insect vectors

Summary

Summary: Insects that transmit infective organisms from one host to another or from an inanimate reservoir to an animate host.

Top Publications

  1. doi Pyrethroid resistance in African anopheline mosquitoes: what are the implications for malaria control?
    Hilary Ranson
    Vector Group, Liverpool School of Tropical Medicine, Pembroke Place, Liverpool, UK, L3 5QA
    Trends Parasitol 27:91-8. 2011
  2. pmc Genome sequence of Aedes aegypti, a major arbovirus vector
    Vishvanath Nene
    Institute for Genomic Research, 9712 Medical Center Drive, Rockville, MD 20850, USA
    Science 316:1718-23. 2007
  3. doi Successful establishment of Wolbachia in Aedes populations to suppress dengue transmission
    A A Hoffmann
    Bio21 Institute, Department of Genetics, The University of Melbourne, Victoria 3010, Australia
    Nature 476:454-7. 2011
  4. pmc A single mutation in chikungunya virus affects vector specificity and epidemic potential
    Konstantin A Tsetsarkin
    Department of Pathology, University of Texas Medical Branch, Galveston, Texas, United States of America
    PLoS Pathog 3:e201. 2007
  5. pmc Increased proportions of outdoor feeding among residual malaria vector populations following increased use of insecticide-treated nets in rural Tanzania
    Tanya L Russell
    Ifakara Health Institute, Biomedical and Environmental Thematic Group, Ifakara, Tanzania
    Malar J 10:80. 2011
  6. pmc Species shifts in the Anopheles gambiae complex: do LLINs successfully control Anopheles arabiensis?
    Jovin Kitau
    Kilimanjaro Christian Medical College, Tumaini University, Moshi, Tanzania
    PLoS ONE 7:e31481. 2012
  7. doi Global spread and persistence of dengue
    Jennifer L Kyle
    Division of Infectious Diseases, School of Public Health, and Graduate Group in Microbiology, University of California, Berkeley, California 94720 7354, USA
    Annu Rev Microbiol 62:71-92. 2008
  8. pmc Anopheles gambiae: historical population decline associated with regional distribution of insecticide-treated bed nets in western Nyanza Province, Kenya
    M Nabie Bayoh
    Department of Microbiology and Molecular Genetics, Michigan State University, East Lansing, MI, 48824, USA
    Malar J 9:62. 2010
  9. pmc Impact of daily temperature fluctuations on dengue virus transmission by Aedes aegypti
    Louis Lambrechts
    Department of Virology, Institut Pasteur, 75724 Paris Cedex 15, France
    Proc Natl Acad Sci U S A 108:7460-5. 2011
  10. doi Stable introduction of a life-shortening Wolbachia infection into the mosquito Aedes aegypti
    Conor J McMeniman
    School of Integrative Biology, University of Queensland, Brisbane 4072, Australia
    Science 323:141-4. 2009

Research Grants

Detail Information

Publications332 found, 100 shown here

  1. doi Pyrethroid resistance in African anopheline mosquitoes: what are the implications for malaria control?
    Hilary Ranson
    Vector Group, Liverpool School of Tropical Medicine, Pembroke Place, Liverpool, UK, L3 5QA
    Trends Parasitol 27:91-8. 2011
    ..As we move into the malaria eradication era, it is vital that the implications of insecticide resistance are understood and strategies to mitigate these effects are implemented...
  2. pmc Genome sequence of Aedes aegypti, a major arbovirus vector
    Vishvanath Nene
    Institute for Genomic Research, 9712 Medical Center Drive, Rockville, MD 20850, USA
    Science 316:1718-23. 2007
    ..An increase in genes encoding odorant binding, cytochrome P450, and cuticle domains relative to An. gambiae suggests that members of these protein families underpin some of the biological differences between the two mosquito species...
  3. doi Successful establishment of Wolbachia in Aedes populations to suppress dengue transmission
    A A Hoffmann
    Bio21 Institute, Department of Genetics, The University of Melbourne, Victoria 3010, Australia
    Nature 476:454-7. 2011
    ..These findings demonstrate that Wolbachia-based strategies can be deployed as a practical approach to dengue suppression with potential for area-wide implementation...
  4. pmc A single mutation in chikungunya virus affects vector specificity and epidemic potential
    Konstantin A Tsetsarkin
    Department of Pathology, University of Texas Medical Branch, Galveston, Texas, United States of America
    PLoS Pathog 3:e201. 2007
    ..Due to the widespread distribution of Ae. albopictus, this mutation increases the potential for CHIKV to permanently extend its range into Europe and the Americas...
  5. pmc Increased proportions of outdoor feeding among residual malaria vector populations following increased use of insecticide-treated nets in rural Tanzania
    Tanya L Russell
    Ifakara Health Institute, Biomedical and Environmental Thematic Group, Ifakara, Tanzania
    Malar J 10:80. 2011
    ..In the surveyed area of rural southern Tanzania, bed net use steadily increased over the last decade, reducing malaria transmission intensity by 94%...
  6. pmc Species shifts in the Anopheles gambiae complex: do LLINs successfully control Anopheles arabiensis?
    Jovin Kitau
    Kilimanjaro Christian Medical College, Tumaini University, Moshi, Tanzania
    PLoS ONE 7:e31481. 2012
    ..Shifts in malaria vector species ratio have coincided with the scale-up suggesting that some species are being controlled by ITNs/LLINs better than others...
  7. doi Global spread and persistence of dengue
    Jennifer L Kyle
    Division of Infectious Diseases, School of Public Health, and Graduate Group in Microbiology, University of California, Berkeley, California 94720 7354, USA
    Annu Rev Microbiol 62:71-92. 2008
    ..What is known, as well as gaps in knowledge, is emphasized in light of future prospects for control and prevention of this pandemic disease...
  8. pmc Anopheles gambiae: historical population decline associated with regional distribution of insecticide-treated bed nets in western Nyanza Province, Kenya
    M Nabie Bayoh
    Department of Microbiology and Molecular Genetics, Michigan State University, East Lansing, MI, 48824, USA
    Malar J 9:62. 2010
    ..l.) species complex, namely A. gambiae sensu stricto (s.s.) and Anopheles arabiensis. Historically, the former species was proportionately dominant in indoor resting collections of females...
