Genomes and Genes
Summary: Specific practices for the prevention of disease or mental disorders in susceptible individuals or populations. These include HEALTH PROMOTION, including mental health; protective procedures, such as COMMUNICABLE DISEASE CONTROL; and monitoring and regulation of ENVIRONMENTAL POLLUTANTS. Primary prevention is to be distinguished from secondary prevention, which is the prevention of complications or after-effects of a drug or surgical procedure, and tertiary prevention, the amelioration of the after-effects of a disease.
Publications320 found, 100 shown here
- Guidelines for the primary prevention of stroke: a guideline for healthcare professionals from the American Heart Association/American Stroke AssociationLarry B Goldstein
American Heart Association American Stroke Association
Stroke 42:517-84. 2011..This guideline provides an overview of the evidence on established and emerging risk factors for stroke to provide evidence-based recommendations for the reduction of risk of a first stroke...
- Aspirin in the primary and secondary prevention of vascular disease: collaborative meta-analysis of individual participant data from randomised trialsColin Baigent
CTSU, Oxford University, Oxford, UK
Lancet 373:1849-60. 2009Low-dose aspirin is of definite and substantial net benefit for many people who already have occlusive vascular disease. We have assessed the benefits and risks in primary prevention.
- European guidelines on cardiovascular disease prevention in clinical practice: full text. Fourth Joint Task Force of the European Society of Cardiology and other societies on cardiovascular disease prevention in clinical practice (constituted by representIan Graham
Department of Cardiology, The Adelaide and Meath Hospital, Tallaght, Dublin, Ireland
Eur J Cardiovasc Prev Rehabil 14:S1-113. 2007
- Probiotics in primary prevention of atopic disease: a randomised placebo-controlled trialM Kalliomaki
Department of Paediatrics, University of Turku and Turku University Hospital, Finland
Lancet 357:1076-9. 2001..We assessed the effect on atopic disease of Lactobacillus GG (which is safe at an early age and effective in treatment of allergic inflammation and food allergy)...
- Primary prevention of hypertension: clinical and public health advisory from The National High Blood Pressure Education ProgramPaul K Whelton
Department of Epidemiology and Medicine, Tulane University Health Sciences Center, Tulane University, New Orleans, LA, USA
JAMA 288:1882-8. 2002..The National High Blood Pressure Education Program Coordinating Committee published its first statement on the primary prevention of hypertension in 1993...
- Primary prevention of gestational diabetes mellitus and large-for-gestational-age newborns by lifestyle counseling: a cluster-randomized controlled trialRiitta Luoto
UKK Institute for Health Promotion Research, Tampere, Finland
PLoS Med 8:e1001036. 2011..Our objective was to examine whether gestational diabetes mellitus (GDM) or newborns' high birthweight can be prevented by lifestyle counseling in pregnant women at high risk of GDM...
- Measurement of C-reactive protein for the targeting of statin therapy in the primary prevention of acute coronary eventsP M Ridker
Center for Cardiovascular Disease Prevention, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02215, USA
N Engl J Med 344:1959-65. 2001..We hypothesized that statins might prevent coronary events in persons with elevated C-reactive protein levels who did not have overt hyperlipidemia...
- Primary prevention of colorectal cancerAndrew T Chan
Gastrointestinal Unit, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA
Gastroenterology 138:2029-2043.e10. 2010..Taken together, modifications in diet and lifestyle should substantially reduce the risk of colorectal cancer and could complement screening in reducing colorectal cancer incidence...
- Aspirin for primary prevention of cardiovascular events in people with diabetes: meta-analysis of randomised controlled trialsGiorgia De Berardis
Department of Clinical Pharmacology and Epidemiology, Consorzio Mario Negri Sud, Via Nazionale 8 A, 66030 S Maria Imbaro, Italy
BMJ 339:b4531. 2009..To evaluate the benefits and harms of low dose aspirin in people with diabetes and no cardiovascular disease...
- Primary prevention of cardio-metabolic diseases in general practice: a Dutch survey of attitudes and working methods of general practitionersMarkus M J Nielen
NIVEL Netherlands Institute for Health Services Research, Utrecht, The Netherlands
Eur J Gen Pract 16:139-42. 2010To study the attitudes and working methods of general practitioners (GPs) in primary prevention of cardiovascular diseases, diabetes mellitus and chronic kidney diseases.
- Physical activity during leisure time and primary prevention of coronary heart disease: an updated meta-analysis of cohort studiesFrancesco Sofi
Department of Medical and Surgical Critical Care, Thrombosis Centre, Azienda Ospedaliero Universitaria Careggi, University of Florence, Florence, Italy
Eur J Cardiovasc Prev Rehabil 15:247-57. 2008..The real magnitude of the association between physical activity during leisure time (LTPA) and primary prevention of coronary heart disease (CHD) has, however, not been completely defined.
- A pilot study of emollient therapy for the primary prevention of atopic dermatitisEric L Simpson
Department of Dermatology, Oregon Health and Science University, Portland, Oregon 97239 4501, USA
J Am Acad Dermatol 63:587-93. 2010..New research reveals the importance of the skin barrier in the development of AD and possibly food allergy and asthma. Correcting skin barrier defects from birth may prevent AD onset or moderate disease severity...
- The VITamin D and OmegA-3 TriaL (VITAL): rationale and design of a large randomized controlled trial of vitamin D and marine omega-3 fatty acid supplements for the primary prevention of cancer and cardiovascular diseaseJoAnn E Manson
Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, 900 Commonwealth Avenue East, Boston, MA 02215, United States
Contemp Clin Trials 33:159-71. 2012..vitamin D and marine omega-3 fatty acids may reduce risk for cancer or cardiovascular disease (CVD), but primary prevention trials with adequate dosing in general populations (i.e., unselected for disease risk) are lacking...
