Genomes and Genes
Summary: The age of the mother in PREGNANCY.
Publications350 found, 100 shown here
- Advanced maternal age. Part I: obstetric complicationsIhab M Usta
Department of Obstetrics and Gynecology, American University of Beirut Medical Center, Beirut, Lebanon
Am J Perinatol 25:521-34. 2008More women are postponing pregnancy into the fourth and fifth decades of life for a variety of reasons. Advanced maternal age, traditionally defined as age more than 35 years, has been associated with increased obstetric morbidity and ..
- Advanced maternal age and the risk of cesarean birth: a systematic reviewHamideh Bayrampour
Faculty of Nursing, University of Manitoba, Winnipeg, Manitoba, Canada
Birth 37:219-26. 2010The increasing pregnancy rate at advanced maternal age is contemporaneous with the increasing rate of cesarean birth. Several studies have found that advanced maternal age is a risk factor for cesarean birth...
- Advanced maternal age and adverse perinatal outcomeBo Jacobsson
Perinatal Centre, Department of Obstetrics and Gynecology, Sahlgrenska University Hospital Ostra, S 416 85 Goteborg, Sweden
Obstet Gynecol 104:727-33. 2004The aim of this study was to investigate the influence of maternal age on perinatal and obstetric outcome in women aged 40-44 years and those 45 years or older and to estimate whether adverse outcome was related to intercurrent illness ..
- Demographic and medical consequences of the postponement of parenthoodL Schmidt
Section of Social Medicine, Department of Public Health, University of Copenhagen, Denmark
Hum Reprod Update 18:29-43. 2012..Increasing public awareness of the impact of advanced female and male age on the reproductive outcome is essential for people to make well-informed decisions on when to start family formation...
- Advancing paternal age and risk of autism: new evidence from a population-based study and a meta-analysis of epidemiological studiesC M Hultman
Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
Mol Psychiatry 16:1203-12. 2011..26-3.88: P=0.006) more likely to have autism than offspring of men aged ≤29 years, after controlling for maternal age and documented risk factors for autism...
- Maternal age and fetal loss: population based register linkage studyA M Nybo Andersen
Department of Epidemiology Research, Danish Epidemiology Science Centre, Statens Serum Institut, DK 2300 Copenhagen S, Denmark
BMJ 320:1708-12. 2000To estimate the association between maternal age and fetal death (spontaneous abortion, ectopic pregnancy, stillbirth), taking into account a woman's reproductive history.
- The perinatal effects of delayed childbearingK S Joseph
Perinatal Epidemiology Research Unit, Departments of Obstetrics and Gynaecology and Pediatrics, Dalhousie University, Halifax, Nova Scotia, Canada
Obstet Gynecol 105:1410-8. 2005....
- Caesarean section is associated with an increased risk of childhood-onset type 1 diabetes mellitus: a meta-analysis of observational studiesC R Cardwell
Department of Epidemiology and Public Health, School of Medicine and Dentistry, Queen s University Belfast, Grosvenor Road, Belfast, BT12 6BJ, UK
Diabetologia 51:726-35. 2008....
- Advanced maternal age and adverse perinatal outcome: a review of the evidenceMary Carolan
Department of Nursing and Midwifery, University of Limerick, Ireland
Midwifery 27:793-801. 2011To examine the evidence in relation to advanced maternal age (35-39 years), physiological risk and adverse perinatal outcome (stillbirth, low birth weight, preterm birth) in high-income countries.
- Prevalence of smoking during pregnancy and associated risk factors among Canadian women: a national surveyBan Al-Sahab
School of Kinesiology and Health Science, York University, Toronto, ON Canada M3J 1P3
BMC Pregnancy Childbirth 10:24. 2010..Therefore, the study aims to assess the prevalence of smoking during pregnancy and its associated risk factors throughout the Canadian provinces and territories...
- Assisted reproductive technologies (ART) in Canada: 2007 results from the Canadian ART RegisterJoanne Gunby
Pegasus Technologies, Burlington, Ontario, Canada
Fertil Steril 95:542-7.e1-10. 2011..To present a report on assisted reproductive technologies (ART) cycles performed in 2007 in Canada and show trends in outcomes over time. This is the seventh annual report from the Canadian ART Register (CARTR)...
- The maternal age-specific live birth prevalence of trisomies 13 and 18 compared to trisomy 21 (Down syndrome)George M Savva
Department of Public Health and Primary Care, University of Cambridge, Institute of Public Health, Cambridge, UK
Prenat Diagn 30:57-64. 2010To estimate the maternal age-specific live birth prevalence (in the absence of prenatal diagnosis and selective termination) of trisomy 13 (Patau syndrome) and trisomy 18 (Edwards syndrome) and compare it with that of trisomy 21 (Down ..
- Pregnancy outcome at extremely advanced maternal ageYariv Yogev
Department of Obstetrics and Gynecology, Perinatal Division, Helen Schneider Hospital for Women, Rabin Medical Center, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
Am J Obstet Gynecol 203:558.e1-7. 2010The purpose of this study was to evaluate pregnancy outcome in women at extremely advanced maternal age (≥ 45 years).
- Comprehensive embryo analysis of advanced maternal age-related aneuploidies and mosaicism by short comparative genomic hybridizationMariona Rius
Unitat de Biologia Cellular i Genetica Medica, Facultat de Medicina, Universitat Autonoma de Barcelona, Bellaterra, Spain
Fertil Steril 95:413-6. 2011..short-CGH) method was used to perform a comprehensive cytogenetic study of isolated blastomeres from advanced maternal age embryos, discarded after fluorescent in situ hybridization (FISH) preimplantation genetic screening (PGS), ..