  9. pmc Impact of daily temperature fluctuations on dengue virus transmission by Aedes aegypti
    Louis Lambrechts
    Department of Virology, Institut Pasteur, 75724 Paris Cedex 15, France
    Proc Natl Acad Sci U S A 108:7460-5. 2011
    ..Our findings reveal the importance of considering short-term temperature variations when studying DENV transmission dynamics...
  10. doi Stable introduction of a life-shortening Wolbachia infection into the mosquito Aedes aegypti
    Conor J McMeniman
    School of Integrative Biology, University of Queensland, Brisbane 4072, Australia
    Science 323:141-4. 2009
    ..Our data suggest that targeting mosquito age with inherited Wolbachia infections may be a viable strategy to reduce the transmission of pathogens such as dengue viruses...
  11. ncbi Critical review of the vector status of Aedes albopictus
    N G Gratz
    Med Vet Entomol 18:215-27. 2004
    ..albopictus in countries endemic for dengue and other arboviruses (e.g. Chikungunya, EEE, Ross River, WNV, LaCrosse and other California group viruses), for which it would be competent and ecologically suited to serve as a bridge vector...
  12. ncbi Indoor residual spraying for preventing malaria
    Bianca Pluess
    Public Health and Epidemiology, Swiss Tropical and Public Health Institute, Basel, Switzerland, 4002
    Cochrane Database Syst Rev 4:CD006657. 2010
    ..Some limited data suggest that ITN give better protection than IRS in unstable areas, but more trials are needed to compare the effects of ITNs with IRS, as well as to quantify their combined effects...
  13. pmc The endosymbiotic bacterium Wolbachia induces resistance to dengue virus in Aedes aegypti
    Guowu Bian
    Department of Entomology and Genetics Program, Michigan State University, East Lansing, Michigan, United States of America
    PLoS Pathog 6:e1000833. 2010
    ..These results underscore the potential usefulness of Wolbachia-based control strategies for population replacement...
  14. pmc Implication of the mosquito midgut microbiota in the defense against malaria parasites
    Yuemei Dong
    W Harry Feinstone Department of Molecular Microbiology and Immunology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, United States of America
    PLoS Pathog 5:e1000423. 2009
    ..We show that the microbiota can modulate the anti-Plasmodium effects of some immune genes. In sum, the microbiota plays an essential role in modulating the mosquito's capacity to sustain Plasmodium infection...
  15. pmc Immune activation by life-shortening Wolbachia and reduced filarial competence in mosquitoes
    Zakaria Kambris
    Peter Medawar Building for Pathogen Research and Department of Zoology, University of Oxford, South Parks Road, Oxford OX1 3PS, UK
    Science 326:134-6. 2009
    ..The cost of constitutive immune up-regulation may contribute to the life-shortening phenotype...
  16. pmc A cryptic subgroup of Anopheles gambiae is highly susceptible to human malaria parasites
    Michelle M Riehle
    Institut Pasteur, Unit of Insect Vector Genetics and Genomics, Department of Parasitology and Mycology, 28 rue du Docteur Roux, Paris 75015, France
    Science 331:596-8. 2011
    ..These findings might have implications for the epidemiology of malaria transmission and control...
  17. pmc Integrated malaria vector control with microbial larvicides and insecticide-treated nets in western Kenya: a controlled trial
    Ulrike Fillinger
    Disease Control and Vector Biology Unit, London School of Hygiene and Tropical Medicine, London, England
    Bull World Health Organ 87:655-65. 2009
    ....
  18. pmc A synthetic homing endonuclease-based gene drive system in the human malaria mosquito
    Nikolai Windbichler
    Imperial College London, Department of Life Sciences, South Kensington Campus, London, SW7 2AZ, UK
    Nature 473:212-5. 2011
    ..Our results also show in principle how sequence-specific genetic drive elements like HEGs could be used to take the step from the genetic engineering of individuals to the genetic engineering of populations...
  19. pmc Immunity to a salivary protein of a sand fly vector protects against the fatal outcome of visceral leishmaniasis in a hamster model
    Regis Gomes
    Centro de Pesquisas Goncalo Moniz, Fundacao Oswaldo Cruz, CEP 40296 710 Salvador, Brazil
    Proc Natl Acad Sci U S A 105:7845-50. 2008
    ....
  20. ncbi Mosquito behavior and vector control
    Helen Pates
    London School of Hygiene and Tropical Medicine, London WC1E 7HT, United Kingdom
    Annu Rev Entomol 50:53-70. 2005
    ..Prospects for genetic control by sterile males or genes rendering mosquitoes harmless to humans will depend on competitive mating behavior. These methods are hampered by the immigration of monogamous, already-mated females...
  21. ncbi A global index representing the stability of malaria transmission
    Anthony Kiszewski
    Harvard School of Public Health, Boston, Massachusetts 02115, USA
    Am J Trop Med Hyg 70:486-98. 2004
    ....
  22. pmc Odorant reception in the malaria mosquito Anopheles gambiae
    Allison F Carey
    Department of Molecular, Cellular and Developmental Biology, Yale University, New Haven, Connecticut 06520, USA
    Nature 464:66-71. 2010
    ..Our analysis of the Anopheles gambiae repertoire identifies receptors that may be useful targets for controlling the transmission of malaria...
  23. pmc An evolutionary conserved function of the JAK-STAT pathway in anti-dengue defense
    Jayme A Souza-Neto
    W Harry Feinstone Department of Molecular Microbiology and Immunology, Bloomberg School of Public Health, The Johns Hopkins University, 615 North Wolfe Street E4209, Baltimore, MD 21205, USA
    Proc Natl Acad Sci U S A 106:17841-6. 2009
    ..Our data suggest that the JAK-STAT pathway is part of the A. aegypti mosquito's anti-dengue defense and may act independently of the Toll pathway and the RNAi-mediated antiviral defenses...
