maternal age

Summary

Summary: The age of the mother in PREGNANCY.

Top Publications

  1. ncbi Advanced maternal age. Part I: obstetric complications
    Ihab M Usta
    Department of Obstetrics and Gynecology, American University of Beirut Medical Center, Beirut, Lebanon
    Am J Perinatol 25:521-34. 2008
  2. doi Advanced maternal age and the risk of cesarean birth: a systematic review
    Hamideh Bayrampour
    Faculty of Nursing, University of Manitoba, Winnipeg, Manitoba, Canada
    Birth 37:219-26. 2010
  3. ncbi Advanced maternal age and adverse perinatal outcome
    Bo Jacobsson
    Perinatal Centre, Department of Obstetrics and Gynecology, Sahlgrenska University Hospital Ostra, S 416 85 Goteborg, Sweden
    Obstet Gynecol 104:727-33. 2004
  4. doi Demographic and medical consequences of the postponement of parenthood
    L Schmidt
    Section of Social Medicine, Department of Public Health, University of Copenhagen, Denmark
    Hum Reprod Update 18:29-43. 2012
  5. doi Advancing paternal age and risk of autism: new evidence from a population-based study and a meta-analysis of epidemiological studies
    C M Hultman
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
    Mol Psychiatry 16:1203-12. 2011
  6. pmc Maternal age and fetal loss: population based register linkage study
    A M Nybo Andersen
    Department of Epidemiology Research, Danish Epidemiology Science Centre, Statens Serum Institut, DK 2300 Copenhagen S, Denmark
    BMJ 320:1708-12. 2000
  7. ncbi The perinatal effects of delayed childbearing
    K S Joseph
    Perinatal Epidemiology Research Unit, Departments of Obstetrics and Gynaecology and Pediatrics, Dalhousie University, Halifax, Nova Scotia, Canada
    Obstet Gynecol 105:1410-8. 2005
  8. doi Caesarean section is associated with an increased risk of childhood-onset type 1 diabetes mellitus: a meta-analysis of observational studies
    C R Cardwell
    Department of Epidemiology and Public Health, School of Medicine and Dentistry, Queen s University Belfast, Grosvenor Road, Belfast, BT12 6BJ, UK
    Diabetologia 51:726-35. 2008
  9. doi Advanced maternal age and adverse perinatal outcome: a review of the evidence
    Mary Carolan
    Department of Nursing and Midwifery, University of Limerick, Ireland
    Midwifery 27:793-801. 2011
  10. pmc Prevalence of smoking during pregnancy and associated risk factors among Canadian women: a national survey
    Ban Al-Sahab
    School of Kinesiology and Health Science, York University, Toronto, ON Canada M3J 1P3
    BMC Pregnancy Childbirth 10:24. 2010

Detail Information

Publications350 found, 100 shown here

  1. ncbi Advanced maternal age. Part I: obstetric complications
    Ihab M Usta
    Department of Obstetrics and Gynecology, American University of Beirut Medical Center, Beirut, Lebanon
    Am J Perinatol 25:521-34. 2008
    More women are postponing pregnancy into the fourth and fifth decades of life for a variety of reasons. Advanced maternal age, traditionally defined as age more than 35 years, has been associated with increased obstetric morbidity and ..
  2. doi Advanced maternal age and the risk of cesarean birth: a systematic review
    Hamideh Bayrampour
    Faculty of Nursing, University of Manitoba, Winnipeg, Manitoba, Canada
    Birth 37:219-26. 2010
    The increasing pregnancy rate at advanced maternal age is contemporaneous with the increasing rate of cesarean birth. Several studies have found that advanced maternal age is a risk factor for cesarean birth...
  3. ncbi Advanced maternal age and adverse perinatal outcome
    Bo Jacobsson
    Perinatal Centre, Department of Obstetrics and Gynecology, Sahlgrenska University Hospital Ostra, S 416 85 Goteborg, Sweden
    Obstet Gynecol 104:727-33. 2004
    The aim of this study was to investigate the influence of maternal age on perinatal and obstetric outcome in women aged 40-44 years and those 45 years or older and to estimate whether adverse outcome was related to intercurrent illness ..
  4. doi Demographic and medical consequences of the postponement of parenthood
    L Schmidt
    Section of Social Medicine, Department of Public Health, University of Copenhagen, Denmark
    Hum Reprod Update 18:29-43. 2012
    ..Increasing public awareness of the impact of advanced female and male age on the reproductive outcome is essential for people to make well-informed decisions on when to start family formation...
  5. doi Advancing paternal age and risk of autism: new evidence from a population-based study and a meta-analysis of epidemiological studies
    C M Hultman
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
    Mol Psychiatry 16:1203-12. 2011
    ..26-3.88: P=0.006) more likely to have autism than offspring of men aged ≤29 years, after controlling for maternal age and documented risk factors for autism...
  6. pmc Maternal age and fetal loss: population based register linkage study
    A M Nybo Andersen
    Department of Epidemiology Research, Danish Epidemiology Science Centre, Statens Serum Institut, DK 2300 Copenhagen S, Denmark
    BMJ 320:1708-12. 2000
    To estimate the association between maternal age and fetal death (spontaneous abortion, ectopic pregnancy, stillbirth), taking into account a woman's reproductive history.
  7. ncbi The perinatal effects of delayed childbearing
    K S Joseph
    Perinatal Epidemiology Research Unit, Departments of Obstetrics and Gynaecology and Pediatrics, Dalhousie University, Halifax, Nova Scotia, Canada
    Obstet Gynecol 105:1410-8. 2005
    ....
  8. doi Caesarean section is associated with an increased risk of childhood-onset type 1 diabetes mellitus: a meta-analysis of observational studies
    C R Cardwell
    Department of Epidemiology and Public Health, School of Medicine and Dentistry, Queen s University Belfast, Grosvenor Road, Belfast, BT12 6BJ, UK
    Diabetologia 51:726-35. 2008
    ....
  9. doi Advanced maternal age and adverse perinatal outcome: a review of the evidence
    Mary Carolan
    Department of Nursing and Midwifery, University of Limerick, Ireland
    Midwifery 27:793-801. 2011
    To examine the evidence in relation to advanced maternal age (35-39 years), physiological risk and adverse perinatal outcome (stillbirth, low birth weight, preterm birth) in high-income countries.
  10. pmc Prevalence of smoking during pregnancy and associated risk factors among Canadian women: a national survey
    Ban Al-Sahab
    School of Kinesiology and Health Science, York University, Toronto, ON Canada M3J 1P3
    BMC Pregnancy Childbirth 10:24. 2010
    ..Therefore, the study aims to assess the prevalence of smoking during pregnancy and its associated risk factors throughout the Canadian provinces and territories...
  11. doi Assisted reproductive technologies (ART) in Canada: 2007 results from the Canadian ART Register
    Joanne Gunby
    Pegasus Technologies, Burlington, Ontario, Canada
    Fertil Steril 95:542-7.e1-10. 2011
    ..To present a report on assisted reproductive technologies (ART) cycles performed in 2007 in Canada and show trends in outcomes over time. This is the seventh annual report from the Canadian ART Register (CARTR)...
  12. doi The maternal age-specific live birth prevalence of trisomies 13 and 18 compared to trisomy 21 (Down syndrome)
    George M Savva
    Department of Public Health and Primary Care, University of Cambridge, Institute of Public Health, Cambridge, UK
    Prenat Diagn 30:57-64. 2010
    To estimate the maternal age-specific live birth prevalence (in the absence of prenatal diagnosis and selective termination) of trisomy 13 (Patau syndrome) and trisomy 18 (Edwards syndrome) and compare it with that of trisomy 21 (Down ..