- Randomized, double-blind, placebo-controlled trial of probiotics for primary prevention: no clinical effects of Lactobacillus GG supplementationMatthias Volkmar Kopp
University Children s Hospital, Mathildenstrasse 1, D 79106 Freiburg, Germany
Pediatrics 121:e850-6. 2008The value of probiotics for primary prevention is controversial. Published trials vary considerably in study design and the applied probiotics, thereby limiting comparability of the results.
- Implementation of the NHS Health Checks programme: baseline assessment of risk factor recording in an urban culturally diverse settingAndrew R H Dalton
Department of Primary Care and Public Health, Imperial College Faculty of Medicine, St Dunstan s Road, London, UK
Fam Pract 28:34-40. 2011..The potential workload implications of the programme for general practice are considerable, particularly in deprived culturally diverse settings...
- Achievement of treatment goals for primary prevention of cardiovascular disease in clinical practice across Europe: the EURIKA studyJose R Banegas
Department of Preventive Medicine and Public Health, School of Medicine, Universidad Autónoma de Madrid IdiPAZ, Avda Arzobispo Morcillo 2, Madrid, Spain
Eur Heart J 32:2143-52. 2011Most studies on the primary prevention of cardiovascular disease (CVD) have been limited to patients at high CVD risk...
- Primary prevention of cardiovascular disease with a Mediterranean dietRamon Estruch
Centro de Investigación Biomédica en Red de Fisiopatología de la Obesidad y Nutrición, Instituto de Salud Carlos III, Madrid, Spain
N Engl J Med 368:1279-90. 2013..We conducted a randomized trial of this diet pattern for the primary prevention of cardiovascular events.
- Rosuvastatin for primary prevention in patients with European systematic coronary risk evaluation risk ≥ 5% or Framingham risk >20%: post hoc analyses of the JUPITER trial requested by European health authoritiesWolfgang Koenig
Department of Internal Medicine II Cardiology, University of Ulm Medical Center, Albert Einstein Allee 23, Ulm, Germany
Eur Heart J 32:75-83. 2011..approved the use of rosuvastatin to reduce first major cardiovascular events among 'high' global risk primary prevention patients defined either by Framingham risk score >20% or European systematic coronary risk evaluation (..
- Optimizing statin treatment for primary prevention of coronary artery diseaseRodney A Hayward
University of Michigan and Veteran Affairs Ann Arbor Healthcare System, Ann Arbor, Michigan, USA
Ann Intern Med 152:69-77. 2010....
- Cost-effectiveness analysis of interventions to prevent cardiovascular disease in VietnamDuc Anh Ha
Ministry of Health, 138A Giangvo, Hanoi, Vietnam
Health Policy Plan 26:210-22. 2011..The burden of CVD will continue to rise unless effective interventions for addressing its underlying risk factors are put in place...
- Excess risk attributable to traditional cardiovascular risk factors in clinical practice settings across Europe - The EURIKA StudyEliseo Guallar
Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA
BMC Public Health 11:704. 2011Physicians involved in primary prevention are key players in CVD risk control strategies, but the expected reduction in CVD risk that would be obtained if all patients attending primary care had their risk factors controlled according to ..
- Cancer prevention in the Asia Pacific regionKeun Young Yoo
Seoul National University College of Medicine, Seoul, Korea
Asian Pac J Cancer Prev 11:839-44. 2010..Moreover, countries with professionals and researchers with advanced cancer research, education, and training also need to contribute through international cooperation...
- Cardiovascular disease prevention with a multidrug regimen in the developing world: a cost-effectiveness analysisThomas A Gaziano
Division of Cardiovascular Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02120, USA
Lancet 368:679-86. 2006..We therefore aimed to establish whether use of evidence-based multidrug regimens for patients at high risk for cardiovascular disease would be cost-effective in low-income and middle-income countries...
- Primary care: is there enough time for prevention?Kimberly S H Yarnall
Department of Community and Family Medicine, Duke University Medical Center, Durham, NC 27710, USA
Am J Public Health 93:635-41. 2003..We sought to determine the amount of time required for a primary care physician to provide recommended preventive services to an average patient panel...
- Diagnosis, prevention, and management of eclampsiaBaha M Sibai
Department of Obstetrics and Gynecology, University of Cincinnati, 231 Albert Sabin Way, Cincinnati, OH 45267, USA
Obstet Gynecol 105:402-10. 2005..Recommendations for diagnosis, prevention, management, and counseling of these women are provided based on results of recent studies and my own clinical experience...
- Challenges and opportunities for cardiovascular disease preventionManuel Franco
Department of Epidemiology, Atherothrombosis and Imaging, National Center for Cardiovascular Research, Madrid, Spain
Am J Med 124:95-102. 2011....
- Rosuvastatin for primary prevention in older persons with elevated C-reactive protein and low to average low-density lipoprotein cholesterol levels: exploratory analysis of a randomized trialRobert J Glynn
Division of Preventive Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02215, USA
Ann Intern Med 152:488-96, W174. 2010Randomized data on statins for primary prevention in older persons are limited, and the relative hazard of cardiovascular disease associated with an elevated cholesterol level weakens with advancing age.
