sterilization

..Experiments in Radiation Sterilization. The goal is to determine whether radiation sterilization is able to be used with biological products...

..Gamma radiation has been used for the terminal sterilization and viral inactivation of the biological products...

..This sterilization method can provide a faster, more reliable, more economical sterilizer for in-hospital use and broaden the ..

..dry and wet conditions; 2) the in vitro rate of drug elution from samples; 3) the effect of ethylene oxide sterilization on the drug-nanofiber mat samples; and 4) the in vitro biocompatibility of samples with human ocular epidermal ..

..The initial step reduces the bioburden with the second step in sterilization resulting in "terminal sterilization"...

..The initial step reduces the bioburden with the second step in sterilization resulting in "terminal sterilization"...

..The strategy utilizes a novel type of chemical sterilization called S-59 that results in DNA crosslinks when exposed to UVA radiation...

..other materials used in sensitive medical equipment degrade under the conditions of steam or gamma radiation sterilization. Currently explosive 100% ethylene oxide is being used to sterilize many dialyzers and other sensitive medical ..

..proximity of the prostate, will be radiolucent, nonmagnetic, dielectric, and will provide means for safety and sterilization. For this, the system, including the motors, will be constructed of materials such as plastics, carbon fiber ..

..Normal hospital sterilization procedures do not inactivate prions, leading to the possibility of iatrogenic prion disease...

..b>Sterilization by autoclaving or use of caustic chemicals such as Cidex can be harmful to patients and/or components...

..will address the manufacturing process and its validation, design control, biocompatibility, gamma radiation sterilization validation, package strength and integrity, accelerated aging for regulatory purposes on a prototype basis...

..Only 25-35 percent of CL wearers follow all of their recommended lens care instructions. A new sterilization method is proposed for CLs and lens cases that should improve patient compliance by simplifying their lens ..

..We propose to research and develop a novel, reliable, and affordable technology for effective sterilization of dental handpieces at room temperature...

..As a result of these reports, the manufacturer of the CS-3000 disposable apheresis kits changed their sterilization techniques from predominantly EO exposure to predominantly gamma irradiation...

..polynesiensis mosquitoes infected with Wolbachia bacteria result in the sterilization of female mosquitoes at a field site endemic for filariasis transmission...

..would make mevalonate pathway inhibitors particularly attractive in burn unit or intensive care settings where sterilization of the normal bacterial flora make yeast over growth or colonization by resistant bacteria a common and severe ..

..polynesiensis mosquitoes infected with Wolbachia bacteria result in the sterilization of female mosquitoes at a field site endemic for filariasis transmission...

..Critical to the application is that sterilization processes are essential to the healthcare industry and are required to monitor the effectiveness of equipment ..

..by applicant): We propose to research and develop a novel, reliable, and affordable technology for effective sterilization of Dental Handpieces (DH) at room temperature...

..Once developed, the product can also be expanded for use with other blood product components and other medical sterilization applications such as water sterilization, infected surgical incisions, trauma and burn wounds, etc.

..goal of the investigation to be pursued in Phase II is the development of an appropriate delivery vehicle for lens and lens case sterilization. We will initiate this work during Phase I, and possible approaches are also discussed herein.

..also examine the commercializability of the peptide coating through an exhaustive battery of biocompatibility, sterilization and storage tests...

DESCRIPTION (provided by applicant): In 1907, Indiana implemented the world's first eugenic sterilization law. The upcoming centenary of this act provides an opportune time to evaluate the far-reaching significance of this event...

..of minute amounts of radiolytically controlled formaldehyde (CH2O) precursors; (2) under radiochemical sterilization (RC-S) conditions described in 1, in vitro and in vivo suture properties of PP and PG are not significantly ..

..and implants by providing a higher level of cleanliness and decontamination, while simultaneously providing sterilization. The BRP will determine the effectiveness of dense phase (liquid or compressed gas) carbon dioxide fluid ..

..Notably, nikkomycin Z treatment resulted in sterilization of the murine lesions...

