pacific ocean

Summary

Top Publications

  1. ncbi Archaeal dominance in the mesopelagic zone of the Pacific Ocean
    M B Karner
    University of Hawaii, Department of Oceanography, Honolulu 96822, USA
    Nature 409:507-10. 2001
  2. pmc Biogeographical distribution and diversity of microbes in methane hydrate-bearing deep marine sediments on the Pacific Ocean Margin
    Fumio Inagaki
    Subground Animalcule Retrieval Project, Extremobiosphere Research Center, Japan Agency for Marine Earth Science and Technology, Yokosuka 237 0061, Japan
    Proc Natl Acad Sci U S A 103:2815-20. 2006
  3. doi Microbial community structure in the North Pacific ocean
    Mark V Brown
    NASA Astrobiology Institute, University of Hawaii, Honolulu, HI, USA
    ISME J 3:1374-86. 2009
  4. ncbi From anchovies to sardines and back: multidecadal change in the Pacific Ocean
    Francisco P Chavez
    Monterey Bay Aquarium Research Institute, 7700 Sandholdt Road, Moss Landing, CA 95039, USA
    Science 299:217-21. 2003
  5. ncbi Shifts in a Pacific ocean fish assemblage: the potential influence of exploitation
    Phillip S Levin
    NOAA Fisheries Service, Northwest Fisheries Science Center, 2725 Montlake Boulevard E, Seattle, WA 98112, USA
    Conserv Biol 20:1181-90. 2006
  6. ncbi Assessing diversity and biogeography of aerobic anoxygenic phototrophic bacteria in surface waters of the Atlantic and Pacific Oceans using the Global Ocean Sampling expedition metagenomes
    Natalya Yutin
    Biology Department, Technion Israel Institute of Technology, Haifa 32000, Israel
    Environ Microbiol 9:1464-75. 2007
  7. pmc Groups without cultured representatives dominate eukaryotic picophytoplankton in the oligotrophic South East Pacific Ocean
    Xiao li Shi
    UPMC Paris 06 and CNRS, UMR 7144, Station Biologique de Roscoff, Roscoff, France
    PLoS ONE 4:e7657. 2009
  8. ncbi Distinct patterns of genetic differentiation among annelids of eastern Pacific hydrothermal vents
    L A Hurtado
    Monterey Bay Aquarium Research Institute, 7700 Sandholdt Road, Moss Landing, CA 95039, USA
    Mol Ecol 13:2603-15. 2004
  9. ncbi Controls on tropical Pacific Ocean productivity revealed through nutrient stress diagnostics
    Michael J Behrenfeld
    Department of Botany and Plant Pathology, Cordley Hall 2082, Oregon State University, Corvallis, Oregon 97331 2902, USA
    Nature 442:1025-8. 2006
  10. ncbi Unicellular cyanobacteria fix N2 in the subtropical North Pacific Ocean
    J P Zehr
    Department of Ocean Sciences and Institute of Marine Sciences, University of California, Santa Cruz, California 95064, USA
    Nature 412:635-8. 2001

Research Grants

  1. Regional Biocontainment Laboratory
    JAMES GAINES; Fiscal Year: 2005
  2. Regional Biocontainment Laboratory
    JAMES GAINES; Fiscal Year: 2007
  3. Pacific Center for Emerging Infectious Diseases Research
    Richard Yanagihara; Fiscal Year: 2010
  4. CENTER OF CLINICAL RESEARCH EXCELLENCE
    David Easa; Fiscal Year: 2003
  5. PRENATAL PCB EXPOSURE AND COGNITIVE DEVELOPMENT
    Paul Stewart; Fiscal Year: 2006
  6. CORTICO-STRIATAL SUBSTRATES OF DEFICIENT STARTLE GATING
    Neal R Swerdlow; Fiscal Year: 2010
  7. SCienceLab
    Bert Ely; Fiscal Year: 2009
  8. Symbiotic colonization of host mucus by Vibrio fischeri
    Mark Mandel; Fiscal Year: 2007
  9. DOPAMINERGIC SUBSTRATES OF STARTLE GATING ACROSS SPECIES
    Neal Swerdlow; Fiscal Year: 2009
  10. SDF-1 and neurogenesis in HIV-1 associated dementia
    Jialin Zheng; Fiscal Year: 2009

Detail Information

Publications225 found, 100 shown here

  1. ncbi Archaeal dominance in the mesopelagic zone of the Pacific Ocean
    M B Karner
    University of Hawaii, Department of Oceanography, Honolulu 96822, USA
    Nature 409:507-10. 2001
    ..3 x 10(28) archaeal cells, and 3.1 x 10(28) bacterial cells. Our data suggest that pelagic crenarchaeota represent one of the ocean's single most abundant cell types...
  2. pmc Biogeographical distribution and diversity of microbes in methane hydrate-bearing deep marine sediments on the Pacific Ocean Margin
    Fumio Inagaki
    Subground Animalcule Retrieval Project, Extremobiosphere Research Center, Japan Agency for Marine Earth Science and Technology, Yokosuka 237 0061, Japan
    Proc Natl Acad Sci U S A 103:2815-20. 2006
    ..distribution of microbes and their phylogenetic diversities in deeply buried marine sediments of the Pacific Ocean Margins...
  3. doi Microbial community structure in the North Pacific ocean
    Mark V Brown
    NASA Astrobiology Institute, University of Hawaii, Honolulu, HI, USA
    ISME J 3:1374-86. 2009
    ....
  4. ncbi From anchovies to sardines and back: multidecadal change in the Pacific Ocean
    Francisco P Chavez
    Monterey Bay Aquarium Research Institute, 7700 Sandholdt Road, Moss Landing, CA 95039, USA
    Science 299:217-21. 2003
    In the Pacific Ocean, air and ocean temperatures, atmospheric carbon dioxide, landings of anchovies and sardines, and the productivity of coastal and open ocean ecosystems have varied over periods of about 50 years...
  5. ncbi Shifts in a Pacific ocean fish assemblage: the potential influence of exploitation
    Phillip S Levin
    NOAA Fisheries Service, Northwest Fisheries Science Center, 2725 Montlake Boulevard E, Seattle, WA 98112, USA
    Conserv Biol 20:1181-90. 2006
    ..Our results are disquieting because they raise the possibility that fishing-induced phase shifts in fish communities may affect the recovery offishes, even after the implementation of severe fishing restrictions...
  6. ncbi Assessing diversity and biogeography of aerobic anoxygenic phototrophic bacteria in surface waters of the Atlantic and Pacific Oceans using the Global Ocean Sampling expedition metagenomes
    Natalya Yutin
    Biology Department, Technion Israel Institute of Technology, Haifa 32000, Israel
    Environ Microbiol 9:1464-75. 2007
    ..Our results support the notion that marine AAnP populations are complex and dynamic, and compose an important fraction of bacterioplankton assemblages in certain oceanic areas...
  7. pmc Groups without cultured representatives dominate eukaryotic picophytoplankton in the oligotrophic South East Pacific Ocean
    Xiao li Shi
    UPMC Paris 06 and CNRS, UMR 7144, Station Biologique de Roscoff, Roscoff, France
    PLoS ONE 4:e7657. 2009
    ....
