health care costs


Summary: The actual costs of providing services related to the delivery of health care, including the costs of procedures, therapies, and medications. It is differentiated from HEALTH EXPENDITURES, which refers to the amount of money paid for the services, and from fees, which refers to the amount charged, regardless of cost.

Top Publications

  1. ncbi Delivering affordable cancer care in high-income countries
    Richard Sullivan
    Kings Health Partners, King s College, Integrated Cancer Centre, Guy s Hospital Campus, London, UK
    Lancet Oncol 12:933-80. 2011
  2. pmc Multiple chronic conditions: prevalence, health consequences, and implications for quality, care management, and costs
    Christine Vogeli
    Institute for Health Policy in the Department of Medicine, Massachusetts General Hospital, Boston, MA, USA
    J Gen Intern Med 22:391-5. 2007
  3. ncbi Economic burden of cardiovascular diseases in the enlarged European Union
    Jose Leal
    Department of Public Health, Health Economics Research Centre, Oxford University, Old Road Campus, Oxford OX3 7LF, UK
    Eur Heart J 27:1610-9. 2006
  4. ncbi Cost of dengue cases in eight countries in the Americas and Asia: a prospective study
    Jose A Suaya
    Schneider Institutes for Health Policy, Heller School, Brandeis University, Waltham, Massachusetts 02454 9110, USA
    Am J Trop Med Hyg 80:846-55. 2009
  5. ncbi What are the economic consequences for households of illness and of paying for health care in low- and middle-income country contexts?
    Diane McIntyre
    Health Economics Unit, University of Cape Town, Cape Town, South Africa
    Soc Sci Med 62:858-65. 2006
  6. ncbi The burden of chronic low back pain: clinical comorbidities, treatment patterns, and health care costs in usual care settings
    Mugdha Gore
    Avalon Health Solutions, Inc, Philadelphia, PA 19102, USA
    Spine (Phila Pa 1976) 37:E668-77. 2012
  7. ncbi The irrelevance of inference: a decision-making approach to the stochastic evaluation of health care technologies
    K Claxton
    Commonwealth Fund of New York, Harvard Center for Risk Analysis, Harvard School of Public Health, Boston, MA, USA
    J Health Econ 18:341-64. 1999
  8. ncbi Principles of good practice for budget impact analysis: report of the ISPOR Task Force on good research practices--budget impact analysis
    Josephine A Mauskopf
    RTI Health Solutions, Research Triangle Park, NC, USA
    Value Health 10:336-47. 2007
  9. ncbi Common comorbidity scales were similar in their ability to predict health care costs and mortality
    Anthony J Perkins
    Indiana University Center for Aging Research, 1050 Wishard Boulevard, RG6, Indianapolis, IN 46202, USA
    J Clin Epidemiol 57:1040-8. 2004
  10. ncbi Improving primary care for patients with chronic illness: the chronic care model, Part 2
    Thomas Bodenheimer
    Family and Community Medicine, University of California, San Francisco, USA
    JAMA 288:1909-14. 2002

Detail Information

Publications370 found, 100 shown here

  1. ncbi Delivering affordable cancer care in high-income countries
    Richard Sullivan
    Kings Health Partners, King s College, Integrated Cancer Centre, Guy s Hospital Campus, London, UK
    Lancet Oncol 12:933-80. 2011
    ..The cancer profession and industry should take responsibility and not accept a substandard evidence base and an ethos of very small benefit at whatever cost; rather, we need delivery of fair prices and real value from new technologies...
  2. pmc Multiple chronic conditions: prevalence, health consequences, and implications for quality, care management, and costs
    Christine Vogeli
    Institute for Health Policy in the Department of Medicine, Massachusetts General Hospital, Boston, MA, USA
    J Gen Intern Med 22:391-5. 2007
  3. ncbi Economic burden of cardiovascular diseases in the enlarged European Union
    Jose Leal
    Department of Public Health, Health Economics Research Centre, Oxford University, Old Road Campus, Oxford OX3 7LF, UK
    Eur Heart J 27:1610-9. 2006
  4. ncbi Cost of dengue cases in eight countries in the Americas and Asia: a prospective study
    Jose A Suaya
    Schneider Institutes for Health Policy, Heller School, Brandeis University, Waltham, Massachusetts 02454 9110, USA
    Am J Trop Med Hyg 80:846-55. 2009
    ..8 billion, and incorporating costs of dengue surveillance and vector control would raise the amount further. Dengue imposes substantial costs on both the health sector and the overall economy...
  5. ncbi What are the economic consequences for households of illness and of paying for health care in low- and middle-income country contexts?
    Diane McIntyre
    Health Economics Unit, University of Cape Town, Cape Town, South Africa
    Soc Sci Med 62:858-65. 2006
  6. ncbi The burden of chronic low back pain: clinical comorbidities, treatment patterns, and health care costs in usual care settings
    Mugdha Gore
    Avalon Health Solutions, Inc, Philadelphia, PA 19102, USA
    Spine (Phila Pa 1976) 37:E668-77. 2012
    ..Retrospective analysis of an insurance claims database...
  7. ncbi The irrelevance of inference: a decision-making approach to the stochastic evaluation of health care technologies
    K Claxton
    Commonwealth Fund of New York, Harvard Center for Risk Analysis, Harvard School of Public Health, Boston, MA, USA
    J Health Econ 18:341-64. 1999
    ..It also ensures that the type of information acquired is driven by the objectives of the health care system, is consistent with the budget constraint on service provision and that research is designed efficiently...
  8. ncbi Principles of good practice for budget impact analysis: report of the ISPOR Task Force on good research practices--budget impact analysis
    Josephine A Mauskopf
    RTI Health Solutions, Research Triangle Park, NC, USA
    Value Health 10:336-47. 2007
    ..The objective of this report is to present guidance on methodologies for those undertaking such analyses or for those reviewing the results of such analyses...
  9. ncbi Common comorbidity scales were similar in their ability to predict health care costs and mortality
    Anthony J Perkins
    Indiana University Center for Aging Research, 1050 Wishard Boulevard, RG6, Indianapolis, IN 46202, USA
    J Clin Epidemiol 57:1040-8. 2004
    ..measures of medical comorbidity (ambulatory care groups [ACGs], Charlson comorbidity index, chronic disease score, number of prescribed medications, and number of chronic diseases) to predict mortality and health care costs over 1 year.
  10. ncbi Improving primary care for patients with chronic illness: the chronic care model, Part 2
    Thomas Bodenheimer
    Family and Community Medicine, University of California, San Francisco, USA
    JAMA 288:1909-14. 2002 model can improve the management of chronic conditions (using diabetes as an example) and reduce health care costs. Thirty-two of 39 studies found that interventions based on chronic care model components improved at least ..
  11. ncbi A randomized trial of a telephone care-management strategy
    David E Wennberg
    Health Dialog Services, Boston, USA
    N Engl J Med 363:1245-55. 2010
    ..The effect of such a strategy on health care costs remains controversial.
  12. pmc When to start antiretroviral therapy in resource-limited settings
    Rochelle P Walensky
    Massachusetts General Hospital, Brigham and Women s Hospital, Harvard University Medical School, Harvard School of Public Health, and Boston University School of Public Health, Boston, Massachusetts 02114, USA
    Ann Intern Med 151:157-66. 2009
    ..The results of international clinical trials that are assessing when to initiate antiretroviral therapy (ART) will not be available for several years...
  13. ncbi Cost of disorders of the brain in Europe
    Patrik Andlin-Sobocki
    Stockholm Health Economics, Stockholm, Sweden
    Eur J Neurol 12:1-27. 2005
  14. ncbi Cost of stroke in the United Kingdom
    Omer Saka
    King s College London, Division of Health and Social Care Research, London SE1 3QD, UK
    Age Ageing 38:27-32. 2009
    ..this study aims to quantify the annual cost of illness of stroke to the UK economy...
