Research Topics
Genomes and Genes | primary preventionSummarySummary: Specific practices for the prevention of disease or mental disorders in susceptible individuals or populations. These include HEALTH PROMOTION, including mental health; protective procedures, such as COMMUNICABLE DISEASE CONTROL; and monitoring and regulation of ENVIRONMENTAL POLLUTANTS. Primary prevention is to be distinguished from secondary prevention, which is the prevention of complications or after-effects of a drug or surgical procedure, and tertiary prevention, the amelioration of the after-effects of a disease. Top Publications
Research Grants
| Scientific Experts
|
Detail Information
Publications
Identification and management of vascular risk: beyond low density lipoprotein cholesterolJoyce L Ross
Cardiovascular Risk Intervention Program, University of Pennsylvania Health Systems, Philadelphia Heart Institute, Philadelphia, USA
AAOHN J 51:521-31; quiz 532-3. 2003..This group of nurses can play a significant role in forging prevention and stamping out the number one killer of the American population...
Guidelines for the primary prevention of stroke: a guideline for healthcare professionals from the American Heart Association/American Stroke AssociationLarry B Goldstein
American Heart Association American Stroke Association
Stroke 42:517-84. 2011..This guideline provides an overview of the evidence on established and emerging risk factors for stroke to provide evidence-based recommendations for the reduction of risk of a first stroke...
Aspirin in the primary and secondary prevention of vascular disease: collaborative meta-analysis of individual participant data from randomised trialsColin Baigent
CTSU, Oxford University, Oxford, UK
Lancet 373:1849-60. 2009Low-dose aspirin is of definite and substantial net benefit for many people who already have occlusive vascular disease. We have assessed the benefits and risks in primary prevention.- European guidelines on cardiovascular disease prevention in clinical practice: full text. Fourth Joint Task Force of the European Society of Cardiology and other societies on cardiovascular disease prevention in clinical practice (constituted by representIan Graham
Department of Cardiology, The Adelaide and Meath Hospital, Tallaght, Dublin, Ireland
Eur J Cardiovasc Prev Rehabil 14:S1-113. 2007 - Primary prevention of colorectal cancerAndrew T Chan
Gastrointestinal Unit, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA
Gastroenterology 138:2029-2043.e10. 2010..Taken together, modifications in diet and lifestyle should substantially reduce the risk of colorectal cancer and could complement screening in reducing colorectal cancer incidence... - Aspirin for primary prevention of cardiovascular events in people with diabetes: meta-analysis of randomised controlled trialsGiorgia De Berardis
Department of Clinical Pharmacology and Epidemiology, Consorzio Mario Negri Sud, Via Nazionale 8 A, 66030 S Maria Imbaro, Italy
BMJ 339:b4531. 2009..To evaluate the benefits and harms of low dose aspirin in people with diabetes and no cardiovascular disease... - Probiotics in primary prevention of atopic disease: a randomised placebo-controlled trialM Kalliomaki
Department of Paediatrics, University of Turku and Turku University Hospital, Finland
Lancet 357:1076-9. 2001..We assessed the effect on atopic disease of Lactobacillus GG (which is safe at an early age and effective in treatment of allergic inflammation and food allergy)... - Rosuvastatin for primary prevention in patients with European systematic coronary risk evaluation risk ≥ 5% or Framingham risk >20%: post hoc analyses of the JUPITER trial requested by European health authoritiesWolfgang Koenig
Department of Internal Medicine II Cardiology, University of Ulm Medical Center, Albert Einstein Allee 23, Ulm, Germany
Eur Heart J 32:75-83. 2011..approved the use of rosuvastatin to reduce first major cardiovascular events among 'high' global risk primary prevention patients defined either by Framingham risk score >20% or European systematic coronary risk evaluation (SCORE).. - Primary prevention of gestational diabetes mellitus and large-for-gestational-age newborns by lifestyle counseling: a cluster-randomized controlled trialRiitta Luoto
UKK Institute for Health Promotion Research, Tampere, Finland
PLoS Med 8:e1001036. 2011..Our objective was to examine whether gestational diabetes mellitus (GDM) or newborns' high birthweight can be prevented by lifestyle counseling in pregnant women at high risk of GDM... - Optimizing statin treatment for primary prevention of coronary artery diseaseRodney A Hayward
University of Michigan and Veteran Affairs Ann Arbor Healthcare System, Ann Arbor, Michigan, USA
Ann Intern Med 152:69-77. 2010.... - Physical activity during leisure time and primary prevention of coronary heart disease: an updated meta-analysis of cohort studiesFrancesco Sofi
Department of Medical and Surgical Critical Care, Thrombosis Centre, Azienda Ospedaliero Universitaria Careggi, University of Florence, Florence, Italy
Eur J Cardiovasc Prev Rehabil 15:247-57. 2008..The real magnitude of the association between physical activity during leisure time (LTPA) and primary prevention of coronary heart disease (CHD) has, however, not been completely defined. - Aspirin for prevention of cardiovascular events in a general population screened for a low ankle brachial index: a randomized controlled trialF Gerald R Fowkes
Centre for Population Health Sciences, University of Edinburgh, Scotland
JAMA 303:841-8. 2010..Screening for a low ABI can identify an asymptomatic higher risk group potentially amenable to preventive treatments... - Rosuvastatin for primary prevention in older persons with elevated C-reactive protein and low to average low-density lipoprotein cholesterol levels: exploratory analysis of a randomized trialRobert J Glynn