  8. ncbi Distinct patterns of genetic differentiation among annelids of eastern Pacific hydrothermal vents
    L A Hurtado
    Monterey Bay Aquarium Research Institute, 7700 Sandholdt Road, Moss Landing, CA 95039, USA
    Mol Ecol 13:2603-15. 2004
    ..The present findings are compared with similar evidence from codistributed species of annelids, molluscs and crustaceans to identify potential dispersal filters in these eastern Pacific ridge systems...
  9. ncbi Controls on tropical Pacific Ocean productivity revealed through nutrient stress diagnostics
    Michael J Behrenfeld
    Department of Botany and Plant Pathology, Cordley Hall 2082, Oregon State University, Corvallis, Oregon 97331 2902, USA
    Nature 442:1025-8. 2006
    ..and use these relationships to evaluate the factors that constrain phytoplankton growth in the tropical Pacific Ocean on an unprecedented spatial scale...
  10. ncbi Unicellular cyanobacteria fix N2 in the subtropical North Pacific Ocean
    J P Zehr
    Department of Ocean Sciences and Institute of Marine Sciences, University of California, Santa Cruz, California 95064, USA
    Nature 412:635-8. 2001
    ..Here we show that there are unicellular cyanobacteria in the open ocean that are expressing nitrogenase, and are abundant enough to potentially have a significant role in N dynamics...
  11. ncbi Dispersal barriers and isolation among deep-sea mussel populations (Mytilidae: Bathymodiolus) from eastern Pacific hydrothermal vents
    Y Won
    Monterey Bay Aquarium Research Institute, 7700 Sandholdt Road, Moss Landing, CA 95039 0628, USA
    Mol Ecol 12:169-84. 2003
    ..structure, gene flow and isolation in vent-endemic mussels of the genus Bathymodiolus from the eastern Pacific Ocean. Mussels were sampled from localities including the Galapagos Rift (GAR, 0 degrees 48' N; 86 degrees 10' W) ..
  12. pmc Extreme endurance flights by landbirds crossing the Pacific Ocean: ecological corridor rather than barrier?
    Robert E Gill
    USGS Alaska Science Center, 4210 University Drive, Anchorage, AK 99508, USA
    Proc Biol Sci 276:447-57. 2009
    ..Limosa lapponica baueri), shorebirds whose breeding and non-breeding areas are separated by the vast central Pacific Ocean. Seven females with surgically implanted transmitters flew non-stop 8,117-11,680 km (10153+/-1043 s.d...
  13. doi Microbial community gene expression within colonies of the diazotroph, Trichodesmium, from the Southwest Pacific Ocean
    Ian Hewson
    Department of Ocean Sciences, University of California Santa Cruz, Santa Cruz, CA, USA
    ISME J 3:1286-300. 2009
    ..of microbial gene utilization within colonies of Trichodesmium collected during a bloom in the Southwest Pacific Ocean in April 2007. The survey generated 5711-day and 5385-night putative mRNA reads...
  14. ncbi Metal levels in feathers of 12 species of seabirds from midway atoll in the northern Pacific Ocean
    J Burger
    Division of Life Sciences and Environmental and Occupational Health Sciences Institute, Rutgers University, Piscataway, NJ 08854 8082, USA
    Sci Total Environ 257:37-52. 2000
    ..chromium, manganese, selenium, and tin in the feathers of birds nesting on Midway Atoll in the northern Pacific Ocean. We test the null hypothesis that there are no interspecific differences in the levels of metals in the ..
  15. doi Molecular and ultrastructural characterization of two ascomycetes found on sunken wood off Vanuatu islands in the deep Pacific ocean
    Joelle Dupont
    Département Systématique and Evolution UMR 7205, Museum national d histoire naturelle, CP 39, 57 rue Cuvier, 75231 Paris Cedex 05, France
    Mycol Res 113:1351-64. 2009
    ..found together with Oceanitis scuticella, on small twigs and sugar cane debris trawled from the bottom of the Pacific Ocean off Vanuatu Islands...
  16. doi Improved culturability of SAR11 strains in dilution-to-extinction culturing from the East Sea, West Pacific Ocean
    Jaeho Song
    Division of Biology and Ocean Sciences, Inha University, Incheon, Korea
    FEMS Microbiol Lett 295:141-7. 2009
    ..low temperature was applied in an effort to cultivate major bacterioplankton lineages in the East Sea, Western Pacific Ocean. Five to 10 cells were inoculated into each well of 48-well plates, followed by the incubation of the plates ..
  17. ncbi Quorum sensing antagonism from marine organisms
    Mette Elena Skindersoe
    Department of Bioscience and Technology, Technical University of Denmark, Lyngby, Denmark
    Mar Biotechnol (NY) 10:56-63. 2008
    ....
  18. ncbi Satellite tagging and cardiac physiology reveal niche expansion in salmon sharks
    Kevin C Weng
    Tuna Research and Conservation Center, Stanford University, Hopkins Marine Station, 120 Oceanview Boulevard, Pacific Grove, CA 93950, USA
    Science 310:104-6. 2005
    ....
  19. ncbi Distinguishing random environmental fluctuations from ecological catastrophes for the North Pacific Ocean
    Chih Hao Hsieh
    Scripps Institution of Oceanography, University of California, San Diego, La Jolla, California 92093 0202, USA
    Nature 435:336-40. 2005
    ..Here we show that time series observations of key physical variables for the North Pacific Ocean that seem to show these behaviours are not deterministically nonlinear, and are best described as linear ..
  20. ncbi Biomass, size, and trophic status of top predators in the Pacific Ocean
    John Sibert
    Joint Institute for Marine and Atmospheric Research, University of Hawaii, Honolulu, HI 96822, USA
    Science 314:1773-6. 2006
    Fisheries have removed at least 50 million tons of tuna and other top-level predators from the Pacific Ocean pelagic ecosystem since 1950, leading to concerns about a catastrophic reduction in population biomass and the collapse of ..
  21. ncbi Shewanella loihica sp. nov., isolated from iron-rich microbial mats in the Pacific Ocean
    Haichun Gao
    Environmental Sciences Division, Oak Ridge National Laboratory, Oak Ridge, TN, USA
    Int J Syst Evol Microbiol 56:1911-6. 2006
    ..strain, PV-4(T), isolated from a microbial mat located at a hydrothermal vent of Loihi Seamount in the Pacific Ocean, has been characterized...
  22. ncbi Oceanic 18S rDNA sequences from picoplankton reveal unsuspected eukaryotic diversity
    S Y Moon-van der Staay
    Station Biologique, , Roscoff, France
    Nature 409:607-10. 2001
    ..ribosomal RNA gene derived from a picoplanktonic assemblage collected at a depth of 75 m in the equatorial Pacific Ocean, and show that there is a high diversity of picoeukaryotes...