..evidence indicates that EP rates may not be declining; and a number of important risk factors-including tubal sterilization, advanced maternal age and Chlamydia trachomatis and other asymptomatic sexually transmitted infections -have ..

..evidence indicates that EP rates may not be declining; and a number of important risk factors-including tubal sterilization, advanced maternal age and Chlamydia trachomatis and other asymptomatic sexually transmitted infections -have ..

..Notably, nikkomycin Z treatment resulted in sterilization of the murine lesions...

..that they comply with medical safety standards (EN60601-1), biocompatibility (ISO-10993), and validate the sterilization to a sterility assurance level (SAL) of 10-6...

..Notably, nikkomycin Z treatment resulted in sterilization of the murine lesions...

..It has been used for the sterilization and viral inactivation of blood products and elimination of adventitious agents in cell lines...

..destroying pathogens in the case of heat and moisture sensitive materials has led to its wide spread use in sterilization processes...

Description (provided by applicant): Development of novel biomedical sterilization technology is proposed. The method utilizes supercritical C02, which allows for the sterilization of materials that are incompatible with current methods...

..sterility testing, BCR proposes a Phase II validation study of a rapid biological indicator (rBI) for steam sterilization. The study's overall objective is to assemble a database for submitting a premarket 510(k) notification to the ..

..Random Hand Hygiene Prompts will encourage hand washing and hand sterilization in hospitals...

..five main aspects of young adult family formation: entrance into first marriage; rates of contraceptive use, sterilization, and rates of child birth, including both first births and progression to higher parity...

..PUBLIC HEALTH RELEVANCE: Encouraging Hygiene Messages (EHM) will encourage hand washing and hand sterilization in hospitals...

..Studies will also be conducted to establish if the peptide/heparin-coated graft can withstand sterilization with ethylene oxide, the preferred sterilization route for ePTFE...

..Design: Cohort study of consecutively identified patients undergoing laparoscopy for tubal sterilization or as a diagnostic procedure. Setting: Two university-affiliated hospitals...

..Key Words: Endoscope, sterilization, peracids, spores, disinfection, cold sterilants, peroxygen compounds, liquid chemical germicides...

..five main aspects of young adult family formation: entrance into first marriage; rates of contraceptive use, sterilization, and rates of child birth, including both first births and progression to higher parity...

..prep rooms and the quarantine and ABSL3 entrances will be constructed to utilize vapor phase hydrogen peroxide sterilization. Electrical service in animal rooms and the surgical suite will be upgraded...

..We will also initiate biocompatibility, storage and sterilization testing of our prototype vancomycin:metal IFBM to ensure this is a commercializable product concept...

..Ethylene Oxide sterilization processes will be validated during the course of the grant and used to sterilize TMOD devices in preparation ..

..ovarian drilling/wedge resection for fertility and a group of normally cycling women undergoing elective tubal sterilization. Immunohistochemistry, immunoblots and RT-PCR/real time PCR will be used to determine the expression and ..

..7mm with strength of 50 Newtons; 3) an independent laboratory determination of bioburden and ethylene oxide sterilization validation, and toxicology testing...

..is to evaluate and characterize variable frequency microwave (VFM) technology for use in dry bacterial spore sterilization with the ultimate goal of producing a device capable of eliminating microbial/viral/biological toxin based ..

DESCRIPTION (provided by applicant): Funds from this program will be used to purchase two biological sterilization units (autoclaves) for the Center for Laboratory Animal Sciences (CLAS) J1 building at the University of California at ..

..By doing this we can optimize the porous support and overall system for high flux or steam sterilization in combination with wet-out resistance...

..with this goal and will be to (1) use surface phosphonylation, solid-state orientation, and radiochemical sterilization, for optimized preparation of solid-state oriented PEEK, CFR-PEEK composites, and fiber self- reinforced PEEK ..

..are housed in the original part of the ASB and are dependent on the old cage washing facility for NHP cage sterilization and sanitation...