  24. pmc Distribution of knock-down resistance mutations in Anopheles gambiae molecular forms in west and west-central Africa
    Federica Santolamazza
    Istituto Pasteur Fondazione Cenci Bolognetti, Universita La Sapienza, Rome, Italy
    Malar J 7:74. 2008
    ..In M-form populations surveyed to date, only the L1014F mutation has been found, although less widespread and at lower frequencies than in sympatric S-form populations...
  25. ncbi The Innovative Vector Control Consortium: improved control of mosquito-borne diseases
    Janet Hemingway
    Liverpool School of Tropical Medicine, Pembroke Place, Liverpool, UK, L3 5QA
    Trends Parasitol 22:308-12. 2006
    ....
  26. pmc Warmer temperatures reduce the vectorial capacity of malaria mosquitoes
    Krijn P Paaijmans
    Center for Infectious Disease Dynamics, Pennsylvania State University, University Park, PA 16802, USA
    Biol Lett 8:465-8. 2012
    ..These results highlight the need to understand the interactive effects of environmental temperature on multiple host-disease life-history traits and challenge the assumptions of many current disease models that ignore this complexity...
  27. pmc Spread of the tiger: global risk of invasion by the mosquito Aedes albopictus
    Mark Q Benedict
    Centers for Disease Control and Prevention, Atlanta, Georgia 30341, USA
    Vector Borne Zoonotic Dis 7:76-85. 2007
    ..Methods used here have potential for predicting risks of future invasions of vectors or pathogens...
  28. pmc Caspar controls resistance to Plasmodium falciparum in diverse anopheline species
    Lindsey S Garver
    W Harry Feinstone Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, United States of America
    PLoS Pathog 5:e1000335. 2009
    ..These findings have implications for malaria control since broad-spectrum immune activation in diverse anopheline species offers a viable and strategic approach to develop novel malaria control methods worldwide...
  29. doi Aedes albopictus, an arbovirus vector: from the darkness to the light
    C Paupy
    Institut de Recherche pour le Developpement, UR016, BP 1857 Yaoundé, Cameroon
    Microbes Infect 11:1177-85. 2009
    ..Finally, we report conventional and innovative ways to control A. albopictus...
  30. ncbi Impact of permethrin-treated bed nets on entomologic indices in an area of intense year-round malaria transmission
    John E Gimnig
    Division of Parasitic Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30341, USA
    Am J Trop Med Hyg 68:16-22. 2003
    ..These results indicate that ITNs are optimally effective if used every night and if permethrin is reapplied at least biannually...
  31. pmc Development of a new version of the Liverpool Malaria Model. I. Refining the parameter settings and mathematical formulation of basic processes based on a literature review
    Volker Ermert
    Institute of Geophysics and Meteorology, University of Cologne, Cologne, Germany
    Malar J 10:35. 2011
    ..In this study, the parameter settings of the LMM are refined and a new mathematical formulation of key processes related to the growth and size of the vector population are developed...
  32. pmc Spatial evaluation and modeling of Dengue seroprevalence and vector density in Rio de Janeiro, Brazil
    Nildimar Alves Honorio
    Laboratório de Transmissores de Hematozoários, Instituto Oswaldo Cruz, FIOCRUZ, Rio de Janeiro, Brasil
    PLoS Negl Trop Dis 3:e545. 2009
    ..We analyzed individual and spatial factors associated with seroprevalence using Generalized Additive Model (GAM)...
  33. pmc Eco-bio-social determinants of dengue vector breeding: a multicountry study in urban and periurban Asia
    Natarajan Arunachalam
    Centre for Research in Medical Entomology, Indian Council of Medical Research, Madurai, TN, India
    Bull World Health Organ 88:173-84. 2010
    ....
  34. pmc Integrated vector management for malaria control
    John C Beier
    Department of Epidemiology and Public Health, Miller School of Medicine, and the Abess Center for Ecosystem Science and Policy, University of Miami, South Campus, Miami, FL 33177, USA
    Malar J 7:S4. 2008
    ..This review provides an overview of how IVM programmes are being implemented, and provides recommendations for further development of IVM to meet the goals of national malaria control programmes in Africa...
  35. ncbi Chikungunya, an epidemic arbovirosis
    Gilles Pialoux
    Hopital Tenon, Service des Maladies Infectieuses et Tropicales, Paris, France
    Lancet Infect Dis 7:319-27. 2007
    ..Plausible explanations include increased tourism, chikungunya virus introduction into a naive population, and viral mutation...
  36. pmc The multiplicity of malaria transmission: a review of entomological inoculation rate measurements and methods across sub-Saharan Africa
    Louise A Kelly-Hope
    Vector Group, Liverpool School of Tropical Medicine, Liverpool, UK
    Malar J 8:19. 2009
    ....
  37. pmc Yersinia pestis--etiologic agent of plague
    R D Perry
    Department of Microbiology and Immunology, University of Kentucky, Lexington 40536, USA
    Clin Microbiol Rev 10:35-66. 1997
    ..These areas of research have provide new insights into the host-parasite relationship. This review will update our present understanding of the history, etiology, epidemiology, clinical aspects, and public health issues of plague...
  38. pmc Dengue virus type 2: replication and tropisms in orally infected Aedes aegypti mosquitoes
    Ma Isabel Salazar
    Arthropod Borne and Infectious Diseases Laboratory, Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, Colorado 80523 1692, USA
    BMC Microbiol 7:9. 2007
    ..Here we document the virogenesis of DENV-2 in newly-colonized Aedes aegypti mosquitoes from Chetumal, Mexico in order to understand better the effect of vector-virus interactions on dengue transmission...
  39. pmc Transmission of Leishmania metacyclic promastigotes by phlebotomine sand flies
    Paul A Bates
    Liverpool School of Tropical Medicine, Pembroke Place, Liverpool L3 5QA, UK
    Int J Parasitol 37:1097-106. 2007
    ..Differences in the transmission mechanisms employed by parasites in the three subgenera, Leishmania, Viannia and Sauroleishmania are also addressed...