  23. doi A novel lipopeptide produced by a Pacific Ocean deep-sea bacterium, Rhodococcus sp. TW53
    F Peng
    Key Laboratory of Marine Biogenetic Resources, Third Institute of Oceanography, State Oceanic Administration, Xiamen, Fujian, China
    J Appl Microbiol 105:698-705. 2008
    Our goal was to find a novel, biosurfactant-producing bacterium from Pacific Ocean deep-sea sediments.
  24. ncbi High rates of N2 fixation by unicellular diazotrophs in the oligotrophic Pacific Ocean
    Joseph P Montoya
    School of Biology, Georgia Institute of Technology, Atlanta, Georgia 30332, USA
    Nature 430:1027-32. 2004
    ..Direct measurements of 15N2 fixation by small diazotrophs in various parts of the Pacific Ocean, including the waters off Hawaii where the unicellular diazotrophs were first characterized, show that N2 ..
  25. ncbi Measurement and implications of nonphotochemically generated superoxide in the equatorial Pacific Ocean
    Andrew L Rose
    Centre for Water and Waste Technology, School of Civil and Environmental Engineering, The University of New South Wales, Sydney, Australia
    Environ Sci Technol 42:2387-93. 2008
    ..in the water column of the Costa Rica Dome (CRD) seasonal upwelling region of the eastern equatorial Pacific Ocean. After 0...
  26. pmc Light dependence of [3H]leucine incorporation in the oligotrophic North Pacific ocean
    Matthew J Church
    School of Marine Science, The College of William and Mary, Gloucester Point, Virginia 23062, USA
    Appl Environ Microbiol 70:4079-87. 2004
    ..The results of these experiments revealed that sunlight directly influences bacterial growth in this open-ocean ecosystem...
  27. doi Early Palaeogene temperature evolution of the southwest Pacific Ocean
    Peter K Bijl
    Palaeoecology, Institute of Environmental Biology, Faculty of Science, Laboratory of Palaeobotany and Palynology, Utrecht University, Budapestlaan 4, 3584 CD Utrecht, The Netherlands
    Nature 461:776-9. 2009
    ....
  28. pmc High abundances of aerobic anoxygenic photosynthetic bacteria in the South Pacific Ocean
    Raphael Lami
    Observatoire Océanologique de Banyuls, Universite Pierre et Marie Curie Paris 6, UMR7621 INSU CNRS, BP44, F 66650 Banyuls sur Mer, France
    Appl Environ Microbiol 73:4198-205. 2007
    ..We investigated the abundance of AAP bacteria across the South Pacific Ocean, including the center of the gyre, the most oligotrophic water body of the world ocean...
  29. ncbi Constrained circulation at Endeavour ridge facilitates colonization by vent larvae
    Richard E Thomson
    Institute of Ocean Sciences, 9860 West Saanich Road, Sidney, British Columbia, V8L 4B2, Canada
    Nature 424:545-9. 2003
    ..Larvae are then exported preferentially down-ridge during regional flow events that intermittently over-ride the currents within the valley...
  30. ncbi Long-term change in benthopelagic fish abundance in the abyssal northeast Pacific Ocean
    D M Bailey
    Marine Biology Research Division, Scripps Institution of Oceanography, University of California San Diego, 9500 Gilman Drive, La Jolla, California 92093 0202, USA
    Ecology 87:549-55. 2006
    ..This study provides a rare opportunity to study the long-term dynamics of an unexploited marine fish population and suggests a dominant role for bottom-up control in this system...
  31. ncbi Metagenomic analysis of coastal RNA virus communities
    Alexander I Culley
    Department of Botany, University of British Columbia, 3529 6270 University Boulevard, Vancouver, BC V6T 1Z4, Canada
    Science 312:1795-8. 2006
    ..Our results show that the oceans are a reservoir of previously unknown RNA viruses...
  32. doi Biogenic origin of polymetallic nodules from the Clarion-Clipperton Zone in the Eastern Pacific Ocean: electron microscopic and EDX evidence
    Xiaohong Wang
    Laboratory for Earth Surface Processes, Ministry of Education, Peking University, 100871 Beijing, China
    Mar Biotechnol (NY) 11:99-108. 2009
    ..They were collected from the Clarion-Clipperton Zone in the Eastern Pacific Ocean and are composed of Mn (23.9%), Cu (0.69%), Ni (1.02%), Fe (10.9%), and Co (0.29%)...
  33. ncbi Climate-driven changes to the atmospheric CO2 sink in the subtropical North Pacific Ocean
    John E Dore
    Department of Oceanography, School of Ocean and Earth Science and Technology, University of Hawaii, 1000 Pope Road, Honolulu, Hawaii 96822, USA
    Nature 424:754-7. 2003
    ..a 13-year time series of oceanic carbon dioxide measurements from station ALOHA in the subtropical North Pacific Ocean near Hawaii, and find a significant decrease in the strength of the carbon dioxide sink over the period 1989-..
  34. ncbi Rhodotorula pacifica sp. nov., a novel yeast species from sediment collected on the deep-sea floor of the north-west Pacific Ocean
    Takahiko Nagahama
    Extremobiosphere Research Center, Japan Agency for Marine Earth Science and Technology JAMSTEC, 2 15 Natsushima cho, Yokosuka 237 0061, Japan
    Int J Syst Evol Microbiol 56:295-9. 2006
    ..species of the genus Rhodotorula was isolated from sediments collected on the deep-sea floor in the north-west Pacific Ocean. Strains SY-96T, isolated from the Yap Trench, and SY-246, isolated from the Iheya Ridge, had almost identical ..
  35. doi Redescription of Rhadinorhynchus ornatus (Acanthocephala: Rhadinorhynchidae) from skipjack tuna, Katsuwonus pelamis, collected in the Pacific Ocean off South America, with special reference to new morphological features
    Omar M Amin
    Institute of Parasitic Diseases, P O Box 28372, Tempe, Arizona 85285, USA
    J Parasitol 95:656-64. 2009
    ..collected from the small intestine of skipjack tuna, Katsuwonus pelamis (Linnaeus), in the high seas of the Pacific Ocean off the west coast of South America (new parasite locality record) and described using optical microscopy and ..
  36. ncbi Egg brooding by deep-sea octopuses in the North Pacific Ocean
    J R Voight
    Department of Zoology, Field Museum of Natural History, Chicago, Illinois 60605, USA
    Biol Bull 198:94-100. 2000
    ..The size and shape of boreholes in 19 of over 400 thyasirid clam shells collected from Baby Bare support the hypothesis that octopuses had preyed upon the clams...
  37. ncbi Incidence of novel and potentially archaeal nitrogenase genes in the deep Northeast Pacific Ocean
    Mausmi P Mehta
    University of Washington, School of Oceanography, Seattle, WA 98195, USA
    Environ Microbiol 7:1525-34. 2005
    ..We propose that these unique nifH genes may be localized to archaea that circulate through the nitrogen-poor subseafloor at the mid-ocean ridge as part of their life cycle...
  38. ncbi Artificial radionuclides database in the Pacific Ocean: HAM database
    Michio Aoyama
    Geochemical Research Department, Meteorological Research Institute, Nagamine 1 1, Tsukuba, Ibaraki 305 0052, Japan
    ScientificWorldJournal 4:200-15. 2004
    The database "Historical Artificial Radionuclides in the Pacific Ocean and its Marginal Seas", or HAM database, has been created...
