maternal age

Summary

Summary: The age of the mother in PREGNANCY.

Top Publications

  1. ncbi Impact of advanced maternal age on pregnancy outcome
    Muhieddine A-F Seoud
    Department of Obstetrics and Gynecology, American University of Beirut Medical Center, Beirut, Lebanon
    Am J Perinatol 19:1-8. 2002
  2. ncbi Advanced maternal age. Part I: obstetric complications
    Ihab M Usta
    Department of Obstetrics and Gynecology, American University of Beirut Medical Center, Beirut, Lebanon
    Am J Perinatol 25:521-34. 2008
  3. ncbi Maternal age and fetal loss: population based register linkage study
    A M Nybo Andersen
    Department of Epidemiology Research, Danish Epidemiology Science Centre, Statens Serum Institut, DK 2300 Copenhagen S, Denmark
    BMJ 320:1708-12. 2000
  4. ncbi Maternal characteristics and lifestyle factors and the risk of delivering high birth weight infants
    Janne Ørskou
    Perinatal Epidemiological Research Unit, Department of Obstetrics and Gynaecology, Aarhus University Hospital, Aarhus, Denmark
    Obstet Gynecol 102:115-20. 2003
  5. ncbi Paternal age at birth and high-functioning autistic-spectrum disorder in offspring
    Kenji J Tsuchiya
    Osaka Hamamatsu Joint Research Center for Child Mental Development OHJRC CMD, Hamamatsu University School of Medicine, Hamamatsu 431 3192, Japan
    Br J Psychiatry 193:316-21. 2008
  6. ncbi Advanced maternal age and risk of antepartum and intrapartum stillbirth
    Hamisu M Salihu
    Department of Epidemiology and Biostatistics, University of South Florida, Tampa, Florida, USA
    J Obstet Gynaecol Res 34:843-50. 2008
  7. ncbi Consanguinity and advanced maternal age as risk factors for reproductive losses in Alexandria, Egypt
    M M Mokhtar
    Department of Huiman Genetics, Medical Research Institute, Alexandria University, Egypt
    Eur J Epidemiol 17:559-65. 2001
  8. ncbi Advancing paternal age and autism
    Abraham Reichenberg
    Department of Psychiatry and Seaver Center for Autism Research, Mount Sinai School of Medicine, One Gustave L Levy Place, New York, NY 10029, USA
    Arch Gen Psychiatry 63:1026-32. 2006
  9. ncbi Paternal age and intelligence: implications for age-related genomic changes in male germ cells
    Dolores Malaspina
    New York State Psychiatric Institute and Columbia University, New York, NY 10032, USA
    Psychiatr Genet 15:117-25. 2005
  10. ncbi Racial differences in gene-specific DNA methylation levels are present at birth
    Ronald M Adkins
    University of Tennessee Health Science Center, Memphis, TN 48103, USA
    Birth Defects Res A Clin Mol Teratol 91:728-36. 2011

Research Grants

  1. Meiotic Chromosome Segregation in C. elegans
    Anne Villeneuve; Fiscal Year: 2009
  2. Meiotic Chromosome Segregation in C. elegans
    Anne M Villeneuve; Fiscal Year: 2010
  3. MICRONUTRIENTS AND MOTHER TO CHILD TRANSMISSION OF HIV
    Richard Semba; Fiscal Year: 2001
  4. Clinical Measures to Lower Genital Tract Trauma at Birth
    Leah Albers; Fiscal Year: 2004
  5. Maternal Morbidity and Mortality in Multiple Pregnancy
    Barbara Luke; Fiscal Year: 2006
  6. Plurality and Contemporary Infant Mortality Risks
    Barbara Luke; Fiscal Year: 2006
  7. Spontaneous Arousals in "CHIME" Infants at Risk for SIDS
    ROBERT DARNALL; Fiscal Year: 2006
  8. Quasi-experimental studies of early risk factors for severe psychopathology
    Paul Lichtenstein; Fiscal Year: 2010
  9. THE BIODEMOGRAPHY OF HUMAN LONGEVITY--A TRAINING PROGRAM
    Leonid Gavrilov; Fiscal Year: 2005
  10. Advanced Reproductive Technology and Infant Health
    Marianne Bitler; Fiscal Year: 2005

Detail Information

Publications302 found, 100 shown here

  1. ncbi Impact of advanced maternal age on pregnancy outcome
    Muhieddine A-F Seoud
    Department of Obstetrics and Gynecology, American University of Beirut Medical Center, Beirut, Lebanon
    Am J Perinatol 19:1-8. 2002
    ..Parity was significantly higher in cases compared with controls (3.2 vs. 1.8). Advanced maternal age, compared with younger age, was associated with significantly higher rates of preterm delivery (16.0 vs. 8...
  2. ncbi Advanced maternal age. Part I: obstetric complications
    Ihab M Usta
    Department of Obstetrics and Gynecology, American University of Beirut Medical Center, Beirut, Lebanon
    Am J Perinatol 25:521-34. 2008
    More women are postponing pregnancy into the fourth and fifth decades of life for a variety of reasons. Advanced maternal age, traditionally defined as age more than 35 years, has been associated with increased obstetric morbidity and ..
  3. ncbi Maternal age and fetal loss: population based register linkage study
    A M Nybo Andersen
    Department of Epidemiology Research, Danish Epidemiology Science Centre, Statens Serum Institut, DK 2300 Copenhagen S, Denmark
    BMJ 320:1708-12. 2000
    To estimate the association between maternal age and fetal death (spontaneous abortion, ectopic pregnancy, stillbirth), taking into account a woman's reproductive history.
  4. ncbi Maternal characteristics and lifestyle factors and the risk of delivering high birth weight infants
    Janne Ørskou
    Perinatal Epidemiological Research Unit, Department of Obstetrics and Gynaecology, Aarhus University Hospital, Aarhus, Denmark
    Obstet Gynecol 102:115-20. 2003
    ....
  5. ncbi Paternal age at birth and high-functioning autistic-spectrum disorder in offspring
    Kenji J Tsuchiya
    Osaka Hamamatsu Joint Research Center for Child Mental Development OHJRC CMD, Hamamatsu University School of Medicine, Hamamatsu 431 3192, Japan
    Br J Psychiatry 193:316-21. 2008
    ..Previous studies have reported the association between advanced paternal age at birth and the risk of autistic-spectrum disorder in offspring, including offspring with intellectual disability...