Division of Preventive Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02215, USA
Ann Intern Med 152:488-96, W174. 2010Randomized data on statins for primary prevention in older persons are limited, and the relative hazard of cardiovascular disease associated with an elevated cholesterol level weakens with advancing age. - Cancer prevention in the Asia Pacific regionKeun Young Yoo
Seoul National University College of Medicine, Seoul, Korea
Asian Pac J Cancer Prev 11:839-44. 2010..Moreover, countries with professionals and researchers with advanced cancer research, education, and training also need to contribute through international cooperation... - Primary prevention of cardiovascular disease in nursing practice: focus on children and youth: a scientific statement from the American Heart Association Committee on Atherosclerosis, Hypertension, and Obesity in Youth of the Council on Cardiovascular DisLaura L Hayman
New York University, USA
Circulation 116:344-57. 2007 - Primary prevention of cardiovascular diseases with statin therapy: a meta-analysis of randomized controlled trialsPaaladinesh Thavendiranathan
Department of Medicine, University of Toronto, Toronto, Ontario
Arch Intern Med 166:2307-13. 2006..in secondary prevention of cardiovascular (CV) events and mortality is established, their value for primary prevention is less clear... - Comparing impact and cost-effectiveness of primary prevention strategies for lipid-loweringMark J Pletcher
University of California, San Francisco, San Francisco, California 94107, USA
Ann Intern Med 150:243-54. 2009..Lipid-lowering therapy is costly but effective at reducing coronary heart disease (CHD) risk... - A randomized trial of low-dose aspirin in the primary prevention of cardiovascular disease in womenPaul M Ridker
Division of Preventive Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, USA
N Engl J Med 352:1293-304. 2005.... - Rationale and methods of the European Study on Cardiovascular Risk Prevention and Management in Daily Practice (EURIKA)Fernando Rodriguez-Artalejo
Department of Preventive Medicine and Public Health, School of Medicine, Universidad Autonoma de Madrid, CIBER of Epidemiology and Public Health, Madrid 28029, Spain
BMC Public Health 10:382. 2010The EURIKA study aims to assess the status of primary prevention of cardiovascular disease (CVD) across Europe... - Rosuvastatin for primary prevention among individuals with elevated high-sensitivity c-reactive protein and 5% to 10% and 10% to 20% 10-year risk. Implications of the Justification for Use of Statins in Prevention: an Intervention Trial Evaluating RosuvasPaul M Ridker
Center for Cardiovascular Disease Prevention and Division of Cardiovascular Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02215, USA
Circ Cardiovasc Qual Outcomes 3:447-52. 2010Recent primary prevention guidelines issued in Canada endorse the use of statin therapy among individuals at "intermediate risk" who have elevated levels of high-sensitivity C-reactive protein (hsCRP)... - Implementation of the NHS Health Checks programme: baseline assessment of risk factor recording in an urban culturally diverse settingAndrew R H Dalton
Department of Primary Care and Public Health, Imperial College Faculty of Medicine, St Dunstan s Road, London, UK
Fam Pract 28:34-40. 2011..The potential workload implications of the programme for general practice are considerable, particularly in deprived culturally diverse settings... - Primary prevention in rheumatology: the importance of hyperuricemiaJanitzia Vazquez-Mellado
Rheumatology Service, Hospital General de Mexico, Faculty of Medicine, Universidad Nacional Autonoma de Mexico, Dr Balmis 148, Col Doctores, 06726 Mexico City, Mexico
Best Pract Res Clin Rheumatol 18:111-24. 2004..Patients with chronic HU and also those with gout require both medical investigation for associated diseases or drugs as well as nutritional counseling and life-style changes. HU should alert physicians to possible complications... - Cardiovascular disease prevention with a multidrug regimen in the developing world: a cost-effectiveness analysisThomas A Gaziano
Division of Cardiovascular Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02120, USA
Lancet 368:679-86. 2006..We therefore aimed to establish whether use of evidence-based multidrug regimens for patients at high risk for cardiovascular disease would be cost-effective in low-income and middle-income countries... - Recent advances in the management of chronic stable angina II. Anti-ischemic therapy, options for refractory angina, risk factor reduction, and revascularizationRichard Kones
Cardiometabolic Research Institute, Houston, Texas 77055, USA
Vasc Health Risk Manag 6:749-74. 2010..Optimal medical therapy, percutaneous coronary intervention, and surgery are not competing therapies, but are complementary and form a continuum, each filling an important evidence-based need in modern comprehensive management... - A pilot study of emollient therapy for the primary prevention of atopic dermatitisEric L Simpson
Department of Dermatology, Oregon Health and Science University, Portland, Oregon 97239 4501, USA
J Am Acad Dermatol 63:587-93. 2010..New research reveals the importance of the skin barrier in the development of AD and possibly food allergy and asthma. Correcting skin barrier defects from birth may prevent AD onset or moderate disease severity... - Potential use of 10-year and lifetime coronary risk information for preventive cardiology prescribing decisions: a primary care physician surveyStephen D Persell
Northwestern University, Chicago, IL 60611, USA