  13. doi Pregnancy outcome at extremely advanced maternal age
    Yariv Yogev
    Department of Obstetrics and Gynecology, Perinatal Division, Helen Schneider Hospital for Women, Rabin Medical Center, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
    Am J Obstet Gynecol 203:558.e1-7. 2010
    The purpose of this study was to evaluate pregnancy outcome in women at extremely advanced maternal age (≥ 45 years).
  14. doi Comprehensive embryo analysis of advanced maternal age-related aneuploidies and mosaicism by short comparative genomic hybridization
    Mariona Rius
    Unitat de Biologia Cellular i Genetica Medica, Facultat de Medicina, Universitat Autonoma de Barcelona, Bellaterra, Spain
    Fertil Steril 95:413-6. 2011
    ..short-CGH) method was used to perform a comprehensive cytogenetic study of isolated blastomeres from advanced maternal age embryos, discarded after fluorescent in situ hybridization (FISH) preimplantation genetic screening (PGS), ..
  15. ncbi Transcriptomic profiling of human oocytes: association of meiotic aneuploidy and altered oocyte gene expression
    E Fragouli
    Nuffield Department of Obstetrics and Gynaecology, University of Oxford, Oxford, UK
    Mol Hum Reprod 16:570-82. 2010
    ..Aneuploidy is also closely related with advancing maternal age, a phenomenon not well understood...
  16. ncbi Cumulative incidence of type 1 diabetes in 10,168 siblings of Finnish young-onset type 1 diabetic patients
    Valma Harjutsalo
    Diabetes and Genetic Epidemiology Unit, Department of Epidemiology and Health Promotion, National Public Health Institute, Mannerheimintie 166, FIN 00300, Helsinki, Finland
    Diabetes 54:563-9. 2005
    ..This large prospective family study of type 1 diabetes in siblings of childhood-onset diabetic patients provides reliable empirical estimates for the sibling recurrence risk...
  17. pmc Multiple meiotic errors caused by predivision of chromatids in women of advanced maternal age undergoing in vitro fertilisation
    Alan H Handyside
    London Bridge Fertility, Gynaecology and Genetics Centre, London, UK
    Eur J Hum Genet 20:742-7. 2012
    ..live births following both natural conception and in vitro fertilisation (IVF) and increases exponentially with maternal age in the decade preceding the menopause...
  18. doi Advancing maternal age is associated with increasing risk for autism: a review and meta-analysis
    Sven Sandin
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, PO Box 281, SE 171 77 Stockholm, Sweden
    J Am Acad Child Adolesc Psychiatry 51:477-486.e1. 2012
    We conducted a meta-analysis of epidemiological studies investigating the association between maternal age and autism.
  19. pmc Polar body array CGH for prediction of the status of the corresponding oocyte. Part I: clinical results
    Joep Geraedts
    Department of Genetics and Cell Biology, Research Institute GROW, Faculty of Health, Medicine and Life Sciences, Maastricht University, PO Box 5800, Maastricht, AZ 6202, The Netherlands
    Hum Reprod 26:3173-80. 2011
    ..e. PGS by polar body (PB) biopsy, with whole genome amplification and microarray-based comparative genomic hybridization (array CGH) analysis...
  20. ncbi Perinatal factors and the development of autism: a population study
    Emma J Glasson
    Schools of Population Health and Psychiatry and Clinical Neurosciences, University of Western Australia, Crawley, Australia
    Arch Gen Psychiatry 61:618-27. 2004
    ..Some investigations have shown an association with obstetric complications but findings have been inconsistent owing to differences in sampling and methods...
  21. pmc Late age at first full term birth is strongly associated with lobular breast cancer
    Polly A Newcomb
    University of Wisconsin Carbone Comprehensive Cancer Center, Madison, Wisconsin, USA
    Cancer 117:1946-56. 2011
    ..Late age at first full-term birth and nulliparity are known to increase breast cancer risk. The frequency of these risk factors has increased in recent decades...
  22. doi Epidemiology of congenital anomalies in a population-based birth registry in Taiwan, 2002
    Bing Yu Chen
    Institute of Occupational Medicine and Industrial Hygiene, College of Public Health, National Taiwan University, Taipei 100, Taiwan
    J Formos Med Assoc 108:460-8. 2009
    ..We used the medical-practitioner-reported birth registry in 2002 to determine the occurrence of individual congenital anomalies and their associated risk factors, such as maternal age, fetal sex, and plurality.
  23. pmc Maternal smoking in pregnancy, fetal development, and childhood asthma
    Jouni J K Jaakkola
    Institute of Occupational Health, The University of Birmingham, Birmingham, United Kingdom
    Am J Public Health 94:136-40. 2004
    ..We examined the relationships among maternal smoking in pregnancy, fetal development, and the risk of asthma in childhood...
  24. ncbi Maternal characteristics and lifestyle factors and the risk of delivering high birth weight infants
    Janne Ørskou
    Perinatal Epidemiological Research Unit, Department of Obstetrics and Gynaecology, Aarhus University Hospital, Aarhus, Denmark
    Obstet Gynecol 102:115-20. 2003
    ....
  25. ncbi Advancing paternal age and autism
    Abraham Reichenberg
    Department of Psychiatry and Seaver Center for Autism Research, Mount Sinai School of Medicine, One Gustave L Levy Place, New York, NY 10029, USA
    Arch Gen Psychiatry 63:1026-32. 2006
    ..Maternal and paternal ages are associated with neurodevelopmental disorders...
  26. doi Advanced maternal age and risk of antepartum and intrapartum stillbirth
    Hamisu M Salihu
    Department of Epidemiology and Biostatistics, University of South Florida, Tampa, Florida, USA
    J Obstet Gynaecol Res 34:843-50. 2008
    ..We sought to assess the risk of antepartum and intrapartum stillbirth subtypes among women of advanced age...
  27. doi Paternal age at birth and high-functioning autistic-spectrum disorder in offspring
    Kenji J Tsuchiya
    Osaka Hamamatsu Joint Research Center for Child Mental Development OHJRC CMD, Hamamatsu University School of Medicine, Hamamatsu 431 3192, Japan
    Br J Psychiatry 193:316-21. 2008
    ..Previous studies have reported the association between advanced paternal age at birth and the risk of autistic-spectrum disorder in offspring, including offspring with intellectual disability...
  28. ncbi Consanguinity and advanced maternal age as risk factors for reproductive losses in Alexandria, Egypt
    M M Mokhtar
    Department of Huiman Genetics, Medical Research Institute, Alexandria University, Egypt
    Eur J Epidemiol 17:559-65. 2001
    ..This study aimed at delineating the role of consanguinity and advanced maternal age on reproductive losses in Alexandria, Egypt...
  29. ncbi Associations of parental, birth, and early life characteristics with systolic blood pressure at 5 years of age: findings from the Mater-University study of pregnancy and its outcomes
    Debbie A Lawlor
    Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Rd, Bristol, BS8 2PR, UK
    Circulation 110:2417-23. 2004
    ..We examined the associations of a range of parental and early life characteristics with systolic blood pressure at 5 years of age...
  30. pmc The effect of maternal anthropometric characteristics and social factors on gestational age and birth weight in Sudanese newborn infants
    Eltahir M Elshibly
    Clinic of Neonatology Campus Charité Mitte, Universitatsmedizin Berlin, Germany
    BMC Public Health 8:244. 2008
    ..The aim of this study was to quantify the effect of maternal anthropometry, education and socio-economic status on gestational age and birth weight...
  31. ncbi Comparison of models of maternal age-specific risk for Down syndrome live births
    J K Morris
    Department of Environmental and Preventive Medicine, Wolfson Institute of Preventive Medicine, St Bartholomew s and the Royal London School of Medicine and Dentistry, Charterhouse Square, London EC1M 6BQ, UK
    Prenat Diagn 23:252-8. 2003
    To display and compare the different published formulae that specify the association between maternal age and the risk of a Down syndrome live birth.