- Primary prevention of cardiovascular diseases with statin therapy: a meta-analysis of randomized controlled trialsPaaladinesh Thavendiranathan
Department of Medicine, University of Toronto, Toronto, Ontario
Arch Intern Med 166:2307-13. 2006..in secondary prevention of cardiovascular (CV) events and mortality is established, their value for primary prevention is less clear...
- Comparing impact and cost-effectiveness of primary prevention strategies for lipid-loweringMark J Pletcher
University of California, San Francisco, San Francisco, California 94107, USA
Ann Intern Med 150:243-54. 2009..Lipid-lowering therapy is costly but effective at reducing coronary heart disease (CHD) risk...
- A randomized trial of low-dose aspirin in the primary prevention of cardiovascular disease in womenPaul M Ridker
Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, USA
N Engl J Med 352:1293-304. 2005..Randomized trials have shown that low-dose aspirin decreases the risk of a first myocardial infarction in men, with little effect on the risk of ischemic stroke. There are few similar data in women...
- A health economic evaluation of aspirin in the primary prevention of cardiovascular disease in JapanKiichiro Tsutani
The Department of Pharmacoeconomics, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan
Intern Med 46:157-62. 2007..But, the use of low-dose aspirin in primary prevention has not yet been fully established in Japan although meta-analyses and US/European guidelines support its ..
- Primary prevention of cardiovascular disease in nursing practice: focus on children and youth: a scientific statement from the American Heart Association Committee on Atherosclerosis, Hypertension, and Obesity in Youth of the Council on Cardiovascular DisLaura L Hayman
New York University, USA
Circulation 116:344-57. 2007
- Carotid intima-media thickness as a screening tool in cardiovascular primary preventionAntonio L Aguilar-Shea
Family Practice, Centro de Salud Espronceda, Área 7 de Madrid, Spain
Eur J Clin Invest 41:521-6. 2011..Increased carotid intima-media thickness (CIMT) is associated with cardiovascular events. The purpose of this study was to identify advanced subclinical atherosclerosis in patients who are at low or intermediate risk...
- Predictors of adherence to statins for primary preventionDevin M Mann
Division of General Internal Medicine, Mount Sinai School of Medicine, 1470 Madison Ave, Box 1087, New York, NY 10029, USA
Cardiovasc Drugs Ther 21:311-6. 2007..This prospective study was designed to identify potentially modifiable patient factors including medication, disease, and diet beliefs related to statin adherence...
- Designing randomized, controlled trials aimed at preventing or delaying functional decline and disability in frail, older persons: a consensus reportLuigi Ferrucci
Clinical Research Branch, National Institute on Aging, National Institutes of Health, Baltimore, Maryland, USA
J Am Geriatr Soc 52:625-34. 2004....
- Aspirin for prevention of cardiovascular events in a general population screened for a low ankle brachial index: a randomized controlled trialF Gerald R Fowkes
Centre for Population Health Sciences, University of Edinburgh, Scotland
JAMA 303:841-8. 2010..Screening for a low ABI can identify an asymptomatic higher risk group potentially amenable to preventive treatments...
- The role of atherosclerosis imaging in redefining normal and abnormal cholesterol values, and risk reduction in primary prevention statin trialsHarvey S Hecht
Lenox Hill Heart and Vascular Institute, 130 E 77th St, New York, NY 10021, USA
Curr Atheroscler Rep 13:422-30. 2011..of cardiovascular events than risk factors of atherosclerosis, has created a paradigm shift in the primary prevention of cardiovascular disease...
- National screening program for transitional ages in Korea: a new screening for strengthening primary prevention and follow-up careHyun Su Kim
Department of Family Medicine, Seoul National University College of Medicine, Seoul, Korea
J Korean Med Sci 27:S70-5. 2012..Lastly, we suggest several points that need to be considered to improve the program such as enhancement of participation rates, necessity of specialized committee and research for current screening program to be supported by evidence...
- The BioImage Study: novel approaches to risk assessment in the primary prevention of atherosclerotic cardiovascular disease--study design and objectivesPieter Muntendam
BG Medicine Inc, Waltham, MA, USA
Am Heart J 160:49-57.e1. 2010..The BioImage Study will help identify those patients with subclinical atherosclerosis who are at risk for near-term atherothrombotic events and enable a more personalized management of care...
- Relation of baseline high-sensitivity C-reactive protein level to cardiovascular outcomes with rosuvastatin in the Justification for Use of statins in Prevention: an Intervention Trial Evaluating Rosuvastatin (JUPITER)Paul M Ridker
Center for Cardiovascular Disease Prevention, Boston, Massachusetts, USA
Am J Cardiol 106:204-9. 2010..Trial Evaluating Rosuvastatin (JUPITER), random allocation of rosuvastatin compared to placebo among primary prevention patients with a low-density lipoprotein cholesterol level of <130 mg/dl and a high-sensitivity C-reactive ..
- Changing the odds. What do we learn from prevention studies targeted at people with a positive family history of type 2 diabetes?Wieke H Heideman
Department of Medical Psychology, The EMGO Institute for Health and Care Research, VU University Medical Centre, Amsterdam, The Netherlands
Prim Care Diabetes 5:215-21. 2011..They can and should be approached with the aim to raise risk awareness and promote healthy eating, weight loss and physical activity, thereby reducing their risk of developing diabetes...
- Contemporary epidemiology of renal cell carcinoma: perspectives of primary preventionSteffen Weikert
Department of Urology, Charite University Medicine Berlin, 10117 Berlin, Germany
World J Urol 28:247-52. 2010..In this review, we give an overview of recent trends in incidence and mortality and summarize the current knowledge on risk factors of RCC...