  15. ncbi Cost-effectiveness of screening for HIV in the era of highly active antiretroviral therapy
    Gillian D Sanders
    Duke Clinical Research Institute, Duke University, Durham, NC 27715, USA
    N Engl J Med 352:570-85. 2005
    ..The costs, benefits, and cost-effectiveness of screening for human immunodeficiency virus (HIV) in health care settings during the era of highly active antiretroviral therapy (HAART) have not been determined...
  16. ncbi The lifetime cost of current human immunodeficiency virus care in the United States
    Bruce R Schackman
    Department of Public Health, Weill Medical College of Cornell University, New York, New York 10021, USA
    Med Care 44:990-7. 2006
    ..We sought to project the lifetime cost of medical care for human immunodefiency virus (HIV)-infected adults using current antiretroviral therapy (ART) standards...
  17. ncbi The economic burden of non-influenza-related viral respiratory tract infection in the United States
    A Mark Fendrick
    Division of General Internal Medicine, Department of Internal Medicine, School of Medicine, University of Michigan, 300 N Ingalls Bldg, Room 7E06, Ann Arbor, MI 48109 0376, USA
    Arch Intern Med 163:487-94. 2003
    ..Our objectives were to obtain an updated incidence of non-influenza-related VRTI in the United States and to quantify the health care resource use (direct costs) and productivity losses (indirect costs) associated with these infections...
  18. ncbi National health care costs of peripheral arterial disease in the Medicare population
    Alan T Hirsch
    Division of Epidemiology and Community Health, University of Minnesota School of Public Health, Minneapolis, MN 55454 1015, USA
    Vasc Med 13:209-15. 2008
    ..PAD prevalence as only approximately one-third of the population with known PAD had detectable PAD-related health care costs in our analysis...
  19. ncbi Cost of schizophrenia in England
    Roshni Mangalore
    PSSRU, London School of Economics and Political Science, Houghton Street, London WC2A 2AE, UK
    J Ment Health Policy Econ 10:23-41. 2007
    ..Despite the wide-ranging financial and social burdens associated with schizophrenia, there have been few cost-of-illness studies of this illness in the UK...
  20. ncbi [Empirical standard costs for health economic evaluation in Germany -- a proposal by the working group methods in health economic evaluation]
    C Krauth
    Abt Epidemiologie, Sozialmedizin und Gesundheitssystemforschung, Medizinische Hochschule Hannover
    Gesundheitswesen 67:736-46. 2005
    Measurement of health care costs is a crucial task in health economic evaluation...
  21. ncbi Lumbar disc disorders and low-back pain: socioeconomic factors and consequences
    Jeffrey N Katz
    Section of Clinical Sciences, Division of Rheumatology, Immunology and Allergy, Brigham and Women s Hospital, 75 Francis Street, Boston, MA 02115, USA
    J Bone Joint Surg Am 88:21-4. 2006
    ..These methodologic challenges notwithstanding, the toll of lumbar disc disorders is enormous, underscoring the critical importance of identifying strategies to prevent these disorders and their consequences...
  22. ncbi The cost diary: a method to measure direct and indirect costs in cost-effectiveness research
    M E Goossens
    Institute for Rehabilitation Research, Hoensbroek, The Netherlands
    J Clin Epidemiol 53:688-95. 2000
    ..However, for physiotherapy contacts there were differences between the self-reported and insurance data. This study shows how the cost diary might be used successfully in cost-effectiveness studies...
  23. pmc Different screening strategies (single or dual) for the diagnosis of suspected latent tuberculosis: a cost effectiveness analysis
    Anil Pooran
    Division of Infection and Immunity, Centre for Infectious Diseases and International Health, University College London Medical School, University College London, 43 Cleveland Street, London W1T 4JF, UK
    BMC Pulm Med 10:7. 2010
  24. ncbi Expanded screening for HIV in the United States--an analysis of cost-effectiveness
    A David Paltiel
    Department of Epidemiology and Public Health, Yale School of Medicine, New Haven, Conn 06520 8034, USA
    N Engl J Med 352:586-95. 2005
    ..The effect of expanded screening for HIV is unknown in the era of effective antiretroviral therapy...
  25. ncbi Obesity and pregnancy: complications and cost
    F Galtier-Dereure
    Service d endocrinologie, Hopital Lapeyronie, CHU Montpellier, France
    Am J Clin Nutr 71:1242S-8S. 2000
    ..Preconception counseling, careful prenatal management, tight monitoring of weight gain, and long-term follow-up could minimize the social and economic consequences of pregnancies in overweight women...
  26. ncbi The direct and indirect cost burden of acute coronary syndrome
    Stephen S Johnston
    Thomson Reuters, Washington, DC, USA
    J Occup Environ Med 53:2-7. 2011
    Quantify the incremental health care costs and workplace absence and short-term disability costs, to payers and employers, of patients hospitalized for acute coronary syndrome (ACS).
  27. ncbi The economic burden of schizophrenia in the United States in 2002
    Eric Q Wu
    Analysis Group, Inc, Boston, MA 02199, USA
    J Clin Psychiatry 66:1122-9. 2005
    ..This study quantifies excess annual costs associated with schizophrenia patients in the United States in 2002 from a societal perspective...
  28. pmc Re-evaluating the burden of rabies in Africa and Asia
    Darryn L Knobel
    Centre for Tropical Veterinary Medicine, Royal Dick School of Veterinary Studies, University of Edinburgh, Easter Bush, Roslin, Midlothian EH25 9RG, Scotland
    Bull World Health Organ 83:360-8. 2005
    ..To quantify the public health and economic burden of endemic canine rabies in Africa and Asia...
  29. pmc Direct costs of chronic obstructive pulmonary disease among managed care patients
    Anand A Dalal
    US Health Outcomes, GlaxoSmithKline, Research Triangle Park, Durham, NC 27709, USA
    Int J Chron Obstruct Pulmon Dis 5:341-9. 2010
    ..To estimate patient- and episode-level direct costs of chronic obstructive pulmonary disease (COPD) among commercially insured patients in the US...
  30. ncbi Cost-of-illness studies: a guide to critical evaluation
    Allison Larg
    Discipline of Public Health, School of Population Health and Clinical Practice, The University of Adelaide, South Australia
    Pharmacoeconomics 29:653-71. 2011
    ..The intention is to equip a general audience with an understanding of the most important issues that influence the validity of a COI study, and the ability to recognize the most common limitations in such work...
  31. ncbi Economic cost of severe antisocial behaviour in children--and who pays it
    Renee Romeo
    Centre for the Economics of Mental Health Institute of Psychiatry, King s College, London, UK
    Br J Psychiatry 188:547-53. 2006
    ..Persistent antisocial behaviour is the most common mental health problem in childhood and has widespread effects, yet little is known about what it costs...
  32. ncbi Cost of care for elderly cancer patients in the United States
    K Robin Yabroff
    Health Services and Economics Branch Applied Research Program, Division of Cancer Control and Population Sciences, National Cancer Institute, Executive Plaza North, Rm 4005, 6130 Executive Blvd, MSC 7344, Bethesda, MD 20892 7344, USA
    J Natl Cancer Inst 100:630-41. 2008
    ..We estimated net costs of care for elderly cancer patients in the United States for the 18 most prevalent cancers and for all other tumor sites combined...
  33. ncbi One-year health care costs associated with delirium in the elderly population
    Douglas L Leslie
    Department of Health Administration and Policy, Medical University of South Carolina, 151 Rutledge Ave, Bldg B, PO Box 250961, Charleston, SC 29425, USA
    Arch Intern Med 168:27-32. 2008
    While delirium has been increasingly recognized as a serious and potentially preventable condition, its long-term implications are not well understood. This study determined the total 1-year health care costs associated with delirium.