- Transcriptomic profiling of human oocytes: association of meiotic aneuploidy and altered oocyte gene expressionE Fragouli
Nuffield Department of Obstetrics and Gynaecology, University of Oxford, Oxford, UK
Mol Hum Reprod 16:570-82. 2010..Aneuploidy is also closely related with advancing maternal age, a phenomenon not well understood...
- Cumulative incidence of type 1 diabetes in 10,168 siblings of Finnish young-onset type 1 diabetic patientsValma Harjutsalo
Diabetes and Genetic Epidemiology Unit, Department of Epidemiology and Health Promotion, National Public Health Institute, Mannerheimintie 166, FIN 00300, Helsinki, Finland
Diabetes 54:563-9. 2005..This large prospective family study of type 1 diabetes in siblings of childhood-onset diabetic patients provides reliable empirical estimates for the sibling recurrence risk...
- Multiple meiotic errors caused by predivision of chromatids in women of advanced maternal age undergoing in vitro fertilisationAlan H Handyside
London Bridge Fertility, Gynaecology and Genetics Centre, London, UK
Eur J Hum Genet 20:742-7. 2012..live births following both natural conception and in vitro fertilisation (IVF) and increases exponentially with maternal age in the decade preceding the menopause...
- Advancing maternal age is associated with increasing risk for autism: a review and meta-analysisSven Sandin
Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, PO Box 281, SE 171 77 Stockholm, Sweden
J Am Acad Child Adolesc Psychiatry 51:477-486.e1. 2012We conducted a meta-analysis of epidemiological studies investigating the association between maternal age and autism.
- Polar body array CGH for prediction of the status of the corresponding oocyte. Part I: clinical resultsJoep Geraedts
Department of Genetics and Cell Biology, Research Institute GROW, Faculty of Health, Medicine and Life Sciences, Maastricht University, PO Box 5800, Maastricht, AZ 6202, The Netherlands
Hum Reprod 26:3173-80. 2011..e. PGS by polar body (PB) biopsy, with whole genome amplification and microarray-based comparative genomic hybridization (array CGH) analysis...
- Perinatal factors and the development of autism: a population studyEmma J Glasson
Schools of Population Health and Psychiatry and Clinical Neurosciences, University of Western Australia, Crawley, Australia
Arch Gen Psychiatry 61:618-27. 2004..Some investigations have shown an association with obstetric complications but findings have been inconsistent owing to differences in sampling and methods...
- Late age at first full term birth is strongly associated with lobular breast cancerPolly A Newcomb
University of Wisconsin Carbone Comprehensive Cancer Center, Madison, Wisconsin, USA
Cancer 117:1946-56. 2011..Late age at first full-term birth and nulliparity are known to increase breast cancer risk. The frequency of these risk factors has increased in recent decades...
- Epidemiology of congenital anomalies in a population-based birth registry in Taiwan, 2002Bing Yu Chen
Institute of Occupational Medicine and Industrial Hygiene, College of Public Health, National Taiwan University, Taipei 100, Taiwan
J Formos Med Assoc 108:460-8. 2009..We used the medical-practitioner-reported birth registry in 2002 to determine the occurrence of individual congenital anomalies and their associated risk factors, such as maternal age, fetal sex, and plurality.
- Maternal smoking in pregnancy, fetal development, and childhood asthmaJouni J K Jaakkola
Institute of Occupational Health, The University of Birmingham, Birmingham, United Kingdom
Am J Public Health 94:136-40. 2004..We examined the relationships among maternal smoking in pregnancy, fetal development, and the risk of asthma in childhood...
- Maternal characteristics and lifestyle factors and the risk of delivering high birth weight infantsJanne Ørskou
Perinatal Epidemiological Research Unit, Department of Obstetrics and Gynaecology, Aarhus University Hospital, Aarhus, Denmark
Obstet Gynecol 102:115-20. 2003....
- Advancing paternal age and autismAbraham Reichenberg
Department of Psychiatry and Seaver Center for Autism Research, Mount Sinai School of Medicine, One Gustave L Levy Place, New York, NY 10029, USA
Arch Gen Psychiatry 63:1026-32. 2006..Maternal and paternal ages are associated with neurodevelopmental disorders...
- Advanced maternal age and risk of antepartum and intrapartum stillbirthHamisu M Salihu
Department of Epidemiology and Biostatistics, University of South Florida, Tampa, Florida, USA
J Obstet Gynaecol Res 34:843-50. 2008..We sought to assess the risk of antepartum and intrapartum stillbirth subtypes among women of advanced age...
- Paternal age at birth and high-functioning autistic-spectrum disorder in offspringKenji J Tsuchiya
Osaka Hamamatsu Joint Research Center for Child Mental Development OHJRC CMD, Hamamatsu University School of Medicine, Hamamatsu 431 3192, Japan
Br J Psychiatry 193:316-21. 2008..Previous studies have reported the association between advanced paternal age at birth and the risk of autistic-spectrum disorder in offspring, including offspring with intellectual disability...