..develop and demonstrate scale-up of the EIROF deposition process and to establish protocols for handling and sterilization of coatings prior to implantation, and 5) to facilitate adoption of EIROF by end-users and device ..

..II. BioTex chemists and engineers will perform studies to optimize a pre-sterilization formulation protocol of sensor by freeze-drying/vacuum-packaging. III...

..II. BioTex chemists and engineers will perform studies to optimize a pre-sterilization formulation protocol of sensor by freeze-drying/vacuum-packaging. III...

..There is a need for the development of effective antiseptic formulations for hand sterilization that rapidly kill of broad spectrum of microbial pathogens and fully address compliance issues associated with ..

..This sensor will enable more rapid and reliable development of sterilization cycles, equipment qualification and continuous monitoring, which will significantly improve sterility ..

..of internal channels and surfaces, improper or inadequate lubrication of moving parts, and repeated steam sterilization. Currently, there is no technology that is capable of delivering standardized effective cleaning and ..

..Within the past decade, polyethylene materials used for THR have undergone major changes in sterilization and formulation, so that a range of sterilization and radiation crosslinking processes are now applied to ..

..Within the past decade, polyethylene materials used for THR have undergone major changes in sterilization and formulation, so that a range of sterilization and radiation crosslinking processes are now applied to ..

..headspace analysis of EO residues, different polymers and medical devices subjected to different numbers of sterilization cycles were examined...

..can be cost-effective if the safety of patients can be assured; however, there is increasing evidence that the sterilization process may not be completely effective...

..It would appear that, using this methodology, there is little risk of a cross-infection hazard occurring with the re-use of previously tried-in and decontaminated molar bands...

..These include beds, mattresses, curtains, bedpans and sphygmomanometers, all of which may be contaminated with micro-organisms (Wilson, 2001)...

..reduce bacterial numbers on endodontic files, and evaluated the effect of biological debris on the subsequent sterilization of files...

OBJECTIVE: To assess the effect of a standard decontamination and sterilization protocol employed during reuse of cardiac electrophysiology (EP) catheters on human immunodeficiency virus (HIV)...

..We describe here two simple, practical cleaning protocols that are effective in removing organic debris from files. Rotary NiTi files can be safely re-used from an infection control perspective...

..tests combined with in-situ and destructive testing to evaluate cleaning efficacy and ethylene oxide sterilization of single-use triple lumen sphinctertomes...

..001). We conclude that protein cross-contamination of the laryngeal mask airway occurs during batch cleaning and autoclaving and recommend that reusable airway devices are cleaned in isolation...

..CONCLUSIONS: The Siqveland matrix band is the most popular among the study group of dental practitioners. Re-use of matrix bands is common. Guidelines for the safe re-use of matrix bands are required...

..with bacteria, yeast and non-enveloped virus showed decimal reduction factors that were equivalent to sterilization. The trays had optimal sealing qualities...

..It is only recently that medical device-associated cleaning, disinfection and sterilization technologies have been investigated and the results of these studies are summarized in this report...

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..The investigation found no evidence of patient-to-patient transmission of HCV among patients attending the practice of a dentist who admitted periodically using unsterilized equipment...

..CONCLUSIONS: A conventional cleaning method is capable of effectively removing biological debris from endodontic files. The efficacy of ultrasonic cleaning was impaired when the files were placed within a perforated container...

..The cleaned instruments are packaged before sterilization to protect them from recontamination until they are opened for use for the next patient...

..AND METHODS: Eighty dentures were fabricated in a standardized procedure and subjected to ethylene oxide sterilization. The dentures were individually inoculated (10(7) cfu/mL) with tryptic soy broth (TSB) media containing one of ..

This study evaluated the suitability of some disinfection and sterilization methods for use with microdialysis probes...

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..of uncrosslinked and unaged GUR 1150HP ultra-high-molecular-weight polyethylene specimens, following different sterilization treatments (none, gamma-irradiation in air, gamma-irradiation in a nitrogen-rich atmosphere, ethylene oxide ..