  39. ncbi Trace metals, stable isotope ratios, and trophic relations in seabirds from the North Pacific Ocean
    John E Elliott
    Canadian Wildlife Service, Environment Canada, Pacific Wildlife Research Centre, Delta British Columbia
    Environ Toxicol Chem 24:3099-105. 2005
    ..puffin (Fratercula corniculata) were collected opportunistically by an experimental fishery in the North Pacific Ocean. Two species each of petrels (Oceanodroma leucorhoa, Oceanodroma furcata) and auklets (Ptychoramphus aleuticus,..
  40. ncbi Mesoscale eddies drive increased silica export in the subtropical Pacific Ocean
    Claudia R Benitez-Nelson
    Department of Geological Sciences and Marine Science Program, University of South Carolina, Columbia, SC 29208, USA
    Science 316:1017-21. 2007
    ..Instead, the system functioned as a selective silica pump. Strong trophic coupling and inefficient organic export may be general characteristics of community perturbation responses in the warm waters of the Pacific Ocean.
  41. doi Globally distributed uncultivated oceanic N2-fixing cyanobacteria lack oxygenic photosystem II
    Jonathan P Zehr
    Ocean Sciences Department, University of California, Santa Cruz, 1156 High Street, Santa Cruz, CA 95064, USA
    Science 322:1110-2. 2008
    ....
  42. pmc Phocine distemper virus in northern sea otters in the Pacific Ocean, Alaska, USA
    Tracey Goldstein
    Wildlife Health Center, School of Veterinary Medicine, University of California, Davis, California 95616, USA
    Emerg Infect Dis 15:925-7. 2009
    ..virus (PDV) has caused 2 epidemics in harbor seals in the Atlantic Ocean but had never been identified in any Pacific Ocean species...
  43. ncbi Pleistocene isolation and recent gene flow in Haliotis asinina, an Indo-Pacific vetigastropod with limited dispersal capacity
    Benardine Jeffrey
    School of Integrative Biology, University of Queensland, Brisbane, QLD, Australia
    Mol Ecol 16:289-304. 2007
    ..asinina phylogeography...
  44. pmc Thermal stress and coral cover as drivers of coral disease outbreaks
    John F Bruno
    Department of Marine Sciences, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America
    PLoS Biol 5:e124. 2007
    ..Our results indicate that the frequency of temperature anomalies, which is predicted to increase in most tropical oceans, can increase the susceptibility of corals to disease, leading to outbreaks where corals are abundant...
  45. pmc Temporal patterns of nitrogenase gene (nifH) expression in the oligotrophic North Pacific Ocean
    Matthew J Church
    Department of Oceanography, University of Hawaii, Honolulu, HI 96822, USA
    Appl Environ Microbiol 71:5362-70. 2005
    ..planktonic nitrogenase genes (nifH) in the upper ocean (0 to 175 m) at Station ALOHA in the oligotrophic North Pacific Ocean. Clone libraries constructed from reverse-transcribed PCR-amplified mRNA revealed six unique phylotypes...
  46. ncbi Loktanella agnita sp. nov. and Loktanella rosea sp. nov., from the north-west Pacific Ocean
    Elena P Ivanova
    Swinburne University of Technology, Hawthorn, Vic 3122, Australia
    Int J Syst Evol Microbiol 55:2203-7. 2005
    ..aerobic bacteria were isolated from sea-water and sediment samples collected in Chazhma Bay (Sea of Japan, Pacific Ocean)...
  47. ncbi Prokaryote diversity and virus abundance in shallow hydrothermal vents of the Mediterranean Sea (Panarea Island) and the Pacific Ocean (north Sulawesi-Indonesia)
    E Manini
    Institute of Marine Science, ISMAR CNR, Largo Fiera della Pesca, 60125 Ancona, Italy
    Microb Ecol 55:626-39. 2008
    ..of four different shallow-water hydrothermal vents (three located in the Mediterranean Sea and one in the Pacific Ocean)...
  48. pmc Sequence analysis of marine virus communities reveals that groups of related algal viruses are widely distributed in nature
    Steven M Short
    Department of Botany, University of British Columbia, 6720 University Boulevard, Vancouver, British Columbia, Canada, V6T 1Z4
    Appl Environ Microbiol 68:1290-6. 2002
    ..Natural algal virus communities were obtained from coastal sites in the Pacific Ocean in British Columbia, Canada, and the Southern Ocean near the Antarctic peninsula...
  49. doi Directional dispersal between mid-ocean ridges: deep-ocean circulation and gene flow in Ridgeia piscesae
    C R Young
    Monterey Bay Aquarium Research Institute, 7700 Sandholdt Road, Moss Landing, CA 95039 9644, USA
    Mol Ecol 17:1718-31. 2008
    ..Together, these data suggest that the northern vent fields may experience a higher frequency of habitat turnover and consequently more rapid losses of genetic diversity...
  50. doi Temporal variation of Synechococcus clades at a coastal Pacific Ocean monitoring site
    Vera Tai
    Marine Biology Research Division, Scripps Institution of Oceanography, University of California, La Jolla, San Diego, CA 92093 0202, USA
    ISME J 3:903-15. 2009
    ..from the Scripps Institution of Oceanography pier (La Jolla, CA, USA), a coastal site in the northeastern Pacific Ocean. Synechococcus from clades I and IV were dominant throughout the time series and correlated with total ..
  51. doi Photosynthetic picoeukaryote community structure in the South East Pacific Ocean encompassing the most oligotrophic waters on Earth
    Cécile Lepère
    Department of Biological Sciences, University of Warwick, Coventry, UK
    Environ Microbiol 11:3105-17. 2009
    ..Here, we analysed PPE community structure along a transect in the South East Pacific Ocean (BIOSOPE cruise) that encompassed a large trophic gradient, including hyper-oligotrophic waters in the South ..
  52. ncbi Phylogeographical structure of the Dover sole Microstomus pacificus: the larval retention hypothesis and genetic divergence along the deep continental slope of the northeastern Pacific Ocean
    C A Stepien
    Department of Biology, Case Western Reserve University, Cleveland, OH 44106 7080, USA
    Mol Ecol 8:923-39. 1999
    ..pacificus (Teleostei: Pleuronectidae), were examined along the continental slope of the north-eastern Pacific Ocean using sequences of the left domain of the mitochondrial DNA (mtDNA) control region...
  53. ncbi Reconciling patterns of inter-ocean molecular variance from four classes of molecular markers in blue marlin (Makaira nigricans)
    V P Buonaccorsi
    School of Marine Science, Virginia Institute of Marine Science, College of William and Mary, Gloucester Point, VA, USA
    Mol Ecol 10:1179-96. 2001
    ..Mitochondrial and microsatellite loci revealed striking phylogeographic partitioning among Atlantic and Pacific Ocean samples...
  54. ncbi Community genomics among stratified microbial assemblages in the ocean's interior
    Edward F DeLong
    Massachusetts Institute of Technology, Cambridge, MA 02139, USA
    Science 311:496-503. 2006
    ..Comparative genomic analyses of stratified microbial communities have the potential to provide significant insight into higher-order community organization and dynamics...