  32. ncbi Trends in mode of delivery during 1984-2003: can they be explained by pregnancy and delivery complications?
    C M O'Leary
    Telethon Institute for Child Health Research, Centre for Child Health Research, The University of Western Australia, West Perth, Western Australia, Australia
    BJOG 114:855-64. 2007
    ..To describe trends in mode of delivery, to identify significant factors which affected mode of delivery, and to describe how these factors and their impact have changed over time...
  33. pmc SNP microarray-based 24 chromosome aneuploidy screening demonstrates that cleavage-stage FISH poorly predicts aneuploidy in embryos that develop to morphologically normal blastocysts
    L E Northrop
    Reproductive Medicine Associates of New Jersey, Morristown, NJ 07960, USA
    Mol Hum Reprod 16:590-600. 2010
    ..These findings support the conclusion that cleavage-stage FISH technology is poorly predictive of aneuploidy in morphologically normal blastocysts...
  34. ncbi Impact of maternal age on obstetric outcome
    Jane Cleary-Goldman
    Columbia University Medical Center, New York, New York, USA
    Obstet Gynecol 105:983-90. 2005
    To estimate the effect of maternal age on obstetric outcomes.
  35. ncbi Maternal age and malformations in singleton births
    L M Hollier
    Department of Obstetrics and Gynecology, University of Texas Southwestern Medical Center, Dallas, Texas, USA
    Obstet Gynecol 96:701-6. 2000
    To examine the effect of maternal age on incidence of nonchromosomal fetal malformations.
  36. ncbi Pregnancy outcome at age 40 and older
    S Ziadeh
    Arch Gynecol Obstet 265:30-3. 2001
    ..Our purpose was to examine pregnancy outcomes among women age 40 or older...
  37. pmc Optimal fetal growth for the Caucasian singleton and assessment of appropriateness of fetal growth: an analysis of a total population perinatal database
    Eve M Blair
    Centre for Child Health Research, The University of Western Australia, at the Telethon Institute for Child Health Research, P, O, Box 855, West Perth, WA, 6872, Australia
    BMC Pediatr 5:13. 2005
    ..Appropriateness of growth can then be inferred from the ratio of the value of the observed dimension to that of the optimal dimension...
  38. ncbi Elective induction of labor as a risk factor for cesarean delivery among low-risk women at term
    A S Maslow
    Department of Clinical Outcomes and Quality Improvement, Franciscan Health System, Tacoma, Washington, USA
    Obstet Gynecol 95:917-22. 2000
    ..To determine the effects of elective induction on the risk of cesarean delivery in a cohort of women with low-risk term pregnancies and to evaluate the costs of elective induction services within our hospital system...
  39. ncbi Factors influencing childbearing decisions and knowledge of perinatal risks among Canadian men and women
    Suzanne Tough
    Faculty of Medicine, University of Calgary, Room C4 301, 2888 Shaganappi Trail NW, Calgary, AB, T3B 6A8, Canada
    Matern Child Health J 11:189-98. 2007
    ..Little is known about men's and women's understanding of the maternal age related risks to pregnancy.
  40. doi Modifiable maternal exposures and offspring blood pressure: a review of epidemiological studies of maternal age, diet, and smoking
    Marie Jo A Brion
    Department of Social Medicine, University of Bristol, Bristol BS8 2PR, United Kingdom
    Pediatr Res 63:593-8. 2008
    ..The results of studies of maternal age varied and there was strong evidence of heterogeneity in the pooled analysis...
  41. ncbi Recombination rate and reproductive success in humans
    Augustine Kong
    deCODE Genetics, Sturlugata 8, IS 101 Reykjavik, Iceland
    Nat Genet 36:1203-6. 2004
    ..meioses each, and found a positive correlation between maternal recombination counts of an offspring and maternal age. We postulated that the recombination rate of eggs does not increase with maternal age, but that the apparent ..
  42. ncbi To err (meiotically) is human: the genesis of human aneuploidy
    T Hassold
    Department of Genetics, Case Western Reserve University, 10, 900 Euclid Avenue, Cleveland, Ohio 44106, USA
    Nat Rev Genet 2:280-91. 2001
    ..However, recent molecular and cytogenetic approaches are now beginning to shed light on the non-disjunctional processes that lead to aneuploidy...
  43. ncbi Paternal age and intelligence: implications for age-related genomic changes in male germ cells
    Dolores Malaspina
    New York State Psychiatric Institute and Columbia University, New York, NY 10032, USA
    Psychiatr Genet 15:117-25. 2005
    ..There are also substantial genetic influences on intelligence, so de novo genetic events in male germ cells, which accompany advancing paternal age, may plausibly influence offspring intelligence...
  44. ncbi Comparison of obstetric outcomes in recipients of donor oocytes vs. women of advanced maternal age with autologous oocytes
    Melinda B Henne
    Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, Stanford University School of Medicine, Stanford, California, USA
    J Reprod Med 52:585-90. 2007
    To evaluate obstetric complications in women conceiving with donated oocytes as compared to controls of advanced maternal age.
  45. pmc Advanced maternal age: are decisions about the timing of child-bearing a failure to understand the risks?
    Karen M Benzies
    Faculty of Nursing, University of Calgary, Calgary, Alta
    CMAJ 178:183-4. 2008
  46. doi Age at first birth, mode of conception and psychological wellbeing in pregnancy: findings from the parental age and transition to parenthood Australia (PATPA) study
    C A McMahon
    Centre for Emotional Health, Department of Psychology, Macquarie University, Sydney, NSW 2109, Australia
    Hum Reprod 26:1389-98. 2011
    ..We aimed to describe the context of pregnancy for first-time mothers of different ages and examine relationships among maternal age at first birth, mode of conception and psychosocial wellbeing in pregnancy.
  47. doi A cost-effectiveness analysis of in-vitro fertilization by maternal age and number of treatment attempts
    Alison Griffiths
    NHMRC Clinical Trials Centre, The University of Sydney, Camperdown, NSW 2050, Australia
    Hum Reprod 25:924-31. 2010
    ..A decision analytic model was designed to estimate the incremental cost-effectiveness of IVF by additional treatment programmes and maternal age.
  48. doi Paternal age at birth of first child and risk of schizophrenia
    Liselotte Petersen
    National Centre for Register Based Research, Aarhus University, Denmark
    Am J Psychiatry 168:82-8. 2011
    ..The authors aimed to distinguish between these two measures of paternal age...
  49. pmc Age-dependent recombination rates in human pedigrees
    Julie Hussin
    Department of Biochemistry, Faculty of Medicine, University of Montreal, Montreal, Canada
    PLoS Genet 7:e1002251. 2011
    In humans, chromosome-number abnormalities have been associated with altered recombination and increased maternal age. Therefore, age-related effects on recombination are of major importance, especially in relation to the mechanisms ..
  50. pmc Autism and intellectual disability are differentially related to sociodemographic background at birth
    Helen Leonard
    Telethon Institute for Child Health Research, Centre for Child Health Research, The University of Western Australia, West Perth, Western Australia, Australia
    PLoS ONE 6:e17875. 2011
    ..Research findings investigating the sociodemographics of autism spectrum disorder (ASD) have been inconsistent and rarely considered the presence of intellectual disability (ID)...
  51. doi Development of heart block in children of SSA/SSB-autoantibody-positive women is associated with maternal age and displays a season-of-birth pattern
    Aurelie Ambrosi
    Department of Medicine, Karolinska Institutet, Stockholm, Sweden
    Ann Rheum Dis 71:334-40. 2012
    ..The authors investigated the influence of other maternal and fetal factors on heart block development in a Swedish population-based cohort...