- Long-term follow-up of primary and secondary prevention implantable cardioverter defibrillator patientsGuido H van Welsenes
Department of Cardiology, Leiden University Medical Center, Leiden, The Netherlands
Europace 13:389-94. 2011..The aim of the study was to assess differences in mortality and ICD therapy between secondary and primary prevention ICD recipients.
- Communicating evidence-based information on cancer prevention to state-level policy makersRoss C Brownson
Alvin J Siteman Cancer Center, Washington University School of Medicine, Washington University, St Louis, MO 63110, USA
J Natl Cancer Inst 103:306-16. 2011..We explored factors that influence the likelihood that state-level policy makers will find a policy brief understandable, credible, and useful...
- Incidence and predictors of implantable cardioverter-defibrillator therapy in patients with arrhythmogenic right ventricular dysplasia/cardiomyopathy undergoing implantable cardioverter-defibrillator implantation for primary preventionAditya Bhonsale
Division of Cardiology, The Johns Hopkins University School of Medicine, Baltimore, MD, USA
J Am Coll Cardiol 58:1485-96. 2011..study was to define the incidence and predictors of implantable cardioverter-defibrillator (ICD) therapy in patients with arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVD/C) after placement of an ICD for primary prevention.
- Primary prevention of stroke: blood pressure, lipids, and heart failureMatthias Endres
Klinik und Hochschulambulanz für Neurologie, Charite Universitatsmedizin Berlin, Berlin, Germany
Eur Heart J 32:545-52. 2011..of stroke, the global burden of this disease can only be tackled with co-ordinated approaches for primary prevention. Stroke is a heterogeneous disease and the contribution of individual risk factors to its occurrence ..
- Lifestyle intervention for preventing weight gain in young adults: a systematic review and meta-analysis of RCTsL Hebden
The University of Sydney, School of Molecular Bioscience, Sydney, New South Wales, Australia
Obes Rev 13:692-710. 2012..Future trials conducted over longer periods with larger samples are urgently required to develop effective programmes that will protect against weight gains in future generations...
- Moving towards a population health approach to the primary prevention of common mental disordersFelice N Jacka
Deakin University, School of Medicine and Barwon Health, PO Box 281, Geelong 3220, Australia
BMC Med 10:149. 2012....
- Identifying individuals for primary cardiovascular disease prevention in UK general practice: priorities and resource implicationsTim A Holt
Health Services Research Institute, Warwick Medical School, Coventry
Br J Gen Pract 58:495-8. 2008..2% of patients aged over 50 years with established cardiovascular disease had at least one modifiable risk factor outside the audit target of the Quality and Outcomes Framework. Implications for resource allocation are discussed...
- A polypill for all? Critical review of the polypill literature for primary prevention of cardiovascular disease and strokeKatherine M Carey
Massachusetts College of Pharmacy and Health Sciences, Worcester, MA, USA
Ann Pharmacother 46:688-95. 2012..the efficacy and safety of the polypill for prevention of cardiovascular disease (CVD) and stroke and to present literature related to the polypill components (statin, aspirin, antihypertensive) for primary prevention of CVD and stroke.
- Risk factors and primary prevention of acute leukemiaGul Ilhan
Department of Hematology, Baskent University Medical School, Ankara, Turkey
Asian Pac J Cancer Prev 7:515-7. 2006..To explain the etiology of all leukemias and develop preventive methods for the disease, future studies are needed...
- Aspirin for primary prevention: yes or no?Vanessa Selak
Clinical Trials Research Unit, School of Population Health, The University of Auckland, Auckland, New Zealand
J Prim Health Care 2:92-9. 2010To assess benefit versus harm of aspirin for cardiovascular disease (CVD) primary prevention by age group, gender and risk category and to interpret these results in light of current New Zealand CVD risk assessment and management ..
- Role of drugs and devices in patients at risk of sudden cardiac deathGiuseppe Boriani
Institute of Cardiology, University of Bologna, Azienda Ospedaliera S Orsola Malpighi, Bologna, Italy Department of Pharmacology, University of Bologna, Bologna, Italy
Fundam Clin Pharmacol 24:575-94. 2010..or a malignant ventricular tachyarrhythmias (secondary prevention of SCD) and the much broader setting of primary prevention in patients at variable degrees of identifiable risk...
- Bridging the gap between public health and primary care in prevention of cardiometabolic diseases; background of and experiences with the Prevention Consultation in The NetherlandsWillem J J Assendelft
Department of Public Health and Primary Care, Leiden University Medical Center, Leiden, The Netherlands
Fam Pract 29:i126-i131. 2012..This initiative was supported by the national professional organizations of GPs and occupational physicians as well as three large health foundations...
- Rationale and methods of the European Study on Cardiovascular Risk Prevention and Management in Daily Practice (EURIKA)Fernando Rodriguez-Artalejo
Department of Preventive Medicine and Public Health, School of Medicine, Universidad Autonoma de Madrid, CIBER of Epidemiology and Public Health, Madrid 28029, Spain
BMC Public Health 10:382. 2010The EURIKA study aims to assess the status of primary prevention of cardiovascular disease (CVD) across Europe...
- Applicability of cholesterol-lowering primary prevention trials to a general population: the framingham heart studyD M Lloyd-Jones
Framingham Heart Study, 5 Thurber St, Framingham, MA 01702, USA
Arch Intern Med 161:949-54. 2001Four large trials have shown cholesterol-reduction therapy to be effective for primary prevention of coronary heart disease (CHD).