  34. ncbi Incidence and economic burden of osteoporosis-related fractures in the United States, 2005-2025
    Russel Burge
    Procter and Gamble Pharmaceuticals and Personal Health, Mason, OH, USA
    J Bone Miner Res 22:465-75. 2007
    ..Total fractures were >2 million, costing nearly $17 billion in 2005. Men account for >25% of the burden. Rapid growth in the disease burden is projected among nonwhite populations...
  35. ncbi Health services use and health care costs of obese and nonobese individuals
    Marsha A Raebel
    Clinical Research Unit, Kaiser Permanente of Colorado, Denver, CO 80237, USA
    Arch Intern Med 164:2135-40. 2004
    ..Obesity has clinical and economic consequences. Few studies have compared health care resource utilization between age- and sex-matched obese and nonobese persons...
  36. ncbi Generalized anxiety disorder: prevalence, burden, and cost to society
    Hans Ulrich Wittchen
    Institute of Clinical Psychology and Psychotherapy, Technical University of Dresden, Germany
    Depress Anxiety 16:162-71. 2002
  37. ncbi Analgesic usage for low back pain: impact on health care costs and service use
    Molly T Vogt
    University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
    Spine (Phila Pa 1976) 30:1075-81. 2005
    ..Cross-sectional analysis of analgesic use by patients with low back pain (LBP)...
  38. ncbi Direct medical cost of influenza-related hospitalizations in children
    Ron Keren
    Children s Hospital of Philadelphia, 3535 Market St, Room 1524, Philadelphia, PA 19104, USA
    Pediatrics 118:e1321-7. 2006
    ..Our goal was to determine the cost of influenza-related hospitalization in children with community-acquired laboratory-confirmed influenza and to identify predictors of high hospitalization costs...
  39. ncbi Economic implications of hip fracture: health service use, institutional care and cost in Canada
    M E Wiktorowicz
    Departments of Epidemiology and Biostatistics and Political Science, University of Western Ontario, London, Ontario, Canada
    Osteoporos Int 12:271-8. 2001
    ..Annual economic implications of hip fracture in Canada are $650 million and are expected to rise to $2.4 billion by 2041...
  40. ncbi Estimation of total incremental health care costs in patients with atrial fibrillation in the United States
    Michael H Kim
    Division of Cardiology, Northwestern University, Feinberg School of Medicine, 251 E Huron Street, Chicago, IL 60611, USA
    Circ Cardiovasc Qual Outcomes 4:313-20. 2011
  41. ncbi Too much ado about two-part models and transformation? Comparing methods of modeling Medicare expenditures
    Melinda Beeuwkes Buntin
    RAND Health, Washington Office, 1200 South Hayes Street, Arlington, VA 22202 5050, USA
    J Health Econ 23:525-42. 2004
    ..It finds that four of the alternatives produce very similar results in practice. It then suggests an efficient method for researchers to use when selecting estimators of health care costs.
  42. ncbi Economic analysis of the Confronting COPD survey: an overview of results
    E F M Wouters
    Department of Pulmonology, University Hospital Maastricht, Maastricht, The Netherlands
    Respir Med 97:S3-14. 2003
  43. ncbi Prevalence and costs of chronic conditions in the VA health care system
    Wei Yu
    VA HSR and D Health Economics Resource Center, Center for Health Policy, Center for Primary Care and Outcomes Research, Stanford University, USA
    Med Care Res Rev 60:146S-167S. 2003
    ..2 million) of VA health care users had 3 or more of the 29 chronic conditions. These individuals accounted for 73 percent of the total cost. Overall, VA health care users have more chronic diseases than the general population...
  44. ncbi The outcomes and outpatient costs of different models of antiretroviral treatment delivery in South Africa
    Sydney Rosen
    Center for International Health and Development, Boston University, Boston, MA 02118, USA
    Trop Med Int Health 13:1005-15. 2008
    ..Estimate the average outpatient cost per patient in care and responding to treatment 1 year after initiation of antiretroviral therapy (ART) under different models of treatment delivery in South Africa...
  45. ncbi Health care utilization in chronic obstructive pulmonary disease. A case-control study in a health maintenance organization
    D W Mapel
    Epidemiology and Cancer Control Program, University of New Mexico Health Sciences Center, 2325 Camino de Salud NE, Albuquerque, NM 87131 5306, USA
    Arch Intern Med 160:2653-8. 2000
  46. ncbi Moderate and severe obesity have large differences in health care costs
    Tatiana Andreyeva
    RAND Graduate School, 1776 Main Street, Santa Monica, CA 90401, USA
    Obes Res 12:1936-43. 2004
    ..To analyze health care use and expenditures associated with varying degrees of obesity for a nationally representative sample of individuals 54 to 69 years old...
  47. ncbi Cost-of-illness studies of dementia: a systematic review focusing on stage dependency of costs
    W Quentin
    Health Economics Research Unit, Department of Psychiatry, University of Leipzig, Liebigstrasse 26, Leipzig, Germany
    Acta Psychiatr Scand 121:243-59. 2010
    ..To review cost-of-illness (COI) studies of dementia from Europe and North America which report costs per patient by disease stage...
  48. pmc Direct health care costs of Crohn's disease and ulcerative colitis in US children and adults
    Michael D Kappelman
    Division of Pediatric Gastroenterology, Department of Pediatrics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA
    Gastroenterology 135:1907-13. 2008
    Data regarding the health care costs of inflammatory bowel disease (IBD) in the United States are limited...
  49. ncbi The trend in total cost of back pain in The Netherlands in the period 2002 to 2007
    Ludeke C Lambeek
    EMGO Institute for Health and Care Research, Department of Public and Occupational Health, VU University Medical Center, Amsterdam, The Netherlands
    Spine (Phila Pa 1976) 36:1050-8. 2011
    ..Cost of illness study...
  50. ncbi Societal consequences of falls in the older population: injuries, healthcare costs, and long-term reduced quality of life
    Klaas A Hartholt
    Department of Surgery Traumatology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands
    J Trauma 71:748-53. 2011
    ..The aim of this cohort study was to determine the incidence, costs, and quality of life for fall-related injuries in the older Dutch population presenting at the emergency department...
  51. ncbi What do we know about the economic impact of fetal alcohol spectrum disorder? A systematic literature review
    Svetlana Popova
    Social and Epidemiological Research Department, Centre for Addiction and Mental Health, Toronto, ON, Canada
    Alcohol Alcohol 46:490-7. 2011
    ..The objective of this study was to conduct a systematic review of the literature related to the measurement of the economic impact of Fetal Alcohol Spectrum Disorder (FASD) in different countries and to categorize the available literature...
  52. ncbi Dementia care costs and outcomes: a systematic review
    Martin Knapp
    Centre for the Economics of Mental Health, Institute of Psychiatry at King s College London, London, UK
    Int J Geriatr Psychiatry 28:551-61. 2013
    ..We reviewed evidence on the cost-effectiveness of prevention, care and treatment strategies in relation to dementia...
  53. pmc The public health implications of asthma
    Jean Bousquet
    Clinique des Maladies Respiratoires, Hopital Arnaud de Villeneuve, CHU Montpellier, 34295 Montpellier cedex 05, France
    Bull World Health Organ 83:548-54. 2005
    ..This paper presents a discussion of the burden of asthma and its socioeconomic implications and proposes a model to predict the costs incurred by the disease...
  54. ncbi Single-pill vs free-equivalent combination therapies for hypertension: a meta-analysis of health care costs and adherence
    Beth Sherrill
    RTI Health Solutions, Research Triangle Park, NC, USA
    J Clin Hypertens (Greenwich) 13:898-909. 2011
    ..The mean difference in combined total annual all-cause and hypertension-related health care costs was $1357 (95% confidence interval [CI], $778-$1935) lower in favor of SPC than FEC groups...