  6. ncbi Advanced maternal age and risk of antepartum and intrapartum stillbirth
    Hamisu M Salihu
    Department of Epidemiology and Biostatistics, University of South Florida, Tampa, Florida, USA
    J Obstet Gynaecol Res 34:843-50. 2008
    ..We sought to assess the risk of antepartum and intrapartum stillbirth subtypes among women of advanced age...
  7. ncbi Consanguinity and advanced maternal age as risk factors for reproductive losses in Alexandria, Egypt
    M M Mokhtar
    Department of Huiman Genetics, Medical Research Institute, Alexandria University, Egypt
    Eur J Epidemiol 17:559-65. 2001
    ..This study aimed at delineating the role of consanguinity and advanced maternal age on reproductive losses in Alexandria, Egypt...
  8. ncbi Advancing paternal age and autism
    Abraham Reichenberg
    Department of Psychiatry and Seaver Center for Autism Research, Mount Sinai School of Medicine, One Gustave L Levy Place, New York, NY 10029, USA
    Arch Gen Psychiatry 63:1026-32. 2006
    ..Maternal and paternal ages are associated with neurodevelopmental disorders...
  9. ncbi Paternal age and intelligence: implications for age-related genomic changes in male germ cells
    Dolores Malaspina
    New York State Psychiatric Institute and Columbia University, New York, NY 10032, USA
    Psychiatr Genet 15:117-25. 2005
    ..There are also substantial genetic influences on intelligence, so de novo genetic events in male germ cells, which accompany advancing paternal age, may plausibly influence offspring intelligence...
  10. ncbi Racial differences in gene-specific DNA methylation levels are present at birth
    Ronald M Adkins
    University of Tennessee Health Science Center, Memphis, TN 48103, USA
    Birth Defects Res A Clin Mol Teratol 91:728-36. 2011
    ..The origin of these differences is inadequately understood, and this is a question of specific relevance to childhood and adult cancer...
  11. ncbi Validation of microarray comparative genomic hybridization for comprehensive chromosome analysis of embryos
    Cristina Gutiérrez-Mateo
    Reprogenetics, Livingston, New Jersey, USA
    Fertil Steril 95:953-8. 2011
    ..To validate and determine the best array-comparative genomic hybridization (aCGH; array-CGH) protocols for preimplantation genetic screening (PGS)...
  12. ncbi Monozygotic twinning associated with assisted reproductive technologies: a review
    K I Aston
    Andrology and IVF Laboratories, Department of Surgery, University of Utah School of Medicine, Salt Lake City, Utah 84108, USA
    Reproduction 136:377-86. 2008
    ..birth rates have increased markedly in developed countries since the 1970s for two primary reasons: increasing maternal age and the advent and increasing use of fertility treatments...
  13. ncbi The effect of delaying childbirth on primary cesarean section rates
    Gordon C S Smith
    Department of Obstetrics and Gynaecology, Cambridge University, The Rosie Hospital, Cambridge, United Kingdom
    PLoS Med 5:e144. 2008
    ..The aims of the present study were (1) to characterize the association between maternal age and the outcome of labor, (2) to determine the proportion of the increase in primary cesarean rates that could ..
  14. ncbi Is pregnancy over 45 with very high parity related with adverse maternal and fetal outcomes?
    A Kale
    Department of Obstetrics and Gynecology, Dicle University School of Medicine, Diyarbakir, Turkey
    Clin Exp Obstet Gynecol 36:120-2. 2009
    ..To examine whether very high parity and age over 45 years are related with adverse maternal and fetal outcomes...
  15. ncbi Chromosome mosaicism in cleavage-stage human embryos: evidence of a maternal age effect
    Santiago Munne
    Institute for Reproductive Medicine and Science, Saint Barnabas Medical Centre, Livingston, NJ 07052, USA
    Reprod Biomed Online 4:223-32. 2002
    ..While overall mosaicism did not increase with maternal age, the average maternal age of the embryos that had mosaics caused by mitotic non-disjunction was significantly ..
  16. ncbi Evidence that a defective spindle assembly checkpoint is not the primary cause of maternal age-associated aneuploidy in mouse eggs
    Francesca E Duncan
    Department of Biology, University of Pennsylvania, Philadelphia, Pennsylvania, USA
    Biol Reprod 81:768-76. 2009
    Advanced maternal age is unequivocally associated with increased aneuploidy in human eggs and infertility, but the molecular basis for this phenomenon is unknown...
  17. ncbi Estimated autism risk and older reproductive age
    Marissa D King
    Institute for Social and Economic Research and Policy, Columbia University, New York, NY 10027, USA
    Am J Public Health 99:1673-9. 2009
    ..We sought to estimate the risk for autism associated with maternal and paternal age across successive birth cohorts...
  18. ncbi Young maternal age and risk of intrapartum stillbirth
    Ronee E Wilson
    Department of Epidemiology and Biostatistics, University of South Florida, Tampa, FL, USA
    Arch Gynecol Obstet 278:231-6. 2008
    ..To determine the risk of intrapartum stillbirth among teen mothers...
  19. ncbi Influence of thyroid autoimmunity and maternal age on the risk of miscarriage
    Lino Sieiro Netto
    Faculdade de Medicina Serviços de Endocrinologia, HUCFF, UFRJ, Rio de Janeiro, Brazil
    Am J Reprod Immunol 52:312-6. 2004
    ..Another point to be considered is the association of high risk of abortion and maternal age. The aim of the present study was to evaluate if the association between TAI and miscarriage could also be ..
  20. ncbi Risk of autism and increasing maternal and paternal age in a large north American population
    Judith K Grether
    Environmental Health Investigations Branch, California Department of Public Health, Richmond, California 94804, USA
    Am J Epidemiol 170:1118-26. 2009
    ..In adjusted models that included age of the other parent and demographic covariates, a 10-year increase in maternal age was associated with a 38% increase in the odds ratio for autism (odds ratio = 1.38, 95% confidence interval: 1...
  21. ncbi Maternal age and paternal age are associated with distinct childhood behavioural outcomes in a general population birth cohort
    Sukanta Saha
    Queensland Centre for Mental Health Research, The Park Centre for Mental Health, Locked Bag 500, Richlands Q4077, Australia
    Schizophr Res 115:130-5. 2009
    ..The aim of the study was to examine the relationship between paternal and maternal ages and selected behavioural measures in children using a large birth cohort...
