age factors

Summary

Summary: Age as a constituent element or influence contributing to the production of a result. It may be applicable to the cause or the effect of a circumstance. It is used with human or animal concepts but should be differentiated from AGING, a physiological process, and TIME FACTORS which refers only to the passage of time.

Top Publications

  1. pmc Establishing a standard definition for child overweight and obesity worldwide: international survey
    T J Cole
    Department of Epidemiology and Public Health, Institute of Child Health, London WC1N 1EH
    BMJ 320:1240-3. 2000
  2. pmc The prevalence and correlates of adult ADHD in the United States: results from the National Comorbidity Survey Replication
    Ronald C Kessler
    Department of Health Care Policy, Harvard Medical School, 180 Longwood Ave, Boston, MA 02115, USA
    Am J Psychiatry 163:716-23. 2006
  3. pmc Body mass index cut offs to define thinness in children and adolescents: international survey
    Tim J Cole
    Centre for Paediatric Epidemiology and Biostatistics, UCL Institute of Child Health, London WC1N 1EH
    BMJ 335:194. 2007
  4. ncbi Cardiovascular morbidity and mortality associated with the metabolic syndrome
    B Isomaa
    Department of Internal Medicine, Jakobstad Hospital, Finland
    Diabetes Care 24:683-9. 2001
  5. ncbi Prevalence, expenditures, and complications of multiple chronic conditions in the elderly
    Jennifer L Wolff
    Department of Health Policy and Management, The Johns Hopkins University Bloomberg School of Public Health, 624 N Broadway, Room 304, Baltimore, MD 21205, USA
    Arch Intern Med 162:2269-76. 2002
  6. ncbi A more accurate method to estimate glomerular filtration rate from serum creatinine: a new prediction equation. Modification of Diet in Renal Disease Study Group
    A S Levey
    New England Medical Center, Boston, MA 02111, USA
    Ann Intern Med 130:461-70. 1999
  7. ncbi Descriptive analysis of estrogen receptor (ER)-negative, progesterone receptor (PR)-negative, and HER2-negative invasive breast cancer, the so-called triple-negative phenotype: a population-based study from the California cancer Registry
    Katrina R Bauer
    Public Health Institute California Cancer Registry, Sacramento, California 95815 4402, USA
    Cancer 109:1721-8. 2007
  8. pmc Accelerated telomere shortening in response to life stress
    Elissa S Epel
    Department of Psychiatry, University of California, 3333 California Street, Suite 465, San Francisco, CA 94143, USA
    Proc Natl Acad Sci U S A 101:17312-5. 2004
  9. ncbi Low relative skeletal muscle mass (sarcopenia) in older persons is associated with functional impairment and physical disability
    Ian Janssen
    School of Physical and Health Education, Queen s University, Kingston, Ontario, Canada
    J Am Geriatr Soc 50:889-96. 2002
  10. pmc The metabolic syndrome: prevalence and associated risk factor findings in the US population from the Third National Health and Nutrition Examination Survey, 1988-1994
    Yong Woo Park
    Department of Family Medicine, Sungkyunkwan University School of Medicine, Seoul, Korea
    Arch Intern Med 163:427-36. 2003

Detail Information

Publications241 found, 100 shown here

  1. pmc Establishing a standard definition for child overweight and obesity worldwide: international survey
    T J Cole
    Department of Epidemiology and Public Health, Institute of Child Health, London WC1N 1EH
    BMJ 320:1240-3. 2000
    ..To develop an internationally acceptable definition of child overweight and obesity, specifying the measurement, the reference population, and the age and sex specific cut off points...
  2. pmc The prevalence and correlates of adult ADHD in the United States: results from the National Comorbidity Survey Replication
    Ronald C Kessler
    Department of Health Care Policy, Harvard Medical School, 180 Longwood Ave, Boston, MA 02115, USA
    Am J Psychiatry 163:716-23. 2006
    ..Despite growing interest in adult attention deficit hyperactivity disorder (ADHD), little is known about its prevalence or correlates...
  3. pmc Body mass index cut offs to define thinness in children and adolescents: international survey
    Tim J Cole
    Centre for Paediatric Epidemiology and Biostatistics, UCL Institute of Child Health, London WC1N 1EH
    BMJ 335:194. 2007
    ..To determine cut offs to define thinness in children and adolescents, based on body mass index at age 18 years...
  4. ncbi Cardiovascular morbidity and mortality associated with the metabolic syndrome
    B Isomaa
    Department of Internal Medicine, Jakobstad Hospital, Finland
    Diabetes Care 24:683-9. 2001
    ..To estimate the prevalence of and the cardiovascular risk associated with the metabolic syndrome using the new definition proposed by the World Health Organization..
  5. ncbi Prevalence, expenditures, and complications of multiple chronic conditions in the elderly
    Jennifer L Wolff
    Department of Health Policy and Management, The Johns Hopkins University Bloomberg School of Public Health, 624 N Broadway, Room 304, Baltimore, MD 21205, USA
    Arch Intern Med 162:2269-76. 2002
    ..The prevalence, health care expenditures, and hospitalization experiences are important considerations among elderly populations with multiple chronic conditions...
  6. ncbi A more accurate method to estimate glomerular filtration rate from serum creatinine: a new prediction equation. Modification of Diet in Renal Disease Study Group
    A S Levey
    New England Medical Center, Boston, MA 02111, USA
    Ann Intern Med 130:461-70. 1999
    ..Serum creatinine concentration is widely used as an index of renal function, but this concentration is affected by factors other than glomerular filtration rate (GFR)...
  7. ncbi Descriptive analysis of estrogen receptor (ER)-negative, progesterone receptor (PR)-negative, and HER2-negative invasive breast cancer, the so-called triple-negative phenotype: a population-based study from the California cancer Registry
    Katrina R Bauer
    Public Health Institute California Cancer Registry, Sacramento, California 95815 4402, USA
    Cancer 109:1721-8. 2007
    ..The triple-negative phenotype is important because of its relation to the basal-like subtype of breast cancer...
  8. pmc Accelerated telomere shortening in response to life stress
    Elissa S Epel
    Department of Psychiatry, University of California, 3333 California Street, Suite 465, San Francisco, CA 94143, USA
    Proc Natl Acad Sci U S A 101:17312-5. 2004
    ..These findings have implications for understanding how, at the cellular level, stress may promote earlier onset of age-related diseases...
  9. ncbi Low relative skeletal muscle mass (sarcopenia) in older persons is associated with functional impairment and physical disability
    Ian Janssen
    School of Physical and Health Education, Queen s University, Kingston, Ontario, Canada
    J Am Geriatr Soc 50:889-96. 2002
    ..To establish the prevalence of sarcopenia in older Americans and to test the hypothesis that sarcopenia is related to functional impairment and physical disability in older persons...