  55. ncbi The cost of health care for children and adults with sickle cell disease
    Teresa L Kauf
    Department of Pharmaceutical Outcomes and Policy, College of Pharmacy, University of Florida, Gainesville, Florida, USA
    Am J Hematol 84:323-7. 2009
    ..Across the 4,294 patient samples, total health care costs generally rose with age, from $892 to $2,562 per patient-month in the 0-9- and 50-64-year age groups, ..
  56. pmc Two-tier charging in Maputo Central Hospital: costs, revenues and effects on equity of access to hospital services
    Barbara McPake
    Institute for International Health and Development, Queen Margaret University, Queen Margaret University Drive, Musselburgh, EH21 6UU, UK
    BMC Health Serv Res 11:143. 2011
  57. ncbi Male circumcision for HIV prevention in sub-Saharan Africa: who, what and when?
    Richard G White
    London School of Hygiene and Tropical Medicine, London, UK
    AIDS 22:1841-50. 2008
    ..We explore how the population-level impact of circumcision varies by target age group, coverage, time-to-scale-up, level of risk compensation and circumcision of HIV infected men...
  58. pmc The impact of obesity on health care costs among persons with schizophrenia
    Lydia A Chwastiak
    Department of Psychiatry, Yale School of Medicine, New Haven, CT 06519, USA
    Gen Hosp Psychiatry 31:1-7. 2009
    ..Obesity is the second leading cause of preventable death in the United States and is twice as common among individuals with schizophrenia as the general population...
  59. ncbi An overview of methods and applications to value informal care in economic evaluations of healthcare
    Marc A Koopmanschap
    Department of Health Policy and Management iBMG, Erasmus MC Rotterdam, Rotterdam, The Netherlands
    Pharmacoeconomics 26:269-80. 2008
    ..Using broader, non-monetary valuation techniques, such as the CarerQol instrument, requires a broader evaluation framework than cost-effectiveness/cost-utility analysis, such as cost-consequence or multi-criteria analysis...
  60. ncbi Direct medical costs of COPD--an excess cost approach based on two population-based studies
    Petra Menn
    Institute of Health Economics and Health Care Management, Helmholtz Zentrum Muenchen, Ingolstaedter Landstr 1, 85764 Neuherberg, Germany
    Respir Med 106:540-8. 2012
    ..While it is known that severe COPD has substantial economic consequences, evidence on resource use and costs in mild disease is scarce. The objective of this study was to investigate excess costs of early stages of COPD...
  61. ncbi The costs of type 2 diabetes mellitus outpatient care in the Brazilian public health system
    Luciana R Bahia
    Universidade do Estado do Rio de Janeiro, Rio de Janeiro, Brazil
    Value Health 14:S137-40. 2011
    The prevalence of type 2 diabetes has shown a significant increase in parallel with health care costs. The objective of the Brazilian Study on Diabetes Costs (ESCUDI study) was to estimate direct and indirect costs of type 2 diabetes ..
  62. ncbi Rotavirus vaccine and health care utilization for diarrhea in U.S. children
    Jennifer E Cortes
    Epidemic Intelligence Service, Office of Workforce and Career Development, Division of Viral Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    N Engl J Med 365:1108-17. 2011
    ..Routine vaccination of U.S. infants with pentavalent rotavirus vaccine (RV5) began in 2006...
  63. pmc The Active for Life Year 5 (AFLY5) school based cluster randomised controlled trial: study protocol for a randomized controlled trial
    Debbie A Lawlor
    MRC Centre for Causal Analyses in Translational Epidemiology, University of Bristol, UK
    Trials 12:181. 2011
  64. pmc Health care costs associated with hepatitis C: a longitudinal cohort study
    Mel Krajden
    BC Centre for Disease Control, Vancouver, British Columbia
    Can J Gastroenterol 24:717-26. 2010
    ..Disease-specific estimates of medical costs are important for health policy decision making...
  65. ncbi Predictors of costs of care in Alzheimer's disease: a multinational sample of 1222 patients
    Anders Gustavsson
    Alzheimer s Disease Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Huddinge, Sweden
    Alzheimers Dement 7:318-27. 2011
    ..We aimed to identify what measures of disease severity are the most important predictors of societal costs of care and whether their relationship differs across countries...
  66. pmc The economic burden of child maltreatment in the United States and implications for prevention
    Xiangming Fang
    National Center for Injury Prevention and Control, Centers for Disease Control and Prevention, 4770 Buford Highway, Atlanta, GA 30341, USA
    Child Abuse Negl 36:156-65. 2012
    ..To present new estimates of the average lifetime costs per child maltreatment victim and aggregate lifetime costs for all new child maltreatment cases incurred in 2008 using an incidence-based approach...
  67. ncbi Osteoporotic fractures: a systematic review of U.S. healthcare costs and resource utilization
    Sangeeta Budhia
    Heron Evidence Development Ltd, Luton, UK
    Pharmacoeconomics 30:147-70. 2012
    ..S. The variability in the cost estimates highlights the importance of comparing the methodologies and the types of costs used when choosing an appropriate unit cost for economic modelling...
  68. pmc The impact of genital warts: loss of quality of life and cost of treatment in eight sexual health clinics in the UK
    S C Woodhall
    Hull York Medical School, University of York, York, UK
    Sex Transm Infect 87:458-63. 2011
    ..To estimate the loss of quality of life and cost of treatment associated with genital warts seen in sexual health clinics...
  69. pmc Health care burden and cost associated with fetal alcohol syndrome: based on official Canadian data
    Svetlana Popova
    Social and Epidemiological Research Department, Centre for Addiction and Mental Health, Toronto, Ontario, Canada
    PLoS ONE 7:e43024. 2012 gain an understanding on the health care utilization and the mortality rate for individuals diagnosed with FAS, as well as to estimate the associated health care costs in Canada for the most recent available fiscal year (2008-2009).
  70. pmc Cost-effectiveness of parenteral artesunate for treating children with severe malaria in sub-Saharan Africa
    Yoel Lubell
    Faculty of Tropical Medicine, Mahidol University, 420 6 Ratchawithi Road, Bangkok, 10400, Thailand
    Bull World Health Organ 89:504-12. 2011
    ..To explore the cost-effectiveness of parenteral artesunate for the treatment of severe malaria in children and its potential impact on hospital budgets...
  71. pmc Good agreement between questionnaire and administrative databases for health care use and costs in patients with osteoarthritis
    Daniel Pinto
    Centre for Physiotherapy Research, School of Physiotherapy, University of Otago, Dunedin 9054, New Zealand
    BMC Med Res Methodol 11:45. 2011
    Estimating costs is essential to the economic analysis of health care programs. Health care costs are often captured from administrative databases or by patient report...
  72. ncbi Dementia case management effectiveness on health care costs and resource utilization: a systematic review of randomized controlled trials
    C Pimouguet
    INSERM, U 897, and Université Victor Segalen Bordeaux 2, 146 rue Leo Saignat, 33 076 Bordeaux Cedex, France
    J Nutr Health Aging 14:669-76. 2010
    ..Further research should focus on determining subgroups of caregivers who could benefit the most from case management...
  73. ncbi The evolving cost of HIV in South Africa: changes in health care cost with duration on antiretroviral therapy for public sector patients
    Guy Harling
    Desmond Tutu HIV Centre, Institute of Infectious Disease and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa
    J Acquir Immune Defic Syndr 45:348-54. 2007
    ..This analysis suggests that the total cost of treatment for patients on ART falls by almost half after 1 year, largely attributable to a reduction in hospital costs...
  74. ncbi Cost of gestational diabetes-related antenatal visits in health care based on the Finnish Medical Birth Register
    Päivi Kolu
    UKK Institute for Health Promotion, Tampere, Finland
    Prim Care Diabetes 5:139-41. 2011
    ..Costs among all GDM risk groups were 10-41% larger than non-risk groups. Primary health care is needed to reduce special health care costs related to GDM.