  40. pmc Local adaptation and vector-mediated population structure in Plasmodium vivax malaria
    Deirdre A Joy
    Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA
    Mol Biol Evol 25:1245-52. 2008
    ....
  41. doi Insect vector interactions with persistently transmitted viruses
    Saskia A Hogenhout
    Department of Disease and Stress Biology, John Innes Centre, Norwich, NR4 7UH, United Kingdom
    Annu Rev Phytopathol 46:327-59. 2008
    ..The movement and/or replication of the viruses in the insect vectors require specific interactions between virus and vector components...
  42. ncbi Climate change and highland malaria: fresh air for a hot debate
    Luis Fernando Chaves
    Department of Environmental Studies, Emory University, Atlanta, GA 30322, USA
    Q Rev Biol 85:27-55. 2010
    ....
  43. ncbi A global perspective on the epidemiology of West Nile virus
    Laura D Kramer
    The Arbovirus Laboratories, Wadsworth Center, New York State Department of Health, Slingerlands, NY 12159, USA
    Annu Rev Entomol 53:61-81. 2008
    ..Vector control strategies, vaccines, and antivirals, which now must be considered on a global scale, are also discussed...
  44. pmc Insecticide resistance and the future of malaria control in Zambia
    Emmanuel Chanda
    Ministry of Health, National Malaria Control Centre, Lusaka, Zambia
    PLoS ONE 6:e24336. 2011
    ..This manuscript reports on the monitoring and evaluation of these activities and the potential impact of emerging insecticide resistance on disease transmission...
  45. pmc Understanding the link between malaria risk and climate
    Krijn P Paaijmans
    Center for Infectious Disease Dynamics, Department of Entomology, Chemical Ecology Laboratory, Pennsylvania State University, University Park, PA 16802, USA
    Proc Natl Acad Sci U S A 106:13844-9. 2009
    ..Such effects of short-term temperature fluctuations have not previously been considered but are central to understanding current malaria transmission and the consequences of climate change...
  46. pmc Sterile-insect methods for control of mosquito-borne diseases: an analysis
    Luke Alphey
    Oxitec Limited, Oxford, United Kingdom
    Vector Borne Zoonotic Dis 10:295-311. 2010
    ..This article attempts to address these concerns and indicate where sterile-insect methods are likely to be useful for vector control...
  47. ncbi Influence of temperature on immature development, survival, longevity, fecundity, and gonotrophic cycles of Aedes albopictus, vector of chikungunya and dengue in the Indian Ocean
    H Delatte
    Research Unit 016, Institut de recherche pour le developpement IRD, 7 chemin de l IRAT, 97410 Saint Pierre, La Reunion, France
    J Med Entomol 46:33-41. 2009
    ..5 d). Those results are according to the field repartition of this species in La Réunion, allowing Ae. albopictus survival at a large range of temperatures...
  48. pmc Modeling the effects of weather and climate change on malaria transmission
    Paul Edward Parham
    Department of Infectious Disease Epidemiology, Grantham Institute for Climate Change, Imperial College London, London, United Kingdom
    Environ Health Perspect 118:620-6. 2010
    ....
  49. pmc Exploiting the potential of vector control for disease prevention
    H Townson
    Liverpool School of Tropical Medicine, Liverpool, England
    Bull World Health Organ 83:942-7. 2005
    ....
  50. pmc Molecular basis of odor coding in the malaria vector mosquito Anopheles gambiae
    Guirong Wang
    Department of Biological Sciences, Center for Molecular Neuroscience, Institutes of Chemical Biology and Global Health, Vanderbilt University, Nashville, TN 37235, USA
    Proc Natl Acad Sci U S A 107:4418-23. 2010
    ..gambiae that ultimately may aid in fostering the design and development of olfactory-based strategies for reducing the transmission of malaria and other mosquito-borne diseases...
  51. pmc Vector-virus mutualism accelerates population increase of an invasive whitefly
    Min Jiu
    Institute of Insect Sciences, Zhejiang University, Hangzhou, China
    PLoS ONE 2:e182. 2007
    ....
  52. ncbi Anopheles gambiae s.s. breeding in polluted water bodies in urban Lagos, southwestern Nigeria
    T S Awolola
    Public Health Division, Nigerian Institute of Medical Research, Yaba, Lagos, Nigeria
    J Vector Borne Dis 44:241-4. 2007
    ..Urban malaria is on the rise in Nigeria due to rapid industrialisation and developmental activities. A study was undertaken in Lagos, Nigeria to study the Anopheles breeding in polluted water bodies...
  53. ncbi Evaluation of the antibody response to Anopheles salivary antigens as a potential marker of risk of malaria
    Franck Remoue
    Institut de recherche pour le developpement IRD, UR24 Epidémiologie et Prévention Unit, Centre IRD de Hann, BP 1386, Dakar, Senegal
    Trans R Soc Trop Med Hyg 100:363-70. 2006
    ..These results suggest that evaluation of antisalivary Ab responses could be a useful approach for identifying a marker for the risk of malaria transmission...
  54. pmc Defining challenges and proposing solutions for control of the virus vector Aedes aegypti
    Amy C Morrison
    Department of Entomology, University of California, Davis, Davis, California, United States of America
    PLoS Med 5:e68. 2008
  55. pmc The entomological inoculation rate and Plasmodium falciparum infection in African children
    D L Smith
    Fogarty International Center, National Institutes of Health, Building 16, 16 Center Drive, Bethesda, Maryland 20892, USA
    Nature 438:492-5. 2005
    ..The results have important implications for public health interventions: the success of malaria control will depend heavily on whether efforts are targeted at those who are most at risk of infection...
  56. doi Behavioural aspects influencing plant virus transmission by homopteran insects
    Alberto Fereres
    Departamento de Proteccion Vegetal, Consejo Superior de Investigaciones Cientificas CSIC, Centro de Ciencias Medioambientales, Instituto de Ciencias Agrarias, Madrid, Spain
    Virus Res 141:158-68. 2009
    ....