  10. pmc The metabolic syndrome: prevalence and associated risk factor findings in the US population from the Third National Health and Nutrition Examination Survey, 1988-1994
    Yong Woo Park
    Department of Family Medicine, Sungkyunkwan University School of Medicine, Seoul, Korea
    Arch Intern Med 163:427-36. 2003
    ..The extent to which the metabolic syndrome is associated with demographic and potentially modifiable lifestyle factors in the US population is unknown...
  11. ncbi How many steps/day are enough? Preliminary pedometer indices for public health
    Catrine Tudor-Locke
    Department of Exercise and Wellness, Arizona State University, Mesa, Arizona 85212, USA
    Sports Med 34:1-8. 2004
    ..or=10000 steps/day indicates the point that should be used to classify individuals as 'active'. Individuals who take >12500 steps/day are likely to be classified as 'highly active'...
  12. pmc Age-patterns of malaria vary with severity, transmission intensity and seasonality in sub-Saharan Africa: a systematic review and pooled analysis
    Ilona Carneiro
    Disease Control and Vector Biology Unit, Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom
    PLoS ONE 5:e8988. 2010
    ..We have, therefore, undertaken a pooled analysis of existing data from multiple sites to enable a comprehensive overview of the age-patterns of malaria outcomes under different epidemiological conditions in sub-Saharan Africa...
  13. ncbi Prevalence, co-morbidity and correlates of mental disorders in the general population: results from the German Health Interview and Examination Survey (GHS)
    F Jacobi
    Institute of Clinical Psychology and Psychotherapy, Unit Epidemiology and Service Research, Technical University of Dresden, Germany
    Psychol Med 34:597-611. 2004
    ..This paper reports results from its Mental Health Supplement (GHS-MHS) on 4-week 12-month, and selected lifetime prevalence of a broad range of DSM-IV mental disorders, their co-morbidity and correlates in the community...
  14. doi Worldwide stroke incidence and early case fatality reported in 56 population-based studies: a systematic review
    Valery L Feigin
    National Research Centre for Stroke, Applied Neurosciences and Neurorehabilitation, School of Rehabilitation and Occupation Studies, AUT University, North Shore Campus, AA254, Northcote 0627, Auckland 1142, New Zealand
    Lancet Neurol 8:355-69. 2009
    ..The time to decide whether or not stroke is an issue that should be on the governmental agenda in low to middle income countries has now passed. Now is the time for action...
  15. ncbi Health-related quality of life in total hip and total knee arthroplasty. A qualitative and systematic review of the literature
    Olivier Ethgen
    WHO Collaborating Center for Public Health Aspects of Osteoarticular Diseases, Department of Public Health, Epidemiology, and Health Economics, University of Liege, Belgium, Liege, Belgium
    J Bone Joint Surg Am 86:963-74. 2004
    ..The objective of this study was to review the literature regarding the outcomes of total hip and knee arthroplasties as evaluated by health-related quality-of-life instruments...
  16. pmc Genome-wide association studies identify loci associated with age at menarche and age at natural menopause
    Chunyan He
    Program in Molecular and Genetic Epidemiology, Harvard School of Public Health, Boston, Massachusetts, USA
    Nat Genet 41:724-8. 2009
    ..42 (in or near the gene BRSK1), 5q35.2 (in or near genes UIMC1 and HK3) and 6p24.2 (in the gene SYCP2L). These newly identified loci might expand understanding of the biological pathways regulating these two traits...
  17. doi The completeness of the Swedish Cancer Register: a sample survey for year 1998
    Lotti Barlow
    Centre for Epidemiology, The National Board of Health and Welfare, Stockholm, Sweden
    Acta Oncol 48:27-33. 2009
    ..The aim of the study was to estimate the overall coverage of malignant cancer cases in 1998 and to reveal possible reasons behind non-reporting...
  18. ncbi Lifetime prevalence and age-of-onset distributions of DSM-IV disorders in the National Comorbidity Survey Replication
    Ronald C Kessler
    Department of Health Care Policy, Harvard Medical School, Boston, Massachusetts 02115, USA
    Arch Gen Psychiatry 62:593-602. 2005
    ..Little is known about lifetime prevalence or age of onset of DSM-IV disorders...
  19. doi Neurodevelopmental trajectories of the human cerebral cortex
    Philip Shaw
    Child Psychiatry Branch, National Institute of Mental Health, Bethesda, Maryland 20892, USA
    J Neurosci 28:3586-94. 2008
    ....
  20. pmc DNA methylation profiling of human chromosomes 6, 20 and 22
    Florian Eckhardt
    Epigenomics AG, Kleine Präsidentstrasse 1, 10178 Berlin, Germany
    Nat Genet 38:1378-85. 2006
    ..Our data suggest DNA methylation to be ontogenetically more stable than previously thought...
  21. ncbi Aging is associated with decreased maximal life span and accelerated senescence of bone marrow stromal cells
    Karin Stenderup
    University Department of Endocrinology and Metabolism, University Hospital of Aarhus, DK 8000 Aarhus C, Denmark
    Bone 33:919-26. 2003
    ..In conclusion, aging is associated with decreased proliferative capacity of osteoprogenitor cells, suggesting that decreased osteoblastic cell number, and not function, leads to age-related decrease in bone formation...
  22. ncbi Heat stress and public health: a critical review
    R Sari Kovats
    Public and Environmental Health Research Unit PEHRU, London School of Hygiene and Tropical Medicine, London, UK
    Annu Rev Public Health 29:41-55. 2008
    ....
  23. ncbi Trends of obesity and underweight in older children and adolescents in the United States, Brazil, China, and Russia
    Youfa Wang
    Carolina Population Center, School of Public Health, University of North Carolina, Chapel Hill 27516 3997, USA
    Am J Clin Nutr 75:971-7. 2002
    ..Few studies have used the same references across countries to examine the trends of over- and underweight in older children and adolescents...
  24. pmc Short sleep duration and weight gain: a systematic review
    Sanjay R Patel
    Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, University Hospitals Case Medical Center and Case Western Reserve University, Cleveland, OH, USA
    Obesity (Silver Spring) 16:643-53. 2008
    ..This work reviews the literature regarding short sleep duration as an independent risk factor for obesity and weight gain...
  25. ncbi Ptf1a, a bHLH transcriptional gene, defines GABAergic neuronal fates in cerebellum
    Mikio Hoshino
    Department of Pathology and Tumor Biology, Graduate School of Medicine, Kyoto University, Sakyo ku, Kyoto 606 8501, Japan
    Neuron 47:201-13. 2005
    ..Our results suggest that Ptf1a is involved in driving neural precursors to differentiate into GABAergic neurons in the cerebellum...