  75. ncbi Antiretroviral therapy adherence, medication use, and health care costs during 3 years of a community pharmacy medication therapy management program for Medi-Cal beneficiaries with HIV/AIDS
    Jan D Hirsch
    Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, 9500 Gilman Dr, Mail Code 0714, La Jolla, CA 92093 0714, USA
    J Manag Care Pharm 17:213-23. 2011
  76. ncbi Incremental third-party costs associated with COPD exacerbations: a retrospective claims analysis
    Andrew P Yu
    Analysis Group Inc, Boston, MA, USA
    J Med Econ 14:315-23. 2011
    ..Exacerbations are a major contributor to the large burden of treating chronic obstructive pulmonary disease (COPD). Estimates of exacerbation costs in the United States are limited...
  77. ncbi International comparison of stroke cost studies
    Silvia M A A Evers
    Care and Public Health Research Institute CAPHRI of Maastricht University, Maastricht University, Faculty of Health Sciences, Maastricht, The Netherlands
    Stroke 35:1209-15. 2004
  78. ncbi Cost of stroke in Australia from a societal perspective: results from the North East Melbourne Stroke Incidence Study (NEMESIS)
    H M Dewey
    National Stroke Research Institute and the Neurology Department, Austin and Repatriation Medical Centre, Heidelberg, Australia
    Stroke 32:2409-16. 2001
    ..The purpose of this study was to determine the patterns of resource use among stroke patients and to estimate the total costs (direct service use and indirect production losses) of stroke (excluding SAH) in Australia for 1997...
  79. ncbi Economic burden associated with patients diagnosed with hepatitis C
    Jeffrey S McCombs
    School of Pharmacy, University of Southern California, Los Angeles, 90089 9004, USA
    Clin Ther 33:1268-80. 2011
    ..Data documenting the incremental economic and health burden of patients with HCV relative to those who are not infected with HCV will be required to evaluate the comparative effectiveness of these new therapies...
  80. ncbi A systematic review of the cost and cost effectiveness of treatment for multidrug-resistant tuberculosis
    Christopher Fitzpatrick
    Stop TB Department, World Health Organization, Geneva, Switzerland
    Pharmacoeconomics 30:63-80. 2012
    ..Evidence relevant to decisions about whether to scale-up treatment for MDR-TB includes cost and cost-effectiveness data. Up to 2010, no systematic review of this evidence has been available...
  81. ncbi Economic and humanistic burden of external genital warts
    Adam J N Raymakers
    Collaboration for Outcomes Research and Evaluation, Faculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, BC, Canada
    Pharmacoeconomics 30:1-16. 2012
    ..Our study also highlights the dearth of information on the impact of EGW on the QOL and productivity of patients...
  82. ncbi Predicting who will use intensive social care: case finding tools based on linked health and social care data
    Martin Bardsley
    The Nuffield Trust, 59 New Cavendish Street, London W1G 7LP, UK
    Age Ageing 40:265-70. 2011
    ..the costs of delivering health and social care services are rising as the population ages and more people live with chronic diseases...
  83. ncbi Projected cost-effectiveness of smoking cessation interventions in patients hospitalized with myocardial infarction
    Joseph A Ladapo
    Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
    Arch Intern Med 171:39-45. 2011
    ..Supportive contact after discharge improves quit rates but is rarely used...
  84. ncbi The global costs of schizophrenia
    Martin Knapp
    Centre for the Economics of Mental Health, Health Services Research Department, Institute of Psychiatry, De Crespigny Park, London
    Schizophr Bull 30:279-93. 2004
    ..Such information helps us to understand the health, health care, economic, and policy importance of schizophrenia, and to better interpret and explain the large within- and across-country differences that exist...
  85. ncbi Costs of Parkinson's disease in eastern Europe: a Czech cohort study
    Yaroslav Winter
    Dept of Neurology, Philipps University, Marburg, Germany
    Parkinsonism Relat Disord 16:51-6. 2010
    ..More intensive government support for patients with chronic diseases such as PD and the development of disease-management programs that incorporate both the clinical and economic effects of PD treatment are needed...
  86. ncbi The impact of prevention on reducing the burden of cardiovascular disease
    Richard Kahn
    American Diabetes Association, Alexandria, VA, USA
    Circulation 118:576-85. 2008
    ..We therefore determined the effects of 11 nationally recommended prevention activities on CVD-related morbidity, mortality, and costs in the United States...
  87. pmc Why do some women still prefer traditional birth attendants and home delivery?: a qualitative study on delivery care services in West Java Province, Indonesia
    Christiana R Titaley
    Sydney School of Public Health, Edward Ford Building A27, University of Sydney, NSW 2006, Australia
    BMC Pregnancy Childbirth 10:43. 2010
    ..This study aims to explore the perspectives of community members and health workers about the use of delivery care services in six villages of West Java Province...
  88. ncbi Direct economic burden of chronic hepatitis C virus in a United States managed care population
    Keith L Davis
    Health Economics, RTI Health Solutions, Research Triangle Park, NC 27709, USA
    J Clin Gastroenterol 45:e17-24. 2011
    ..To estimate all-cause and disease-related resource utilization and costs among managed care enrollees with chronic hepatitis C virus (HCV)...
  89. ncbi Cross sectional observational study on the societal costs of Alzheimer's disease
    J Mesterton
    i3 Innovus, Klarabergsviadukten 90 Hus D, 111 37 Stockholm, Sweden
    Curr Alzheimer Res 7:358-67. 2010
    ..There is today limited data on resource utilization and quality of life in AD, in particular in the severe stage of disease...
  90. ncbi The cost of overweight and obesity in Australia
    Stephen Colagiuri
    Boden Institute of Obesity, Nutrition and Exercise, University of Sydney, Sydney, NSW, Australia
    Med J Aust 192:260-4. 2010
    To assess and compare health care costs for normal-weight, overweight and obese Australians.
  91. ncbi Treatment persistence with adalimumab, etanercept, or infliximab in combination with methotrexate and the effects on health care costs in patients with rheumatoid arthritis
    Boxiong Tang
    Medical Affairs, Centocor Ortho Biotech Services, LLC, Horsham, Pennsylvania 19044, USA
    Clin Ther 30:1375-84. 2008
    ..Information on patient persistence with biologic anti-TNF therapies is limited, and the effects of persistence on the costs of therapy are unknown...
  92. ncbi The impact of psoriasis on health care costs and patient work loss
    Joseph F Fowler
    University of Louisville, Louisville, Kentucky, USA
    J Am Acad Dermatol 59:772-80. 2008
    ..There are few comprehensive estimates of the cost of psoriasis in the United States...
  93. pmc Cost of illness in rheumatoid arthritis, ankylosing spondylitis, psoriatic arthritis and systemic lupus erythematosus in Germany
    D Huscher
    German Rheumatism Research Centre, Berlin, Germany
    Ann Rheum Dis 65:1175-83. 2006
  94. pmc Using information on clinical conditions to predict high-cost patients
    John A Fleishman
    Center for Financing, Access, and Cost Trends, Agency for Healthcare Research and Quality, 540 Gaither Road, Rockville, MD 20850, USA
    Health Serv Res 45:532-52. 2010
    ..To compare the ability of different models to predict prospectively whether someone will incur high medical expenditures...
  95. ncbi Physical inactivity: direct cost to a health plan
    Nancy A Garrett
    Health Services Analysis and Reporting, HealthPartners, Minneapolis, Minnesota 55440, USA
    Am J Prev Med 27:304-9. 2004
    ..The purpose of this study was to estimate the total medical expenditures attributable to physical inactivity patterns among members of a large health plan, Blue Cross Blue Shield of Minnesota...
  96. ncbi Cost-effectiveness of psychotherapy for cluster B personality disorders
    Djøra I Soeteman
    Department of Medical Psychology and Psychotherapy, Erasmus Medical Center, Rotterdam, The Netherlands
    Br J Psychiatry 196:396-403. 2010
    ..Recommendations on current clinical guidelines are informed by limited economic evidence...