  57. doi SNP genotyping defines complex gene-flow boundaries among African malaria vector mosquitoes
    D E Neafsey
    Broad Institute, Cambridge, MA 02142, USA
    Science 330:514-7. 2010
    ..Complex genomic differentiation among speciating vector mosquito populations implies that tools for genome-wide monitoring of population structure will prove useful for the advancement of malaria eradication...
  58. pmc Induction of a peptide with activity against a broad spectrum of pathogens in the Aedes aegypti salivary gland, following Infection with Dengue Virus
    Natthanej Luplertlop
    Department of Tropical Hygiene, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    PLoS Pathog 7:e1001252. 2011
    ..aegypti, but also emphasizes the broad-spectrum anti-pathogenic activity of the immature, signal peptide-containing form of this peptide...
  59. pmc Development of vegetable farming: a cause of the emergence of insecticide resistance in populations of Anopheles gambiae in urban areas of Benin
    Anges William M Yadouleton
    Centre de Recherche Entomologique de Cotonou, Benin
    Malar J 8:103. 2009
    ..This study aims to assess the rapid expansion of urban agriculture especially, its contribution to the emergence of insecticide resistance in populations of Anopheles gambiae...
  60. doi Mapping the basic reproduction number (R₀) for vector-borne diseases: a case study on bluetongue virus
    N A Hartemink
    Theoretical Epidemiology, Veterinary Medicine, Utrecht, The Netherlands
    Epidemics 1:153-61. 2009
    ....
  61. pmc Human exposure to anopheline mosquitoes occurs primarily indoors, even for users of insecticide-treated nets in Luangwa Valley, South-east Zambia
    Aklilu Seyoum
    Liverpool School of Tropical Medicine, Vector Group, Pembroke Place, Liverpool L3 5QA, UK
    Parasit Vectors 5:101. 2012
    ..We studied the human biting behaviour of the malaria vector Anopheles funestus Giles and the potential malaria vector Anopheles quadriannulatus Theobald in Luangwa valley, south-east Zambia...
  62. ncbi Effect of temperature on the development of the aquatic stages of Anopheles gambiae sensu stricto (Diptera: Culicidae)
    M N Bayoh
    School of Biological and Biomedical Sciences Science Laboratories, University of Durham Durham DH1 3LE UK
    Bull Entomol Res 93:375-81. 2003
    ..gambiae s.s. corresponded closely with the best map of malaria risk currently available for Africa...
  63. pmc Fine-scale variation in vector host use and force of infection drive localized patterns of West Nile virus transmission
    Gabriel L Hamer
    Department of Pathobiological Sciences, University of Wisconsin, Madison, Wisconsin, United States of America
    PLoS ONE 6:e23767. 2011
    ..Rather, robust assessment of local transmission risk should incorporate heterogeneity in vector host feeding and variation in vertebrate reservoir competence at the spatial scale of vector-host interaction...
  64. pmc Chikungunya virus emergence is constrained in Asia by lineage-specific adaptive landscapes
    Konstantin A Tsetsarkin
    Institute for Human Infections and Immunity, Center for Tropical Diseases and Department of Pathology, University of Texas Medical Branch, Galveston, TX 77555, USA
    Proc Natl Acad Sci U S A 108:7872-7. 2011
    ..albopictus-adapted African strains. These results underscore how different adaptive landscapes occupied by closely related viral genotypes can profoundly affect the outcome of viral evolution and disease emergence...
  65. pmc Disentangling vector-borne transmission networks: a universal DNA barcoding method to identify vertebrate hosts from arthropod bloodmeals
    Miguel Alcaide
    Estacion Biologica de Donana CSIC, Isla de la Cartuja, Sevilla, Spain
    PLoS ONE 4:e7092. 2009
    ..Such information is crucial to support the efficient management of initiatives aimed at reducing epidemiologic risks of arthropod vector-borne pathogens, a priority for public health...
  66. pmc Revisiting the basic reproductive number for malaria and its implications for malaria control
    David L Smith
    Fogarty International Center, National Institutes of Health, Bethesda, Maryland, United States of America
    PLoS Biol 5:e42. 2007
    ..Therefore, strategic planning for malaria control should consider R0, the spatial scale of transmission, human population density, and heterogeneous biting...
  67. doi Role of vector control in the global program to eliminate lymphatic filariasis
    Moses J Bockarie
    Centre for Neglected Tropical Diseases, Liverpool School of Tropical Medicine, Pembroke Place, Liverpool L3 5QA, United Kingdom
    Annu Rev Entomol 54:469-87. 2009
    ....
  68. doi Does kdr genotype predict insecticide-resistance phenotype in mosquitoes?
    Martin J Donnelly
    Vector Group, Liverpool School of Tropical Medicine, Liverpool L35QA, UK
    Trends Parasitol 25:213-9. 2009
    ..However, we emphasize that kdr genotype might explain only a portion of heritable variation in resistance and that diagnostic assays to test the importance of other resistance mechanisms in field populations are required...
  69. pmc Immunity to distinct sand fly salivary proteins primes the anti-Leishmania immune response towards protection or exacerbation of disease
    Fabiano Oliveira
    Vector Molecular Biology Unit, Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, Maryland, USA
    PLoS Negl Trop Dis 2:e226. 2008
    ..major infection. Here, we analyze the immune response to distinct salivary proteins from P. papatasi that produced contrasting outcomes of L. major infection...
  70. ncbi Antibody response against saliva antigens of Anopheles gambiae and Aedes aegypti in travellers in tropical Africa
    Eve Orlandi-Pradines
    Unité de recherche en biologie et en épidémiologie parasitaires, Institut de Medecine Tropicale du Service de Sante des Armees, Parc le Pharo, BP 46, 13998 Marseille Armees, France
    Microbes Infect 9:1454-62. 2007
    ..These results suggest that antibody responses to the saliva of mosquitoes could be considered as specific surrogate markers of exposure of travellers to mosquito vectors that transmit arthropod borne infections...
  71. ncbi Association between land cover and habitat productivity of malaria vectors in western Kenyan highlands
    Stephen Munga
    Kenya Medical Research Institute, Kisumu, Kenya
    Am J Trop Med Hyg 74:69-75. 2006
    ..gambiae larvae, and consequently increase the risks of malaria transmission to the human population...