  26. pmc The association between glucometabolic disturbances, traditional cardiovascular risk factors and self-rated health by age and gender: a cross-sectional analysis within the Malmö Preventive Project
    Margret Leosdottir
    Department of Cardiology, Skane University Hospital, and Heart Health Group Department of Clinical Sciences, Lund University, Malmo, Sweden
    Cardiovasc Diabetol 10:118. 2011
    ..Whether this age-related reduction applies to CVD risk factors, and whether it is limited to established diabetes mellitus (DM) or also applies to pre-diabetic conditions are not well known...
  27. pmc Cardiometabolic risk variables in overweight and obese children: a worldwide comparison
    Mariska van Vliet
    Department of Pediatrics, Slotervaart Hospital, Louwesweg 6, 1066 EC, Amsterdam, The Netherlands
    Cardiovasc Diabetol 10:106. 2011
    ..The results of our review present a fair estimation of the true differences between cardiometabolic risk profiles among pediatric cohorts worldwide, based on available literature...
  28. ncbi Regional brain changes in aging healthy adults: general trends, individual differences and modifiers
    Naftali Raz
    Department of Psychology and Institute of Gerontology, Wayne State University, 87 East Ferry St, 226 Knapp Building, Detroit, MI 48202, USA
    Cereb Cortex 15:1676-89. 2005
    ..No sex differences in age trends except for the caudate were observed. We found no evidence of neuroprotective effects of larger brain size or educational attainment...
  29. ncbi Sexual behaviour in context: a global perspective
    Kaye Wellings
    London School of Hygiene and Tropical Medicine, London WC1E 7HT, UK
    Lancet 368:1706-28. 2006
    ....
  30. ncbi The prevalence of pain and pain interference in a general population of older adults: cross-sectional findings from the North Staffordshire Osteoarthritis Project (NorStOP)
    Elaine Thomas
    Primary Care Sciences Research Centre, Keele University, Keele, North Staffordshire, ST5 5BG, UK
    Pain 110:361-8. 2004
    ..More importantly the extent to which pain interferes with everyday life increases incrementally with age up to the oldest age-group in the community-dwelling general population...
  31. pmc The challenge of comprehensively mapping children's health in a nation-wide health survey: design of the German KiGGS-Study
    Bärbel Maria Kurth
    Department of Epidemiology and Health Reporting, Robert Koch Institute, Seestrasse 10, 13353 Berlin, Germany
    BMC Public Health 8:196. 2008
    ..Aim of this first nationwide interview and examination survey was to collect comprehensive data on the health status of children and adolescents aged 0 to 17 years...
  32. pmc If started early in life, metformin treatment increases life span and postpones tumors in female SHR mice
    Vladimir N Anisimov
    N N Petrov Research Institute of Oncology, Pesochny 2, St Petersburg, Russia
    Aging (Albany NY) 3:148-57. 2011
    ..Thus, in female SHR mice, metformin increased life span and postponed tumors when started at the young and middle but not at the old age. In contrast, metformin improves reproductive function when started at any age...
  33. pmc A large-scale candidate gene association study of age at menarche and age at natural menopause
    Chunyan He
    Department of Public Health, Indiana University School of Medicine, Indianapolis, IN, USA
    Hum Genet 128:515-27. 2010
    ..013), and the group of genes involved in premature ovarian failure with age at menopause (P = 0.025)...
  34. ncbi The timing of normal puberty and the age limits of sexual precocity: variations around the world, secular trends, and changes after migration
    Anne Simone Parent
    Division of Ambulatory Pediatrics and Adolescent Medicine, University of Liege, B 4000 Liege, Belgium
    Endocr Rev 24:668-93. 2003
    ....
  35. pmc Human CD4+ T cell recent thymic emigrants are identified by protein tyrosine kinase 7 and have reduced immune function
    Christopher J Haines
    Department of Pediatrics and the Immunology Program, Stanford University, Stanford, CA 94305, USA
    J Exp Med 206:275-85. 2009
    ..The ability to identify viable CD4(+) RTEs by PTK7 staining should be useful for monitoring thymic output in both healthy individuals and in patients with genetic or acquired CD4(+) T cell immunodeficiencies...
  36. ncbi Obesity and vascular risk factors at midlife and the risk of dementia and Alzheimer disease
    Miia Kivipelto
    Aging Research Center, Division of Geriatric Epidemiology, Neurotec, Karolinska Institutet, Stockholm, Sweden
    Arch Neurol 62:1556-60. 2005
    ..Vascular risk factors play a role in the development of dementia, including Alzheimer disease (AD). However, little is known about the effect of body mass index and clustering of vascular risk factors on the development of dementia...
  37. pmc Multimorbidity patterns in the elderly: a new approach of disease clustering identifies complex interrelations between chronic conditions
    Ingmar Schafer
    Department of Primary Medical Care, University Medical Center Hamburg Eppendorf, Hamburg, Germany
    PLoS ONE 5:e15941. 2010
    ..The aim of this study was to increase the knowledge of specific processes of multimorbidity in an unselected elderly population by identifying patterns of statistically significantly associated comorbidity...
  38. pmc Antiretroviral therapy adherence, virologic and immunologic outcomes in adolescents compared with adults in southern Africa
    Jean B Nachega
    Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
    J Acquir Immune Defic Syndr 51:65-71. 2009
    ..To determine adherence to and effectiveness of antiretroviral therapy (ART) in adolescents vs. adults in southern Africa...
  39. ncbi Longitudinal magnetic resonance imaging studies of older adults: a shrinking brain
    Susan M Resnick
    Laboratory of Personality and Cognition, National Institute on Aging, Baltimore, Maryland 21224 6825, USA
    J Neurosci 23:3295-301. 2003
    ....
  40. doi High temperature and hospitalizations for cardiovascular and respiratory causes in 12 European cities
    Paola Michelozzi
    Department of Epidemiology Local Health Authority Rome E, Rome, Italy
    Am J Respir Crit Care Med 179:383-9. 2009
    ..Episode analyses of heat waves have documented a comparatively higher impact on mortality than on morbidity (hospital admissions) in European cities. The evidence from daily time series studies is scarce and inconsistent...
  41. doi Moderate-to-vigorous physical activity from ages 9 to 15 years
    Philip R Nader
    Department of Pediatrics, University of California San Diego, 9500 Gilman Dr, La Jolla, CA 92093 0927, USA
    JAMA 300:295-305. 2008
    ..Although at least 60 minutes per day of moderate-to-vigorous physical activity (MVPA) is recommended, few longitudinal studies have determined the recent patterns of physical activity of youth...