  52. ncbi Trends and geographic inequalities in the prevalence of Down syndrome in Europe, 1980-1999
    H Dolk
    EUROCAT Central Registry, Room 15E12, Faculty of Life and Health Sciences, University of Ulster at Jordanstown, Shore Rd, Newtownabbey BT37 OQB, Ulster, UK
    Rev Epidemiol Sante Publique 53:2S87-95. 2005
    ..In this paper, we aim to examine trends in the live birth prevalence of Down syndrome in Europe in the light of trends in maternal age and in prenatal diagnosis.
  53. ncbi Advanced maternal age--how old is too old?
    Linda J Heffner
    Department of Obstetrics and Gynecology, Boston University School of Medicine, Boston, USA
    N Engl J Med 351:1927-9. 2004
  54. pmc Temporal changes in key maternal and fetal factors affecting birth outcomes: a 32-year population-based study in an industrial city
    Svetlana V Glinianaia
    Institute of Health and Society, Newcastle University, William Leech Building, The Medical School, Framlington Place, Newcastle upon Tyne, NE2 4HH, UK
    BMC Pregnancy Childbirth 8:39. 2008
    ..The objective of this study was to describe temporal changes in key maternal and fetal factors affecting birth outcomes in Newcastle upon Tyne over three decades, 1961-1992...
  55. pmc Maternal age and chromosomally abnormal pregnancies: what we know and what we wish we knew
    Terry Hassold
    School of Molecular Biosciences and Center for Reproductive Biology, Washington State University, Pullman, Washington 99164, USA
    Curr Opin Pediatr 21:703-8. 2009
    The relationship between increasing maternal age and trisomy has been recognized for over 50 years and is one of the most important etiological factors associated with any human genetic disorder...
  56. doi Gestational age, birth weight, and risk for injuries in childhood
    Yuelian Sun
    Department of Epidemiology, Institute of Public Health, University of Aarhus, Aarhus, Denmark
    Epidemiology 21:650-7. 2010
    ..Most injury studies have focused on proximal causes; few have examined the role of neonatal characteristics such as birth weight and gestational age...
  57. doi Pregnancy outcomes for nulliparous women of advanced maternal age in South Australia, 1998-2008
    Isobel Ludford
    Office of Public Health, Department for Health and Ageing, 11 Hindmarsh Square, Adelaide, SA 5000, Australia
    Aust N Z J Obstet Gynaecol 52:235-41. 2012
    ..Child bearing in the later reproductive years has become increasingly common in Australia with potential implications for clinical practice...
  58. doi Assisted reproductive technologies in Canada: 2005 results from the Canadian Assisted Reproductive Technologies Register
    Joanne Gunby
    Pegasus Technologies, Burlington, Ontario, Canada
    Fertil Steril 91:1721-30. 2009
    ..To present a report on assisted reproductive technologies (ART) cycles performed in 2005 in Canada. This is the fifth annual report from the Canadian ART Register (CARTR)...
  59. pmc Parental ages and levels of DNA methylation in the newborn are correlated
    Ronald M Adkins
    Department of Pediatrics, University of Tennessee Health Science Center, Memphis, TN 38103, USA
    BMC Med Genet 12:47. 2011
    ..Only a proportion of these increased risks among the children of older parents can be attributed to nondisjunction and chromosomal rearrangements...
  60. doi A significant linear association exists between advanced maternal age and adverse perinatal outcome
    Shimrit Salem Yaniv
    Department of Obstetrics and Gynecology, Soroka University Medical Center, P O Box 151, Beersheba, Israel
    Arch Gynecol Obstet 283:755-9. 2011
    ..The present study was aimed to investigate perinatal outcome of elderly nulliparous patients...
  61. doi Maternal age effect on the development of Prader-Willi syndrome resulting from upd(15)mat through meiosis 1 errors
    Keiko Matsubara
    Department of Molecular Endocrinology, National Research Institute for Child Health and Development, 2 10 1 Ohkura, Setagaya, Tokyo, Japan
    J Hum Genet 56:566-71. 2011
    ..Of these factors involved in the development of upd(15)mat, M1 non-disjunction is a maternal age-dependent phenomenon...
  62. doi Effect of maternal age on mitochondrial DNA copy number, ATP content and IVF outcome of bovine oocytes
    Hisataka Iwata
    Tokyo University of Agriculture, Funako 1737, Atugi City 243 0034, Japan
    Reprod Fertil Dev 23:424-32. 2011
    The primary aim of the present study was to examine the effect of maternal age (in months) on mitochondrial DNA copy number (Mt number), ATP content and IVF outcome of bovine oocytes...
  63. ncbi Obstetric outcomes in donor oocyte pregnancies compared with advanced maternal age in in vitro fertilization pregnancies
    Sacha A Krieg
    Department of Obstetrics and Gynecology, Stanford University School of Medicine, Stanford, California, USA
    Fertil Steril 90:65-70. 2008
    ..To evaluate obstetric complications in women who conceived through donated oocytes compared with women who conceived through assisted reproduction using autologous oocytes...
  64. doi Defective deacetylation of histone 4 K12 in human oocytes is associated with advanced maternal age and chromosome misalignment
    I M van den Berg
    Department of Obstetrics and Gynaecology, Subdivision of Reproductive Medicine, Erasmus Medical Centre, Rotterdam, The Netherlands
    Hum Reprod 26:1181-90. 2011
    ..meiosis are associated with low fertility in humans and the incidence of these errors increases with advancing maternal age. Studies of mitosis and meiosis suggest that defective remodeling of chromatin plays a causative role in ..
  65. ncbi Can assisted reproduction technology compensate for the natural decline in fertility with age? A model assessment
    Henri Leridon
    U569 Epidemiology, demography and social sciences IFR69, INSERM French Institute of Health and Medical Research and INED National Institute for Demographic Studies
    Hum Reprod 19:1548-53. 2004
    b>Maternal age is an important factor in reproduction. Can assisted reproduction technologies (ART) fully compensate for the decline in fertility with age?
  66. pmc Twenty-year trends in the prevalence of Down syndrome and other trisomies in Europe: impact of maternal age and prenatal screening
    Maria Loane
    Institute of Nursing Research, University of Ulster, Jordanstown, UK
    Eur J Hum Genet 21:27-33. 2013
    ..differences in total and live birth prevalence of trisomies 21, 18 and 13 with regard to increasing maternal age and prenatal diagnosis in Europe. Twenty-one population-based EUROCAT registries covering 6...
  67. ncbi Fetal death
    Robert M Silver
    Department of Obstetrics and Gynecology, University of Utah, Salt Lake City, UT 84132, USA
    Obstet Gynecol 109:153-67. 2007
    ..Risk factors for fetal death include African American race, advanced maternal age, obesity, smoking, prior fetal death, maternal diseases, and fetal growth impairment...
  68. pmc Maternal age, multiple birth, and extremely low birth weight infants
    Betty R Vohr
    Department of Pediatrics, The Warren Alpert Medical School of Brown University, Providence, RI, USA
    J Pediatr 154:498-503.e2. 2009
    ..To compare the rates of adverse neurodevelopmental outcome or death at 18 to 22 months among extremely low birth weight (ELBW) infants born to mothers >or=4 0 years to the corresponding rates among infants of younger mothers...
  69. pmc Racial differences in gene-specific DNA methylation levels are present at birth
    Ronald M Adkins
    University of Tennessee Health Science Center, Memphis, TN 48103, USA
    Birth Defects Res A Clin Mol Teratol 91:728-36. 2011
    ..The origin of these differences is inadequately understood, and this is a question of specific relevance to childhood and adult cancer...
  70. doi Validation of microarray comparative genomic hybridization for comprehensive chromosome analysis of embryos
    Cristina Gutiérrez-Mateo
    Reprogenetics, Livingston, New Jersey, USA
    Fertil Steril 95:953-8. 2011
    ..To validate and determine the best array-comparative genomic hybridization (aCGH; array-CGH) protocols for preimplantation genetic screening (PGS)...