  97. ncbi Cost effectiveness of revision total knee arthroplasty
    Alexander W R Burns
    London Health Sciences Centre, University of Western Ontario, London, Ontario, Canada
    Clin Orthop Relat Res 446:29-33. 2006
    ..Level of Evidence: Prognostic study, level II-1 (prospective study). See Guidelines for Authors for complete description of levels of evidence...
  98. ncbi Measuring costs: administrative claims data, clinical trials, and beyond
    Ruth Etzioni
    Fred Hutchinson Cancer Research Center, Seattle, Washington, USA
    Med Care 40:III63-72. 2002
    ..Accurate estimation of medical care costs raises a host of issues, both practical and methodological...
  99. ncbi Uncertainty assessment of input parameters for economic evaluation: Gauss's error propagation, an alternative to established methods
    Björn Stollenwerk
    Institute of Health Economics and Clinical Epidemiology of the University of Cologne, Gleueler Strasse Cologne, Germany
    Med Decis Making 30:304-13. 2010
    ..Furthermore, it succeeded the claims data example, a case in which the established methods failed. In conclusion, the error propagation law is a useful extension of parameter uncertainty assessment...
  100. ncbi Impact of postherpetic neuralgia and painful diabetic peripheral neuropathy on health care costs
    Robert H Dworkin
    Departments of Anesthesiology and Neurology, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
    J Pain 11:360-8. 2010
    Knowledge of the health care costs associated with neuropathic pain is limited...
  101. ncbi Cost of illness of adult diabetes mellitus underestimated if comorbidity is not considered
    A Norlund
    Swedish Council on Technology Assessment in Health Care, Stockholm, Sweden
    J Intern Med 250:57-65. 2001
    ..To determine costs of illness for adult diabetes mellitus (DM), including complications caused by DM...

Research Grants86

  1. Understanding/ Treating Neuropsychiatric Symptoms of Pediatric Physical Illness
    Eva Szigethy; Fiscal Year: 2009
    ..intervention targeting emotional and cognitive processing compared to supportive non-directive therapy at: (a) improving emotional well being;(b) alleviating physical symptoms; and (c) reducing health care costs.
  2. Immune Regulation of Bone Homeostasis
    MERVYN NEALE WEITZMANN; Fiscal Year: 2012
  3. Hypothalamic Orexin Role in Menopause-Associated Hot Flashes and Mood/Sleep Disru
    PHILIP LEE JOHNSON; Fiscal Year: 2013
    ..menopausal symptoms have a significant financial impact in the workplace through lost work days and direct health care costs for medical services...
  4. Reactive (AA)Amyloidosis
    Merrill D Benson; Fiscal Year: 2013
    ..amyloidosis very often leads to renal failure, chronic dialysis is required and significantly adds to health care costs in patients with this progressive fatal disease...
  5. Regulation of mural cells during pulmonary capillary formation
    Stephen E McGowan; Fiscal Year: 2013
    ..pulmonary abnormality, emphysema, are common and disproportionately contribute to hospitalizations and health care costs among veterans...
  6. The role of Fli1 in T cell function and the pathogenesis of lupus
    Tamara K Nowling; Fiscal Year: 2011
    ..screening methods and interventions for the treatment of this disease;thus relieving the burden of increased health care costs for these patients and improving their quality of life...
  7. Behavioral Activation Therapy for Rural Veterans with Diabetes and Depression
    Aanand Dinkar Naik; Fiscal Year: 2013
    ..Diabetic patients with co-occurring depression have higher health care costs, poorer self management, and poorer glycemic control than diabetics without depression...
  8. Statin modulation of immunotherapy for Alzheimer disease
    Jun Tan; Fiscal Year: 2012
    ..This will be tested by comparing behavior and brain health in several mouse groups including: A( vaccinated (alone) and those treated with lovastatin plus A( vaccination. ..
  9. Analyzer for Monitoring Personal Environmental Exposure to Fluids and Materials
    MATTHEW CUSACK; Fiscal Year: 2010
    ..Other applications for this technology are expected to be part of the GEI, the National Children's Study (NCS), in workplace assessments of occupational exposure, hospitals, or other medical or research settings. ..
  10. Pathogenesis of the Metabolic Syndrome
    W Timothy Garvey; Fiscal Year: 2013
    ..and cardiovascular disease, and these diseases are responsible for a huge burden of patient suffering and health care costs among veterans and the US population in general...
  11. Therapeutic Effect of a Novel Antioxidant on Degenerative Eye Disorders
    Nuran Ercal; Fiscal Year: 2012
    ..NACA eye drops would represent an alternative to costly cataract surgery, reduce health care costs related to age-related eye diseases and greatly improve the quality of life of people affected by these ..
  12. Diagnosis of Subglottic Stenosis and Edema in Neonates Using OCT
    Brian Wong; Fiscal Year: 2013
    ..Development of an office-based treatment technology to diagnosis subglottic stenosis or monitor its development would reduce the need for morbidity and decrease health care costs.
  13. Mechanism Underlying Nitrite Sensitivity of Mucoid Pseudomonas in COPD
    Daniel J Hassett; Fiscal Year: 2013
    ..Improved treatment options, in this case the use of sodium nitrite for the management of COPD exacerbations precipitated by PA infection are needed to reduce mortality and morbidity. ..
  14. Mitochondrial and Nuclear Mechanisms of Estrogen Receptor-Mediated Cardioprotecti
    DONNA HOPE KORZICK; Fiscal Year: 2012
    ..will undoubtedly require increased allocation of medical resources, raising the economic burden of health care costs for all Americans...
  15. Role of GDNF in the regulation of hepatic steatosis
    SHANTHI K SRINIVASAN; Fiscal Year: 2013
    ..Strategies to prevent and treat obesity can reduce obesity related complications (like NAFLD) and health care costs. Identification of new therapies for hepatic steatosis will directly benefit the veteran population...
  16. Epigenetic effects of developmental endocrine disruptor exposure in the ovary
    Mehmet Uzumcu; Fiscal Year: 2010
    ..can lead to better prevention diagnosis, and therapies, thereby improving public health and reducing health care costs. PUBLIC HEALTH RELEVANCE: Exposure to environmental endocrine-disrupting chemicals (EDCs), such as the ..
    L Jeannine Brady; Fiscal Year: 2013
    Dental caries results in 25-30 billion dollars in annual health care costs in the US and is caused by the pathogenic bacterium Streptococcus mutans...
  18. Imaging Nonlinear Absorption of Biomarkers for Improved Detection of Melanoma
    Warren S Warren; Fiscal Year: 2010
    ..Reducing false negatives would reduce cancer fatalities;reducing false positives reduces overall healthcare costs. ..
  19. Metabolic impact of fructose restriction in obese children
    Jean Marc Schwarz; Fiscal Year: 2013
    ..increase in the proportion of children with from obesity, diabetes, and metabolic syndrome, which drive up health care costs and contribute to premature mortality. The etiology(ies) of metabolic syndrome remain(s) unknown...
  20. Detection of Liver Fibrosis Using IVIM Diffusion and DCE MRI in HCV
    Bachir Taouli; Fiscal Year: 2013
    ..This disease is/will be the source of enormous health care costs and morbidity/mortality...
  21. Vitamin D3 Regulation of the Hypothalamic-Pituitary-Gonadal Axis
    Genevieve S Neal-Perry; Fiscal Year: 2012
    ..and the development of a relatively safe, inexpensive, biologically plausible yet simple medical intervention intended to eliminate disparities, to improve public health outcomes, and to reduce the burden of health care costs.
  22. Comparative Effectiveness Research in Pediatric Rheumatic Diseases: Leveraging CA
    CAROL A contact WALLACE; Fiscal Year: 2010
    ..effectiveness research, creating the evidence base for better care, which will translate into reduced health care costs, enabling American businesses to be more competitive globally...