  42. pmc Survival of HIV-infected adolescents on antiretroviral therapy in Uganda: findings from a nationally representative cohort in Uganda
    Celestin Bakanda
    The AIDS Support Organization, Kampala, Uganda
    PLoS ONE 6:e19261. 2011
    ..Adolescents have been identified as a high-risk group for poor adherence to and defaulting from combination antiretroviral therapy (cART) care. However, data on outcomes for adolescents on cART in resource-limited settings remain scarce...
  43. ncbi Variations in patients' adherence to medical recommendations: a quantitative review of 50 years of research
    M Robin Dimatteo
    Department of Psychology, University of California, Riverside, CA 92521, USA
    Med Care 42:200-9. 2004
    ..The literature on patient adherence to treatment includes hundreds of empirical studies. A comprehensive examination of the findings requires the organization and quantification that is possible with meta-analysis...
  44. ncbi Anemia is associated with disability and decreased physical performance and muscle strength in the elderly
    Brenda W J H Penninx
    Sticht Center on Aging, Section on Gerontology and Geriatric Medicine, Wake Forest University School of Medicine, Winston Salem, North Carolina, USA
    J Am Geriatr Soc 52:719-24. 2004
    ..To examine the association between anemia and disability, physical performance, and muscle strength in older persons...
  45. pmc Limited efficacy of inactivated influenza vaccine in elderly individuals is associated with decreased production of vaccine-specific antibodies
    Sanae Sasaki
    Department of Immunology and Microbiology, Stanford University School of Medicine, Stanford, California, USA
    J Clin Invest 121:3109-19. 2011
    ..They also suggest that exposure history affects the cross-reactivity of vaccination-induced antibodies...
  46. ncbi Obesity, regional body fat distribution, and the metabolic syndrome in older men and women
    Bret H Goodpaster
    Department of Medicine, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
    Arch Intern Med 165:777-83. 2005
    ..We determined whether patterns of regional fat deposition are associated with metabolic syndrome in older adults...
  47. pmc Statistical methods for the time-to-event analysis of individual participant data from multiple epidemiological studies
    Simon Thompson
    MRC Biostatistics Unit, Institute of Public Health, Cambridge, UK
    Int J Epidemiol 39:1345-59. 2010
    ..Meta-analysis of individual participant time-to-event data from multiple prospective epidemiological studies enables detailed investigation of exposure-risk relationships, but involves a number of analytical challenges...
  48. ncbi The relationship between serum uric acid level and metabolic syndrome: differences by sex and age in Taiwanese
    Wen Ko Chiou
    Department of Industrial Design, Chang Gung University, Kweishan, Taoyuan, Taiwan, ROC
    J Epidemiol 20:219-24. 2010
    ..This study was performed to explore the potential value of UA level as a marker of MetS among male and female Chinese of different ages...
  49. ncbi Metformin extends life span of HER-2/neu transgenic mice and in combination with melatonin inhibits growth of transplantable tumors in vivo
    Vladimir N Anisimov
    N N Petrov Research Institute of Oncology, St Petersburg, Russia
    Cell Cycle 9:188-97. 2010
    ..001). The combined treatment with metformin + melatonin significantly suppressed Ehrlich tumor growth (by 40%, p < 0.001). These results suggest that metformin may be useful in prevention and treatment of breast cancer...
  50. pmc Meta-analyses identify 13 loci associated with age at menopause and highlight DNA repair and immune pathways
    Lisette Stolk
    Department of Internal Medicine, Erasmus MC, Rotterdam, The Netherlands
    Nat Genet 44:260-8. 2012
    ..Gene-set enrichment pathway analyses using the full GWAS data set identified exoDNase, NF-κB signaling and mitochondrial dysfunction as biological processes related to timing of menopause...
  51. ncbi Can parents rate their child's health-related quality of life? Results of a systematic review
    C Eiser
    Department of Psychology, University of Sheffield, Western Bank, UK
    Qual Life Res 10:347-57. 2001
    ..All of these results may be dependent on the specific measure of HRQoL employed. There remain strong arguments for obtaining information from both parents and children whenever possible...
  52. ncbi Prediction of lifetime risk for cardiovascular disease by risk factor burden at 50 years of age
    Donald M Lloyd-Jones
    Department of Preventive Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA
    Circulation 113:791-8. 2006
    ..Lifetime risk for atherosclerotic cardiovascular disease (CVD) has not previously been estimated, and the effect of risk factor burden on lifetime risk is unknown...
  53. pmc Plasmodium infection and its risk factors in eastern Uganda
    Rachel L Pullan
    Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, UK
    Malar J 9:2. 2010
    ..This report presents results from a total population survey of malaria infection and intervention coverage in a rural area of eastern Uganda, with a specific focus on how risk factors differ between demographic groups in this population...
  54. pmc Self rated health: Is it as good a predictor of subsequent mortality among adults in lower as well as in higher social classes?
    B Burstrom
    Department of Public Health Sciences, Division of Social Medicine, Karolinska Institutet, SE 171 76 Stockholm, Sweden
    J Epidemiol Community Health 55:836-40. 2001
    ..To analyse the predictive power of self rated health for mortality in different socioeconomic groups...
  55. pmc Household transmission of 2009 pandemic influenza A (H1N1) virus in the United States
    Simon Cauchemez
    Medical Research Council Centre for Outbreak Analysis and Modelling, Department of Infectious Disease Epidemiology, Imperial College London, London
    N Engl J Med 361:2619-27. 2009
    ..Risk factors for transmission remain largely uncharacterized. We characterize the risk factors and describe the transmission of the virus within households...
  56. ncbi Comparing rat's to human's age: how old is my rat in people years?
    Robert Quinn
    Nutrition 21:775-7. 2005
  57. pmc Immuno-epidemiologic correlates of pandemic H1N1 surveillance observations: higher antibody and lower cell-mediated immune responses with advanced age
    Danuta M Skowronski
    British Columbia Centre for Disease Control, Vancouver, BC, V5Z 4R4, Canada
    J Infect Dis 203:158-67. 2011
    ..Pandemic H1N1 (pH1N1) surveillance data showed lower attack rates but higher risk of severe outcomes with advanced age. We explored immuno-epidemiologic correlates of surveillance findings including humoral and cell-mediated immunity (CMI)...
  58. ncbi Mortality after osteoporotic fractures
    O Johnell
    Department of Orthopaedics, Malmo University Hospital, Malmo, Sweden
    Osteoporos Int 15:38-42. 2004
    ..The decreasing mortality with time after fracture may be due in part to a decrease in deaths causally related to the fracture. The extent to which early intervention for osteoporosis might avoid some of these deaths is unknown...