Arch Intern Med 170:470-7. 2010..Data are sparse regarding how physicians use coronary risk information for prescribing decisions... - Influence of general self-efficacy on the effects of a school-based universal primary prevention program of depressive symptoms in adolescents: a randomized and controlled follow-up studyPatrick Pössel
University of Tuebingen at Tuebingen, Germany
J Child Psychol Psychiatry 46:982-94. 2005..Depressive disorders in adolescents are a widespread and increasing problem. Prevention seems a promising and feasible approach... - The NOURISH randomised control trial: positive feeding practices and food preferences in early childhood - a primary prevention program for childhood obesityLynne A Daniels
School of Public Health, Institute of Health and Biomedical Innovation, Queensland University of Technology, Brisbane, Australia
BMC Public Health 9:387. 2009b>Primary prevention of childhood overweight is an international priority. In Australia 20-25% of 2-8 year olds are already overweight... - Applicability of cholesterol-lowering primary prevention trials to a general population: the framingham heart studyD M Lloyd-Jones
Framingham Heart Study, 5 Thurber St, Framingham, MA 01702, USA
Arch Intern Med 161:949-54. 2001Four large trials have shown cholesterol-reduction therapy to be effective for primary prevention of coronary heart disease (CHD). - Efficacy of rosuvastatin among men and women with moderate chronic kidney disease and elevated high-sensitivity C-reactive protein: a secondary analysis from the JUPITER (Justification for the Use of Statins in Prevention-an Intervention Trial Evaluating Paul M Ridker
Center for Cardiovascular Disease Prevention, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02215, USA
J Am Coll Cardiol 55:1266-73. 2010We evaluated the efficacy of statin therapy in primary prevention among individuals with moderate chronic kidney disease (CKD). - Benefits of statin therapy and compliance in high risk cardiovascular patientsJoel A Lardizabal
Division of Cardiology, Department of Medicine, University of California in San Francisco Fresno MEP, Fresno, CA, USA
Vasc Health Risk Manag 6:843-53. 2010..To fully reap the benefits of statin therapy, interventions which improve long-term treatment compliance in real-world settings should be encouraged... - Microalbuminuria and endothelial dysfunction: emerging targets for primary prevention of end-organ damagePeter Ochodnicky
Department of Clinical Pharmacology, University Medical Center Groningen and Groningen Institute for Drug Exploration GUIDE, University of Groningen, The Netherlands
J Cardiovasc Pharmacol 47:S151-62; discussion S172-6. 2006..current evidence, we propose that microalbuminuria and endothelial dysfunction are an emerging target for primary prevention strategies in cardiovascular disease... - Role of aspirin in the primary prevention of cardiovascular disease in diabetes mellitus: a meta-analysisNaveed Younis
University Hospital South Manchester, Wythenshawe Hospital, Department of Diabetes and Endocrinology, Southmoor Road, Manchester M23 9LT, UK
Expert Opin Pharmacother 11:1459-66. 2010To evaluate the benefits of aspirin in people with diabetes mellitus for the primary prevention of cardiovascular disease. - Views on primary prevention of cardiovascular disease--an interview study with Swedish GPsLouise Silwer
Nordic School of Public Health, Goteborg, Sweden
BMC Fam Pract 11:44. 2010..general practitioners are now faced with decisions about pharmaceutical or non-pharmaceutical treatment for primary prevention every day... - Combined effect of low-risk dietary and lifestyle behaviors in primary prevention of myocardial infarction in womenAgneta Akesson
Division of Nutritional Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Box 210, 17177 Stockholm, Sweden
Arch Intern Med 167:2122-7. 2007..Limited data are available on the benefit of combining healthy dietary and lifestyle behaviors in the prevention of myocardial infarction (MI) in women... - Ventricular arrhythmia storms in postinfarction patients with implantable defibrillators for primary prevention indications: a MADIT-II substudyHenry W Sesselberg
Department of Medicine, Cardiology Unit, University of Rochester School of Medicine and Dentistry, Rochester, New York, USA
Heart Rhythm 4:1395-402. 2007..Much of prognostic implications of ventricular arrhythmia storms remain unclear... - Kinesin-like protein 6 (KIF6) polymorphism and the efficacy of rosuvastatin in primary preventionPaul M Ridker
Center for Cardiovascular Disease Prevention and the Division of Cardiovascular Medicine, Brigham and Women s Hospital, Harvard Medical School, 900 Commonwealth Avenue East, Boston, MA 02215, USA
Circ Cardiovasc Genet 4:312-7. 2011..Hypothesis-generating data raise the possibility that carriers of the kinesin-like protein 6 (KIF6) 719 arginine (Arg) allele preferentially benefit from statin therapy, and, on this basis, a commercial assay for KIF6 has been developed... - Are we losing the battle against cardiometabolic disease? The case for a paradigm shift in primary preventionLutz E Kraushaar
Department of Public Health Medicine, University of Bielefeld, Bielefeld, Germany
BMC Public Health 9:64. 2009..This conflicts with the almost enthusiastic reporting of study results, which demonstrate substantial risk reductions secondary to simple lifestyle changes... - Aspirin for the primary prevention of cardiovascular events: an update of the evidence for the U.S. Preventive Services Task ForceTracy Wolff
Agency for Healthcare Research and Quality, Rockville, Maryland 20850, USA
Ann Intern Med 150:405-10. 2009..In 2002, the U.S. Preventive Services Task Force (USPSTF) strongly recommended that clinicians discuss aspirin with adults who are at increased risk for coronary heart disease... - Primary prevention of type 2 diabetes mellitus by lifestyle intervention: implications for health policyDavid F Williamson