- Consanguinity and advanced maternal age as risk factors for reproductive losses in Alexandria, EgyptM M Mokhtar
Department of Huiman Genetics, Medical Research Institute, Alexandria University, Egypt
Eur J Epidemiol 17:559-65. 2001..This study aimed at delineating the role of consanguinity and advanced maternal age on reproductive losses in Alexandria, Egypt...
- Associations of parental, birth, and early life characteristics with systolic blood pressure at 5 years of age: findings from the Mater-University study of pregnancy and its outcomesDebbie A Lawlor
Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Rd, Bristol, BS8 2PR, UK
Circulation 110:2417-23. 2004..We examined the associations of a range of parental and early life characteristics with systolic blood pressure at 5 years of age...
- The effect of maternal anthropometric characteristics and social factors on gestational age and birth weight in Sudanese newborn infantsEltahir M Elshibly
Clinic of Neonatology Campus Charité Mitte, Universitatsmedizin Berlin, Germany
BMC Public Health 8:244. 2008..The aim of this study was to quantify the effect of maternal anthropometry, education and socio-economic status on gestational age and birth weight...
- Comparison of models of maternal age-specific risk for Down syndrome live birthsJ K Morris
Department of Environmental and Preventive Medicine, Wolfson Institute of Preventive Medicine, St Bartholomew s and the Royal London School of Medicine and Dentistry, Charterhouse Square, London EC1M 6BQ, UK
Prenat Diagn 23:252-8. 2003To display and compare the different published formulae that specify the association between maternal age and the risk of a Down syndrome live birth.
- Trends in mode of delivery during 1984-2003: can they be explained by pregnancy and delivery complications?C M O'Leary
Telethon Institute for Child Health Research, Centre for Child Health Research, The University of Western Australia, West Perth, Western Australia, Australia
BJOG 114:855-64. 2007..To describe trends in mode of delivery, to identify significant factors which affected mode of delivery, and to describe how these factors and their impact have changed over time...
- SNP microarray-based 24 chromosome aneuploidy screening demonstrates that cleavage-stage FISH poorly predicts aneuploidy in embryos that develop to morphologically normal blastocystsL E Northrop
Reproductive Medicine Associates of New Jersey, Morristown, NJ 07960, USA
Mol Hum Reprod 16:590-600. 2010..These findings support the conclusion that cleavage-stage FISH technology is poorly predictive of aneuploidy in morphologically normal blastocysts...
- Impact of maternal age on obstetric outcomeJane Cleary-Goldman
Columbia University Medical Center, New York, New York, USA
Obstet Gynecol 105:983-90. 2005To estimate the effect of maternal age on obstetric outcomes.
- Maternal age and malformations in singleton birthsL M Hollier
Department of Obstetrics and Gynecology, University of Texas Southwestern Medical Center, Dallas, Texas, USA
Obstet Gynecol 96:701-6. 2000To examine the effect of maternal age on incidence of nonchromosomal fetal malformations.
- Pregnancy outcome at age 40 and olderS Ziadeh
Arch Gynecol Obstet 265:30-3. 2001..Our purpose was to examine pregnancy outcomes among women age 40 or older...
- Optimal fetal growth for the Caucasian singleton and assessment of appropriateness of fetal growth: an analysis of a total population perinatal databaseEve M Blair
Centre for Child Health Research, The University of Western Australia, at the Telethon Institute for Child Health Research, P, O, Box 855, West Perth, WA, 6872, Australia
BMC Pediatr 5:13. 2005..Appropriateness of growth can then be inferred from the ratio of the value of the observed dimension to that of the optimal dimension...
- Elective induction of labor as a risk factor for cesarean delivery among low-risk women at termA S Maslow
Department of Clinical Outcomes and Quality Improvement, Franciscan Health System, Tacoma, Washington, USA
Obstet Gynecol 95:917-22. 2000..To determine the effects of elective induction on the risk of cesarean delivery in a cohort of women with low-risk term pregnancies and to evaluate the costs of elective induction services within our hospital system...
- Factors influencing childbearing decisions and knowledge of perinatal risks among Canadian men and womenSuzanne Tough
Faculty of Medicine, University of Calgary, Room C4 301, 2888 Shaganappi Trail NW, Calgary, AB, T3B 6A8, Canada
Matern Child Health J 11:189-98. 2007..Little is known about men's and women's understanding of the maternal age related risks to pregnancy.
- Modifiable maternal exposures and offspring blood pressure: a review of epidemiological studies of maternal age, diet, and smokingMarie Jo A Brion
Department of Social Medicine, University of Bristol, Bristol BS8 2PR, United Kingdom
Pediatr Res 63:593-8. 2008..The results of studies of maternal age varied and there was strong evidence of heterogeneity in the pooled analysis...
- Recombination rate and reproductive success in humansAugustine Kong
deCODE Genetics, Sturlugata 8, IS 101 Reykjavik, Iceland
Nat Genet 36:1203-6. 2004..meioses each, and found a positive correlation between maternal recombination counts of an offspring and maternal age. We postulated that the recombination rate of eggs does not increase with maternal age, but that the apparent ..
- To err (meiotically) is human: the genesis of human aneuploidyT Hassold
Department of Genetics, Case Western Reserve University, 10, 900 Euclid Avenue, Cleveland, Ohio 44106, USA
Nat Rev Genet 2:280-91. 2001..However, recent molecular and cytogenetic approaches are now beginning to shed light on the non-disjunctional processes that lead to aneuploidy...