- Rosuvastatin for primary prevention among individuals with elevated high-sensitivity c-reactive protein and 5% to 10% and 10% to 20% 10-year risk. Implications of the Justification for Use of Statins in Prevention: an Intervention Trial Evaluating RosuvasPaul M Ridker
Center for Cardiovascular Disease Prevention and Division of Cardiovascular Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02215, USA
Circ Cardiovasc Qual Outcomes 3:447-52. 2010Recent primary prevention guidelines issued in Canada endorse the use of statin therapy among individuals at "intermediate risk" who have elevated levels of high-sensitivity C-reactive protein (hsCRP)...
- Recent advances in the management of chronic stable angina II. Anti-ischemic therapy, options for refractory angina, risk factor reduction, and revascularizationRichard Kones
Cardiometabolic Research Institute, Houston, Texas 77055, USA
Vasc Health Risk Manag 6:749-74. 2010..Optimal medical therapy, percutaneous coronary intervention, and surgery are not competing therapies, but are complementary and form a continuum, each filling an important evidence-based need in modern comprehensive management...
- Influence of general self-efficacy on the effects of a school-based universal primary prevention program of depressive symptoms in adolescents: a randomized and controlled follow-up studyPatrick Pössel
University of Tuebingen at Tuebingen, Germany
J Child Psychol Psychiatry 46:982-94. 2005..Depressive disorders in adolescents are a widespread and increasing problem. Prevention seems a promising and feasible approach...
- Potential use of 10-year and lifetime coronary risk information for preventive cardiology prescribing decisions: a primary care physician surveyStephen D Persell
Northwestern University, Chicago, IL 60611, USA
Arch Intern Med 170:470-7. 2010..Data are sparse regarding how physicians use coronary risk information for prescribing decisions...
- Primary prevention in rheumatology: the importance of hyperuricemiaJanitzia Vazquez-Mellado
Rheumatology Service, Hospital General de Mexico, Faculty of Medicine, Universidad Nacional Autonoma de Mexico, Dr Balmis 148, Col Doctores, 06726 Mexico City, Mexico
Best Pract Res Clin Rheumatol 18:111-24. 2004..Patients with chronic HU and also those with gout require both medical investigation for associated diseases or drugs as well as nutritional counseling and life-style changes. HU should alert physicians to possible complications...
- The NOURISH randomised control trial: positive feeding practices and food preferences in early childhood - a primary prevention program for childhood obesityLynne A Daniels
School of Public Health, Institute of Health and Biomedical Innovation, Queensland University of Technology, Brisbane, Australia
BMC Public Health 9:387. 2009b>Primary prevention of childhood overweight is an international priority. In Australia 20-25% of 2-8 year olds are already overweight...
- Views on primary prevention of cardiovascular disease--an interview study with Swedish GPsLouise Silwer
Nordic School of Public Health, Goteborg, Sweden
BMC Fam Pract 11:44. 2010..general practitioners are now faced with decisions about pharmaceutical or non-pharmaceutical treatment for primary prevention every day...
- Ventricular arrhythmia storms in postinfarction patients with implantable defibrillators for primary prevention indications: a MADIT-II substudyHenry W Sesselberg
Department of Medicine, Cardiology Unit, University of Rochester School of Medicine and Dentistry, Rochester, New York, USA
Heart Rhythm 4:1395-402. 2007..Much of prognostic implications of ventricular arrhythmia storms remain unclear...
- Role of aspirin in the primary prevention of cardiovascular disease in diabetes mellitus: a meta-analysisNaveed Younis
University Hospital South Manchester, Wythenshawe Hospital, Department of Diabetes and Endocrinology, Southmoor Road, Manchester M23 9LT, UK
Expert Opin Pharmacother 11:1459-66. 2010To evaluate the benefits of aspirin in people with diabetes mellitus for the primary prevention of cardiovascular disease.
- Kinesin-like protein 6 (KIF6) polymorphism and the efficacy of rosuvastatin in primary preventionPaul M Ridker
Center for Cardiovascular Disease Prevention and the Division of Cardiovascular Medicine, Brigham and Women s Hospital, Harvard Medical School, 900 Commonwealth Avenue East, Boston, MA 02215, USA
Circ Cardiovasc Genet 4:312-7. 2011..Hypothesis-generating data raise the possibility that carriers of the kinesin-like protein 6 (KIF6) 719 arginine (Arg) allele preferentially benefit from statin therapy, and, on this basis, a commercial assay for KIF6 has been developed...
- Are we losing the battle against cardiometabolic disease? The case for a paradigm shift in primary preventionLutz E Kraushaar
Department of Public Health Medicine, University of Bielefeld, Bielefeld, Germany
BMC Public Health 9:64. 2009..This conflicts with the almost enthusiastic reporting of study results, which demonstrate substantial risk reductions secondary to simple lifestyle changes...
- Benefits of statin therapy and compliance in high risk cardiovascular patientsJoel A Lardizabal
Division of Cardiology, Department of Medicine, University of California in San Francisco Fresno MEP, Fresno, CA, USA
Vasc Health Risk Manag 6:843-53. 2010..To fully reap the benefits of statin therapy, interventions which improve long-term treatment compliance in real-world settings should be encouraged...
- Combined effect of low-risk dietary and lifestyle behaviors in primary prevention of myocardial infarction in womenAgneta Akesson
Division of Nutritional Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Box 210, 17177 Stockholm, Sweden
Arch Intern Med 167:2122-7. 2007..Limited data are available on the benefit of combining healthy dietary and lifestyle behaviors in the prevention of myocardial infarction (MI) in women...