  72. pmc Climate change and mosquito-borne disease
    P Reiter
    Dengue Branch, Division of Vector Borne Infectious Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, U S Department of Health and Human Services, San Juan, Puerto Rico 00920 3860
    Environ Health Perspect 109:141-61. 2001
    ..It is therefore inappropriate to use climate-based models to predict future prevalence...
  73. pmc Human antibody response to Anopheles gambiae saliva: an immuno-epidemiological biomarker to evaluate the efficacy of insecticide-treated nets in malaria vector control
    Papa M Drame
    Institut de recherche pour le developpement IRD, UR024 Epidémiologie et Prévention Unit, Dakar, Senegal
    Am J Trop Med Hyg 83:115-21. 2010
    ..This study represents the first stage in the development of a new indicator to evaluate the efficacy of malaria vector-control strategies, which could apply in other arthropod vector-borne diseases...
  74. doi Ecology and geographical expansion of Japanese encephalitis virus
    Andrew F van den Hurk
    Virology, Queensland Health Forensic and Scientific Services, Archerfield, Queensland 4108, Australia
    Annu Rev Entomol 54:17-35. 2009
    ..This review outlines the ecology of JEV and examines the recent expansion of its geographical range, before assessing its ability to emerge in new regions, using the hypothetical establishment in the United States as a case study...
  75. pmc An experimental hut evaluation of Olyset nets against anopheline mosquitoes after seven years use in Tanzanian villages
    Robert C Malima
    London School of Hygiene and Tropical Medicine, WC1E 7HT, London, UK
    Malar J 7:38. 2008
    ..It has not been determined for how long Olyset nets remain protective against mosquitoes in household use...
  76. pmc Exploring the contributions of bed nets, cattle, insecticides and excitorepellency to malaria control: a deterministic model of mosquito host-seeking behaviour and mortality
    Gerry F Killeen
    Ifakara Health Research and Development Centre, Box 53, Ifakara, Kilombero, Morogoro, United Republic of Tanzania
    Trans R Soc Trop Med Hyg 101:867-80. 2007
    ..As financial support, technology and distribution systems for insecticide-treated nets improve, massive reductions in malaria transmission could be realised...
  77. pmc Leucine-rich repeat protein complex activates mosquito complement in defense against Plasmodium parasites
    Michael Povelones
    Division of Cell and Molecular Biology, Department of Life Sciences, Imperial College London, Exhibition Road, London SW7 2AZ, UK
    Science 324:258-61. 2009
    ..LRIM1 and APL1C are members of a protein family with orthologs in other disease vector mosquitoes and appear to be important effectors in innate mosquito defenses against human pathogens...
  78. pmc Identifying the most productive breeding sites for malaria mosquitoes in The Gambia
    Ulrike Fillinger
    Disease Control and Vector Biology Unit, London School of Hygiene and Tropical Medicine, London, UK
    Malar J 8:62. 2009
    ..This study aimed to determine the characteristics of larval habitats most frequently and most densely populated by anopheline larvae and to estimate the numbers of adults produced in different habitats...
  79. pmc Bluetongue epidemiology in the European Union
    Claude Saegerman
    Department of Infectious and Parasitic Diseases, Epidemiology and Risk Analysis Applied to Veterinary, University of Liege, Liege, Belgium
    Emerg Infect Dis 14:539-44. 2008
    ..This condition increases the risk for reassortment of individual BTV gene segments...
  80. ncbi Identification of aerobic gut bacteria from the kala azar vector, Phlebotomus argentipes: a platform for potential paratransgenic manipulation of sand flies
    Heidi Hillesland
    Department of Internal Medicine, University of New Mexico, Albuquerque, New Mexico 87131, USA
    Am J Trop Med Hyg 79:881-6. 2008
    ..Both organisms are also used extensively in industry. Our results indicate that B. megaterium and B. linens are possible candidates for use in a model of paratransgenesis to prevent transmission of Leishmania...
  81. pmc Comparative fitness assessment of Anopheles stephensi transgenic lines receptive to site-specific integration
    D A Amenya
    Program in Public Health, University of California, Irvine, CA 92697 3900, USA
    Insect Mol Biol 19:263-9. 2010
    ..These transgenic lines are suitable for future site-specific integrations of antiparasite transgenes into the attP sites...
  82. pmc Effective control of dengue vectors with curtains and water container covers treated with insecticide in Mexico and Venezuela: cluster randomised trials
    Axel Kroeger
    Special Programme for Research and Training in Tropical Medicine TDR WHO, World Health Organization, Geneva, Switzerland
    BMJ 332:1247-52. 2006
    ..To measure the impact on the dengue vector population (Aedes aegypti) and disease transmission of window curtains and water container covers treated with insecticide...
  83. pmc Hemocyte differentiation mediates innate immune memory in Anopheles gambiae mosquitoes
    Janneth Rodrigues
    Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, MD 20892, USA
    Science 329:1353-5. 2010
    ..In mosquitoes, differentiation of hemocytes was necessary and sufficient to confer innate immune memory...
  84. pmc Highly focused anopheline breeding sites and malaria transmission in Dakar
    Vanessa Machault
    Unité d entomologie médicale, Equipe 7 Maladies Emergentes et Moustiques, Institut de Medecine Tropicale du Service de Sante des Armees, Allée du Médecin Colonel Jamot, Parc du Pharo, 13262 Marseille cedex 07, France
    Malar J 8:138. 2009
    ....
  85. ncbi Anopheles arabiensis and An. quadriannulatus resistance to DDT in South Africa
    K Hargreaves
    Malaria Control Programme, KwaZulu Natal Department of Health, Jozini, South Africa
    Med Vet Entomol 17:417-22. 2003
    ..funestus Giles, indicates an urgent need to develop a strategy of insecticide resistance management for the malaria control programmes of southern Africa...