  59. doi Association between age at menarche and risk of diabetes in adults: results from the EPIC-Norfolk cohort study
    R Lakshman
    MRC Epidemiology Unit, Institute of Metabolic Science, Addenbrooke s Hospital, Box 285, Cambridge, CB2 0QQ, UK
    Diabetologia 51:781-6. 2008
    ..Earlier age at menarche is associated with increased BMI and obesity risk from early childhood through to adulthood. We hypothesised that earlier age at menarche would also predict subsequent diabetes risk...
  60. ncbi Executive function and the frontal lobes: a meta-analytic review
    Julie A Alvarez
    Department of Psychology, Emory University, Atlanta, GA 30322, USA
    Neuropsychol Rev 16:17-42. 2006
    ..The paper concludes with a discussion of the implications of construing the validity of these neuropsychological tests in anatomical, rather than cognitive and behavioral, terms...
  61. doi Sequential, ordered acquisition of antibodies to Plasmodium falciparum erythrocyte membrane protein 1 domains
    Gerald K K Cham
    Centre for Medical Parasitology at Department of International Health, Immunology, and Microbiology, University of Copenhagen, Copenhagen University Hospital, Copenhagen, Denmark
    J Immunol 183:3356-63. 2009
    ..The identification of PfEMP1 domains expressed by parasites causing disease in infants and young children is important for development of vaccines protecting against severe malaria...
  62. pmc Gender differences in metformin effect on aging, life span and spontaneous tumorigenesis in 129/Sv mice
    Vladimir N Anisimov
    N N Petrov Research Institute of Oncology, Pesochny 2, St Petersburg 197758, Russia
    Aging (Albany NY) 2:945-58. 2010
    ..5 times the incidence of malignant neoplasms in female mice while somewhat stimulated formation of benign vascular tumors in the latter...
  63. ncbi Destructive periodontal disease in adults 30 years of age and older in the United States, 1988-1994
    J M Albandar
    National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, MD, USA
    J Periodontol 70:13-29. 1999
    ..This study estimated the prevalence and extent of periodontal disease in the United States using data from the third National Health and Nutrition Examination Survey (NHANES III)...
  64. pmc Loci at chromosomes 13, 19 and 20 influence age at natural menopause
    Lisette Stolk
    Department of Internal Medicine, Erasmus MC, Rotterdam, The Netherlands
    Nat Genet 41:645-7. 2009
    ..5 year per A allele (12%); P = 2.5 × 10(-8)). These common genetic variants regulate timing of ovarian aging, an important risk factor for breast cancer, osteoporosis and cardiovascular disease...
  65. ncbi Undertreatment strongly decreases prognosis of breast cancer in elderly women
    Christine Bouchardy
    Geneva Cancer Registry, 55 Boulevard de la Cluse 55, 1205 Geneva, Switzerland
    J Clin Oncol 21:3580-7. 2003
    ..Treatments are influenced by unclear standards and are usually less aggressive. This study aims to evaluate determinants and effect of treatment choice on breast cancer prognosis among elderly patients...
  66. pmc Age-related somatic structural changes in the nuclear genome of human blood cells
    Lars A Forsberg
    Department of Immunology, Genetics and Pathology, Rudbeck Laboratory, Uppsala University, Sweden
    Am J Hum Genet 90:217-28. 2012
    ..Our work might also help to explain the cause of an age-related reduction in the number of cell clones in the blood; such a reduction is one of the hallmarks of immunosenescence...
  67. ncbi Age at menarche and adult BMI in the Aberdeen children of the 1950s cohort study
    Mary B Pierce
    London School of Hygiene and Tropical Medicine, London, United Kingdom
    Am J Clin Nutr 82:733-9. 2005
    ....
  68. ncbi Prevalence of anemia in persons 65 years and older in the United States: evidence for a high rate of unexplained anemia
    Jack M Guralnik
    Laboratory of Epidemiology, Demography, and Biometry, National Institute on Aging, 7201 Wisconsin Ave, Rm 3C 309, Bethesda, MD 20815, USA
    Blood 104:2263-8. 2004
    ..The impact of anemia on quality of life, recovery from illness, and functional abilities must be further investigated in older persons...
  69. ncbi The Colorado thyroid disease prevalence study
    G J Canaris
    Department of Medicine, University of Nebraska Medical Center, Omaha 68198 3331, USA
    Arch Intern Med 160:526-34. 2000
    ..Systemic effects of abnormal thyroid function have not been fully delineated, particularly in cases of mild thyroid failure. Also, the relationship between traditional hypothyroid symptoms and biochemical thyroid function is unclear...
  70. ncbi Using data on social contacts to estimate age-specific transmission parameters for respiratory-spread infectious agents
    Jacco Wallinga
    National Institute for Public Health and the Environment, Bilthoven, The Netherlands
    Am J Epidemiol 164:936-44. 2006
    ..These findings have important implications for controlling future outbreaks of novel respiratory-spread infectious agents...
  71. doi Excess mortality following hip fracture: a systematic epidemiological review
    B Abrahamsen
    Department of Internal Medicine and Endocrinology, Copenhagen University Hospital Gentofte, Niels Andersensvej 65, 2900, Hellerup, Denmark
    Osteoporos Int 20:1633-50. 2009
    ....
  72. doi Delaying bacillus Calmette-Guérin vaccination from birth to 4 1/2 months of age reduces postvaccination Th1 and IL-17 responses but leads to comparable mycobacterial responses at 9 months of age
    Sarah Burl
    Medical Research Council United Kingdom, The Gambia, Fajara, The Gambia, West Africa
    J Immunol 185:2620-8. 2010
    ..The evidence did not suggest that mycobacterial specific naturally occurring Tregs accounted for this attenuated immunogenicity...
  73. ncbi Aging in the CNS: comparison of gray/white matter volume and diffusion tensor data
    Osamu Abe
    Department of Radiology, Graduate School of Medicine, University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo 113 8655, Japan
    Neurobiol Aging 29:102-16. 2008
    ..These results indicate that diffusion properties and brain volume are complementary markers to the effects of aging...
  74. pmc Pet-1 is required across different stages of life to regulate serotonergic function
    Chen Liu
    Case Western Reserve University, School of Medicine, Department of Neurosciences, Cleveland, Ohio, USA
    Nat Neurosci 13:1190-8. 2010
    ..These findings indicate that Pet-1 is required across the lifespan of the mouse and that behavioral pathogenesis can result from both developmental and adult-onset alterations in serotonergic transcription...
  75. pmc The boomers are coming: a total cost of care model of the impact of population aging on health care costs in the United States by Major Practice Category
    E Mary Martini
    Health Informatics, HealthPartners, 8170 33rd Ave S, Mail Stop 21108Q, Minneapolis, MN 55440 1309, USA
    Health Serv Res 42:201-18. 2007
    ..To project the impact of population aging on total U.S. health care per capita costs from 2000 to 2050 and for the range of clinical areas defined by Major Practice Categories (MPCs)...