  22. ncbi Trends in the occurrence, determinants, and consequences of multiple births
    Beatrice Blondel
    Epidemiological Research Unit on Perinatal and Women s Health, Institut National de la Sante et de la Recherche Medicale INSERM, Villejuif, France
    Semin Perinatol 26:239-49. 2002
    ..to one third of the increase in twin or triplet pregnancies are attributable to a contemporaneous increase in maternal age. Furthermore, in countries with high occurrence of multiple births, 30% to 50% of twin pregnancies and at least ..
  23. ncbi Effect of Body Mass Index on pregnancy outcomes in nulliparous women delivering singleton babies
    Sohinee Bhattacharya
    Dugald Baird Centre for Research on Women s Health, Aberdeen Maternity Hospital, Aberdeen, UK
    BMC Public Health 7:168. 2007
    ..In a population based cohort study, using routinely collected data, this paper examines the effect of increasing Body Mass Index (BMI) on pregnancy outcomes in nulliparous women delivering singleton babies...
  24. ncbi Dystocia increases with advancing maternal age
    Ann Treacy
    National Maternity Hospital, Dublin, Ireland
    Am J Obstet Gynecol 195:760-3. 2006
    OBJECTIVE: The purpose of this study was to assess the influence of maternal age on obstetric indices of uterine efficiency in spontaneous nulliparous labor managed according to a standardized protocol in order to determine whether ..
  25. ncbi Recombination rate and reproductive success in humans
    Augustine Kong
    deCODE Genetics, Sturlugata 8, IS 101 Reykjavik, Iceland
    Nat Genet 36:1203-6. 2004
    ..meioses each, and found a positive correlation between maternal recombination counts of an offspring and maternal age. We postulated that the recombination rate of eggs does not increase with maternal age, but that the apparent ..
  26. ncbi Maternal and birth characteristics in relation to childhood leukaemia
    Danise Podvin
    Department of Epidemiology, School of Public Health and Community Medicine, University of Washington, Seattle, 98195, USA
    Paediatr Perinat Epidemiol 20:312-22. 2006
    ..b>Maternal age 35+ years (odds ratio [OR] 1.5; 95% confidence interval [CI] 1.1, 2.0), infant birthweight 4,000+ g (OR 1...
  27. ncbi Cesarean birth in the United States: epidemiology, trends, and outcomes
    Marian F MacDorman
    Reproductive Statistics Branch, Division of Vital Statistics, National Center for Health Statistics, Centers for Disease Control and Prevention, 3311 Toledo Road, Room 7318, Hyattsville, MD 20782, USA
    Clin Perinatol 35:293-307, v. 2008
    ..quot; Several studies note an increased risk for neonatal and maternal mortality for medically elective cesareans compared with vaginal births...
  28. ncbi Longitudinal reference ranges for estimated fetal weight
    Synnøve Lian Johnsen
    Department of Obstetrics and Gynecology, Haukeland University Hospital, Bergen, Norway
    Acta Obstet Gynecol Scand 85:286-97. 2006
    ..The aims of the present study were to establish reference ranges for the growth of estimated fetal weight (EFW) between gestational weeks 20 and 42 and to determine the effect of fetal and maternal factors...
  29. ncbi Maternal age and the risk of stillbirth throughout pregnancy in the United States
    Uma M Reddy
    Pregnancy and Perinatology Branch, National Institute of Child Health and Human Development, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, USA
    Am J Obstet Gynecol 195:764-70. 2006
    OBJECTIVE: The objective of the study was to examine the relationship of maternal age with stillbirth risk throughout gestation...
  30. ncbi Paternal age and maternal age are risk factors for miscarriage; results of a multicentre European study
    Elise de La Rochebrochard
    INED (National Demographic Studies Institute, 75020 Paris, France
    Hum Reprod 17:1649-56. 2002
    BACKGROUND: It is well known that miscarriage risk increases with age. However, studies usually investigate only maternal age effects...
  31. ncbi Early infant feeding and risk of type 1 diabetes mellitus-a nationwide population-based case-control study in pre-school children
    J Rosenbauer
    Institute of Biometrics and Epidemiology, German Diabetes Centre, Leibniz Institute at Heinrich Heine University Düsseldorf, Germany uni duesseldorf de
    Diabetes Metab Res Rev 24:211-22. 2008
    ..Reducing potential bias and the variety of exposures, we investigated the association between type 1 diabetes risk and nutritional and environmental exposures in pre-school children...
  32. ncbi Indications for cesarean deliveries in Norway
    Toril Kolås
    Department of Obstetrics and Gynecology, Lillehammer County Hospital, Norway
    Am J Obstet Gynecol 188:864-70. 2003
    ..The purpose of this study was to investigate the indications for cesarean deliveries in Norway, related to type of operation, parity, and gestational age...
  33. ncbi Trends in maternal obesity and associated risks of adverse pregnancy outcomes in a population of Chinese women
    T Y Leung
    Department of Obstetrics and Gynaecology, The Chinese University of Hong Kong, Hong Kong, China
    BJOG 115:1529-37. 2008
    ..To assess the effect of increasing body mass index (BMI) on pregnancy outcome in a population of Chinese women...
  34. ncbi Surveillance of cesarean section deliveries, New Jersey, 1999-2004
    Charles E Denk
    Maternal and Child Health Epidemiology Program, New Jersey Department of Health and Senior Services, Trenton, New Jersey08625-0364, USA
    Birth 33:203-9. 2006
    ..A sustained autonomous shift in practice patterns, patient preferences, or both seems the most likely driver of the overall trend...
  35. ncbi Maternal age and risk of stillbirth: a systematic review
    Ling Huang
    Health Surveillance and Epidemiology Division, Centre for Health Promotion, Public Health Agency of Canada, Ottawa, Ont
    CMAJ 178:165-72. 2008
    ..Studies regarding the relation between older maternal age and the risk of stillbirth have yielded inconsistent conclusions...
  36. ncbi Maternal age and chromosomally abnormal pregnancies: what we know and what we wish we knew
    Terry Hassold
    School of Molecular Biosciences and Center for Reproductive Biology, Washington State University, Pullman, Washington 99164, USA
    Curr Opin Pediatr 21:703-8. 2009
    The relationship between increasing maternal age and trisomy has been recognized for over 50 years and is one of the most important etiological factors associated with any human genetic disorder...
  37. ncbi Does young maternal age increase the risk of adverse obstetric, fetal and neonatal outcomes: a cohort study
    Claire M de Vienne
    Department of Obstetrics and Gynecology, University Hospital of Caen, France
    Eur J Obstet Gynecol Reprod Biol 147:151-6. 2009
    To determine whether young maternal age is associated with increased risks of adverse obstetric, fetal and perinatal outcomes.