Centers for Disease Control and Prevention, Atlanta, Georgia 30341, USA
Ann Intern Med 140:951-7. 2004..This paper summarizes scientific evidence supporting lifestyle intervention to prevent type 2 diabetes and discusses major policy challenges to broad implementation of lifestyle intervention in the health system... - A randomized trial of lifestyle intervention in primary healthcare for the modification of cardiovascular risk factorsK Margareta Eriksson
Björknäs Primary Health Care Centre, Boden, Sweden
Scand J Public Health 34:453-61. 2006..To evaluate the effects of a lifestyle intervention programme in primary healthcare, targeted to patients with moderate to high risk of cardiovascular disease in terms of cardiovascular risk factors, physical activity, and quality of life... - Primary prevention of colorectal cancer: diet and drugsDavid Gatof
Division of Gastroenterology, University of Colorado Health Sciences Center, University of Colorado School of Medicine B158, 4200 E. Ninth Avenue, Denver, CO 80262, USA
Gastroenterol Clin North Am 31:587-623, xi. 2002b>Primary prevention of colonic adenomas and cancer through dietary interventions or chemoprevention has great appeal. This article discusses primary prevention goals and promising nutritional or chemopreventive strategies... - Relation of baseline high-sensitivity C-reactive protein level to cardiovascular outcomes with rosuvastatin in the Justification for Use of statins in Prevention: an Intervention Trial Evaluating Rosuvastatin (JUPITER)Paul M Ridker
Center for Cardiovascular Disease Prevention, Boston, Massachusetts, USA
Am J Cardiol 106:204-9. 2010..Trial Evaluating Rosuvastatin (JUPITER), random allocation of rosuvastatin compared to placebo among primary prevention patients with a low-density lipoprotein cholesterol level of <130 mg/dl and a high-sensitivity C-reactive .. - Is it time for a cardiovascular primary prevention trial in the elderly?Jennifer G Robinson
Lipid Research Clinic, Department of Epidemiology, University of Iowa, Iowa City, IA 52242, USA
Stroke 38:441-50. 2007..However, few data are available for primary prevention of cardiovascular disease in those aged > or =70 years. - Aspirin for primary prevention of cardiovascular events in patients with diabetes: A meta-analysisChunyu Zhang
Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, China
Diabetes Res Clin Pract 87:211-8. 2010To systematically review trials concerning the benefit and risk of aspirin therapy for primary prevention of cardiovascular events in patients with diabetes mellitus. - History of the concept of 'levels of evidence' and their current status in relation to primary prevention through lifestyle interventionsA Kroke
Institute of Social Medicine, Epidemiology, and Health Economics, Charite, Berlin, Germany
Public Health Nutr 7:279-84. 2004b>Primary prevention is a major option to reduce the burden of chronic disease in populations. Because lifestyle interventions have proved to be effective, lifestyle recommendations including nutritional advice are made abundantly... - Primary prevention of hypertension: clinical and public health advisory from The National High Blood Pressure Education ProgramPaul K Whelton
Department of Epidemiology and Medicine, Tulane University Health Sciences Center, Tulane University, New Orleans, LA, USA
JAMA 288:1882-8. 2002..The National High Blood Pressure Education Program Coordinating Committee published its first statement on the primary prevention of hypertension in 1993... - Measurement of C-reactive protein for the targeting of statin therapy in the primary prevention of acute coronary eventsP M Ridker
Center for Cardiovascular Disease Prevention, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02215, USA
N Engl J Med 344:1959-65. 2001..We hypothesized that statins might prevent coronary events in persons with elevated C-reactive protein levels who did not have overt hyperlipidemia... - Relationship of diabetes-specific knowledge to self-management activities, ambulatory preventive care, and metabolic outcomesStephen D Persell
Division of General Internal Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA
Prev Med 39:746-52. 2004..Providing patient education about diabetes care processes should be tested as a means of increasing ambulatory care to prevent diabetes complications... - Early markers of allergic disease in a primary prevention study using probiotics: 2.5-year follow-up phaseS L Prescott
School of Paediatrics and Child Health, University of Western Australia, Perth, WA, Australia
Allergy 63:1481-90. 2008..We previously reported that a Lactobacillus acidophilus probiotic strain (LAFTI) L10/LAVRI-A1) given for the first 6 months of life increased the risk of allergen sensitization at 1 year of age... - [Primary prevention and health promotion--health science fundamentals for health policy]R Rosenbrock
Wissenschaftszentrum Berlin fur Sozialforschung, AG Public Health
Gesundheitswesen 66:146-52. 2004There is a broad health policy consensus about the necessity of augmenting and improving primary prevention. To be successful, the current initiatives need to be supported by concepts, categories and classifications, meeting the criteria .. - Primary prevention of skin cancer: a review of sun protection in Australia and internationallyWarren R Stanton
School of Health and Rehabilitation Sciences, University of Queensland, St Lucia, Queensland 4072, Australia
Health Promot Int 19:369-78. 2004.... - Defining a rational approach to screening for cardiovascular risk in asymptomatic patientsPhilip Greenland
Department of Preventive Medicine, Northwestern University, Feinberg School of Medicine, Chicago, Illinois 60611, USA
J Am Coll Cardiol 52:330-2. 2008..More evidence is needed to justify a policy of screening for CVD... - Collaborating for primary prevention: Rochester's new lead lawKatrina Smith Korfmacher