  86. pmc Detection of knockdown resistance (kdr) mutations in Anopheles gambiae: a comparison of two new high-throughput assays with existing methods
    Chris Bass
    Department of Biological Chemistry, Rothamsted Research, Harpenden, UK
    Malar J 6:111. 2007
    ..However, there are few reports comparing the performance of these different assays. In this study, two new high-throughput assays were developed and compared with four established techniques...
  87. ncbi Seasonality, blood feeding behavior, and transmission of Plasmodium falciparum by Anopheles arabiensis after an extended drought in southern Zambia
    Rebekah J Kent
    The W Harry Feinstone Department of Molecular Microbiology and Immunology, The Johns Hopkins Malaria Research Institute, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland 21205, USA
    Am J Trop Med Hyg 76:267-74. 2007
    ..923, An. arabiensis was substantially more anthropophilic in our study area than comparable samples of indoor-resting An. arabiensis throughout Africa and was the primary vector responsible for transmission of P. falciparum...
  88. ncbi [Aedes albopictus, vector of chikungunya and dengue viruses in Reunion Island: biology and control]
    H Delatte
    UR 016, IRD, BP 64501, 34394 Montpellier 5, France
    Parasite 15:3-13. 2008
    ..In order to prevent such epidemics, a preventive plan for arboviruses upsurge is ongoing processed. This plan would allow a quicker response to the threat and adapt it according to the virus and its specific vector...
  89. pmc In vivo imaging reveals an essential role for neutrophils in leishmaniasis transmitted by sand flies
    Nathan C Peters
    Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, Bethesda, MD 20892, USA
    Science 321:970-4. 2008
    ..Thus, L.m. appears to have evolved to both evade and exploit the innate host response to sand fly bite in order to establish and promote disease...
  90. pmc A lipophosphoglycan-independent development of Leishmania in permissive sand flies
    Jitka Myskova
    Department of Parasitology, Faculty of Science, Charles University, Vinicna 7, Prague 2, Czech Republic
    Microbes Infect 9:317-24. 2007
    Leishmaniases are serious parasitic diseases the etiological organisms of which are transmitted by insect vectors, phlebotominae sand flies. Two sand fly species, Phlebotomus papatasi and P...
  91. pmc Advantages of larval control for African malaria vectors: low mobility and behavioural responsiveness of immature mosquito stages allow high effective coverage
    Gerry F Killeen
    Department of Tropical Medicine, School of Public Health and Tropical Medicine, Tulane University Health Sciences Centre, 1430 Tulane Avenue, New Orleans, Louisiana 70112, USA
    Malar J 1:8. 2002
    ....
  92. pmc Pyrethroid resistance in Aedes aegypti from Grand Cayman
    Angela F Harris
    The Mosquito Research and Control Unit, Grand Cayman, Cayman Islands, British West Indies
    Am J Trop Med Hyg 83:277-84. 2010
    ..The F1534C mutation was strongly correlated with resistance to DDT and permethrin...
  93. pmc Urbanization, malaria transmission and disease burden in Africa
    Simon I Hay
    TALA Research Group in the Department of Zoology, University of Oxford, South Parks Road, Oxford OX1 3PS, UK
    Nat Rev Microbiol 3:81-90. 2005
    ..We find there were 1,068,505 malaria deaths in Africa in 2000 - a modest 6.7% reduction over previous iterations. The public-health implications of these findings and revised estimates are discussed...
  94. pmc Concurrent chikungunya and dengue virus infections during simultaneous outbreaks, Gabon, 2007
    Eric M Leroy
    Centre International de Recherches Medicales de Franceville, Franceville, Gabon
    Emerg Infect Dis 15:591-3. 2009
    ..Chikungunya or dengue-2 virus infections were identified in 321 patients; 8 patients had documented co-infections. Aedes albopictus was identified as the principal vector for the transmission of both viruses...
  95. pmc Topography and malaria transmission heterogeneity in western Kenya highlands: prospects for focal vector control
    Andrew K Githeko
    Climate and Human Health Research Unit, Centre for Vector Biology and Control Research, Kenya Medical Research Institute, Kisumu, Kenya
    Malar J 5:107. 2006
    ..The aim of this study was to determine the effects of topography on malaria spatial vector distribution and parasite prevalence...
  96. pmc House design modifications reduce indoor resting malaria vector densities in rice irrigation scheme area in western Kenya
    Harrysone Atieli
    Kenya Medical Research Institute, Kisumu, Kenya
    Malar J 8:108. 2009
    ..A randomized-controlled study was, therefore, undertaken to determine the effects of this method of vector control on the density of indoor resting malaria vectors in a rice irrigation scheme area in lowlands of western Kenya...
  97. doi Current epidemiological understanding of citrus Huanglongbing
    Tim R Gottwald
    U S Department of Agriculture, Agricultural Research Service, US Horticultural Research Laboratory, Fort Pierce, Florida, USA tim gottwald ars usda gov
    Annu Rev Phytopathol 48:119-39. 2010
    ..Multiple asymptomatic infections per symptomatic tree, incomplete systemic distribution within trees, and prolonged incubation period make detection difficult and greatly complicate disease control...
  98. pmc Massively parallel pyrosequencing-based transcriptome analyses of small brown planthopper (Laodelphax striatellus), a vector insect transmitting rice stripe virus (RSV)
    Fujie Zhang
    State Key Laboratory of Plant Genomics, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China
    BMC Genomics 11:303. 2010
    ..To investigate its transcriptome and determine the differences between viruliferous and naïve L. striatellus, we employed 454-FLX high-throughput pyrosequencing to generate EST databases of this insect...
  99. pmc Hemolytic C-type lectin CEL-III from sea cucumber expressed in transgenic mosquitoes impairs malaria parasite development
    Shigeto Yoshida
    Division of Medical Zoology, Department of Infection and Immunity, Jichi Medical University, Tochigi, Japan
    PLoS Pathog 3:e192. 2007
    ....
  100. ncbi Nanos (nos) genes of the vector mosquitoes, Anopheles gambiae, Anopheles stephensi and Aedes aegypti
    Eric Calvo
    Department of Molecular Biology and Biochemistry, 3205 McGaugh Hall, University of California, Irvine, CA 92697 3900, USA
    Insect Biochem Mol Biol 35:789-98. 2005
    ..These features make nos genes promising candidates for donating control sequences to modified transposons...