- Microalbuminuria and endothelial dysfunction: emerging targets for primary prevention of end-organ damagePeter Ochodnicky
Department of Clinical Pharmacology, University Medical Center Groningen and Groningen Institute for Drug Exploration GUIDE, University of Groningen, The Netherlands
J Cardiovasc Pharmacol 47:S151-62; discussion S172-6. 2006..current evidence, we propose that microalbuminuria and endothelial dysfunction are an emerging target for primary prevention strategies in cardiovascular disease...
- Efficacy of rosuvastatin among men and women with moderate chronic kidney disease and elevated high-sensitivity C-reactive protein: a secondary analysis from the JUPITER (Justification for the Use of Statins in Prevention-an Intervention Trial Evaluating Paul M Ridker
Center for Cardiovascular Disease Prevention, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02215, USA
J Am Coll Cardiol 55:1266-73. 2010We evaluated the efficacy of statin therapy in primary prevention among individuals with moderate chronic kidney disease (CKD).
- Identifying predictors of high quality care in English general practice: observational studyS M Campbell
National Primary Care Research and Development Centre, University of Manchester, Manchester M13 9PL
BMJ 323:784-7. 2001..To assess variation in the quality of care in general practice and identify factors associated with high quality care...
- Selective estrogen-receptor modulators for primary prevention of breast cancerCarol J Fabian
Department of Internal Medicine, University of Kansas Medical Center, 3901 Rainbow Blvd, Kansas City, KS 66160, USA
J Clin Oncol 23:1644-55. 2005
- Pasos Adelante: the effectiveness of a community-based chronic disease prevention programLisa K Staten
Southwest Center for Community Health Promotion, Mel and Enid Zuckerman Arizona College of Public Health, University of Arizona, Division of Health Promotion Sciences, Tucson, AZ 85719, USA
Prev Chronic Dis 2:A18. 2005Implementing programs that target primary prevention of chronic diseases is critical for at-risk populations...
- Aspirin for the primary prevention of cardiovascular events: an update of the evidence for the U.S. Preventive Services Task ForceTracy Wolff
Agency for Healthcare Research and Quality, Rockville, Maryland 20850, USA
Ann Intern Med 150:405-10. 2009..In 2002, the U.S. Preventive Services Task Force (USPSTF) strongly recommended that clinicians discuss aspirin with adults who are at increased risk for coronary heart disease...
- Primary prevention of type 2 diabetes mellitus by lifestyle intervention: implications for health policyDavid F Williamson
Centers for Disease Control and Prevention, Atlanta, Georgia 30341, USA
Ann Intern Med 140:951-7. 2004..This paper summarizes scientific evidence supporting lifestyle intervention to prevent type 2 diabetes and discusses major policy challenges to broad implementation of lifestyle intervention in the health system...
- A randomized trial of lifestyle intervention in primary healthcare for the modification of cardiovascular risk factorsK Margareta Eriksson
Björknäs Primary Health Care Centre, Boden, Sweden
Scand J Public Health 34:453-61. 2006..To evaluate the effects of a lifestyle intervention programme in primary healthcare, targeted to patients with moderate to high risk of cardiovascular disease in terms of cardiovascular risk factors, physical activity, and quality of life...
- Primary prevention of colorectal cancer: diet and drugsDavid Gatof
Division of Gastroenterology, University of Colorado Health Sciences Center, University of Colorado School of Medicine B158, 4200 E Ninth Avenue, Denver, CO 80262, USA
Gastroenterol Clin North Am 31:587-623, xi. 2002b>Primary prevention of colonic adenomas and cancer through dietary interventions or chemoprevention has great appeal. This article discusses primary prevention goals and promising nutritional or chemopreventive strategies...
- Primary and secondary prevention in the reduction of cancer morbidity and mortalityH O Adami
Department of Medical Epidemiology, Karolinska Institutet, PO Box 281, SE 171 77 Stockholm, Sweden
Eur J Cancer 37:S118-27. 2001..age-adjusted mortality rates from cancer in year 2000 had been reduced by approximately 13% due to primary prevention and an additional 6% due to the combined effect of early diagnosis and screening (secondary prevention)...
- Estimation of the burden of cardiovascular disease attributable to modifiable risk factors and cost-effectiveness analysis of preventative interventions to reduce this burden in ArgentinaAdolfo Rubinstein
Institute for Clinical Effectiveness and Health Policy IECS, Buenos Aires, Argentina
BMC Public Health 10:627. 2010..6% of potential years of life lost (PYLL). The aim of the study was to estimate the burden of acute coronary heart disease (CHD) and stroke and the cost-effectiveness of preventative population-based and clinical interventions...
- Understanding and preventing childhood obesity and related disorders--IDEFICS: a European multilevel epidemiological approachW Ahrens
Division of Epidemiological Methods and Etiologic Research, Bremen Institute for Prevention Research and Social Medicine BIPS, University of Bremen, Linzer Strasse 10, D 28359 Bremen, Germany
Nutr Metab Cardiovasc Dis 16:302-8. 2006..We will propose knowledge-based guidelines on dietary and lifestyle activities for health promotion and disease prevention in children for health professionals, stakeholders and consumers...
- Is it time for a cardiovascular primary prevention trial in the elderly?Jennifer G Robinson
Lipid Research Clinic, Department of Epidemiology, University of Iowa, Iowa City, IA 52242, USA
Stroke 38:441-50. 2007..However, few data are available for primary prevention of cardiovascular disease in those aged > or =70 years.