  23. Localization and characterization of the Clostridium difficile biofilm
    Adam Driks; Fiscal Year: 2013
    ..In the US, it accounts for over $3.2 billion/year in health care costs in hospitals. Patients acquire C...
  24. Robot-Assisted MRI-Guided Prostate Biopsy
    Dan Stoianovici; Fiscal Year: 2010
    ..Unlike current biopsy technology that targets regions of the gland, the MRI-guided instrument will assist the physician target lesions of image abnormality. ..
  25. Effect of Ultrafiltration on Clinical Outcomes and Health-related Quality of Life
    KELLY VICTORIA LIANG; Fiscal Year: 2013
  26. Optimizing Chronic Disease Prevention and Management in Advanced Dementia
    Jennifer Tjia; Fiscal Year: 2010
  27. Foxf1 Transcription Factor in Development of Pulmonary Capillaries
    Vladimir V Kalinichenko; Fiscal Year: 2013
    ..BPD has long-term respiratory and neurodevelopmental complications that reach beyond childhood and increase health care costs. Given the lack of major improvements in prevention and treatment of BPD, there is a major need for ..
  28. Diet and Gastrointestinal Cancer Risk in African Americans and Rural Africans
    STEPHEN JD O'KEEFE; Fiscal Year: 2012
    ..manipulated to modify microbiota to promote mucosal health, and therefore reduce colon cancer risk, diminish health care costs related to diagnosis and treatment, and decrease the unacceptably high present morbidity and mortality from ..
  29. Misregulation of receptor tyrosine kinase signaling in PKD
    Jordan A Kreidberg; Fiscal Year: 2013
    ..major public health issue, and accounts for hundreds of millions (and perhaps over a billion) of dollars in health care costs, particularly for dialysis treatments and the cost of drugs that prevent transplant rejections, as well as ..
  30. Structure-function analyses on novel processes of type II vestibular hair cells
    Jennifer S Stone; Fiscal Year: 2013
    ..Studies of damaged vestibular organs will help uncover the relationship between normal and regenerated hair cells with processes and the potential of regenerated hair cells to restore function in balance and hearing disorders. ..
  31. Effect of Perinatal Diet on Developmental Programming of the Skeleton
    Mary L Bouxsein; Fiscal Year: 2010
    ..Establishing that maternal / perinatal diet influences peak bone mass acquisition may point to diet as a modifiable risk factor for adult bone disease. ..
  32. Click chemistry for novel antimicrobials against periodontal pathogens
    Valery V Fokin; Fiscal Year: 2010
    ..early stages, is not only important for overall health, but may also indirectly translate into lower total health care costs. Therefore, design and validation of novel non-surgical interventions and preventive strategies against ..
  33. Leptin function &resistance in midbrain VTA &SN in reward eating &obesity
    YI NONE ZHANG; Fiscal Year: 2013
    ..The long-range benefit from our study would be to reduce the ever-rising burden of long-term health care costs within the VA patient care system.
  34. Fast accurate ultrasensitive in vitro assay to determine BoNT potency &stability
    ARMIN H REITMAIR; Fiscal Year: 2012
  35. Multi-Organ Autonomic Electrophysiology in Parkinson Disease
    Samay Jain; Fiscal Year: 2013
  36. Lifestyle and Molecular Factors of Bone Health in Breast Cancer Survivors
    Song Yao; Fiscal Year: 2013
    ..In the Pathways Study, we now have an exceptional opportunity to address an important gap in breast cancer survivorship research, and to reduce the burden of AI-induced osteoporotic fractures in a real-world clinical setting. ..
  37. Development of a Wearable Passive Vibration Therapy System for the Lower Extremit
    JEFFREY MICHAEL LEISMER; Fiscal Year: 2010
  38. Novel Antithrombotic Diadenosine Tetraphosphate Analogs
    IVAN B YANACHKOV; Fiscal Year: 2013
    ..such as myocardial infarction and stroke, are among the leading causes of death, incapacitation, and rising health care costs in the developed world...
  39. High Throughput Screening of the Autoimmune Epitome
    Nancy J Olsen; Fiscal Year: 2010
    ..These conditions cause considerable morbidity and excess mortality, as well as direct and indirect health care costs in the tens of billions of dollars...
  40. Functional significance of Siglec-6, a novel leptin receptor, in human placental
    Virginia Winn; Fiscal Year: 2013
    ..The immediate US health care costs attributable to PE are estimated at $7 billion per year...
  41. Transplantation tolerance and immune function following mTOR inhibition.
    Jonathan D Powell; Fiscal Year: 2013
    ..cell anemia and other chronic anemias impose a huge burden of pain and suffering for patients and large health care costs related to hospitalizations and chronic transfusion/chelation therapy...
  42. Rapid, Highly Multiplexed and Sensitive Blood Test for Drug-resistant Bacteria
    ARMIN H REITMAIR; Fiscal Year: 2010
  43. North Lawndale Diabetes Community Action Project
    STEVEN contact WHITMAN; Fiscal Year: 2010
  44. Community Ambulation Following Hip Fracture
    Jay Magaziner; Fiscal Year: 2013
    ..PUBLIC HEALTH RELEVANCE: More than 325,000 hip fractures occur annually in the US, with associated health care costs estimated at $14-20 billion...
  45. Ethnic/Racial Variation in Intracerebral Hemorrhage (ERICH)
    Daniel Woo; Fiscal Year: 2013
    ..7 billion dollars of health care costs. African-Americans and Hispanics have twice the rate of this type of stroke than whites do and have this ..
  46. Developing Novel Dual CRF-R1/Orexin-1 Receptor Antagonists for Tobacco Dependence
    Belew Mekonnen; Fiscal Year: 2011
    ..annual economic burden of tobacco use had reached over $193 billion both in lost productivity and associated health care costs in the USA...
  47. Phase III Study Comparing Albumin and Hetastarch Therapy in Acute Lung Injury
    Gregory S Martin; Fiscal Year: 2013
    ..This trial will also provide requisite data for any subsequent clinical trials targeted at other clinically relevant outcomes, such as mortality, the duration of mechanical ventilation, or health-related quality of life. ..
  48. The Role of Lung Volumes in Nocturnal Asthma
    ROBERT LLEWELLYN OWENS; Fiscal Year: 2013
    ..This research can help delineate asthma pathogenesis and may help improve therapeutic options in this exceedingly common disease. ..
  49. Identification of stromal responses during castration-induced thymic regrowth.
    Howard T Petrie; Fiscal Year: 2013
    ..degeneration (atrophy) is thus of substantial importance for enhancing quality of life, and for decreasing health care costs in adults and the elderly...
  50. North Carolina Birth Defects Study To Evaluate Pregnancy Exposures (NC BD-STEPS)
    Andrew Olshan; Fiscal Year: 2013
    ..By including multiple study sites, BD-STEPS will aim for a study population that is representative of the US population in racial/ethnic composition. The project period is anticipated to be 8/1/2013 - 7/31/2018. ..
  51. Mitoenergetic Failure in Brain Aging
    Gregory J Brewer; Fiscal Year: 2013
    ..S. who will constitute 23% of the population in 2040, 70 million people. 13 million of these people are expected to have Alzheimer disease with expected health care costs of $250 billion.
  52. RCT of US versus CT for Patients in the ED with Suspected Renal Colic
    Rebecca Smith Bindman; Fiscal Year: 2010 the fastest growing component of medical spending in the United States, growing twice as fast as total health care costs. Remarkably few studies have compared the effectiveness of expensive imaging technologies...
  53. Blood Pressure -- Determinants &Controllers
    Allen W Cowley; Fiscal Year: 2012
    ..America leading to an increased incidence of stroke, heart, and renal disease, that contribute to escalating health care costs. The program reflects a long-standing experience of shared ideas in a synergistic environment aimed toward ..