  55. ncbi Genetic divergence between Atlantic and Indo-Pacific stocks of bigeye tuna (Thunnus obesus) and admixture around South Africa
    S Chow
    National Research Institute of Far Seas Fisheries, 5 7 1 Orido, Shimizu 424 8633, Japan
    Mol Ecol 9:221-7. 2000
    ..The simple and diagnostic genetic marker found in this study can be used to estimate mixing ratios between Atlantic and Indian stocks around South Africa...
  56. ncbi Production of manoalide and its analogues by the sponge Luffariella variabilis Is hardwired
    Piers Ettinger-Epstein
    School of Marine and Tropical Biology, James Cook University, Townsville, Queensland, Australia
    Mar Biotechnol (NY) 10:64-74. 2008
    ..However, these ratios varied between individuals, with some individuals consistently producing high levels of manoalide and manoalide monoacetate, providing the potential for selection of high-yielding stocks...
  57. pmc Sequential megafaunal collapse in the North Pacific Ocean: an ongoing legacy of industrial whaling?
    A M Springer
    Institute of Marine Science, University of Alaska, Fairbanks, AK 99775, USA
    Proc Natl Acad Sci U S A 100:12223-8. 2003
    ..of seals, sea lions, and sea otters have sequentially collapsed over large areas of the northern North Pacific Ocean and southern Bering Sea during the last several decades...
  58. doi Nitrogen fixation in an anticyclonic eddy in the oligotrophic North Pacific Ocean
    Allison A Fong
    Department of Oceanography, University of Hawaii, Honolulu, HI 96822, USA
    ISME J 2:663-76. 2008
    ..These results suggest that mesoscale physical variability can play an important role in modifying the abundances of N(2) fixing microorganisms and associated rates of N(2) fixation in open ocean ecosystems...
  59. ncbi Culturable marine actinomycete diversity from tropical Pacific Ocean sediments
    Paul R Jensen
    Center for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, University of California San Diego, La Jolla, CA 92093 0204, USA
    Environ Microbiol 7:1039-48. 2005
    ..These bacteria can be readily cultured using low nutrient media and represent an unexplored resource for pharmaceutical drug discovery...
  60. ncbi Isolation by distance and vicariance drive genetic structure of a coral reef fish in the Pacific Ocean
    S Planes
    Ecole Pratique des Hautes Etudes ESA CNRS 8046, Universite de Perpignan, France
    Evolution 56:378-99. 2002
    ..The genetic structure of A. triostegus throughout the tropical Pacific Ocean revealed a strong geographic pattern...
  61. ncbi Morbillivirus infection in stranded common dolphins from the Pacific Ocean
    T H Reidarson
    Sea World of California, San Diego 92109, USA
    J Wildl Dis 34:771-6. 1998
    ..The first individual to strand survived and was released back into the Pacific Ocean 14 mo later...
  62. pmc Migratory shearwaters integrate oceanic resources across the Pacific Ocean in an endless summer
    Scott A Shaffer
    Ecology and Evolutionary Biology, University of California, Santa Cruz, CA 95064, USA
    Proc Natl Acad Sci U S A 103:12799-802. 2006
    ..Tracks (262+/-23 days) reveal that shearwaters fly across the entire Pacific Ocean in a figure-eight pattern while traveling 64,037+/-9,779 km roundtrip, the longest animal migration ever ..
  63. ncbi Key role of selective viral-induced mortality in determining marine bacterial community composition
    T Bouvier
    CNRS UMR5119, Universite de Montpellier II, Case 093, Place Eugene Bataillon, 34095 Montpellier Cedex 5, France
    Environ Microbiol 9:287-97. 2007
    ..We further suggest that this mode of regulation may influence not just the distribution of single strains but of entire phylogenetic groups...
  64. pmc Defining DNA-based operational taxonomic units for microbial-eukaryote ecology
    David A Caron
    Department of Biological Sciences, University of Southern California, 3616 Trousdale Parkway, Los Angeles, CA 90089 0371, USA
    Appl Environ Microbiol 75:5797-808. 2009
    ..A total of 388 operational taxonomic units were observed for 2,207 sequences obtained from samples collected in the western North Atlantic and eastern North Pacific oceans...
  65. ncbi Antibacterial and antilarval activity of deep-sea bacteria from sediments of the West Pacific Ocean
    Ying Xu
    Department of Biology Coastal Marine Laboratory, Hong Kong University of Science and Technology HKUST, Clear Water Bay, Kowloon, Hong Kong
    Biofouling 23:131-7. 2007
    ..study, crude ethyl acetate extracts of 176 strains of deep-sea bacteria, isolated from sediments of the West Pacific Ocean, were screened for their antibacterial activity against four test bacterial strains isolated from marine ..
  66. ncbi Thermosipho melanesiensis sp. nov., a new thermophilic anaerobic bacterium belonging to the order Thermotogales, isolated from deep-sea hydrothermal vents in the southwestern Pacific Ocean
    E Antoine
    Laboratoire de Biotechnologie des Microorganismes Hydrothermaux, DRV VP, Center IFREMER de Brest, France
    Int J Syst Bacteriol 47:1118-23. 1997
    ..from the gills of a deep-sea vent hydrothermal mussel, Bathymodiolus brevior, from the Lau Basin (Southwestern Pacific Ocean)...
  67. ncbi Inverse relationship between F and microsatellite polymorphism in the marine fish, walleye pollock (Theragra chalcogramma): implications for resolving weak population structure
    P T O'Reilly
    Bedford Institute of Oceanography, 1 Challenger Drive, Dartmouth, Nova Scotia B2Y 4A2, USA
    Mol Ecol 13:1799-814. 2004
    ..Genetic differentiation at 14 microsatellite loci among six putative populations from across the North Pacific Ocean and Bering Sea was weak but significant on large geographical scales and conformed to an isolation-by-distance ..
  68. ncbi In situ cardiac performance of Pacific bluefin tuna hearts in response to acute temperature change
    Jason M Blank
    Department of Biological Sciences, Stanford University, Oceanview Boulevard, Pacific Grove, CA 93950, USA
    J Exp Biol 207:881-90. 2004
    ..In situ data from Pacific bluefin are compared to in situ measurements of cardiac performance in yellowfin tuna and preliminary results from albacore tuna...
  69. ncbi Two new species of hydrothermal vent crabs of the genus Bythograea from the southern East Pacific Rise and from the Galapagos Rift (Crustacea Decapoda Brachyura Bythograeidae)
    Danièle Guinot
    Département Milieux et Peuplements Aquatiques, Museum national d histoire naturelle, 61, rue Buffon 75005 Paris, France
    C R Biol 326:423-39. 2003
    ..galapagensis is the sister species of B. thermydron Williams. Bythograea is now composed of six described species, all endemic to hydrothermal vents along the East Pacific Rise and from the Galapagos Rift...