- Paternal age and intelligence: implications for age-related genomic changes in male germ cellsDolores Malaspina
New York State Psychiatric Institute and Columbia University, New York, NY 10032, USA
Psychiatr Genet 15:117-25. 2005..There are also substantial genetic influences on intelligence, so de novo genetic events in male germ cells, which accompany advancing paternal age, may plausibly influence offspring intelligence...
- Comparison of obstetric outcomes in recipients of donor oocytes vs. women of advanced maternal age with autologous oocytesMelinda B Henne
Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, Stanford University School of Medicine, Stanford, California, USA
J Reprod Med 52:585-90. 2007To evaluate obstetric complications in women conceiving with donated oocytes as compared to controls of advanced maternal age.
- Advanced maternal age: are decisions about the timing of child-bearing a failure to understand the risks?Karen M Benzies
Faculty of Nursing, University of Calgary, Calgary, Alta
CMAJ 178:183-4. 2008
- Age at first birth, mode of conception and psychological wellbeing in pregnancy: findings from the parental age and transition to parenthood Australia (PATPA) studyC A McMahon
Centre for Emotional Health, Department of Psychology, Macquarie University, Sydney, NSW 2109, Australia
Hum Reprod 26:1389-98. 2011..We aimed to describe the context of pregnancy for first-time mothers of different ages and examine relationships among maternal age at first birth, mode of conception and psychosocial wellbeing in pregnancy.
- A cost-effectiveness analysis of in-vitro fertilization by maternal age and number of treatment attemptsAlison Griffiths
NHMRC Clinical Trials Centre, The University of Sydney, Camperdown, NSW 2050, Australia
Hum Reprod 25:924-31. 2010..A decision analytic model was designed to estimate the incremental cost-effectiveness of IVF by additional treatment programmes and maternal age.
- Paternal age at birth of first child and risk of schizophreniaLiselotte Petersen
National Centre for Register Based Research, Aarhus University, Denmark
Am J Psychiatry 168:82-8. 2011..The authors aimed to distinguish between these two measures of paternal age...
- Age-dependent recombination rates in human pedigreesJulie Hussin
Department of Biochemistry, Faculty of Medicine, University of Montreal, Montreal, Canada
PLoS Genet 7:e1002251. 2011In humans, chromosome-number abnormalities have been associated with altered recombination and increased maternal age. Therefore, age-related effects on recombination are of major importance, especially in relation to the mechanisms ..
- Autism and intellectual disability are differentially related to sociodemographic background at birthHelen Leonard
Telethon Institute for Child Health Research, Centre for Child Health Research, The University of Western Australia, West Perth, Western Australia, Australia
PLoS ONE 6:e17875. 2011..Research findings investigating the sociodemographics of autism spectrum disorder (ASD) have been inconsistent and rarely considered the presence of intellectual disability (ID)...
- Development of heart block in children of SSA/SSB-autoantibody-positive women is associated with maternal age and displays a season-of-birth patternAurelie Ambrosi
Department of Medicine, Karolinska Institutet, Stockholm, Sweden
Ann Rheum Dis 71:334-40. 2012..The authors investigated the influence of other maternal and fetal factors on heart block development in a Swedish population-based cohort...
- Trends and geographic inequalities in the prevalence of Down syndrome in Europe, 1980-1999H Dolk
EUROCAT Central Registry, Room 15E12, Faculty of Life and Health Sciences, University of Ulster at Jordanstown, Shore Rd, Newtownabbey BT37 OQB, Ulster, UK
Rev Epidemiol Sante Publique 53:2S87-95. 2005..In this paper, we aim to examine trends in the live birth prevalence of Down syndrome in Europe in the light of trends in maternal age and in prenatal diagnosis.
- Advanced maternal age--how old is too old?Linda J Heffner
Department of Obstetrics and Gynecology, Boston University School of Medicine, Boston, USA
N Engl J Med 351:1927-9. 2004
- Temporal changes in key maternal and fetal factors affecting birth outcomes: a 32-year population-based study in an industrial citySvetlana V Glinianaia
Institute of Health and Society, Newcastle University, William Leech Building, The Medical School, Framlington Place, Newcastle upon Tyne, NE2 4HH, UK
BMC Pregnancy Childbirth 8:39. 2008..The objective of this study was to describe temporal changes in key maternal and fetal factors affecting birth outcomes in Newcastle upon Tyne over three decades, 1961-1992...
- Maternal age and chromosomally abnormal pregnancies: what we know and what we wish we knewTerry Hassold
School of Molecular Biosciences and Center for Reproductive Biology, Washington State University, Pullman, Washington 99164, USA
Curr Opin Pediatr 21:703-8. 2009The relationship between increasing maternal age and trisomy has been recognized for over 50 years and is one of the most important etiological factors associated with any human genetic disorder...
- Gestational age, birth weight, and risk for injuries in childhoodYuelian Sun
Department of Epidemiology, Institute of Public Health, University of Aarhus, Aarhus, Denmark
Epidemiology 21:650-7. 2010..Most injury studies have focused on proximal causes; few have examined the role of neonatal characteristics such as birth weight and gestational age...
- Pregnancy outcomes for nulliparous women of advanced maternal age in South Australia, 1998-2008Isobel Ludford
Office of Public Health, Department for Health and Ageing, 11 Hindmarsh Square, Adelaide, SA 5000, Australia
Aust N Z J Obstet Gynaecol 52:235-41. 2012..Child bearing in the later reproductive years has become increasingly common in Australia with potential implications for clinical practice...