  71. doi Monozygotic twinning associated with assisted reproductive technologies: a review
    K I Aston
    Andrology and IVF Laboratories, Department of Surgery, University of Utah School of Medicine, Salt Lake City, Utah 84108, USA
    Reproduction 136:377-86. 2008
    ..birth rates have increased markedly in developed countries since the 1970s for two primary reasons: increasing maternal age and the advent and increasing use of fertility treatments...
  72. doi Young maternal age and risk of intrapartum stillbirth
    Ronee E Wilson
    Department of Epidemiology and Biostatistics, University of South Florida, Tampa, FL, USA
    Arch Gynecol Obstet 278:231-6. 2008
    ..To determine the risk of intrapartum stillbirth among teen mothers...
  73. pmc The effect of delaying childbirth on primary cesarean section rates
    Gordon C S Smith
    Department of Obstetrics and Gynaecology, Cambridge University, The Rosie Hospital, Cambridge, United Kingdom
    PLoS Med 5:e144. 2008
    ..The aims of the present study were (1) to characterize the association between maternal age and the outcome of labor, (2) to determine the proportion of the increase in primary cesarean rates that could ..
  74. ncbi Influence of thyroid autoimmunity and maternal age on the risk of miscarriage
    Lino Sieiro Netto
    Faculdade de Medicina Serviços de Endocrinologia, HUCFF, UFRJ, Rio de Janeiro, Brazil
    Am J Reprod Immunol 52:312-6. 2004
    ..Another point to be considered is the association of high risk of abortion and maternal age. The aim of the present study was to evaluate if the association between TAI and miscarriage could also be ..
  75. ncbi Risk of autism and increasing maternal and paternal age in a large north American population
    Judith K Grether
    Environmental Health Investigations Branch, California Department of Public Health, Richmond, California 94804, USA
    Am J Epidemiol 170:1118-26. 2009
    ..In adjusted models that included age of the other parent and demographic covariates, a 10-year increase in maternal age was associated with a 38% increase in the odds ratio for autism (odds ratio = 1.38, 95% confidence interval: 1...
  76. pmc Estimated autism risk and older reproductive age
    Marissa D King
    Institute for Social and Economic Research and Policy, Columbia University, New York, NY 10027, USA
    Am J Public Health 99:1673-9. 2009
    ..We sought to estimate the risk for autism associated with maternal and paternal age across successive birth cohorts...
  77. doi Maternal age and paternal age are associated with distinct childhood behavioural outcomes in a general population birth cohort
    Sukanta Saha
    Queensland Centre for Mental Health Research, The Park Centre for Mental Health, Locked Bag 500, Richlands Q4077, Australia
    Schizophr Res 115:130-5. 2009
    ..The aim of the study was to examine the relationship between paternal and maternal ages and selected behavioural measures in children using a large birth cohort...
  78. pmc Evidence that a defective spindle assembly checkpoint is not the primary cause of maternal age-associated aneuploidy in mouse eggs
    Francesca E Duncan
    Department of Biology, University of Pennsylvania, Philadelphia, Pennsylvania, USA
    Biol Reprod 81:768-76. 2009
    Advanced maternal age is unequivocally associated with increased aneuploidy in human eggs and infertility, but the molecular basis for this phenomenon is unknown...
  79. ncbi Chromosome mosaicism in cleavage-stage human embryos: evidence of a maternal age effect
    Santiago Munne
    Institute for Reproductive Medicine and Science, Saint Barnabas Medical Centre, Livingston, NJ 07052, USA
    Reprod Biomed Online 4:223-32. 2002
    ..While overall mosaicism did not increase with maternal age, the average maternal age of the embryos that had mosaics caused by mitotic non-disjunction was significantly ..
  80. ncbi Is pregnancy over 45 with very high parity related with adverse maternal and fetal outcomes?
    A Kale
    Department of Obstetrics and Gynecology, Dicle University School of Medicine, Diyarbakir, Turkey
    Clin Exp Obstet Gynecol 36:120-2. 2009
    ..To examine whether very high parity and age over 45 years are related with adverse maternal and fetal outcomes...
  81. ncbi Trends in the occurrence, determinants, and consequences of multiple births
    Beatrice Blondel
    Epidemiological Research Unit on Perinatal and Women s Health, Institut National de la Sante et de la Recherche Medicale INSERM, Villejuif, France
    Semin Perinatol 26:239-49. 2002
    ..to one third of the increase in twin or triplet pregnancies are attributable to a contemporaneous increase in maternal age. Furthermore, in countries with high occurrence of multiple births, 30% to 50% of twin pregnancies and at least ..
  82. pmc Effect of Body Mass Index on pregnancy outcomes in nulliparous women delivering singleton babies
    Sohinee Bhattacharya
    Dugald Baird Centre for Research on Women s Health, Aberdeen Maternity Hospital, Aberdeen, UK
    BMC Public Health 7:168. 2007
    ..In a population based cohort study, using routinely collected data, this paper examines the effect of increasing Body Mass Index (BMI) on pregnancy outcomes in nulliparous women delivering singleton babies...
  83. ncbi Maternal and birth characteristics in relation to childhood leukaemia
    Danise Podvin
    Department of Epidemiology, School of Public Health and Community Medicine, University of Washington, Seattle, 98195, USA
    Paediatr Perinat Epidemiol 20:312-22. 2006
    ..b>Maternal age 35+ years (odds ratio [OR] 1.5; 95% confidence interval [CI] 1.1, 2.0), infant birthweight 4,000+ g (OR 1...
  84. ncbi Dystocia increases with advancing maternal age
    Ann Treacy
    National Maternity Hospital, Dublin, Ireland
    Am J Obstet Gynecol 195:760-3. 2006
    The purpose of this study was to assess the influence of maternal age on obstetric indices of uterine efficiency in spontaneous nulliparous labor managed according to a standardized protocol in order to determine whether increasing ..
  85. ncbi Cesarean birth in the United States: epidemiology, trends, and outcomes
    Marian F MacDorman
    Reproductive Statistics Branch, Division of Vital Statistics, National Center for Health Statistics, Centers for Disease Control and Prevention, 3311 Toledo Road, Room 7318, Hyattsville, MD 20782, USA
    Clin Perinatol 35:293-307, v. 2008
    ..Several studies note an increased risk for neonatal and maternal mortality for medically elective cesareans compared with vaginal births...
  86. ncbi Longitudinal reference ranges for estimated fetal weight
    Synnøve Lian Johnsen
    Department of Obstetrics and Gynecology, Haukeland University Hospital, Bergen, Norway
    Acta Obstet Gynecol Scand 85:286-97. 2006
    ..The aims of the present study were to establish reference ranges for the growth of estimated fetal weight (EFW) between gestational weeks 20 and 42 and to determine the effect of fetal and maternal factors...
  87. doi Does young maternal age increase the risk of adverse obstetric, fetal and neonatal outcomes: a cohort study
    Claire M de Vienne
    Department of Obstetrics and Gynecology, University Hospital of Caen, France
    Eur J Obstet Gynecol Reprod Biol 147:151-6. 2009
    To determine whether young maternal age is associated with increased risks of adverse obstetric, fetal and perinatal outcomes.
  88. pmc Maternal age and risk of stillbirth: a systematic review
    Ling Huang
    Health Surveillance and Epidemiology Division, Centre for Health Promotion, Public Health Agency of Canada, Ottawa, Ont
    CMAJ 178:165-72. 2008
    ..Studies regarding the relation between older maternal age and the risk of stillbirth have yielded inconsistent conclusions...