  70. ncbi Marine debris collects within the North Pacific Subtropical Convergence Zone
    William G Pichel
    National Oceanic and Atmospheric Administration NOAA, National Environmental Satellite, Data, and Information Service, Room 102 WWB, 5200 Auth Road, Camp Springs, MD 20746, USA
    Mar Pollut Bull 54:1207-11. 2007
    ..A Debris Estimated Likelihood Index (DELI) was developed to predict where high concentrations of debris would be most likely in the North Pacific during spring and early summer...
  71. ncbi Migration, isolation, and speciation of hydrothermal vent limpets (Gastropoda; Lepetodrilidae) across the Blanco Transform Fault
    Shannon B Johnson
    Monterey Bay Aquarium Research Institute, 7700 Sandholdt Road, Moss Landing, California, USA
    Biol Bull 210:140-57. 2006
    ..and Blanco Transform Fault separate the Explorer, Juan de Fuca, and Gorda ridge systems of the northeastern Pacific Ocean. To test whether such offsets in the ridge axis create barriers to along-axis dispersal of the endemic ..
  72. doi Archaeoglobus infectus sp. nov., a novel thermophilic, chemolithoheterotrophic archaeon isolated from a deep-sea rock collected at Suiyo Seamount, Izu-Bonin Arc, western Pacific Ocean
    Koji Mori
    NITE Biological Resource Center NBRC, National Institute of Technology and Evaluation NITE, 2 5 8 Kazusakamatari, Kisarazu, Chiba 292 0818, Japan
    Int J Syst Evol Microbiol 58:810-6. 2008
    ..from a rock sample collected from a deep-sea hydrothermal field in Suiyo Seamount, Izu-Bonin Arc, western Pacific Ocean. Cells of the isolate were irregular cocci with single flagella and exhibited blue-green fluorescence at 436 ..
  73. ncbi Rapid stepwise onset of Antarctic glaciation and deeper calcite compensation in the Pacific Ocean
    Helen K Coxall
    Southampton Oceanography Centre, School of Ocean and Earth Science, European Way, Southampton SO14 3ZH, UK
    Nature 433:53-7. 2005
    ..records of calcium carbonate content as well as carbon and oxygen isotopic compositions from the tropical Pacific Ocean that cover the Eocene/Oligocene boundary...
  74. pmc The shifting baseline of northern fur seal ecology in the northeast Pacific Ocean
    Seth D Newsome
    Geophysical Laboratory, Carnegie Institution of Washington, 5251 Broad Branch Road NW, Washington, DC 20015, USA
    Proc Natl Acad Sci U S A 104:9709-14. 2007
    ..P., long before European contact. The relative roles of human hunting versus climatic factors in explaining this ecological shift are unclear, as more paleoclimate information is needed from the coastal zone...
  75. doi Vertical distribution and characterization of aerobic phototrophic bacteria at the Juan de Fuca Ridge in the Pacific Ocean
    Christopher Rathgeber
    Department of Microbiology, The University of Manitoba, 422 Buller Building, Winnipeg, MB, Canada, R3T 2N2
    Photosynth Res 97:235-44. 2008
    ..anoxygenic phototrophic bacteria was investigated at five sites at or near the Juan de Fuca Ridge in the Pacific Ocean. Twelve similar strains of obligately aerobic phototrophic bacteria were isolated in pure culture, from depths ..
  76. ncbi Fisheries productivity in the northeastern Pacific Ocean over the past 2,200 years
    Bruce P Finney
    Institute of Marine Science, University of Alaska Fairbanks, Fairbanks, Alaska 99775 7220, USA
    Nature 416:729-33. 2002
    ..The coherent patterns observed across large regions demonstrate the strong role of climatic forcing in regulating northeastern Pacific fish stocks...
  77. ncbi Toxaphene and other persistent organochlorine pesticides in three species of albatrosses from the north and south Pacific Ocean
    Derek C G Muir
    National Water Research Institute, Environment Canada, Burlington, Ontario
    Environ Toxicol Chem 21:413-23. 2002
    ..Diomedea immutabilis) and in fat and eggs of blackfooted albatross (Diomedea nigripes) from the central north Pacific Ocean. The HCH isomers and chlordane- and DDT-related compounds were also determined in eggs of northern royal ..
  78. ncbi Expanded niche for white sharks
    Andre M Boustany
    Tuna Research and Conservation Center, Stanford University and Monterey Bay Aquarium, Hopkins Marine Station, Pacific Grove, California 93950, USA
    Nature 415:35-6. 2002
    ..Here we report the tracking of movements of white sharks by using pop-up satellite archival tags, which reveal that their migratory movements, depth and ambient thermal ranges are wider than was previously thought...
  79. ncbi Coral record of increased sediment flux to the inner Great Barrier Reef since European settlement
    Malcolm McCulloch
    Research School of Earth Sciences, Australian National University, Canberra 0200, Australia
    Nature 421:727-30. 2003
    ....
  80. ncbi Global change: Monsoon linkages
    Rainer Zahn
    Nature 421:324-5. 2003
  81. ncbi Fluids from aging ocean crust that support microbial life
    James P Cowen
    Department of Oceanography, School of Ocean and Earth Science and Technology, University of Hawaii, Honolulu, HI 96822, USA
    Science 299:120-3. 2003
    ....
  82. ncbi Detection of glycolate oxidase gene glcD diversity among cultured and environmental marine bacteria
    W W Y Lau
    School of Oceanography, University of Washington, Seattle, WA 98195, USA
    Environ Microbiol 8:1688-702. 2006
    ..Glycolate is produced in marine environments mainly by phytoplankton. Examination of glcD diversity will aid in understanding the influence of phytoplankton on bacterial community structure...
  83. pmc Microbial community in a sediment-hosted CO2 lake of the southern Okinawa Trough hydrothermal system
    Fumio Inagaki
    Subground Animalcule Retrieval SUGAR Program, Extremobiosphere Research Center, Japan Agency for Marine Earth Science and Technology JAMSTEC, Yokosuka 237 0061, Japan
    Proc Natl Acad Sci U S A 103:14164-9. 2006
    ..Clearly, the Yonaguni Knoll is an exceptional natural laboratory for the study of consequences of CO2 disposal as well as of natural CO2 reservoirs as potential microbial habitats on early Earth and other celestial bodies...
  84. ncbi Nitrogen fixation at 92 degrees C by a hydrothermal vent archaeon
    Mausmi P Mehta
    School of Oceanography, University of Washington, Seattle, WA 98195, USA
    Science 314:1783-6. 2006
    ..This increase in the temperature limit of nitrogen fixation could reveal a broader range of conditions for life in the subseafloor biosphere and other nitrogen-limited ecosystems than previously estimated...
  85. ncbi Microbial population structures in the deep marine biosphere
    Julie A Huber
    Josephine Bay Paul Center, Marine Biological Laboratory, 7 MBL Street, Woods Hole, MA 02543, USA
    Science 318:97-100. 2007
    ....
  86. ncbi Methanococcus aeolicus sp. nov., a mesophilic, methanogenic archaeon from shallow and deep marine sediments
    Melissa M Kendall
    Biology Department, Portland State University, PO Box 751, Portland, OR 97207 0751, USA
    Int J Syst Evol Microbiol 56:1525-9. 2006
    ..The name Methanococcus aeolicus sp. nov. is proposed, with strain Nankai-3(T) (=OCM 812(T)=DSM 17508(T)) as the type strain...