  38. ncbi Registration of Down syndrome in the Medical Birth Registry of Norway: validity and time trends
    Kari Klungsøyr Melve
    Department of Public Health and Primary Health Care, University of Bergen, Bergen, Norway
    Acta Obstet Gynecol Scand 87:824-30. 2008
    ..To validate Down syndrome registration in the Medical Birth Registry of Norway (MBRN), 2001-2005, and study time trends and geographical differences in Down syndrome prevalence,1967-2005...
  39. ncbi Restricted fetal growth in sudden intrauterine unexplained death
    J Frederik Frøen
    Department of Obstetrics and Gynecology, Rikshospitalet University Clinic, University of Oslo, Oslo, Norway
    Acta Obstet Gynecol Scand 83:801-7. 2004
    ....
  40. ncbi Association between maternal age and the likelihood of a cesarean section: a population-based multivariate logistic regression analysis
    Herng Ching Lin
    School of Health Care Administration, Taipei Medical University, Taipei, Taiwan
    Acta Obstet Gynecol Scand 83:1178-83. 2004
    A majority of studies examining the relationship between advancing maternal age and the likelihood of cesarean section (CS) use data from regional samples or from a limited number of medical institutions...
  41. ncbi Pregnancy increases BMI in adolescents of a population-based birth cohort
    Denise P Gigante
    Post Graduate Program in Epidemiology, Universidade Federal de Pelotas, CP 464, 96001 970, Pelotas, RS, Brazil
    J Nutr 135:74-80. 2005
    ..Given the growing epidemic of obesity in low- and middle-income countries, particularly among women, efforts to reduce teenage pregnancy may also contribute to preventing overweight...
  42. ncbi Increased risks of neonatal and postneonatal mortality associated with teenage pregnancy had different explanations
    Xi Kuan Chen
    OMNI Research Group, Department of Obstetrics and Gynecology, University of Ottawa, Ottawa, Ontario, Canada K1H 8L6
    J Clin Epidemiol 61:688-94. 2008
    ..To determine the potential pathway of the association between teenage pregnancy and neonatal and postneonatal mortality...
  43. ncbi Socioeconomic factors and adolescent pregnancy outcomes: distinctions between neonatal and post-neonatal deaths?
    Barry P Markovitz
    Saint Louis University School of Public Health, St, Louis, Missouri, USA
    BMC Public Health 5:79. 2005
    Young maternal age has long been associated with higher infant mortality rates, but the role of socioeconomic factors in this association has been controversial...
  44. ncbi Trends in birth size and macrosomia in Queensland, Australia, from 1988 to 2005
    Petra H Lahmann
    The University of Queensland, School of Population Health, Herston Qld, Australia
    Paediatr Perinat Epidemiol 23:533-41. 2009
    ..Recorded birthweight (BW, g), birth length (BL, cm), gestational age (weeks), maternal age, ethnic origin and calculated ponderal index (PI, kg/m(3)) were used...
  45. ncbi Obstetric outcomes in nulliparous women aged 35 and over with singleton pregnancies conceived by in vitro fertilization
    Shunji Suzuki
    Department of Obstetrics and Gynecology, Japanese Red Cross Katsushika Maternity Hospital, 5 11 12 Tateishi, Katsushika ku, Tokyo, Japan
    Arch Gynecol Obstet 277:225-7. 2008
    ..To investigate obstetric outcomes in singleton pregnancies conceived by in vitro fertilization (IVF) to nulliparous women older than 35 compared to those of their younger counterparts...
  46. ncbi Plasmodium falciparum exposure in utero, maternal age and parity influence the innate activation of foetal antigen presenting cells
    Nadine Fievet
    UR010, Mother and Child Health in the Tropics, Institut de recherche pour le developpement IRD, Cotonou, Benin
    Malar J 8:251. 2009
    ....
  47. ncbi Maternal age-specific rates of fetal chromosomal abnormalities at 16-20 weeks' gestation in Korean pregnant women >or=35 years of age
    In Yang Park
    Departments of Obstetrics and Gynecology, College of Medicine, The Catholic University of Korea, Seoul, Korea
    Fetal Diagn Ther 27:214-21. 2010
    To provide estimates of maternal age-specific rates of fetal chromosomal abnormalities at 16-20 weeks' gestation for Korean women >or=35 years of age.
  48. ncbi Explaining differences in birth outcomes in relation to maternal age: the Generation R Study
    R Bakker
    The Generation R Study Group, Erasmus Medical Centre, Rotterdam, The Netherlands
    BJOG 118:500-9. 2011
    To examine the association between maternal age and birth outcomes, and to investigate the role of sociodemographic and lifestyle-related determinants.
  49. ncbi [Is fertility of the population changed?]
    Tom Tanbo
    Nasjonalt kompetansesenter for kvinnehelse Kvinneklinikken, Rikshospitalet, 0027 Oslo
    Tidsskr Nor Laegeforen 128:330-3. 2008
  50. ncbi Obstetrical risks in the older primigravida
    Mehreen Mehdi Naqvi
    Department of Obstetrics and Gynaecology, POF Hospital, Wah Cantt
    J Coll Physicians Surg Pak 14:278-81. 2004
    ..CONCLUSION: Advanced maternal age has been associated with an increased risk of various complications like hypertension, diabetes, and ..
  51. ncbi Advanced maternal age. Part II: long-term consequences
    Anwar H Nassar
    Department of Obstetrics and Gynecology, American University of Beirut Medical Center, Beirut, Lebanon
    Am J Perinatol 26:107-12. 2009
    In addition to the possible association between pregnancy in women with advanced maternal age and increased rates of obstetric and perinatal complications, those women and their children might suffer from long-term sequelae...
  52. ncbi Infertility, infertility treatment and psychomotor development: the Danish National Birth Cohort
    Jin Liang Zhu
    The Danish Epidemiology Science Centre, University of Aarhus, Aarhus, Denmark
    Paediatr Perinat Epidemiol 23:98-106. 2009
    ..These results suggest that a long TTP may be associated with a modest developmental delay. Infertility treatment, especially ICSI, may be associated with a slight delay for some of these early milestones...