- Assisted reproductive technologies in Canada: 2005 results from the Canadian Assisted Reproductive Technologies RegisterJoanne Gunby
Pegasus Technologies, Burlington, Ontario, Canada
Fertil Steril 91:1721-30. 2009..To present a report on assisted reproductive technologies (ART) cycles performed in 2005 in Canada. This is the fifth annual report from the Canadian ART Register (CARTR)...
- Parental ages and levels of DNA methylation in the newborn are correlatedRonald M Adkins
Department of Pediatrics, University of Tennessee Health Science Center, Memphis, TN 38103, USA
BMC Med Genet 12:47. 2011..Only a proportion of these increased risks among the children of older parents can be attributed to nondisjunction and chromosomal rearrangements...
- A significant linear association exists between advanced maternal age and adverse perinatal outcomeShimrit Salem Yaniv
Department of Obstetrics and Gynecology, Soroka University Medical Center, P O Box 151, Beersheba, Israel
Arch Gynecol Obstet 283:755-9. 2011..The present study was aimed to investigate perinatal outcome of elderly nulliparous patients...
- Maternal age effect on the development of Prader-Willi syndrome resulting from upd(15)mat through meiosis 1 errorsKeiko Matsubara
Department of Molecular Endocrinology, National Research Institute for Child Health and Development, 2 10 1 Ohkura, Setagaya, Tokyo, Japan
J Hum Genet 56:566-71. 2011..Of these factors involved in the development of upd(15)mat, M1 non-disjunction is a maternal age-dependent phenomenon...
- Effect of maternal age on mitochondrial DNA copy number, ATP content and IVF outcome of bovine oocytesHisataka Iwata
Tokyo University of Agriculture, Funako 1737, Atugi City 243 0034, Japan
Reprod Fertil Dev 23:424-32. 2011The primary aim of the present study was to examine the effect of maternal age (in months) on mitochondrial DNA copy number (Mt number), ATP content and IVF outcome of bovine oocytes...
- Obstetric outcomes in donor oocyte pregnancies compared with advanced maternal age in in vitro fertilization pregnanciesSacha A Krieg
Department of Obstetrics and Gynecology, Stanford University School of Medicine, Stanford, California, USA
Fertil Steril 90:65-70. 2008..To evaluate obstetric complications in women who conceived through donated oocytes compared with women who conceived through assisted reproduction using autologous oocytes...
- Defective deacetylation of histone 4 K12 in human oocytes is associated with advanced maternal age and chromosome misalignmentI M van den Berg
Department of Obstetrics and Gynaecology, Subdivision of Reproductive Medicine, Erasmus Medical Centre, Rotterdam, The Netherlands
Hum Reprod 26:1181-90. 2011..meiosis are associated with low fertility in humans and the incidence of these errors increases with advancing maternal age. Studies of mitosis and meiosis suggest that defective remodeling of chromatin plays a causative role in ..
- Can assisted reproduction technology compensate for the natural decline in fertility with age? A model assessmentHenri Leridon
U569 Epidemiology, demography and social sciences IFR69, INSERM French Institute of Health and Medical Research and INED National Institute for Demographic Studies
Hum Reprod 19:1548-53. 2004b>Maternal age is an important factor in reproduction. Can assisted reproduction technologies (ART) fully compensate for the decline in fertility with age?
- Twenty-year trends in the prevalence of Down syndrome and other trisomies in Europe: impact of maternal age and prenatal screeningMaria Loane
Institute of Nursing Research, University of Ulster, Jordanstown, UK
Eur J Hum Genet 21:27-33. 2013..differences in total and live birth prevalence of trisomies 21, 18 and 13 with regard to increasing maternal age and prenatal diagnosis in Europe. Twenty-one population-based EUROCAT registries covering 6...
- Fetal deathRobert M Silver
Department of Obstetrics and Gynecology, University of Utah, Salt Lake City, UT 84132, USA
Obstet Gynecol 109:153-67. 2007..Risk factors for fetal death include African American race, advanced maternal age, obesity, smoking, prior fetal death, maternal diseases, and fetal growth impairment...
- Maternal age, multiple birth, and extremely low birth weight infantsBetty R Vohr
Department of Pediatrics, The Warren Alpert Medical School of Brown University, Providence, RI, USA
J Pediatr 154:498-503.e2. 2009..To compare the rates of adverse neurodevelopmental outcome or death at 18 to 22 months among extremely low birth weight (ELBW) infants born to mothers >or=4 0 years to the corresponding rates among infants of younger mothers...
- Racial differences in gene-specific DNA methylation levels are present at birthRonald M Adkins
University of Tennessee Health Science Center, Memphis, TN 48103, USA
Birth Defects Res A Clin Mol Teratol 91:728-36. 2011..The origin of these differences is inadequately understood, and this is a question of specific relevance to childhood and adult cancer...
- Validation of microarray comparative genomic hybridization for comprehensive chromosome analysis of embryosCristina Gutiérrez-Mateo
Reprogenetics, Livingston, New Jersey, USA
Fertil Steril 95:953-8. 2011..To validate and determine the best array-comparative genomic hybridization (aCGH; array-CGH) protocols for preimplantation genetic screening (PGS)...
- Monozygotic twinning associated with assisted reproductive technologies: a reviewK I Aston
Andrology and IVF Laboratories, Department of Surgery, University of Utah School of Medicine, Salt Lake City, Utah 84108, USA
Reproduction 136:377-86. 2008..birth rates have increased markedly in developed countries since the 1970s for two primary reasons: increasing maternal age and the advent and increasing use of fertility treatments...