  54. Cardiac Regeneration through Growth Factor Eluting Microrod Scaffolds
    Paul H Goldspink; Fiscal Year: 2013
    ..estimates are that heart failure accounts for approximately one million hospitalizations and $10 billion in health care costs in the United States per year...
  55. Triple Quadrupole/Linear Ion Trap LC-MS/MS for LPI
    Jan Frederik Stevens; Fiscal Year: 2010
    ..goal of these studies is to help prevent and treat human diseases by targeted diet and lifestyle modifications, thereby extending healthspan, improving personal and public health, and reducing health care costs in the United States.
  56. Novel CNS Target for Sleep-Wake and Psychiatric Disorders
    SCOTT MCNEAR THACHER; Fiscal Year: 2010
    ..Modulation of this transcriptional network could have a major impact in the area of CNS therapeutics. ..
  57. The Magnesium and Metabolic Syndrome Trial
    Stella Lucia Volpe; Fiscal Year: 2010
    ..If effective in improving insulin resistance in the metabolic syndrome, magnesium supplementation could have a great public health impact by delaying or preventing type 2 diabetes mellitus, and also in decreasing health care costs.
  58. NAPS2 Continuation Genome Wide Association Study of Pancreatitis
    DAVID CLEMENT WHITCOMB; Fiscal Year: 2011
    ..5 billion in health care costs. Recurrent acute (RAP) and chronic pancreatitis (CP) are complex, overlapping syndromes of pancreatic ..
  59. Coping Skills Training in Heart Failure: Outcomes and Mechanisms
    Andrew Sherwood; Fiscal Year: 2013
    ..evaluate a Coping Skills Intervention designed to enhance health-related behaviors and reduce psychological distress in heart failure patients, resulting in improved health status, better quality of life and lowered health care costs.
  60. Regulation of IL-6 mediated inflammation and tissue destruction by EGCG
    Salah Uddin Ahmed; Fiscal Year: 2013
    ..Successful completion of this study will lay the foundation for testing EGCG as a treatment option for RA and other inflammatory diseases. ..
  61. Neurobiological mechanisms of nicotine reinforcement: Role of the nucleus tractus
    LUIS MIGUEL TUESTA; Fiscal Year: 2012
    ..developed nations, with approximately $160 billion being spent yearly in the United States to cover direct health care costs from resulting diseases...
  62. Economic Consequences of Advanced Testing for Subclinical Cardiovascular Disease
    Leslee J Shaw; Fiscal Year: 2010
    ..We will compare costs in addition to the added benefit of improved detection of heart disease risk using several cardiac biomarkers. ..
  63. Long-acting Growth Hormone for Treating HIV-Associated Adipose Redistribution Syn
    George Cox; Fiscal Year: 2009
  64. Hip Fracture Evaluation Alternatives of Total Hip vs Hemi-arthroplasty (HEALTH)
    Thomas Einhorn; Fiscal Year: 2009 40 years, the number of hip fractures is likely to exceed 500,000 annually, and the estimated annual health care costs will reach a staggering $9.8 billion...
  65. Micro-patterned surfaces for reducing the risk of catheter-associated UTI
    SHRAVANTHI REDDY; Fiscal Year: 2009
  66. Comparing focused ultrasound and uterine artery embolization for uterine fibroids
    Elizabeth A Stewart; Fiscal Year: 2010
    ..The direct health care costs attributable to leiomyomas exceed $2.1 billion annually1...
  67. Injectable, biocompatible poly (vinyl alcohol) hydrogels for tissue bulking
    Gavin Braithwaite; Fiscal Year: 2009
    ..The research proposed here will further develop an innovative injectable hydrogel material that is both biocompatible and non-degradable for use as a tissue bulking agent to treat stress urinary incontinence. ..
  68. The Effects of Vitamin B3 on Traumatic Brain Injury
    MICHAEL HOANE; Fiscal Year: 2009
    ..The associated health care costs from these injuries can be staggering...
  69. Barcoded Magnetic Beads for Rapid Tests of MRSA and Respiratory Viral Panels
    WINSTON Z HO; Fiscal Year: 2010
    ..Over 17,000 MRSA-related hospitalizations end in death. Over $2.5 billion excess health care costs are attributable to MRSA infections...
  70. Keratin biomaterial-based fluid for trauma resuscitation
    LUKE BURNETT; Fiscal Year: 2010
    ..If successful, this new keratin resuscitation fluid can be used by first responders and hospitals to save many victims of trauma-related hemorrhage and shock. ..
    ELIZABETH HENSKE; Fiscal Year: 1999
  72. Novel Breath Test To Detect Early Stage Chronic Pancreatitis
    DAVID A contact WAGNER; Fiscal Year: 2010
    ..Disorders of the pancreas affect more than one million persons in this country with nearly $3 billion in health care costs. The incidence rate of chronic pancreatitis (CP) is rapidly increasing and may be related to expanded ..
  73. Risk prediction of atrial fibrillation: clinical, biological and genetic markers
    EMELIA J contact BENJAMIN; Fiscal Year: 2010
    ..The investigators will develop new methods and predictive tools that will inform clinical decisions and target interventions aimed at the prevention of atrial fibrillation. ..
    Walter Stamm; Fiscal Year: 2007
    An estimated 150 million UTIs occur annually on a global basis, accounting for direct health care costs exceeding 6 billion dollars and making UTIs a very significant public health burden...
    VICTORIA RAVEIS; Fiscal Year: 1999
    ..older spouse's adjustment to widowhood and reducing morbid bereavement outcomes and their associated health care costs in a sample at high risk for poor bereavement outcomes...
  76. Rapid Novel Molecular Detection of Methicillin-Resistant Staphylococcus aureus
  77. Randomized observation study of biologic therapy for rheumatoid arthritis
    LARRY W contact MORELAND; Fiscal Year: 2010
    ..hand, CCE studies that rely on randomized drug trial data do not provide the best estimates of real world health care costs and there is significant disparity between CCE results from randomized versus observational studies in RA ..
  78. Impact of Information Prescriptions on Medication Adherence in ED Patients
    Nancy K Roderer; Fiscal Year: 2010
    ..Poor adherence to medication regimens is associated with worsening of disease, death and increased health care costs in the United States...
  79. Family-Focused Therapy as Early Treatment for Youth at Risk for Bipolar Disorder
    David Miklowitz; Fiscal Year: 2009
  80. Prophylaxis of adrenal insufficiency to prevent CLD
    Kristi Watterberg; Fiscal Year: 2005
    Chronic lung disease (CLD) is a frequent complication of prematurity, resulting in increased health care costs, prolonged hospital stay, frequent rehospitalizations, and compromised growth and development...
  81. A Study of the Factors Influencing Women's Decision about Childbirth
    MARY J REGAN; Fiscal Year: 2010
    ..This study is part of a systematic program of research dedicated to improving women's health and satisfaction with their birthing experience. ..
  82. Developing Web Delivered Coping Skills Training for Women with Alcoholic Partners
    Robert G Rychtarik; Fiscal Year: 2010
    ..In so doing, it has the potential for having a much larger public health impact than conventional face-to-face delivery models, alone. ..
  83. Medicare Advantage?
    Lauren Nicholas; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable]..
  84. Hospital-Physician Gainsharing
    JONATHAN DAVID KETCHAM; Fiscal Year: 2010
    DESCRIPTION (provided by applicant): Health care costs continue to grow quickly in the U.S., but the value of this spending is uncertain...
    Mona Baumgarten; Fiscal Year: 2001
    ..elderly hospital patients constitute an important clinical problem, in terms of frequency, severity, and health care costs. The incidence rate of pressure ulcers among patients aged 65 years or more in acute care settings is ..
  86. Neuro-Cognitive Aspects of Opiate Abuse & Antisocial Behavior
    Jasmin Vassileva; Fiscal Year: 2004
    ..abstract_text> ..