Environmental Health Sciences Center, University of Rochester Medical Center, Rochester, NY 14642, USA katrina
J Public Health Manag Pract 14:400-6. 2008..Their experience in defining the issue, mustering resources, and structuring their decision-making processes is informative for other communities seeking to overcome barriers to improved primary prevention policy. - The primary prevention of rheumatic feverMelissa Kerdemelidis
Community Paediatrics, The University of Auckland, Auckland, New Zealand
J Paediatr Child Health 46:534-48. 2010.... - The challenges of addressing primary prevention of diabetes: a response to recommendations from the chronic disease directors' projectApophia Namageyo-Funa
Division of Diabetes Translation, Centers for Disease Control and Prevention, Atlanta, Georgia 30341, USA
J Public Health Manag Pract 14:26-8. 2008..In particular, they are striving to include primary prevention in their agendas... - Patients' acceptance of antihypertensive therapy to prevent cardiovascular disease: a comparison between South Asians and Caucasians in the United KingdomMohsen Aarabi
Academic Unit of Clinical Pharmacology, Division of Clinical Sciences South, The University of Sheffield, Royal Hallamshire Hospital, Sheffield, UK
Eur J Cardiovasc Prev Rehabil 15:59-66. 2008..The aim of this study was to establish local people's willingness to receive antihypertensive treatment for primary prevention of cardiovascular disease (CVD) and to explore the role of ethnicity. - [Primary prevention of bladder cancer. What's new?]J E Altwein
Chirurgische Klinik München Bogenhausen, Denningerstrasse 44, 81679 Munich, Germany
Urologe A 46:616-21. 2007..The study of Cole demonstrating that coffee drinking poses a risk for developing Bc raised interest in primary prevention. In the meantime, however, 42 case-control studies could disprove this finding... - Cost effectiveness of implantable cardioverter-defibrillators for primary prevention in a Belgian contextMattias Neyt
Belgian Health Care Knowledge Centre, Administratief Centrum Kruidtuin, Brussels, Belgium
Appl Health Econ Health Policy 6:67-80. 2008..Its use in primary prevention (i.e... - A pilot study for the primary prevention of rheumatic fever in Kosrae, Federated States of MicronesiaL A Kohler
Department of Health and Social Affairs, P O Box PS 70, Palikir, Pohnpei, Federated States of Micronesia, FM 96941
Pac Health Dialog 16:99-108. 2010..In this preliminary study the feasibility of a rheumatic heart disease primary prevention strategy was examined... - Aspirin for primary prevention: do potential benefits outweigh the risks?S Shakib
Department of Clinical Pharmacology, Royal Adelaide Hospital, Adelaide, South Australia, Australia
Intern Med J 39:401-7. 2009The role of aspirin for primary prevention in healthy individuals has been the subject of clinical trials for more than a quarter of a century... - The prevention of cardiovascular disease: have we really made progress?Thomas A Pearson
Department of Community and Preventive Medicine, University of Rochester School of Medicine and Dentistry, New York, USA
Health Aff (Millwood) 26:49-60. 2007..To improve compliance with secondary prevention guidelines, programs must better organize and monitor care. Primary prevention requires assessment of risk in asymptomatic people, to yield cost-effective benefits... - [Primary prevention and treatment of latent tuberculosis infection with isoniazid: efficacy of a control program, 1997-2002]A Martinez Sanchis
Seccion de Neumologia, Hospital Marina Baixa, Villajoyosa, Alicante, Spain
Arch Bronconeumol 41:27-33. 2005..To analyze the efficacy of a specific program for the study and follow up of tuberculosis contacts. To study factors related to low adherence to treatment and to the development of liver toxicity caused by isoniazid... - Folate intake and the primary prevention of non-neural birth defectsCarol Bower
Telethon Institute for Child Health Research, Centre for Child Health Research, University of Western Australia, West Perth
Aust N Z J Public Health 30:258-61. 2006..To investigate whether maternal periconceptional folate intake is associated with a reduction in selected non-neural birth defects in Western Australia (WA)... - Do lipids and apolipoproteins predict coronary heart disease under statin and fibrate therapy in the primary prevention setting in community-dwelling elderly subjects? The 3C StudyC Straczek
INSERM U970, Paris Cardiovascular Research Center, Paris Descartes University, UMR S970, Paris, France
Atherosclerosis 214:426-31. 2011To evaluate associations of standard lipids and apolipoproteins with incident coronary heart disease (CHD) in older adults according to lipid-lowering treatment (LLT) in the primary prevention setting. - Rosuvastatin, inflammation, C-reactive protein, JUPITER, and primary prevention of cardiovascular disease--a perspectiveRichard Kones
The Cardiometabolic Research, Institute, Houston, TX 77054, USA
Drug Des Devel Ther 4:383-413. 2010..high risk burdens, JUPITER simply offers another choice for stratification and earlier risk reduction in primary prevention patients... - Effect of lovastatin on primary prevention of cardiovascular events in mild CKD and kidney function loss: a post hoc analysis of the Air Force/Texas Coronary Atherosclerosis Prevention StudyJessica Kendrick
Division of Renal Diseases and Hypertension, University of Colorado Denver Health Sciences Center, Aurora, CO 80220, USA
Am J Kidney Dis 55:42-9. 2010..with an increased risk of incident cardiovascular disease (CVD); however, the role of statins for the primary prevention of acute cardiovascular events in patients with CKD and the effect of statins on kidney function loss in .. - Rethinking well-child careEdward L Schor