  101. ncbi Insect vectors of Leishmania: distribution, physiology and their control
    Umakant Sharma
    Division of Clinical Microbiology, Department of Laboratory Medicine, All India Institute of Medical Sciences, New Delhi, India
    J Vector Borne Dis 45:255-72. 2008
    ..This review gives an insight into the insect vectors of human leishmaniasis, their geographical distribution, recent taxonomic classification, habitat, and ..

Research Grants74

  1. BIOCHEMISTRY OF PROPHENOL OXIDASE ACTIVATING PROTEINASE
    Haobo Jiang; Fiscal Year: 2003
    ..This research will contribute to our understanding of the biochemical process of pro-phenol oxidase activation, and will generate useful molecular probes for studying similar systems in insect vectors of human diseases.
  2. A Viral Vector for Gene Expression in Insects
    Ranjit Dasgupta; Fiscal Year: 2003
    ..Understanding the physiology of insect vectors, and the molecular interactions between those insects and the pathogens they transmit is critical for ..
  3. The role of sand fly saliva in visceralization of Leishmania parasites.
    Gregory Lanzaro; Fiscal Year: 2007
    ..These findings have had a profound effect on our understanding of the relationship between insect vectors, the parasites they transmit, and the diseases they cause...
  4. The role of sand fly saliva in visceralization of Leishmania parasites
    Gregory Lanzaro; Fiscal Year: 2009
    ..These findings have had a profound effect on our understanding of the relationship between insect vectors, the parasites they transmit, and the diseases they cause...
  5. REGULATION OF DIGESTION IN BLOOD-SUCKING INSECTS
    Michael Wells; Fiscal Year: 1993
    ..Relatively little work using modern biochemical and molecular biological approaches has been done on insect vectors. The ingestion of the blood meal induces many morphological and biochemical changes in the midgut, which are ..
  6. Vector-Borne Disease Control in Urban Environments (RMI)
    John C Beier; Fiscal Year: 2006
    ..and natural disasters all contribute to the development of conditions that modify the natural habitats of insect vectors. These complex problems can best be addressed through interdisciplinary approaches, as history has shown that ..
  7. Lectins in Insect Immunity
    Xiao Qiang Yu; Fiscal Year: 2006
    ..In insect vectors of human diseases, detection and killing of parasites are not highly effective, perhaps because certain ..
  8. Rapid Detection and Identification of Zoonotic Pathogens
    John Dunn; Fiscal Year: 2007
    Zoonotic pathogens including those transmitted by insect vectors are some of the most deadly of all infectious diseases known to mankind...
  9. PROTEINASE SYSTEMS IN INSECT HEMOLYMPH
    Michael Kanost; Fiscal Year: 2006
    ..Such immune responses are likely to affect the outcome of infections of insect vectors with the pathogens and parasites they transmit...
  10. PROTEINASE SYSTEMS IN INSECT HEMOLYMPH
    Michael Kanost; Fiscal Year: 2003
    ..Such immune responses are likely to affect the outcome of infections of insect vectors with the pathogens and parasites they transmit...
  11. Role of the DSC1 family of cation channels in insect neurophysiology and neurotox
    Ke Dong; Fiscal Year: 2009
    Use of insecticides and repellents to control insect vectors is an important strategy for fighting some of the most devastating human diseases, such as malaria...
  12. Role of the DSC1 family of cation channels in insect neurophysiology and neurotox
    Chun Fang Wu; Fiscal Year: 2010
    Use of insecticides and repellents to control insect vectors is an important strategy for fighting some of the most devastating human diseases, such as malaria...
  13. A Novel Virus that Infects & Sterilizes Insect Vectors of Human Disease
    Drion Boucias; Fiscal Year: 2007
    ..and biological data on a novel virus group, the salivary gland hypertrophic viruses (SGHVs), which impacts insect vectors of both human and animal diseases...
  14. ACTIONS OF SEMINAL PROTEINS IN MATED DROSOPHILA FEMALES
    MARIANA FEDERICA WOLFNER; Fiscal Year: 2010
    ..genetics to dissect seminal protein function informs the understanding of human fertility and the control of insect vectors of disease...
  15. INSECT HEME OXYGENASE
    Boris Dunkov; Fiscal Year: 2004
    ..They will provide a tool to study the fate of heme in hematophagous insect vectors of disease, and may lead to the design of novel and effective ways to control insects of medical importance...
  16. SYNTHESIS AND DEGRADATION OF RIBOSOMES IN THE MOSQUITO
    Ann Fallon; Fiscal Year: 2004
    ..undescribed C-terminal similarity to histone H1 protein is shared among two closely related groups of insect vectors. The 5'-flanking sequences of the mosquito rpS6 gene will be compared to those of rpL8 and rpL34, and sites ..
  17. Macrofilaricidal Aminoacyl-tRNA Synthetase Inhibitors
    Michael Kron; Fiscal Year: 2005
    ..provides an infrastructure and model for future infectious disease therapeutics research to combat the full spectrum of bacterial, fungal, unicellular, and multicellular parasites of man, as well as insect vectors of human disease.
  18. SURVIVAL AND EXTINCTION IN RNA VIRUS POPULATIONS
    ISABEL NOVELLA; Fiscal Year: 2003
    ..Specifically, the proposal will address the effect of antibody response and of replication in insect vectors, on virus survival and adaptation.
  19. Nutritional and endocrine control of mosquito egg development.
    Aparna Telang; Fiscal Year: 2007
    ..a deeper understanding of how mosquitoes function in their environment, leading to novel ways of controlling insect vectors of disease. My background in organismal biology, ecology, and biochemistry will help reach this goal...
  20. Molecular Basis of Francisella Virulence and Immunity
    THOMAS KAWULA; Fiscal Year: 2005
    ..numerous transmission mechanisms including inhalation, ingestion, skin contact, mucous membrane contact, and insect vectors. Little is known about the mechanisms of F. tularensis pathogenesis and host resistance. F...