  89. ncbi Early infant feeding and risk of type 1 diabetes mellitus-a nationwide population-based case-control study in pre-school children
    J Rosenbauer
    Institute of Biometrics and Epidemiology, German Diabetes Centre, Leibniz Institute at Heinrich Heine University Düsseldorf, Germany uni duesseldorf de
    Diabetes Metab Res Rev 24:211-22. 2008
    ..Reducing potential bias and the variety of exposures, we investigated the association between type 1 diabetes risk and nutritional and environmental exposures in pre-school children...
  90. ncbi Restricted fetal growth in sudden intrauterine unexplained death
    J Frederik Frøen
    Department of Obstetrics and Gynecology, Rikshospitalet University Clinic, University of Oslo, Oslo, Norway
    Acta Obstet Gynecol Scand 83:801-7. 2004
    ....
  91. ncbi Surveillance of cesarean section deliveries, New Jersey, 1999-2004
    Charles E Denk
    Maternal and Child Health Epidemiology Program, New Jersey Department of Health and Senior Services, Trenton, New Jersey08625 0364, USA
    Birth 33:203-9. 2006
    ..Nationally and in New Jersey, the cesarean delivery rate has been increasing steadily for nearly a decade, and especially since 1999. The purpose of this study was to describe recent trends in cesarean section delivery in New Jersey...
  92. ncbi Paternal age and maternal age are risk factors for miscarriage; results of a multicentre European study
    Elise de La Rochebrochard
    INED National Demographic Studies Institute, 75020 Paris, France
    Hum Reprod 17:1649-56. 2002
    It is well known that miscarriage risk increases with age. However, studies usually investigate only maternal age effects...
  93. ncbi Association between maternal age and the likelihood of a cesarean section: a population-based multivariate logistic regression analysis
    Herng Ching Lin
    School of Health Care Administration, Taipei Medical University, Taipei, Taiwan
    Acta Obstet Gynecol Scand 83:1178-83. 2004
    A majority of studies examining the relationship between advancing maternal age and the likelihood of cesarean section (CS) use data from regional samples or from a limited number of medical institutions...
  94. ncbi Maternal age and the risk of stillbirth throughout pregnancy in the United States
    Uma M Reddy
    Pregnancy and Perinatology Branch, National Institute of Child Health and Human Development, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, USA
    Am J Obstet Gynecol 195:764-70. 2006
    The objective of the study was to examine the relationship of maternal age with stillbirth risk throughout gestation.
  95. doi Trends in maternal obesity and associated risks of adverse pregnancy outcomes in a population of Chinese women
    T Y Leung
    Department of Obstetrics and Gynaecology, The Chinese University of Hong Kong, Hong Kong, China
    BJOG 115:1529-37. 2008
    ..To assess the effect of increasing body mass index (BMI) on pregnancy outcome in a population of Chinese women...
  96. ncbi Indications for cesarean deliveries in Norway
    Toril Kolås
    Department of Obstetrics and Gynecology, Lillehammer County Hospital, Norway
    Am J Obstet Gynecol 188:864-70. 2003
    ..The purpose of this study was to investigate the indications for cesarean deliveries in Norway, related to type of operation, parity, and gestational age...
  97. ncbi Registration of Down syndrome in the Medical Birth Registry of Norway: validity and time trends
    Kari Klungsøyr Melve
    Department of Public Health and Primary Health Care, University of Bergen, Bergen, Norway
    Acta Obstet Gynecol Scand 87:824-30. 2008
    ..To validate Down syndrome registration in the Medical Birth Registry of Norway (MBRN), 2001-2005, and study time trends and geographical differences in Down syndrome prevalence,1967-2005...
  98. ncbi Trends in birth size and macrosomia in Queensland, Australia, from 1988 to 2005
    Petra H Lahmann
    The University of Queensland, School of Population Health, Herston Qld, Australia
    Paediatr Perinat Epidemiol 23:533-41. 2009
    ..Recorded birthweight (BW, g), birth length (BL, cm), gestational age (weeks), maternal age, ethnic origin and calculated ponderal index (PI, kg/m(3)) were used...
  99. doi Increased risks of neonatal and postneonatal mortality associated with teenage pregnancy had different explanations
    Xi Kuan Chen
    OMNI Research Group, Department of Obstetrics and Gynecology, University of Ottawa, Ottawa, Ontario, Canada K1H 8L6
    J Clin Epidemiol 61:688-94. 2008
    ..To determine the potential pathway of the association between teenage pregnancy and neonatal and postneonatal mortality...
  100. pmc Socioeconomic factors and adolescent pregnancy outcomes: distinctions between neonatal and post-neonatal deaths?
    Barry P Markovitz
    Saint Louis University School of Public Health, St, Louis, Missouri, USA
    BMC Public Health 5:79. 2005
    Young maternal age has long been associated with higher infant mortality rates, but the role of socioeconomic factors in this association has been controversial...

Research Grants73

  1. Genome-wide recombination as a risk factor for nondisjunction
    NATASHA D HOLLIS; Fiscal Year: 2010
    ..It has been shown that altered patterns of recombination and maternal age are risk factors for nondisjunction...
  2. Genome-wide recombination as a risk factor for nondisjunction
    NATASHA HOLLIS; Fiscal Year: 2009
    ..It has been shown that altered patterns of recombination and maternal age are risk factors for nondisjunction...
  3. High Density Lipoprotein (HDL) in Follicular Fluid and Fertility Outcomes
    VICTOR YUTAKA FUJIMOTO; Fiscal Year: 2010
    ..Given the societal dilemma of reproductive choice with advanced maternal age resulting in the infertile condition together with the increasing evidence that environmental exposures ..
  4. Meiotic Chromosome Segregation in C. elegans
    Anne Villeneuve; Fiscal Year: 2009
    ..of the plan are highly relevant to understanding how features of chromosome organization contribute to assembly and function of the female meiotic spindle, a process that becomes increasingly error-prone with advanced maternal age.
  5. Meiotic Chromosome Segregation in C. elegans
    Anne M Villeneuve; Fiscal Year: 2010
    ..of the plan are highly relevant to understanding how features of chromosome organization contribute to assembly and function of the female meiotic spindle, a process that becomes increasingly error-prone with advanced maternal age.
  6. WNV Infection and Outcomes of Pregnancy in Humans
    Dawn Wesson; Fiscal Year: 2005
    ..as WNV-infected women and matched for key potential confounders, which are zip code or hospital of delivery and maternal age. Cases and controls will be followed up, and information regarding maternal, newborn, and infant outcomes will ..
  7. WNV Infection and Outcomes of Pregnancy in Humans
    Dawn Wesson; Fiscal Year: 2004
    ..as WNV-infected women and matched for key potential confounders, which are zip code or hospital of delivery and maternal age. Cases and controls will be followed up, and information regarding maternal, newborn, and infant outcomes will ..
  8. WNV Infection and Outcomes of Pregnancy in Humans
    Dawn Wesson; Fiscal Year: 2006
    ..as WNV-infected women and matched for key potential confounders, which are zip code or hospital of delivery and maternal age. Cases and controls will be followed up, and information regarding maternal, newborn, and infant outcomes will ..
  9. MICRONUTRIENTS AND MOTHER TO CHILD TRANSMISSION OF HIV
    Richard Semba; Fiscal Year: 2000
    ..03). Vitamin A significantly reduced low birth weight in a multivariate analysis controlling for maternal age, body mass index, and CD4+ count...
  10. MICRONUTRIENTS AND MOTHER TO CHILD TRANSMISSION OF HIV
    Richard Semba; Fiscal Year: 2001
    ..03). Vitamin A significantly reduced low birth weight in a multivariate analysis controlling for maternal age, body mass index, and CD4+ count...