  53. ncbi Maternal occupation and risk for low birth weight delivery: assessment using state birth registry data
    John D Meyer
    Section of Occupational and Environmental Health, Center for Interdisciplinary Research in Women s Health, Division of Public Health and Population Sciences, University of Connecticut Health Center, Farmington, Connecticut 06030 6210, USA
    J Occup Environ Med 50:306-15. 2008
    ..To determine the effects of employment on low birth weight (LBW) in a service-based economy, we evaluated the association of LBW delivery with occupational data collected in a state birth registry...
  54. ncbi Maternal age, paternal age and new-onset hypertension in late pregnancy
    Xi-Kuan Chen
    OMNI Research Group, Department of Obstetrics and Gynecology, University of Ottawa, Ottawa, Ontario, Canada
    Hypertens Pregnancy 25:217-27. 2006
    OBJECTIVE: To examine the association between maternal age, paternal age, and new-onset hypertension in late pregnancy...
  55. ncbi Maternal age and risk of fetal death in singleton gestations: USA, 1995-2000
    J C Canterino
    Department of Obstetrics, Gynecology and Reproductive Sciences, University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School/Robert Wood Johnson University Hospital, New Brunswick, USA
    J Matern Fetal Neonatal Med 15:193-7. 2004
    OBJECTIVE: To determine the magnitude of risk for fetal death among singleton pregnancies in relation to maternal age, and to compare the risks with other common indications for fetal testing...
  56. ncbi Pregnancy outcomes in women of very advanced maternal age
    Leonie K Callaway
    Mater Misericordiae Hospitals, Queensland, Australia
    Aust N Z J Obstet Gynaecol 45:12-6. 2005
    To assess outcomes for pregnancies progressing beyond 20 weeks' gestation in women of very advanced maternal age.
  57. ncbi Advanced maternal age and adverse perinatal outcome
    Bo Jacobsson
    Perinatal Centre, Department of Obstetrics and Gynecology, Sahlgrenska University Hospital Ostra, S 416 85 Goteborg, Sweden
    Obstet Gynecol 104:727-33. 2004
    The aim of this study was to investigate the influence of maternal age on perinatal and obstetric outcome in women aged 40-44 years and those 45 years or older and to estimate whether adverse outcome was related to intercurrent illness ..
  58. ncbi Pregnancy at 40 and over: a case-control study in a developing country
    D S Weerasekera
    Department of Obstetrics and Gynaecology, Faculty of Medical Sciences, University of Sri Jayewardenepura, Nugegoda, Sri Lanka
    J Obstet Gynaecol 23:625-7. 2003
    ..14.7%, respectively). When corrected for repeat sections and sections conducted specifically for advanced maternal age, the difference was less but still significant (42.7% vs. 32.7%)...
  59. ncbi Maternal age-related differential global expression profiles observed in human oocytes
    Nury M Steuerwald
    ART Institute of New York and New Jersey, Livingston, New Jersey 07039, USA
    Reprod Biomed Online 14:700-8. 2007
    ..including cell cycle regulation, cytoskeletal structure, energy pathways, transcription control, and stress responses, are influenced by maternal age. These results are corroborated by a complementary extensive study using mouse oocytes.
  60. ncbi [Impact of advanced maternal age on fecundity and women's and children's health]
    B Khoshnood
    INSERM, UMR S149, IFR69, recherches épidémiologiques sur la santé périnatale et la santé des femmes, 16, avenue Paul Vaillant Couturier, 94807 Villejuif Cedex, France
    J Gynecol Obstet Biol Reprod (Paris) 37:733-47. 2008
    There has been a consistent trend towards delayed childbearing in most Western countries. We present a review of the current epidemiological understanding of the effects of advanced maternal age on fecundity, maternal and child health.
  61. ncbi Maternal age-related rates of gestational trophoblastic disease
    Alon D Altman
    Izaak Walton Killam Health Centre, Queen Elizabeth II Health Science Centre, Dalhousie University, Halifax, Nova Scotia, Canada
    Obstet Gynecol 112:244-50. 2008
    To estimate the incidence of gestational trophoblastic disease in Nova Scotia and to evaluate the effect of time and maternal age on these rates.
  62. ncbi Fetal nasal bone in screening for trisomies 21, 18 and 13 and Turner syndrome at 11-13 weeks of gestation
    K O Kagan
    Harris Birthright Research Centre for Fetal Medicine, King s College Hospital, London, UK
    Ultrasound Obstet Gynecol 33:259-64. 2009
    ..screening for aneuploidies by including assessment of the fetal nasal bone in the combined test of maternal age, fetal nuchal translucency (NT) thickness, fetal heart rate (FHR) and serum free beta-human chorionic ..
  63. ncbi Maternal age and malformations in singleton births
    L M Hollier
    Department of Obstetrics and Gynecology, University of Texas Southwestern Medical Center, Dallas, Texas, USA
    Obstet Gynecol 96:701-6. 2000
    To examine the effect of maternal age on incidence of nonchromosomal fetal malformations.
  64. ncbi Maternal age and trisomy--a unifying mechanism of formation
    J Wolstenholme
    Cytogenetics Laboratory, Northern Genetics Service, University of Newcastle upon Tyne, 20 Claremont Place, Newcastle upon Tyne NE2 4AA, UK
    Chromosoma 109:435-8. 2000
    The mechanism of trisomy formation and its relationship to increased maternal age is not understood...
  65. ncbi Stillbirth at term in women of advanced maternal age in the United States: when could the antenatal testing be initiated?
    Mert Ozan Bahtiyar
    Yale University School of Medicine, Section of Maternal Fetal Medicine, New Haven, Connecticut, USA
    Am J Perinatol 25:301-4. 2008
    We sought to determine if advanced maternal age (AMA) is a risk factor for intrauterine fetal demise (IUFD). We used a U.S...
  66. ncbi Maternal age effects on longevity in Drosophila melanogaster populations of different origin
    M Yilmaz
    Department of Biology, Hacettepe University, 06800 Beytepe, Ankara, Turkey
    Biogerontology 9:163-8. 2008
    Offspring from Drosophila melanogaster populations of different maternal age were derived and aged. Our results showed that offspring longevities do not follow inversely the mother's ages i.e...
  67. ncbi Brief report: parental age and the sex ratio in autism
    Alene Anello
    Harvard University, Cambridge, MA, USA
    J Autism Dev Disord 39:1487-92. 2009
    ..ratio was significantly decreased with increasing paternal age groups and remained so after also adjusting for maternal age. No significant relationship between maternal age group and the M:F ratio was observed...