Commonwealth Fund, New York, New York 10021-2692, USA
Pediatrics 114:210-6. 2004 - The struggle for primary prevention of skin cancerMartin A Weinstock
Am J Prev Med 34:171-2. 2008 - Novel pathogenic insights in the primary prevention of cardiovascular diseaseClaudio Napoli
Department of General Pathology, Clinical Pathology and Excellence Research Center on Cardiovascular Diseases, 1st School of Medicine, II University of Naples, Complesso S Andrea delle Dame Via Costantinopoli 16, Naples, Italy
Prog Cardiovasc Dis 51:503-23. 2009..We provide a coherent path depicting the natural evolution of primary prevention paradigm from in utero fetal development to elderly, in which all preventive strategies to reduce CVD are .. - Group motivational intervention in overweight/obese patients in primary prevention of cardiovascular disease in the primary healthcare areaJuan José Rodríguez Cristóbal
Medicina, Area Básica Salud Florida Sud, Parc dels Ocellets, L Hospitalet del Llobregat, Barcelona, Spain
BMC Fam Pract 11:23. 2010.... - Challenges and opportunities for cardiovascular disease preventionManuel Franco
Department of Epidemiology, Atherothrombosis and Imaging, National Center for Cardiovascular Research, Madrid, Spain
Am J Med 124:95-102. 2011.... - Primary prevention protects public healthLorenzo Tomatis
Cave 25 r, 34011 Aurisina Trieste, Italy
Ann N Y Acad Sci 982:190-7. 2002..approach to carcinogenicity can ascertain and predict potential cancer risks to humans in time for primary prevention to be successful... - The BioImage Study: novel approaches to risk assessment in the primary prevention of atherosclerotic cardiovascular disease--study design and objectivesPieter Muntendam
BG Medicine Inc, Waltham, MA, USA
Am Heart J 160:49-57.e1. 2010..The BioImage Study will help identify those patients with subclinical atherosclerosis who are at risk for near-term atherothrombotic events and enable a more personalized management of care... - Primary prevention for patients with intermediate Framingham risk scoresJason B Thompson
Curr Cardiol Rep 8:261-6. 2006..of the health and economic consequences of CHD, there is a need to develop better prognostic tools for primary prevention. Coronary artery calcium scoring, C-reactive protein measurement, and heart rate recovery and exercise .. - Overcoming barriers to engaging socio-economically disadvantaged populations in CHD primary prevention: a qualitative studyChristopher Harkins
Department of Cardiology, Royal Alexandra Hospital, Paisley PA29PN, UK
BMC Public Health 10:391. 2010..This paper explores the barriers and facilitators to engaging a socio-economically disadvantaged (SED) population in primary prevention for coronary heart disease (CHD). - A new approach to primary prevention of cardiovascular diseaseJohn B Kostis
UMDNJ-Robert Wood Johnson Medical School, Division of Cardiology, New Brunswick, NJ, USA
Am J Med 120:746-7. 2007 - Role of experimental and epidemiological evidence of carcinogenicity in the primary prevention of cancerLorenzo Tomatis
International Society of Doctors for the Environment, Aurisina, Trieste, Italy
Ann Ist Super Sanita 42:113-7. 2006..on Cancer (IARC) did initiate a programme for identifying the cause of cancer with the aim of promoting the primary prevention of cancer... - The primary prevention of heart disease in women through health behavior change promotion in primary careEvelyn P Whitlock
Health, Social Sciences, and Economics Research, Kaiser Permanente Center for Health Research, Portland, Oregon 97227, USA
Womens Health Issues 13:122-41. 2003..S. Preventive Services Task Force (USPSTF) and the Task Force on Community Preventive Services (CTF), and examine their applicability to the primary prevention of cardiovascular disease (CVD) in women through primary care interventions. - A Polypill for primary prevention of cardiovascular disease: a feasibility study of the World Health OrganizationElsayed Z Soliman
Division of Public Health Sciences, Wake Forest University School of Medicine, Winston Salem, NC, USA
Trials 12:3. 2011..More information is needed regarding the efficacy in reducing the risk factors of cardiovascular disease (CVD), side effects, improvement in adherence and physician/patient "acceptability" of the Polypill... - Statins for primary prevention of cardiovascular mortality in women: a systematic review and meta-analysisRadhika N Bukkapatnam
Division of Cardiovascular Medicine, University of California, Davis Medical Center, Sacramento, CA, USA
Prev Cardiol 13:84-90. 2010..The authors systematically reviewed all the published literature on primary prevention trials and found 6 primary prevention trials to date with sex-specific data on mortality and coronary heart .. - Contemporary epidemiology of renal cell carcinoma: perspectives of primary preventionSteffen Weikert
Department of Urology, Charite University Medicine Berlin, 10117 Berlin, Germany
World J Urol 28:247-52. 2010..In this review, we give an overview of recent trends in incidence and mortality and summarize the current knowledge on risk factors of RCC... - Aspirin for the primary prevention of cardiovascular events: a systematic review and meta-analysis comparing patients with and without diabetesAndrew D Calvin
Mayo School of Graduate Medical Education, Mayo Clinic, Rochester, Minnesota, USA
Diabetes Care 32:2300-6. 2009..randomized controlled trials (RCTs) have challenged current guideline recommendations for using aspirin for primary prevention of cardiovascular events among patients with diabetes... - Regional and practice variation in adherence to guideline recommendations for secondary and primary prevention among outpatients with atherothrombosis or risk factors in the United States: a report from the REACH RegistryAmit Kumar
