AND NEUROPSYCHOLOGICAL FUNCTION
    Pam Factor Litvak; Fiscal Year: 1999
    ..b>Occupational exposure to mercury vapor is associated with increases in the prevalence of tremor, peripheral neuropathy, ..
  77. NEW METHODS FOR EVAL OF ORGANIC DUST AEROSOLS
    Stephen Reynolds; Fiscal Year: 2006
    ..measuring inhalable particulates, endotoxins, and glucans/ergosterols that can be used to help establish occupational exposure guidelines for complex organic dusts in swine, poultry, and dairy environments, and to evaluate and ..
  78. Race-Specific Occupational Risk Factors for Cancer
    NATHANIEL BRIGGS; Fiscal Year: 2004
    ..In an analysis using dichotomous occupational exposure data from the SCS, we identified striking increases in risk of NHL, HD, and STS among Black men exposed to ..
  79. RADON, BRONCHIAL MORPHOMETRY, AND OCCUPATIONAL HEALTH
    David Brenner; Fiscal Year: 1993
    The hazards of occupational exposure to radon daughters relative to environmental exposure is significant both for occupational and environmental health...
  80. Repiratory Health and Community Asbestos Exposure
    Bruce Alexander; Fiscal Year: 2007
    ..The proposed research will focus on non-occupational exposure in the community. The following hypotheses will be addressed in this research. 1...
  81. Comparative In Vivo Biodistribution of Characterized Manufactured Nanomaterials
    Nancy A Monteiro Riviere; Fiscal Year: 2010
    ..need to define in vivo disposition of manufactured carbon nanomaterials (MNM) where environmental and/or occupational exposure can occur, as well as assess if in vitro assays and physicochemical properties predict in vivo disposition...
  82. SEMEN AS A BIOMARKER OF EFFECT AMONG LEAD EXPOSED MEN
    Harvey Checkoway; Fiscal Year: 1993
    ..b>Occupational exposure to lead will be the focus of this study...