  87. doi Different Planctomycetes diversity patterns in latitudinal surface seawater of the open sea and in sediment
    Qinglong Shu
    State Key Laboratory of Marine Environmental Science, Xiamen University, Xiamen, 361005, P R China
    J Microbiol 46:154-9. 2008
    ..was applied to investigate the diversity of Planctomycetes in latitudinal surface seawater of the Western Pacific Ocean. The results revealed that the Pirellula-Rhodopirellula-Blastopirellula clade dominated the Planctomycetes ..
  88. ncbi [Adaptation of organisms to extreme conditions of deep-sea hydrothermal vents]
    Zoran Minic
    Laboratoire de Biochimie des Signaux Régulateurs Cellulaires et Moléculaires, FRE 2621, CNRS, Universite Pierre et Marie Curie Paris 6, 96, bd Raspail, 75006 Paris, France
    C R Biol 329:527-40. 2006
    ..Moreover to survive in these environments, living organisms have developed various strategies to protect themselves against toxic molecules such as H2S and heavy metals...
  89. pmc Cyanobacteria associated with coral black band disease in Caribbean and Indo-Pacific Reefs
    Jorge Frias-Lopez
    Department of Geology, University of Illinois, Urbana 61801, USA
    Appl Environ Microbiol 69:2409-13. 2003
    ....
  90. ncbi Strong top-down control in southern California kelp forest ecosystems
    Benjamin S Halpern
    National Center for Ecological Analysis and Synthesis, 735 State Street, Santa Barbara, CA 93101, USA
    Science 312:1230-2. 2006
    ..Management of top-down influences such as fishing may be more important in coastal marine ecosystems, particularly in kelp forest systems, than is commonly thought...
  91. ncbi Oceanographic basis of the global surface distribution of Prochlorococcus ecotypes
    Heather A Bouman
    Laboratorio de Procesos Oceanográficos y Clima, Departamento de Oceanografia, and Centro de Investigación Oceanográfica en el Pacífico Sur Oriental, Universidad de Concepcion, Casilla 160 C, Concepcion, Chile
    Science 312:918-21. 2006
    ....
  92. pmc Isolation and characterization of novel psychrophilic, neutrophilic, Fe-oxidizing, chemolithoautotrophic alpha- and gamma-proteobacteria from the deep sea
    K J Edwards
    Geomicrobiology Group, Department of Marine Chemistry and Geochemistry, Woods Hole Oceanographic Institution, McLean Lab, MS 8, Woods Hole, MA 02543, USA
    Appl Environ Microbiol 69:2906-13. 2003
    ..This study provides further evidence for the evolutionarily widespread capacity for Fe oxidation among bacteria and suggests that FeOB may play an unrecognized geomicrobiological role in rock weathering in the deep sea...
  93. ncbi Genomic islands and the ecology and evolution of Prochlorococcus
    Maureen L Coleman
    Massachusetts Institute of Technology, Department of Civil and Environmental Engineering, 15 Vassar Street, Cambridge, MA 02139, USA
    Science 311:1768-70. 2006
    ..Genomic islands in this free-living photoautotroph share features with pathogenicity islands of parasitic bacteria, suggesting a general mechanism for niche differentiation in microbial species...
  94. ncbi Zobellia amurskyensis sp. nov., Zobellia laminariae sp. nov. and Zobellia russellii sp. nov., novel marine bacteria of the family Flavobacteriaceae
    Olga I Nedashkovskaya
    Pacific Institute of Bioorganic Chemistry of the Far Eastern Branch of the Russian Academy of Sciences, Prospekt 100 let Vladivostoku 159, 690022, Vladivostok, Russia
    Int J Syst Evol Microbiol 54:1643-8. 2004
    ..nov. and Zobellia russellii sp. nov. are proposed, with KMM 3526T (= LMG 22069T = CCUG 47080T), KMM 3676T (= LMG 22070T = CCUG 47083T) and KMM 3677T (= LMG 22071T = CCUG 47084T), respectively, as the type strains...
  95. ncbi Climate change and latitudinal patterns of intertidal thermal stress
    Brian Helmuth
    University of South Carolina, Department of Biological Sciences and Marine Sciences Program, Columbia, SC 29208, USA
    Science 298:1015-7. 2002
    ..Patterns of exposure to extreme climatic conditions are temporally variable, and tidal predictions suggest that in the next 3 to 5 years "hot spots" are likely to appear at several northern sites...
  96. ncbi Thalassospira xiamenensis sp. nov. and Thalassospira profundimaris sp. nov
    Chenli Liu
    Key Laboratory of Marine Biogenetic Resources, Third Institute of Oceanography, State Oceanic Administration, PR China
    Int J Syst Evol Microbiol 57:316-20. 2007
    ..from the surface water of a waste-oil pool in a coastal dock and from a deep-sea sediment sample from the West Pacific Ocean, respectively...
  97. pmc Trends in selenium utilization in marine microbial world revealed through the analysis of the global ocean sampling (GOS) project
    Yan Zhang
    Department of Biochemistry, University of Nebraska, Lincoln, Nebraska, USA
    PLoS Genet 4:e1000095. 2008
    ..Overall, our study provides insights into global trends in microbial selenium utilization in marine environments...
  98. doi One-third of reef-building corals face elevated extinction risk from climate change and local impacts
    Kent E Carpenter
    IUCN International Union for Conservation of Nature Species Programme Species Survival Commission SSC, Biological Sciences, Old Dominion University, Norfolk, VA 23529, USA
    Science 321:560-3. 2008
    ..Our results emphasize the widespread plight of coral reefs and the urgent need to enact conservation measures...
  99. ncbi Paenibacillus donghaensis sp. nov., a xylan-degrading and nitrogen-fixing bacterium isolated from East Sea sediment
    Jeong Hwa Choi
    Department of Microbiology and Biotechnology Research, Chungbuk National University, Cheongju 361 763, Korea
    J Microbiol Biotechnol 18:189-93. 2008
    ..Based on the phylogenetic, phenotypic, and chemotaxonomic characteristics, strain JH8T would appear to belong to a novel species, for which the name Paenibacillus donghaensis sp. nov. is proposed (type strain =KCTC 13049T=LMG 23780T)...
  100. doi Isolation, gene detection and solvent tolerance of benzene, toluene and xylene degrading bacteria from nearshore surface water and Pacific Ocean sediment
    Lin Wang
    Key Laboratory of Marine Biogenetic Resources, The Third Institute of Oceanography, State Oceanic Administration, Daxue Road 178, Xiamen 361005, Fujian, People s Republic of China
    Extremophiles 12:335-42. 2008
    BTX (benzene, toluene and xylene) degrading bacteria were isolated from Pacific Ocean sediment and nearshore surface water...