- Young maternal age and risk of intrapartum stillbirthRonee E Wilson
Department of Epidemiology and Biostatistics, University of South Florida, Tampa, FL, USA
Arch Gynecol Obstet 278:231-6. 2008..To determine the risk of intrapartum stillbirth among teen mothers...
- The effect of delaying childbirth on primary cesarean section ratesGordon C S Smith
Department of Obstetrics and Gynaecology, Cambridge University, The Rosie Hospital, Cambridge, United Kingdom
PLoS Med 5:e144. 2008..The aims of the present study were (1) to characterize the association between maternal age and the outcome of labor, (2) to determine the proportion of the increase in primary cesarean rates that could ..
- Influence of thyroid autoimmunity and maternal age on the risk of miscarriageLino Sieiro Netto
Faculdade de Medicina Serviços de Endocrinologia, HUCFF, UFRJ, Rio de Janeiro, Brazil
Am J Reprod Immunol 52:312-6. 2004..Another point to be considered is the association of high risk of abortion and maternal age. The aim of the present study was to evaluate if the association between TAI and miscarriage could also be ..
- Risk of autism and increasing maternal and paternal age in a large north American populationJudith K Grether
Environmental Health Investigations Branch, California Department of Public Health, Richmond, California 94804, USA
Am J Epidemiol 170:1118-26. 2009..In adjusted models that included age of the other parent and demographic covariates, a 10-year increase in maternal age was associated with a 38% increase in the odds ratio for autism (odds ratio = 1.38, 95% confidence interval: 1...
- Estimated autism risk and older reproductive ageMarissa D King
Institute for Social and Economic Research and Policy, Columbia University, New York, NY 10027, USA
Am J Public Health 99:1673-9. 2009..We sought to estimate the risk for autism associated with maternal and paternal age across successive birth cohorts...
- Maternal age and paternal age are associated with distinct childhood behavioural outcomes in a general population birth cohortSukanta Saha
Queensland Centre for Mental Health Research, The Park Centre for Mental Health, Locked Bag 500, Richlands Q4077, Australia
Schizophr Res 115:130-5. 2009..The aim of the study was to examine the relationship between paternal and maternal ages and selected behavioural measures in children using a large birth cohort...
- Evidence that a defective spindle assembly checkpoint is not the primary cause of maternal age-associated aneuploidy in mouse eggsFrancesca E Duncan
Department of Biology, University of Pennsylvania, Philadelphia, Pennsylvania, USA
Biol Reprod 81:768-76. 2009Advanced maternal age is unequivocally associated with increased aneuploidy in human eggs and infertility, but the molecular basis for this phenomenon is unknown...
- Chromosome mosaicism in cleavage-stage human embryos: evidence of a maternal age effectSantiago Munne
Institute for Reproductive Medicine and Science, Saint Barnabas Medical Centre, Livingston, NJ 07052, USA
Reprod Biomed Online 4:223-32. 2002..While overall mosaicism did not increase with maternal age, the average maternal age of the embryos that had mosaics caused by mitotic non-disjunction was significantly ..
- Is pregnancy over 45 with very high parity related with adverse maternal and fetal outcomes?A Kale
Department of Obstetrics and Gynecology, Dicle University School of Medicine, Diyarbakir, Turkey
Clin Exp Obstet Gynecol 36:120-2. 2009..To examine whether very high parity and age over 45 years are related with adverse maternal and fetal outcomes...
- Trends in the occurrence, determinants, and consequences of multiple birthsBeatrice Blondel
Epidemiological Research Unit on Perinatal and Women s Health, Institut National de la Sante et de la Recherche Medicale INSERM, Villejuif, France
Semin Perinatol 26:239-49. 2002..to one third of the increase in twin or triplet pregnancies are attributable to a contemporaneous increase in maternal age. Furthermore, in countries with high occurrence of multiple births, 30% to 50% of twin pregnancies and at least ..
- Effect of Body Mass Index on pregnancy outcomes in nulliparous women delivering singleton babiesSohinee Bhattacharya
Dugald Baird Centre for Research on Women s Health, Aberdeen Maternity Hospital, Aberdeen, UK
BMC Public Health 7:168. 2007..In a population based cohort study, using routinely collected data, this paper examines the effect of increasing Body Mass Index (BMI) on pregnancy outcomes in nulliparous women delivering singleton babies...
- Maternal and birth characteristics in relation to childhood leukaemiaDanise Podvin
Department of Epidemiology, School of Public Health and Community Medicine, University of Washington, Seattle, 98195, USA
Paediatr Perinat Epidemiol 20:312-22. 2006..b>Maternal age 35+ years (odds ratio [OR] 1.5; 95% confidence interval [CI] 1.1, 2.0), infant birthweight 4,000+ g (OR 1...
- Dystocia increases with advancing maternal ageAnn Treacy
National Maternity Hospital, Dublin, Ireland
Am J Obstet Gynecol 195:760-3. 2006The purpose of this study was to assess the influence of maternal age on obstetric indices of uterine efficiency in spontaneous nulliparous labor managed according to a standardized protocol in order to determine whether increasing ..