  76. ncbi Corneal crystals in nephropathic cystinosis: natural history and treatment with cysteamine eyedrops
    W A Gahl
    Section on Human Biochemical Genetics, Heritable Disorders Branch, National Institute of Child Health and Human Development, Bethesda, Maryland 20892, USA
    Mol Genet Metab 71:100-20. 2000
    ..Administration of 0.55% cysteamine eyedrops, given 6 to 12 times per day, dissolved corneal cystine crystals in 10 representative patients with nephropathic cystinosis aged 1 to 32 years within 8 to 41 months...
  77. doi Hospitalization for pneumonia among individuals with and without HIV infection, 1995-2007: a Danish population-based, nationwide cohort study
    Ole S Sogaard
    Department of Infectious Diseases, Aarhus University Hospital, Skejby, Denmark
    Clin Infect Dis 47:1345-53. 2008
    ..We compared incidence rates of pneumonia among individuals with and without HIV infection and explored risk factors for pneumonia in the HIV-infected population...
  78. pmc The absence of coronary calcification does not exclude obstructive coronary artery disease or the need for revascularization in patients referred for conventional coronary angiography
    Ilan Gottlieb
    Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    J Am Coll Cardiol 55:627-34. 2010
    ..This study was designed to evaluate whether the absence of coronary calcium could rule out >or=50% coronary stenosis or the need for revascularization...
  79. ncbi Chest injury due to blunt trauma
    Serife Tuba Liman
    General Thoracic Surgery Department, Atatürk Center for Chest Diseases and Thoracic Surgery, Ankara, Turkey
    Eur J Cardiothorac Surg 23:374-8. 2003
    ..Given its importance in trauma practice, we aimed to determine the pathologies associated with blunt chest injuries and to analyze the accurate identification of patients at high risk for major chest trauma...
  80. doi Females exhibit more extensive amyloid, but not tau, pathology in an Alzheimer transgenic model
    Chiho Hirata-Fukae
    Department of Neurology, Georgetown University Medical Center, Washington, DC 20057, USA
    Brain Res 1216:92-103. 2008
    ..These findings confirm progressive Abeta pathology in 3xTg-AD transgenic mice, and provide guidance for their use in therapeutic research...
  81. pmc Paradoxical anxiogenic response of juvenile mice to fluoxetine
    Ji Eun Oh
    Department of Pharmacology, Weill Medical College of Cornell University, New York, NY 10021, USA
    Neuropsychopharmacology 34:2197-207. 2009
    ....
  82. doi Energy imbalance underlying the development of childhood obesity
    Nancy F Butte
    USDA ARS Children s Nutrition Research Center, Department of Pediatrics, Baylor College of Medicine, 1100 Bates Street, Houston, TX 77030, USA
    Obesity (Silver Spring) 15:3056-66. 2007
    ....
  83. pmc Estimation and projection of the national profile of cancer mortality in China: 1991-2005
    L Yang
    International Agency for Research on Cancer, 150 cours Albert Thomas, 69372 Lyon Cedex 08, France
    Br J Cancer 90:2157-66. 2004
    ....
  84. doi The predictive value of different measures of obesity for incident cardiovascular events and mortality
    Harald J Schneider
    Medizinische Klinik Innenstadt, Ludwig Maximilians University, Ziemssenstrasse 1, 80336 Munich, Germany
    J Clin Endocrinol Metab 95:1777-85. 2010
    ..To date, it is unclear which measure of obesity is the most appropriate for risk stratification...
  85. ncbi Age-dependent motor deficits and dopaminergic dysfunction in DJ-1 null mice
    Linan Chen
    Department of Neurobiology, Pharmacology and Physiology, The University of Chicago, Chicago, Illinois 60637, USA
    J Biol Chem 280:21418-26. 2005
    ..These data represent the in vivo evidence that loss of DJ-1 function alters nigrostriatal dopaminergic function and produces motor deficits...
  86. pmc Telomere length and heredity: Indications of paternal inheritance
    Katarina Nordfjäll
    Units for Pathology and Medical and Clinical Genetics, Department of Medical Biosciences, Umea University, SE 90187 Umea, Sweden
    Proc Natl Acad Sci U S A 102:16374-8. 2005
    ..Telomere length is inherited, and evidence for a father-to-offspring heritage of this trait was obtained, whereas in vitro telomere length maintenance was found to be dependent on the initial telomere length...
  87. ncbi Bronchopulmonary dysplasia in very low birth weight subjects and lung function in late adolescence
    Lex W Doyle
    Department of Obstetrics and Gynecology, University of Melbourne, Melbourne, Australia
    Pediatrics 118:108-13. 2006
    ....
  88. ncbi Gastrointestinal stromal tumors: the incidence, prevalence, clinical course, and prognostication in the preimatinib mesylate era--a population-based study in western Sweden
    Bengt Nilsson
    Department of Surgery, The Lundberg Laboratory for Cancer Research, Sahlgrenska Academy at the University of Göteborg, Goteborg, Sweden
    Cancer 103:821-9. 2005
    ..New treatment options mandate more accurate information regarding the incidence, prevalence, clinical behavior, and prognostic factors of GIST...
  89. ncbi Older stroke patients in Europe: stroke care and determinants of outcome
    A Bhalla
    Department of Public Health Sciences, GKT School of Medicine, London, UK
    Age Ageing 33:618-24. 2004
    ..in order to implement cost-effective stroke services for older patients, it is necessary to identify how stroke care is currently provided for these patients and how provision relates to outcome...
  90. pmc The changing global patterns of female breast cancer incidence and mortality
    Freddie Bray
    Unit of Descriptive Epidemiology, International Agency for Research on Cancer, Lyon, France
    Breast Cancer Res 6:229-39. 2004
    ..The observations are discussed in the context of the numerous aetiological factors, as well as the impact of screening and advances in treatment and disease management in high-resource settings...
  91. ncbi Executive functioning as a potential mediator of age-related cognitive decline in normal adults
    Timothy A Salthouse
    Dept of Psychology, University of Virginia, Charlottesville, VA 22904 4400, USA
    J Exp Psychol Gen 132:566-94. 2003
    ....
  92. doi Testing ovarian reserve to predict age at menopause
    C B Lambalk
    Division of Reproductive Medicine, Department of Obstetrics Gynaecology, Vrije Universiteit Medical Center, Amsterdam, The Netherlands
    Maturitas 63:280-91. 2009
    ..Results of new and ongoing longitudinal studies may provide better predictive models. In particular, use of genetic profiles may add to the accuracy of currently known markers...