  101. ncbi Distinct distribution pattern of abundance and diversity of aerobic anoxygenic phototrophic bacteria in the global ocean
    Nianzhi Jiao
    National Key Laboratory of Marine Environmental Sciences, Xiamen University, Xiamen 361005, China
    Environ Microbiol 9:3091-9. 2007
    ..Our results suggest that AAPB abundance and diversity follow opposite trends from oligotrophic to eutrophic regimes in the ocean...

Research Grants74

  1. Regional Biocontainment Laboratory
    JAMES GAINES; Fiscal Year: 2005
    Located approximately 4,000 km from both North America and the islands of Polynesia in the middle of the Pacific Ocean, Hawaii serves as a principal U.S. gateway to and from Asia, and as a major tourist destination for people worldwide...
  2. Regional Biocontainment Laboratory
    JAMES GAINES; Fiscal Year: 2007
    Located approximately 4,000 km from both North America and the islands of Polynesia in the middle of the Pacific Ocean, Hawaii serves as a principal U.S. gateway to and from Asia, and as a major tourist destination for people worldwide...
  3. Pacific Center for Emerging Infectious Diseases Research
    Richard Yanagihara; Fiscal Year: 2010
    Located in the westernmost IDeA-eligible state in the middle of the Pacific Ocean, approximately 4,000 km from North America and the major island nations of Oceania, the University of Hawaii at Manoa (UH-Manoa) is strategically ..
  4. CENTER OF CLINICAL RESEARCH EXCELLENCE
    David Easa; Fiscal Year: 2003
    ..Far removed from the mainland USA as a result of its geographic isolation in the Pacific Ocean, the collaborations and affiliations that could naturally develop in a community setting with neighboring ..
  5. PRENATAL PCB EXPOSURE AND COGNITIVE DEVELOPMENT
    Paul Stewart; Fiscal Year: 2006
    ..In addition, school records for each child's New York State mandatory testing of English Language Arts and Math will be obtained for comparative analysis. ..
  6. CORTICO-STRIATAL SUBSTRATES OF DEFICIENT STARTLE GATING
    Neal R Swerdlow; Fiscal Year: 2010
    ..New information from these studies will be a foundation for innovative models of the pathophysiology of schizophrenia and other inherited neuropsychiatric disorders, and for prospective strategies for novel drug development. ..
  7. SCienceLab
    Bert Ely; Fiscal Year: 2009
    ..To address this problem, SCienceLab provides an opportunity for students to spend a day experiencing research and interacting with students who are working in a biomedical research laboratory. ..
  8. Symbiotic colonization of host mucus by Vibrio fischeri
    Mark Mandel; Fiscal Year: 2007
    ..This benign infection provides a natural environment in which to study these processes with minimal perturbation, which may also yield insights into how pathogenic infections are mediated in a variety of hosts. ..
  9. DOPAMINERGIC SUBSTRATES OF STARTLE GATING ACROSS SPECIES
    Neal Swerdlow; Fiscal Year: 2009
    ..More generally, these studies will leverage findings from MH 59803 years 1-5, to extend the important process of examining the neurochemistry of sensorimotor gating processes that fundamentally shape behavior and cognition in humans. ..
  10. SDF-1 and neurogenesis in HIV-1 associated dementia
    Jialin Zheng; Fiscal Year: 2009
    ..This work will elucidate mechanisms through which neurogenesis is affected by HAD, which could identify new therapeutic strategies for treating HAD and other neurodegenerative disorders. ..
  11. PRENATAL PCB EXPOSURE AND COGNITIVE DEVELOPMENT
    Paul Stewart; Fiscal Year: 2007
    ..Specific Aim 3) To assess the stability of the association between prenatal PCB exposure and Global Intelligence (IQ) through re-assessment of IQ at 15 years of age ..
  12. DOPAMINERGIC SUBSTRATES OF STARTLE GATING ACROSS SPECIES
    Neal R Swerdlow; Fiscal Year: 2011
    ..The findings will inform studies searching for the genes associated with dopamine-linked disorders of impaired sensorimotor gating in humans. ..
  13. SOUTH CAROLINA POST-BACCALAUREATE RESEARCH EDUCATION
    Bert Ely; Fiscal Year: 2007
    ..4) To help the students establish relationships among peers and faculty at USC and elsewhere in the research community so that the PREP scholar has well-defined career goals. ..
  14. PRENATAL PCB EXPOSURE AND COGNITIVE DEVELOPMENT
    Paul Stewart; Fiscal Year: 2007
    ..Description (Provided by Applicant) ..
  15. PRENATAL PCB EXPOSURE AND COGNITIVE DEVELOPMENT
    Paul Stewart; Fiscal Year: 2003
    ..abstract_text> ..
  16. SCIENCE LABORATORY
    Bert Ely; Fiscal Year: 2005
    ..During the summer, a graduate course will be offered to science teachers that will include mentored instruction of students participating in the laboratory investigations at SCienceCamp. ..
  17. CORTICO-STRIATAL SUBSTRATES OF DEFICIENT STARTLE GATING
    Neal Swerdlow; Fiscal Year: 2007
    ..New information from these studies will be a foundation for innovative models of the pathophysiology of schizophrenia and other inherited neuropsychiatric disorders, and for prospective strategies for novel drug development. ..
  18. NEURAL CIRCUITRY OF SENSORIMOTOR GATING ACROSS SPECIES
    Neal Swerdlow; Fiscal Year: 2006
    ....
  19. SDF-1 and neurogenesis in HIV-1 associated dementia
    Jialin Zheng; Fiscal Year: 2009
    ..This work will elucidate mechanisms through which neurogenesis is affected by HAD, which could identify new therapeutic strategies for treating HAD and other neurodegenerative disorders. ..
  20. Glutaminase: neurotoxic link in HIV-1 Associated Dementia
    JIALIN CHARLES ZHENG; Fiscal Year: 2010
    ..This work will elucidate mechanisms through which glutaminase play in neuronal injury during HAND, which could identify new therapeutic strategies for treating HAND and other neurodegenerative disorders. ..
  21. SDF-1 and neurogenesis in HIV-1 associated dementia
    JIALIN CHARLES ZHENG; Fiscal Year: 2010
    ..This work will elucidate mechanisms through which neurogenesis is affected by HAD, which could identify new therapeutic strategies for treating HAD and other neurodegenerative disorders. ..
  22. Macrophage Activation, Chemokines, and HIV Dementia
    Jialin Zheng; Fiscal Year: 2004
    ..This proposal integrates disciplines of virology, immunology, and receptor pharmacology in a mechanistic study of HAD. ..
  23. TRAIL and glutaminase: neurotoxic link in HIV-1 Dementia
    Jialin Zheng; Fiscal Year: 2007
    ..The elucidation of the mechanisms by which TRAIL-TRAIL receptors and glutaminase interact during MP mediated neuronal injury may open up new therapeutic ideas for disease treatment or prevention. ..
  24. TRAIL and glutaminase: neurotoxic link in HIV-1 Dementia
    Jialin Zheng; Fiscal Year: 2009
    ..The elucidation of the mechanisms by which TRAIL-TRAIL receptors and glutaminase interact during MP mediated neuronal injury may open up new therapeutic ideas for disease treatment or prevention. ..