  68. ncbi Comparison of models of maternal age-specific risk for Down syndrome live births
    J K Morris
    Department of Environmental and Preventive Medicine, Wolfson Institute of Preventive Medicine, St Bartholomew s and the Royal London School of Medicine and Dentistry, Charterhouse Square, London EC1M 6BQ, UK
    Prenat Diagn 23:252-8. 2003
    To display and compare the different published formulae that specify the association between maternal age and the risk of a Down syndrome live birth.
  69. ncbi Obstetric outcomes in donor oocyte pregnancies compared with advanced maternal age in in vitro fertilization pregnancies
    Sacha A Krieg
    Department of Obstetrics and Gynecology, Stanford University School of Medicine, Stanford, California, USA
    Fertil Steril 90:65-70. 2008
    ..To evaluate obstetric complications in women who conceived through donated oocytes compared with women who conceived through assisted reproduction using autologous oocytes...
  70. ncbi Paternal and maternal ages at conception and risk of bipolar affective disorder in their offspring
    P R Menezes
    Department of Preventive Medicine, University of Sao Paulo, Brazil
    Psychol Med 40:477-85. 2010
    ..age and their offspring's risk of schizophrenia has been observed, with no independent association with maternal age. The relationship of paternal and maternal ages with risk of bipolar affective disorders (BPAD) in the ..
  71. ncbi Effect of maternal age and fertility treatment on the increase in multiple births in Japan: vital statistics, 1974-2009
    Syuichi Ooki
    Department of Health Science, Ishikawa Prefectural Nursing University, Ishikawa, Japan
    J Epidemiol 21:507-11. 2011
    The present study used vital-statistics data to estimate the effect of maternal age and fertility treatment on the number and rate of multiple live births in Japan from 1974 through 2009.
  72. ncbi Advanced maternal age and adverse perinatal outcomes in an Asian population
    T sang T ang Hsieh
    Department of Obstetrics and Gynecology, Chang Gung Memorial Hospital, Taipei 105, Taiwan
    Eur J Obstet Gynecol Reprod Biol 148:21-6. 2010
    To investigate (1) whether there is an increasing trend in the mean maternal age at the birth of the first child and in the group of women giving birth at age 35 or older, and (2) the association between advanced maternal age and adverse ..
  73. ncbi Gestational diabetes in Iran: incidence, risk factors and pregnancy outcomes
    Maryam Keshavarz
    Department of Ob and Gyn, Shahrood Faculty of Medical Sciences and Health Services, Shohada Street, Shahrood, Semnan, P O Box 36184, Iran
    Diabetes Res Clin Pract 69:279-86. 2005
    ..We recommend screening for GDM in Iran, but further evaluation of selective screening and cost effectiveness will need to be performed. Measures to improve the outcome of GDM pregnancy will also need to be addressed in the future...
  74. ncbi Pregnancy late in life: a hospital-based study of birth outcomes
    Ali Delpisheh
    Child and Reproductive Health Group, Liverpool School of Tropical Medicine, Liverpool, UK
    J Womens Health (Larchmt) 17:965-70. 2008
    ..Pregnancy in older women is of great relevance, particularly in developed countries where many women experience pregnancy late in the childbearing age...
  75. ncbi Pregnancy outcome in patients with primary Sjögren's syndrome. a case-control study
    Hans Jacob Haga
    Department of Rheumatology, Esbjerg Central Hospital, 6700 Esbjerg, Denmark
    J Rheumatol 32:1734-6. 2005
    ..To study the outcome of pregnancy in patients with primary Sjögren's syndrome (pSS)...
  76. ncbi Outcome of second delivery after prior macrosomic infant in women with normal glucose tolerance
    Rhona Mahony
    Departments of Obstetrics and Gynecology, National Maternity Hospital and University College Dublin, Ireland
    Obstet Gynecol 107:857-62. 2006
    ..Conversely, primiparous macrosomic cesarean delivery conveyed a high risk (56%) for repeat intrapartum cesarean whether macrosomia recurred or not. LEVEL OF EVIDENCE: II-2...
  77. ncbi [The analysis of twin pregnancy and labour in the Department of Obstetrics, Medical Academy, Gdańsk]
    Krzysztof Preis
    ,
    Ginekol Pol 76:214-8. 2005
    ..CONCLUSIONS: At the transverse presentation of the second twin elective cesarean section seems better for the second twin...
  78. ncbi Impact of maternal age on obstetric outcome
    Jane Cleary-Goldman
    Columbia University Medical Center, New York, New York, USA
    Obstet Gynecol 105:983-90. 2005
    To estimate the effect of maternal age on obstetric outcomes.
  79. ncbi Outcome of induced labour in pregnancies at 41 weeks gestation and over in Saudi Arabia
    A A Sobande
    College of Medicine and Medical Sciences, King Khalid University, Abha, Saudi Arabia
    East Mediterr Health J 9:316-23. 2003
    ..Although more perinatal complications occurred when induction was carried out at 42 weeks, the results were not statistically significant. A large prospective clinical trial is indicated...
  80. ncbi High parity and fetal morbidity outcomes
    Muktar H Aliyu
    Department of Epidemiology and Department of Maternal and Child Health, University of Alabama at Birmingham, Birmingham, Alabama, USA
    Obstet Gynecol 105:1045-51. 2005
    ..However, the impact of heightened parity is more manifest as shortened gestation rather than physical size restriction. These findings could prove beneficial for counseling women of high parity...
  81. ncbi [Pregnancy beyond age 40 in 382 women: a retrospective study in Reunion Island]
    H Roman
    Service de Gynecologie et Obstetrique, Groupe Hospitalier Sud Reunion, 97448 Saint Pierre, Ile de La Réunion, France
    J Gynecol Obstet Biol Reprod (Paris) 33:615-22. 2004
    ..To examine obstetrical and neonatal outcomes among women age 40 years and older...
  82. ncbi Comparison of the criteria forgestational diabetes mellitus by NDDG and Carpenter and Coustan, and the outcomes of pregnancy
    A Gokcel
    Endocrinology and Metabolism Division, Baskent University, Adana, Turkey
    J Endocrinol Invest 25:357-61. 2002
    ..Tight glycemic control might decrease the prevalence of caesarian delivery, pre-eclampsia, pre-term delivery and hypoglycemia of the infant...
  83. ncbi Use of uterine Doppler in an Australian level II maternity hospital
    Mariette J C Nagtegaal
    Women s and Children Division Lyell McEwin Hospital, University of Adelaide, Elizabeth Vale, South Australia, Australia
    Aust N Z J Obstet Gynaecol 45:424-9. 2005
    ..To evaluate the clinical usefulness of uterine Doppler...