  11. MICRONUTRIENTS AND MOTHER TO CHILD TRANSMISSION OF HIV
    Richard Semba; Fiscal Year: 2001
    ..03). Vitamin A significantly reduced low birth weight in a multivariate analysis controlling for maternal age, body mass index, and CD4+ count...
  12. MICRONUTRIENTS AND MOTHER TO CHILD TRANSMISSION OF HIV
    Richard Semba; Fiscal Year: 1999
    ..03). Vitamin A significantly reduced low birth weight in a multivariate analysis controlling for maternal age, body mass index, and CD4+ count...
  13. COOPERATIVE MULTICENTER REPRODUCTIVE MEDICINE NETWORK
    Sandra Carson; Fiscal Year: 1990
    ..Confounding variables (e.g., maternal age, previous losses smoking, alcohol intake) will be recorded, and subjects then randomized to progesterone or ..
  14. COOPERATIVE MULTICENTER REPRODUCTIVE MEDICINE NETWORK
    Sandra Carson; Fiscal Year: 1991
    ..Confounding variables (e.g., maternal age, previous losses smoking, alcohol intake) will be recorded, and subjects then randomized to progesterone or ..
  15. Clinical Measures to Lower Genital Tract Trauma at Birth
    Leah Albers; Fiscal Year: 2004
    ..three strategies on the likelihood of an intact perineum after birth, with control for confounding variables (maternal age and parity, birth position, style of pushing, size and position of baby at birth, length of second stage, and ..
  16. Clinical Measures to Lower Genital Tract Trauma at Birth
    Leah Albers; Fiscal Year: 2003
    ..three strategies on the likelihood of an intact perineum after birth, with control for confounding variables (maternal age and parity, birth position, style of pushing, size and position of baby at birth, length of second stage, and ..
  17. Clinical Measures to Lower Genital Tract Trauma at Birth
    Leah Albers; Fiscal Year: 2001
    ..three strategies on the likelihood of an intact perineum after birth, with control for confounding variables (maternal age and parity, birth position, style of pushing, size and position of baby at birth, length of second stage, and ..
  18. Clinical Measures to Lower Genital Tract Trauma at Birth
    Leah Albers; Fiscal Year: 2002
    ..three strategies on the likelihood of an intact perineum after birth, with control for confounding variables (maternal age and parity, birth position, style of pushing, size and position of baby at birth, length of second stage, and ..
  19. Maternal Morbidity and Mortality in Multiple Pregnancy
    Barbara Luke; Fiscal Year: 2006
    ..are limited, though, by their small sample sizes and frequent failure to control for the confounding factors of maternal age and parity...
  20. Maternal Morbidity and Mortality in Multiple Pregnancy
    Barbara Luke; Fiscal Year: 2005
    ..are limited, though, by their small sample sizes and frequent failure to control for the confounding factors of maternal age and parity...
  21. PRENATAL DOWN SYNDROME SCREENING
    Rachel Fisher; Fiscal Year: 1991
    ..The risk of delivering a baby with Down syndrome (DS) increases with increasing maternal age [2]. By offering amniocentesis to women 35 and over, approximately 20% of DS pregnancies can be detected...
  22. Plurality and Contemporary Infant Mortality Risks
    Barbara Luke; Fiscal Year: 2006
    ..Older maternal age requires more aggressive therapies to achieve a pregnancy, including transferring more embryos...
  23. COMPARISON OF CHORION VILLUS SAMPLING AND AMNIOCENTESIS
    ROBERT DESNICK; Fiscal Year: 1990
    ..induced abortion material or specimens obtained from newborns monitored for indications other than advanced maternal age. Clinical evaluations will be performed on all monitored infants in the newborn nursery and at 6 months of age...
  24. Epidemiology of Abruptio Placentae in Peru
    Michelle Williams; Fiscal Year: 2007
    ..Risk factors to be considered include young and advanced maternal age, grand multiparity (parity > 5), maternal smoking, prior history of stillbirth, c-section delivery and other ..
  25. NOVEL EVALUATION OF LACTATION PERFORMANCE
    Cutberto Garza; Fiscal Year: 1990
    ..the contexts of these assessments associations have been sought most commonly between lactation performance and maternal age, maternal nutritional status, length of pregnancy, duration of lactation, lactation management protocols, and ..
  26. Epidemiology of Abruptio Placentae in Peru
    Michelle Williams; Fiscal Year: 2006
    ..Risk factors to be considered include young and advanced maternal age, grand multiparity (parity > 5), maternal smoking, prior history of stillbirth, c-section delivery and other ..
  27. Spontaneous Arousals in "CHIME" Infants at Risk for SIDS
    ROBERT DARNALL; Fiscal Year: 2004
    ..In addition, important demographic data were collected including maternal age, cigarette smoking, and alcohol use...
  28. Spontaneous Arousals in "CHIME" Infants at Risk for SIDS
    ROBERT DARNALL; Fiscal Year: 2005
    ..In addition, important demographic data were collected including maternal age, cigarette smoking, and alcohol use...
  29. Spontaneous Arousals in "CHIME" Infants at Risk for SIDS
    ROBERT DARNALL; Fiscal Year: 2006
    ..In addition, important demographic data were collected including maternal age, cigarette smoking, and alcohol use...
  30. Quasi-experimental studies of early risk factors for severe psychopathology
    Paul Lichtenstein; Fiscal Year: 2010
    ..risk for these severe problems, including maternal smoking during pregnancy, maternal stress during pregnancy, maternal age at childbearing, and advancing paternal age at childbearing...
  31. THE BIODEMOGRAPHY OF HUMAN LONGEVITY--A TRAINING PROGRAM
    Leonid Gavrilov; Fiscal Year: 2004
    ..importance of mutation load on the paternal X chromosome inherited by daughters only); (2) to analyze the maternal age effects on offspring longevity (in relation to the possible role of age-related accumulation of oxidative ..
  32. THE BIODEMOGRAPHY OF HUMAN LONGEVITY--A TRAINING PROGRAM
    Leonid Gavrilov; Fiscal Year: 2003
    ..importance of mutation load on the paternal X chromosome inherited by daughters only); (2) to analyze the maternal age effects on offspring longevity (in relation to the possible role of age-related accumulation of oxidative ..
  33. THE BIODEMOGRAPHY OF HUMAN LONGEVITY--A TRAINING PROGRAM
    Leonid Gavrilov; Fiscal Year: 2002
    ..importance of mutation load on the paternal X chromosome inherited by daughters only); (2) to analyze the maternal age effects on offspring longevity (in relation to the possible role of age-related accumulation of oxidative ..
  34. THE BIODEMOGRAPHY OF HUMAN LONGEVITY--A TRAINING PROGRAM
    Leonid Gavrilov; Fiscal Year: 2001
    ..importance of mutation load on the paternal X chromosome inherited by daughters only); (2) to analyze the maternal age effects on offspring longevity (in relation to the possible role of age-related accumulation of oxidative ..
  35. THE BIODEMOGRAPHY OF HUMAN LONGEVITY--A TRAINING PROGRAM
    Leonid Gavrilov; Fiscal Year: 2005
    ..importance of mutation load on the paternal X chromosome inherited by daughters only); (2) to analyze the maternal age effects on offspring longevity (in relation to the possible role of age-related accumulation of oxidative ..
  36. Plurality and Contemporary Infant Mortality Risks
    Barbara Luke; Fiscal Year: 2005
    ..Older maternal age requires more aggressive therapies to achieve a pregnancy, including transferring more embryos...
  37. CHROMOSOME PAIRING AND NONDISJUNCTION IN HUMAN MEIOSIS
    Edith Cheng; Fiscal Year: 1999
    ..that have been proposed to explain the high incidence of aneuploidy in female gametes and the related maternal age effect...