- Aspirin for primary prevention of cardiovascular events in patients with diabetes: A meta-analysisChunyu Zhang
Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, China
Diabetes Res Clin Pract 87:211-8. 2010To systematically review trials concerning the benefit and risk of aspirin therapy for primary prevention of cardiovascular events in patients with diabetes mellitus.
- History of the concept of 'levels of evidence' and their current status in relation to primary prevention through lifestyle interventionsA Kroke
Institute of Social Medicine, Epidemiology, and Health Economics, Charite, Berlin, Germany
Public Health Nutr 7:279-84. 2004b>Primary prevention is a major option to reduce the burden of chronic disease in populations. Because lifestyle interventions have proved to be effective, lifestyle recommendations including nutritional advice are made abundantly...
- Early markers of allergic disease in a primary prevention study using probiotics: 2.5-year follow-up phaseS L Prescott
School of Paediatrics and Child Health, University of Western Australia, Perth, WA, Australia
Allergy 63:1481-90. 2008..We previously reported that a Lactobacillus acidophilus probiotic strain (LAFTI) L10/LAVRI-A1) given for the first 6 months of life increased the risk of allergen sensitization at 1 year of age...
- Relationship of diabetes-specific knowledge to self-management activities, ambulatory preventive care, and metabolic outcomesStephen D Persell
Division of General Internal Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA
Prev Med 39:746-52. 2004..We sought to determine the relationship of patients' diabetes-specific knowledge with self-management behaviors, use of ambulatory preventive care, and metabolic outcomes...
- Bleeding and stroke risk in a real-world prospective primary prevention cohort of patients with atrial fibrillationDaniela Poli
Department of Heart and Vessels, Thrombosis Centre, Azienda Ospedaliera Universitaria Careggi, Firenze, Italy
Chest 140:918-24. 2011..Therefore, stratifying stroke risk in atrial fibrillation (AF) should perhaps concentrate on primary prevention. However, the risk factors for stroke also lead to an increase in the risk of bleeding...
- Efficacy of primary prevention interventions when fasting and postglucose dysglycemia coexist: analysis of the Indian Diabetes Prevention Programmes (IDPP-1 and IDPP-2)Ambady Ramachandran
India Diabetes Research Foundation and Dr A Ramachandran s Diabetes Hospitals, Chennai, India
Diabetes Care 33:2164-8. 2010..different pathophysiological abnormalities, and their combination may influence the effectiveness of the primary prevention tools...
- Adolescent substance use, parental monitoring, and leisure-time activities: 12-year outcomes of primary prevention in IcelandAlfgeir Logi Kristjansson
Centre for Social Research and Analysis, School of Health and Education, Reykjavik University, Reykjavik, Iceland
Prev Med 51:168-71. 2010..To examine 12-year changes in alcohol use and cigarette smoking in response to community-based prevention activities among Icelandic adolescents...
- Rheumatic fever and rheumatic heart disease: primary prevention is the cost effective optionJames Irlam
Indian J Pediatr 75:86; author reply 86-7. 2008
- Effectiveness of implantable cardioverter-defibrillators for the primary prevention of sudden cardiac death in women with advanced heart failure: a meta-analysis of randomized controlled trialsHamid Ghanbari
Department of Cardiology, Providence Hospital Heart Institute and Medical Center, Southfield, MI 48075, USA
Arch Intern Med 169:1500-6. 2009..Specifically, the role of implantable cardioverter-defibrillators in women with heart failure for the primary prevention of sudden cardiac death has not been well established...
- Primary prevention of cardiovascular diseases by lipid-lowering treatment in German general practice: results from GPs ignoring guidelines and risk calculatorsChristina Oriol-Zerbe
Abteilung Allgemeinmedizin, Universitatsklinikum Dusseldorf, Heinrich Heine University, Dusseldorf, Germany
Eur J Gen Pract 13:27-34. 2007Guidelines/risk calculators for the primary prevention of cardiovascular disease have been developed, which could make decisions for or against therapy easier...
- Collaborating for primary prevention: Rochester's new lead lawKatrina Smith Korfmacher
Environmental Health Sciences Center, University of Rochester Medical Center, Rochester, NY 14642, USA katrina
J Public Health Manag Pract 14:400-6. 2008..Their experience in defining the issue, mustering resources, and structuring their decision-making processes is informative for other communities seeking to overcome barriers to improved primary prevention policy.
- [Primary prevention of bladder cancer. What's new?]J E Altwein
Chirurgische Klinik München Bogenhausen, Denningerstrasse 44, 81679 Munich, Germany
Urologe A 46:616-21. 2007..The study of Cole demonstrating that coffee drinking poses a risk for developing Bc raised interest in primary prevention. In the meantime, however, 42 case-control studies could disprove this finding...
- Patients' acceptance of antihypertensive therapy to prevent cardiovascular disease: a comparison between South Asians and Caucasians in the United KingdomMohsen Aarabi
Academic Unit of Clinical Pharmacology, Division of Clinical Sciences South, The University of Sheffield, Royal Hallamshire Hospital, Sheffield, UK
Eur J Cardiovasc Prev Rehabil 15:59-66. 2008..The aim of this study was to establish local people's willingness to receive antihypertensive treatment for primary prevention of cardiovascular disease (CVD) and to explore the role of ethnicity.
- The challenges of addressing primary prevention of diabetes: a response to recommendations from the chronic disease directors' projectApophia Namageyo-Funa
Division of Diabetes Translation, Centers for Disease Control and Prevention, Atlanta, Georgia 30341, USA
J Public Health Manag Pract 14:26-8. 2008..In particular, they are striving to include primary prevention in their agendas...