Department of Hospital Medicine, University of Massachusetts Medical School, Worcester, MA, USA
Crit Pathw Cardiol 8:104-11. 2009..Few data are available for outpatients in actual clinical practice, especially those without known heart disease treated by physicians trained in different specialties across the geographic regions of the United States... - The development of a simulation model of primary prevention strategies for coronary heart diseaseHannah Babad
Health Care Manag Sci 5:269-74. 2002..is intended to support health policy makers in assessing the impacts on health care resources of different primary prevention strategies... - The ABCs of hepatitisThad R Wilson
University of Missouri-Kansas City School of Nursing, Kansas City, MO, USA
Nurse Pract 30:12-21, quiz 22-3. 2005 - Type 2 diabetes in children: a growing epidemicTammy F Jones
Eastern Kentucky University, USA
Ky Nurse 55:7-8. 2007 - Implications of LDL subclass B in patients at cardiovascular riskCheryl Moredich
School of Nursing, Purdue University Calumet, Hammond, Ind, USA
Nurse Pract 30:16-8, 23, 26, passim; quiz 29-31. 2005 - European guidelines on cardiovascular disease prevention in clinical practice: executive summary. Fourth Joint Task Force of the European Society of Cardiology and other societies on cardiovascular disease prevention in clinical practice (constituted by rIan Graham
Department of Cardiology, The Adelaide and Meath Hospital, Tallaght, Doublin, Ireland
Eur J Cardiovasc Prev Rehabil 14:E1-40. 2007 - Physical activity monitoring in children and youthsKristie F Bjornson
School of Nursing, Department of Rehabilitation Medicine, School of Medicine, University of Washington, Seattle, WA, USA
Pediatr Phys Ther 17:37-45. 2005..Finally, examples of pediatric physical activity monitoring are presented in the context of clinical practice and research... - Clinical implications of C-reactive protein as a predictor of vascular riskCarolyn Katrinchak
J Am Acad Nurse Pract 19:335-40. 2007..To describe the role of C-reactive protein (CRP) as a marker of risk for coronary heart disease (CHD) and its role in risk reduction and disease prevention for the primary care provider... - Primary prevention of cardiovascular diseases by lipid-lowering treatment in German general practice: results from GPs ignoring guidelines and risk calculatorsChristina Oriol-Zerbe
Abteilung Allgemeinmedizin, Universitatsklinikum Dusseldorf, Heinrich Heine University, Dusseldorf, Germany
Eur J Gen Pract 13:27-34. 2007Guidelines/risk calculators for the primary prevention of cardiovascular disease have been developed, which could make decisions for or against therapy easier... - Strategies to reduce alcohol misuse in primary careP Truman
South Birmingham Primary Care Trust, Birmingham
Nurs Stand 20:41-4. 2006..Nurses in primary care are well placed to develop, implement and evaluate alcohol misuse reduction strategies... - New developments in the management of STDsLynn G Kirkland
University of Tennessee Health Science Center at Memphis, College of Nursing, Memphis, TN, USA
Nurse Pract 31:12-21; quiz 22-3. 2006..To assist clinicians in preventing and treating STDs, the CDC recently published new guidelines that not only emphasize treatment, but also prevention strategies and diagnostic recommendations... - OsteoporosisRebecca Hawkins
St. Mary Medical Center, Walla Walla, WA, USA
Cancer Nurs 29:78-82. 2006 - Reducing the growing burden of cardiovascular disease in the developing worldThomas A Gaziano
Division of Cardiology, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts, USA
Health Aff (Millwood) 26:13-24. 2007..Despite the burden, cost-effective strategies exist at the population and individual levels for reducing CVD. Integral to all personal intervention strategies is an adequate assessment of the underlying risk of disease... - State of the heart: building science to improve women's cardiovascular healthAnne G Rosenfeld
School of Nursing, Oregon Health and Science University, Portland, USA
Commun Nurs Res 39:33-50. 2006 - Healthy endothelium: the scientific basis for cardiovascular health promotion and chronic disease preventionGeorge A Mensah
National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, CDC, Mailstop K 40, 4770 Buford Highway NE, Atlanta, GA 30341 3717, USA
Vascul Pharmacol 46:310-4. 2007..Increased collaboration among basic scientists, clinician-investigators, prevention research centers, and all public health practitioners is needed to facilitate the translation of the endothelial science into practice... - What are the chances? Risk in the real worldSuzanne M Mahon
Division of Hematology Oncology, Department of Internal Medicine at Saint Louis University, Missouri, USA
Clin J Oncol Nurs 10:99-101, 107. 2006..This column will provide a focus on wellness for patients with cancer, their caretakers, and health professionals. This inaugural column provides a review of a basic epidemiologic principle--risk assessment, which is central to wellness... - Cutaneous melanoma: public health approach to early detectionMartin A Weinstock
Dermatoepidemiology Unit, V A Medical Center 111D, 830 Chalkstone Avenue, Providence, RI 02908, USA
Dermatol Ther 19:26-31. 2006..Together, patients and clinicians can improve early detection to reduce melanoma-related mortality... - Vascular endothelium summary statement II: Cardiovascular disease prevention and controlGeorge A Mensah
National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, CDC, Mailstop K 40, 4770 Buford Highway NE, Atlanta, GA 30341 3717, USA
Vascul Pharmacol 46:318-20. 2007..This summary statement addresses the current state of the science with respect to endothelial dysfunction and CVD pathogenesis, diagnostic evaluation, and suggested strategies for public health practice and research...