  84. ncbi Racial comparisons of thyroid function and autoimmunity during pregnancy and the postpartum period
    Jason A Walker
    Catawba Women s Center, Hickory, North Carolina, USA
    Obstet Gynecol 106:1365-71. 2005
    ..To evaluate thyroid function and the prevalence of thyroid peroxidase (TPO) antibody and autoimmunity in African-American and white women during pregnancy and the postpartum period...
  85. ncbi Monochorionic monoamniotic twins: neonatal outcome
    L Cordero
    Department of Pediatrics and Obstetrics, Division of Neonatal Perinatal Medicine, College of Medicine and Public Health, The Ohio State University Medical Center, Columbus, OH 43210 1228, USA
    J Perinatol 26:170-5. 2006
    ..Monochorionic monoamniotic twins (MoMo) occur in one of 10,000 pregnancies. Cord entanglement, malformations, twin-to-twin transfusion syndrome (TTS) and prematurity are responsible for their high perinatal morbidity and mortality...
  86. ncbi Preterm delivery but not intrauterine growth retardation is associated with young maternal age among primiparae in rural Nepal
    Christine P Stewart
    Department of International Health, Center for Human Nutrition, Johns Hopkins Bloomberg School of Public Health, 615 N Wolfe Street, Room W2505, Baltimore, MD 21205 2103, USA
    Matern Child Nutr 3:174-85. 2007
    ..96; 95% CI = 0.90-1.02) or small for gestational age (OR = 1.01; 95% CI = 0.94-1.08) per year of increasing maternal age among primiparae...
  87. ncbi [Twin pregnancies in southern Reunion Island: a three-year cross-sectional study of risk factors and complications]
    P Gerardin
    Service de Neonatologie, Réanimation néonatale et pédiatrique, Groupe Hospitalier Sud Reunion, BP 350, 97448 Saint Pierre cedex, Ile de La Réunion
    J Gynecol Obstet Biol Reprod (Paris) 35:804-12. 2006
    ..To describe characteristics of multiples pregnancies in southern Reunion Island...
  88. ncbi Analysis of birth weight in Metu Karl hospital: South West Ethiopia
    Gezahegn Nekatibeb
    Public Health Faculty, Jimma University, PO Box 480, Jimma, Ethiopia
    Ethiop Med J 45:195-202. 2007
    ..The objective of this study was to determine birth weight distribution and its association with some risk factors among newborns delivered in Metu Karl hospital Metu town (South-West Ethiopia) from February 2003 - February 2005...
  89. ncbi [A descriptive study of psychiatric population at Instituto Nacional de Perinatología]
    José Gabriel Espindola Hernández
    Departamento de Psicologia, UNAM
    Ginecol Obstet Mex 74:476-82. 2006
    ..To establish a description of the psychiatric population of the Instituto Nacional de Perinatología (INPer), as well as of the exposed newborns to psychopharmacological treatment during the gestation...
  90. ncbi Does the number of previous caesarean deliveries affect maternal outcome and complication rates?
    H A Alchalabi
    Department of Obstetrics and Gynaecology, Jordan University of Science and Technology, Irbid, Jordan
    East Mediterr Health J 13:544-50. 2007
    ..Post-operative pyrexia was commoner in women with 3 or more previous caesarean sections compared to those undergoing their first one...
  91. ncbi Ultrasonographic measurement of cervical length in predicting mode of delivery after oxytocin induction
    Ali Yanik
    Department of Obstetrics and Gynecologym, Cumhuriyet University Faculty of Medicine, Sivas, Turkey
    Adv Ther 24:748-56. 2007
    ..explore the value of transvaginal ultrasonographic cervical length measurement, in addition to gestational age, maternal age, parity, Bishop score, and weight of the newborn, in predicting the mode of delivery in pregnancies in which ..
  92. ncbi Clinical significance of uterine scar dehiscence in women with previous cesarean delivery: prevalence and independent risk factors
    Asher Bashiri
    Department of Obstetrics and Gynecology, Faculty of Health Sciences, Soroka University Medical Center, Ben Gurion University of the Negev, Beer Sheva, Israel
    J Reprod Med 53:8-14. 2008
    ..To determine the prevalence and risk factors for uterine scar dehiscence in women following cesarean delivery (CD)...
  93. ncbi Outcome and growth of infants fetally exposed to heart block-associated maternal anti-Ro52/SSA autoantibodies
    Amanda Skog
    Rheumatology Unit, Department of Medicine, Karolinska Institutet, Stockholm, Sweden
    Pediatrics 121:e803-9. 2008
    ....
  94. ncbi The Asian birth outcome gap
    Cheng Qin
    School of Public Health, University of California, Berkeley, USA
    Paediatr Perinat Epidemiol 20:279-89. 2006
    ..Significant differences in perinatal health across Asian subgroups deserve ethnicity-specific interventions addressing PTD, teen pregnancy, maternal education, parity and access to prenatal care...
  95. ncbi Sonographic prediction of significant intertwin birth weight discordance
    Yao-Lung Chang
    Department of Obstetrics and Gynecology, Chang Gung Memorial Hospital Linkou Medical Center, 5 Fu-Shin Road, Kwei-Shan, Tao-Yuan, Taiwan
    Eur J Obstet Gynecol Reprod Biol 127:35-40. 2006
    ..In order to obtain a higher sensitivity, the cut-off value of estimated birth weight discordance needs to be decreased by 5%...
  96. ncbi Is fetal gender associated with emergency department visits for asthma during pregnancy?
    Akerke Baibergenova
    Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada
    J Asthma 43:293-9. 2006
    ..To investigate if fetal gender (1) affects the risk of having an emergency department (ED) visit for asthma; and (2) is associated with adverse pregnancy outcomes among women who had at least one visit to the ED for asthma during pregnancy...
  97. ncbi The National Congenital Anomalies Register in the United Arab Emirates
    H Al Hosani
    Central Department of Maternal and Child Health, Ministry of Health, Abu Dhabi, United Arab Emirates
    East Mediterr Health J 11:690-9. 2005
    ..Birth defects were more common with older maternal age, grand multiparity, male babies, low-birth-weight babies and premature babies.
  98. ncbi Prediction of maternal complications and adverse infant outcome at admission for temporizing management of early-onset severe hypertensive disorders of pregnancy
    Wessel Ganzevoort
    Department of Obstetrics and Gynecology, Academic Medical Centre, Amsterdam, The Netherlands
    Am J Obstet Gynecol 195:495-503. 2006
    ..We explored the association between clinical parameters at admission and the subsequent development of major maternal complications or adverse infant outcome in women with hypertensive complications of pregnancy remote from term...