..CLINICAL IMPLICATIONS: Unless low-speed handpieces are sterilized properly after each use, they pose a risk for crossinfection...

..can be considered efficient as long as they are sterilised in an autoclave (97%) and undergo periodic sterilization efficacy tests (76%)...

..shaver blades and 27 shaver blades that had been reprocessed with mechanical cleaning, functional testing, and sterilization with ethylene oxide. A spectrophotometer measured the amount of nucleic acid and protein...

..b>Sterilization levels meeting international requirements were attained in all cases with carriers inoculated with Geobacillus ..

..The reason it is so interesting to me is that the term 'back to basics' implies reverting to a simpler time in life - when by just sticking to the rules, life became easier. However, with decontamination this is not actually true...

Plasma-based sterilization is a promising alternative to the use of pure ethylene oxide (EO), for low-temperature clinical sterilization of medical instruments and devices...

..This article reports on experiences of applying these methods and suggests ways to handle difficult products...

..disposable devices were contaminated with bacteria-spiked human blood and underwent four different pre-sterilization protocols, including a chlorine-releasing agent, a polyphenolic emulsion, and an enzymatic detergent...

..This article discusses the major changes in the requirements, which will need to be addressed to demonstrate compliance with the revised standards...

..The design of the instrument holder may have been a factor in this result. More research is needed into the use of washer disinfectors in the cleaning of small dental instruments that have a complex surface structure...

..Sarah Tattersall reports on an initiative to encourage GP practices to comply with best practice in infection control by providing evidence on the advantages of purchasing single-use vaginal specula...

..Despite the re-use of disposable needles, medical injection practices are not likely to contribute significantly to HIV transmission in this region...

..After the sterilization step, infectious enterovirus was detectable in one (10%) of the samples, whereas two (20%) contained ..

..3) Promote safe health care practices equally for clients and staff. (4) Establish a zero-tolerance policy for iatrogenic HIV infections, with publicly reported monitoring and investigations...

..Even the use of retroflush cleaning was not totally effective. These findings suggest that in-hospital reprocessing of biopsy forceps with currently available equipment and cleaning methods is suboptimal...

..The suitability of these devices for cleaning and disinfection or sterilization was examined...

..The new methodology applied in the assessment of surface contamination is rapid and generally applicable and could be used more widely for routine monitoring of instrument cleanliness...

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..Health care workers should use the Bloodborne Pathogen Standard and Standard Precautions to determine the best method to reduce and/or eliminate bioburden...

..This article will review the mechanism of action of the air-driven atomizer and discuss the literature which demonstrates the associated a risk for patient cross-contamination...

..CONCLUSION: For small metal instruments, autoclaved packages in double-wrapped linen or double-wrapped plastic-paper combinations can be stored safely for at least 96 weeks...

..We showed that EC determination could be used for a rapid control of the effectiveness of a disinfection process performed with ethylene oxide...

..The combination of cleaning with citric acid followed by heat disinfection was the most effective in eliminating all biofilm components from the hydraulic circuit of the in vitro model...

..Reprocessing of the single-use devices tested did not result in endoscopic instruments that met acceptable standards for sterility at our institution...

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..It is hoped that this review and its recommendations will initiate needed discussion and resolution of the many issues identified...

..Bacteria's capability to acquire a resistant to disinfectants cause to search the new and more advance substances. Incorrect use of the antibacterial chemicals could accelerate this process...

..CONCLUSIONS: Endotracheal tubes can be reused sterilized safely. The physical integrity of ETT cuffs may be compromised by glutaraldehyde or ethylene oxide sterilization treatments.

..The use of E. coli as an indicator bacterium for the validation of Salmonella results should be considered...

..Ultrasonic baths are significantly more effective than hand cleaning for these items of equipment...

..The results indicate that autoclaving for 30 minutes or immersion in 10% formalin for seven days could be effectively used for disinfection/sterilisation of extracted human teeth...