  93. ncbi Minocycline delays disease onset and mortality in a transgenic model of ALS
    Ludo Van Den Bosch
    Laboratory for Neurobiology, Campus Gasthuisberg, Herestraat 49, B 3000 Leuven, Belgium
    Neuroreport 13:1067-70. 2002
    ..These results demonstrate that interference with immuno-inflammatory responses has a beneficial effect in the ALS mice model, suggesting this to be a potential new strategy to treat ALS...
  94. ncbi Greater effect of highly active antiretroviral therapy on survival in people aged > or =50 years compared with younger people in an urban observational cohort
    John L Perez
    Division of Infectious Diseases, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA
    Clin Infect Dis 36:212-8. 2003
    ..28 (95% CI, 0.15-0.52) for treated older adults. The effect of HAART substantially improves the survival rate for older individuals and supports the importance of treatment in this group...
  95. ncbi Midlife blood pressure and dementia: the Honolulu-Asia aging study
    L J Launer
    Epidemiology, Demography and Biometry Program, National Institute on Aging, National Institutes of Health, Gateway Building 3C 309, 7201 Wisconsin Avenue, Bethesda, MD 20892, USA
    Neurobiol Aging 21:49-55. 2000
    ..This study suggests elevated levels of blood pressure in middle age can increase the risk for late age dementia in men never treated with anti-hypertensive medication...
  96. doi Diabetes and cancer: a consensus report
    Edward Giovannucci
    Departments of Nutrition and Epidemiology, Harvard School of Public Health, 655 Huntington Avenue, Boston, MA 02115, USA
    CA Cancer J Clin 60:207-21. 2010
    ..In addition, key unanswered questions for future research are posed...
  97. ncbi Preventing myocardial infarction in the young adult in the first place: how do the National Cholesterol Education Panel III guidelines perform?
    Kwame O Akosah
    Gundersen Lutheran Medical Foundation, La Crosse, Wisconsin 54601, USA
    J Am Coll Cardiol 41:1475-9. 2003
    ..The purpose of this study was to investigate the utility of the new National Cholesterol Education Program (NCEP) III guidelines in a group of young adults...
  98. pmc Variation in use of erythrocyte invasion pathways by Plasmodium falciparum mediates evasion of human inhibitory antibodies
    Kristina E M Persson
    The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia
    J Clin Invest 118:342-51. 2008
    ..falciparum and that a broad inhibitory response against multiple ligands may be required for effective immunity...
  99. pmc The DNA damage response: Balancing the scale between cancer and ageing
    Elena G Seviour
    Department of Systems, Biology, M D Anderson Cancer Center, Houston, TX 77054, USA
    Aging (Albany NY) 2:900-7. 2010
    ..While the removal of cells containing damaged DNA can be beneficial in the prevention of cancer, it may contribute to both normal and pathological ageing...
  100. ncbi National trends in the outpatient diagnosis and treatment of bipolar disorder in youth
    Carmen Moreno
    Unidad de Adolescentes, Hospital General Universitario Gregorio Maranon, Servicio do Psiquiatría, Madrid, Spain
    Arch Gen Psychiatry 64:1032-9. 2007
    ..Although bipolar disorder may have its onset during childhood, little is known about national trends in the diagnosis and management of bipolar disorder in young people...
  101. ncbi Prevalence and development of psychiatric disorders in childhood and adolescence
    E Jane Costello
    Department of Psychiatry and Behavioral Sciences, Duke University Medical School, Durham, NC 27710, USA
    Arch Gen Psychiatry 60:837-44. 2003
    ..This longitudinal community study assessed the prevalence and development of psychiatric disorders from age 9 through 16 years and examined homotypic and heterotypic continuity...

Research Grants206 found, 100 shown here

  1. DEMOGRAPHIC STUDY OF MULTIPLE CAUSES OF DEATH
    Kenneth Manton; Fiscal Year: 1993
    ..As such the analyses will be cohort based with parameterization to detect specific period effects. Statistical tests will be conducted using likelihood ratio principles...
  2. The role of mental health, support and coping on the HIV risk protective and prom
    David J Malebranche; Fiscal Year: 2010
    ....
  3. The role of mental health, support and coping on the HIV risk protective and prom
    David Malebranche; Fiscal Year: 2009
    ....
  4. Knee OA: Setting Priorities for Care, Policy, Research
    Elena Losina; Fiscal Year: 2007
    ..This study will provide guidance to clinicians and policy makers on efforts to reduce pain and disability, and to improve quality of life for people with knee osteoarthritis. ..
  5. Modeling Sequential Antiretroviral Therapy in HIV
    Elena Losina; Fiscal Year: 2005
    ..This award will provide critical insight into the optimal strategies for managing HIV infection and will provide Dr. Losina with a solid foundation for development as an independent and productive investigator. ..
  6. Knee OA: Setting Priorities for Care, Policy, Research
    Elena Losina; Fiscal Year: 2010
    ..This study will provide guidance to clinicians and policy makers on efforts to reduce pain and disability, and to improve quality of life for people with knee osteoarthritis. ..
  7. Knee OA: Setting Priorities for Care, Policy, Research
    Elena Losina; Fiscal Year: 2009
    ..This study will provide guidance to clinicians and policy makers on efforts to reduce pain and disability, and to improve quality of life for people with knee osteoarthritis. ..
  8. VISUAL IMPAIRMENT, TREATMENT, AND EFFECTS ON THE ELDERLY
    Frank Sloan; Fiscal Year: 2004
    ..The main database will be the National Long-Term Care Survey (NLTCS) for 1982-2001, merged with Medicare claims data for 1982-2001. Eleven papers are planned. ..
  9. Risk of Adverse Outcomes after Spinal Cord Injury: A Longitudinal Study
    James Krause; Fiscal Year: 2007
    ....
  10. Determinants and Consequences of Alcohol Consumption
    Frank Sloan; Fiscal Year: 2007
    ..abstract_text> ..
  11. Short-term cognitive change in adults from 18 to 80
    Timothy Salthouse; Fiscal Year: 2007
    ....
  12. Lymphoma in Autoimmune Disease: Consequence of Immune Suppression or Stimulation?
    Sasha Bernatsky; Fiscal Year: 2007
    ..Our proposed project will help identify patients at highest risk for lymphoma and provide guidance regarding initiation and maintenance of therapy to control SLE. ..
  13. Visual Impairment, Treatment and Effects on the Elderly
    Frank Sloan; Fiscal Year: 2007
    ..Ten papers are anticipated for this four-year study. ..
  14. Effects of the Minimum Drinking Age on Mortality, Nonfatal Injury, and Crime
    Christopher Carpenter; Fiscal Year: 2007
    ..In so doing, this project will have the potential to reduce alcohol related harms experienced by youths. ..