  99. ncbi Effects of gestational weight gain and body mass index on obstetric outcome in Sweden
    M Cedergren
    Division of Obstetrics and Gynecology, Department of Molecular and Clinical Medicine, Faculty of Health Sciences, Linkoping University, Linkoping, Sweden
    Int J Gynaecol Obstet 93:269-74. 2006
    ..The objective of this study was to estimate the effects of low and high gestational weight gain, in different maternal Body Mass Index (BMI) classes, on obstetric and neonatal outcomes...
  100. ncbi Pregnancy outcome after cervical cone excision: a case-control study
    Katrine Donvold Sjøborg
    Department of Obstetrics and Gynecology, Oestfold Hospital Trust, Fredrikstad, Norway
    Acta Obstet Gynecol Scand 86:423-8. 2007
    ..Outcome measures were perinatal mortality, length of gestation, birth weight and preterm premature rupture of membranes (pPROM)...
  101. ncbi Placental weight and its ratio to birth weight in normal pregnancy at Songkhlanagarind Hospital
    Manop Janthanaphan
    Department of Obstetrics and Gynecology, Faculty of Medicine, Prince of Songkla University, Songkhla, Thailand
    J Med Assoc Thai 89:130-7. 2006
    ..The placental weight to birth weight ratio decreased slightly with advancing gestational age. Abnormal placental weight and its ratio were significantly associated with some adverse pregnancy outcomes...

Research Grants72

  1. Meiotic Chromosome Segregation in C. elegans
    Anne Villeneuve; Fiscal Year: 2009
    ..of the plan are highly relevant to understanding how features of chromosome organization contribute to assembly and function of the female meiotic spindle, a process that becomes increasingly error-prone with advanced maternal age.
  2. Meiotic Chromosome Segregation in C. elegans
    Anne M Villeneuve; Fiscal Year: 2010
    ..of the plan are highly relevant to understanding how features of chromosome organization contribute to assembly and function of the female meiotic spindle, a process that becomes increasingly error-prone with advanced maternal age.
  3. MICRONUTRIENTS AND MOTHER TO CHILD TRANSMISSION OF HIV
    Richard Semba; Fiscal Year: 2001
    ..03). Vitamin A significantly reduced low birth weight in a multivariate analysis controlling for maternal age, body mass index, and CD4+ count...
  4. Clinical Measures to Lower Genital Tract Trauma at Birth
    Leah Albers; Fiscal Year: 2004
    ..three strategies on the likelihood of an intact perineum after birth, with control for confounding variables (maternal age and parity, birth position, style of pushing, size and position of baby at birth, length of second stage, and ..
  5. Maternal Morbidity and Mortality in Multiple Pregnancy
    Barbara Luke; Fiscal Year: 2006
    ..are limited, though, by their small sample sizes and frequent failure to control for the confounding factors of maternal age and parity...
  6. Plurality and Contemporary Infant Mortality Risks
    Barbara Luke; Fiscal Year: 2006
    ..Older maternal age requires more aggressive therapies to achieve a pregnancy, including transferring more embryos...
  7. Spontaneous Arousals in "CHIME" Infants at Risk for SIDS
    ROBERT DARNALL; Fiscal Year: 2006
    ..In addition, important demographic data were collected including maternal age, cigarette smoking, and alcohol use...
  8. Quasi-experimental studies of early risk factors for severe psychopathology
    Paul Lichtenstein; Fiscal Year: 2010
    ..risk for these severe problems, including maternal smoking during pregnancy, maternal stress during pregnancy, maternal age at childbearing, and advancing paternal age at childbearing...
  9. THE BIODEMOGRAPHY OF HUMAN LONGEVITY--A TRAINING PROGRAM
    Leonid Gavrilov; Fiscal Year: 2005
    ..importance of mutation load on the paternal X chromosome inherited by daughters only); (2) to analyze the maternal age effects on offspring longevity (in relation to the possible role of age-related accumulation of oxidative ..
  10. Advanced Reproductive Technology and Infant Health
    Marianne Bitler; Fiscal Year: 2005
    ..impacts of ART use and of state-mandated insurance coverage of infertility treatment on the number of births, maternal age at birth, and the incidence of multiple births, using both the NSFG and Vital Statistics birth certificate data;..
  11. CONTROL OF MEIOSIS AND GERMLINE PROLIFERATION
    DAVID I GREENSTEIN; Fiscal Year: 2010
    ..elegans will define the signaling mechanisms controlling late events in oogenesis and provide insights into how they may go awry when signaling is perturbed. ..
  12. CONTROL OF MEIOSIS AND GERMLINE PROLIFERATION
    David Greenstein; Fiscal Year: 2009
    ..elegans will define the signaling mechanisms controlling late events in oogenesis and provide insights into how they may go awry when signaling is perturbed. ..
  13. Age and molecular mechanisms contributing to aneuploidy in oocytes
    Richard Schultz; Fiscal Year: 2009
    ..Most aneuplodies associated with increased maternal age are due to non-disjunction and meiotic errors that occur during meiosis...
  14. Ectopic Pregnancy: Assessing Long-Term Trends in Rates and Risk Factors
    Delia Scholes; Fiscal Year: 2007
    ..EP rates may not be declining; and a number of important risk factors-including tubal sterilization, advanced maternal age and Chlamydia trachomatis and other asymptomatic sexually transmitted infections -have become increasingly ..
  15. DIET, IMMUNE MODULATION, AND ASTHMA IN EARLY LIFE
    Scott Weiss; Fiscal Year: 2002
    ..potentially influential host and environmental factors to be examined include: parental asthma history, maternal age, perinatal history, acute lower respiratory illness history, day care, environmental tobacco smoke, birthweight,..
  16. Advanced Reproductive Age and Environmental Health
    Stephanie Engel; Fiscal Year: 2007
    ..We propose to enroll 200 women of advanced maternal age (AMA) in a prospective pregnancy cohort, and to assemble a repository of maternal biological specimens ..
  17. Segregation of error-prone chromosomes in meiosis
    Dean S Dawson; Fiscal Year: 2010
    ..The incidence of conceptuses with inappropriate numbers of chromosomes rises with increased maternal age. Recombination between homologous chromosomes greatly increases the probability that they will segregate ..