Research Grants
- Heart Failure Evaluation in Post-Menopausal Women: The Women's Health InitiativeLiviu Klein; Fiscal Year: 2007..In addition, there are no data examining HRT in primary prevention of CHF among post-menopausal women, or its effects on survival in women who develop CHF...
- A Randomized Efficacy Trial of Moms and Teens for Safe DatesVangie A Foshee; Fiscal Year: 2010..Objectives: The proposed study is to test the efficacy of a selective family-based program for the primary prevention of dating abuse perpetration targeted at adolescents who have been exposed to domestic violence...
- Vitamin D and Omega-3 Fatty Acids(VITAL Trial): Effects on FracturesMERYL SUSAN LEBOFF; Fiscal Year: 2010..Large primary prevention trials with high daily doses of vitamin D and/or omega-3 fatty acids in general populations (i.e...
- Venous thromboembolism among California cancer patientsHelen Chew; Fiscal Year: 2003..that use of anticoagulants, such as warfarin or low molecular weight heparin, may be beneficial in the primary prevention of VTE among cancer patients...
- Vitamin D and Fish Oil for Autoimmune Disease, Inflammation and Joint PainKaren H Costenbader; Fiscal Year: 2010..However, large primary prevention trials with adequate dosing in general populations (i.e...
- PENNSYLVANIA ABUSIVE HEAD TRAUMA PREVENTION PROGRAMMark Dias; Fiscal Year: 2007..1 per 1000 population, this represents approximately 1250 cases annually in the United States. An effective primary prevention strategy that would reduce the incidence of AHT would potentially save the lives of many children and ..
- Effects of Simvastatin on CSF AD biomarkers in cognitively normal subjectsGail Li; Fiscal Year: 2010b>Primary prevention of Alzheimer's disease (AD) promises great clinical and economic benefits but poses great challenges because the pathologic processes of AD start years or even decades prior to clinical symptoms of dementia...
- VITAL-DEP: Depression Endpoint Prevention in the VITamin D and OmegA-3 TriaLOLIVIA IFEOMA OKEREKE; Fiscal Year: 2010..RCT designed to evaluate the efficacy of vitamin D3 and marine omega-3 fatty acid supplements in the primary prevention of cardiovascular disease and cancer among 20,000 older U.S. men and women. We will address two primary aims...
- A Large Randomized Trial of Vitamin D, Omega-3 Fatty Acids and Cognitive DeclineJae H Kang; Fiscal Year: 2010..January 2010) to investigate the effects of vitamin D and marine omega-3 fatty acid supplements on the primary prevention of cardiovascular disease and cancer...
- Primary Prevention of Hypertension in Obese AdolescentsDaniel Feig; Fiscal Year: 2006....
- Intimate Partner Violence Among Low-Income Pregnant Women: Multilevel AnalysisQing Li; Fiscal Year: 2005..IPV in the transition to parenthood warrants special attention on risk assessment and primary prevention from an ecological perspective and an approach directed at the potential perpetrators...
- PSYCHOSOCIAL FACTORS IN SUDDEN CARDIAC DEATHSue Thomas; Fiscal Year: 2002..defibrillators (ICD) on the psychosocial status of heart failure (HF) patients who receive ICD as primary prevention for sudden cardiac death (SCD); and 4) compare the psychosocial impact of ICD with the impact of the other ..
- B VITAMIN ATHEROSCLEROSIS INTERVENTION TRAILHOWARD HODIS; Fiscal Year: 2004DESCRIPTION (adapted from the application): Although primary prevention strategies have focused on key modifiable risk factors for development and progression of atherosclerosis, such as hypercholesterolemia, coronary heart disease (CHD) ..
- Translating an Efficaious HPV Vaccine into the Control of Cervical CancerSharon Bond; Fiscal Year: 2007..2006 of an efficacious human papillomavirus (HPV) vaccine provides an unprecedented opportunity for the primary prevention of cervical cancer...