  15. Effects of Aging on Executive Processes
    Timothy Salthouse; Fiscal Year: 2006
    ..e., specific to individual variables or common to many variables) at which age-related influences operate on executive process variables. ..
  16. A PROSPECTIVE STUDY OF RISK OF MORTALITY AFTER SCI
    James Krause; Fiscal Year: 2002
    ..Risk profiles will be generated to identify individuals at greatest risk for early mortality. Separate analyses and risk profiles will be generated based on injury severity, gender and race/ethnicity. ..
  17. Deterring Drunk Driving: Beliefs, Preferences, Outcomes, and Welfare Implications
    Frank Sloan; Fiscal Year: 2009
    ....
  18. A Measurement Error Approach to Estimating Usual Daily Physical Activity Distribu
    Greg J Welk; Fiscal Year: 2010
    ..Data analyses will involve the development and evaluation of statistical procedures that calibrate the self-report measure against objective physical data to obtain accurate estimates of "usual" physical activity in the population. ..
  19. Risk of Adverse Outcomes after Spinal Cord Injury: A Longitudinal Study
    James S Krause; Fiscal Year: 2010
    ..abstract_text> ..
  20. A Measurement Error Approach to Estimating Usual Daily Physical Activity Distribu
    Greg Welk; Fiscal Year: 2009
    ..Data analyses will involve the development and evaluation of statistical procedures that calibrate the self-report measure against objective physical data to obtain accurate estimates of "usual" physical activity in the population. ..
  21. PRIVATE AND SOCIAL COST OF SMOKING
    Frank Sloan; Fiscal Year: 2001
    ..We will examine implications of our empirical analysis for tort claims brought against tobacco companies and the evolution of legal theories underlying tobacco tort litigation in a law review article. ..
  22. DETERMINANTS AND COST OF ALCOHOL ABUSE AMONG ELDERLY
    Frank Sloan; Fiscal Year: 2001
    ..abstract_text> ..
  23. Deterring Drunk Driving: Beliefs, Preferences, Outcomes, and Welfare Implications
    Frank Sloan; Fiscal Year: 2010
    ....
  24. Visual Impairment, Treatment and Effects on the Elderly
    Frank Sloan; Fiscal Year: 2010
    ..We will document whether appropriate use of recommended care and therapeutic procedures leads to better health outcomes among persons with (1) major eye diseases and (2) diagnosed with diabetes mellitus. ..
  25. Effects of the Minimum Drinking Age on Mortality, Nonfatal Injury, and Crime
    Christopher Carpenter; Fiscal Year: 2009
    ..In so doing, this project will have the potential to reduce alcohol related harms experienced by youths. ..
  26. A Measurement Error Approach to Estimating Usual Daily Physical Activity Distribu
    Greg J Welk; Fiscal Year: 2010
    ..The project is guided by a strong research team with expertise in all necessary facets of the study (physical activity assessment, survey design and administration, and measurement error modeling). ..
  27. Predicting dementia with practice effects
    Kevin Duff; Fiscal Year: 2009
    ..Finally, the availability of a brief, non-invasive, and cost effective marker of disease progression would allow for more efficient and better powered clinical trials. ..
  28. Contribution of TNF-alpha to mucus cell production in asthma
    Paula Busse; Fiscal Year: 2007
    ..The overall goal of this proposal is to evaluate the effects of TNF-a on an important aspect of airway pathology in asthma, mucus-cell hyperplasia/hypertrophy. ..
  29. Study of Women's Health Across the Nation III--UC Davis
    Ellen Gold; Fiscal Year: 2007
    ..We will build upon the rich foundation developed during SWAN I and II and link these data to important menopause-related and health outcomes in SWAN III. ..
  30. Pregnancy Outcomes in Polycystic Ovary Syndrome
    Joan Lo; Fiscal Year: 2009
    ....
  31. Sex Hormones, Related Polymorphisms & Cognitive Decline
    Kristine Yaffe; Fiscal Year: 2006
    ..Further knowledge of the association between sex hormones, hormone-related polymorphisms and cognitive decline may facilitate preventative strategies to maintain independence and to promote optimum brain aging. ..
  32. Lipocalin 2 in Inflammation and Metabolic Control
    Xiaoli Chen; Fiscal Year: 2009
    ..The knowledge obtained will provide the key to solve the molecular puzzle of obesity and lead to the identification of novel strategies for preventive and therapeutic interventions. ..
  33. Study of Woman's Health Across the Nation - UCLA
    Gail Greendale; Fiscal Year: 2007
    ..We will build upon the rich foundation developed during SWAN I and II and link these data to important menopauserelated and health outcomes in SWAN III. ..
  34. Sex Steroids & Mammographic Density in the Postmenopause
    Gail Greendale; Fiscal Year: 2007
    ..We will quantify the relations between the hormone and genetic exposures measured in this project and mammographic density (at baseline as well as change in density between baseline and 12 months). ..
  35. Center for Demography and Ecology
    Alberto Palloni; Fiscal Year: 2007
    ..abstract_text> ..
  36. Drug Abuse Trajectories in the Transition to Adulthood: Risk Factors and Outcomes
    Amelia Arria; Fiscal Year: 2009
    ....
  37. Under the Skin: Understanding the Role of Stress and Immune Function in Health Di
    JENNIFER DOWD; Fiscal Year: 2009
    ..We will test whether these immune and infection markers are related to psychosocial and economic stressors and whether they mediate the relationship between SES and health outcomes including mortality. ..
  38. TREATMENT OF HEPATITIS C WITH AMANTADINE: DOSE ESCALATION STUDY
    Jill Smith; Fiscal Year: 2000
    ..The purpose of this study is to evaluate the efficacy of amantadine in hepatitis C with higher doses of the drug. ..
  39. Systems Biology of Anionic Drug and Metabolite Handling
    Sanjay Nigam; Fiscal Year: 2009
    ..The ultimate goal is to set the stage for a model with predictive power in the clinical contexts of complex metabolic disease phenotypes (eg. hyperuricemia) and pharmacogenomics. ..
  40. ESRD Endocrinopathy and Daily Dialysis
    Joan C Lo; Fiscal Year: 2010
    ..Conventional Hemodialysis. The major goals of this study are to characterize the endocrinopathies associated with ESRD, their change with dialysis frequency, and the relationship of these changes with health-related outcomes. ..
  41. Conditioning-specific reflex modification
    BERNARD SCHREURS; Fiscal Year: 2004
    ..abstract_text> ..
  42. Multivariate Analysis of the Total Fertility Rate and Its Components
    Robert D Retherford; Fiscal Year: 2010
    ..The new methodology involves major extensions of methodology developed during an earlier R03 grant ("Components of Nuptiality and Fertility Change," 5R03HD45508-2, PI: Retherford) that expired November 30, 2007. ..