- Defining a rational approach to screening for cardiovascular risk in asymptomatic patientsPhilip Greenland
Department of Preventive Medicine, Northwestern University, Feinberg School of Medicine, Chicago, Illinois 60611, USA
J Am Coll Cardiol 52:330-2. 2008..More evidence is needed to justify a policy of screening for CVD...
- [Primary prevention and health promotion--health science fundamentals for health policy]R Rosenbrock
Wissenschaftszentrum Berlin fur Sozialforschung, AG Public Health
Gesundheitswesen 66:146-52. 2004There is a broad health policy consensus about the necessity of augmenting and improving primary prevention. To be successful, the current initiatives need to be supported by concepts, categories and classifications, meeting the criteria ..
- Primary prevention of skin cancer: a review of sun protection in Australia and internationallyWarren R Stanton
School of Health and Rehabilitation Sciences, University of Queensland, St Lucia, Queensland 4072, Australia
Health Promot Int 19:369-78. 2004....
- The primary prevention of rheumatic feverMelissa Kerdemelidis
Community Paediatrics, The University of Auckland, Auckland, New Zealand
J Paediatr Child Health 46:534-48. 2010....
- A Polypill for primary prevention of cardiovascular disease: a feasibility study of the World Health OrganizationElsayed Z Soliman
Division of Public Health Sciences, Wake Forest University School of Medicine, Winston Salem, NC, USA
Trials 12:3. 2011..More information is needed regarding the efficacy in reducing the risk factors of cardiovascular disease (CVD), side effects, improvement in adherence and physician/patient "acceptability" of the Polypill...
- Heart Failure Evaluation in Post-Menopausal Women: The Women's Health InitiativeLiviu Klein; Fiscal Year: 2007..In addition, there are no data examining HRT in primary prevention of CHF among post-menopausal women, or its effects on survival in women who develop CHF...
- A Randomized Efficacy Trial of Moms and Teens for Safe DatesVangie A Foshee; Fiscal Year: 2010..Objectives: The proposed study is to test the efficacy of a selective family-based program for the primary prevention of dating abuse perpetration targeted at adolescents who have been exposed to domestic violence...
- Vitamin D and Omega-3 Fatty Acids(VITAL Trial): Effects on FracturesMERYL SUSAN LEBOFF; Fiscal Year: 2010..Large primary prevention trials with high daily doses of vitamin D and/or omega-3 fatty acids in general populations (i.e...
- Venous thromboembolism among California cancer patientsHelen Chew; Fiscal Year: 2003..that use of anticoagulants, such as warfarin or low molecular weight heparin, may be beneficial in the primary prevention of VTE among cancer patients...
- Vitamin D and Fish Oil for Autoimmune Disease, Inflammation and Joint PainKaren H Costenbader; Fiscal Year: 2010..However, large primary prevention trials with adequate dosing in general populations (i.e...
- PENNSYLVANIA ABUSIVE HEAD TRAUMA PREVENTION PROGRAMMark Dias; Fiscal Year: 2007..1 per 1000 population, this represents approximately 1250 cases annually in the United States. An effective primary prevention strategy that would reduce the incidence of AHT would potentially save the lives of many children and ..
- Effects of Simvastatin on CSF AD biomarkers in cognitively normal subjectsGail Li; Fiscal Year: 2010b>Primary prevention of Alzheimer's disease (AD) promises great clinical and economic benefits but poses great challenges because the pathologic processes of AD start years or even decades prior to clinical symptoms of dementia...
- VITAL-DEP: Depression Endpoint Prevention in the VITamin D and OmegA-3 TriaLOLIVIA IFEOMA OKEREKE; Fiscal Year: 2010..RCT designed to evaluate the efficacy of vitamin D3 and marine omega-3 fatty acid supplements in the primary prevention of cardiovascular disease and cancer among 20,000 older U.S. men and women. We will address two primary aims...
- A Large Randomized Trial of Vitamin D, Omega-3 Fatty Acids and Cognitive DeclineJae H Kang; Fiscal Year: 2010..January 2010) to investigate the effects of vitamin D and marine omega-3 fatty acid supplements on the primary prevention of cardiovascular disease and cancer...
- Primary Prevention of Hypertension in Obese AdolescentsDaniel Feig; Fiscal Year: 2006....
- Intimate Partner Violence Among Low-Income Pregnant Women: Multilevel AnalysisQing Li; Fiscal Year: 2005..IPV in the transition to parenthood warrants special attention on risk assessment and primary prevention from an ecological perspective and an approach directed at the potential perpetrators...
- PSYCHOSOCIAL FACTORS IN SUDDEN CARDIAC DEATHSue Thomas; Fiscal Year: 2002..defibrillators (ICD) on the psychosocial status of heart failure (HF) patients who receive ICD as primary prevention for sudden cardiac death (SCD); and 4) compare the psychosocial impact of ICD with the impact of the other ..
- B VITAMIN ATHEROSCLEROSIS INTERVENTION TRAILHOWARD HODIS; Fiscal Year: 2004DESCRIPTION (adapted from the application): Although primary prevention strategies have focused on key modifiable risk factors for development and progression of atherosclerosis, such as hypercholesterolemia, coronary heart disease (CHD) ..
- Translating an Efficaious HPV Vaccine into the Control of Cervical CancerSharon Bond; Fiscal Year: 2007..2006 of an efficacious human papillomavirus (HPV) vaccine provides an unprecedented opportunity for the primary prevention of cervical cancer...