- Cesarean birth in the United States: epidemiology, trends, and outcomesMarian F MacDorman
Reproductive Statistics Branch, Division of Vital Statistics, National Center for Health Statistics, Centers for Disease Control and Prevention, 3311 Toledo Road, Room 7318, Hyattsville, MD 20782, USA
Clin Perinatol 35:293-307, v. 2008..Several studies note an increased risk for neonatal and maternal mortality for medically elective cesareans compared with vaginal births...
- Longitudinal reference ranges for estimated fetal weightSynnøve Lian Johnsen
Department of Obstetrics and Gynecology, Haukeland University Hospital, Bergen, Norway
Acta Obstet Gynecol Scand 85:286-97. 2006..The aims of the present study were to establish reference ranges for the growth of estimated fetal weight (EFW) between gestational weeks 20 and 42 and to determine the effect of fetal and maternal factors...
- Does young maternal age increase the risk of adverse obstetric, fetal and neonatal outcomes: a cohort studyClaire M de Vienne
Department of Obstetrics and Gynecology, University Hospital of Caen, France
Eur J Obstet Gynecol Reprod Biol 147:151-6. 2009To determine whether young maternal age is associated with increased risks of adverse obstetric, fetal and perinatal outcomes.
- Maternal age and risk of stillbirth: a systematic reviewLing Huang
Health Surveillance and Epidemiology Division, Centre for Health Promotion, Public Health Agency of Canada, Ottawa, Ont
CMAJ 178:165-72. 2008..Studies regarding the relation between older maternal age and the risk of stillbirth have yielded inconsistent conclusions...
- Early infant feeding and risk of type 1 diabetes mellitus-a nationwide population-based case-control study in pre-school childrenJ Rosenbauer
Institute of Biometrics and Epidemiology, German Diabetes Centre, Leibniz Institute at Heinrich Heine University Düsseldorf, Germany uni duesseldorf de
Diabetes Metab Res Rev 24:211-22. 2008..Reducing potential bias and the variety of exposures, we investigated the association between type 1 diabetes risk and nutritional and environmental exposures in pre-school children...
- Restricted fetal growth in sudden intrauterine unexplained deathJ Frederik Frøen
Department of Obstetrics and Gynecology, Rikshospitalet University Clinic, University of Oslo, Oslo, Norway
Acta Obstet Gynecol Scand 83:801-7. 2004....
- Surveillance of cesarean section deliveries, New Jersey, 1999-2004Charles E Denk
Maternal and Child Health Epidemiology Program, New Jersey Department of Health and Senior Services, Trenton, New Jersey08625 0364, USA
Birth 33:203-9. 2006..Nationally and in New Jersey, the cesarean delivery rate has been increasing steadily for nearly a decade, and especially since 1999. The purpose of this study was to describe recent trends in cesarean section delivery in New Jersey...
- Paternal age and maternal age are risk factors for miscarriage; results of a multicentre European studyElise de La Rochebrochard
INED National Demographic Studies Institute, 75020 Paris, France
Hum Reprod 17:1649-56. 2002It is well known that miscarriage risk increases with age. However, studies usually investigate only maternal age effects...
- Association between maternal age and the likelihood of a cesarean section: a population-based multivariate logistic regression analysisHerng Ching Lin
School of Health Care Administration, Taipei Medical University, Taipei, Taiwan
Acta Obstet Gynecol Scand 83:1178-83. 2004A majority of studies examining the relationship between advancing maternal age and the likelihood of cesarean section (CS) use data from regional samples or from a limited number of medical institutions...
- Maternal age and the risk of stillbirth throughout pregnancy in the United StatesUma M Reddy
Pregnancy and Perinatology Branch, National Institute of Child Health and Human Development, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, USA
Am J Obstet Gynecol 195:764-70. 2006The objective of the study was to examine the relationship of maternal age with stillbirth risk throughout gestation.
- Trends in maternal obesity and associated risks of adverse pregnancy outcomes in a population of Chinese womenT Y Leung
Department of Obstetrics and Gynaecology, The Chinese University of Hong Kong, Hong Kong, China
BJOG 115:1529-37. 2008..To assess the effect of increasing body mass index (BMI) on pregnancy outcome in a population of Chinese women...
- Indications for cesarean deliveries in NorwayToril Kolås
Department of Obstetrics and Gynecology, Lillehammer County Hospital, Norway
Am J Obstet Gynecol 188:864-70. 2003..The purpose of this study was to investigate the indications for cesarean deliveries in Norway, related to type of operation, parity, and gestational age...
- Registration of Down syndrome in the Medical Birth Registry of Norway: validity and time trendsKari Klungsøyr Melve
Department of Public Health and Primary Health Care, University of Bergen, Bergen, Norway
Acta Obstet Gynecol Scand 87:824-30. 2008..To validate Down syndrome registration in the Medical Birth Registry of Norway (MBRN), 2001-2005, and study time trends and geographical differences in Down syndrome prevalence,1967-2005...
- Trends in birth size and macrosomia in Queensland, Australia, from 1988 to 2005Petra H Lahmann
The University of Queensland, School of Population Health, Herston Qld, Australia
Paediatr Perinat Epidemiol 23:533-41. 2009..Recorded birthweight (BW, g), birth length (BL, cm), gestational age (weeks), maternal age, ethnic origin and calculated ponderal index (PI, kg/m(3)) were used...