  38. ULTRASOUND SCREENING AND RISK ASSESSMENT OF PREGNANCY
    Fredric Frigoletto; Fiscal Year: 1993
    ..Eligibility for the study as well as risk factors for pregnancy outcome such as maternal age, socioeconomic status, prior obstetrical history, prepregnancy weight and nutrition, active and passive smoking,..
  39. CHROMOSOME PAIRING AND NONDISJUNCTION IN HUMAN MEIOSIS
    Edith Cheng; Fiscal Year: 2000
    ..that have been proposed to explain the high incidence of aneuploidy in female gametes and the related maternal age effect...
  40. Advanced Reproductive Technology and Infant Health
    Marianne Bitler; Fiscal Year: 2005
    ..impacts of ART use and of state-mandated insurance coverage of infertility treatment on the number of births, maternal age at birth, and the incidence of multiple births, using both the NSFG and Vital Statistics birth certificate data;..
  41. Advanced Reproductive Technology and Infant Health
    Marianne Bitler; Fiscal Year: 2004
    ..impacts of ART use and of state-mandated insurance coverage of infertility treatment on the number of births, maternal age at birth, and the incidence of multiple births, using both the NSFG and Vital Statistics birth certificate data;..
  42. CONTROL OF MEIOSIS AND GERMLINE PROLIFERATION
    David Greenstein; Fiscal Year: 2009
    ..elegans will define the signaling mechanisms controlling late events in oogenesis and provide insights into how they may go awry when signaling is perturbed. ..
  43. CONTROL OF MEIOSIS AND GERMLINE PROLIFERATION
    DAVID I GREENSTEIN; Fiscal Year: 2010
    ..elegans will define the signaling mechanisms controlling late events in oogenesis and provide insights into how they may go awry when signaling is perturbed. ..
  44. OMEGA-3 AND OMEGA-6 FATTY ACIDS AND PREMATURE INFANTS
    Susan Carlson; Fiscal Year: 1993
    ..neonatal/perinatal variables such as birth wt, gestational age, age at enrollment, O2, ventilatory support, maternal age and gravida...
  45. Impact of Intrauterine Tobacco Smoke Exposure on Umbilical Cord Blood Stem Cells
    JENNIFER KORNOSKY; Fiscal Year: 2009
    ..Regression models that control for potential confounders such as serum folate, maternal age, parity, race/ethnicity, body mass index status, previous IUGR/fetal death, and fetal gender will be developed ..
  46. IN SITU HYBRIDIZATION IN PRENATAL DIAGNOSIS
    Kenneth Castleman; Fiscal Year: 1993
    ..of these five chromosomes occur in approximately 2% of all prenatal diagnostic tests done for "advanced maternal age", and account for the great majority of all viable cytogenetic abnormalities observed at amniocentesis or CVS...
  47. The Epidemiology of Hospitalized Postpartum Depression
    David Savitz; Fiscal Year: 2009
    ..cases and appears to disproportionately afflict socioeconomically disadvantaged women at the extremes of the maternal age distribution...
  48. Age and molecular mechanisms contributing to aneuploidy in oocytes
    Richard Schultz; Fiscal Year: 2009
    ..Most aneuplodies associated with increased maternal age are due to non-disjunction and meiotic errors that occur during meiosis...
  49. HOMOCYST (E) INE, VITAMINS & GENETIC INTERACTIONS IN VASCULAR DISEASE
    M Malinow; Fiscal Year: 2000
    ..5 umol/L (upper decile of distribution of control values). Adjusted for maternal age, parity, and body mass-index, a second trimester elevation of homocyst(e)ine was associated with a 3...
  50. Ectopic Pregnancy: Assessing Long-Term Trends in Rates and Risk Factors
    Delia Scholes; Fiscal Year: 2007
    ..EP rates may not be declining; and a number of important risk factors-including tubal sterilization, advanced maternal age and Chlamydia trachomatis and other asymptomatic sexually transmitted infections -have become increasingly ..
  51. Mediating Factors in the Relationship between Obesity and Poor Lactation Outcomes
    LAURIE ANN NOMMSEN RIVERS; Fiscal Year: 2010
    ..n=405 breastfeeding women with complete data;32% obese) were greater maternal body mass index, older maternal age, greater infant birth weight, and use of infant formula...
  52. GENERAL CLINICAL RESEARCH CENTER
    THOMAS BOAT; Fiscal Year: 1999
    ..2. Bone Health. Studies will examine the effect of maternal age during lactation on bone demineralization and the value of progestins in ameliorating the loss...
  53. Advanced Reproductive Age and Environmental Health
    Stephanie Engel; Fiscal Year: 2006
    ..We propose to enroll 200 women of advanced maternal age (AMA) in a prospective pregnancy cohort, and to assemble a repository of maternal biological specimens ..
  54. DIET, IMMUNE MODULATION, AND ASTHMA IN EARLY LIFE
    Scott Weiss; Fiscal Year: 2002
    ..potentially influential host and environmental factors to be examined include: parental asthma history, maternal age, perinatal history, acute lower respiratory illness history, day care, environmental tobacco smoke, birthweight,..
  55. DIET, IMMUNE MODULATION, AND ASTHMA IN EARLY LIFE
    Scott Weiss; Fiscal Year: 2000
    ..potentially influential host and environmental factors to be examined include: parental asthma history, maternal age, perinatal history, acute lower respiratory illness history, day care, environmental tobacco smoke, birthweight,..
  56. DIET, IMMUNE MODULATION, AND ASTHMA IN EARLY LIFE
    Scott Weiss; Fiscal Year: 2001
    ..potentially influential host and environmental factors to be examined include: parental asthma history, maternal age, perinatal history, acute lower respiratory illness history, day care, environmental tobacco smoke, birthweight,..
  57. GENERAL CLINICAL RESEARCH CENTER
    THOMAS BOAT; Fiscal Year: 2000
    ..2. Bone Health. Studies will examine the effect of maternal age during lactation on bone demineralization and the value of progestins in ameliorating the loss...
  58. DIET, IMMUNE MODULATION, AND ASTHMA IN EARLY LIFE
    Scott Weiss; Fiscal Year: 1999
    ..potentially influential host and environmental factors to be examined include: parental asthma history, maternal age, perinatal history, acute lower respiratory illness history, day care, environmental tobacco smoke, birthweight,..
  59. GENERAL CLINICAL RESEARCH CENTER
    THOMAS BOAT; Fiscal Year: 2001
    ..2. Bone Health. Studies will examine the effect of maternal age during lactation on bone demineralization and the value of progestins in ameliorating the loss...
  60. GENERAL CLINICAL RESEARCH CENTER
    THOMAS BOAT; Fiscal Year: 1999
    ..2. Bone Health. Studies will examine the effect of maternal age during lactation on bone demineralization and the value of progestins in ameliorating the loss...
  61. Advanced Reproductive Age and Environmental Health
    Stephanie Engel; Fiscal Year: 2007
    ..We propose to enroll 200 women of advanced maternal age (AMA) in a prospective pregnancy cohort, and to assemble a repository of maternal biological specimens ..
  62. Segregation of error-prone chromosomes in meiosis
    Dean Dawson; Fiscal Year: 2007
    ..The incidence of conceptuses with inappropriate numbers of chromosomes rises with increased maternal age. Recombination between homologous chromosomes greatly increases the probability that they will segregate ..
  63. ROLE OF DIETARY N-3 FATTY ACIDS IN PREMATURE INFANTS
    Susan Carlson; Fiscal Year: 1990
    ..neonatal/perinatal variables such as birth wt, gestational age, age at enrollment, O2, ventilatory support, maternal age and gravida...
  64. Segregation of error-prone chromosomes in meiosis
    Dean S Dawson; Fiscal Year: 2010
    ..The incidence of conceptuses with inappropriate numbers of chromosomes rises with increased maternal age. Recombination between homologous chromosomes greatly increases the probability that they will segregate ..