- Increased risks of neonatal and postneonatal mortality associated with teenage pregnancy had different explanationsXi Kuan Chen
OMNI Research Group, Department of Obstetrics and Gynecology, University of Ottawa, Ottawa, Ontario, Canada K1H 8L6
J Clin Epidemiol 61:688-94. 2008..To determine the potential pathway of the association between teenage pregnancy and neonatal and postneonatal mortality...
- Socioeconomic factors and adolescent pregnancy outcomes: distinctions between neonatal and post-neonatal deaths?Barry P Markovitz
Saint Louis University School of Public Health, St, Louis, Missouri, USA
BMC Public Health 5:79. 2005Young maternal age has long been associated with higher infant mortality rates, but the role of socioeconomic factors in this association has been controversial...
- Meiotic Chromosome Segregation in C. elegansAnne Villeneuve; Fiscal Year: 2009..of the plan are highly relevant to understanding how features of chromosome organization contribute to assembly and function of the female meiotic spindle, a process that becomes increasingly error-prone with advanced maternal age.
- Meiotic Chromosome Segregation in C. elegansAnne M Villeneuve; Fiscal Year: 2010..of the plan are highly relevant to understanding how features of chromosome organization contribute to assembly and function of the female meiotic spindle, a process that becomes increasingly error-prone with advanced maternal age.
- MICRONUTRIENTS AND MOTHER TO CHILD TRANSMISSION OF HIVRichard Semba; Fiscal Year: 2001..03). Vitamin A significantly reduced low birth weight in a multivariate analysis controlling for maternal age, body mass index, and CD4+ count...
- Clinical Measures to Lower Genital Tract Trauma at BirthLeah Albers; Fiscal Year: 2004..three strategies on the likelihood of an intact perineum after birth, with control for confounding variables (maternal age and parity, birth position, style of pushing, size and position of baby at birth, length of second stage, and ..
- Maternal Morbidity and Mortality in Multiple PregnancyBarbara Luke; Fiscal Year: 2006..are limited, though, by their small sample sizes and frequent failure to control for the confounding factors of maternal age and parity...
- Plurality and Contemporary Infant Mortality RisksBarbara Luke; Fiscal Year: 2006..Older maternal age requires more aggressive therapies to achieve a pregnancy, including transferring more embryos...
- Spontaneous Arousals in "CHIME" Infants at Risk for SIDSROBERT DARNALL; Fiscal Year: 2006..In addition, important demographic data were collected including maternal age, cigarette smoking, and alcohol use...
- Quasi-experimental studies of early risk factors for severe psychopathologyPaul Lichtenstein; Fiscal Year: 2010..risk for these severe problems, including maternal smoking during pregnancy, maternal stress during pregnancy, maternal age at childbearing, and advancing paternal age at childbearing...
- THE BIODEMOGRAPHY OF HUMAN LONGEVITY--A TRAINING PROGRAMLeonid Gavrilov; Fiscal Year: 2005..importance of mutation load on the paternal X chromosome inherited by daughters only); (2) to analyze the maternal age effects on offspring longevity (in relation to the possible role of age-related accumulation of oxidative ..
- Advanced Reproductive Technology and Infant HealthMarianne Bitler; Fiscal Year: 2005..impacts of ART use and of state-mandated insurance coverage of infertility treatment on the number of births, maternal age at birth, and the incidence of multiple births, using both the NSFG and Vital Statistics birth certificate data;..
- CONTROL OF MEIOSIS AND GERMLINE PROLIFERATIONDavid Greenstein; Fiscal Year: 2009..elegans will define the signaling mechanisms controlling late events in oogenesis and provide insights into how they may go awry when signaling is perturbed. ..
- CONTROL OF MEIOSIS AND GERMLINE PROLIFERATIONDAVID I GREENSTEIN; Fiscal Year: 2010..elegans will define the signaling mechanisms controlling late events in oogenesis and provide insights into how they may go awry when signaling is perturbed. ..
- Age and molecular mechanisms contributing to aneuploidy in oocytesRichard Schultz; Fiscal Year: 2009..Most aneuplodies associated with increased maternal age are due to non-disjunction and meiotic errors that occur during meiosis...
- Ectopic Pregnancy: Assessing Long-Term Trends in Rates and Risk FactorsDelia Scholes; Fiscal Year: 2007..EP rates may not be declining; and a number of important risk factors-including tubal sterilization, advanced maternal age and Chlamydia trachomatis and other asymptomatic sexually transmitted infections -have become increasingly ..
- DIET, IMMUNE MODULATION, AND ASTHMA IN EARLY LIFEScott Weiss; Fiscal Year: 2002..potentially influential host and environmental factors to be examined include: parental asthma history, maternal age, perinatal history, acute lower respiratory illness history, day care, environmental tobacco smoke, birthweight,..
- Advanced Reproductive Age and Environmental HealthStephanie Engel; Fiscal Year: 2007..We propose to enroll 200 women of advanced maternal age (AMA) in a prospective pregnancy cohort, and to assemble a repository of maternal biological specimens ..
- Segregation of error-prone chromosomes in meiosisDean Dawson; Fiscal Year: 2007..The incidence of conceptuses with inappropriate numbers of chromosomes rises with increased maternal age. Recombination between homologous chromosomes greatly increases the probability that they will segregate ..
- Segregation of error-prone chromosomes in meiosisDean S Dawson; Fiscal Year: 2010..The incidence of conceptuses with inappropriate numbers of chromosomes rises with increased maternal age. Recombination between homologous chromosomes greatly increases the probability that they will segregate ..